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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HLF_TEF

Z-value: 0.69

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Transcription factors associated with HLF_TEF

Gene Symbol Gene ID Gene Info
HLF
ENSG00000108924.9 HLF transcription factor, PAR bZIP family member
TEF
ENSG00000167074.10 TEF transcription factor, PAR bZIP family member

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
TEFhg19_v2_chr22_+_41777927_417779710.834.2e-02Click!
HLFhg19_v2_chr17_+_53342311_53342400-0.374.7e-01Click!

Activity profile of HLF_TEF motif

Sorted Z-values of HLF_TEF motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_7844312 0.70 ENST00000377541.1
PER3
period circadian clock 3
chr4_+_104346194 0.66 ENST00000510200.1
RP11-328K4.1
RP11-328K4.1
chr1_+_154378049 0.52 ENST00000512471.1
IL6R
interleukin 6 receptor
chr1_+_154377669 0.50 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr12_-_46121554 0.48 ENST00000609803.1
LINC00938
long intergenic non-protein coding RNA 938
chr3_-_158390282 0.46 ENST00000264265.3
LXN
latexin
chr8_-_27469383 0.43 ENST00000519742.1
CLU
clusterin
chr4_-_153274078 0.36 ENST00000263981.5
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr8_-_27468717 0.35 ENST00000520796.1
ENST00000520491.1
CLU
clusterin
chr8_-_102217515 0.35 ENST00000520347.1
ENST00000523922.1
ENST00000520984.1
ZNF706
zinc finger protein 706
chr8_-_102216925 0.34 ENST00000517844.1
ZNF706
zinc finger protein 706
chr8_-_27469196 0.32 ENST00000546343.1
ENST00000560566.1
CLU
clusterin
chr8_+_110552337 0.31 ENST00000337573.5
EBAG9
estrogen receptor binding site associated, antigen, 9
chr7_-_111428957 0.31 ENST00000417165.1
DOCK4
dedicator of cytokinesis 4
chr3_+_88188254 0.28 ENST00000309495.5
ZNF654
zinc finger protein 654
chr1_+_92632542 0.28 ENST00000409154.4
ENST00000370378.4
KIAA1107
KIAA1107
chr13_-_29292956 0.28 ENST00000266943.6
SLC46A3
solute carrier family 46, member 3
chr8_-_27468945 0.26 ENST00000405140.3
CLU
clusterin
chr8_-_27468842 0.26 ENST00000523500.1
CLU
clusterin
chr15_+_49913201 0.25 ENST00000329873.5
ENST00000558653.1
ENST00000559164.1
ENST00000560632.1
ENST00000559405.1
ENST00000251250.6
DTWD1
DTW domain containing 1
chr9_-_130712995 0.25 ENST00000373084.4
FAM102A
family with sequence similarity 102, member A
chr17_-_19651654 0.24 ENST00000395555.3
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr3_+_195869379 0.23 ENST00000457079.1
LINC00885
long intergenic non-protein coding RNA 885
chr7_+_90032667 0.23 ENST00000496677.1
ENST00000287916.4
ENST00000535571.1
ENST00000394604.1
ENST00000394605.2
CLDN12
claudin 12
chr2_-_201936302 0.23 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
FAM126B
family with sequence similarity 126, member B
chr1_-_244013384 0.22 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr14_+_67708344 0.21 ENST00000557237.1
MPP5
membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
chr7_+_23146271 0.21 ENST00000545771.1
KLHL7
kelch-like family member 7
chr19_+_52076425 0.21 ENST00000436511.2
ZNF175
zinc finger protein 175
chr8_-_102217796 0.21 ENST00000519744.1
ENST00000311212.4
ENST00000521272.1
ENST00000519882.1
ZNF706
zinc finger protein 706
chr1_-_226496772 0.21 ENST00000359525.2
ENST00000460719.1
LIN9
lin-9 homolog (C. elegans)
chr2_-_225362533 0.21 ENST00000451538.1
CUL3
cullin 3
chr17_-_19651668 0.21 ENST00000494157.2
ENST00000225740.6
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr13_-_38172863 0.20 ENST00000541481.1
ENST00000379743.4
ENST00000379742.4
ENST00000379749.4
ENST00000541179.1
ENST00000379747.4
POSTN
periostin, osteoblast specific factor
chr18_+_21032781 0.18 ENST00000339486.3
RIOK3
RIO kinase 3
chr20_+_4666882 0.18 ENST00000379440.4
ENST00000430350.2
PRNP
prion protein
chr2_-_214014959 0.18 ENST00000442445.1
ENST00000457361.1
ENST00000342002.2
IKZF2
IKAROS family zinc finger 2 (Helios)
chr2_+_191208601 0.18 ENST00000413239.1
ENST00000431594.1
ENST00000444194.1
INPP1
inositol polyphosphate-1-phosphatase
chr4_+_157997273 0.18 ENST00000541722.1
ENST00000512619.1
GLRB
glycine receptor, beta
chr12_-_120966943 0.18 ENST00000552443.1
ENST00000547736.1
ENST00000445328.2
ENST00000547943.1
ENST00000288532.6
COQ5
coenzyme Q5 homolog, methyltransferase (S. cerevisiae)
chr3_-_45883558 0.17 ENST00000445698.1
ENST00000296135.6
LZTFL1
leucine zipper transcription factor-like 1
chr21_-_30365136 0.17 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
LTN1
listerin E3 ubiquitin protein ligase 1
chr10_+_94050913 0.17 ENST00000358935.2
MARCH5
membrane-associated ring finger (C3HC4) 5
chr2_+_191208656 0.17 ENST00000458647.1
INPP1
inositol polyphosphate-1-phosphatase
chr6_-_86353510 0.17 ENST00000444272.1
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr1_+_144989309 0.16 ENST00000596396.1
AL590452.1
Uncharacterized protein
chr8_+_110552831 0.16 ENST00000530629.1
EBAG9
estrogen receptor binding site associated, antigen, 9
chr17_+_73089382 0.16 ENST00000538213.2
ENST00000584118.1
SLC16A5
solute carrier family 16 (monocarboxylate transporter), member 5
chr5_-_111091948 0.16 ENST00000447165.2
NREP
neuronal regeneration related protein
chr17_-_61850894 0.16 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
CCDC47
coiled-coil domain containing 47
chr21_+_35107346 0.16 ENST00000456489.1
ITSN1
intersectin 1 (SH3 domain protein)
chr3_+_101504200 0.15 ENST00000422132.1
NXPE3
neurexophilin and PC-esterase domain family, member 3
chr2_+_46769798 0.15 ENST00000238738.4
RHOQ
ras homolog family member Q
chr2_+_191208791 0.15 ENST00000423767.1
ENST00000451089.1
INPP1
inositol polyphosphate-1-phosphatase
chr8_+_42396936 0.15 ENST00000416469.2
SMIM19
small integral membrane protein 19
chr10_+_86004802 0.15 ENST00000359452.4
ENST00000358110.5
ENST00000372092.3
RGR
retinal G protein coupled receptor
chr2_+_183989157 0.14 ENST00000541912.1
NUP35
nucleoporin 35kDa
chr2_+_65663812 0.14 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1
AC074391.1
chr21_+_35736302 0.14 ENST00000290310.3
KCNE2
potassium voltage-gated channel, Isk-related family, member 2
chr15_-_66084428 0.14 ENST00000443035.3
ENST00000431932.2
DENND4A
DENN/MADD domain containing 4A
chr14_+_75894391 0.13 ENST00000419727.2
JDP2
Jun dimerization protein 2
chr3_+_154797877 0.13 ENST00000462745.1
ENST00000493237.1
MME
membrane metallo-endopeptidase
chr11_+_105948216 0.13 ENST00000278618.4
AASDHPPT
aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
chr4_+_144257915 0.13 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr8_-_112248400 0.13 ENST00000519506.1
ENST00000522778.1
RP11-946L20.4
RP11-946L20.4
chr19_-_41356347 0.12 ENST00000301141.5
CYP2A6
cytochrome P450, family 2, subfamily A, polypeptide 6
chr7_+_23145884 0.12 ENST00000409689.1
ENST00000410047.1
KLHL7
kelch-like family member 7
chr1_+_196621156 0.12 ENST00000359637.2
CFH
complement factor H
chr16_+_3508096 0.12 ENST00000577013.1
ENST00000570819.1
NAA60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr5_-_140013275 0.12 ENST00000512545.1
ENST00000302014.6
ENST00000401743.2
CD14
CD14 molecule
chr11_-_33795893 0.12 ENST00000526785.1
ENST00000534136.1
ENST00000265651.3
ENST00000530401.1
ENST00000448981.2
FBXO3
F-box protein 3
chr16_+_70680439 0.12 ENST00000288098.2
IL34
interleukin 34
chr4_+_144258021 0.11 ENST00000262994.4
GAB1
GRB2-associated binding protein 1
chr14_+_60716159 0.11 ENST00000325658.3
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr1_+_174933899 0.11 ENST00000367688.3
RABGAP1L
RAB GTPase activating protein 1-like
chr2_+_183989083 0.10 ENST00000295119.4
NUP35
nucleoporin 35kDa
chr10_-_65028817 0.10 ENST00000542921.1
JMJD1C
jumonji domain containing 1C
chr1_-_226496898 0.10 ENST00000481685.1
LIN9
lin-9 homolog (C. elegans)
chr10_-_65028938 0.10 ENST00000402544.1
JMJD1C
jumonji domain containing 1C
chr17_-_39538550 0.10 ENST00000394001.1
KRT34
keratin 34
chr8_+_90914073 0.10 ENST00000297438.2
OSGIN2
oxidative stress induced growth inhibitor family member 2
chr4_+_144258288 0.10 ENST00000514639.1
GAB1
GRB2-associated binding protein 1
chr3_-_196910721 0.10 ENST00000443183.1
DLG1
discs, large homolog 1 (Drosophila)
chr22_-_50221160 0.10 ENST00000404760.1
BRD1
bromodomain containing 1
chr3_+_182983126 0.10 ENST00000481531.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr5_+_95997918 0.10 ENST00000395812.2
ENST00000395813.1
ENST00000359176.4
ENST00000325674.7
CAST
calpastatin
chr5_+_172332220 0.10 ENST00000518247.1
ENST00000326654.2
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr12_-_122017542 0.10 ENST00000446152.2
KDM2B
lysine (K)-specific demethylase 2B
chr4_+_48807155 0.10 ENST00000504654.1
OCIAD1
OCIA domain containing 1
chr10_-_91295304 0.09 ENST00000341233.4
ENST00000371790.4
SLC16A12
solute carrier family 16, member 12
chr1_-_167883327 0.09 ENST00000476818.2
ENST00000367851.4
ENST00000367848.1
ADCY10
adenylate cyclase 10 (soluble)
chr16_+_3508063 0.09 ENST00000576787.1
ENST00000572942.1
ENST00000576916.1
ENST00000575076.1
ENST00000572131.1
NAA60
N(alpha)-acetyltransferase 60, NatF catalytic subunit
chr8_-_103424986 0.09 ENST00000521922.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr14_+_60715928 0.09 ENST00000395076.4
PPM1A
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr3_+_154798162 0.09 ENST00000360490.2
MME
membrane metallo-endopeptidase
chr1_-_247094628 0.09 ENST00000366508.1
ENST00000326225.3
ENST00000391829.2
AHCTF1
AT hook containing transcription factor 1
chr8_+_94752349 0.09 ENST00000391680.1
RBM12B-AS1
RBM12B antisense RNA 1
chr1_-_114430169 0.09 ENST00000393316.3
BCL2L15
BCL2-like 15
chr1_-_161207986 0.09 ENST00000506209.1
ENST00000367980.2
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr11_-_62313090 0.09 ENST00000528508.1
ENST00000533365.1
AHNAK
AHNAK nucleoprotein
chr3_+_182983090 0.09 ENST00000465010.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr15_-_49255632 0.09 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr2_+_179184955 0.08 ENST00000315022.2
OSBPL6
oxysterol binding protein-like 6
chr7_+_135347215 0.08 ENST00000507606.1
C7orf73
chromosome 7 open reading frame 73
chr9_-_123639445 0.08 ENST00000312189.6
PHF19
PHD finger protein 19
chr9_-_88356789 0.08 ENST00000357081.3
ENST00000376081.4
ENST00000337006.4
ENST00000376109.3
AGTPBP1
ATP/GTP binding protein 1
chr8_-_103424916 0.08 ENST00000220959.4
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr3_+_186383741 0.08 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr19_-_2042065 0.08 ENST00000591588.1
ENST00000591142.1
MKNK2
MAP kinase interacting serine/threonine kinase 2
chr5_-_179050066 0.07 ENST00000329433.6
ENST00000510411.1
HNRNPH1
heterogeneous nuclear ribonucleoprotein H1 (H)
chr7_+_120629653 0.07 ENST00000450913.2
ENST00000340646.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr2_+_198318217 0.07 ENST00000409398.1
COQ10B
coenzyme Q10 homolog B (S. cerevisiae)
chr5_+_95998070 0.07 ENST00000421689.2
ENST00000510756.1
ENST00000512620.1
CAST
calpastatin
chr10_-_82049424 0.07 ENST00000372213.3
MAT1A
methionine adenosyltransferase I, alpha
chr9_-_123639600 0.07 ENST00000373896.3
PHF19
PHD finger protein 19
chr2_-_207078154 0.07 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr11_+_123986069 0.07 ENST00000456829.2
ENST00000361352.5
ENST00000449321.1
ENST00000392748.1
ENST00000360334.4
ENST00000392744.4
VWA5A
von Willebrand factor A domain containing 5A
chr2_+_103378472 0.07 ENST00000412401.2
TMEM182
transmembrane protein 182
chr8_-_103425047 0.07 ENST00000520539.1
UBR5
ubiquitin protein ligase E3 component n-recognin 5
chr13_-_45010939 0.06 ENST00000261489.2
TSC22D1
TSC22 domain family, member 1
chr5_+_12574944 0.06 ENST00000505877.1
ENST00000513051.1
ENST00000505196.1
CT49
cancer/testis antigen 49 (non-protein coding)
chr4_-_65275162 0.06 ENST00000381210.3
ENST00000507440.1
TECRL
trans-2,3-enoyl-CoA reductase-like
chr11_-_105948129 0.06 ENST00000526793.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr20_-_49547910 0.06 ENST00000396032.3
ADNP
activity-dependent neuroprotector homeobox
chr3_+_62304648 0.06 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
C3orf14
chromosome 3 open reading frame 14
chr5_-_54830871 0.06 ENST00000307259.8
PPAP2A
phosphatidic acid phosphatase type 2A
chr7_-_44887620 0.06 ENST00000349299.3
ENST00000521529.1
ENST00000308153.4
ENST00000350771.3
ENST00000222690.6
ENST00000381124.5
ENST00000437072.1
ENST00000446531.1
H2AFV
H2A histone family, member V
chr6_+_36238237 0.06 ENST00000457797.1
ENST00000394571.2
PNPLA1
patatin-like phospholipase domain containing 1
chr3_-_196910477 0.06 ENST00000447466.1
DLG1
discs, large homolog 1 (Drosophila)
chr5_-_43557791 0.06 ENST00000338972.4
ENST00000511321.1
ENST00000515338.1
PAIP1
poly(A) binding protein interacting protein 1
chr19_+_42254885 0.06 ENST00000595740.1
CEACAM6
carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
chr8_+_70404996 0.05 ENST00000402687.4
ENST00000419716.3
SULF1
sulfatase 1
chr2_-_100106419 0.05 ENST00000393445.3
ENST00000258428.3
REV1
REV1, polymerase (DNA directed)
chr18_-_55288973 0.05 ENST00000423481.2
ENST00000587194.1
ENST00000591599.1
ENST00000588661.1
NARS
asparaginyl-tRNA synthetase
chr1_-_101491319 0.05 ENST00000342173.7
ENST00000488176.1
ENST00000370109.3
DPH5
diphthamide biosynthesis 5
chr1_-_161208013 0.05 ENST00000515452.1
ENST00000367983.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr6_+_53948221 0.05 ENST00000460844.2
MLIP
muscular LMNA-interacting protein
chr17_-_19651598 0.05 ENST00000570414.1
ALDH3A1
aldehyde dehydrogenase 3 family, member A1
chr1_+_45212051 0.05 ENST00000372222.3
KIF2C
kinesin family member 2C
chr4_+_110354928 0.05 ENST00000504968.2
ENST00000399100.2
ENST00000265175.5
SEC24B
SEC24 family member B
chr11_-_105948040 0.05 ENST00000534815.1
KBTBD3
kelch repeat and BTB (POZ) domain containing 3
chr5_+_150404904 0.05 ENST00000521632.1
GPX3
glutathione peroxidase 3 (plasma)
chr2_+_191208196 0.05 ENST00000392329.2
ENST00000322522.4
ENST00000430311.1
ENST00000541441.1
INPP1
inositol polyphosphate-1-phosphatase
chr4_+_41937131 0.05 ENST00000504986.1
ENST00000508448.1
ENST00000513702.1
ENST00000325094.5
TMEM33
transmembrane protein 33
chr18_+_3262954 0.04 ENST00000584539.1
MYL12B
myosin, light chain 12B, regulatory
chr5_+_49963239 0.04 ENST00000505554.1
PARP8
poly (ADP-ribose) polymerase family, member 8
chr11_-_77185094 0.04 ENST00000278568.4
ENST00000356341.3
PAK1
p21 protein (Cdc42/Rac)-activated kinase 1
chr1_+_45212074 0.04 ENST00000372217.1
KIF2C
kinesin family member 2C
chr9_-_88356733 0.04 ENST00000376083.3
AGTPBP1
ATP/GTP binding protein 1
chr22_-_29457832 0.04 ENST00000216071.4
C22orf31
chromosome 22 open reading frame 31
chr12_-_71031185 0.04 ENST00000548122.1
ENST00000551525.1
ENST00000550358.1
PTPRB
protein tyrosine phosphatase, receptor type, B
chr1_-_161207875 0.04 ENST00000512372.1
ENST00000437437.2
ENST00000442691.2
ENST00000412844.2
ENST00000428574.2
ENST00000505005.1
ENST00000508740.1
ENST00000508387.1
ENST00000504010.1
ENST00000511676.1
ENST00000502985.1
ENST00000367981.3
ENST00000515621.1
ENST00000511944.1
ENST00000511748.1
ENST00000367984.4
ENST00000367985.3
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr13_+_28813645 0.04 ENST00000282391.5
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr10_-_94050820 0.04 ENST00000265997.4
CPEB3
cytoplasmic polyadenylation element binding protein 3
chr12_-_88423164 0.04 ENST00000298699.2
ENST00000550553.1
C12orf50
chromosome 12 open reading frame 50
chr6_-_30043539 0.04 ENST00000376751.3
ENST00000244360.6
RNF39
ring finger protein 39
chr4_+_139694701 0.04 ENST00000502606.1
RP11-98O2.1
RP11-98O2.1
chr4_+_96012614 0.04 ENST00000264568.4
BMPR1B
bone morphogenetic protein receptor, type IB
chr15_+_58430368 0.04 ENST00000558772.1
ENST00000219919.4
AQP9
aquaporin 9
chr2_-_101925055 0.04 ENST00000295317.3
RNF149
ring finger protein 149
chr16_-_30102547 0.04 ENST00000279386.2
TBX6
T-box 6
chr3_-_58200398 0.03 ENST00000318316.3
ENST00000460422.1
ENST00000483681.1
DNASE1L3
deoxyribonuclease I-like 3
chr17_-_41984835 0.03 ENST00000520406.1
ENST00000518478.1
ENST00000522172.1
ENST00000461854.1
ENST00000521178.1
ENST00000520305.1
ENST00000523501.1
ENST00000520241.1
MPP2
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chr8_+_107738240 0.03 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr4_+_96012585 0.03 ENST00000502683.1
BMPR1B
bone morphogenetic protein receptor, type IB
chr1_-_161207953 0.03 ENST00000367982.4
NR1I3
nuclear receptor subfamily 1, group I, member 3
chr3_-_55539287 0.03 ENST00000472238.1
RP11-875H7.5
RP11-875H7.5
chr7_-_15601595 0.03 ENST00000342526.3
AGMO
alkylglycerol monooxygenase
chr7_-_141401951 0.03 ENST00000536163.1
KIAA1147
KIAA1147
chr2_-_99279928 0.03 ENST00000414521.2
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr17_-_42144949 0.03 ENST00000591247.1
LSM12
LSM12 homolog (S. cerevisiae)
chr8_-_102218292 0.03 ENST00000518336.1
ENST00000520454.1
ZNF706
zinc finger protein 706
chr1_+_65613513 0.03 ENST00000395334.2
AK4
adenylate kinase 4
chr2_+_198318147 0.03 ENST00000263960.2
COQ10B
coenzyme Q10 homolog B (S. cerevisiae)
chr5_+_95997769 0.03 ENST00000338252.3
ENST00000508830.1
CAST
calpastatin
chr3_+_62304712 0.03 ENST00000494481.1
C3orf14
chromosome 3 open reading frame 14
chr9_-_95298314 0.03 ENST00000344604.5
ENST00000375540.1
ECM2
extracellular matrix protein 2, female organ and adipocyte specific
chr21_+_40824003 0.03 ENST00000452550.1
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr19_-_4065730 0.03 ENST00000601588.1
ZBTB7A
zinc finger and BTB domain containing 7A
chr2_-_239197201 0.03 ENST00000254658.3
PER2
period circadian clock 2
chr20_-_49547731 0.03 ENST00000396029.3
ADNP
activity-dependent neuroprotector homeobox
chr3_+_141103634 0.03 ENST00000507722.1
ZBTB38
zinc finger and BTB domain containing 38
chr5_-_140013241 0.03 ENST00000519715.1
CD14
CD14 molecule
chr19_+_1450112 0.02 ENST00000590469.1
ENST00000233607.2
ENST00000238483.4
ENST00000590877.1
APC2
adenomatosis polyposis coli 2
chr10_+_90660832 0.02 ENST00000371924.1
STAMBPL1
STAM binding protein-like 1
chr14_-_23285069 0.02 ENST00000554758.1
ENST00000397528.4
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr4_-_70725856 0.02 ENST00000226444.3
SULT1E1
sulfotransferase family 1E, estrogen-preferring, member 1
chr17_+_61851504 0.02 ENST00000359353.5
ENST00000389924.2
DDX42
DEAD (Asp-Glu-Ala-Asp) box helicase 42
chr9_-_123639304 0.02 ENST00000436309.1
PHF19
PHD finger protein 19
chr4_+_26344754 0.02 ENST00000515573.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr19_-_35992780 0.02 ENST00000593342.1
ENST00000601650.1
ENST00000408915.2
DMKN
dermokine
chr9_+_110045537 0.02 ENST00000358015.3
RAD23B
RAD23 homolog B (S. cerevisiae)
chr5_+_95997885 0.02 ENST00000511097.2
CAST
calpastatin
chr1_-_150552006 0.02 ENST00000307940.3
ENST00000369026.2
MCL1
myeloid cell leukemia sequence 1 (BCL2-related)
chr17_+_11501748 0.02 ENST00000262442.4
ENST00000579828.1
DNAH9
dynein, axonemal, heavy chain 9
chr5_+_34757309 0.02 ENST00000397449.1
RAI14
retinoic acid induced 14
chr14_-_67826538 0.02 ENST00000553687.1
ATP6V1D
ATPase, H+ transporting, lysosomal 34kDa, V1 subunit D
chr6_-_116447283 0.02 ENST00000452729.1
ENST00000243222.4
COL10A1
collagen, type X, alpha 1
chr17_-_73178599 0.01 ENST00000578238.1
SUMO2
small ubiquitin-like modifier 2
chr8_+_110656344 0.01 ENST00000499579.1
RP11-422N16.3
Uncharacterized protein

Network of associatons between targets according to the STRING database.

First level regulatory network of HLF_TEF

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0002384 hepatic immune response(GO:0002384)
0.2 1.6 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.9 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.1 0.2 GO:0035750 protein localization to myelin sheath abaxonal region(GO:0035750)
0.1 0.4 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.1 0.2 GO:1903565 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.2 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.2 GO:0032571 response to vitamin K(GO:0032571)
0.0 0.3 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.2 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 0.1 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.1 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979) regulation of cyclic nucleotide-gated ion channel activity(GO:1902159)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.7 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.5 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.2 GO:1901314 negative regulation of histone ubiquitination(GO:0033183) progesterone receptor signaling pathway(GO:0050847) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.2 GO:0071725 toll-like receptor TLR1:TLR2 signaling pathway(GO:0038123) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 0.0 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.0 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.1 GO:0035610 protein side chain deglutamylation(GO:0035610)
0.0 0.2 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.0 0.0 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.0 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.2 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.3 GO:0006999 nuclear pore organization(GO:0006999)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 1.6 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.1 0.2 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.4 GO:0043219 lateral loop(GO:0043219)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.5 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.1 0.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 1.6 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.2 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.0 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.2 GO:0016933 inhibitory extracellular ligand-gated ion channel activity(GO:0005237) extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0016019 peptidoglycan receptor activity(GO:0016019)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.5 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.2 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0048039 ubiquinone binding(GO:0048039)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 ST STAT3 PATHWAY STAT3 Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network