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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GUGCAAA

Z-value: 0.98

Motif logo

miRNA associated with seed GUGCAAA

NamemiRBASE accession
MIMAT0000073
MIMAT0000074

Activity profile of GUGCAAA motif

Sorted Z-values of GUGCAAA motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_135056216 0.62 ENST00000305963.2
membrane magnesium transporter 1
chr1_-_70671216 0.57 ENST00000370952.3
leucine rich repeat containing 40
chr18_+_9136758 0.51 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ankyrin repeat domain 12
chr12_+_69004619 0.51 ENST00000250559.9
ENST00000393436.5
ENST00000425247.2
ENST00000489473.2
ENST00000422358.2
ENST00000541167.1
ENST00000538283.1
ENST00000341355.5
ENST00000537460.1
ENST00000450214.2
ENST00000545270.1
ENST00000538980.1
ENST00000542018.1
ENST00000543393.1
RAP1B, member of RAS oncogene family
chr6_-_46138676 0.51 ENST00000371383.2
ENST00000230565.3
ectonucleotide pyrophosphatase/phosphodiesterase 5 (putative)
chr1_-_244615425 0.48 ENST00000366535.3
adenylosuccinate synthase
chr2_+_189156389 0.43 ENST00000409843.1
GULP, engulfment adaptor PTB domain containing 1
chr7_+_23636992 0.43 ENST00000307471.3
ENST00000409765.1
coiled-coil domain containing 126
chr6_+_16129308 0.42 ENST00000356840.3
ENST00000349606.4
myosin regulatory light chain interacting protein
chr14_-_57735528 0.38 ENST00000340918.7
ENST00000413566.2
exocyst complex component 5
chr11_-_94964354 0.37 ENST00000536441.1
sestrin 3
chr20_+_47662805 0.37 ENST00000262982.2
ENST00000542325.1
CSE1 chromosome segregation 1-like (yeast)
chr2_+_20646824 0.36 ENST00000272233.4
ras homolog family member B
chr13_-_27745936 0.34 ENST00000282344.6
ubiquitin specific peptidase 12
chr15_+_98503922 0.33 ENST00000268042.6
arrestin domain containing 4
chr14_-_64010046 0.33 ENST00000337537.3
protein phosphatase 2, regulatory subunit B', epsilon isoform
chr4_-_76598296 0.33 ENST00000395719.3
GTPase activating protein (SH3 domain) binding protein 2
chr1_-_67519782 0.33 ENST00000235345.5
solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
chr4_+_85504075 0.33 ENST00000295887.5
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr6_-_109703663 0.33 ENST00000368961.5
CD164 molecule, sialomucin
chr1_+_52521928 0.33 ENST00000489308.2
basic transcription factor 3-like 4
chr13_+_97874574 0.33 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
muscleblind-like splicing regulator 2
chr2_-_122042770 0.33 ENST00000263707.5
transcription factor CP2-like 1
chr4_-_100867864 0.32 ENST00000442697.2
DnaJ (Hsp40) homolog, subfamily B, member 14
chr4_-_175205407 0.32 ENST00000393674.2
F-box protein 8
chr6_+_89790490 0.31 ENST00000336032.3
proline-rich nuclear receptor coactivator 1
chr10_+_89622870 0.31 ENST00000371953.3
phosphatase and tensin homolog
chr10_+_112404132 0.31 ENST00000369519.3
RNA binding motif protein 20
chr14_+_60715928 0.30 ENST00000395076.4
protein phosphatase, Mg2+/Mn2+ dependent, 1A
chr15_-_52861394 0.30 ENST00000563277.1
ENST00000566423.1
cAMP-regulated phosphoprotein, 19kDa
chr8_+_59323823 0.30 ENST00000399598.2
UBX domain protein 2B
chr2_+_219745020 0.30 ENST00000258411.3
wingless-type MMTV integration site family, member 10A
chr11_+_120894781 0.29 ENST00000529397.1
ENST00000528512.1
ENST00000422003.2
tubulin folding cofactor E-like
chrX_-_131352152 0.29 ENST00000342983.2
RAP2C, member of RAS oncogene family
chr2_-_101767715 0.28 ENST00000376840.4
ENST00000409318.1
TBC1 domain family, member 8 (with GRAM domain)
chr3_+_57261743 0.28 ENST00000288266.3
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr1_+_26438289 0.28 ENST00000374271.4
ENST00000374269.1
PDLIM1 interacting kinase 1 like
chr8_-_12612962 0.27 ENST00000398246.3
LON peptidase N-terminal domain and ring finger 1
chr12_+_67663056 0.27 ENST00000545606.1
cullin-associated and neddylation-dissociated 1
chr3_-_138553594 0.27 ENST00000477593.1
ENST00000483968.1
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta
chr21_-_40685477 0.27 ENST00000342449.3
bromodomain and WD repeat domain containing 1
chr9_+_19408999 0.27 ENST00000340967.2
alkaline ceramidase 2
chr10_+_23728198 0.27 ENST00000376495.3
OTU domain containing 1
chr1_-_93426998 0.26 ENST00000370310.4
family with sequence similarity 69, member A
chr17_-_48072574 0.25 ENST00000434704.2
distal-less homeobox 3
chr13_-_30424821 0.25 ENST00000380680.4
ubiquitin-like 3
chr1_+_162467595 0.25 ENST00000538489.1
ENST00000489294.1
U2AF homology motif (UHM) kinase 1
chr11_-_117186946 0.25 ENST00000313005.6
ENST00000528053.1
beta-site APP-cleaving enzyme 1
chr4_-_120550146 0.24 ENST00000354960.3
phosphodiesterase 5A, cGMP-specific
chr4_-_36246060 0.24 ENST00000303965.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr3_-_178790057 0.24 ENST00000311417.2
zinc finger, matrin-type 3
chr15_+_80987617 0.24 ENST00000258884.4
ENST00000558464.1
abhydrolase domain containing 17C
chr3_+_152017181 0.24 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
muscleblind-like splicing regulator 1
chr1_-_169337176 0.24 ENST00000472647.1
ENST00000367811.3
NME/NM23 family member 7
chr6_-_132272504 0.23 ENST00000367976.3
connective tissue growth factor
chr10_+_111767720 0.23 ENST00000356080.4
ENST00000277900.8
adducin 3 (gamma)
chr4_+_75174180 0.23 ENST00000413830.1
epithelial mitogen
chr5_+_138940742 0.23 ENST00000398733.3
ENST00000253815.2
ENST00000505007.1
ubiquitin-conjugating enzyme E2D 2
chr22_+_40390930 0.23 ENST00000333407.6
family with sequence similarity 83, member F
chr6_-_111136513 0.23 ENST00000368911.3
cyclin-dependent kinase 19
chr22_-_28197486 0.23 ENST00000302326.4
meningioma (disrupted in balanced translocation) 1
chr8_-_103876965 0.23 ENST00000337198.5
antizyme inhibitor 1
chr17_+_55333876 0.23 ENST00000284073.2
musashi RNA-binding protein 2
chr10_-_98346801 0.23 ENST00000371142.4
transmembrane 9 superfamily member 3
chr19_+_10527449 0.22 ENST00000592685.1
ENST00000380702.2
phosphodiesterase 4A, cAMP-specific
chr14_-_55878538 0.22 ENST00000247178.5
autophagy related 14
chr1_+_92495528 0.22 ENST00000370383.4
epoxide hydrolase 4
chr8_-_68255912 0.22 ENST00000262215.3
ENST00000519436.1
ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
chr9_-_6007787 0.22 ENST00000399933.3
ENST00000381461.2
ENST00000513355.2
KIAA2026
chr5_+_96271141 0.22 ENST00000231368.5
leucyl/cystinyl aminopeptidase
chr7_+_114562172 0.22 ENST00000393486.1
ENST00000257724.3
MyoD family inhibitor domain containing
chr2_+_46926048 0.22 ENST00000306503.5
suppressor of cytokine signaling 5
chr2_-_183903133 0.21 ENST00000361354.4
NCK-associated protein 1
chr7_-_79082867 0.21 ENST00000419488.1
ENST00000354212.4
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr13_+_80055284 0.21 ENST00000218652.7
Nedd4 family interacting protein 2
chr1_-_71546690 0.21 ENST00000254821.6
zinc finger, RAN-binding domain containing 2
chr8_+_104831472 0.21 ENST00000262231.10
ENST00000507740.1
regulating synaptic membrane exocytosis 2
chr1_+_212458834 0.21 ENST00000261461.2
protein phosphatase 2, regulatory subunit B', alpha
chr10_+_95256356 0.21 ENST00000371485.3
centrosomal protein 55kDa
chr3_-_182698381 0.21 ENST00000292782.4
DCN1, defective in cullin neddylation 1, domain containing 1
chr15_-_49338748 0.20 ENST00000559471.1
SECIS binding protein 2-like
chr4_+_128703295 0.20 ENST00000296464.4
ENST00000508549.1
heat shock 70kDa protein 4-like
chr1_-_46598284 0.19 ENST00000423209.1
ENST00000262741.5
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr20_+_19867150 0.19 ENST00000255006.6
Ras and Rab interactor 2
chr17_+_28705921 0.19 ENST00000225719.4
carboxypeptidase D
chrX_-_34675391 0.19 ENST00000275954.3
transmembrane protein 47
chr2_-_39664405 0.19 ENST00000341681.5
ENST00000263881.3
mitogen-activated protein kinase kinase kinase kinase 3
chr3_+_102153859 0.19 ENST00000306176.1
ENST00000466937.1
zona pellucida-like domain containing 1
chr10_-_118764862 0.19 ENST00000260777.10
KIAA1598
chr15_+_52311398 0.19 ENST00000261845.5
mitogen-activated protein kinase 6
chr4_+_41362796 0.19 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIM and calponin homology domains 1
chr5_-_136834982 0.19 ENST00000510689.1
ENST00000394945.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1
chr3_-_57678772 0.19 ENST00000311128.5
DENN/MADD domain containing 6A
chr1_+_101361626 0.19 ENST00000370112.4
solute carrier family 30 (zinc transporter), member 7
chr4_-_78740511 0.19 ENST00000504123.1
ENST00000264903.4
ENST00000515441.1
CCR4-NOT transcription complex, subunit 6-like
chr14_-_53619816 0.19 ENST00000323669.5
ENST00000395606.1
ENST00000357758.3
DDHD domain containing 1
chr5_+_95997918 0.19 ENST00000395812.2
ENST00000395813.1
ENST00000359176.4
ENST00000325674.7
calpastatin
chr5_-_1882858 0.18 ENST00000511126.1
ENST00000231357.2
iroquois homeobox 4
chr8_+_6565854 0.18 ENST00000285518.6
1-acylglycerol-3-phosphate O-acyltransferase 5
chr8_-_67525473 0.18 ENST00000522677.3
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr14_-_81687197 0.18 ENST00000553612.1
general transcription factor IIA, 1, 19/37kDa
chr12_-_111021110 0.18 ENST00000354300.3
PTC7 protein phosphatase homolog (S. cerevisiae)
chr15_+_78730531 0.18 ENST00000258886.8
iron-responsive element binding protein 2
chr1_+_57110972 0.18 ENST00000371244.4
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr11_+_107879459 0.18 ENST00000393094.2
cullin 5
chr10_-_61666267 0.18 ENST00000263102.6
coiled-coil domain containing 6
chr17_+_30264014 0.18 ENST00000322652.5
ENST00000580398.1
SUZ12 polycomb repressive complex 2 subunit
chr3_-_18466787 0.17 ENST00000338745.6
ENST00000450898.1
SATB homeobox 1
chr2_+_173292301 0.17 ENST00000264106.6
ENST00000375221.2
ENST00000343713.4
integrin, alpha 6
chr5_+_42423872 0.17 ENST00000230882.4
ENST00000357703.3
growth hormone receptor
chr3_+_178866199 0.17 ENST00000263967.3
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr18_-_51751132 0.17 ENST00000256429.3
methyl-CpG binding domain protein 2
chr8_-_110660999 0.17 ENST00000424158.2
ENST00000533895.1
ENST00000446070.2
ENST00000528331.1
ENST00000526302.1
ENST00000433638.1
ENST00000408908.2
ENST00000524720.1
syntabulin (syntaxin-interacting)
chrX_+_118708493 0.17 ENST00000371558.2
ubiquitin-conjugating enzyme E2A
chr12_+_64845660 0.16 ENST00000331710.5
TANK-binding kinase 1
chr9_-_99180597 0.16 ENST00000375256.4
zinc finger protein 367
chr18_-_65184217 0.16 ENST00000310045.7
dermatan sulfate epimerase-like
chr9_-_123964114 0.16 ENST00000373840.4
RAB14, member RAS oncogene family
chr2_+_64751433 0.16 ENST00000238856.4
ENST00000422803.1
ENST00000238855.7
aftiphilin
chr1_-_27339317 0.16 ENST00000289166.5
family with sequence similarity 46, member B
chr7_+_77469439 0.16 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
putative homeodomain transcription factor 2
chr6_-_116381918 0.16 ENST00000606080.1
fyn-related kinase
chr3_+_194406603 0.16 ENST00000329759.4
family with sequence similarity 43, member A
chr7_-_127032741 0.16 ENST00000393313.1
ENST00000265827.3
ENST00000434602.1
zinc finger protein 800
chr3_-_11762202 0.16 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
vestigial like 4 (Drosophila)
chr2_-_65357225 0.16 ENST00000398529.3
ENST00000409751.1
ENST00000356214.7
ENST00000409892.1
ENST00000409784.3
RAB1A, member RAS oncogene family
chr5_-_90679145 0.16 ENST00000265138.3
arrestin domain containing 3
chr1_+_51701924 0.16 ENST00000242719.3
ring finger protein 11
chr1_-_91487013 0.15 ENST00000347275.5
ENST00000370440.1
zinc finger protein 644
chr2_-_134326009 0.15 ENST00000409261.1
ENST00000409213.1
NCK-associated protein 5
chr8_-_95961578 0.15 ENST00000448464.2
ENST00000342697.4
tumor protein p53 inducible nuclear protein 1
chr1_+_178995021 0.15 ENST00000263733.4
family with sequence similarity 20, member B
chr1_-_78225482 0.15 ENST00000524778.1
ENST00000370794.3
ENST00000370793.1
ENST00000370792.3
ubiquitin specific peptidase 33
chr1_+_84543734 0.15 ENST00000370689.2
protein kinase, cAMP-dependent, catalytic, beta
chr7_-_112579869 0.15 ENST00000297145.4
chromosome 7 open reading frame 60
chr10_+_65281123 0.15 ENST00000298249.4
ENST00000373758.4
receptor accessory protein 3
chrX_+_135067576 0.15 ENST00000370701.1
ENST00000370698.3
ENST00000370695.4
solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6
chr6_-_79787902 0.15 ENST00000275034.4
pleckstrin homology domain interacting protein
chr12_-_22697343 0.15 ENST00000446597.1
ENST00000536386.1
ENST00000396028.2
ENST00000545552.1
ENST00000544930.1
ENST00000333957.4
C2 calcium-dependent domain containing 5
chr16_+_67063036 0.15 ENST00000290858.6
ENST00000564034.1
core-binding factor, beta subunit
chr20_-_5591626 0.15 ENST00000379019.4
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr9_-_140196703 0.15 ENST00000356628.2
NOTCH-regulated ankyrin repeat protein
chr19_+_41768401 0.14 ENST00000352456.3
ENST00000595018.1
ENST00000597725.1
heterogeneous nuclear ribonucleoprotein U-like 1
chr3_+_122513642 0.14 ENST00000261038.5
disrupted in renal carcinoma 2
chr6_+_25279651 0.14 ENST00000329474.6
leucine rich repeat containing 16A
chr1_-_222885770 0.14 ENST00000355727.2
ENST00000340020.6
axin interactor, dorsalization associated
chr10_-_60027642 0.14 ENST00000373935.3
inositol polyphosphate multikinase
chr3_+_29322803 0.14 ENST00000396583.3
ENST00000383767.2
RNA binding motif, single stranded interacting protein 3
chr16_-_46655538 0.14 ENST00000303383.3
SHC SH2-domain binding protein 1
chrX_+_72783026 0.14 ENST00000373504.6
ENST00000373502.5
cysteine-rich hydrophobic domain 1
chr2_-_201936302 0.14 ENST00000453765.1
ENST00000452799.1
ENST00000446678.1
ENST00000418596.3
family with sequence similarity 126, member B
chr15_+_63481668 0.14 ENST00000321437.4
ENST00000559006.1
ENST00000448330.2
RAB8B, member RAS oncogene family
chr4_-_170924888 0.14 ENST00000502832.1
ENST00000393704.3
microfibrillar-associated protein 3-like
chr14_+_37667118 0.13 ENST00000556615.1
ENST00000327441.7
ENST00000536774.1
mirror-image polydactyly 1
chr20_-_52210368 0.13 ENST00000371471.2
zinc finger protein 217
chrX_-_108976521 0.13 ENST00000469796.2
ENST00000502391.1
ENST00000508092.1
ENST00000340800.2
ENST00000348502.6
acyl-CoA synthetase long-chain family member 4
chr4_+_166248775 0.13 ENST00000261507.6
ENST00000507013.1
ENST00000393766.2
ENST00000504317.1
methylsterol monooxygenase 1
chr11_-_10315741 0.13 ENST00000256190.8
SET binding factor 2
chr3_-_124774802 0.13 ENST00000311127.4
heart development protein with EGF-like domains 1
chr5_+_125935960 0.13 ENST00000297540.4
phosphorylated adaptor for RNA export
chrX_+_131157290 0.13 ENST00000394334.2
Serine/threonine-protein kinase MST4
chr2_-_68694390 0.13 ENST00000377957.3
F-box protein 48
chr18_+_59854480 0.13 ENST00000256858.6
ENST00000398130.2
KIAA1468
chr6_+_64281906 0.13 ENST00000370651.3
protein tyrosine phosphatase type IVA, member 1
chr7_-_75368248 0.13 ENST00000434438.2
ENST00000336926.6
huntingtin interacting protein 1
chr12_-_93323013 0.13 ENST00000322349.8
early endosome antigen 1
chr12_-_57082060 0.13 ENST00000448157.2
ENST00000414274.3
ENST00000262033.6
ENST00000456859.2
prostaglandin E synthase 3 (cytosolic)
chr11_-_19263145 0.13 ENST00000532666.1
ENST00000527884.1
E2F transcription factor 8
chr7_+_30323923 0.13 ENST00000323037.4
zinc and ring finger 2
chr3_+_186501336 0.13 ENST00000323963.5
ENST00000440191.2
ENST00000356531.5
eukaryotic translation initiation factor 4A2
chr15_-_51914996 0.13 ENST00000251076.5
Dmx-like 2
chr10_+_96162242 0.13 ENST00000225235.4
TBC1 domain family, member 12
chr2_+_203879568 0.13 ENST00000449802.1
neurobeachin-like 1
chr5_+_112312416 0.12 ENST00000389063.2
decapping mRNA 2
chr4_-_71705590 0.12 ENST00000254799.6
G-rich RNA sequence binding factor 1
chr2_-_161350305 0.12 ENST00000348849.3
RNA binding motif, single stranded interacting protein 1
chr5_-_56247935 0.12 ENST00000381199.3
ENST00000381226.3
ENST00000381213.3
mesoderm induction early response 1, family member 3
chr2_-_153032484 0.12 ENST00000263904.4
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr9_-_80646374 0.12 ENST00000286548.4
guanine nucleotide binding protein (G protein), q polypeptide
chr4_+_153701081 0.12 ENST00000451320.2
ENST00000429148.2
ENST00000353617.2
ENST00000405727.2
ENST00000356064.3
ADP-ribosylation factor interacting protein 1
chr9_+_2015335 0.12 ENST00000349721.2
ENST00000357248.2
ENST00000450198.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_43732362 0.12 ENST00000458276.2
abhydrolase domain containing 5
chr5_-_73937244 0.12 ENST00000302351.4
ENST00000510316.1
ENST00000508331.1
ectodermal-neural cortex 1 (with BTB domain)
chr13_+_49550015 0.12 ENST00000492622.2
fibronectin type III domain containing 3A
chr5_-_171433819 0.12 ENST00000296933.6
F-box and WD repeat domain containing 11
chr16_+_22019404 0.11 ENST00000542527.2
ENST00000569656.1
ENST00000562695.1
chromosome 16 open reading frame 52
chr11_-_12030629 0.11 ENST00000396505.2
dickkopf WNT signaling pathway inhibitor 3
chr22_-_46373004 0.11 ENST00000339464.4
wingless-type MMTV integration site family, member 7B
chr9_-_130742792 0.11 ENST00000373095.1
family with sequence similarity 102, member A
chrX_+_117480036 0.11 ENST00000371822.5
ENST00000254029.3
ENST00000371825.3
WD repeat domain 44
chr20_-_524455 0.11 ENST00000349736.5
ENST00000217244.3
casein kinase 2, alpha 1 polypeptide
chr10_-_73611046 0.11 ENST00000394934.1
ENST00000394936.3
prosaposin
chr16_+_19125252 0.11 ENST00000566735.1
ENST00000381440.3
inositol 1,4,5-trisphosphate receptor interacting protein-like 2
chr11_-_95522907 0.11 ENST00000358780.5
ENST00000542135.1
family with sequence similarity 76, member B
chrX_+_17393543 0.11 ENST00000380060.3
Nance-Horan syndrome (congenital cataracts and dental anomalies)
chr5_+_98104978 0.11 ENST00000308234.7
repulsive guidance molecule family member b
chr5_-_40798263 0.11 ENST00000296800.4
ENST00000397128.2
protein kinase, AMP-activated, alpha 1 catalytic subunit
chr12_-_50419177 0.11 ENST00000454520.2
ENST00000546595.1
ENST00000548824.1
ENST00000549777.1
ENST00000546723.1
ENST00000427314.2
ENST00000552157.1
ENST00000552310.1
ENST00000548644.1
ENST00000312377.5
ENST00000546786.1
ENST00000550149.1
ENST00000546764.1
ENST00000552004.1
ENST00000548320.1
ENST00000547905.1
ENST00000550651.1
ENST00000551145.1
ENST00000434422.1
ENST00000552921.1
Rac GTPase activating protein 1
chr19_+_34745442 0.11 ENST00000299505.6
ENST00000588470.1
ENST00000589583.1
ENST00000588338.2
KIAA0355
chr1_-_214724566 0.11 ENST00000366956.5
protein tyrosine phosphatase, non-receptor type 14

Network of associatons between targets according to the STRING database.

First level regulatory network of GUGCAAA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.5 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283)
0.1 0.2 GO:0034059 response to anoxia(GO:0034059)
0.1 0.3 GO:1903984 negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.4 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.1 0.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.1 0.2 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.2 GO:1904761 negative regulation of myofibroblast differentiation(GO:1904761)
0.0 0.2 GO:0060535 trachea cartilage morphogenesis(GO:0060535)
0.0 0.3 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.2 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.2 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.1 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.0 0.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.1 GO:0061110 dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705)
0.0 0.1 GO:1904586 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.1 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.3 GO:0006065 UDP-glucuronate biosynthetic process(GO:0006065)
0.0 0.1 GO:0006408 snRNA export from nucleus(GO:0006408)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.3 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.3 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.3 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0098939 dendritic transport of mitochondrion(GO:0098939) anterograde dendritic transport of mitochondrion(GO:0098972)
0.0 0.1 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.4 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.3 GO:0007028 cytoplasm organization(GO:0007028)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.2 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.7 GO:0032486 Rap protein signal transduction(GO:0032486)
0.0 0.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.2 GO:0038180 nerve growth factor signaling pathway(GO:0038180) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.0 0.1 GO:0046041 ITP metabolic process(GO:0046041)
0.0 0.1 GO:1905246 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.3 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:0051459 regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0 0.1 GO:0090270 fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.0 0.3 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.2 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.3 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:1904647 response to rotenone(GO:1904647)
0.0 0.2 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.1 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.1 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0032345 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0010645 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.0 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.0 GO:0090325 regulation of locomotion involved in locomotory behavior(GO:0090325)
0.0 0.2 GO:0055089 fatty acid homeostasis(GO:0055089)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.0 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.1 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.0 GO:0060730 regulation of intestinal epithelial structure maintenance(GO:0060730)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.3 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.0 GO:0034402 recruitment of 3'-end processing factors to RNA polymerase II holoenzyme complex(GO:0034402)
0.0 0.1 GO:1990253 cellular response to leucine(GO:0071233) cellular response to leucine starvation(GO:1990253)
0.0 0.0 GO:0048627 myoblast development(GO:0048627)
0.0 0.1 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.0 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.0 GO:0060994 regulation of transcription from RNA polymerase II promoter involved in kidney development(GO:0060994)
0.0 0.0 GO:0016094 polyprenol biosynthetic process(GO:0016094)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.1 GO:0071409 cellular response to cycloheximide(GO:0071409)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0044308 axonal spine(GO:0044308)
0.1 0.2 GO:0070931 Golgi-associated vesicle lumen(GO:0070931)
0.1 0.2 GO:0070195 growth hormone receptor complex(GO:0070195)
0.1 0.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.3 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.2 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.0 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0051286 cell tip(GO:0051286)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.3 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.1 0.3 GO:0071633 dihydroceramidase activity(GO:0071633)
0.1 0.3 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142) phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.3 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.4 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.1 GO:0047676 arachidonate-CoA ligase activity(GO:0047676)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.1 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.2 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.0 GO:0003714 transcription corepressor activity(GO:0003714)
0.0 0.4 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.1 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.0 0.2 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.2 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 1.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.0 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.2 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.0 GO:0016005 phospholipase A2 activator activity(GO:0016005)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.1 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.6 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.6 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation