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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for FOXN1
Z-value: 0.86
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Transcription factors associated with FOXN1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOXN1 | hg19_v2_chr17_+_26833250_26833278 | 0.28 | 5.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_+_54198210 Show fit | 0.45 |
ENST00000607452.1
ENST00000422521.2 |
acylphosphatase 2, muscle type |
|
| chrX_-_108868390 Show fit | 0.43 |
ENST00000372101.2
|
KCNE1-like |
|
| chr14_-_77495007 Show fit | 0.43 |
ENST00000238647.3
|
interferon regulatory factor 2 binding protein-like |
|
| chr2_+_46769798 Show fit | 0.42 |
ENST00000238738.4
|
ras homolog family member Q |
|
| chr2_-_38830030 Show fit | 0.38 |
ENST00000410076.1
|
heterogeneous nuclear ribonucleoprotein L-like |
|
| chrX_-_83442915 Show fit | 0.37 |
ENST00000262752.2
ENST00000543399.1 |
ribosomal protein S6 kinase, 90kDa, polypeptide 6 |
|
| chr19_-_56110859 Show fit | 0.34 |
ENST00000221665.3
ENST00000592585.1 |
FLT3-interacting zinc finger 1 |
|
| chrX_-_106959631 Show fit | 0.32 |
ENST00000486554.1
ENST00000372390.4 |
TSC22 domain family, member 3 |
|
| chr8_+_38243721 Show fit | 0.30 |
ENST00000527334.1
|
leucine zipper-EF-hand containing transmembrane protein 2 |
|
| chrX_+_105969893 Show fit | 0.28 |
ENST00000255499.2
|
ring finger protein 128, E3 ubiquitin protein ligase |
Network of associatons between targets according to the STRING database.
First level regulatory network of FOXN1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | GO:0090005 | negative regulation of establishment of protein localization to plasma membrane(GO:0090005) |
| 0.0 | 0.4 | GO:2000381 | negative regulation of mesoderm development(GO:2000381) |
| 0.0 | 0.4 | GO:0035965 | cardiolipin acyl-chain remodeling(GO:0035965) |
| 0.0 | 0.4 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
| 0.1 | 0.3 | GO:0001828 | inner cell mass cellular morphogenesis(GO:0001828) |
| 0.1 | 0.3 | GO:0051083 | 'de novo' cotranslational protein folding(GO:0051083) |
| 0.0 | 0.3 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.0 | 0.3 | GO:0030916 | otic vesicle formation(GO:0030916) |
| 0.0 | 0.3 | GO:0060155 | platelet dense granule organization(GO:0060155) |
| 0.0 | 0.3 | GO:1904352 | positive regulation of protein catabolic process in the vacuole(GO:1904352) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.5 | GO:0097228 | sperm principal piece(GO:0097228) |
| 0.0 | 0.3 | GO:0000242 | pericentriolar material(GO:0000242) |
| 0.0 | 0.3 | GO:0031083 | BLOC-1 complex(GO:0031083) |
| 0.0 | 0.2 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
| 0.0 | 0.2 | GO:0000931 | gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274) |
| 0.0 | 0.2 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.0 | 0.2 | GO:0005861 | troponin complex(GO:0005861) |
| 0.0 | 0.1 | GO:0044301 | climbing fiber(GO:0044301) |
| 0.0 | 0.1 | GO:0098837 | postsynaptic recycling endosome(GO:0098837) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.5 | GO:0032427 | GBD domain binding(GO:0032427) |
| 0.1 | 0.5 | GO:0003998 | acylphosphatase activity(GO:0003998) |
| 0.0 | 0.4 | GO:0043047 | single-stranded telomeric DNA binding(GO:0043047) |
| 0.0 | 0.4 | GO:0008239 | dipeptidyl-peptidase activity(GO:0008239) |
| 0.0 | 0.4 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
| 0.0 | 0.3 | GO:0043426 | MRF binding(GO:0043426) |
| 0.0 | 0.3 | GO:0008420 | CTD phosphatase activity(GO:0008420) |
| 0.0 | 0.3 | GO:0051011 | microtubule minus-end binding(GO:0051011) |
| 0.1 | 0.2 | GO:0071207 | histone pre-mRNA stem-loop binding(GO:0071207) |
| 0.0 | 0.2 | GO:0047179 | platelet-activating factor acetyltransferase activity(GO:0047179) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 0.2 | REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND | Genes involved in Removal of the Flap Intermediate from the C-strand |
| 0.0 | 0.2 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |