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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for HBP1

Z-value: 1.02

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Transcription factors associated with HBP1

Gene Symbol Gene ID Gene Info
HBP1
ENSG00000105856.9 HMG-box transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
HBP1hg19_v2_chr7_+_106809406_106809460-0.394.4e-01Click!

Activity profile of HBP1 motif

Sorted Z-values of HBP1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_125985620 0.88 ENST00000511512.1
ENST00000512435.1
RP11-71E19.1
RP11-71E19.1
chr19_-_6690723 0.74 ENST00000601008.1
C3
complement component 3
chr11_+_69061594 0.69 ENST00000441339.2
ENST00000308946.3
ENST00000535407.1
MYEOV
myeloma overexpressed
chr6_-_133035185 0.51 ENST00000367928.4
VNN1
vanin 1
chr5_+_159656437 0.49 ENST00000402432.3
FABP6
fatty acid binding protein 6, ileal
chr19_-_6057282 0.42 ENST00000592281.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr2_-_113594279 0.42 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr11_-_7698453 0.41 ENST00000524608.1
CYB5R2
cytochrome b5 reductase 2
chr18_+_61564389 0.38 ENST00000397996.2
ENST00000418725.1
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr19_+_49055332 0.36 ENST00000201586.2
SULT2B1
sulfotransferase family, cytosolic, 2B, member 1
chr12_-_89746264 0.36 ENST00000548755.1
DUSP6
dual specificity phosphatase 6
chr15_-_86338134 0.34 ENST00000337975.5
KLHL25
kelch-like family member 25
chr4_-_186696561 0.31 ENST00000445115.1
ENST00000451701.1
ENST00000457247.1
ENST00000435480.1
ENST00000425679.1
ENST00000457934.1
SORBS2
sorbin and SH3 domain containing 2
chr1_-_25291475 0.30 ENST00000338888.3
ENST00000399916.1
RUNX3
runt-related transcription factor 3
chr3_-_54962100 0.30 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr16_+_69140122 0.30 ENST00000219322.3
HAS3
hyaluronan synthase 3
chr17_-_4710288 0.30 ENST00000571067.1
RP11-81A22.5
RP11-81A22.5
chr11_+_123430948 0.29 ENST00000529432.1
ENST00000534764.1
GRAMD1B
GRAM domain containing 1B
chr19_-_6333614 0.28 ENST00000301452.4
ACER1
alkaline ceramidase 1
chr3_-_52090461 0.27 ENST00000296483.6
ENST00000495880.1
DUSP7
dual specificity phosphatase 7
chr22_-_50708781 0.26 ENST00000449719.2
ENST00000330651.6
MAPK11
mitogen-activated protein kinase 11
chr7_-_2354099 0.26 ENST00000222990.3
SNX8
sorting nexin 8
chr17_+_6918093 0.25 ENST00000439424.2
C17orf49
chromosome 17 open reading frame 49
chr16_-_30905584 0.25 ENST00000380317.4
BCL7C
B-cell CLL/lymphoma 7C
chr1_-_26680570 0.25 ENST00000475866.2
AIM1L
absent in melanoma 1-like
chr22_-_18256742 0.25 ENST00000317361.7
BID
BH3 interacting domain death agonist
chr19_+_34856078 0.25 ENST00000589399.1
ENST00000589640.1
ENST00000591204.1
GPI
glucose-6-phosphate isomerase
chr6_+_135818907 0.25 ENST00000579339.1
ENST00000580741.1
LINC00271
long intergenic non-protein coding RNA 271
chr10_+_24528108 0.25 ENST00000438429.1
KIAA1217
KIAA1217
chr3_+_98216448 0.25 ENST00000427338.1
OR5K2
olfactory receptor, family 5, subfamily K, member 2
chr3_+_133524459 0.25 ENST00000484684.1
SRPRB
signal recognition particle receptor, B subunit
chr1_+_113392455 0.25 ENST00000456651.1
ENST00000422022.1
RP3-522D1.1
RP3-522D1.1
chr11_-_65667884 0.24 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr5_-_140070897 0.24 ENST00000448240.1
ENST00000438307.2
ENST00000415192.2
ENST00000457527.2
ENST00000307633.3
ENST00000507746.1
ENST00000431330.2
HARS
histidyl-tRNA synthetase
chr7_+_65540780 0.24 ENST00000304874.9
ASL
argininosuccinate lyase
chr10_+_104180580 0.24 ENST00000425536.1
FBXL15
F-box and leucine-rich repeat protein 15
chr9_-_127624194 0.24 ENST00000373570.4
ENST00000348462.3
RPL35
ribosomal protein L35
chr20_+_31755934 0.23 ENST00000354932.5
BPIFA2
BPI fold containing family A, member 2
chr15_+_57884086 0.23 ENST00000380569.2
ENST00000380561.2
ENST00000574161.1
ENST00000572390.1
ENST00000396180.1
ENST00000380560.2
GCOM1
GRINL1A complex locus 1
chr7_+_65540853 0.23 ENST00000380839.4
ENST00000395332.3
ENST00000362000.5
ENST00000395331.3
ASL
argininosuccinate lyase
chr16_+_57769635 0.23 ENST00000379661.3
ENST00000562592.1
ENST00000566726.1
KATNB1
katanin p80 (WD repeat containing) subunit B 1
chrX_+_150151752 0.22 ENST00000325307.7
HMGB3
high mobility group box 3
chr1_-_53163992 0.22 ENST00000371538.3
SELRC1
cytochrome c oxidase assembly factor 7
chr19_-_38746979 0.22 ENST00000591291.1
PPP1R14A
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr17_-_39165366 0.21 ENST00000391588.1
KRTAP3-1
keratin associated protein 3-1
chr6_-_44233361 0.21 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr19_+_19144384 0.21 ENST00000392335.2
ENST00000535612.1
ENST00000537263.1
ENST00000540707.1
ENST00000541725.1
ENST00000269932.6
ENST00000546344.1
ENST00000540792.1
ENST00000536098.1
ENST00000541898.1
ENST00000543877.1
ARMC6
armadillo repeat containing 6
chr1_+_65730385 0.20 ENST00000263441.7
ENST00000395325.3
DNAJC6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr19_-_13213662 0.20 ENST00000264824.4
LYL1
lymphoblastic leukemia derived sequence 1
chr1_-_27693349 0.20 ENST00000374040.3
ENST00000357582.2
ENST00000493901.1
MAP3K6
mitogen-activated protein kinase kinase kinase 6
chr11_+_73087309 0.20 ENST00000064780.2
ENST00000545687.1
RELT
RELT tumor necrosis factor receptor
chr3_+_184032419 0.20 ENST00000352767.3
ENST00000427141.2
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr1_-_17338267 0.20 ENST00000326735.8
ATP13A2
ATPase type 13A2
chr11_-_65667997 0.19 ENST00000312562.2
ENST00000534222.1
FOSL1
FOS-like antigen 1
chr5_-_66942617 0.19 ENST00000507298.1
RP11-83M16.5
RP11-83M16.5
chr22_-_22337154 0.19 ENST00000413067.2
ENST00000437929.1
ENST00000456075.1
ENST00000434517.1
ENST00000424393.1
ENST00000449704.1
ENST00000437103.1
TOP3B
topoisomerase (DNA) III beta
chr15_-_40633101 0.19 ENST00000559313.1
C15orf52
chromosome 15 open reading frame 52
chr2_-_220264703 0.19 ENST00000519905.1
ENST00000523282.1
ENST00000434339.1
ENST00000457935.1
DNPEP
aspartyl aminopeptidase
chr19_+_1040096 0.19 ENST00000263094.6
ENST00000524850.1
ABCA7
ATP-binding cassette, sub-family A (ABC1), member 7
chrX_+_18725758 0.19 ENST00000472826.1
ENST00000544635.1
ENST00000496075.2
PPEF1
protein phosphatase, EF-hand calcium binding domain 1
chr16_-_82203780 0.19 ENST00000563504.1
ENST00000569021.1
ENST00000258169.4
MPHOSPH6
M-phase phosphoprotein 6
chr7_-_5821314 0.18 ENST00000425013.2
ENST00000389902.3
RNF216
ring finger protein 216
chr15_+_75074410 0.18 ENST00000439220.2
CSK
c-src tyrosine kinase
chr4_-_119757239 0.18 ENST00000280551.6
SEC24D
SEC24 family member D
chr3_+_184032283 0.18 ENST00000346169.2
ENST00000414031.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr19_+_34855925 0.18 ENST00000590375.1
ENST00000356487.5
GPI
glucose-6-phosphate isomerase
chr2_-_157189180 0.18 ENST00000539077.1
ENST00000424077.1
ENST00000426264.1
ENST00000339562.4
ENST00000421709.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr4_+_6202448 0.17 ENST00000508601.1
RP11-586D19.1
RP11-586D19.1
chr11_+_6947720 0.17 ENST00000414517.2
ZNF215
zinc finger protein 215
chr6_-_30640811 0.17 ENST00000376442.3
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr4_-_119757322 0.17 ENST00000379735.5
SEC24D
SEC24 family member D
chr2_+_74425689 0.17 ENST00000394053.2
ENST00000409804.1
ENST00000264090.4
ENST00000394050.3
ENST00000409601.1
MTHFD2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
chr3_-_127455200 0.17 ENST00000398101.3
MGLL
monoglyceride lipase
chr3_+_184032313 0.17 ENST00000392537.2
ENST00000444134.1
ENST00000450424.1
ENST00000421110.1
ENST00000382330.3
ENST00000426123.1
ENST00000350481.5
ENST00000455679.1
ENST00000440448.1
EIF4G1
eukaryotic translation initiation factor 4 gamma, 1
chr18_+_52385068 0.17 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr6_+_117803797 0.16 ENST00000296955.8
ENST00000368503.4
ENST00000338728.5
DCBLD1
discoidin, CUB and LCCL domain containing 1
chr20_-_33872548 0.16 ENST00000374443.3
EIF6
eukaryotic translation initiation factor 6
chr9_-_35563896 0.16 ENST00000399742.2
FAM166B
family with sequence similarity 166, member B
chr13_-_46626820 0.16 ENST00000428921.1
ZC3H13
zinc finger CCCH-type containing 13
chr14_+_102430855 0.15 ENST00000360184.4
DYNC1H1
dynein, cytoplasmic 1, heavy chain 1
chr9_-_128246769 0.15 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr19_+_34856141 0.15 ENST00000586425.1
GPI
glucose-6-phosphate isomerase
chr22_+_41968007 0.15 ENST00000460790.1
CSDC2
cold shock domain containing C2, RNA binding
chr20_+_25176450 0.15 ENST00000425813.1
ENTPD6
ectonucleoside triphosphate diphosphohydrolase 6 (putative)
chr5_+_140514782 0.15 ENST00000231134.5
PCDHB5
protocadherin beta 5
chr19_-_18508396 0.15 ENST00000595840.1
ENST00000339007.3
LRRC25
leucine rich repeat containing 25
chr19_-_10305752 0.15 ENST00000540357.1
ENST00000359526.4
ENST00000340748.4
DNMT1
DNA (cytosine-5-)-methyltransferase 1
chr1_-_151319654 0.15 ENST00000430227.1
ENST00000412774.1
RFX5
regulatory factor X, 5 (influences HLA class II expression)
chr15_+_57884117 0.15 ENST00000267853.5
MYZAP
myocardial zonula adherens protein
chr19_-_3500635 0.15 ENST00000250937.3
DOHH
deoxyhypusine hydroxylase/monooxygenase
chrX_+_100075368 0.15 ENST00000415585.2
ENST00000372972.2
ENST00000413437.1
CSTF2
cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa
chr17_+_33895090 0.14 ENST00000592381.1
RP11-1094M14.11
RP11-1094M14.11
chr19_-_10697895 0.14 ENST00000591240.1
ENST00000589684.1
ENST00000591676.1
ENST00000250244.6
ENST00000590923.1
AP1M2
adaptor-related protein complex 1, mu 2 subunit
chr19_+_17830051 0.14 ENST00000594625.1
ENST00000324096.4
ENST00000600186.1
ENST00000597735.1
MAP1S
microtubule-associated protein 1S
chr12_+_57984943 0.14 ENST00000422156.3
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr14_+_32963433 0.14 ENST00000554410.1
AKAP6
A kinase (PRKA) anchor protein 6
chr16_+_77756399 0.13 ENST00000564085.1
ENST00000268533.5
ENST00000568787.1
ENST00000437314.3
ENST00000563839.1
NUDT7
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr14_-_101053739 0.13 ENST00000554140.1
BEGAIN
brain-enriched guanylate kinase-associated
chr9_+_116207007 0.13 ENST00000374140.2
RGS3
regulator of G-protein signaling 3
chr16_+_77246337 0.13 ENST00000563157.1
SYCE1L
synaptonemal complex central element protein 1-like
chr11_-_68611721 0.13 ENST00000561996.1
CPT1A
carnitine palmitoyltransferase 1A (liver)
chr12_+_57984965 0.13 ENST00000540759.2
ENST00000551772.1
ENST00000550465.1
ENST00000354947.5
PIP4K2C
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr12_-_12714025 0.13 ENST00000539940.1
DUSP16
dual specificity phosphatase 16
chr10_+_13203543 0.13 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
MCM10
minichromosome maintenance complex component 10
chr17_-_42327236 0.13 ENST00000399246.2
AC003102.1
AC003102.1
chr1_-_113392399 0.13 ENST00000449572.2
ENST00000433505.1
RP11-426L16.8
RP11-426L16.8
chr2_-_74375081 0.13 ENST00000327428.5
BOLA3
bolA family member 3
chr5_+_175223313 0.12 ENST00000359546.4
CPLX2
complexin 2
chr4_-_186697044 0.12 ENST00000437304.2
SORBS2
sorbin and SH3 domain containing 2
chr10_-_120101804 0.12 ENST00000369183.4
ENST00000369172.4
FAM204A
family with sequence similarity 204, member A
chr1_-_24126892 0.12 ENST00000374497.3
ENST00000425913.1
GALE
UDP-galactose-4-epimerase
chr10_+_82300575 0.12 ENST00000313455.4
SH2D4B
SH2 domain containing 4B
chr6_+_30297306 0.12 ENST00000420746.1
ENST00000513556.1
TRIM39
TRIM39-RPP21
tripartite motif containing 39
TRIM39-RPP21 readthrough
chr19_+_41698927 0.12 ENST00000310054.4
CYP2S1
cytochrome P450, family 2, subfamily S, polypeptide 1
chr19_-_42806444 0.12 ENST00000594989.1
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr9_+_133589333 0.12 ENST00000372348.2
ENST00000393293.4
ABL1
c-abl oncogene 1, non-receptor tyrosine kinase
chr15_+_75074385 0.12 ENST00000220003.9
CSK
c-src tyrosine kinase
chr6_-_41909561 0.12 ENST00000372991.4
CCND3
cyclin D3
chr19_+_17326521 0.12 ENST00000593597.1
USE1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr11_-_66725837 0.11 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC
pyruvate carboxylase
chr1_+_200860122 0.11 ENST00000532631.1
ENST00000451872.2
C1orf106
chromosome 1 open reading frame 106
chr12_-_110271178 0.11 ENST00000261740.2
ENST00000392719.2
ENST00000346520.2
TRPV4
transient receptor potential cation channel, subfamily V, member 4
chr5_-_16465901 0.11 ENST00000308683.2
ZNF622
zinc finger protein 622
chr17_+_75369400 0.11 ENST00000590059.1
SEPT9
septin 9
chr3_+_46616017 0.11 ENST00000542931.1
TDGF1
teratocarcinoma-derived growth factor 1
chr7_+_99070527 0.11 ENST00000379724.3
ZNF789
zinc finger protein 789
chr7_-_130080977 0.11 ENST00000223208.5
CEP41
centrosomal protein 41kDa
chr1_-_24127256 0.11 ENST00000418277.1
GALE
UDP-galactose-4-epimerase
chr5_+_125758813 0.11 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr3_+_126423045 0.11 ENST00000290913.3
ENST00000508789.1
CHCHD6
coiled-coil-helix-coiled-coil-helix domain containing 6
chr17_+_68071458 0.11 ENST00000589377.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr1_-_154155675 0.11 ENST00000330188.9
ENST00000341485.5
TPM3
tropomyosin 3
chr2_+_242498135 0.11 ENST00000318407.3
BOK
BCL2-related ovarian killer
chr18_-_56985776 0.10 ENST00000587244.1
CPLX4
complexin 4
chr12_+_123868320 0.10 ENST00000402868.3
ENST00000330479.4
SETD8
SET domain containing (lysine methyltransferase) 8
chrX_+_150151824 0.10 ENST00000455596.1
ENST00000448905.2
HMGB3
high mobility group box 3
chr1_+_25598872 0.10 ENST00000328664.4
RHD
Rh blood group, D antigen
chr3_+_111805262 0.10 ENST00000484828.1
C3orf52
chromosome 3 open reading frame 52
chr3_+_140770183 0.10 ENST00000310546.2
SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr12_-_11139511 0.10 ENST00000506868.1
TAS2R50
taste receptor, type 2, member 50
chr20_-_48747662 0.10 ENST00000371656.2
TMEM189
transmembrane protein 189
chr7_+_18536090 0.10 ENST00000441986.1
HDAC9
histone deacetylase 9
chr9_-_34665983 0.10 ENST00000416454.1
ENST00000544078.2
ENST00000421828.2
ENST00000423809.1
RP11-195F19.5
HCG2040265, isoform CRA_a; Uncharacterized protein; cDNA FLJ50015
chr19_+_3506261 0.10 ENST00000441788.2
FZR1
fizzy/cell division cycle 20 related 1 (Drosophila)
chr12_-_53320245 0.10 ENST00000552150.1
KRT8
keratin 8
chr22_+_39745930 0.10 ENST00000318801.4
ENST00000216155.7
ENST00000406293.3
ENST00000328933.5
SYNGR1
synaptogyrin 1
chrX_+_54834159 0.10 ENST00000375053.2
ENST00000347546.4
ENST00000375062.4
MAGED2
melanoma antigen family D, 2
chr8_-_128231299 0.09 ENST00000500112.1
CCAT1
colon cancer associated transcript 1 (non-protein coding)
chr15_-_93965805 0.09 ENST00000556708.1
RP11-164C12.2
RP11-164C12.2
chr19_+_34855874 0.09 ENST00000588991.2
GPI
glucose-6-phosphate isomerase
chr9_-_25678856 0.09 ENST00000358022.3
TUSC1
tumor suppressor candidate 1
chr7_+_18535854 0.09 ENST00000401921.1
HDAC9
histone deacetylase 9
chr17_+_49230897 0.09 ENST00000393196.3
ENST00000336097.3
ENST00000480143.1
ENST00000511355.1
ENST00000013034.3
ENST00000393198.3
ENST00000608447.1
ENST00000393193.2
ENST00000376392.6
ENST00000555572.1
NME1
NME1-NME2
NME2
NME/NM23 nucleoside diphosphate kinase 1
NME1-NME2 readthrough
NME/NM23 nucleoside diphosphate kinase 2
chr20_+_30458431 0.09 ENST00000375938.4
ENST00000535842.1
ENST00000310998.4
ENST00000375921.2
TTLL9
tubulin tyrosine ligase-like family, member 9
chr19_-_42806919 0.09 ENST00000595530.1
ENST00000538771.1
ENST00000601865.1
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr17_+_68071389 0.09 ENST00000283936.1
ENST00000392671.1
KCNJ16
potassium inwardly-rectifying channel, subfamily J, member 16
chr8_-_11725549 0.09 ENST00000505496.2
ENST00000534636.1
ENST00000524500.1
ENST00000345125.3
ENST00000453527.2
ENST00000527215.2
ENST00000532392.1
ENST00000533455.1
ENST00000534510.1
ENST00000530640.2
ENST00000531089.1
ENST00000532656.2
ENST00000531502.1
ENST00000434271.1
ENST00000353047.6
CTSB
cathepsin B
chr3_-_178103144 0.09 ENST00000417383.1
ENST00000418585.1
ENST00000411727.1
ENST00000439810.1
RP11-33A14.1
RP11-33A14.1
chr1_+_66797687 0.09 ENST00000371045.5
ENST00000531025.1
ENST00000526197.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr4_-_186696515 0.09 ENST00000456596.1
ENST00000414724.1
SORBS2
sorbin and SH3 domain containing 2
chr7_-_92777606 0.09 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr20_+_25176318 0.09 ENST00000354989.5
ENST00000360031.2
ENST00000376652.4
ENST00000439162.1
ENST00000433417.1
ENST00000417467.1
ENST00000433259.2
ENST00000427553.1
ENST00000435520.1
ENST00000418890.1
ENTPD6
ectonucleoside triphosphate diphosphohydrolase 6 (putative)
chr15_+_57891609 0.09 ENST00000569089.1
MYZAP
myocardial zonula adherens protein
chr19_-_42806723 0.09 ENST00000262890.3
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chr16_-_28223166 0.08 ENST00000304658.5
XPO6
exportin 6
chrX_+_54834004 0.08 ENST00000375068.1
MAGED2
melanoma antigen family D, 2
chr13_+_88325498 0.08 ENST00000400028.3
SLITRK5
SLIT and NTRK-like family, member 5
chr16_+_30953696 0.08 ENST00000566320.2
ENST00000565939.1
FBXL19
F-box and leucine-rich repeat protein 19
chr20_-_56286479 0.08 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr7_+_18535893 0.08 ENST00000432645.2
ENST00000441542.2
HDAC9
histone deacetylase 9
chr8_+_104152922 0.08 ENST00000309982.5
ENST00000438105.2
ENST00000297574.6
BAALC
brain and acute leukemia, cytoplasmic
chr15_-_65407524 0.08 ENST00000559089.1
UBAP1L
ubiquitin associated protein 1-like
chr20_-_33872518 0.08 ENST00000374436.3
EIF6
eukaryotic translation initiation factor 6
chr8_+_63161550 0.08 ENST00000328472.5
NKAIN3
Na+/K+ transporting ATPase interacting 3
chr5_+_140071011 0.08 ENST00000230771.3
ENST00000509299.1
ENST00000503873.1
ENST00000435019.2
ENST00000437649.2
ENST00000432671.2
HARS2
histidyl-tRNA synthetase 2, mitochondrial
chr12_+_1099675 0.08 ENST00000545318.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr1_+_44435646 0.08 ENST00000255108.3
ENST00000412950.2
ENST00000396758.2
DPH2
DPH2 homolog (S. cerevisiae)
chr1_-_154155595 0.08 ENST00000328159.4
ENST00000368531.2
ENST00000323144.7
ENST00000368533.3
ENST00000341372.3
TPM3
tropomyosin 3
chr1_-_31769595 0.08 ENST00000263694.4
SNRNP40
small nuclear ribonucleoprotein 40kDa (U5)
chr12_-_93835665 0.08 ENST00000552442.1
ENST00000550657.1
UBE2N
ubiquitin-conjugating enzyme E2N
chr9_-_113800705 0.08 ENST00000441240.1
LPAR1
lysophosphatidic acid receptor 1
chr7_+_6617039 0.08 ENST00000405731.3
ENST00000396713.2
ENST00000396707.2
ENST00000335965.6
ENST00000396709.1
ENST00000483589.1
ENST00000396706.2
ZDHHC4
zinc finger, DHHC-type containing 4
chr20_-_39928705 0.07 ENST00000436099.2
ENST00000309060.3
ENST00000373261.1
ENST00000436440.2
ENST00000540170.1
ENST00000557816.1
ENST00000560361.1
ZHX3
zinc fingers and homeoboxes 3
chr5_+_150040403 0.07 ENST00000517768.1
ENST00000297130.4
MYOZ3
myozenin 3
chr9_+_78505554 0.07 ENST00000545128.1
PCSK5
proprotein convertase subtilisin/kexin type 5
chr10_+_104263743 0.07 ENST00000369902.3
ENST00000369899.2
ENST00000423559.2
SUFU
suppressor of fused homolog (Drosophila)
chr7_-_149158187 0.07 ENST00000247930.4
ZNF777
zinc finger protein 777
chr6_+_10521574 0.07 ENST00000495262.1
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr20_+_13765596 0.07 ENST00000378106.5
ENST00000463598.1
NDUFAF5
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
chr5_-_22853429 0.07 ENST00000504376.2
CDH12
cadherin 12, type 2 (N-cadherin 2)
chr6_-_30640761 0.07 ENST00000415603.1
DHX16
DEAH (Asp-Glu-Ala-His) box polypeptide 16
chr3_+_37441062 0.07 ENST00000426078.1
C3orf35
chromosome 3 open reading frame 35
chr4_-_186682716 0.07 ENST00000445343.1
SORBS2
sorbin and SH3 domain containing 2
chr2_+_231902193 0.07 ENST00000373640.4
C2orf72
chromosome 2 open reading frame 72
chr3_+_186288454 0.07 ENST00000265028.3
DNAJB11
DnaJ (Hsp40) homolog, subfamily B, member 11
chr8_-_69243711 0.07 ENST00000512294.3
RP11-664D7.4
HCG1787533; Uncharacterized protein
chr2_-_40739501 0.07 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
SLC8A1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr18_-_68004529 0.07 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr22_-_20368028 0.07 ENST00000404912.1
GGTLC3
gamma-glutamyltransferase light chain 3
chr11_+_22689648 0.07 ENST00000278187.3
GAS2
growth arrest-specific 2

Network of associatons between targets according to the STRING database.

First level regulatory network of HBP1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.1 0.7 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.1 0.3 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.1 0.4 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.3 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.3 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.2 GO:1904351 negative regulation of protein catabolic process in the vacuole(GO:1904351) negative regulation of lysosomal protein catabolic process(GO:1905166)
0.1 0.2 GO:1901076 positive regulation of engulfment of apoptotic cell(GO:1901076)
0.1 0.4 GO:0031622 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.1 0.2 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.5 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.3 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.2 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0046356 acetyl-CoA catabolic process(GO:0046356)
0.0 0.3 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.1 GO:1990051 activation of protein kinase C activity(GO:1990051)
0.0 0.1 GO:2000338 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338) positive regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000340)
0.0 0.1 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:0045209 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.0 0.5 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.2 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 0.1 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.2 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.2 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:1901382 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.2 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.0 0.2 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.1 GO:0090116 DNA methylation on cytosine(GO:0032776) C-5 methylation of cytosine(GO:0090116)
0.0 0.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.3 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.3 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.5 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.0 GO:0000706 meiotic DNA double-strand break processing(GO:0000706)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.6 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.3 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.2 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.0 0.3 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.0 0.1 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.3 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0036117 hyaluranon cable(GO:0036117)
0.0 0.2 GO:0031166 integral component of vacuolar membrane(GO:0031166)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.0 0.5 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0036021 endolysosome lumen(GO:0036021)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.0 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.2 GO:0042589 platelet dense granule membrane(GO:0031088) zymogen granule membrane(GO:0042589)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.1 0.3 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 0.5 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.1 0.3 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.2 GO:0003978 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.1 0.2 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 0.4 GO:0050294 steroid sulfotransferase activity(GO:0050294)
0.0 0.3 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.5 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.5 GO:0032052 bile acid binding(GO:0032052)
0.0 0.2 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.0 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.3 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.5 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0008478 pyridoxal kinase activity(GO:0008478)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.1 GO:0031433 telethonin binding(GO:0031433)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.0 GO:0016499 orexin receptor activity(GO:0016499)
0.0 0.0 GO:0048257 3'-flap endonuclease activity(GO:0048257)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.1 GO:0004515 nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.6 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.2 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.0 GO:0008466 glycogenin glucosyltransferase activity(GO:0008466)
0.0 0.1 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.3 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains