Project

NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

Navigation
Downloads

Results for FOSL1

Z-value: 1.60

Motif logo

logo of

Transcription factors associated with FOSL1

Gene Symbol Gene ID Gene Info
FOSL1
ENSG00000175592.4 FOS like 1, AP-1 transcription factor subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
FOSL1hg19_v2_chr11_-_65667997_656680440.961.9e-03Click!

Activity profile of FOSL1 motif

Sorted Z-values of FOSL1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_153013588 3.91 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr7_+_22766766 3.54 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
IL6
interleukin 6 (interferon, beta 2)
chr1_-_153066998 2.78 ENST00000368750.3
SPRR2E
small proline-rich protein 2E
chr4_+_74606223 2.69 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr20_+_44637526 2.40 ENST00000372330.3
MMP9
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr12_-_58159361 1.97 ENST00000546567.1
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr1_-_153029980 1.90 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr6_+_138188551 1.87 ENST00000237289.4
ENST00000433680.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr6_+_138188351 1.78 ENST00000421450.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr5_+_147582348 1.76 ENST00000514389.1
SPINK6
serine peptidase inhibitor, Kazal type 6
chr3_+_14474178 1.65 ENST00000452775.1
SLC6A6
solute carrier family 6 (neurotransmitter transporter), member 6
chr6_+_138188378 1.63 ENST00000420009.1
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr1_+_152956549 1.54 ENST00000307122.2
SPRR1A
small proline-rich protein 1A
chr2_-_241835561 1.43 ENST00000388934.4
C2orf54
chromosome 2 open reading frame 54
chr17_-_42994283 1.31 ENST00000593179.1
GFAP
glial fibrillary acidic protein
chr1_+_152881014 1.31 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr19_-_6670128 1.29 ENST00000245912.3
TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr10_+_104155450 1.08 ENST00000471698.1
ENST00000189444.6
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr1_+_153003671 1.06 ENST00000307098.4
SPRR1B
small proline-rich protein 1B
chr15_+_89182178 1.06 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr12_+_56732658 1.05 ENST00000228534.4
IL23A
interleukin 23, alpha subunit p19
chr18_+_61554932 1.03 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr6_-_30685214 1.02 ENST00000425072.1
MDC1
mediator of DNA-damage checkpoint 1
chr14_-_75083313 1.00 ENST00000556652.1
ENST00000555313.1
CTD-2207P18.2
CTD-2207P18.2
chr22_-_30642728 0.97 ENST00000403987.3
LIF
leukemia inhibitory factor
chr11_+_28724129 0.93 ENST00000513853.1
RP11-115J23.1
RP11-115J23.1
chr11_-_102826434 0.92 ENST00000340273.4
ENST00000260302.3
MMP13
matrix metallopeptidase 13 (collagenase 3)
chr17_-_39769005 0.91 ENST00000301653.4
ENST00000593067.1
KRT16
keratin 16
chr11_-_102668879 0.91 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr14_-_51863853 0.90 ENST00000556762.1
RP11-255G12.3
RP11-255G12.3
chr7_+_73245193 0.90 ENST00000340958.2
CLDN4
claudin 4
chr15_+_89182156 0.88 ENST00000379224.5
ISG20
interferon stimulated exonuclease gene 20kDa
chr22_-_30642782 0.86 ENST00000249075.3
LIF
leukemia inhibitory factor
chr1_-_95007193 0.85 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr10_+_30723105 0.81 ENST00000375322.2
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr22_+_37959647 0.80 ENST00000415670.1
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr10_+_30723045 0.79 ENST00000542547.1
ENST00000415139.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr5_+_35856951 0.78 ENST00000303115.3
ENST00000343305.4
ENST00000506850.1
ENST00000511982.1
IL7R
interleukin 7 receptor
chr2_+_27505260 0.77 ENST00000380075.2
ENST00000296098.4
TRIM54
tripartite motif containing 54
chr10_+_30722866 0.75 ENST00000263056.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr6_+_106546808 0.74 ENST00000369089.3
PRDM1
PR domain containing 1, with ZNF domain
chr4_+_84457250 0.74 ENST00000395226.2
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr16_+_89988259 0.73 ENST00000554444.1
ENST00000556565.1
TUBB3
Tubulin beta-3 chain
chr11_-_65667884 0.73 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr2_+_152214098 0.72 ENST00000243347.3
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr19_-_51538148 0.71 ENST00000319590.4
ENST00000250351.4
KLK12
kallikrein-related peptidase 12
chr17_+_74261413 0.71 ENST00000587913.1
UBALD2
UBA-like domain containing 2
chr16_+_30077055 0.71 ENST00000564595.2
ENST00000569798.1
ALDOA
aldolase A, fructose-bisphosphate
chr12_+_48152774 0.70 ENST00000549243.1
SLC48A1
solute carrier family 48 (heme transporter), member 1
chr11_-_65667997 0.69 ENST00000312562.2
ENST00000534222.1
FOSL1
FOS-like antigen 1
chr16_+_30751953 0.68 ENST00000483578.1
RP11-2C24.4
RP11-2C24.4
chr4_+_84457529 0.68 ENST00000264409.4
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr2_+_162165038 0.68 ENST00000437630.1
PSMD14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr12_-_122238464 0.66 ENST00000546227.1
RHOF
ras homolog family member F (in filopodia)
chr16_+_67312049 0.65 ENST00000565899.1
PLEKHG4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr11_-_8739383 0.65 ENST00000531060.1
ST5
suppression of tumorigenicity 5
chr5_+_147582387 0.62 ENST00000325630.2
SPINK6
serine peptidase inhibitor, Kazal type 6
chr17_+_21191341 0.60 ENST00000526076.2
ENST00000361818.5
ENST00000316920.6
MAP2K3
mitogen-activated protein kinase kinase 3
chr5_+_177540444 0.58 ENST00000274605.5
N4BP3
NEDD4 binding protein 3
chr6_-_44233361 0.57 ENST00000275015.5
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chrX_-_48937684 0.56 ENST00000465382.1
ENST00000423215.2
WDR45
WD repeat domain 45
chr1_-_113247543 0.56 ENST00000414971.1
ENST00000534717.1
RHOC
ras homolog family member C
chr12_+_13349711 0.54 ENST00000538364.1
ENST00000396301.3
EMP1
epithelial membrane protein 1
chr9_+_140135665 0.54 ENST00000340384.4
TUBB4B
tubulin, beta 4B class IVb
chr9_-_127177703 0.53 ENST00000259457.3
ENST00000536392.1
ENST00000441097.1
PSMB7
proteasome (prosome, macropain) subunit, beta type, 7
chr16_+_30077098 0.52 ENST00000395240.3
ENST00000566846.1
ALDOA
aldolase A, fructose-bisphosphate
chr8_-_82395461 0.52 ENST00000256104.4
FABP4
fatty acid binding protein 4, adipocyte
chr12_-_48152853 0.52 ENST00000171000.4
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr2_-_220117867 0.51 ENST00000456818.1
ENST00000447205.1
TUBA4A
tubulin, alpha 4a
chr9_-_35112376 0.50 ENST00000488109.2
FAM214B
family with sequence similarity 214, member B
chr17_-_39780819 0.49 ENST00000311208.8
KRT17
keratin 17
chr8_+_126442563 0.48 ENST00000311922.3
TRIB1
tribbles pseudokinase 1
chr17_-_18908040 0.48 ENST00000388995.6
FAM83G
family with sequence similarity 83, member G
chr17_+_9745786 0.48 ENST00000304773.5
GLP2R
glucagon-like peptide 2 receptor
chr4_+_76481258 0.47 ENST00000311623.4
ENST00000435974.2
C4orf26
chromosome 4 open reading frame 26
chr1_+_183155373 0.46 ENST00000493293.1
ENST00000264144.4
LAMC2
laminin, gamma 2
chr12_+_10365082 0.46 ENST00000545859.1
GABARAPL1
GABA(A) receptor-associated protein like 1
chr12_-_54813229 0.45 ENST00000293379.4
ITGA5
integrin, alpha 5 (fibronectin receptor, alpha polypeptide)
chr16_+_2083265 0.45 ENST00000565855.1
ENST00000566198.1
SLC9A3R2
solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
chr19_+_50706866 0.44 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
MYH14
myosin, heavy chain 14, non-muscle
chr10_-_4285835 0.43 ENST00000454470.1
LINC00702
long intergenic non-protein coding RNA 702
chr13_+_78109804 0.43 ENST00000535157.1
SCEL
sciellin
chr19_-_6057282 0.42 ENST00000592281.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr9_+_140119618 0.42 ENST00000359069.2
C9orf169
chromosome 9 open reading frame 169
chr19_-_51523412 0.42 ENST00000391805.1
ENST00000599077.1
KLK10
kallikrein-related peptidase 10
chr19_-_51538118 0.42 ENST00000529888.1
KLK12
kallikrein-related peptidase 12
chr9_-_35111570 0.41 ENST00000378561.1
ENST00000603301.1
FAM214B
family with sequence similarity 214, member B
chr17_-_73781567 0.41 ENST00000586607.1
H3F3B
H3 histone, family 3B (H3.3B)
chr12_+_7023735 0.41 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
ENO2
enolase 2 (gamma, neuronal)
chr1_+_36621174 0.41 ENST00000429533.2
MAP7D1
MAP7 domain containing 1
chr9_+_131902346 0.41 ENST00000432124.1
ENST00000435305.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr3_+_30648066 0.40 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr17_-_39781054 0.40 ENST00000463128.1
KRT17
keratin 17
chr10_-_106240032 0.40 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr20_+_48429356 0.40 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr16_-_66968265 0.40 ENST00000567511.1
ENST00000422424.2
FAM96B
family with sequence similarity 96, member B
chr17_+_65375082 0.40 ENST00000584471.1
PITPNC1
phosphatidylinositol transfer protein, cytoplasmic 1
chr19_-_51523275 0.40 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr6_-_161695042 0.40 ENST00000366908.5
ENST00000366911.5
ENST00000366905.3
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr14_+_94492674 0.39 ENST00000203664.5
ENST00000553723.1
OTUB2
OTU domain, ubiquitin aldehyde binding 2
chr11_-_9025541 0.39 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
NRIP3
nuclear receptor interacting protein 3
chr5_-_141061777 0.39 ENST00000239440.4
ARAP3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr17_-_79481666 0.39 ENST00000575659.1
ACTG1
actin, gamma 1
chr10_-_90611566 0.39 ENST00000371930.4
ANKRD22
ankyrin repeat domain 22
chr17_+_7255208 0.39 ENST00000333751.3
KCTD11
potassium channel tetramerization domain containing 11
chr9_+_34992846 0.39 ENST00000443266.1
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr19_+_35645618 0.39 ENST00000392218.2
ENST00000543307.1
ENST00000392219.2
ENST00000541435.2
ENST00000590686.1
ENST00000342879.3
ENST00000588699.1
FXYD5
FXYD domain containing ion transport regulator 5
chr11_-_102401469 0.38 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr10_+_75668916 0.38 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr1_+_36621529 0.38 ENST00000316156.4
MAP7D1
MAP7 domain containing 1
chr1_-_28520447 0.38 ENST00000539896.1
PTAFR
platelet-activating factor receptor
chr11_+_128563652 0.38 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr20_-_62129163 0.38 ENST00000298049.7
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr11_-_10920714 0.38 ENST00000533941.1
CTD-2003C8.2
CTD-2003C8.2
chr5_+_35852797 0.38 ENST00000508941.1
IL7R
interleukin 7 receptor
chr6_+_106534192 0.37 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr5_+_38148582 0.37 ENST00000508853.1
CTD-2207A17.1
CTD-2207A17.1
chr11_+_12308447 0.37 ENST00000256186.2
MICALCL
MICAL C-terminal like
chr12_+_7023491 0.37 ENST00000541477.1
ENST00000229277.1
ENO2
enolase 2 (gamma, neuronal)
chr9_-_130341268 0.37 ENST00000373314.3
FAM129B
family with sequence similarity 129, member B
chr1_+_36621697 0.37 ENST00000373150.4
ENST00000373151.2
MAP7D1
MAP7 domain containing 1
chrX_-_19689106 0.37 ENST00000379716.1
SH3KBP1
SH3-domain kinase binding protein 1
chr11_+_73000449 0.36 ENST00000535931.1
P2RY6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr2_+_135596180 0.36 ENST00000283054.4
ENST00000392928.1
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chrX_-_48937503 0.36 ENST00000322995.8
WDR45
WD repeat domain 45
chr15_-_72521017 0.36 ENST00000561609.1
PKM
pyruvate kinase, muscle
chr8_-_95220775 0.35 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17
cadherin 17, LI cadherin (liver-intestine)
chr7_+_150065278 0.35 ENST00000519397.1
ENST00000479668.1
ENST00000540729.1
REPIN1
replication initiator 1
chr9_-_35111420 0.35 ENST00000378557.1
FAM214B
family with sequence similarity 214, member B
chr12_-_91573249 0.35 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr10_-_47181681 0.35 ENST00000452267.1
FAM25B
family with sequence similarity 25, member B
chr2_+_202122826 0.35 ENST00000413726.1
CASP8
caspase 8, apoptosis-related cysteine peptidase
chr16_-_74330612 0.35 ENST00000569389.1
ENST00000562888.1
AC009120.4
AC009120.4
chr16_-_2908155 0.34 ENST00000571228.1
ENST00000161006.3
PRSS22
protease, serine, 22
chr6_-_161695074 0.34 ENST00000457520.2
ENST00000366906.5
ENST00000320285.4
AGPAT4
1-acylglycerol-3-phosphate O-acyltransferase 4
chr19_+_50431959 0.34 ENST00000595125.1
ATF5
activating transcription factor 5
chr19_+_35645817 0.34 ENST00000423817.3
FXYD5
FXYD domain containing ion transport regulator 5
chr11_-_2950642 0.34 ENST00000314222.4
PHLDA2
pleckstrin homology-like domain, family A, member 2
chr14_-_94854926 0.33 ENST00000402629.1
ENST00000556091.1
ENST00000554720.1
SERPINA1
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr12_-_48152611 0.33 ENST00000389212.3
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr11_+_10476851 0.33 ENST00000396553.2
AMPD3
adenosine monophosphate deaminase 3
chr4_-_122085469 0.33 ENST00000057513.3
TNIP3
TNFAIP3 interacting protein 3
chr19_-_18385221 0.33 ENST00000595654.2
ENST00000593659.1
ENST00000599528.1
KIAA1683
KIAA1683
chr7_-_130597935 0.33 ENST00000447307.1
ENST00000418546.1
MIR29B1
microRNA 29a
chr5_-_90610200 0.33 ENST00000511918.1
ENST00000513626.1
ENST00000607854.1
LUCAT1
RP11-213H15.4
lung cancer associated transcript 1 (non-protein coding)
RP11-213H15.4
chr1_+_150480551 0.32 ENST00000369049.4
ENST00000369047.4
ECM1
extracellular matrix protein 1
chr10_-_6019552 0.32 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
IL15RA
interleukin 15 receptor, alpha
chr1_-_155947951 0.32 ENST00000313695.7
ENST00000497907.1
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr1_-_45272951 0.32 ENST00000372200.1
TCTEX1D4
Tctex1 domain containing 4
chr2_+_113875466 0.31 ENST00000361779.3
ENST00000259206.5
ENST00000354115.2
IL1RN
interleukin 1 receptor antagonist
chr2_-_18770802 0.31 ENST00000416783.1
NT5C1B
5'-nucleotidase, cytosolic IB
chr3_-_51937331 0.31 ENST00000310914.5
IQCF1
IQ motif containing F1
chr16_+_58533951 0.31 ENST00000566192.1
ENST00000565088.1
ENST00000568640.1
ENST00000563978.1
ENST00000569923.1
ENST00000356752.4
ENST00000563799.1
ENST00000562999.1
ENST00000570248.1
ENST00000562731.1
ENST00000568424.1
NDRG4
NDRG family member 4
chr14_-_64970494 0.31 ENST00000608382.1
ZBTB25
zinc finger and BTB domain containing 25
chr2_-_224467002 0.31 ENST00000421386.1
ENST00000433889.1
SCG2
secretogranin II
chr10_+_30723533 0.31 ENST00000413724.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr10_+_48247669 0.31 ENST00000457620.1
FAM25G
family with sequence similarity 25, member G
chr2_+_220495800 0.31 ENST00000413743.1
SLC4A3
solute carrier family 4 (anion exchanger), member 3
chr1_+_27189631 0.31 ENST00000339276.4
SFN
stratifin
chr17_-_39780634 0.31 ENST00000577817.2
KRT17
keratin 17
chr5_+_150020240 0.30 ENST00000519664.1
SYNPO
synaptopodin
chr3_+_184016986 0.30 ENST00000417952.1
PSMD2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr1_+_27719148 0.30 ENST00000374024.3
GPR3
G protein-coupled receptor 3
chr15_+_41062159 0.30 ENST00000344320.6
C15orf62
chromosome 15 open reading frame 62
chr5_+_145317356 0.30 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr19_-_19739321 0.30 ENST00000588461.1
LPAR2
lysophosphatidic acid receptor 2
chr12_-_719573 0.30 ENST00000397265.3
NINJ2
ninjurin 2
chr1_+_169077133 0.30 ENST00000494797.1
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr5_-_75919253 0.29 ENST00000296641.4
F2RL2
coagulation factor II (thrombin) receptor-like 2
chr14_+_71108460 0.29 ENST00000256367.2
TTC9
tetratricopeptide repeat domain 9
chr1_-_109968973 0.29 ENST00000271308.4
ENST00000538610.1
PSMA5
proteasome (prosome, macropain) subunit, alpha type, 5
chr10_-_81708854 0.29 ENST00000372292.3
SFTPD
surfactant protein D
chr11_-_67141640 0.29 ENST00000533438.1
CLCF1
cardiotrophin-like cytokine factor 1
chr6_-_149806105 0.29 ENST00000389942.5
ENST00000416573.2
ENST00000542614.1
ENST00000409806.3
ZC3H12D
zinc finger CCCH-type containing 12D
chr16_-_66968055 0.29 ENST00000568572.1
FAM96B
family with sequence similarity 96, member B
chr9_-_91793675 0.29 ENST00000375835.4
ENST00000375830.1
SHC3
SHC (Src homology 2 domain containing) transforming protein 3
chr16_+_56782118 0.29 ENST00000566678.1
NUP93
nucleoporin 93kDa
chr15_-_83316254 0.29 ENST00000567678.1
ENST00000450751.2
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr1_-_154943212 0.29 ENST00000368445.5
ENST00000448116.2
ENST00000368449.4
SHC1
SHC (Src homology 2 domain containing) transforming protein 1
chr8_+_22844913 0.29 ENST00000519685.1
RHOBTB2
Rho-related BTB domain containing 2
chr7_+_102191679 0.29 ENST00000507918.1
ENST00000432940.1
SPDYE2
speedy/RINGO cell cycle regulator family member E2
chr16_-_31161380 0.29 ENST00000569305.1
ENST00000418068.2
ENST00000268281.4
PRSS36
protease, serine, 36
chr11_-_8739566 0.29 ENST00000533020.1
ST5
suppression of tumorigenicity 5
chr14_-_64971288 0.28 ENST00000394715.1
ZBTB25
zinc finger and BTB domain containing 25
chr17_+_26369865 0.28 ENST00000582037.1
NLK
nemo-like kinase
chr18_+_61637159 0.28 ENST00000397985.2
ENST00000353706.2
ENST00000542677.1
ENST00000397988.3
ENST00000448851.1
SERPINB8
serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr21_-_35340759 0.28 ENST00000607953.1
AP000569.9
AP000569.9
chrX_-_153718953 0.28 ENST00000369649.4
ENST00000393586.1
SLC10A3
solute carrier family 10, member 3
chr1_+_89990378 0.28 ENST00000449440.1
LRRC8B
leucine rich repeat containing 8 family, member B
chr18_+_32556892 0.28 ENST00000591734.1
ENST00000413393.1
ENST00000589180.1
ENST00000587359.1
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr3_+_30647994 0.27 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr18_+_55888767 0.27 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr17_-_1029052 0.27 ENST00000574437.1
ABR
active BCR-related
chr1_+_150480576 0.26 ENST00000346569.6
ECM1
extracellular matrix protein 1
chr2_-_218766698 0.26 ENST00000439083.1
TNS1
tensin 1
chr11_+_82783097 0.26 ENST00000501011.2
ENST00000527627.1
ENST00000526795.1
ENST00000533528.1
ENST00000533708.1
ENST00000534499.1
RAB30-AS1
RAB30 antisense RNA 1 (head to head)
chr14_+_69726864 0.26 ENST00000448469.3
GALNT16
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr8_-_56987057 0.26 ENST00000518875.1
RPS20
ribosomal protein S20
chr18_-_68004529 0.26 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr1_-_1009683 0.26 ENST00000453464.2
RNF223
ring finger protein 223

Network of associatons between targets according to the STRING database.

First level regulatory network of FOSL1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.3 GO:0034148 regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573) negative regulation of osteoclast proliferation(GO:0090291) negative regulation of CD40 signaling pathway(GO:2000349)
0.9 3.5 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.7 2.0 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.4 2.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.4 1.1 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.4 1.8 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.3 0.8 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.3 1.1 GO:0002268 follicular dendritic cell differentiation(GO:0002268)
0.3 2.4 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.3 1.3 GO:0018262 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.3 1.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2 0.7 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.2 0.7 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.2 0.6 GO:1904316 positive regulation of neutrophil degranulation(GO:0043315) cellular response to gravity(GO:0071258) positive regulation of neutrophil activation(GO:1902565) regulation of transcytosis(GO:1904298) positive regulation of transcytosis(GO:1904300) regulation of maternal process involved in parturition(GO:1904301) positive regulation of maternal process involved in parturition(GO:1904303) response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904316) cellular response to 2-O-acetyl-1-O-hexadecyl-sn-glycero-3-phosphocholine(GO:1904317)
0.2 1.4 GO:0007296 vitellogenesis(GO:0007296)
0.2 1.0 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.2 0.9 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.2 11.5 GO:0018149 peptide cross-linking(GO:0018149)
0.2 0.5 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.4 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.1 0.5 GO:0006218 uridine catabolic process(GO:0006218)
0.1 0.2 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.1 0.3 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) regulation of spongiotrophoblast cell proliferation(GO:0060721) cell proliferation involved in embryonic placenta development(GO:0060722) regulation of cell proliferation involved in embryonic placenta development(GO:0060723)
0.1 0.9 GO:0051546 keratinocyte migration(GO:0051546)
0.1 1.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.1 0.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.6 GO:1902766 skeletal muscle satellite cell migration(GO:1902766)
0.1 0.4 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.3 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.6 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 1.7 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.1 0.3 GO:0021966 corticospinal neuron axon guidance(GO:0021966)
0.1 0.3 GO:0060474 positive regulation of sperm motility involved in capacitation(GO:0060474)
0.1 0.2 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.4 GO:0001866 NK T cell proliferation(GO:0001866)
0.1 0.2 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 1.7 GO:0045109 intermediate filament organization(GO:0045109)
0.1 1.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.5 GO:1903281 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.1 0.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 1.1 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 0.3 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.4 GO:0098886 modification of dendritic spine(GO:0098886)
0.1 0.6 GO:0007320 insemination(GO:0007320)
0.1 0.2 GO:0033037 polysaccharide localization(GO:0033037)
0.1 0.3 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.1 0.1 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.1 0.6 GO:0035897 proteolysis in other organism(GO:0035897)
0.1 0.3 GO:0039516 modulation by virus of host molecular function(GO:0039506) suppression by virus of host molecular function(GO:0039507) suppression by virus of host catalytic activity(GO:0039513) modulation by virus of host catalytic activity(GO:0039516) suppression by virus of host cysteine-type endopeptidase activity involved in apoptotic process(GO:0039650) negative regulation by symbiont of host catalytic activity(GO:0052053) negative regulation by symbiont of host molecular function(GO:0052056) modulation by symbiont of host catalytic activity(GO:0052148)
0.1 0.6 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.4 GO:0052428 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.3 GO:0006196 AMP catabolic process(GO:0006196)
0.0 1.0 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.3 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.3 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.3 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:0032796 uropod organization(GO:0032796)
0.0 0.3 GO:0007044 cell-substrate junction assembly(GO:0007044)
0.0 0.4 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 1.0 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.4 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.3 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.2 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 0.1 GO:1901656 glycoside transport(GO:1901656)
0.0 0.3 GO:1902564 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of neutrophil activation(GO:1902564)
0.0 0.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 1.0 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.7 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.6 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.7 GO:0016024 CDP-diacylglycerol biosynthetic process(GO:0016024)
0.0 0.2 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0002372 myeloid dendritic cell cytokine production(GO:0002372)
0.0 1.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)
0.0 0.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.2 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.7 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.7 GO:0032060 bleb assembly(GO:0032060)
0.0 0.4 GO:0044849 estrous cycle(GO:0044849)
0.0 0.1 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.4 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.2 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.0 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 1.2 GO:0072348 sulfur compound transport(GO:0072348)
0.0 0.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.1 GO:0048016 inositol phosphate-mediated signaling(GO:0048016)
0.0 0.5 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.2 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 1.6 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.3 GO:0015886 heme transport(GO:0015886)
0.0 0.7 GO:0030728 ovulation(GO:0030728)
0.0 0.3 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.0 0.4 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.0 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.1 GO:0046521 sphingoid catabolic process(GO:0046521)
0.0 0.4 GO:1903543 positive regulation of exosomal secretion(GO:1903543)
0.0 0.3 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:0018202 peptidyl-histidine modification(GO:0018202)
0.0 0.3 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.7 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.5 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.6 GO:0061621 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.3 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.0 GO:0002118 aggressive behavior(GO:0002118) amygdala development(GO:0021764)
0.0 0.3 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.2 GO:0044130 negative regulation of growth of symbiont in host(GO:0044130)
0.0 0.0 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300) regulation of intestinal lipid absorption(GO:1904729)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 1.5 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.0 0.2 GO:0051451 myoblast migration(GO:0051451)
0.0 0.3 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.3 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.1 GO:0045907 positive regulation of vasoconstriction(GO:0045907)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.3 1.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.2 0.8 GO:0005607 laminin-2 complex(GO:0005607)
0.2 12.0 GO:0001533 cornified envelope(GO:0001533)
0.1 0.4 GO:0071062 alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.4 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.1 0.4 GO:0097444 spine apparatus(GO:0097444)
0.1 0.7 GO:0071817 MMXD complex(GO:0071817)
0.1 0.7 GO:0097513 myosin II filament(GO:0097513)
0.1 0.3 GO:0034515 proteasome storage granule(GO:0034515)
0.1 0.3 GO:1902912 pyruvate kinase complex(GO:1902912)
0.1 0.5 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.6 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.3 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.7 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 0.4 GO:0033565 ESCRT-0 complex(GO:0033565)
0.1 0.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.6 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 1.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 4.1 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.4 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:1990037 Lewy body core(GO:1990037)
0.0 0.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.1 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.4 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.4 GO:0009986 cell surface(GO:0009986)
0.0 0.4 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.5 GO:0031045 dense core granule(GO:0031045)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.7 GO:0032590 dendrite membrane(GO:0032590)
0.0 3.2 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.3 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 1.5 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.0 0.1 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.2 GO:0030056 hemidesmosome(GO:0030056)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.6 1.8 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.5 4.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.4 1.2 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.4 3.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.3 5.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 0.7 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.2 0.3 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.1 1.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.5 GO:0004967 glucagon receptor activity(GO:0004967)
0.1 0.3 GO:0005427 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.1 1.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.6 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.5 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.5 GO:0004992 platelet activating factor receptor activity(GO:0004992)
0.1 0.3 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.1 0.3 GO:0004743 pyruvate kinase activity(GO:0004743)
0.1 0.3 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.1 0.3 GO:0032551 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.6 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 2.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.4 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.2 GO:0015432 bile acid-exporting ATPase activity(GO:0015432)
0.1 1.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.1 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.2 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.2 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 0.4 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.9 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.3 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.7 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.2 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.3 GO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097199)
0.0 0.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.4 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 2.0 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.2 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 8.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.1 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0052839 inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.4 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.2 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.7 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 1.1 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.5 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.6 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 2.6 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0003924 GTPase activity(GO:0003924)
0.0 3.1 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 0.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.3 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 15.8 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 6.9 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.1 2.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.9 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 1.0 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.5 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.9 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 1.3 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 0.3 PID REELIN PATHWAY Reelin signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 4.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 5.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 0.6 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 3.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 1.5 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 1.5 REACTOME TAK1 ACTIVATES NFKB BY PHOSPHORYLATION AND ACTIVATION OF IKKS COMPLEX Genes involved in TAK1 activates NFkB by phosphorylation and activation of IKKs complex
0.1 2.6 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.1 2.2 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.1 1.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 2.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.8 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.6 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 1.0 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 2.2 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.6 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.5 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 2.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.8 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 2.3 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.6 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening