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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Z-value: 0.80

Motif logo

Transcription factors associated with FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

Gene Symbol Gene ID Gene Info
ENSG00000251493.2 FOXD1
ENSG00000150907.6 FOXO1
ENSG00000204060.4 FOXO6
ENSG00000176165.7 FOXG1
ENSG00000114861.14 FOXP1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXO1hg19_v2_chr13_-_41240717_412407350.758.8e-02Click!
FOXD1hg19_v2_chr5_-_72744336_727443590.749.1e-02Click!
FOXP1hg19_v2_chr3_-_71353892_71353928-0.532.8e-01Click!
FOXO6hg19_v2_chr1_+_41827594_418275940.404.3e-01Click!
FOXG1hg19_v2_chr14_+_29236269_29236287-0.157.8e-01Click!

Activity profile of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Sorted Z-values of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXD1_FOXO1_FOXO6_FOXG1_FOXP1

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr3_-_178865747 0.86 ENST00000435560.1
RP11-360P21.2
RP11-360P21.2
chr14_-_54418598 0.81 ENST00000609748.1
ENST00000558961.1
BMP4
bone morphogenetic protein 4
chr7_-_95225768 0.80 ENST00000005178.5
PDK4
pyruvate dehydrogenase kinase, isozyme 4
chr5_-_42811986 0.70 ENST00000511224.1
ENST00000507920.1
ENST00000510965.1
SEPP1
selenoprotein P, plasma, 1
chr17_-_8263538 0.69 ENST00000535173.1
AC135178.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr19_+_12902289 0.60 ENST00000302754.4
JUNB
jun B proto-oncogene
chr17_+_37821593 0.58 ENST00000578283.1
TCAP
titin-cap
chrX_-_55208866 0.58 ENST00000545075.1
MTRNR2L10
MT-RNR2-like 10
chr7_-_84122033 0.58 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr5_-_42812143 0.57 ENST00000514985.1
SEPP1
selenoprotein P, plasma, 1
chrX_-_106960285 0.57 ENST00000503515.1
ENST00000372397.2
TSC22D3
TSC22 domain family, member 3
chr2_+_189157536 0.54 ENST00000409580.1
ENST00000409637.3
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr2_+_198380763 0.53 ENST00000448447.2
ENST00000409360.1
MOB4
MOB family member 4, phocein
chr7_+_134551583 0.53 ENST00000435928.1
CALD1
caldesmon 1
chr12_+_6881678 0.51 ENST00000441671.2
ENST00000203629.2
LAG3
lymphocyte-activation gene 3
chr8_-_8318847 0.49 ENST00000521218.1
CTA-398F10.2
CTA-398F10.2
chr2_+_189157498 0.47 ENST00000359135.3
GULP1
GULP, engulfment adaptor PTB domain containing 1
chr19_-_18391708 0.47 ENST00000600972.1
JUND
jun D proto-oncogene
chr11_+_844406 0.44 ENST00000397404.1
TSPAN4
tetraspanin 4
chr16_+_290181 0.44 ENST00000417499.1
ITFG3
integrin alpha FG-GAP repeat containing 3
chr6_+_74405501 0.44 ENST00000437994.2
ENST00000422508.2
CD109
CD109 molecule
chr5_-_142782862 0.43 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_+_72427477 0.42 ENST00000342648.5
ENST00000481232.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr2_+_111878483 0.41 ENST00000308659.8
ENST00000357757.2
ENST00000393253.2
ENST00000337565.5
ENST00000393256.3
BCL2L11
BCL2-like 11 (apoptosis facilitator)
chr2_+_149402989 0.41 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr14_-_69262789 0.41 ENST00000557022.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr11_+_844067 0.41 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
TSPAN4
tetraspanin 4
chr1_+_33722080 0.40 ENST00000483388.1
ENST00000539719.1
ZNF362
zinc finger protein 362
chr1_-_1356628 0.40 ENST00000442470.1
ENST00000537107.1
ANKRD65
ankyrin repeat domain 65
chr6_+_74405804 0.39 ENST00000287097.5
CD109
CD109 molecule
chr2_+_132479948 0.38 ENST00000355171.4
C2orf27A
chromosome 2 open reading frame 27A
chr6_+_89791507 0.38 ENST00000354922.3
PNRC1
proline-rich nuclear receptor coactivator 1
chr5_+_78532003 0.38 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr17_+_72426891 0.37 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr8_-_95449155 0.37 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr5_+_137673200 0.37 ENST00000434981.2
FAM53C
family with sequence similarity 53, member C
chr1_+_116654376 0.35 ENST00000369500.3
MAB21L3
mab-21-like 3 (C. elegans)
chr13_-_41240717 0.35 ENST00000379561.5
FOXO1
forkhead box O1
chr6_-_134639042 0.35 ENST00000461976.2
SGK1
serum/glucocorticoid regulated kinase 1
chr16_-_4323015 0.34 ENST00000204517.6
TFAP4
transcription factor AP-4 (activating enhancer binding protein 4)
chr1_-_1356719 0.34 ENST00000520296.1
ANKRD65
ankyrin repeat domain 65
chr14_-_69262916 0.33 ENST00000553375.1
ZFP36L1
ZFP36 ring finger protein-like 1
chr7_+_134832808 0.33 ENST00000275767.3
TMEM140
transmembrane protein 140
chr4_+_183370146 0.33 ENST00000510504.1
TENM3
teneurin transmembrane protein 3
chr3_+_178865887 0.33 ENST00000477735.1
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr7_-_112579869 0.32 ENST00000297145.4
C7orf60
chromosome 7 open reading frame 60
chr19_-_45909585 0.32 ENST00000593226.1
ENST00000418234.2
PPP1R13L
protein phosphatase 1, regulatory subunit 13 like
chr14_-_23288930 0.31 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr10_+_23728198 0.31 ENST00000376495.3
OTUD1
OTU domain containing 1
chr4_-_140223670 0.31 ENST00000394228.1
ENST00000539387.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr4_-_140223614 0.31 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr4_-_111120334 0.30 ENST00000503885.1
ELOVL6
ELOVL fatty acid elongase 6
chr16_+_4421841 0.30 ENST00000304735.3
VASN
vasorin
chr7_-_84121858 0.29 ENST00000448879.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr10_+_99079008 0.29 ENST00000371021.3
FRAT1
frequently rearranged in advanced T-cell lymphomas
chr7_+_77469439 0.29 ENST00000450574.1
ENST00000416283.2
ENST00000248550.7
PHTF2
putative homeodomain transcription factor 2
chr5_+_102200948 0.28 ENST00000511477.1
ENST00000506006.1
ENST00000509832.1
PAM
peptidylglycine alpha-amidating monooxygenase
chr5_+_172484377 0.28 ENST00000523161.1
CREBRF
CREB3 regulatory factor
chr16_+_1832902 0.28 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2
nucleotide binding protein 2
chr16_-_4664860 0.28 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBALD1
UBA-like domain containing 1
chr15_+_96869165 0.28 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr5_-_131132614 0.27 ENST00000307968.7
ENST00000307954.8
FNIP1
folliculin interacting protein 1
chr15_-_44828838 0.27 ENST00000560750.1
EIF3J-AS1
EIF3J antisense RNA 1 (head to head)
chr5_-_142065612 0.27 ENST00000360966.5
ENST00000411960.1
FGF1
fibroblast growth factor 1 (acidic)
chr3_+_113616317 0.27 ENST00000440446.2
ENST00000488680.1
GRAMD1C
GRAM domain containing 1C
chr6_-_56707943 0.27 ENST00000370769.4
ENST00000421834.2
ENST00000312431.6
ENST00000361203.3
ENST00000523817.1
DST
dystonin
chr1_+_87797351 0.27 ENST00000370542.1
LMO4
LIM domain only 4
chr14_-_58893876 0.26 ENST00000555097.1
ENST00000555404.1
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr2_-_207078154 0.26 ENST00000447845.1
GPR1
G protein-coupled receptor 1
chr17_+_38333263 0.26 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr7_+_129906660 0.25 ENST00000222481.4
CPA2
carboxypeptidase A2 (pancreatic)
chr14_-_36988882 0.25 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr12_-_78934441 0.25 ENST00000546865.1
ENST00000547089.1
RP11-171L9.1
RP11-171L9.1
chr7_-_112579673 0.25 ENST00000432572.1
C7orf60
chromosome 7 open reading frame 60
chr5_+_133451254 0.25 ENST00000517851.1
ENST00000521639.1
ENST00000522375.1
ENST00000378560.4
ENST00000432532.2
ENST00000520958.1
ENST00000518915.1
ENST00000395023.1
TCF7
transcription factor 7 (T-cell specific, HMG-box)
chr9_-_115095123 0.25 ENST00000458258.1
PTBP3
polypyrimidine tract binding protein 3
chr16_-_4665023 0.25 ENST00000591897.1
UBALD1
UBA-like domain containing 1
chr1_+_24646263 0.25 ENST00000524724.1
GRHL3
grainyhead-like 3 (Drosophila)
chr1_+_84630645 0.25 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr19_+_1205740 0.25 ENST00000326873.7
STK11
serine/threonine kinase 11
chr15_+_81589254 0.25 ENST00000394652.2
IL16
interleukin 16
chrX_+_37865804 0.24 ENST00000297875.2
ENST00000357972.5
SYTL5
synaptotagmin-like 5
chr5_-_137674000 0.24 ENST00000510119.1
ENST00000513970.1
CDC25C
cell division cycle 25C
chr5_-_142783175 0.23 ENST00000231509.3
ENST00000394464.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
chr17_-_8059638 0.22 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
PER1
period circadian clock 1
chr3_+_181429704 0.22 ENST00000431565.2
ENST00000325404.1
SOX2
SRY (sex determining region Y)-box 2
chr4_+_76871883 0.22 ENST00000599764.1
AC110615.1
Uncharacterized protein
chr5_-_131132658 0.22 ENST00000514667.1
ENST00000511848.1
ENST00000510461.1
CTC-432M15.3
FNIP1
Folliculin-interacting protein 1
folliculin interacting protein 1
chr2_-_176033066 0.22 ENST00000437522.1
ATF2
activating transcription factor 2
chr17_+_79369249 0.22 ENST00000574717.2
RP11-1055B8.6
Uncharacterized protein
chr15_-_70994612 0.22 ENST00000558758.1
ENST00000379983.2
ENST00000560441.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr11_-_111781554 0.22 ENST00000526167.1
ENST00000528961.1
CRYAB
crystallin, alpha B
chr18_+_60382672 0.22 ENST00000400316.4
ENST00000262719.5
PHLPP1
PH domain and leucine rich repeat protein phosphatase 1
chr1_-_115259337 0.21 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr10_+_43932553 0.21 ENST00000456416.1
ENST00000437590.2
ENST00000451167.1
ZNF487
zinc finger protein 487
chr14_-_31926701 0.21 ENST00000310850.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr3_+_187930719 0.21 ENST00000312675.4
LPP
LIM domain containing preferred translocation partner in lipoma
chr7_-_83278322 0.21 ENST00000307792.3
SEMA3E
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr18_-_53303123 0.21 ENST00000569357.1
ENST00000565124.1
ENST00000398339.1
TCF4
transcription factor 4
chr6_-_56716686 0.21 ENST00000520645.1
DST
dystonin
chr4_+_90032651 0.21 ENST00000603357.1
RP11-84C13.1
RP11-84C13.1
chr7_+_91570165 0.20 ENST00000356239.3
ENST00000359028.2
ENST00000358100.2
AKAP9
A kinase (PRKA) anchor protein 9
chr2_-_96926313 0.20 ENST00000435268.1
TMEM127
transmembrane protein 127
chr4_-_168155169 0.20 ENST00000534949.1
ENST00000535728.1
SPOCK3
sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
chr20_-_43150601 0.20 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
SERINC3
serine incorporator 3
chr12_+_53491220 0.20 ENST00000548547.1
ENST00000301464.3
IGFBP6
insulin-like growth factor binding protein 6
chr11_-_111781454 0.20 ENST00000533280.1
CRYAB
crystallin, alpha B
chr2_-_152146385 0.20 ENST00000414946.1
ENST00000243346.5
NMI
N-myc (and STAT) interactor
chr17_+_72428266 0.20 ENST00000582473.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr1_-_8586084 0.20 ENST00000464972.1
RERE
arginine-glutamic acid dipeptide (RE) repeats
chr4_+_105828537 0.20 ENST00000515649.1
RP11-556I14.1
RP11-556I14.1
chr8_+_26150628 0.19 ENST00000523925.1
ENST00000315985.7
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr13_+_28712614 0.19 ENST00000380958.3
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr14_+_23067146 0.19 ENST00000428304.2
ABHD4
abhydrolase domain containing 4
chr16_-_84150410 0.19 ENST00000569907.1
MBTPS1
membrane-bound transcription factor peptidase, site 1
chr12_-_76817036 0.19 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr1_-_57431679 0.19 ENST00000371237.4
ENST00000535057.1
ENST00000543257.1
C8B
complement component 8, beta polypeptide
chr11_-_34535297 0.19 ENST00000532417.1
ELF5
E74-like factor 5 (ets domain transcription factor)
chr12_+_48499252 0.19 ENST00000549003.1
ENST00000550924.1
PFKM
phosphofructokinase, muscle
chr5_-_16509101 0.19 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr14_+_56127989 0.19 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chr17_-_29641104 0.19 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr13_-_86373536 0.19 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr3_-_107777208 0.18 ENST00000398258.3
CD47
CD47 molecule
chr3_-_93692681 0.18 ENST00000348974.4
PROS1
protein S (alpha)
chr7_-_105332084 0.18 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr11_-_111781610 0.18 ENST00000525823.1
CRYAB
crystallin, alpha B
chr12_+_54378849 0.18 ENST00000515593.1
HOXC10
homeobox C10
chr17_-_36358166 0.18 ENST00000537432.1
TBC1D3
TBC1 domain family, member 3
chr6_-_42418999 0.18 ENST00000340840.2
ENST00000354325.2
TRERF1
transcriptional regulating factor 1
chr1_+_24646002 0.17 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr1_+_24645807 0.17 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr1_+_227127981 0.17 ENST00000366778.1
ENST00000366777.3
ENST00000458507.2
ADCK3
aarF domain containing kinase 3
chr1_+_24645865 0.17 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr16_+_57680043 0.17 ENST00000569154.1
GPR56
G protein-coupled receptor 56
chr14_+_74551650 0.17 ENST00000554938.1
LIN52
lin-52 homolog (C. elegans)
chr14_+_58894103 0.17 ENST00000354386.6
ENST00000556134.1
KIAA0586
KIAA0586
chr14_-_76447494 0.17 ENST00000238682.3
TGFB3
transforming growth factor, beta 3
chr11_+_46402297 0.17 ENST00000405308.2
MDK
midkine (neurite growth-promoting factor 2)
chr1_-_152297679 0.17 ENST00000368799.1
FLG
filaggrin
chr5_-_64920115 0.16 ENST00000381018.3
ENST00000274327.7
TRIM23
tripartite motif containing 23
chr2_-_233877912 0.16 ENST00000264051.3
NGEF
neuronal guanine nucleotide exchange factor
chrX_-_10851762 0.16 ENST00000380785.1
ENST00000380787.1
MID1
midline 1 (Opitz/BBB syndrome)
chr17_+_67410832 0.16 ENST00000590474.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr19_+_50380917 0.16 ENST00000535102.2
TBC1D17
TBC1 domain family, member 17
chr3_+_193853927 0.16 ENST00000232424.3
HES1
hes family bHLH transcription factor 1
chrX_+_9880412 0.16 ENST00000418909.2
SHROOM2
shroom family member 2
chr18_-_53257027 0.15 ENST00000568740.1
ENST00000564403.2
ENST00000537578.1
TCF4
transcription factor 4
chr12_+_12764773 0.15 ENST00000228865.2
CREBL2
cAMP responsive element binding protein-like 2
chr14_+_32547434 0.15 ENST00000556191.1
ENST00000554090.1
ARHGAP5
Rho GTPase activating protein 5
chr9_+_131904233 0.15 ENST00000432651.1
ENST00000435132.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr15_-_31283618 0.15 ENST00000563714.1
MTMR10
myotubularin related protein 10
chr19_+_13134772 0.15 ENST00000587760.1
ENST00000585575.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr4_+_105828492 0.15 ENST00000506148.1
RP11-556I14.1
RP11-556I14.1
chr1_-_12679171 0.15 ENST00000606790.1
RP11-474O21.5
RP11-474O21.5
chr17_-_29641084 0.15 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr14_-_36989336 0.15 ENST00000522719.2
NKX2-1
NK2 homeobox 1
chr7_-_27179814 0.15 ENST00000522788.1
ENST00000521779.1
HOXA3
homeobox A3
chr19_+_12944722 0.15 ENST00000591495.1
MAST1
microtubule associated serine/threonine kinase 1
chr5_+_137673945 0.15 ENST00000513056.1
ENST00000511276.1
FAM53C
family with sequence similarity 53, member C
chr11_-_72504637 0.15 ENST00000536377.1
ENST00000359373.5
STARD10
ARAP1
StAR-related lipid transfer (START) domain containing 10
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr8_+_99956662 0.15 ENST00000523368.1
ENST00000297565.4
ENST00000435298.2
OSR2
odd-skipped related transciption factor 2
chr1_+_111682058 0.15 ENST00000545121.1
CEPT1
choline/ethanolamine phosphotransferase 1
chr3_-_123339418 0.15 ENST00000583087.1
MYLK
myosin light chain kinase
chr4_+_108746282 0.14 ENST00000503862.1
SGMS2
sphingomyelin synthase 2
chr9_+_131903916 0.14 ENST00000419582.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr10_-_46089939 0.14 ENST00000453980.3
MARCH8
membrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
chr2_-_214014959 0.14 ENST00000442445.1
ENST00000457361.1
ENST00000342002.2
IKZF2
IKAROS family zinc finger 2 (Helios)
chr5_-_126409159 0.14 ENST00000607731.1
ENST00000535381.1
ENST00000296662.5
ENST00000509733.3
C5orf63
chromosome 5 open reading frame 63
chr18_-_53070913 0.14 ENST00000568186.1
ENST00000564228.1
TCF4
transcription factor 4
chr1_-_45956800 0.14 ENST00000538496.1
TESK2
testis-specific kinase 2
chr1_+_92545862 0.14 ENST00000370382.3
ENST00000342818.3
BTBD8
BTB (POZ) domain containing 8
chr7_-_17980091 0.14 ENST00000409389.1
ENST00000409604.1
ENST00000428135.3
SNX13
sorting nexin 13
chr19_+_41725140 0.14 ENST00000359092.3
AXL
AXL receptor tyrosine kinase
chr19_+_18496957 0.14 ENST00000252809.3
GDF15
growth differentiation factor 15
chr1_-_116383322 0.14 ENST00000429731.1
NHLH2
nescient helix loop helix 2
chr6_+_27777819 0.14 ENST00000369163.2
HIST1H3H
histone cluster 1, H3h
chr2_+_175260451 0.14 ENST00000458563.1
ENST00000409673.3
ENST00000272732.6
ENST00000435964.1
SCRN3
secernin 3
chr11_+_46402482 0.13 ENST00000441869.1
MDK
midkine (neurite growth-promoting factor 2)
chr15_+_44719996 0.13 ENST00000559793.1
ENST00000558968.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr3_+_147657764 0.13 ENST00000467198.1
ENST00000485006.1
RP11-71N10.1
RP11-71N10.1
chr14_+_58894141 0.13 ENST00000423743.3
KIAA0586
KIAA0586
chr1_-_12677714 0.13 ENST00000376223.2
DHRS3
dehydrogenase/reductase (SDR family) member 3
chr4_-_40632844 0.13 ENST00000505414.1
RBM47
RNA binding motif protein 47
chr1_-_151813033 0.13 ENST00000454109.1
C2CD4D
C2 calcium-dependent domain containing 4D
chr2_-_214016314 0.13 ENST00000434687.1
ENST00000374319.4
IKZF2
IKAROS family zinc finger 2 (Helios)
chr9_+_136287444 0.13 ENST00000355699.2
ENST00000356589.2
ENST00000371911.3
ADAMTS13
ADAM metallopeptidase with thrombospondin type 1 motif, 13
chr6_+_139094657 0.13 ENST00000332797.6
CCDC28A
coiled-coil domain containing 28A
chr9_-_35754253 0.13 ENST00000436428.2
MSMP
microseminoprotein, prostate associated
chr2_+_173724771 0.13 ENST00000538974.1
ENST00000540783.1
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr1_+_171154347 0.13 ENST00000209929.7
ENST00000441535.1
FMO2
flavin containing monooxygenase 2 (non-functional)
chr10_-_92681033 0.13 ENST00000371697.3
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr10_-_13570533 0.13 ENST00000396900.2
ENST00000396898.2
BEND7
BEN domain containing 7
chr3_-_93692781 0.13 ENST00000394236.3
PROS1
protein S (alpha)
chr9_-_136933615 0.13 ENST00000371834.2
BRD3
bromodomain containing 3
chr16_+_57679859 0.13 ENST00000569494.1
ENST00000566169.1
GPR56
G protein-coupled receptor 56
chr3_+_172468749 0.13 ENST00000366254.2
ENST00000415665.1
ENST00000438041.1
ECT2
epithelial cell transforming sequence 2 oncogene
chr16_+_57680811 0.13 ENST00000569101.1
GPR56
G protein-coupled receptor 56
chr16_-_3422283 0.13 ENST00000399974.3
MTRNR2L4
MT-RNR2-like 4
chr3_-_168865522 0.13 ENST00000464456.1
MECOM
MDS1 and EVI1 complex locus

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.2 0.6 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.2 0.8 GO:0061155 apoptotic process involved in endocardial cushion morphogenesis(GO:0003277) intermediate mesoderm morphogenesis(GO:0048390) intermediate mesoderm formation(GO:0048391) intermediate mesodermal cell differentiation(GO:0048392) regulation of cardiac muscle fiber development(GO:0055018) positive regulation of cardiac muscle fiber development(GO:0055020) bud dilation involved in lung branching(GO:0060503) BMP signaling pathway involved in ureter morphogenesis(GO:0061149) renal system segmentation(GO:0061150) BMP signaling pathway involved in renal system segmentation(GO:0061151) pulmonary artery endothelial tube morphogenesis(GO:0061155) regulation of transcription from RNA polymerase II promoter involved in mesonephros development(GO:0061216) BMP signaling pathway involved in nephric duct formation(GO:0071893) negative regulation of branch elongation involved in ureteric bud branching(GO:0072096) negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway(GO:0072097) anterior/posterior pattern specification involved in ureteric bud development(GO:0072099) specification of ureteric bud anterior/posterior symmetry(GO:0072100) specification of ureteric bud anterior/posterior symmetry by BMP signaling pathway(GO:0072101) ureter epithelial cell differentiation(GO:0072192) negative regulation of mesenchymal cell proliferation involved in ureter development(GO:0072200) positive regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901964) cardiac jelly development(GO:1905072) regulation of metanephric S-shaped body morphogenesis(GO:2000004) negative regulation of metanephric S-shaped body morphogenesis(GO:2000005) regulation of metanephric comma-shaped body morphogenesis(GO:2000006) negative regulation of metanephric comma-shaped body morphogenesis(GO:2000007)
0.1 0.7 GO:0097403 cellular response to raffinose(GO:0097403) response to raffinose(GO:1901545)
0.1 0.4 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.9 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.1 0.5 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.1 0.4 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.4 GO:0010157 response to chlorate(GO:0010157)
0.1 0.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.2 GO:0008057 eye pigment granule organization(GO:0008057)
0.1 0.2 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830) positive regulation of intracellular transport of viral material(GO:1901254)
0.1 0.6 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.3 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 1.0 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.2 GO:0010159 specification of organ position(GO:0010159)
0.1 0.2 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.1 0.3 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.1 0.2 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.2 GO:0042704 detection of oxygen(GO:0003032) uterine wall breakdown(GO:0042704)
0.1 0.2 GO:0035910 inhibition of neuroepithelial cell differentiation(GO:0002085) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) negative regulation of auditory receptor cell differentiation(GO:0045608) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.2 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.1 0.3 GO:0030421 defecation(GO:0030421)
0.0 0.3 GO:0018032 protein amidation(GO:0018032)
0.0 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0045354 interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354)
0.0 0.4 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.0 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 0.3 GO:0071461 cellular response to redox state(GO:0071461)
0.0 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.8 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.3 GO:0048619 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.0 0.3 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.0 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.2 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0 0.9 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.3 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.2 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.4 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0035623 renal glucose absorption(GO:0035623)
0.0 0.2 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.2 GO:0002870 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.2 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 0.3 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0001714 endodermal cell fate specification(GO:0001714)
0.0 0.3 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.0 0.1 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.0 0.1 GO:1900047 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.3 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0035711 plasmacytoid dendritic cell activation(GO:0002270) regulation of restriction endodeoxyribonuclease activity(GO:0032072) T-helper 1 cell activation(GO:0035711)
0.0 0.2 GO:0044211 CTP salvage(GO:0044211)
0.0 0.1 GO:0030037 actin filament reorganization involved in cell cycle(GO:0030037)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.2 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) neural crest cell migration involved in autonomic nervous system development(GO:1901166)
0.0 0.1 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.9 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.3 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.0 0.2 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.1 GO:2000638 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.2 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0035864 response to potassium ion(GO:0035864)
0.0 0.0 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.0 GO:1901985 positive regulation of protein acetylation(GO:1901985)
0.0 0.1 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.2 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.0 0.1 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.3 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.0 0.1 GO:0015887 biotin transport(GO:0015878) pantothenate transmembrane transport(GO:0015887)
0.0 0.1 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.2 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.3 GO:1904886 beta-catenin destruction complex disassembly(GO:1904886)
0.0 0.1 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.0 1.2 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.0 0.1 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.0 0.0 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.0 GO:0007468 regulation of rhodopsin gene expression(GO:0007468) positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988) histone H2A phosphorylation(GO:1990164)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.0 GO:0033122 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.0 GO:1905069 allantois development(GO:1905069)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.1 GO:0060264 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.0 GO:0010430 fatty acid omega-oxidation(GO:0010430)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0035976 AP1 complex(GO:0035976)
0.1 0.2 GO:0036398 TCR signalosome(GO:0036398)
0.1 0.5 GO:0031673 H zone(GO:0031673)
0.1 0.2 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.2 GO:0031251 PAN complex(GO:0031251)
0.0 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.7 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.6 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.2 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 0.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.6 GO:0051373 FATZ binding(GO:0051373)
0.1 0.3 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.8 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 0.5 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 0.2 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 0.8 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0005119 smoothened binding(GO:0005119)
0.1 0.2 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.1 1.1 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0004598 peptidylglycine monooxygenase activity(GO:0004504) peptidylamidoglycolate lyase activity(GO:0004598)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.2 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.4 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004307 diacylglycerol cholinephosphotransferase activity(GO:0004142) ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062) collagen receptor activity(GO:0038064)
0.0 0.6 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 1.2 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.4 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.3 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.0 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.0 0.1 GO:0055077 gap junction hemi-channel activity(GO:0055077)
0.0 0.1 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.0 0.1 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.0 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.4 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.0 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0008523 sodium-dependent multivitamin transmembrane transporter activity(GO:0008523)
0.0 0.0 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.0 0.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.0 GO:0004031 aldehyde oxidase activity(GO:0004031)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.1 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID GMCSF PATHWAY GMCSF-mediated signaling events
0.0 1.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.7 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 1.0 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.6 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade