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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOXA2_FOXJ3

Z-value: 0.71

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Transcription factors associated with FOXA2_FOXJ3

Gene Symbol Gene ID Gene Info
FOXA2
ENSG00000125798.10 forkhead box A2
FOXJ3
ENSG00000198815.4 forkhead box J3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOXA2hg19_v2_chr20_-_22565101_22565223-0.345.1e-01Click!
FOXJ3hg19_v2_chr1_-_42800860_428009120.059.3e-01Click!

Activity profile of FOXA2_FOXJ3 motif

Sorted Z-values of FOXA2_FOXJ3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_72129806 0.73 ENST00000413945.1
ENST00000602878.1
ENST00000436803.1
ENST00000421704.1
ENST00000441570.1
LINC00472
long intergenic non-protein coding RNA 472
chr2_+_58655461 0.57 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
AC007092.1
long intergenic non-protein coding RNA 1122
chr10_-_4285835 0.54 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr6_-_152623231 0.52 ENST00000540663.1
ENST00000537033.1
SYNE1
spectrin repeat containing, nuclear envelope 1
chr1_-_246729544 0.34 ENST00000544618.1
ENST00000366514.4
TFB2M
transcription factor B2, mitochondrial
chr12_-_12714006 0.33 ENST00000541207.1
DUSP16
dual specificity phosphatase 16
chr16_+_28857916 0.32 ENST00000563591.1
SH2B1
SH2B adaptor protein 1
chr5_+_61708488 0.31 ENST00000505902.1
IPO11
importin 11
chr12_-_15038779 0.29 ENST00000228938.5
ENST00000539261.1
MGP
matrix Gla protein
chr6_+_122793058 0.27 ENST00000392491.2
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr10_-_4285923 0.27 ENST00000418372.1
ENST00000608792.1
LINC00702
long intergenic non-protein coding RNA 702
chr12_-_106480587 0.26 ENST00000548902.1
NUAK1
NUAK family, SNF1-like kinase, 1
chr6_+_161123270 0.25 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG
plasminogen
chr12_-_12714025 0.24 ENST00000539940.1
DUSP16
dual specificity phosphatase 16
chr12_-_92539614 0.24 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr1_-_161193349 0.24 ENST00000469730.2
ENST00000463273.1
ENST00000464492.1
ENST00000367990.3
ENST00000470459.2
ENST00000468465.1
ENST00000463812.1
APOA2
apolipoprotein A-II
chr17_-_57229155 0.24 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr6_+_26217159 0.24 ENST00000303910.2
HIST1H2AE
histone cluster 1, H2ae
chr19_+_782755 0.24 ENST00000606242.1
ENST00000586061.1
AC006273.5
AC006273.5
chr2_+_88047606 0.23 ENST00000359481.4
PLGLB2
plasminogen-like B2
chr3_-_48956818 0.23 ENST00000408959.2
ARIH2OS
ariadne homolog 2 opposite strand
chr19_+_16607122 0.23 ENST00000221671.3
ENST00000594035.1
ENST00000599550.1
ENST00000594813.1
C19orf44
chromosome 19 open reading frame 44
chr17_+_67590125 0.23 ENST00000591334.1
AC003051.1
AC003051.1
chr12_+_57998400 0.23 ENST00000548804.1
ENST00000550596.1
ENST00000551835.1
ENST00000549583.1
DTX3
deltex homolog 3 (Drosophila)
chr2_+_162165038 0.20 ENST00000437630.1
PSMD14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr18_+_68002675 0.20 ENST00000584919.1
RP11-41O4.1
Uncharacterized protein
chrX_+_9431324 0.20 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X
transducin (beta)-like 1X-linked
chr4_+_104346194 0.20 ENST00000510200.1
RP11-328K4.1
RP11-328K4.1
chr16_-_21442874 0.19 ENST00000534903.1
NPIPB3
nuclear pore complex interacting protein family, member B3
chr1_+_92545862 0.19 ENST00000370382.3
ENST00000342818.3
BTBD8
BTB (POZ) domain containing 8
chr19_-_8373173 0.19 ENST00000537716.2
ENST00000301458.5
CD320
CD320 molecule
chr12_+_59989918 0.19 ENST00000547379.1
ENST00000549465.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr3_-_135916073 0.19 ENST00000481989.1
MSL2
male-specific lethal 2 homolog (Drosophila)
chr10_+_33271469 0.19 ENST00000414157.1
RP11-462L8.1
RP11-462L8.1
chr2_+_66918558 0.18 ENST00000435389.1
ENST00000428590.1
ENST00000412944.1
AC007392.3
AC007392.3
chr12_+_28605426 0.18 ENST00000542801.1
CCDC91
coiled-coil domain containing 91
chr2_+_143635222 0.17 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
KYNU
kynureninase
chr17_+_41561317 0.16 ENST00000540306.1
ENST00000262415.3
ENST00000605777.1
DHX8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr17_-_6915616 0.16 ENST00000575889.1
AC027763.2
Uncharacterized protein
chr5_-_150460539 0.16 ENST00000520931.1
ENST00000520695.1
ENST00000521591.1
ENST00000518977.1
TNIP1
TNFAIP3 interacting protein 1
chr1_-_114430169 0.15 ENST00000393316.3
BCL2L15
BCL2-like 15
chr2_+_143635067 0.15 ENST00000264170.4
KYNU
kynureninase
chr1_-_207095324 0.15 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr1_+_66796401 0.15 ENST00000528771.1
PDE4B
phosphodiesterase 4B, cAMP-specific
chr1_+_150122034 0.15 ENST00000025469.6
ENST00000369124.4
PLEKHO1
pleckstrin homology domain containing, family O member 1
chr8_+_103540983 0.15 ENST00000523572.1
KB-1980E6.3
Uncharacterized protein
chr16_-_88772670 0.14 ENST00000562544.1
RNF166
ring finger protein 166
chr1_-_203273676 0.13 ENST00000425698.1
RP11-134P9.1
long intergenic non-protein coding RNA 1136
chr17_-_26662440 0.13 ENST00000578122.1
IFT20
intraflagellar transport 20 homolog (Chlamydomonas)
chr19_-_52307357 0.13 ENST00000594900.1
FPR1
formyl peptide receptor 1
chr5_+_136070614 0.13 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr12_+_49297899 0.13 ENST00000552942.1
ENST00000320516.4
CCDC65
coiled-coil domain containing 65
chr4_+_154622652 0.13 ENST00000260010.6
TLR2
toll-like receptor 2
chr17_+_26662679 0.13 ENST00000578158.1
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr5_-_115872124 0.13 ENST00000515009.1
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr12_-_7596735 0.12 ENST00000416109.2
ENST00000396630.1
ENST00000313599.3
CD163L1
CD163 molecule-like 1
chr15_+_90735145 0.12 ENST00000559792.1
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr15_+_64680003 0.12 ENST00000261884.3
TRIP4
thyroid hormone receptor interactor 4
chr3_+_171561127 0.12 ENST00000334567.5
ENST00000450693.1
TMEM212
transmembrane protein 212
chr16_+_22517166 0.12 ENST00000356156.3
NPIPB5
nuclear pore complex interacting protein family, member B5
chr2_+_162272605 0.12 ENST00000389554.3
TBR1
T-box, brain, 1
chr13_-_99910673 0.12 ENST00000397473.2
ENST00000397470.2
GPR18
G protein-coupled receptor 18
chr2_+_12857043 0.11 ENST00000381465.2
TRIB2
tribbles pseudokinase 2
chr1_-_43855444 0.11 ENST00000372455.4
MED8
mediator complex subunit 8
chr6_-_26216872 0.11 ENST00000244601.3
HIST1H2BG
histone cluster 1, H2bg
chr8_+_67104323 0.11 ENST00000518412.1
ENST00000518035.1
ENST00000517725.1
LINC00967
long intergenic non-protein coding RNA 967
chr7_+_106809406 0.11 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1
HMG-box transcription factor 1
chr4_+_117220016 0.11 ENST00000604093.1
MTRNR2L13
MT-RNR2-like 13 (pseudogene)
chr19_+_36132631 0.11 ENST00000379026.2
ENST00000379023.4
ENST00000402764.2
ENST00000479824.1
ETV2
ets variant 2
chr7_+_76107444 0.11 ENST00000435861.1
DTX2
deltex homolog 2 (Drosophila)
chr15_-_40398812 0.10 ENST00000561360.1
BMF
Bcl2 modifying factor
chr1_-_89736434 0.10 ENST00000370459.3
GBP5
guanylate binding protein 5
chr11_+_65851443 0.10 ENST00000533756.1
PACS1
phosphofurin acidic cluster sorting protein 1
chr7_+_76090993 0.10 ENST00000425780.1
ENST00000456590.1
ENST00000451769.1
ENST00000324432.5
ENST00000307569.8
ENST00000457529.1
ENST00000446600.1
ENST00000413936.2
ENST00000423646.1
ENST00000438930.1
ENST00000430490.2
DTX2
deltex homolog 2 (Drosophila)
chr15_+_90792760 0.10 ENST00000339615.5
ENST00000438251.1
TTLL13
tubulin tyrosine ligase-like family, member 13
chr20_+_44035847 0.10 ENST00000372712.2
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr12_-_49582978 0.10 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr10_+_78078088 0.10 ENST00000496424.2
C10orf11
chromosome 10 open reading frame 11
chr14_+_58894404 0.10 ENST00000554463.1
ENST00000555833.1
KIAA0586
KIAA0586
chr6_-_2751146 0.10 ENST00000268446.5
ENST00000274643.7
MYLK4
myosin light chain kinase family, member 4
chr7_-_139876734 0.09 ENST00000006967.5
JHDM1D
lysine (K)-specific demethylase 7A
chr1_+_203765437 0.09 ENST00000550078.1
ZBED6
zinc finger, BED-type containing 6
chr1_-_3566627 0.09 ENST00000419924.2
ENST00000270708.7
WRAP73
WD repeat containing, antisense to TP73
chr11_-_92930556 0.09 ENST00000529184.1
SLC36A4
solute carrier family 36 (proton/amino acid symporter), member 4
chr16_+_22518495 0.09 ENST00000541154.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr6_-_117747015 0.09 ENST00000368508.3
ENST00000368507.3
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr4_-_80994619 0.09 ENST00000404191.1
ANTXR2
anthrax toxin receptor 2
chr3_-_169487617 0.09 ENST00000330368.2
ACTRT3
actin-related protein T3
chr17_+_26662730 0.09 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr9_-_20382446 0.09 ENST00000380321.1
MLLT3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr14_+_102276192 0.09 ENST00000557714.1
PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr14_+_100070869 0.09 ENST00000502101.2
RP11-543C4.1
RP11-543C4.1
chr17_-_65235916 0.09 ENST00000579861.1
HELZ
helicase with zinc finger
chr11_-_7904464 0.09 ENST00000502624.2
ENST00000527565.1
RP11-35J10.5
RP11-35J10.5
chr7_+_6617039 0.09 ENST00000405731.3
ENST00000396713.2
ENST00000396707.2
ENST00000335965.6
ENST00000396709.1
ENST00000483589.1
ENST00000396706.2
ZDHHC4
zinc finger, DHHC-type containing 4
chr16_-_28857677 0.09 ENST00000313511.3
TUFM
Tu translation elongation factor, mitochondrial
chr1_-_114429997 0.08 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr8_+_21777159 0.08 ENST00000434536.1
ENST00000252512.9
XPO7
exportin 7
chr19_+_3880581 0.08 ENST00000450849.2
ENST00000301260.6
ENST00000398448.3
ATCAY
ataxia, cerebellar, Cayman type
chr9_-_86432547 0.08 ENST00000376365.3
ENST00000376371.2
GKAP1
G kinase anchoring protein 1
chr9_+_112852477 0.08 ENST00000480388.1
AKAP2
A kinase (PRKA) anchor protein 2
chr8_+_75512010 0.08 ENST00000518190.1
ENST00000523118.1
RP11-758M4.1
Uncharacterized protein
chr19_+_12721760 0.08 ENST00000600752.1
ENST00000540038.1
ZNF791
zinc finger protein 791
chr17_+_41363854 0.08 ENST00000588693.1
ENST00000588659.1
ENST00000541594.1
ENST00000536052.1
ENST00000331615.3
TMEM106A
transmembrane protein 106A
chr21_-_16374688 0.08 ENST00000411932.1
NRIP1
nuclear receptor interacting protein 1
chr5_-_13944652 0.08 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr11_-_102651343 0.08 ENST00000279441.4
ENST00000539681.1
MMP10
matrix metallopeptidase 10 (stromelysin 2)
chr1_-_207095212 0.08 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr6_+_12958137 0.08 ENST00000457702.2
ENST00000379345.2
PHACTR1
phosphatase and actin regulator 1
chr8_-_101321584 0.08 ENST00000523167.1
RNF19A
ring finger protein 19A, RBR E3 ubiquitin protein ligase
chr17_-_30228678 0.08 ENST00000261708.4
UTP6
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr10_-_69597828 0.08 ENST00000339758.7
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr17_+_7942424 0.08 ENST00000573359.1
ALOX15B
arachidonate 15-lipoxygenase, type B
chr19_+_35899569 0.08 ENST00000600405.1
AC002511.1
AC002511.1
chr11_+_34643600 0.08 ENST00000530286.1
ENST00000533754.1
EHF
ets homologous factor
chr17_-_71223839 0.07 ENST00000579872.1
ENST00000580032.1
FAM104A
family with sequence similarity 104, member A
chr7_-_16840820 0.07 ENST00000450569.1
AGR2
anterior gradient 2
chr9_-_136933615 0.07 ENST00000371834.2
BRD3
bromodomain containing 3
chr12_+_120740119 0.07 ENST00000536460.1
ENST00000202967.4
SIRT4
sirtuin 4
chr16_+_22516172 0.07 ENST00000543407.1
NPIPB5
nuclear pore complex interacting protein family, member B5
chr17_+_685513 0.07 ENST00000304478.4
RNMTL1
RNA methyltransferase like 1
chr10_+_124739911 0.07 ENST00000405485.1
PSTK
phosphoseryl-tRNA kinase
chr5_-_96209315 0.07 ENST00000504056.1
CTD-2260A17.2
Uncharacterized protein
chr22_-_22295029 0.07 ENST00000445205.1
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr4_+_28437071 0.07 ENST00000509416.1
RP11-123O22.1
RP11-123O22.1
chr21_+_34602377 0.07 ENST00000342101.3
ENST00000413881.1
ENST00000443073.1
IFNAR2
interferon (alpha, beta and omega) receptor 2
chr12_-_76879852 0.07 ENST00000548341.1
OSBPL8
oxysterol binding protein-like 8
chr3_+_142315294 0.07 ENST00000464320.1
PLS1
plastin 1
chr2_+_171640291 0.07 ENST00000409885.1
ERICH2
glutamate-rich 2
chr17_-_72772425 0.07 ENST00000578822.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr21_-_46293644 0.07 ENST00000330938.3
PTTG1IP
pituitary tumor-transforming 1 interacting protein
chr5_+_147774275 0.07 ENST00000513826.1
FBXO38
F-box protein 38
chr5_+_137673945 0.07 ENST00000513056.1
ENST00000511276.1
FAM53C
family with sequence similarity 53, member C
chr16_-_279405 0.07 ENST00000430864.1
ENST00000293872.8
ENST00000337351.4
ENST00000397783.1
LUC7L
LUC7-like (S. cerevisiae)
chr2_+_149402989 0.07 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr6_-_88032795 0.07 ENST00000296882.3
GJB7
gap junction protein, beta 7, 25kDa
chr17_-_6915646 0.07 ENST00000574377.1
ENST00000399541.2
ENST00000399540.2
ENST00000575727.1
ENST00000573939.1
AC027763.2
Uncharacterized protein
chrX_-_65259914 0.07 ENST00000374737.4
ENST00000455586.2
VSIG4
V-set and immunoglobulin domain containing 4
chr3_+_172468749 0.07 ENST00000366254.2
ENST00000415665.1
ENST00000438041.1
ECT2
epithelial cell transforming sequence 2 oncogene
chr14_+_102606181 0.07 ENST00000335263.5
ENST00000322340.5
ENST00000424963.2
ENST00000342702.3
ENST00000556807.1
ENST00000499851.2
ENST00000558567.1
ENST00000299135.6
ENST00000454394.2
ENST00000556511.2
WDR20
WD repeat domain 20
chr17_-_72772462 0.07 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr3_+_109128961 0.07 ENST00000489670.1
RP11-702L6.4
RP11-702L6.4
chr12_+_2986359 0.07 ENST00000538636.1
ENST00000461997.2
ENST00000489288.2
ENST00000366285.2
ENST00000538700.1
RHNO1
RAD9-HUS1-RAD1 interacting nuclear orphan 1
chr8_+_86999516 0.06 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr1_+_45140360 0.06 ENST00000418644.1
ENST00000458657.2
ENST00000441519.1
ENST00000535358.1
ENST00000445071.1
C1orf228
chromosome 1 open reading frame 228
chr14_+_97263641 0.06 ENST00000216639.3
VRK1
vaccinia related kinase 1
chr8_+_103991013 0.06 ENST00000517983.1
KB-1507C5.4
KB-1507C5.4
chr2_+_191513959 0.06 ENST00000337386.5
ENST00000357215.5
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr12_+_97306295 0.06 ENST00000457368.2
NEDD1
neural precursor cell expressed, developmentally down-regulated 1
chr9_-_35812140 0.06 ENST00000497810.1
ENST00000396638.2
ENST00000484764.1
SPAG8
sperm associated antigen 8
chr17_+_77030267 0.06 ENST00000581774.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr19_-_42931567 0.06 ENST00000244289.4
LIPE
lipase, hormone-sensitive
chr17_+_26662597 0.06 ENST00000544907.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr4_-_21950356 0.06 ENST00000447367.2
ENST00000382152.2
KCNIP4
Kv channel interacting protein 4
chr19_+_6464243 0.06 ENST00000600229.1
ENST00000356762.3
CRB3
crumbs homolog 3 (Drosophila)
chr10_+_97759848 0.06 ENST00000424464.1
ENST00000410012.2
ENST00000344386.3
CC2D2B
coiled-coil and C2 domain containing 2B
chr19_-_4831701 0.06 ENST00000248244.5
TICAM1
toll-like receptor adaptor molecule 1
chr5_+_176853669 0.06 ENST00000355472.5
GRK6
G protein-coupled receptor kinase 6
chr8_+_11666649 0.06 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr8_-_33424636 0.06 ENST00000256257.1
RNF122
ring finger protein 122
chr19_+_36486078 0.06 ENST00000378887.2
SDHAF1
succinate dehydrogenase complex assembly factor 1
chr14_-_74551172 0.06 ENST00000553458.1
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr5_-_98262240 0.06 ENST00000284049.3
CHD1
chromodomain helicase DNA binding protein 1
chr1_+_41448820 0.06 ENST00000372616.1
CTPS1
CTP synthase 1
chr1_+_246729815 0.06 ENST00000366511.1
CNST
consortin, connexin sorting protein
chr16_+_30064411 0.06 ENST00000338110.5
ALDOA
aldolase A, fructose-bisphosphate
chr8_+_101349823 0.06 ENST00000519566.1
KB-1991G8.1
KB-1991G8.1
chr15_+_35270552 0.06 ENST00000391457.2
AC114546.1
HCG37415; PRO1914; Uncharacterized protein
chr1_+_163039143 0.06 ENST00000531057.1
ENST00000527809.1
ENST00000367908.4
RGS4
regulator of G-protein signaling 4
chr16_+_30064444 0.06 ENST00000395248.1
ENST00000566897.1
ENST00000568435.1
ALDOA
aldolase A, fructose-bisphosphate
chr3_-_156272872 0.06 ENST00000476217.1
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr4_+_86748898 0.06 ENST00000509300.1
ARHGAP24
Rho GTPase activating protein 24
chr16_+_84801852 0.06 ENST00000569925.1
ENST00000567526.1
USP10
ubiquitin specific peptidase 10
chr8_+_67344710 0.06 ENST00000379385.4
ENST00000396623.3
ENST00000415254.1
ADHFE1
alcohol dehydrogenase, iron containing, 1
chr7_+_90338547 0.06 ENST00000446790.1
CDK14
cyclin-dependent kinase 14
chr6_+_26251835 0.06 ENST00000356350.2
HIST1H2BH
histone cluster 1, H2bh
chr6_-_131211534 0.06 ENST00000456097.2
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr14_-_60632162 0.06 ENST00000557185.1
DHRS7
dehydrogenase/reductase (SDR family) member 7
chr19_+_18111927 0.06 ENST00000379656.3
ARRDC2
arrestin domain containing 2
chr4_-_80994471 0.06 ENST00000295465.4
ANTXR2
anthrax toxin receptor 2
chr19_+_15160130 0.06 ENST00000427043.3
CASP14
caspase 14, apoptosis-related cysteine peptidase
chr3_-_187455680 0.06 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr11_-_61647935 0.06 ENST00000531956.1
FADS3
fatty acid desaturase 3
chr21_+_34602200 0.06 ENST00000382264.3
ENST00000382241.3
ENST00000404220.3
ENST00000342136.4
IFNAR2
interferon (alpha, beta and omega) receptor 2
chr5_+_179135246 0.06 ENST00000508787.1
CANX
calnexin
chr10_+_90521163 0.05 ENST00000404459.1
LIPN
lipase, family member N
chr1_+_241695670 0.05 ENST00000366557.4
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr7_+_74191613 0.05 ENST00000442021.2
NCF1
neutrophil cytosolic factor 1
chr19_+_43325937 0.05 ENST00000425668.1
AC004603.4
AC004603.4
chr5_-_88119580 0.05 ENST00000539796.1
MEF2C
myocyte enhancer factor 2C
chr7_+_26332645 0.05 ENST00000396376.1
SNX10
sorting nexin 10
chr8_-_93978309 0.05 ENST00000517858.1
ENST00000378861.5
TRIQK
triple QxxK/R motif containing
chr15_-_43559055 0.05 ENST00000220420.5
ENST00000349114.4
TGM5
transglutaminase 5
chr10_-_101825151 0.05 ENST00000441382.1
CPN1
carboxypeptidase N, polypeptide 1
chr2_-_240230890 0.05 ENST00000446876.1
HDAC4
histone deacetylase 4
chr14_-_58893832 0.05 ENST00000556007.2
TIMM9
translocase of inner mitochondrial membrane 9 homolog (yeast)
chr15_+_84906338 0.05 ENST00000512109.1
GOLGA6L4
golgin A6 family-like 4
chr12_-_75905374 0.05 ENST00000438169.2
ENST00000229214.4
KRR1
KRR1, small subunit (SSU) processome component, homolog (yeast)
chr9_-_35812236 0.05 ENST00000340291.2
SPAG8
sperm associated antigen 8
chr22_-_22337154 0.05 ENST00000413067.2
ENST00000437929.1
ENST00000456075.1
ENST00000434517.1
ENST00000424393.1
ENST00000449704.1
ENST00000437103.1
TOP3B
topoisomerase (DNA) III beta

Network of associatons between targets according to the STRING database.

First level regulatory network of FOXA2_FOXJ3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0045208 MAPK phosphatase export from nucleus(GO:0045208) MAPK phosphatase export from nucleus, leptomycin B sensitive(GO:0045209)
0.1 0.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.3 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.2 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0045081 negative regulation of interleukin-10 biosynthetic process(GO:0045081)
0.0 0.1 GO:0072616 interleukin-18 secretion(GO:0072616)
0.0 0.5 GO:0090292 nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.2 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.1 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:1903217 regulation of protein processing involved in protein targeting to mitochondrion(GO:1903216) negative regulation of protein processing involved in protein targeting to mitochondrion(GO:1903217)
0.0 0.2 GO:1901475 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0072308 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.3 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.1 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0 0.1 GO:0097032 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.1 GO:0015993 molecular hydrogen transport(GO:0015993)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0039008 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.0 GO:0051685 maintenance of ER location(GO:0051685)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.0 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.1 GO:0060480 lung goblet cell differentiation(GO:0060480) lobar bronchus epithelium development(GO:0060481)
0.0 0.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.1 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.0 0.0 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.1 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.3 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.3 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232) other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.1 GO:0035354 Toll-like receptor 1-Toll-like receptor 2 protein complex(GO:0035354)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.5 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.0 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1904854 proteasome core complex binding(GO:1904854)
0.1 0.2 GO:0015235 cobalamin transporter activity(GO:0015235)
0.1 0.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.3 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.1 GO:0016165 linoleate 13S-lipoxygenase activity(GO:0016165)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004905 type I interferon receptor activity(GO:0004905)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.1 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0051996 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.0 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.5 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0047946 glutamine N-acyltransferase activity(GO:0047946)
0.0 0.1 GO:0004982 N-formyl peptide receptor activity(GO:0004982)
0.0 0.0 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.1 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.0 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.1 REACTOME OPSINS Genes involved in Opsins