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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for GRHL1
Z-value: 0.30
Motif logo
Transcription factors associated with GRHL1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
GRHL1
|
ENSG00000134317.13 | grainyhead like transcription factor 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| GRHL1 | hg19_v2_chr2_+_10091783_10091811 | 0.12 | 8.3e-01 | Click! |
Activity profile of GRHL1 motif
Sorted Z-values of GRHL1 motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_-_153113927 | 0.29 |
ENST00000368752.4
|
SPRR2B
|
small proline-rich protein 2B |
| chr14_-_62217779 | 0.14 |
ENST00000554254.1
|
HIF1A-AS2
|
HIF1A antisense RNA 2 |
| chr19_+_45312310 | 0.13 |
ENST00000589651.1
|
BCAM
|
basal cell adhesion molecule (Lutheran blood group) |
| chr20_-_18038521 | 0.11 |
ENST00000278780.6
|
OVOL2
|
ovo-like zinc finger 2 |
| chr3_+_101568349 | 0.10 |
ENST00000326151.5
ENST00000326172.5 |
NFKBIZ
|
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta |
| chr1_-_234667504 | 0.10 |
ENST00000421207.1
ENST00000435574.1 |
RP5-855F14.1
|
RP5-855F14.1 |
| chr5_+_134303591 | 0.09 |
ENST00000282611.6
|
CATSPER3
|
cation channel, sperm associated 3 |
| chr19_+_45312347 | 0.09 |
ENST00000270233.6
ENST00000591520.1 |
BCAM
|
basal cell adhesion molecule (Lutheran blood group) |
| chr1_+_206643806 | 0.08 |
ENST00000537984.1
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| chr4_+_26859300 | 0.08 |
ENST00000494628.2
|
STIM2
|
stromal interaction molecule 2 |
| chr7_+_76139925 | 0.08 |
ENST00000394849.1
|
UPK3B
|
uroplakin 3B |
| chr11_-_93583697 | 0.07 |
ENST00000409977.1
|
VSTM5
|
V-set and transmembrane domain containing 5 |
| chr22_+_18560743 | 0.07 |
ENST00000399744.3
|
PEX26
|
peroxisomal biogenesis factor 26 |
| chr19_-_12405689 | 0.07 |
ENST00000355684.5
|
ZNF44
|
zinc finger protein 44 |
| chr6_-_31107127 | 0.07 |
ENST00000259845.4
|
PSORS1C2
|
psoriasis susceptibility 1 candidate 2 |
| chr6_-_43027105 | 0.06 |
ENST00000230413.5
ENST00000487429.1 ENST00000489623.1 ENST00000468957.1 |
MRPL2
|
mitochondrial ribosomal protein L2 |
| chr7_+_76139833 | 0.06 |
ENST00000257632.5
|
UPK3B
|
uroplakin 3B |
| chr21_+_33671264 | 0.06 |
ENST00000339944.4
|
MRAP
|
melanocortin 2 receptor accessory protein |
| chr3_-_58643458 | 0.06 |
ENST00000498347.1
|
FAM3D
|
family with sequence similarity 3, member D |
| chr19_-_4043154 | 0.05 |
ENST00000535853.1
|
AC016586.1
|
AC016586.1 |
| chr11_-_67442196 | 0.05 |
ENST00000525827.1
|
ALDH3B2
|
aldehyde dehydrogenase 3 family, member B2 |
| chr19_-_12405606 | 0.04 |
ENST00000356109.5
|
ZNF44
|
zinc finger protein 44 |
| chr14_-_23540747 | 0.04 |
ENST00000555566.1
ENST00000338631.6 ENST00000557515.1 ENST00000397341.3 |
ACIN1
|
apoptotic chromatin condensation inducer 1 |
| chr9_+_140122018 | 0.04 |
ENST00000445101.2
|
RNF224
|
ring finger protein 224 |
| chr2_+_95940220 | 0.04 |
ENST00000542147.1
|
PROM2
|
prominin 2 |
| chr1_+_44440575 | 0.04 |
ENST00000532642.1
ENST00000236067.4 ENST00000471859.2 |
ATP6V0B
|
ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b |
| chr18_-_35145981 | 0.04 |
ENST00000420428.2
ENST00000412753.1 |
CELF4
|
CUGBP, Elav-like family member 4 |
| chr14_-_23540826 | 0.04 |
ENST00000357481.2
|
ACIN1
|
apoptotic chromatin condensation inducer 1 |
| chr1_+_206643787 | 0.04 |
ENST00000367120.3
|
IKBKE
|
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon |
| chr5_+_125759140 | 0.03 |
ENST00000543198.1
|
GRAMD3
|
GRAM domain containing 3 |
| chr19_-_35981358 | 0.03 |
ENST00000484218.2
ENST00000338897.3 |
KRTDAP
|
keratinocyte differentiation-associated protein |
| chr4_-_129209944 | 0.03 |
ENST00000520121.1
|
PGRMC2
|
progesterone receptor membrane component 2 |
| chr19_+_19496728 | 0.03 |
ENST00000537887.1
ENST00000417582.2 |
GATAD2A
|
GATA zinc finger domain containing 2A |
| chr16_+_2564254 | 0.03 |
ENST00000565223.1
|
ATP6V0C
|
ATPase, H+ transporting, lysosomal 16kDa, V0 subunit c |
| chr1_-_24469602 | 0.03 |
ENST00000270800.1
|
IL22RA1
|
interleukin 22 receptor, alpha 1 |
| chr14_-_80677815 | 0.03 |
ENST00000557125.1
ENST00000555750.1 |
DIO2
|
deiodinase, iodothyronine, type II |
| chr4_+_110736659 | 0.03 |
ENST00000394631.3
ENST00000226796.6 |
GAR1
|
GAR1 ribonucleoprotein |
| chr19_+_10736183 | 0.03 |
ENST00000590857.1
ENST00000588688.1 ENST00000586078.1 |
SLC44A2
|
solute carrier family 44 (choline transporter), member 2 |
| chr19_+_1491144 | 0.03 |
ENST00000233596.3
|
REEP6
|
receptor accessory protein 6 |
| chr2_+_113816215 | 0.03 |
ENST00000346807.3
|
IL36RN
|
interleukin 36 receptor antagonist |
| chr17_-_60883993 | 0.02 |
ENST00000583803.1
ENST00000456609.2 |
MARCH10
|
membrane-associated ring finger (C3HC4) 10, E3 ubiquitin protein ligase |
| chr11_+_119039414 | 0.02 |
ENST00000409991.1
ENST00000292199.2 ENST00000409265.4 ENST00000409109.1 |
NLRX1
|
NLR family member X1 |
| chr11_-_111636772 | 0.02 |
ENST00000531373.1
|
PPP2R1B
|
protein phosphatase 2, regulatory subunit A, beta |
| chr1_+_155023757 | 0.02 |
ENST00000356955.2
ENST00000449910.2 ENST00000359280.4 ENST00000360674.4 ENST00000368412.3 ENST00000355956.2 ENST00000368410.2 ENST00000271836.6 ENST00000368413.1 ENST00000531455.1 ENST00000447332.3 |
ADAM15
|
ADAM metallopeptidase domain 15 |
| chr11_+_706595 | 0.02 |
ENST00000531348.1
ENST00000530636.1 |
EPS8L2
|
EPS8-like 2 |
| chr4_-_69083720 | 0.02 |
ENST00000432593.3
|
TMPRSS11BNL
|
TMPRSS11B N-terminal like |
| chr13_+_48807288 | 0.02 |
ENST00000378565.5
|
ITM2B
|
integral membrane protein 2B |
| chr8_+_144821557 | 0.02 |
ENST00000534398.1
|
FAM83H-AS1
|
FAM83H antisense RNA 1 (head to head) |
| chr4_-_68995571 | 0.02 |
ENST00000356291.2
|
TMPRSS11F
|
transmembrane protease, serine 11F |
| chr7_+_76139741 | 0.02 |
ENST00000334348.3
ENST00000419923.2 ENST00000448265.3 ENST00000443097.2 |
UPK3B
|
uroplakin 3B |
| chr9_+_130565487 | 0.02 |
ENST00000373225.3
ENST00000431857.1 |
FPGS
|
folylpolyglutamate synthase |
| chr10_+_81838411 | 0.02 |
ENST00000372281.3
ENST00000372277.3 ENST00000372275.1 ENST00000372274.1 |
TMEM254
|
transmembrane protein 254 |
| chr2_-_85641162 | 0.02 |
ENST00000447219.2
ENST00000409670.1 ENST00000409724.1 |
CAPG
|
capping protein (actin filament), gelsolin-like |
| chr14_-_80677613 | 0.02 |
ENST00000556811.1
|
DIO2
|
deiodinase, iodothyronine, type II |
| chr9_+_71736177 | 0.01 |
ENST00000606364.1
ENST00000453658.2 |
TJP2
|
tight junction protein 2 |
| chr19_+_19496624 | 0.01 |
ENST00000494516.2
ENST00000360315.3 ENST00000252577.5 |
GATAD2A
|
GATA zinc finger domain containing 2A |
| chr9_+_104161123 | 0.01 |
ENST00000374861.3
ENST00000339664.2 ENST00000259395.4 |
ZNF189
|
zinc finger protein 189 |
| chr2_+_95940186 | 0.01 |
ENST00000403131.2
ENST00000317668.4 ENST00000317620.9 |
PROM2
|
prominin 2 |
| chr1_-_52520828 | 0.01 |
ENST00000610127.1
|
TXNDC12
|
thioredoxin domain containing 12 (endoplasmic reticulum) |
| chr19_-_291133 | 0.01 |
ENST00000327790.3
|
PPAP2C
|
phosphatidic acid phosphatase type 2C |
| chr12_+_56498312 | 0.01 |
ENST00000552766.1
|
PA2G4
|
proliferation-associated 2G4, 38kDa |
| chr11_+_119038897 | 0.01 |
ENST00000454811.1
ENST00000449394.1 |
NLRX1
|
NLR family member X1 |
| chr7_-_29152509 | 0.01 |
ENST00000448959.1
|
CPVL
|
carboxypeptidase, vitellogenic-like |
| chr1_+_244515930 | 0.01 |
ENST00000366537.1
ENST00000308105.4 |
C1orf100
|
chromosome 1 open reading frame 100 |
| chr5_-_132299290 | 0.01 |
ENST00000378595.3
|
AFF4
|
AF4/FMR2 family, member 4 |
| chr11_+_119039069 | 0.01 |
ENST00000422249.1
|
NLRX1
|
NLR family member X1 |
| chr14_+_23938891 | 0.01 |
ENST00000408901.3
ENST00000397154.3 ENST00000555128.1 |
NGDN
|
neuroguidin, EIF4E binding protein |
| chr1_-_16539094 | 0.01 |
ENST00000270747.3
|
ARHGEF19
|
Rho guanine nucleotide exchange factor (GEF) 19 |
| chr9_+_130565568 | 0.01 |
ENST00000423577.1
|
FPGS
|
folylpolyglutamate synthase |
| chr19_-_14945933 | 0.01 |
ENST00000322301.3
|
OR7A5
|
olfactory receptor, family 7, subfamily A, member 5 |
| chr16_-_23568651 | 0.01 |
ENST00000563232.1
ENST00000563459.1 ENST00000449606.1 |
EARS2
|
glutamyl-tRNA synthetase 2, mitochondrial |
| chr8_+_27950619 | 0.01 |
ENST00000542181.1
ENST00000524103.1 ENST00000537665.1 ENST00000380353.4 ENST00000520288.1 |
ELP3
|
elongator acetyltransferase complex subunit 3 |
| chr5_-_132299313 | 0.01 |
ENST00000265343.5
|
AFF4
|
AF4/FMR2 family, member 4 |
| chr19_-_17356697 | 0.01 |
ENST00000291442.3
|
NR2F6
|
nuclear receptor subfamily 2, group F, member 6 |
| chr1_+_35247859 | 0.01 |
ENST00000373362.3
|
GJB3
|
gap junction protein, beta 3, 31kDa |
| chr18_-_35145728 | 0.01 |
ENST00000361795.5
ENST00000603232.1 |
CELF4
|
CUGBP, Elav-like family member 4 |
| chr12_+_18414446 | 0.00 |
ENST00000433979.1
|
PIK3C2G
|
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma |
| chr4_+_156588249 | 0.00 |
ENST00000393832.3
|
GUCY1A3
|
guanylate cyclase 1, soluble, alpha 3 |
| chr1_-_36863481 | 0.00 |
ENST00000315732.2
|
LSM10
|
LSM10, U7 small nuclear RNA associated |
| chr22_+_18560675 | 0.00 |
ENST00000329627.7
|
PEX26
|
peroxisomal biogenesis factor 26 |
| chrX_+_146993449 | 0.00 |
ENST00000218200.8
ENST00000370471.3 ENST00000370477.1 |
FMR1
|
fragile X mental retardation 1 |
| chr19_-_12146483 | 0.00 |
ENST00000455504.2
ENST00000547560.1 ENST00000552904.1 ENST00000419886.2 ENST00000550507.1 ENST00000344980.6 ENST00000550745.1 ENST00000411841.1 |
ZNF433
|
zinc finger protein 433 |
| chr12_+_118814185 | 0.00 |
ENST00000543473.1
|
SUDS3
|
suppressor of defective silencing 3 homolog (S. cerevisiae) |
Network of associatons between targets according to the STRING database.
First level regulatory network of GRHL1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0060214 | endocardium formation(GO:0060214) |
| 0.0 | 0.1 | GO:2001287 | negative regulation of caveolin-mediated endocytosis(GO:2001287) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0044393 | microspike(GO:0044393) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.2 | GO:0005055 | laminin receptor activity(GO:0005055) |
| 0.0 | 0.1 | GO:0008384 | IkappaB kinase activity(GO:0008384) K48-linked polyubiquitin binding(GO:0036435) |
| 0.0 | 0.1 | GO:0031783 | corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783) |