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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for FOSL2_SMARCC1

Z-value: 1.04

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Transcription factors associated with FOSL2_SMARCC1

Gene Symbol Gene ID Gene Info
FOSL2
ENSG00000075426.7 FOS like 2, AP-1 transcription factor subunit
SMARCC1
ENSG00000173473.6 SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSL2hg19_v2_chr2_+_28615669_286157330.786.6e-02Click!
SMARCC1hg19_v2_chr3_-_47823298_478234230.216.8e-01Click!

Activity profile of FOSL2_SMARCC1 motif

Sorted Z-values of FOSL2_SMARCC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr14_+_38065052 0.92 ENST00000556845.1
TTC6
tetratricopeptide repeat domain 6
chr11_+_393428 0.91 ENST00000533249.1
ENST00000527442.1
PKP3
plakophilin 3
chr19_+_39279838 0.86 ENST00000314980.4
LGALS7B
lectin, galactoside-binding, soluble, 7B
chr3_+_69134124 0.86 ENST00000478935.1
ARL6IP5
ADP-ribosylation-like factor 6 interacting protein 5
chr1_+_156084461 0.79 ENST00000347559.2
ENST00000361308.4
ENST00000368300.4
ENST00000368299.3
LMNA
lamin A/C
chr11_+_394145 0.78 ENST00000528036.1
PKP3
plakophilin 3
chr3_-_48601206 0.76 ENST00000273610.3
UCN2
urocortin 2
chr5_-_176923803 0.75 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr7_-_35013217 0.70 ENST00000446375.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr19_-_19739321 0.69 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr3_+_184534994 0.60 ENST00000441141.1
ENST00000445089.1
VPS8
vacuolar protein sorting 8 homolog (S. cerevisiae)
chr1_+_156096336 0.60 ENST00000504687.1
ENST00000473598.2
LMNA
lamin A/C
chr17_+_48611853 0.59 ENST00000507709.1
ENST00000515126.1
ENST00000507467.1
EPN3
epsin 3
chr7_-_33080506 0.56 ENST00000381626.2
ENST00000409467.1
ENST00000449201.1
NT5C3A
5'-nucleotidase, cytosolic IIIA
chr4_+_11627248 0.54 ENST00000510095.1
RP11-281P23.2
RP11-281P23.2
chr11_-_62323702 0.52 ENST00000530285.1
AHNAK
AHNAK nucleoprotein
chr10_-_98347063 0.51 ENST00000443638.1
TM9SF3
transmembrane 9 superfamily member 3
chr2_+_89952792 0.51 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr3_+_48507210 0.50 ENST00000433541.1
ENST00000422277.2
ENST00000436480.2
ENST00000444177.1
TREX1
three prime repair exonuclease 1
chr12_-_10282742 0.49 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr16_-_4664860 0.48 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBALD1
UBA-like domain containing 1
chr14_+_64970427 0.48 ENST00000553583.1
ZBTB1
zinc finger and BTB domain containing 1
chr3_-_12200851 0.47 ENST00000287814.4
TIMP4
TIMP metallopeptidase inhibitor 4
chr11_-_2950642 0.46 ENST00000314222.4
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr16_-_4665023 0.45 ENST00000591897.1
UBALD1
UBA-like domain containing 1
chr1_+_156095951 0.45 ENST00000448611.2
ENST00000368297.1
LMNA
lamin A/C
chr6_+_41604620 0.44 ENST00000432027.1
MDFI
MyoD family inhibitor
chr12_-_78934441 0.42 ENST00000546865.1
ENST00000547089.1
RP11-171L9.1
RP11-171L9.1
chr14_+_77425972 0.42 ENST00000553613.1
RP11-7F17.7
RP11-7F17.7
chr16_+_28505955 0.41 ENST00000564831.1
ENST00000328423.5
ENST00000431282.1
APOBR
apolipoprotein B receptor
chr11_-_66103932 0.41 ENST00000311320.4
RIN1
Ras and Rab interactor 1
chr7_+_151791095 0.40 ENST00000422997.2
GALNT11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11 (GalNAc-T11)
chr1_-_153521714 0.39 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr9_+_140119618 0.38 ENST00000359069.2
C9orf169
chromosome 9 open reading frame 169
chr8_-_71157595 0.38 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chr9_+_92219919 0.38 ENST00000252506.6
ENST00000375769.1
GADD45G
growth arrest and DNA-damage-inducible, gamma
chr5_-_176923846 0.36 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr11_+_394196 0.35 ENST00000331563.2
ENST00000531857.1
PKP3
plakophilin 3
chr10_+_86088337 0.35 ENST00000359979.4
CCSER2
coiled-coil serine-rich protein 2
chr11_+_36397915 0.34 ENST00000526682.1
ENST00000530252.1
PRR5L
proline rich 5 like
chr17_+_7123207 0.34 ENST00000584103.1
ENST00000579886.2
ACADVL
acyl-CoA dehydrogenase, very long chain
chr12_+_64798095 0.34 ENST00000332707.5
XPOT
exportin, tRNA
chr3_-_48632593 0.33 ENST00000454817.1
ENST00000328333.8
COL7A1
collagen, type VII, alpha 1
chr2_-_96926313 0.33 ENST00000435268.1
TMEM127
transmembrane protein 127
chr11_-_65429891 0.33 ENST00000527874.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr15_+_89182156 0.33 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr19_-_44008863 0.33 ENST00000601646.1
PHLDB3
pleckstrin homology-like domain, family B, member 3
chr11_-_119066545 0.32 ENST00000415318.1
CCDC153
coiled-coil domain containing 153
chr1_+_27669719 0.32 ENST00000473280.1
SYTL1
synaptotagmin-like 1
chr1_-_153935791 0.32 ENST00000429040.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr19_-_36019123 0.32 ENST00000588674.1
ENST00000452271.2
ENST00000518157.1
SBSN
suprabasin
chr6_+_63921351 0.31 ENST00000370659.1
FKBP1C
FK506 binding protein 1C
chr11_+_28724129 0.31 ENST00000513853.1
RP11-115J23.1
RP11-115J23.1
chr7_-_150721570 0.30 ENST00000377974.2
ENST00000444312.1
ENST00000605938.1
ENST00000605952.1
ATG9B
autophagy related 9B
chr1_+_161692449 0.30 ENST00000367946.3
ENST00000367945.1
ENST00000336830.5
ENST00000367944.3
ENST00000392158.1
FCRLB
Fc receptor-like B
chrX_-_129244336 0.29 ENST00000434609.1
ELF4
E74-like factor 4 (ets domain transcription factor)
chr6_+_41604747 0.28 ENST00000419164.1
ENST00000373051.2
MDFI
MyoD family inhibitor
chr17_-_48133054 0.28 ENST00000499842.1
RP11-1094H24.4
RP11-1094H24.4
chr19_+_7953417 0.28 ENST00000600345.1
ENST00000598224.1
LRRC8E
leucine rich repeat containing 8 family, member E
chr6_-_4347271 0.28 ENST00000437430.2
RP3-527G5.1
RP3-527G5.1
chr3_-_49395705 0.27 ENST00000419349.1
GPX1
glutathione peroxidase 1
chr1_+_154377669 0.27 ENST00000368485.3
ENST00000344086.4
IL6R
interleukin 6 receptor
chr1_-_8000872 0.27 ENST00000377507.3
TNFRSF9
tumor necrosis factor receptor superfamily, member 9
chr1_-_153935738 0.27 ENST00000417348.1
SLC39A1
solute carrier family 39 (zinc transporter), member 1
chr1_+_154378049 0.27 ENST00000512471.1
IL6R
interleukin 6 receptor
chr17_+_75315654 0.26 ENST00000590595.1
SEPT9
septin 9
chr16_+_83986827 0.26 ENST00000393306.1
ENST00000565123.1
OSGIN1
oxidative stress induced growth inhibitor 1
chr8_-_123139423 0.26 ENST00000523792.1
RP11-398G24.2
RP11-398G24.2
chr3_+_124223586 0.26 ENST00000393496.1
KALRN
kalirin, RhoGEF kinase
chr7_+_134528635 0.26 ENST00000445569.2
CALD1
caldesmon 1
chr11_-_94965667 0.26 ENST00000542176.1
ENST00000278499.2
SESN3
sestrin 3
chr17_-_29641104 0.25 ENST00000577894.1
ENST00000330927.4
EVI2B
ecotropic viral integration site 2B
chr19_-_51538148 0.25 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chr16_+_30077098 0.25 ENST00000395240.3
ENST00000566846.1
ALDOA
aldolase A, fructose-bisphosphate
chr17_-_70417365 0.25 ENST00000580948.1
LINC00511
long intergenic non-protein coding RNA 511
chr5_-_141030943 0.25 ENST00000522783.1
ENST00000519800.1
ENST00000435817.2
FCHSD1
FCH and double SH3 domains 1
chr17_-_8263538 0.25 ENST00000535173.1
AC135178.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr3_+_19988736 0.25 ENST00000443878.1
RAB5A
RAB5A, member RAS oncogene family
chr11_+_1855645 0.25 ENST00000381968.3
ENST00000381978.3
SYT8
synaptotagmin VIII
chr21_-_36421535 0.25 ENST00000416754.1
ENST00000437180.1
ENST00000455571.1
RUNX1
runt-related transcription factor 1
chr16_+_1832902 0.24 ENST00000262302.9
ENST00000563136.1
ENST00000565987.1
ENST00000543305.1
ENST00000568287.1
ENST00000565134.1
NUBP2
nucleotide binding protein 2
chr4_-_100356291 0.24 ENST00000476959.1
ENST00000482593.1
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr5_+_149877440 0.24 ENST00000518299.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr19_-_51523412 0.24 ENST00000391805.1
ENST00000599077.1
KLK10
kallikrein-related peptidase 10
chr19_-_46285646 0.24 ENST00000458663.2
DMPK
dystrophia myotonica-protein kinase
chr1_-_153113927 0.24 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr11_-_66103867 0.24 ENST00000424433.2
RIN1
Ras and Rab interactor 1
chr11_-_65430251 0.24 ENST00000534283.1
ENST00000527749.1
ENST00000533187.1
ENST00000525693.1
ENST00000534558.1
ENST00000532879.1
ENST00000532999.1
RELA
v-rel avian reticuloendotheliosis viral oncogene homolog A
chr7_+_73245193 0.23 ENST00000340958.2
CLDN4
claudin 4
chr2_+_90192768 0.23 ENST00000390275.2
IGKV1D-13
immunoglobulin kappa variable 1D-13
chr16_-_122619 0.23 ENST00000262316.6
RHBDF1
rhomboid 5 homolog 1 (Drosophila)
chr1_+_6511651 0.23 ENST00000434576.1
ESPN
espin
chr8_+_55467072 0.23 ENST00000602362.1
RP11-53M11.3
RP11-53M11.3
chr16_-_75301886 0.23 ENST00000393422.2
BCAR1
breast cancer anti-estrogen resistance 1
chr2_-_238499337 0.23 ENST00000411462.1
ENST00000409822.1
RAB17
RAB17, member RAS oncogene family
chr4_+_108746282 0.23 ENST00000503862.1
SGMS2
sphingomyelin synthase 2
chr15_+_41245160 0.23 ENST00000444189.2
ENST00000446533.3
CHAC1
ChaC, cation transport regulator homolog 1 (E. coli)
chr8_+_120220561 0.22 ENST00000276681.6
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr3_+_14474178 0.22 ENST00000452775.1
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr8_+_124780672 0.22 ENST00000521166.1
ENST00000334705.7
FAM91A1
family with sequence similarity 91, member A1
chr3_-_45957088 0.22 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr7_-_135433534 0.21 ENST00000338588.3
FAM180A
family with sequence similarity 180, member A
chr15_-_74504560 0.21 ENST00000449139.2
STRA6
stimulated by retinoic acid 6
chr18_+_61254570 0.21 ENST00000344731.5
SERPINB13
serpin peptidase inhibitor, clade B (ovalbumin), member 13
chr8_-_141774467 0.21 ENST00000520151.1
ENST00000519024.1
ENST00000519465.1
PTK2
protein tyrosine kinase 2
chr20_-_17539456 0.21 ENST00000544874.1
ENST00000377868.2
BFSP1
beaded filament structural protein 1, filensin
chr5_+_76012009 0.21 ENST00000505600.1
F2R
coagulation factor II (thrombin) receptor
chr4_-_100356551 0.21 ENST00000209665.4
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr2_-_220173685 0.21 ENST00000423636.2
ENST00000442029.1
ENST00000412847.1
PTPRN
protein tyrosine phosphatase, receptor type, N
chr17_-_55162360 0.21 ENST00000576871.1
ENST00000576313.1
RP11-166P13.3
RP11-166P13.3
chr21_-_36421626 0.21 ENST00000300305.3
RUNX1
runt-related transcription factor 1
chr21_+_30672433 0.20 ENST00000451655.1
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr1_-_223853425 0.20 ENST00000366873.2
ENST00000419193.2
CAPN8
calpain 8
chr3_+_57094469 0.20 ENST00000334325.1
SPATA12
spermatogenesis associated 12
chr17_-_25568687 0.20 ENST00000581944.1
RP11-663N22.1
RP11-663N22.1
chr11_-_2924720 0.20 ENST00000455942.2
SLC22A18AS
solute carrier family 22 (organic cation transporter), member 18 antisense
chr11_+_844067 0.20 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
TSPAN4
tetraspanin 4
chr6_-_119031228 0.20 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr16_+_30077055 0.20 ENST00000564595.2
ENST00000569798.1
ALDOA
aldolase A, fructose-bisphosphate
chr4_-_39034542 0.20 ENST00000344606.6
TMEM156
transmembrane protein 156
chr10_+_102672712 0.19 ENST00000370271.3
ENST00000370269.3
ENST00000609386.1
FAM178A
family with sequence similarity 178, member A
chr1_-_244006528 0.19 ENST00000336199.5
ENST00000263826.5
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr10_-_98346801 0.19 ENST00000371142.4
TM9SF3
transmembrane 9 superfamily member 3
chr18_+_52495426 0.19 ENST00000262094.5
RAB27B
RAB27B, member RAS oncogene family
chr1_+_40627038 0.19 ENST00000372771.4
RLF
rearranged L-myc fusion
chr1_+_36621697 0.19 ENST00000373150.4
ENST00000373151.2
MAP7D1
MAP7 domain containing 1
chr18_+_48918368 0.19 ENST00000583982.1
ENST00000578152.1
ENST00000583609.1
ENST00000435144.1
ENST00000580841.1
RP11-267C16.1
RP11-267C16.1
chr11_+_844406 0.19 ENST00000397404.1
TSPAN4
tetraspanin 4
chr1_+_36621529 0.19 ENST00000316156.4
MAP7D1
MAP7 domain containing 1
chr11_-_47207390 0.19 ENST00000539589.1
ENST00000528462.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr17_+_21191341 0.19 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3
mitogen-activated protein kinase kinase 3
chr16_+_30968615 0.19 ENST00000262519.8
SETD1A
SET domain containing 1A
chr11_-_111794446 0.18 ENST00000527950.1
CRYAB
crystallin, alpha B
chr1_-_21059029 0.18 ENST00000444387.2
ENST00000375031.1
ENST00000518294.1
SH2D5
SH2 domain containing 5
chr11_-_118134997 0.18 ENST00000278937.2
MPZL2
myelin protein zero-like 2
chr16_+_57662419 0.18 ENST00000388812.4
ENST00000538815.1
ENST00000456916.1
ENST00000567154.1
ENST00000388813.5
ENST00000562558.1
ENST00000566271.2
GPR56
G protein-coupled receptor 56
chr17_-_38721711 0.18 ENST00000578085.1
ENST00000246657.2
CCR7
chemokine (C-C motif) receptor 7
chr17_-_29641084 0.18 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr15_+_89182178 0.18 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr7_+_143078379 0.18 ENST00000449630.1
ENST00000457235.1
ZYX
zyxin
chr8_+_22446763 0.18 ENST00000450780.2
ENST00000430850.2
ENST00000447849.1
AC037459.4
Uncharacterized protein
chr3_+_178865887 0.18 ENST00000477735.1
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr2_+_220495800 0.18 ENST00000413743.1
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr17_+_73780852 0.18 ENST00000589666.1
UNK
unkempt family zinc finger
chr9_-_139922726 0.17 ENST00000265662.5
ENST00000371605.3
ABCA2
ATP-binding cassette, sub-family A (ABC1), member 2
chr19_-_46285736 0.17 ENST00000291270.4
ENST00000447742.2
ENST00000354227.5
DMPK
dystrophia myotonica-protein kinase
chr12_-_48152611 0.17 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr17_+_48610074 0.17 ENST00000503690.1
ENST00000514874.1
ENST00000537145.1
ENST00000541226.1
EPN3
epsin 3
chr15_+_40532058 0.17 ENST00000260404.4
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr1_+_15256230 0.17 ENST00000376028.4
ENST00000400798.2
KAZN
kazrin, periplakin interacting protein
chr11_+_10326612 0.17 ENST00000534464.1
ENST00000530439.1
ENST00000524948.1
ENST00000528655.1
ENST00000526492.1
ENST00000525063.1
ADM
adrenomedullin
chr5_-_134914673 0.17 ENST00000512158.1
CXCL14
chemokine (C-X-C motif) ligand 14
chr16_-_74330612 0.17 ENST00000569389.1
ENST00000562888.1
AC009120.4
AC009120.4
chr15_-_44828838 0.17 ENST00000560750.1
EIF3J-AS1
EIF3J antisense RNA 1 (head to head)
chrX_+_15767971 0.17 ENST00000479740.1
ENST00000454127.2
CA5B
carbonic anhydrase VB, mitochondrial
chr16_+_30675654 0.17 ENST00000287468.5
ENST00000395073.2
FBRS
fibrosin
chr11_+_1856034 0.17 ENST00000341958.3
SYT8
synaptotagmin VIII
chr9_-_114246332 0.17 ENST00000602978.1
KIAA0368
KIAA0368
chr3_-_122512619 0.17 ENST00000383659.1
ENST00000306103.2
HSPBAP1
HSPB (heat shock 27kDa) associated protein 1
chr12_+_57914481 0.16 ENST00000548887.1
MBD6
methyl-CpG binding domain protein 6
chr17_+_79071365 0.16 ENST00000576756.1
BAIAP2
BAI1-associated protein 2
chr13_-_30683005 0.16 ENST00000413591.1
ENST00000432770.1
LINC00365
long intergenic non-protein coding RNA 365
chr3_-_98241598 0.16 ENST00000513287.1
ENST00000514537.1
ENST00000508071.1
ENST00000507944.1
CLDND1
claudin domain containing 1
chr10_-_31288398 0.16 ENST00000538351.2
ZNF438
zinc finger protein 438
chr5_-_138534071 0.16 ENST00000394817.2
SIL1
SIL1 nucleotide exchange factor
chr13_-_86373536 0.16 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr15_-_75748143 0.16 ENST00000568431.1
ENST00000568309.1
ENST00000568190.1
ENST00000570115.1
ENST00000564778.1
SIN3A
SIN3 transcription regulator family member A
chr15_+_44829255 0.16 ENST00000261868.5
ENST00000424492.3
EIF3J
eukaryotic translation initiation factor 3, subunit J
chr2_+_201170999 0.16 ENST00000439395.1
ENST00000444012.1
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr9_-_32573130 0.16 ENST00000350021.2
ENST00000379847.3
NDUFB6
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa
chr1_-_156675368 0.16 ENST00000368222.3
CRABP2
cellular retinoic acid binding protein 2
chr12_-_111395610 0.16 ENST00000548329.1
ENST00000546852.1
RP1-46F2.3
RP1-46F2.3
chr3_-_196065374 0.16 ENST00000454715.1
TM4SF19
transmembrane 4 L six family member 19
chrX_+_150565038 0.16 ENST00000370361.1
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr3_-_178865747 0.16 ENST00000435560.1
RP11-360P21.2
RP11-360P21.2
chr2_+_242681835 0.15 ENST00000437164.1
ENST00000454048.1
ENST00000417686.1
D2HGDH
D-2-hydroxyglutarate dehydrogenase
chr1_+_901847 0.15 ENST00000379410.3
ENST00000379409.2
ENST00000379407.3
PLEKHN1
pleckstrin homology domain containing, family N member 1
chr12_-_102591604 0.15 ENST00000329406.4
PMCH
pro-melanin-concentrating hormone
chr17_-_39769005 0.15 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr15_+_38964048 0.15 ENST00000560203.1
ENST00000557946.1
RP11-275I4.2
RP11-275I4.2
chr15_+_41136263 0.15 ENST00000568823.1
SPINT1
serine peptidase inhibitor, Kunitz type 1
chr12_-_48152853 0.15 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr8_-_145025044 0.15 ENST00000322810.4
PLEC
plectin
chr17_-_73775839 0.15 ENST00000592643.1
ENST00000591890.1
ENST00000587171.1
ENST00000254810.4
ENST00000589599.1
H3F3B
H3 histone, family 3B (H3.3B)
chr12_-_122238464 0.15 ENST00000546227.1
RHOF
ras homolog family member F (in filopodia)
chr6_+_74405804 0.15 ENST00000287097.5
CD109
CD109 molecule
chr3_-_46608010 0.15 ENST00000395905.3
LRRC2
leucine rich repeat containing 2
chr1_-_43751230 0.15 ENST00000523677.1
C1orf210
chromosome 1 open reading frame 210
chr11_-_66104237 0.15 ENST00000530056.1
RIN1
Ras and Rab interactor 1
chr11_-_82782952 0.15 ENST00000534141.1
RAB30
RAB30, member RAS oncogene family
chr8_+_125860939 0.15 ENST00000525292.1
ENST00000528090.1
LINC00964
long intergenic non-protein coding RNA 964
chr19_+_38794797 0.15 ENST00000301246.5
ENST00000588605.1
C19orf33
chromosome 19 open reading frame 33
chr16_-_31161380 0.15 ENST00000569305.1
ENST00000418068.2
ENST00000268281.4
PRSS36
protease, serine, 36
chr17_+_79650962 0.15 ENST00000329138.4
HGS
hepatocyte growth factor-regulated tyrosine kinase substrate
chr14_+_22600515 0.15 ENST00000390456.3
TRAV8-7
T cell receptor alpha variable 8-7 (non-functional)
chr18_+_1099004 0.14 ENST00000581556.1
RP11-78F17.1
RP11-78F17.1
chr6_+_151358048 0.14 ENST00000450635.1
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr3_-_45957534 0.14 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr19_+_10400615 0.14 ENST00000221980.4
ICAM5
intercellular adhesion molecule 5, telencephalin
chr2_+_47596634 0.14 ENST00000419334.1
EPCAM
epithelial cell adhesion molecule

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL2_SMARCC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.2 2.1 GO:0002159 desmosome assembly(GO:0002159)
0.2 0.6 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.2 0.5 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.5 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.1 0.4 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.4 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.4 GO:2000176 regulation of pro-T cell differentiation(GO:2000174) positive regulation of pro-T cell differentiation(GO:2000176)
0.1 0.3 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.8 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.1 0.3 GO:0099541 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.1 0.8 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.2 GO:1902173 negative regulation of keratinocyte apoptotic process(GO:1902173)
0.1 0.3 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.3 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.3 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.1 0.7 GO:0018406 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1 0.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.2 GO:1904404 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.5 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.2 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 0.5 GO:0070120 ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.1 0.2 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.2 GO:0019516 lactate oxidation(GO:0019516)
0.1 0.3 GO:0061143 alveolar primary septum development(GO:0061143)
0.0 0.1 GO:1902362 melanocyte apoptotic process(GO:1902362)
0.0 0.3 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.2 GO:0060995 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.0 0.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.3 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.3 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.4 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.6 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.7 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 0.3 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.2 GO:2000501 regulation of natural killer cell chemotaxis(GO:2000501)
0.0 0.2 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0051771 nitric oxide homeostasis(GO:0033484) negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.5 GO:0009756 carbohydrate mediated signaling(GO:0009756)
0.0 0.4 GO:0034447 very-low-density lipoprotein particle clearance(GO:0034447)
0.0 0.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.2 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) transformation of host cell by virus(GO:0019087) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.3 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0060734 regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:0060734)
0.0 0.2 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.3 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0 0.1 GO:0006218 uridine catabolic process(GO:0006218)
0.0 0.1 GO:0042727 flavin-containing compound biosynthetic process(GO:0042727)
0.0 0.7 GO:0009950 dorsal/ventral axis specification(GO:0009950)
0.0 0.1 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.3 GO:0070307 lens fiber cell development(GO:0070307)
0.0 0.2 GO:0046449 creatinine metabolic process(GO:0046449)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.1 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.0 0.1 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0070370 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.1 GO:0032904 viral protein processing(GO:0019082) regulation of nerve growth factor production(GO:0032903) negative regulation of nerve growth factor production(GO:0032904) dibasic protein processing(GO:0090472)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.2 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.6 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.0 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 0.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:0086098 cellular response to progesterone stimulus(GO:0071393) angiotensin-activated signaling pathway involved in heart process(GO:0086098)
0.0 0.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.0 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.1 GO:0035879 plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.4 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0060179 male mating behavior(GO:0060179)
0.0 0.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.0 GO:0032203 telomere formation via telomerase(GO:0032203)
0.0 0.1 GO:0070384 Harderian gland development(GO:0070384)
0.0 0.1 GO:0097070 ductus arteriosus closure(GO:0097070)
0.0 0.1 GO:1901093 regulation of protein tetramerization(GO:1901090) negative regulation of protein tetramerization(GO:1901091) regulation of protein homotetramerization(GO:1901093) negative regulation of protein homotetramerization(GO:1901094)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.0 GO:0048627 myoblast development(GO:0048627)
0.0 0.1 GO:0015819 lysine transport(GO:0015819) L-lysine transport(GO:1902022) L-lysine transmembrane transport(GO:1903401)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.1 GO:1902304 positive regulation of potassium ion export(GO:1902304)
0.0 0.1 GO:0097240 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.0 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792) regulation of determination of dorsal identity(GO:2000015)
0.0 0.1 GO:0032796 uropod organization(GO:0032796)
0.0 0.1 GO:0097211 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.0 0.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.0 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.2 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.2 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.0 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:0033132 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.2 1.8 GO:0005638 lamin filament(GO:0005638)
0.1 0.5 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.1 0.3 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.6 GO:0033263 CORVET complex(GO:0033263)
0.1 1.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.2 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.7 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.3 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.3 GO:0097413 Lewy body(GO:0097413)
0.0 0.4 GO:0042627 chylomicron(GO:0042627)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.3 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0019031 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.1 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.2 GO:0005844 polysome(GO:0005844)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.0 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.6 GO:0043034 costamere(GO:0043034)
0.0 0.0 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 1.7 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.1 GO:0030891 VCB complex(GO:0030891)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:1990175 EH domain binding(GO:1990175)
0.2 0.6 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 0.5 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.1 0.5 GO:0004031 aldehyde oxidase activity(GO:0004031)
0.1 0.6 GO:0008665 2'-phosphotransferase activity(GO:0008665)
0.1 0.3 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.5 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 2.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.4 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.8 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429)
0.1 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.4 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.2 GO:0016898 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.0 0.5 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.2 GO:0033906 protein tyrosine kinase inhibitor activity(GO:0030292) hyaluronoglucuronidase activity(GO:0033906)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0070984 SET domain binding(GO:0070984)
0.0 0.1 GO:0019976 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.2 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0004968 gonadotropin-releasing hormone receptor activity(GO:0004968)
0.0 0.1 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.1 GO:0070026 nitric oxide binding(GO:0070026)
0.0 0.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.5 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.7 GO:0000030 mannosyltransferase activity(GO:0000030)
0.0 0.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.3 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.2 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.0 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.0 0.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.4 GO:0038187 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.8 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 1.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.0 PID FAS PATHWAY FAS (CD95) signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 2.1 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins