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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for GFI1B

Z-value: 1.00

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Transcription factors associated with GFI1B

Gene Symbol Gene ID Gene Info
GFI1B
ENSG00000165702.8 growth factor independent 1B transcriptional repressor

Activity profile of GFI1B motif

Sorted Z-values of GFI1B motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_149689066 1.02 ENST00000593416.1
AC117395.1
LOC646903 protein; Uncharacterized protein
chr12_-_53601000 0.80 ENST00000338737.4
ENST00000549086.2
ITGB7
integrin, beta 7
chr12_-_53601055 0.65 ENST00000552972.1
ENST00000422257.3
ENST00000267082.5
ITGB7
integrin, beta 7
chr7_-_150721570 0.62 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
ATG9B
autophagy related 9B
chr1_+_74663896 0.48 ENST00000370898.3
ENST00000467578.2
ENST00000370894.5
ENST00000482102.2
ENST00000609362.1
ENST00000534056.1
ENST00000557284.2
ENST00000370899.3
ENST00000370895.1
ENST00000534632.1
ENST00000370893.1
ENST00000370891.2
FPGT
FPGT-TNNI3K
TNNI3K
fucose-1-phosphate guanylyltransferase
FPGT-TNNI3K readthrough
TNNI3 interacting kinase
chr9_-_95055923 0.47 ENST00000430417.1
IARS
isoleucyl-tRNA synthetase
chr1_+_164528866 0.45 ENST00000420696.2
PBX1
pre-B-cell leukemia homeobox 1
chr3_-_100551141 0.45 ENST00000478235.1
ENST00000471901.1
ABI3BP
ABI family, member 3 (NESH) binding protein
chr5_-_142077569 0.42 ENST00000407758.1
ENST00000441680.2
ENST00000419524.2
FGF1
fibroblast growth factor 1 (acidic)
chr6_-_56707943 0.41 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST
dystonin
chr11_-_94964354 0.41 ENST00000536441.1
SESN3
sestrin 3
chr22_-_24241117 0.38 ENST00000406213.1
AP000350.4
Uncharacterized protein
chr1_+_164529004 0.38 ENST00000559240.1
ENST00000367897.1
ENST00000540236.1
ENST00000401534.1
PBX1
pre-B-cell leukemia homeobox 1
chr14_-_68157084 0.34 ENST00000557564.1
RP11-1012A1.4
RP11-1012A1.4
chr1_+_95616933 0.34 ENST00000604203.1
RP11-57H12.6
TMEM56-RWDD3 readthrough
chr2_+_9563769 0.34 ENST00000475482.1
CPSF3
cleavage and polyadenylation specific factor 3, 73kDa
chr7_+_79765071 0.33 ENST00000457358.2
GNAI1
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 1
chr6_+_90272488 0.32 ENST00000485637.1
ENST00000522705.1
ANKRD6
ankyrin repeat domain 6
chr12_-_6602955 0.32 ENST00000543703.1
MRPL51
mitochondrial ribosomal protein L51
chr11_+_101785727 0.32 ENST00000263468.8
KIAA1377
KIAA1377
chr4_+_108852697 0.32 ENST00000508453.1
CYP2U1
cytochrome P450, family 2, subfamily U, polypeptide 1
chr12_+_44229846 0.32 ENST00000551577.1
ENST00000266534.3
TMEM117
transmembrane protein 117
chr13_-_76111945 0.31 ENST00000355801.4
ENST00000406936.3
COMMD6
COMM domain containing 6
chr16_+_68279256 0.31 ENST00000564827.2
ENST00000566188.1
ENST00000444212.2
ENST00000568082.1
PLA2G15
phospholipase A2, group XV
chr11_-_7961141 0.30 ENST00000360759.3
OR10A3
olfactory receptor, family 10, subfamily A, member 3
chr15_-_38519066 0.30 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
RP11-346D14.1
chr4_-_68620053 0.30 ENST00000420975.2
ENST00000226413.4
GNRHR
gonadotropin-releasing hormone receptor
chr5_-_64920115 0.29 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr11_+_5617330 0.28 ENST00000278302.5
ENST00000424369.1
ENST00000507320.1
ENST00000380107.1
TRIM6
tripartite motif containing 6
chr15_-_90456156 0.28 ENST00000357484.5
C15orf38
chromosome 15 open reading frame 38
chr11_+_5618029 0.28 ENST00000515022.1
ENST00000506134.1
TRIM6
tripartite motif containing 6
chr11_+_74699703 0.28 ENST00000529024.1
ENST00000544263.1
NEU3
sialidase 3 (membrane sialidase)
chr7_+_66800928 0.28 ENST00000430244.1
RP11-166O4.5
RP11-166O4.5
chr14_-_73360796 0.27 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3
D4, zinc and double PHD fingers, family 3
chr5_-_139930713 0.27 ENST00000602657.1
SRA1
steroid receptor RNA activator 1
chr6_-_56708459 0.27 ENST00000370788.2
DST
dystonin
chr5_-_137475071 0.26 ENST00000265191.2
NME5
NME/NM23 family member 5
chr7_-_112579673 0.26 ENST00000432572.1
C7orf60
chromosome 7 open reading frame 60
chr6_-_88411911 0.26 ENST00000257787.5
AKIRIN2
akirin 2
chr4_-_113627966 0.26 ENST00000505632.1
RP11-148B6.2
RP11-148B6.2
chr13_-_27745936 0.26 ENST00000282344.6
USP12
ubiquitin specific peptidase 12
chr1_+_45792541 0.25 ENST00000334815.3
HPDL
4-hydroxyphenylpyruvate dioxygenase-like
chr1_-_45965525 0.25 ENST00000488405.2
ENST00000490551.3
ENST00000432082.1
CCDC163P
coiled-coil domain containing 163, pseudogene
chr11_+_27076764 0.25 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr12_-_70093235 0.25 ENST00000266661.4
BEST3
bestrophin 3
chr13_+_98795664 0.24 ENST00000376581.5
FARP1
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)
chr1_-_209741018 0.24 ENST00000424696.2
RP1-272L16.1
RP1-272L16.1
chr14_-_53417732 0.24 ENST00000399304.3
ENST00000395631.2
ENST00000341590.3
ENST00000343279.4
FERMT2
fermitin family member 2
chr1_-_94703118 0.24 ENST00000260526.6
ENST00000370217.3
ARHGAP29
Rho GTPase activating protein 29
chr6_+_90192974 0.24 ENST00000520458.1
ANKRD6
ankyrin repeat domain 6
chr1_+_23953817 0.24 ENST00000374555.3
MDS2
myelodysplastic syndrome 2 translocation associated
chr1_-_115301235 0.24 ENST00000525878.1
CSDE1
cold shock domain containing E1, RNA-binding
chr16_+_12995468 0.23 ENST00000424107.3
ENST00000558583.1
ENST00000558318.1
SHISA9
shisa family member 9
chr6_+_71123107 0.23 ENST00000370479.3
ENST00000505769.1
ENST00000515323.1
ENST00000515280.1
ENST00000507085.1
ENST00000457062.2
ENST00000361499.3
FAM135A
family with sequence similarity 135, member A
chr5_-_124080203 0.23 ENST00000504926.1
ZNF608
zinc finger protein 608
chr18_+_11857439 0.23 ENST00000602628.1
GNAL
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
chr6_+_46620705 0.23 ENST00000452689.2
SLC25A27
solute carrier family 25, member 27
chr17_-_19281203 0.22 ENST00000487415.2
B9D1
B9 protein domain 1
chr4_+_48807155 0.22 ENST00000504654.1
OCIAD1
OCIA domain containing 1
chr2_+_29341037 0.22 ENST00000449202.1
CLIP4
CAP-GLY domain containing linker protein family, member 4
chr4_-_176733897 0.22 ENST00000393658.2
GPM6A
glycoprotein M6A
chr21_-_43916296 0.22 ENST00000398352.3
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr4_+_41362796 0.22 ENST00000508501.1
ENST00000512946.1
ENST00000313860.7
ENST00000512632.1
ENST00000512820.1
LIMCH1
LIM and calponin homology domains 1
chr16_-_69385681 0.22 ENST00000288025.3
TMED6
transmembrane emp24 protein transport domain containing 6
chr4_+_15471489 0.21 ENST00000424120.1
ENST00000413206.1
ENST00000438599.2
ENST00000511544.1
ENST00000512702.1
ENST00000507954.1
ENST00000515124.1
ENST00000503292.1
ENST00000503658.1
CC2D2A
coiled-coil and C2 domain containing 2A
chr11_+_71791849 0.21 ENST00000423494.2
ENST00000539587.1
ENST00000538478.1
ENST00000324866.7
ENST00000439209.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr19_+_17337473 0.21 ENST00000598068.1
OCEL1
occludin/ELL domain containing 1
chr14_-_64194745 0.21 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr2_-_158732340 0.21 ENST00000539637.1
ENST00000413751.1
ENST00000434821.1
ENST00000424669.1
ACVR1
activin A receptor, type I
chr15_-_70994612 0.21 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr1_-_173638976 0.21 ENST00000333279.2
ANKRD45
ankyrin repeat domain 45
chr11_+_5617976 0.21 ENST00000445329.1
TRIM6
tripartite motif containing 6
chr7_+_120591170 0.20 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr17_-_48133054 0.20 ENST00000499842.1
RP11-1094H24.4
RP11-1094H24.4
chr1_+_92764522 0.20 ENST00000610020.1
RPAP2
RNA polymerase II associated protein 2
chr4_-_156875003 0.20 ENST00000433477.3
CTSO
cathepsin O
chr1_-_68698197 0.20 ENST00000370973.2
ENST00000370971.1
WLS
wntless Wnt ligand secretion mediator
chr1_-_179834311 0.20 ENST00000553856.1
IFRG15
Homo sapiens torsin A interacting protein 2 (TOR1AIP2), transcript variant 1, mRNA.
chr4_-_112993808 0.20 ENST00000511219.1
RP11-269F21.3
RP11-269F21.3
chr1_+_109102652 0.20 ENST00000370035.3
ENST00000405454.1
FAM102B
family with sequence similarity 102, member B
chr18_+_77905894 0.19 ENST00000589574.1
ENST00000588226.1
ENST00000585422.1
AC139100.2
Uncharacterized protein
chr1_-_68698222 0.19 ENST00000370976.3
ENST00000354777.2
ENST00000262348.4
ENST00000540432.1
WLS
wntless Wnt ligand secretion mediator
chr8_-_6420759 0.19 ENST00000523120.1
ANGPT2
angiopoietin 2
chr12_+_32638897 0.19 ENST00000531134.1
FGD4
FYVE, RhoGEF and PH domain containing 4
chr1_-_47134085 0.19 ENST00000371937.4
ENST00000574428.1
ENST00000329231.4
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr1_-_23886285 0.19 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr2_-_45236540 0.19 ENST00000303077.6
SIX2
SIX homeobox 2
chr5_+_36608422 0.18 ENST00000381918.3
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr20_-_35274548 0.18 ENST00000262866.4
SLA2
Src-like-adaptor 2
chrX_+_119737806 0.18 ENST00000371317.5
MCTS1
malignant T cell amplified sequence 1
chr1_+_35544968 0.18 ENST00000359858.4
ENST00000373330.1
ZMYM1
zinc finger, MYM-type 1
chr1_+_101702417 0.18 ENST00000305352.6
S1PR1
sphingosine-1-phosphate receptor 1
chr19_+_21264943 0.18 ENST00000597424.1
ZNF714
zinc finger protein 714
chr10_+_70980051 0.18 ENST00000354624.5
ENST00000395086.2
HKDC1
hexokinase domain containing 1
chr1_+_164528616 0.18 ENST00000340699.3
PBX1
pre-B-cell leukemia homeobox 1
chr4_+_78829479 0.18 ENST00000504901.1
MRPL1
mitochondrial ribosomal protein L1
chr1_-_92764523 0.17 ENST00000370360.3
ENST00000534881.1
GLMN
glomulin, FKBP associated protein
chr16_+_68279207 0.17 ENST00000413021.2
ENST00000565744.1
ENST00000219345.5
PLA2G15
phospholipase A2, group XV
chr8_-_10987745 0.17 ENST00000400102.3
AF131215.5
AF131215.5
chrX_+_49832231 0.17 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr17_+_74075263 0.17 ENST00000334586.5
ENST00000392503.2
ZACN
zinc activated ligand-gated ion channel
chr19_+_11455900 0.17 ENST00000588790.1
CCDC159
coiled-coil domain containing 159
chr2_+_47630108 0.17 ENST00000233146.2
ENST00000454849.1
ENST00000543555.1
MSH2
mutS homolog 2
chr14_-_106069247 0.17 ENST00000479229.1
RP11-731F5.1
RP11-731F5.1
chr19_+_21264980 0.17 ENST00000596053.1
ENST00000597086.1
ENST00000596143.1
ENST00000596367.1
ENST00000601416.1
ZNF714
zinc finger protein 714
chr18_+_48494361 0.17 ENST00000588577.1
ENST00000269466.3
ENST00000591429.1
ENST00000452201.2
ELAC1
SMAD4
elaC ribonuclease Z 1
SMAD family member 4
chrX_+_129473859 0.17 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr7_+_150758642 0.17 ENST00000488420.1
SLC4A2
solute carrier family 4 (anion exchanger), member 2
chr11_-_85430356 0.17 ENST00000526999.1
SYTL2
synaptotagmin-like 2
chr19_+_9361606 0.17 ENST00000456448.1
OR7E24
olfactory receptor, family 7, subfamily E, member 24
chr19_-_58951496 0.17 ENST00000254166.3
ZNF132
zinc finger protein 132
chr6_-_8435758 0.16 ENST00000426876.1
ENST00000339306.5
SLC35B3
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
chr12_+_117176090 0.16 ENST00000257575.4
ENST00000407967.3
ENST00000392549.2
RNFT2
ring finger protein, transmembrane 2
chr7_+_127233689 0.16 ENST00000265825.5
ENST00000420086.2
FSCN3
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr19_+_51774540 0.16 ENST00000600813.1
CTD-3187F8.11
CTD-3187F8.11
chr11_+_71791693 0.16 ENST00000289488.2
ENST00000447974.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing
chr4_+_26165074 0.16 ENST00000512351.1
RBPJ
recombination signal binding protein for immunoglobulin kappa J region
chr4_+_105828492 0.16 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chr19_-_48823332 0.16 ENST00000315396.7
CCDC114
coiled-coil domain containing 114
chr6_+_107077471 0.16 ENST00000369044.1
QRSL1
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr15_+_65204075 0.16 ENST00000380230.3
ENST00000357698.3
ENST00000395720.1
ENST00000496660.1
ENST00000319580.8
ANKDD1A
ankyrin repeat and death domain containing 1A
chr12_+_124155652 0.16 ENST00000426174.2
ENST00000303372.5
TCTN2
tectonic family member 2
chr9_-_14180778 0.16 ENST00000380924.1
ENST00000543693.1
NFIB
nuclear factor I/B
chr19_-_41934635 0.16 ENST00000321702.2
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr15_-_75918787 0.15 ENST00000564086.1
SNUPN
snurportin 1
chr10_-_129924611 0.15 ENST00000368654.3
MKI67
marker of proliferation Ki-67
chr1_+_15943995 0.15 ENST00000480945.1
DDI2
DNA-damage inducible 1 homolog 2 (S. cerevisiae)
chr4_+_26585538 0.15 ENST00000264866.4
TBC1D19
TBC1 domain family, member 19
chr9_-_95640218 0.15 ENST00000395506.3
ENST00000375495.3
ENST00000332591.6
ZNF484
zinc finger protein 484
chr2_-_132589601 0.15 ENST00000437330.1
AC103564.7
AC103564.7
chr7_+_120590803 0.15 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
ING3
inhibitor of growth family, member 3
chr17_+_46131912 0.15 ENST00000584634.1
ENST00000580050.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr1_+_210406121 0.15 ENST00000367012.3
SERTAD4
SERTA domain containing 4
chr17_+_46132037 0.15 ENST00000582155.1
ENST00000583378.1
ENST00000536222.1
NFE2L1
nuclear factor, erythroid 2-like 1
chr19_+_55417499 0.15 ENST00000291890.4
ENST00000447255.1
ENST00000598576.1
ENST00000594765.1
NCR1
natural cytotoxicity triggering receptor 1
chr20_+_52105495 0.15 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr3_-_18466026 0.15 ENST00000417717.2
SATB1
SATB homeobox 1
chr21_-_42879909 0.15 ENST00000458356.1
ENST00000398585.3
ENST00000424093.1
TMPRSS2
transmembrane protease, serine 2
chr1_-_23751189 0.14 ENST00000374601.3
ENST00000450454.2
TCEA3
transcription elongation factor A (SII), 3
chr5_+_133451254 0.14 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr17_+_79031415 0.14 ENST00000572073.1
ENST00000573677.1
BAIAP2
BAI1-associated protein 2
chr19_-_44388116 0.14 ENST00000587539.1
ZNF404
zinc finger protein 404
chr12_-_95397442 0.14 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr19_-_51412584 0.14 ENST00000431178.2
KLK4
kallikrein-related peptidase 4
chr4_-_10023095 0.14 ENST00000264784.3
SLC2A9
solute carrier family 2 (facilitated glucose transporter), member 9
chr10_-_23633720 0.14 ENST00000323327.4
C10orf67
chromosome 10 open reading frame 67
chr15_-_49255632 0.14 ENST00000332408.4
SHC4
SHC (Src homology 2 domain containing) family, member 4
chr1_-_74663825 0.14 ENST00000370911.3
ENST00000370909.2
ENST00000354431.4
LRRIQ3
leucine-rich repeats and IQ motif containing 3
chr2_+_233404429 0.14 ENST00000389494.3
ENST00000389492.3
CHRNG
cholinergic receptor, nicotinic, gamma (muscle)
chr11_-_46113756 0.14 ENST00000531959.1
PHF21A
PHD finger protein 21A
chrX_-_54069576 0.14 ENST00000445025.1
ENST00000322659.8
PHF8
PHD finger protein 8
chr2_+_158733088 0.14 ENST00000605860.1
UPP2
uridine phosphorylase 2
chr21_-_47743719 0.14 ENST00000397680.1
ENST00000445935.1
ENST00000397685.4
ENST00000397682.3
ENST00000291691.7
C21orf58
chromosome 21 open reading frame 58
chr1_+_33283043 0.14 ENST00000373476.1
ENST00000373475.5
ENST00000529027.1
ENST00000398243.3
S100PBP
S100P binding protein
chrX_-_48056199 0.14 ENST00000311798.1
ENST00000347757.1
SSX5
synovial sarcoma, X breakpoint 5
chr4_+_154125565 0.14 ENST00000338700.5
TRIM2
tripartite motif containing 2
chr3_-_93781750 0.14 ENST00000314636.2
DHFRL1
dihydrofolate reductase-like 1
chr19_+_7069690 0.14 ENST00000439035.2
ZNF557
zinc finger protein 557
chr4_+_76995855 0.13 ENST00000355810.4
ENST00000349321.3
ART3
ADP-ribosyltransferase 3
chr10_-_129924468 0.13 ENST00000368653.3
MKI67
marker of proliferation Ki-67
chr7_+_66093908 0.13 ENST00000443322.1
ENST00000449064.1
KCTD7
potassium channel tetramerization domain containing 7
chr1_+_244816237 0.13 ENST00000302550.11
DESI2
desumoylating isopeptidase 2
chr3_-_149688896 0.13 ENST00000239940.7
PFN2
profilin 2
chr4_+_119606523 0.13 ENST00000388822.5
ENST00000506780.1
ENST00000508801.1
METTL14
methyltransferase like 14
chr4_+_86748898 0.13 ENST00000509300.1
ARHGAP24
Rho GTPase activating protein 24
chr1_-_197169672 0.13 ENST00000367405.4
ZBTB41
zinc finger and BTB domain containing 41
chr12_+_72061563 0.13 ENST00000551238.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr3_+_119814070 0.13 ENST00000469070.1
RP11-18H7.1
RP11-18H7.1
chr10_-_91403625 0.13 ENST00000322191.6
ENST00000342512.3
ENST00000371774.2
PANK1
pantothenate kinase 1
chr16_+_21623392 0.13 ENST00000562961.1
METTL9
methyltransferase like 9
chr2_-_110371412 0.13 ENST00000415095.1
ENST00000334001.6
ENST00000437928.1
ENST00000493445.1
ENST00000397714.2
ENST00000461295.1
SEPT10
septin 10
chr16_+_15039742 0.13 ENST00000537062.1
NPIPA1
nuclear pore complex interacting protein family, member A1
chr2_-_110371720 0.13 ENST00000356688.4
SEPT10
septin 10
chr5_-_137071756 0.13 ENST00000394937.3
ENST00000309755.4
KLHL3
kelch-like family member 3
chr7_+_134551583 0.13 ENST00000435928.1
CALD1
caldesmon 1
chr2_+_219472637 0.13 ENST00000417849.1
PLCD4
phospholipase C, delta 4
chr6_-_116381918 0.13 ENST00000606080.1
FRK
fyn-related kinase
chr2_-_176033066 0.13 ENST00000437522.1
ATF2
activating transcription factor 2
chr17_+_36858694 0.13 ENST00000563897.1
CTB-58E17.1
CTB-58E17.1
chr15_-_59041768 0.13 ENST00000402627.1
ENST00000396140.2
ENST00000559053.1
ENST00000561288.1
ADAM10
ADAM metallopeptidase domain 10
chr6_-_13621126 0.13 ENST00000600057.1
AL441883.1
Uncharacterized protein
chr14_-_36989427 0.13 ENST00000354822.5
NKX2-1
NK2 homeobox 1
chr2_-_55496344 0.12 ENST00000403721.1
ENST00000263629.4
MTIF2
mitochondrial translational initiation factor 2
chr2_-_110371777 0.12 ENST00000397712.2
SEPT10
septin 10
chr2_-_96874553 0.12 ENST00000337288.5
ENST00000443962.1
STARD7
StAR-related lipid transfer (START) domain containing 7
chr11_-_33774944 0.12 ENST00000532057.1
ENST00000531080.1
FBXO3
F-box protein 3
chr2_-_207078154 0.12 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr1_-_47134101 0.12 ENST00000576409.1
ATPAF1
ATP synthase mitochondrial F1 complex assembly factor 1
chr3_-_49466686 0.12 ENST00000273598.3
ENST00000436744.2
NICN1
nicolin 1
chr4_-_4544061 0.11 ENST00000507908.1
STX18
syntaxin 18
chr6_-_8435706 0.11 ENST00000379660.4
SLC35B3
solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B3
chr4_-_159080806 0.11 ENST00000590648.1
FAM198B
family with sequence similarity 198, member B
chr4_+_105828537 0.11 ENST00000515649.1
RP11-556I14.1
RP11-556I14.1
chr2_+_234104079 0.11 ENST00000417661.1
INPP5D
inositol polyphosphate-5-phosphatase, 145kDa
chr15_-_34331243 0.11 ENST00000306730.3
AVEN
apoptosis, caspase activation inhibitor
chr1_+_202385953 0.11 ENST00000466968.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr1_+_203651937 0.11 ENST00000341360.2
ATP2B4
ATPase, Ca++ transporting, plasma membrane 4
chr21_-_43916433 0.11 ENST00000291536.3
RSPH1
radial spoke head 1 homolog (Chlamydomonas)
chr2_-_85788605 0.11 ENST00000233838.4
GGCX
gamma-glutamyl carboxylase
chr11_+_71791803 0.10 ENST00000539271.1
LRTOMT
leucine rich transmembrane and O-methyltransferase domain containing

Network of associatons between targets according to the STRING database.

First level regulatory network of GFI1B

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 0.5 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 0.4 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.3 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.6 GO:0044805 late nucleophagy(GO:0044805)
0.1 0.4 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.3 GO:0046963 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.1 0.1 GO:0048370 lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371) lateral mesodermal cell fate commitment(GO:0048372) lateral mesodermal cell fate specification(GO:0048377) regulation of lateral mesodermal cell fate specification(GO:0048378)
0.1 0.3 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.8 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.1 0.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.1 0.2 GO:0003245 cardiac muscle tissue growth involved in heart morphogenesis(GO:0003245)
0.1 0.3 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.1 0.2 GO:0035262 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) gonad morphogenesis(GO:0035262)
0.1 0.2 GO:0003274 endocardial cushion fusion(GO:0003274)
0.0 0.2 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.0 0.7 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0061015 snRNA import into nucleus(GO:0061015)
0.0 0.3 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.4 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.4 GO:0097267 omega-hydroxylase P450 pathway(GO:0097267)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.1 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.2 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.0 0.1 GO:1903248 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.4 GO:0035766 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.2 GO:0006311 meiotic gene conversion(GO:0006311) regulation of reciprocal meiotic recombination(GO:0010520)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.3 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.2 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.7 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.3 GO:0070777 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.5 GO:0038203 TORC2 signaling(GO:0038203)
0.0 1.0 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.0 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.1 GO:0046108 uridine metabolic process(GO:0046108)
0.0 0.1 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:0048619 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0050960 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0009820 alkaloid metabolic process(GO:0009820)
0.0 0.1 GO:0060168 positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.1 GO:0097187 dentinogenesis(GO:0097187)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086) pattern specification involved in metanephros development(GO:0072268)
0.0 0.3 GO:1904321 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:1901295 positive regulation of ephrin receptor signaling pathway(GO:1901189) regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.2 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.5 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.2 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.3 GO:0042424 phenol-containing compound catabolic process(GO:0019336) catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0 0.1 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.1 GO:0006433 glutamyl-tRNA aminoacylation(GO:0006424) prolyl-tRNA aminoacylation(GO:0006433)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.0 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:0042713 sperm ejaculation(GO:0042713)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.0 GO:0002933 lipid hydroxylation(GO:0002933)
0.0 0.1 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.0 GO:0003363 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.0 0.2 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.0 GO:1905205 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.0 0.0 GO:1905224 clathrin-coated pit assembly(GO:1905224)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.2 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0035754 B cell chemotaxis(GO:0035754)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.7 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.2 GO:0032302 MutSbeta complex(GO:0032302)
0.1 0.2 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.3 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.1 GO:0016514 SWI/SNF complex(GO:0016514)
0.0 0.6 GO:0036038 MKS complex(GO:0036038)
0.0 0.4 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.7 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.1 GO:0000799 nuclear condensin complex(GO:0000799)
0.0 0.6 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462) Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.3 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.1 0.3 GO:0052794 exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.3 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.1 0.3 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.5 GO:0070568 guanylyltransferase activity(GO:0070568)
0.1 0.2 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.1 0.2 GO:0000406 double-strand/single-strand DNA junction binding(GO:0000406) dinucleotide repeat insertion binding(GO:0032181)
0.0 0.1 GO:0016422 mRNA (2'-O-methyladenosine-N6-)-methyltransferase activity(GO:0016422)
0.0 0.2 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.1 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.0 0.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.1 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.3 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.0 0.5 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685) tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871) 20-hydroxy-leukotriene B4 omega oxidase activity(GO:0097258) 20-aldehyde-leukotriene B4 20-monooxygenase activity(GO:0097259)
0.0 0.3 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.2 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.5 GO:0031628 opioid receptor binding(GO:0031628)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.2 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.2 GO:0008865 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.1 GO:0033265 acetylcholinesterase activity(GO:0003990) choline binding(GO:0033265)
0.0 0.1 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0004827 glutamate-tRNA ligase activity(GO:0004818) proline-tRNA ligase activity(GO:0004827)
0.0 0.4 GO:0070330 aromatase activity(GO:0070330)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.1 GO:0015333 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.2 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.7 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.4 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.0 1.4 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.5 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 1.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors