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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GLI2

Z-value: 0.82

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Transcription factors associated with GLI2

Gene Symbol Gene ID Gene Info
GLI2
ENSG00000074047.16 GLI family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
GLI2hg19_v2_chr2_+_121493717_121493823-0.394.4e-01Click!

Activity profile of GLI2 motif

Sorted Z-values of GLI2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_45417504 0.53 ENST00000588750.1
ENST00000588802.1
APOC1
apolipoprotein C-I
chr19_+_45417921 0.46 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
APOC1
apolipoprotein C-I
chr12_-_13529594 0.44 ENST00000539026.1
C12orf36
chromosome 12 open reading frame 36
chr14_+_106938440 0.29 ENST00000433371.1
ENST00000449670.1
ENST00000334298.3
LINC00221
long intergenic non-protein coding RNA 221
chr17_+_29248953 0.27 ENST00000581285.1
ADAP2
ArfGAP with dual PH domains 2
chr2_-_197041044 0.26 ENST00000420683.1
STK17B
serine/threonine kinase 17b
chr8_+_96145974 0.26 ENST00000315367.3
PLEKHF2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr11_-_111383064 0.26 ENST00000525791.1
ENST00000456861.2
ENST00000356018.2
BTG4
B-cell translocation gene 4
chr19_-_40562063 0.24 ENST00000598845.1
ENST00000593605.1
ENST00000221355.6
ENST00000434248.1
ZNF780B
zinc finger protein 780B
chr16_-_30064244 0.24 ENST00000571269.1
ENST00000561666.1
FAM57B
family with sequence similarity 57, member B
chr14_+_21467414 0.24 ENST00000554422.1
ENST00000298681.4
SLC39A2
solute carrier family 39 (zinc transporter), member 2
chr11_-_299519 0.24 ENST00000382614.2
IFITM5
interferon induced transmembrane protein 5
chr18_-_59274139 0.23 ENST00000586949.1
RP11-879F14.2
RP11-879F14.2
chr6_-_121655850 0.23 ENST00000422369.1
TBC1D32
TBC1 domain family, member 32
chr12_+_132568814 0.22 ENST00000454179.2
ENST00000389560.2
ENST00000443539.2
ENST00000392352.1
EP400NL
EP400 N-terminal like
chr9_+_132427883 0.22 ENST00000372469.4
PRRX2
paired related homeobox 2
chr8_+_74888417 0.21 ENST00000517439.1
ENST00000312184.5
TMEM70
transmembrane protein 70
chr1_-_32403370 0.21 ENST00000534796.1
PTP4A2
protein tyrosine phosphatase type IVA, member 2
chr11_+_68451943 0.21 ENST00000265643.3
GAL
galanin/GMAP prepropeptide
chrX_-_135056106 0.21 ENST00000433339.2
MMGT1
membrane magnesium transporter 1
chr7_+_142985467 0.21 ENST00000392925.2
CASP2
caspase 2, apoptosis-related cysteine peptidase
chr14_+_105147464 0.21 ENST00000540171.2
RP11-982M15.6
RP11-982M15.6
chr21_-_44035168 0.20 ENST00000419628.1
AP001626.1
AP001626.1
chr12_-_110883346 0.19 ENST00000547365.1
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr11_-_73720276 0.19 ENST00000348534.4
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr17_+_29248918 0.19 ENST00000581548.1
ENST00000580525.1
ADAP2
ArfGAP with dual PH domains 2
chr8_+_144371773 0.18 ENST00000523891.1
ZNF696
zinc finger protein 696
chr6_+_26204825 0.18 ENST00000360441.4
HIST1H4E
histone cluster 1, H4e
chr19_-_44084586 0.18 ENST00000599693.1
ENST00000598165.1
XRCC1
X-ray repair complementing defective repair in Chinese hamster cells 1
chr2_-_214017151 0.18 ENST00000452786.1
IKZF2
IKAROS family zinc finger 2 (Helios)
chr19_-_48673465 0.18 ENST00000598938.1
LIG1
ligase I, DNA, ATP-dependent
chrX_+_153146127 0.18 ENST00000452593.1
ENST00000357566.1
LCA10
Putative lung carcinoma-associated protein 10
chr7_-_127032363 0.18 ENST00000393312.1
ZNF800
zinc finger protein 800
chr17_-_76274572 0.18 ENST00000374945.1
RP11-219G17.4
RP11-219G17.4
chr1_+_153600869 0.18 ENST00000292169.1
ENST00000368696.3
ENST00000436839.1
S100A1
S100 calcium binding protein A1
chr1_+_228362251 0.18 ENST00000546123.1
IBA57
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr22_+_23248512 0.17 ENST00000390325.2
IGLC3
immunoglobulin lambda constant 3 (Kern-Oz+ marker)
chr16_+_2880254 0.17 ENST00000570670.1
ZG16B
zymogen granule protein 16B
chr16_-_71842706 0.17 ENST00000563104.1
ENST00000569975.1
ENST00000565412.1
ENST00000567583.1
AP1G1
adaptor-related protein complex 1, gamma 1 subunit
chr11_-_111649015 0.17 ENST00000529841.1
RP11-108O10.2
RP11-108O10.2
chr1_+_152486950 0.17 ENST00000368790.3
CRCT1
cysteine-rich C-terminal 1
chr22_-_46450024 0.17 ENST00000396008.2
ENST00000333761.1
C22orf26
chromosome 22 open reading frame 26
chr6_-_53530474 0.17 ENST00000370905.3
KLHL31
kelch-like family member 31
chr6_-_121655593 0.17 ENST00000398212.2
TBC1D32
TBC1 domain family, member 32
chr10_-_120938303 0.17 ENST00000356951.3
ENST00000298510.2
PRDX3
peroxiredoxin 3
chr2_+_131369054 0.16 ENST00000409602.1
POTEJ
POTE ankyrin domain family, member J
chr7_-_960521 0.16 ENST00000437486.1
ADAP1
ArfGAP with dual PH domains 1
chr19_+_17858547 0.16 ENST00000600676.1
ENST00000600209.1
ENST00000596309.1
ENST00000598539.1
ENST00000597474.1
ENST00000593385.1
ENST00000598067.1
ENST00000593833.1
FCHO1
FCH domain only 1
chr1_-_41487383 0.16 ENST00000302946.8
ENST00000372613.2
ENST00000439569.2
ENST00000397197.2
SLFNL1
schlafen-like 1
chr17_+_1733251 0.16 ENST00000570451.1
RPA1
replication protein A1, 70kDa
chr1_-_21978312 0.16 ENST00000359708.4
ENST00000290101.4
RAP1GAP
RAP1 GTPase activating protein
chr1_+_6845578 0.16 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr3_+_11313995 0.16 ENST00000451513.1
ENST00000435760.1
ENST00000451830.1
ATG7
autophagy related 7
chr11_-_73720122 0.15 ENST00000426995.2
UCP3
uncoupling protein 3 (mitochondrial, proton carrier)
chr9_-_35042824 0.15 ENST00000595331.1
FLJ00273
FLJ00273
chr22_+_20008646 0.15 ENST00000401833.1
TANGO2
transport and golgi organization 2 homolog (Drosophila)
chr6_-_121655552 0.15 ENST00000275159.6
TBC1D32
TBC1 domain family, member 32
chr16_-_15736345 0.15 ENST00000549219.1
KIAA0430
KIAA0430
chr10_+_14880364 0.15 ENST00000441647.1
HSPA14
heat shock 70kDa protein 14
chr7_-_92465868 0.15 ENST00000424848.2
CDK6
cyclin-dependent kinase 6
chr1_-_2343951 0.15 ENST00000288774.3
ENST00000507596.1
ENST00000447513.2
PEX10
peroxisomal biogenesis factor 10
chr19_+_45417812 0.15 ENST00000592535.1
APOC1
apolipoprotein C-I
chr10_-_105156198 0.15 ENST00000369815.1
ENST00000309579.3
ENST00000337003.4
USMG5
up-regulated during skeletal muscle growth 5 homolog (mouse)
chr3_+_129207033 0.14 ENST00000507221.1
IFT122
intraflagellar transport 122 homolog (Chlamydomonas)
chr19_-_49176264 0.14 ENST00000270235.4
ENST00000596844.1
NTN5
netrin 5
chr1_-_16563641 0.14 ENST00000375599.3
RSG1
REM2 and RAB-like small GTPase 1
chr6_+_89790459 0.14 ENST00000369472.1
PNRC1
proline-rich nuclear receptor coactivator 1
chr17_+_46185111 0.14 ENST00000582104.1
ENST00000584335.1
SNX11
sorting nexin 11
chr11_-_34938039 0.14 ENST00000395787.3
APIP
APAF1 interacting protein
chr19_+_58962971 0.14 ENST00000336614.4
ENST00000545523.1
ENST00000599194.1
ENST00000598244.1
ENST00000599193.1
ENST00000594214.1
ENST00000391696.1
ZNF324B
zinc finger protein 324B
chr1_+_6845497 0.14 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr3_-_25824353 0.14 ENST00000427041.1
NGLY1
N-glycanase 1
chr3_-_45957088 0.14 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr21_-_28215332 0.14 ENST00000517777.1
ADAMTS1
ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr4_+_57843876 0.14 ENST00000450656.1
ENST00000381227.1
POLR2B
polymerase (RNA) II (DNA directed) polypeptide B, 140kDa
chr1_-_86861936 0.14 ENST00000394733.2
ENST00000359242.3
ENST00000294678.2
ENST00000479890.1
ENST00000317336.7
ENST00000370567.1
ENST00000394731.1
ENST00000478286.2
ENST00000370566.3
ODF2L
outer dense fiber of sperm tails 2-like
chr22_+_20008595 0.14 ENST00000398042.2
ENST00000450664.1
ENST00000327374.4
ENST00000432883.1
TANGO2
transport and golgi organization 2 homolog (Drosophila)
chr11_-_31531121 0.14 ENST00000532287.1
ENST00000526776.1
ENST00000534812.1
ENST00000529749.1
ENST00000278200.1
ENST00000530023.1
ENST00000533642.1
IMMP1L
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr21_-_40555393 0.14 ENST00000380900.2
PSMG1
proteasome (prosome, macropain) assembly chaperone 1
chr8_+_96146168 0.14 ENST00000519516.1
PLEKHF2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr6_-_30685214 0.14 ENST00000425072.1
MDC1
mediator of DNA-damage checkpoint 1
chr14_-_52535712 0.14 ENST00000216286.5
ENST00000541773.1
NID2
nidogen 2 (osteonidogen)
chr16_-_85146040 0.14 ENST00000539556.1
FAM92B
family with sequence similarity 92, member B
chr1_-_85358850 0.14 ENST00000370611.3
LPAR3
lysophosphatidic acid receptor 3
chr5_-_177659539 0.13 ENST00000476170.2
PHYKPL
5-phosphohydroxy-L-lysine phospho-lyase
chr8_-_86132568 0.13 ENST00000321777.5
ENST00000458398.2
ENST00000431163.2
ENST00000417663.2
ENST00000524353.1
ENST00000421308.2
ENST00000545322.1
ENST00000518562.1
C8orf59
chromosome 8 open reading frame 59
chrX_+_70503526 0.13 ENST00000413858.1
ENST00000450092.1
NONO
non-POU domain containing, octamer-binding
chr2_+_183989157 0.13 ENST00000541912.1
NUP35
nucleoporin 35kDa
chr11_-_118550346 0.13 ENST00000530256.1
TREH
trehalase (brush-border membrane glycoprotein)
chr1_+_14026671 0.13 ENST00000484063.2
PRDM2
PR domain containing 2, with ZNF domain
chr22_+_23243156 0.13 ENST00000390323.2
IGLC2
immunoglobulin lambda constant 2 (Kern-Oz- marker)
chr22_-_50970506 0.13 ENST00000428989.2
ENST00000403326.1
ODF3B
outer dense fiber of sperm tails 3B
chr17_-_30185946 0.13 ENST00000579741.1
COPRS
coordinator of PRMT5, differentiation stimulator
chr10_+_6821545 0.13 ENST00000436383.1
LINC00707
long intergenic non-protein coding RNA 707
chr11_-_63439013 0.13 ENST00000398868.3
ATL3
atlastin GTPase 3
chr3_-_155524049 0.13 ENST00000534941.1
ENST00000340171.2
C3orf33
chromosome 3 open reading frame 33
chrX_+_17755563 0.13 ENST00000380045.3
ENST00000380041.3
ENST00000380043.3
ENST00000398080.1
SCML1
sex comb on midleg-like 1 (Drosophila)
chr6_-_99963286 0.13 ENST00000369233.2
ENST00000500704.2
ENST00000329966.6
USP45
ubiquitin specific peptidase 45
chr5_-_89705537 0.13 ENST00000522864.1
ENST00000522083.1
ENST00000522565.1
ENST00000522842.1
ENST00000283122.3
CETN3
centrin, EF-hand protein, 3
chr17_-_80059726 0.12 ENST00000583053.1
CCDC57
coiled-coil domain containing 57
chr8_+_7705398 0.12 ENST00000400125.2
ENST00000434307.2
ENST00000326558.5
ENST00000351436.4
ENST00000528033.1
SPAG11A
sperm associated antigen 11A
chr8_-_7320974 0.12 ENST00000528943.1
ENST00000359758.5
ENST00000361111.2
ENST00000398462.2
ENST00000297498.2
ENST00000317900.5
SPAG11B
sperm associated antigen 11B
chr2_-_224702201 0.12 ENST00000446015.2
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr22_-_29137771 0.12 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2
checkpoint kinase 2
chr11_-_111649074 0.12 ENST00000534218.1
RP11-108O10.2
RP11-108O10.2
chr3_-_72496035 0.12 ENST00000477973.2
RYBP
RING1 and YY1 binding protein
chr11_+_123301012 0.12 ENST00000533341.1
AP000783.1
Uncharacterized protein
chr17_+_80517216 0.12 ENST00000531030.1
ENST00000526383.2
FOXK2
forkhead box K2
chr9_+_108456800 0.12 ENST00000434214.1
ENST00000374692.3
TMEM38B
transmembrane protein 38B
chr10_-_23633720 0.12 ENST00000323327.4
C10orf67
chromosome 10 open reading frame 67
chr12_-_48099754 0.12 ENST00000380650.4
RPAP3
RNA polymerase II associated protein 3
chr11_-_34937858 0.12 ENST00000278359.5
APIP
APAF1 interacting protein
chr5_-_95297534 0.12 ENST00000513343.1
ENST00000431061.2
ELL2
elongation factor, RNA polymerase II, 2
chr17_-_60005365 0.12 ENST00000444766.3
INTS2
integrator complex subunit 2
chr19_-_49522727 0.12 ENST00000600007.1
CTB-60B18.10
CTB-60B18.10
chr5_-_176923846 0.12 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr9_+_15553000 0.12 ENST00000297641.3
CCDC171
coiled-coil domain containing 171
chr3_-_195538728 0.11 ENST00000349607.4
ENST00000346145.4
MUC4
mucin 4, cell surface associated
chr4_+_95128996 0.11 ENST00000457823.2
SMARCAD1
SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr22_-_29138386 0.11 ENST00000544772.1
CHEK2
checkpoint kinase 2
chr3_+_112930387 0.11 ENST00000485230.1
BOC
BOC cell adhesion associated, oncogene regulated
chrX_-_30326445 0.11 ENST00000378963.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr11_-_71751715 0.11 ENST00000535947.1
NUMA1
nuclear mitotic apparatus protein 1
chr19_+_56989485 0.11 ENST00000585445.1
ENST00000586091.1
ENST00000594783.1
ENST00000592146.1
ENST00000588158.1
ENST00000299997.4
ENST00000591797.1
ZNF667-AS1
ZNF667 antisense RNA 1 (head to head)
chr9_-_35071960 0.11 ENST00000417448.1
VCP
valosin containing protein
chr1_-_59012365 0.11 ENST00000456980.1
ENST00000482274.2
ENST00000453710.1
ENST00000419242.1
ENST00000358603.2
ENST00000371226.3
ENST00000426139.1
OMA1
OMA1 zinc metallopeptidase
chr19_-_23941639 0.11 ENST00000395385.3
ENST00000531570.1
ENST00000528059.1
ZNF681
zinc finger protein 681
chr20_+_43514320 0.11 ENST00000372839.3
ENST00000428262.1
ENST00000445830.1
YWHAB
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
chr10_-_127408011 0.11 ENST00000531977.1
ENST00000527483.1
ENST00000525909.1
ENST00000528844.1
ENST00000423178.2
RP11-383C5.4
RP11-383C5.4
chr1_+_93646238 0.11 ENST00000448243.1
ENST00000370276.1
CCDC18
coiled-coil domain containing 18
chr3_-_194207388 0.11 ENST00000457986.1
ATP13A3
ATPase type 13A3
chr14_-_24615523 0.11 ENST00000559056.1
PSME2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr16_+_67063036 0.11 ENST00000290858.6
ENST00000564034.1
CBFB
core-binding factor, beta subunit
chr19_-_23941680 0.11 ENST00000402377.3
ZNF681
zinc finger protein 681
chr6_+_26273144 0.11 ENST00000377733.2
HIST1H2BI
histone cluster 1, H2bi
chr15_-_75917955 0.11 ENST00000568162.1
ENST00000563875.1
SNUPN
snurportin 1
chr14_-_75530693 0.11 ENST00000555135.1
ENST00000357971.3
ENST00000553302.1
ENST00000555694.1
ENST00000238618.3
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr17_-_30186328 0.11 ENST00000302362.6
COPRS
coordinator of PRMT5, differentiation stimulator
chrX_+_24073048 0.11 ENST00000423068.1
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr19_-_15343191 0.11 ENST00000221730.3
EPHX3
epoxide hydrolase 3
chr15_-_78526942 0.11 ENST00000258873.4
ACSBG1
acyl-CoA synthetase bubblegum family member 1
chr2_+_183989083 0.11 ENST00000295119.4
NUP35
nucleoporin 35kDa
chr7_+_30185496 0.11 ENST00000455738.1
C7orf41
maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr11_+_3875757 0.11 ENST00000525403.1
STIM1
stromal interaction molecule 1
chr19_-_10628098 0.11 ENST00000590601.1
S1PR5
sphingosine-1-phosphate receptor 5
chr5_-_82373260 0.11 ENST00000502346.1
TMEM167A
transmembrane protein 167A
chr11_-_118550375 0.11 ENST00000525958.1
ENST00000264029.4
ENST00000397925.1
ENST00000529101.1
TREH
trehalase (brush-border membrane glycoprotein)
chr11_+_31531291 0.11 ENST00000350638.5
ENST00000379163.5
ENST00000395934.2
ELP4
elongator acetyltransferase complex subunit 4
chr22_+_37447771 0.11 ENST00000402077.3
ENST00000403888.3
ENST00000456470.1
KCTD17
potassium channel tetramerization domain containing 17
chr17_+_18647326 0.11 ENST00000395667.1
ENST00000395665.4
ENST00000308799.4
ENST00000301938.4
FBXW10
F-box and WD repeat domain containing 10
chr22_+_39760130 0.11 ENST00000381535.4
SYNGR1
synaptogyrin 1
chr5_-_156569754 0.10 ENST00000420343.1
MED7
mediator complex subunit 7
chr19_+_37464063 0.10 ENST00000586353.1
ENST00000433993.1
ENST00000592567.1
ZNF568
zinc finger protein 568
chr2_+_11295624 0.10 ENST00000402361.1
ENST00000428481.1
PQLC3
PQ loop repeat containing 3
chr4_-_71705590 0.10 ENST00000254799.6
GRSF1
G-rich RNA sequence binding factor 1
chr19_-_16284286 0.10 ENST00000379859.3
ENST00000269878.4
CIB3
calcium and integrin binding family member 3
chr5_+_102455853 0.10 ENST00000515845.1
ENST00000321521.9
ENST00000507921.1
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr14_-_36983034 0.10 ENST00000518529.2
SFTA3
surfactant associated 3
chr19_-_37263723 0.10 ENST00000589390.1
ZNF850
zinc finger protein 850
chr9_-_139658965 0.10 ENST00000316144.5
LCN15
lipocalin 15
chr5_+_172332220 0.10 ENST00000518247.1
ENST00000326654.2
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr22_+_39410287 0.10 ENST00000381568.4
APOBEC3D
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
chrX_+_135618258 0.10 ENST00000440515.1
ENST00000456412.1
VGLL1
vestigial like 1 (Drosophila)
chr4_+_56814968 0.10 ENST00000422247.2
CEP135
centrosomal protein 135kDa
chr1_-_156269428 0.10 ENST00000339922.3
VHLL
von Hippel-Lindau tumor suppressor-like
chr1_+_225117350 0.10 ENST00000413949.2
ENST00000430092.1
ENST00000366850.3
ENST00000400952.3
ENST00000366849.1
DNAH14
dynein, axonemal, heavy chain 14
chr12_-_108991812 0.10 ENST00000392806.3
ENST00000547567.1
TMEM119
transmembrane protein 119
chr20_+_32782375 0.10 ENST00000568305.1
ASIP
agouti signaling protein
chr9_+_130860583 0.10 ENST00000373064.5
SLC25A25
solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 25
chr19_-_54567035 0.10 ENST00000366170.2
ENST00000425006.2
VSTM1
V-set and transmembrane domain containing 1
chr1_+_162531294 0.10 ENST00000367926.4
ENST00000271469.3
UAP1
UDP-N-acteylglucosamine pyrophosphorylase 1
chr1_+_154947126 0.10 ENST00000368439.1
CKS1B
CDC28 protein kinase regulatory subunit 1B
chr4_-_156298087 0.10 ENST00000311277.4
MAP9
microtubule-associated protein 9
chr5_-_89825328 0.10 ENST00000500869.2
ENST00000315948.6
ENST00000509384.1
LYSMD3
LysM, putative peptidoglycan-binding, domain containing 3
chr13_-_52026730 0.10 ENST00000420668.2
INTS6
integrator complex subunit 6
chr16_-_3285144 0.10 ENST00000431561.3
ENST00000396870.4
ZNF200
zinc finger protein 200
chr21_-_35340759 0.10 ENST00000607953.1
AP000569.9
AP000569.9
chr1_-_243417762 0.10 ENST00000522191.1
CEP170
centrosomal protein 170kDa
chr1_-_26232951 0.10 ENST00000426559.2
ENST00000455785.2
STMN1
stathmin 1
chr1_+_150522222 0.10 ENST00000369039.5
ADAMTSL4
ADAMTS-like 4
chr9_+_78505581 0.10 ENST00000376767.3
ENST00000376752.4
PCSK5
proprotein convertase subtilisin/kexin type 5
chr4_-_156297919 0.10 ENST00000450097.1
MAP9
microtubule-associated protein 9
chr4_-_156297949 0.09 ENST00000515654.1
MAP9
microtubule-associated protein 9
chr12_-_13529642 0.09 ENST00000318426.2
C12orf36
chromosome 12 open reading frame 36
chr4_-_107237374 0.09 ENST00000361687.4
ENST00000507696.1
ENST00000394708.2
ENST00000509532.1
TBCK
TBC1 domain containing kinase
chr6_-_99963252 0.09 ENST00000392738.2
ENST00000327681.6
ENST00000472914.2
USP45
ubiquitin specific peptidase 45
chr3_-_25824925 0.09 ENST00000396649.3
ENST00000428257.1
ENST00000280700.5
NGLY1
N-glycanase 1
chr10_-_14880002 0.09 ENST00000465530.1
CDNF
cerebral dopamine neurotrophic factor
chr2_+_219283815 0.09 ENST00000248444.5
ENST00000454069.1
ENST00000392114.2
VIL1
villin 1
chr22_+_29168652 0.09 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117
coiled-coil domain containing 117
chr20_+_44746939 0.09 ENST00000372276.3
CD40
CD40 molecule, TNF receptor superfamily member 5
chr18_+_12948000 0.09 ENST00000585730.1
ENST00000399892.2
ENST00000589446.1
ENST00000587761.1
SEH1L
SEH1-like (S. cerevisiae)
chr12_+_120740119 0.09 ENST00000536460.1
ENST00000202967.4
SIRT4
sirtuin 4
chr12_-_48099773 0.09 ENST00000432584.3
ENST00000005386.3
RPAP3
RNA polymerase II associated protein 3
chr8_-_128960591 0.09 ENST00000539634.1
TMEM75
transmembrane protein 75
chr3_+_156008809 0.09 ENST00000302490.8
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr17_-_71258019 0.09 ENST00000344935.4
CPSF4L
cleavage and polyadenylation specific factor 4-like
chr3_-_23958506 0.09 ENST00000425478.2
NKIRAS1
NFKB inhibitor interacting Ras-like 1
chr7_-_112726393 0.09 ENST00000449591.1
ENST00000449735.1
ENST00000438062.1
ENST00000424100.1
GPR85
G protein-coupled receptor 85
chr11_+_34938119 0.09 ENST00000227868.4
ENST00000430469.2
ENST00000533262.1
PDHX
pyruvate dehydrogenase complex, component X

Network of associatons between targets according to the STRING database.

First level regulatory network of GLI2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.1 0.2 GO:0072428 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.2 GO:0051795 positive regulation of catagen(GO:0051795)
0.1 0.2 GO:1903461 Okazaki fragment processing involved in mitotic DNA replication(GO:1903461)
0.1 0.2 GO:1904875 regulation of DNA ligase activity(GO:1904875)
0.1 0.2 GO:0034727 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521)
0.1 0.5 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.3 GO:0043323 regulation of natural killer cell degranulation(GO:0043321) positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.1 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.0 0.2 GO:0061015 snRNA import into nucleus(GO:0061015)
0.0 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.2 GO:0060434 bronchus morphogenesis(GO:0060434)
0.0 0.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0072387 flavin adenine dinucleotide metabolic process(GO:0072387)
0.0 0.1 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.0 0.1 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.0 0.1 GO:1903216 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.1 GO:0044209 AMP salvage(GO:0044209)
0.0 0.3 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.4 GO:1902412 regulation of mitotic cytokinesis(GO:1902412)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0051083 'de novo' cotranslational protein folding(GO:0051083)
0.0 0.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.1 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.1 GO:0060971 intraciliary anterograde transport(GO:0035720) ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.1 GO:0051389 inactivation of MAPKK activity(GO:0051389) trans-synaptic signaling by trans-synaptic complex(GO:0099545)
0.0 0.1 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.3 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.4 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.0 GO:0048864 stem cell development(GO:0048864)
0.0 0.1 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0071486 cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.4 GO:0034969 histone arginine methylation(GO:0034969)
0.0 0.1 GO:0000967 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 0.1 GO:0043366 beta selection(GO:0043366)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.0 0.1 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0045006 DNA deamination(GO:0045006)
0.0 0.0 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.0 0.0 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:2000969 positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.0 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.0 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.0 0.2 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.0 0.0 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.2 GO:1901387 positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0 0.1 GO:0043697 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.0 GO:0050904 diapedesis(GO:0050904)
0.0 0.1 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.1 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.0 0.1 GO:0061052 negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0 0.1 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:0036017 response to erythropoietin(GO:0036017) cellular response to erythropoietin(GO:0036018)
0.0 0.0 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.1 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.0 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.1 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.0 0.0 GO:2000282 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) regulation of cellular amino acid biosynthetic process(GO:2000282) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.1 GO:1901911 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0001999 renal response to blood flow involved in circulatory renin-angiotensin regulation of systemic arterial blood pressure(GO:0001999) renin secretion into blood stream(GO:0002001)
0.0 0.1 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.1 GO:0051295 establishment of meiotic spindle localization(GO:0051295) protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.0 0.1 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.0 GO:0003335 corneocyte development(GO:0003335)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0042627 chylomicron(GO:0042627)
0.1 0.2 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.2 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.5 GO:0005818 astral microtubule(GO:0000235) aster(GO:0005818)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.2 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.2 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.1 GO:0032301 MutSalpha complex(GO:0032301)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.2 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.0 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.1 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.1 0.3 GO:0000224 peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activity(GO:0000224)
0.1 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 0.6 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1 0.2 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.1 0.2 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.1 0.2 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.0 0.1 GO:0045142 triplex DNA binding(GO:0045142)
0.0 0.5 GO:0003909 DNA ligase activity(GO:0003909)
0.0 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.0 0.2 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.2 GO:0033857 diphosphoinositol-pentakisphosphate kinase activity(GO:0033857)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0032143 single thymine insertion binding(GO:0032143)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.1 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.1 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0017089 glycolipid transporter activity(GO:0017089)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.0 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.1 GO:1990450 linear polyubiquitin binding(GO:1990450)
0.0 0.0 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.0 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.0 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.1 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.0 GO:0001884 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.0 0.1 GO:0052842 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID ATM PATHWAY ATM pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint