Project
NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
Navigation
Downloads
Results for FOSL2_SMARCC1
Z-value: 1.04
Motif logo
Transcription factors associated with FOSL2_SMARCC1
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSG00000075426.7 | FOS like 2, AP-1 transcription factor subunit | |
| ENSG00000173473.6 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1 |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| FOSL2 | hg19_v2_chr2_+_28615669_28615733 | 0.78 | 6.6e-02 | Click! |
| SMARCC1 | hg19_v2_chr3_-_47823298_47823423 | 0.21 | 6.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr14_+_38065052 Show fit | 0.92 |
ENST00000556845.1
|
tetratricopeptide repeat domain 6 |
|
| chr11_+_393428 Show fit | 0.91 |
ENST00000533249.1
ENST00000527442.1 |
plakophilin 3 |
|
| chr19_+_39279838 Show fit | 0.86 |
ENST00000314980.4
|
lectin, galactoside-binding, soluble, 7B |
|
| chr3_+_69134124 Show fit | 0.86 |
ENST00000478935.1
|
ADP-ribosylation-like factor 6 interacting protein 5 |
|
| chr1_+_156084461 Show fit | 0.79 |
ENST00000347559.2
ENST00000361308.4 ENST00000368300.4 ENST00000368299.3 |
lamin A/C |
|
| chr11_+_394145 Show fit | 0.78 |
ENST00000528036.1
|
plakophilin 3 |
|
| chr3_-_48601206 Show fit | 0.76 |
ENST00000273610.3
|
urocortin 2 |
|
| chr5_-_176923803 Show fit | 0.75 |
ENST00000506161.1
|
PDZ and LIM domain 7 (enigma) |
|
| chr7_-_35013217 Show fit | 0.70 |
ENST00000446375.1
|
dpy-19-like 1 (C. elegans) |
|
| chr19_-_19739321 Show fit | 0.69 |
ENST00000588461.1
|
lysophosphatidic acid receptor 2 |
Network of associatons between targets according to the STRING database.
First level regulatory network of FOSL2_SMARCC1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.1 | GO:0002159 | desmosome assembly(GO:0002159) |
| 0.4 | 1.8 | GO:0035105 | sterol regulatory element binding protein import into nucleus(GO:0035105) |
| 0.1 | 0.8 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.1 | 0.8 | GO:0002036 | regulation of L-glutamate transport(GO:0002036) |
| 0.1 | 0.7 | GO:0018406 | protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406) |
| 0.0 | 0.7 | GO:0038203 | TORC2 signaling(GO:0038203) |
| 0.0 | 0.7 | GO:0009950 | dorsal/ventral axis specification(GO:0009950) |
| 0.0 | 0.7 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.2 | 0.6 | GO:0006117 | acetaldehyde metabolic process(GO:0006117) |
| 0.1 | 0.6 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 1.8 | GO:0005638 | lamin filament(GO:0005638) |
| 0.1 | 1.8 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
| 0.0 | 1.7 | GO:0097517 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
| 0.0 | 0.7 | GO:0031932 | TORC2 complex(GO:0031932) |
| 0.2 | 0.6 | GO:0035525 | NF-kappaB p50/p65 complex(GO:0035525) |
| 0.1 | 0.6 | GO:0033263 | CORVET complex(GO:0033263) |
| 0.0 | 0.6 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.0 | 0.6 | GO:0043034 | costamere(GO:0043034) |
| 0.1 | 0.5 | GO:0070110 | ciliary neurotrophic factor receptor complex(GO:0070110) |
| 0.0 | 0.4 | GO:0042627 | chylomicron(GO:0042627) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.1 | GO:0045294 | alpha-catenin binding(GO:0045294) |
| 0.0 | 1.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.2 | 0.9 | GO:1990175 | EH domain binding(GO:1990175) |
| 0.1 | 0.8 | GO:0051429 | corticotropin-releasing hormone receptor binding(GO:0051429) |
| 0.1 | 0.7 | GO:0070915 | lysophosphatidic acid receptor activity(GO:0070915) |
| 0.0 | 0.7 | GO:0000030 | mannosyltransferase activity(GO:0000030) |
| 0.0 | 0.7 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.2 | 0.6 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
| 0.1 | 0.6 | GO:0008665 | 2'-phosphotransferase activity(GO:0008665) |
| 0.0 | 0.6 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.8 | PID RET PATHWAY | Signaling events regulated by Ret tyrosine kinase |
| 0.0 | 1.5 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.0 | 0.8 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.6 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.0 | 0.6 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
| 0.0 | 0.4 | SA MMP CYTOKINE CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
| 0.0 | 0.3 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 0.2 | SA TRKA RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.0 | 0.2 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 0.0 | PID IL8 CXCR1 PATHWAY | IL8- and CXCR1-mediated signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 2.1 | REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS | Genes involved in Apoptotic cleavage of cellular proteins |
| 0.0 | 0.6 | REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL | Genes involved in NF-kB is activated and signals survival |
| 0.0 | 0.5 | REACTOME ETHANOL OXIDATION | Genes involved in Ethanol oxidation |
| 0.0 | 0.5 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 0.4 | REACTOME ACTIVATION OF RAC | Genes involved in Activation of Rac |
| 0.0 | 0.4 | REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL | Genes involved in AKT phosphorylates targets in the cytosol |
| 0.0 | 0.3 | REACTOME PURINE CATABOLISM | Genes involved in Purine catabolism |
| 0.0 | 0.3 | REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS | Genes involved in ABCA transporters in lipid homeostasis |
| 0.0 | 0.3 | REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS | Genes involved in p130Cas linkage to MAPK signaling for integrins |
| 0.0 | 0.2 | REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |