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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EZH2

Z-value: 1.39

Motif logo

Transcription factors associated with EZH2

Gene Symbol Gene ID Gene Info
ENSG00000106462.6 EZH2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EZH2hg19_v2_chr7_-_148581251_148581347-0.901.4e-02Click!

Activity profile of EZH2 motif

Sorted Z-values of EZH2 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of EZH2

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr7_-_41740181 2.14 ENST00000442711.1
INHBA
inhibin, beta A
chr6_-_31550192 1.45 ENST00000429299.2
ENST00000446745.2
LTB
lymphotoxin beta (TNF superfamily, member 3)
chr12_+_7167980 1.27 ENST00000360817.5
ENST00000402681.3
C1S
complement component 1, s subcomponent
chrY_+_15418467 1.26 ENST00000595988.1
AC010877.1
Uncharacterized protein
chr6_+_31543334 1.23 ENST00000449264.2
TNF
tumor necrosis factor
chr2_+_228678550 1.03 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr5_+_92919043 0.99 ENST00000327111.3
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr2_+_45168875 0.98 ENST00000260653.3
SIX3
SIX homeobox 3
chr6_+_31895467 0.94 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr6_+_31895480 0.85 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr6_+_31730773 0.79 ENST00000415669.2
ENST00000425424.1
SAPCD1
suppressor APC domain containing 1
chr5_-_146461027 0.76 ENST00000394410.2
ENST00000508267.1
ENST00000504198.1
PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr11_-_66496655 0.72 ENST00000527010.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chrX_+_28605516 0.62 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr12_+_120502441 0.62 ENST00000446727.2
CCDC64
coiled-coil domain containing 64
chr17_+_7533439 0.60 ENST00000441599.2
ENST00000380450.4
ENST00000416273.3
ENST00000575903.1
ENST00000576830.1
ENST00000571153.1
ENST00000575618.1
ENST00000576152.1
SHBG
sex hormone-binding globulin
chr11_-_102826434 0.57 ENST00000340273.4
ENST00000260302.3
MMP13
matrix metallopeptidase 13 (collagenase 3)
chrX_+_48681768 0.54 ENST00000430858.1
HDAC6
histone deacetylase 6
chr5_-_40835303 0.54 ENST00000509877.1
ENST00000508493.1
ENST00000274242.5
RPL37
ribosomal protein L37
chr2_-_113594279 0.53 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr7_-_117512264 0.52 ENST00000454375.1
CTTNBP2
cortactin binding protein 2
chr19_-_35626104 0.52 ENST00000310123.3
ENST00000392225.3
LGI4
leucine-rich repeat LGI family, member 4
chrX_-_100662881 0.51 ENST00000218516.3
GLA
galactosidase, alpha
chr17_-_76356148 0.50 ENST00000587578.1
ENST00000330871.2
SOCS3
suppressor of cytokine signaling 3
chr8_-_42065075 0.49 ENST00000429089.2
ENST00000519510.1
ENST00000429710.2
ENST00000524009.1
PLAT
plasminogen activator, tissue
chr12_-_7244469 0.49 ENST00000538050.1
ENST00000536053.2
C1R
complement component 1, r subcomponent
chr17_+_38334501 0.47 ENST00000541245.1
RAPGEFL1
Rap guanine nucleotide exchange factor (GEF)-like 1
chr17_-_73285293 0.47 ENST00000582778.1
ENST00000581988.1
ENST00000579207.1
ENST00000583332.1
ENST00000416858.2
ENST00000442286.2
ENST00000580151.1
ENST00000580994.1
ENST00000584438.1
ENST00000320362.3
ENST00000580273.1
SLC25A19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chr11_+_64004888 0.46 ENST00000541681.1
VEGFB
vascular endothelial growth factor B
chr4_+_74735102 0.45 ENST00000395761.3
CXCL1
chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chrX_-_48326764 0.45 ENST00000413668.1
ENST00000441948.1
SLC38A5
solute carrier family 38, member 5
chr1_+_152881014 0.44 ENST00000368764.3
ENST00000392667.2
IVL
involucrin
chr11_+_123430948 0.44 ENST00000529432.1
ENST00000534764.1
GRAMD1B
GRAM domain containing 1B
chr15_-_43559055 0.44 ENST00000220420.5
ENST00000349114.4
TGM5
transglutaminase 5
chr17_-_76719638 0.43 ENST00000587308.1
CYTH1
cytohesin 1
chr3_-_195538760 0.43 ENST00000475231.1
MUC4
mucin 4, cell surface associated
chr9_-_33402506 0.42 ENST00000377425.4
ENST00000537089.1
ENST00000297988.1
ENST00000539936.1
ENST00000541274.1
AQP7
aquaporin 7
chr12_+_113376249 0.42 ENST00000551007.1
ENST00000548514.1
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr8_+_55467072 0.42 ENST00000602362.1
RP11-53M11.3
RP11-53M11.3
chr12_+_113376157 0.42 ENST00000228928.7
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr8_+_61592073 0.42 ENST00000526846.1
CHD7
chromodomain helicase DNA binding protein 7
chr1_-_155112883 0.41 ENST00000368399.1
ENST00000368400.4
ENST00000341298.3
DPM3
dolichyl-phosphate mannosyltransferase polypeptide 3
chr2_-_31637560 0.41 ENST00000379416.3
XDH
xanthine dehydrogenase
chr16_+_31483451 0.40 ENST00000565360.1
ENST00000361773.3
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr10_-_106240032 0.40 ENST00000447860.1
RP11-127O4.3
RP11-127O4.3
chr16_+_58033450 0.40 ENST00000561743.1
USB1
U6 snRNA biogenesis 1
chr12_+_7022909 0.40 ENST00000537688.1
ENO2
enolase 2 (gamma, neuronal)
chr1_+_154193643 0.39 ENST00000456325.1
UBAP2L
ubiquitin associated protein 2-like
chr7_-_124405681 0.39 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chrX_-_153141783 0.38 ENST00000458029.1
L1CAM
L1 cell adhesion molecule
chr12_-_116714564 0.37 ENST00000548743.1
MED13L
mediator complex subunit 13-like
chr6_+_32132360 0.37 ENST00000333845.6
ENST00000395512.1
ENST00000432129.1
EGFL8
EGF-like-domain, multiple 8
chr17_+_7387677 0.37 ENST00000322644.6
POLR2A
polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr6_+_13272904 0.36 ENST00000379335.3
ENST00000379329.1
PHACTR1
phosphatase and actin regulator 1
chr8_+_40010989 0.36 ENST00000315792.3
C8orf4
chromosome 8 open reading frame 4
chr6_+_12958137 0.35 ENST00000457702.2
ENST00000379345.2
PHACTR1
phosphatase and actin regulator 1
chr15_+_90544532 0.35 ENST00000268154.4
ZNF710
zinc finger protein 710
chr7_-_139756791 0.35 ENST00000489809.1
PARP12
poly (ADP-ribose) polymerase family, member 12
chr3_-_48229846 0.35 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A
cell division cycle 25A
chr17_-_46806540 0.35 ENST00000290295.7
HOXB13
homeobox B13
chr6_+_126240442 0.34 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr3_+_47324424 0.34 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18
kelch-like family member 18
chr19_-_51289436 0.34 ENST00000562076.1
CTD-2568A17.1
CTD-2568A17.1
chr3_-_197300194 0.34 ENST00000358186.2
ENST00000431056.1
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr1_+_95975672 0.34 ENST00000440116.2
ENST00000456933.1
RP11-286B14.1
RP11-286B14.1
chr17_+_38119216 0.34 ENST00000301659.4
GSDMA
gasdermin A
chr10_+_12391685 0.34 ENST00000378845.1
CAMK1D
calcium/calmodulin-dependent protein kinase ID
chr13_-_108518986 0.33 ENST00000375915.2
FAM155A
family with sequence similarity 155, member A
chr9_-_16870704 0.32 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2
basonuclin 2
chr10_-_75682535 0.32 ENST00000409178.1
C10orf55
chromosome 10 open reading frame 55
chr15_+_84906338 0.32 ENST00000512109.1
GOLGA6L4
golgin A6 family-like 4
chr9_+_130911723 0.32 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr5_+_149865377 0.32 ENST00000522491.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr6_-_134639180 0.32 ENST00000367858.5
SGK1
serum/glucocorticoid regulated kinase 1
chr10_+_91152303 0.32 ENST00000371804.3
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr5_-_147162078 0.31 ENST00000507386.1
JAKMIP2
janus kinase and microtubule interacting protein 2
chr14_-_45431091 0.31 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28
kelch-like family member 28
chr12_-_58159361 0.31 ENST00000546567.1
CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chrX_-_24665353 0.31 ENST00000379144.2
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr1_+_209859510 0.31 ENST00000367028.2
ENST00000261465.1
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chr5_-_20575959 0.31 ENST00000507958.1
CDH18
cadherin 18, type 2
chr16_-_11367452 0.30 ENST00000327157.2
PRM3
protamine 3
chr17_+_27047570 0.30 ENST00000472628.1
ENST00000578181.1
RPL23A
ribosomal protein L23a
chr6_-_131277510 0.30 ENST00000525193.1
ENST00000527659.1
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr9_+_133971909 0.30 ENST00000247291.3
ENST00000372302.1
ENST00000372300.1
ENST00000372298.1
AIF1L
allograft inflammatory factor 1-like
chr3_+_109128961 0.30 ENST00000489670.1
RP11-702L6.4
RP11-702L6.4
chr9_-_116061476 0.30 ENST00000441031.3
RNF183
ring finger protein 183
chr14_-_94443105 0.30 ENST00000555019.1
ASB2
ankyrin repeat and SOCS box containing 2
chr6_+_12290586 0.29 ENST00000379375.5
EDN1
endothelin 1
chr1_+_154193325 0.29 ENST00000428931.1
ENST00000441890.1
ENST00000271877.7
ENST00000412596.1
ENST00000368504.1
ENST00000437652.1
UBAP2L
ubiquitin associated protein 2-like
chr15_-_65117807 0.29 ENST00000559239.1
ENST00000268043.4
ENST00000333425.6
PIF1
PIF1 5'-to-3' DNA helicase
chr12_-_49582978 0.29 ENST00000301071.7
TUBA1A
tubulin, alpha 1a
chr16_-_58033762 0.29 ENST00000299237.2
ZNF319
zinc finger protein 319
chr17_-_40134339 0.29 ENST00000587727.1
DNAJC7
DnaJ (Hsp40) homolog, subfamily C, member 7
chr3_+_109128837 0.29 ENST00000497996.1
RP11-702L6.4
RP11-702L6.4
chr11_+_114168773 0.29 ENST00000542647.1
ENST00000545255.1
NNMT
nicotinamide N-methyltransferase
chr19_-_7698599 0.28 ENST00000311069.5
PCP2
Purkinje cell protein 2
chr5_-_180235755 0.28 ENST00000502678.1
MGAT1
mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr8_+_128748308 0.28 ENST00000377970.2
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr6_-_31613280 0.28 ENST00000453833.1
BAG6
BCL2-associated athanogene 6
chr6_-_167276033 0.28 ENST00000503859.1
ENST00000506565.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_+_30848829 0.28 ENST00000508317.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr2_+_217363559 0.28 ENST00000600880.1
ENST00000446558.1
RPL37A
ribosomal protein L37a
chr19_-_39881669 0.28 ENST00000221266.7
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr9_+_131902283 0.28 ENST00000436883.1
ENST00000414510.1
PPP2R4
protein phosphatase 2A activator, regulatory subunit 4
chr10_+_30723105 0.28 ENST00000375322.2
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr12_-_49582593 0.28 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chrX_-_19688475 0.28 ENST00000541422.1
SH3KBP1
SH3-domain kinase binding protein 1
chr15_+_44084503 0.28 ENST00000409960.2
ENST00000409646.1
ENST00000594896.1
ENST00000339624.5
ENST00000409291.1
ENST00000402131.1
ENST00000403425.1
ENST00000430901.1
SERF2
small EDRK-rich factor 2
chr4_+_160188889 0.28 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr9_+_104296163 0.27 ENST00000374819.2
ENST00000479306.1
RNF20
ring finger protein 20, E3 ubiquitin protein ligase
chr5_+_175298674 0.27 ENST00000514150.1
CPLX2
complexin 2
chr12_-_7245018 0.27 ENST00000543835.1
ENST00000535233.2
C1R
complement component 1, r subcomponent
chr11_-_66496430 0.26 ENST00000533211.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chr5_+_147582348 0.26 ENST00000514389.1
SPINK6
serine peptidase inhibitor, Kazal type 6
chr17_-_7123021 0.26 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr21_+_17792672 0.26 ENST00000602620.1
LINC00478
long intergenic non-protein coding RNA 478
chr4_+_156588115 0.26 ENST00000455639.2
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr5_+_175298487 0.26 ENST00000393745.3
CPLX2
complexin 2
chrX_+_133941218 0.26 ENST00000370784.4
ENST00000370785.3
FAM122C
family with sequence similarity 122C
chr19_+_19303720 0.26 ENST00000392324.4
RFXANK
regulatory factor X-associated ankyrin-containing protein
chr4_+_156588249 0.26 ENST00000393832.3
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr6_-_79944336 0.26 ENST00000344726.5
ENST00000275036.7
HMGN3
high mobility group nucleosomal binding domain 3
chr16_+_30075783 0.26 ENST00000412304.2
ALDOA
aldolase A, fructose-bisphosphate
chr20_-_35580240 0.26 ENST00000262878.4
SAMHD1
SAM domain and HD domain 1
chr2_+_220462560 0.26 ENST00000456909.1
ENST00000295641.10
STK11IP
serine/threonine kinase 11 interacting protein
chr16_+_30709530 0.26 ENST00000411466.2
SRCAP
Snf2-related CREBBP activator protein
chr11_-_132813627 0.25 ENST00000374778.4
OPCML
opioid binding protein/cell adhesion molecule-like
chr16_-_58034357 0.25 ENST00000562909.1
ZNF319
zinc finger protein 319
chr10_+_1102303 0.25 ENST00000381329.1
WDR37
WD repeat domain 37
chr19_-_54604083 0.25 ENST00000391761.1
ENST00000356532.3
ENST00000359649.4
ENST00000358375.4
ENST00000391760.1
ENST00000351806.4
OSCAR
osteoclast associated, immunoglobulin-like receptor
chr5_+_140571902 0.25 ENST00000239446.4
PCDHB10
protocadherin beta 10
chr9_-_112970436 0.25 ENST00000400613.4
C9orf152
chromosome 9 open reading frame 152
chr13_-_72441315 0.25 ENST00000305425.4
ENST00000313174.7
ENST00000354591.4
DACH1
dachshund homolog 1 (Drosophila)
chr3_-_47324242 0.24 ENST00000456548.1
ENST00000432493.1
ENST00000335044.2
ENST00000444589.2
KIF9
kinesin family member 9
chr19_-_39881777 0.24 ENST00000595564.1
ENST00000221265.3
PAF1
Paf1, RNA polymerase II associated factor, homolog (S. cerevisiae)
chr16_-_30569584 0.24 ENST00000252797.2
ENST00000568114.1
ZNF764
AC002310.13
zinc finger protein 764
Uncharacterized protein
chr20_+_62795827 0.24 ENST00000328439.1
ENST00000536311.1
MYT1
myelin transcription factor 1
chr6_-_75915757 0.24 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chr3_-_120400960 0.24 ENST00000476082.2
HGD
homogentisate 1,2-dioxygenase
chr16_-_19725899 0.24 ENST00000567367.1
KNOP1
lysine-rich nucleolar protein 1
chr5_+_145317356 0.24 ENST00000511217.1
SH3RF2
SH3 domain containing ring finger 2
chr16_-_69419473 0.24 ENST00000566750.1
TERF2
telomeric repeat binding factor 2
chr11_-_65667884 0.24 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1
FOS-like antigen 1
chr14_-_81408031 0.23 ENST00000216517.6
CEP128
centrosomal protein 128kDa
chr10_+_18629628 0.23 ENST00000377329.4
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr9_-_71869642 0.23 ENST00000600472.1
AL358113.1
Tight junction protein 2 (Zona occludens 2) isoform 1 variant; Uncharacterized protein
chr15_+_43885799 0.23 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr17_+_77030267 0.23 ENST00000581774.1
C1QTNF1
C1q and tumor necrosis factor related protein 1
chr1_+_214161272 0.23 ENST00000498508.2
ENST00000366958.4
PROX1
prospero homeobox 1
chrY_-_15591485 0.23 ENST00000382896.4
ENST00000537580.1
ENST00000540140.1
ENST00000545955.1
ENST00000538878.1
UTY
ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
chr10_+_30723045 0.23 ENST00000542547.1
ENST00000415139.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chrX_+_69488174 0.23 ENST00000480877.2
ENST00000307959.8
ARR3
arrestin 3, retinal (X-arrestin)
chr11_+_60614946 0.23 ENST00000545580.1
CCDC86
coiled-coil domain containing 86
chr14_+_39703112 0.23 ENST00000555143.1
ENST00000280082.3
MIA2
melanoma inhibitory activity 2
chr16_+_30075595 0.23 ENST00000563060.2
ALDOA
aldolase A, fructose-bisphosphate
chr3_-_114173530 0.23 ENST00000470311.1
ZBTB20
zinc finger and BTB domain containing 20
chr4_-_80994471 0.23 ENST00000295465.4
ANTXR2
anthrax toxin receptor 2
chr16_+_54964740 0.22 ENST00000394636.4
IRX5
iroquois homeobox 5
chr17_+_18218587 0.22 ENST00000406438.3
SMCR8
Smith-Magenis syndrome chromosome region, candidate 8
chr8_+_128748466 0.22 ENST00000524013.1
ENST00000520751.1
MYC
v-myc avian myelocytomatosis viral oncogene homolog
chr12_-_49582837 0.22 ENST00000547939.1
ENST00000546918.1
ENST00000552924.1
TUBA1A
tubulin, alpha 1a
chr12_+_93965451 0.22 ENST00000548537.1
SOCS2
suppressor of cytokine signaling 2
chr7_+_100271355 0.22 ENST00000436220.1
ENST00000424361.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chrX_-_152989798 0.22 ENST00000441714.1
ENST00000442093.1
ENST00000429550.1
ENST00000345046.6
BCAP31
B-cell receptor-associated protein 31
chr19_-_4338783 0.22 ENST00000601482.1
ENST00000600324.1
STAP2
signal transducing adaptor family member 2
chr8_+_99956759 0.21 ENST00000522510.1
ENST00000457907.2
OSR2
odd-skipped related transciption factor 2
chr17_-_38928414 0.21 ENST00000335552.4
KRT26
keratin 26
chr10_+_75668916 0.21 ENST00000481390.1
PLAU
plasminogen activator, urokinase
chr3_-_116164306 0.21 ENST00000490035.2
LSAMP
limbic system-associated membrane protein
chr15_-_60695071 0.21 ENST00000557904.1
ANXA2
annexin A2
chr11_+_64053890 0.21 ENST00000438980.2
ENST00000313074.3
ENST00000542190.1
ENST00000541952.1
GPR137
G protein-coupled receptor 137
chr17_-_45918539 0.21 ENST00000584123.1
ENST00000578323.1
ENST00000407215.3
ENST00000290216.9
SCRN2
secernin 2
chr3_-_157823839 0.21 ENST00000425436.3
ENST00000389589.4
ENST00000441443.2
SHOX2
short stature homeobox 2
chr16_-_29934558 0.21 ENST00000568995.1
ENST00000566413.1
KCTD13
potassium channel tetramerization domain containing 13
chr4_+_84457250 0.21 ENST00000395226.2
AGPAT9
1-acylglycerol-3-phosphate O-acyltransferase 9
chr8_+_11666649 0.21 ENST00000528643.1
ENST00000525777.1
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr16_+_56782118 0.21 ENST00000566678.1
NUP93
nucleoporin 93kDa
chr17_-_46692287 0.21 ENST00000239144.4
HOXB8
homeobox B8
chr14_+_23305760 0.21 ENST00000311852.6
MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr16_+_30662085 0.21 ENST00000569864.1
PRR14
proline rich 14
chr16_+_30406423 0.21 ENST00000524644.1
ZNF48
zinc finger protein 48
chr6_+_30848771 0.21 ENST00000503180.1
DDR1
discoidin domain receptor tyrosine kinase 1
chr4_-_54457783 0.21 ENST00000263925.7
ENST00000512247.1
LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr14_+_92789498 0.21 ENST00000531433.1
SLC24A4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr6_-_24489842 0.20 ENST00000230036.1
GPLD1
glycosylphosphatidylinositol specific phospholipase D1
chr2_+_89952792 0.20 ENST00000390265.2
IGKV1D-33
immunoglobulin kappa variable 1D-33
chr6_-_42713792 0.20 ENST00000372876.1
TBCC
tubulin folding cofactor C
chr7_+_129251531 0.20 ENST00000393232.1
ENST00000353868.4
ENST00000539636.1
ENST00000454688.1
ENST00000223190.4
ENST00000311967.2
NRF1
nuclear respiratory factor 1
chrX_-_48815633 0.20 ENST00000428668.2
OTUD5
OTU domain containing 5
chr12_+_72058130 0.20 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr7_+_18330035 0.20 ENST00000413509.2
HDAC9
histone deacetylase 9
chr13_-_33859819 0.20 ENST00000336934.5
STARD13
StAR-related lipid transfer (START) domain containing 13
chr15_+_44084040 0.19 ENST00000249786.4
SERF2
small EDRK-rich factor 2
chr18_-_46784778 0.19 ENST00000582399.1
DYM
dymeclin
chr8_+_22857048 0.19 ENST00000251822.6
RHOBTB2
Rho-related BTB domain containing 2
chr11_-_115630900 0.19 ENST00000537070.1
ENST00000499809.1
ENST00000514294.2
ENST00000535683.1
LINC00900
long intergenic non-protein coding RNA 900
chr6_+_3259148 0.19 ENST00000419065.2
ENST00000473000.2
ENST00000451246.2
ENST00000454610.2
PSMG4
proteasome (prosome, macropain) assembly chaperone 4
chr1_+_45265897 0.19 ENST00000372201.4
PLK3
polo-like kinase 3
chr10_+_75670862 0.19 ENST00000446342.1
ENST00000372764.3
ENST00000372762.4
PLAU
plasminogen activator, urokinase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.4 1.2 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.4 1.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.3 1.0 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.2 1.4 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 1.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.5 GO:0070845 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.1 0.8 GO:0052565 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.1 0.5 GO:0090095 regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.7 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.1 0.3 GO:1900215 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) thyroid-stimulating hormone secretion(GO:0070460) kidney field specification(GO:0072004) DCT cell differentiation(GO:0072069) metanephric DCT cell differentiation(GO:0072240) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594) regulation of thyroid-stimulating hormone secretion(GO:2000612)
0.1 0.5 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.3 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.4 GO:0046110 xanthine metabolic process(GO:0046110)
0.1 0.5 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.7 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.1 1.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.3 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.2 GO:1900368 regulation of RNA interference(GO:1900368)
0.1 0.4 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 0.4 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.1 0.4 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.1 0.2 GO:0019836 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.4 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.1 0.2 GO:2001280 myoblast migration involved in skeletal muscle regeneration(GO:0014839) positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.3 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.2 GO:0072194 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) kidney smooth muscle tissue development(GO:0072194)
0.1 0.1 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.8 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 0.6 GO:0014805 smooth muscle adaptation(GO:0014805)
0.1 0.3 GO:0046061 dATP catabolic process(GO:0046061)
0.1 0.4 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.3 GO:0015891 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.1 0.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.1 1.0 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1 0.2 GO:0045726 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.5 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.2 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 0.2 GO:0032207 regulation of telomere maintenance via recombination(GO:0032207) negative regulation of telomere maintenance via recombination(GO:0032208) negative regulation of single strand break repair(GO:1903517) negative regulation of beta-galactosidase activity(GO:1903770) telomere single strand break repair(GO:1903823) negative regulation of telomere single strand break repair(GO:1903824)
0.1 0.4 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.2 GO:0045658 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.1 0.1 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 0.2 GO:0052416 multi-organism catabolic process(GO:0044035) development of symbiont involved in interaction with host(GO:0044115) modulation of development of symbiont involved in interaction with host(GO:0044145) negative regulation of development of symbiont involved in interaction with host(GO:0044147) metabolism of substance in other organism involved in symbiotic interaction(GO:0052214) catabolism of substance in other organism involved in symbiotic interaction(GO:0052227) metabolism of macromolecule in other organism involved in symbiotic interaction(GO:0052229) catabolism by host of symbiont macromolecule(GO:0052360) catabolism by organism of macromolecule in other organism involved in symbiotic interaction(GO:0052361) catabolism by host of symbiont protein(GO:0052362) catabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052363) catabolism by host of substance in symbiont(GO:0052364) metabolism by host of symbiont macromolecule(GO:0052416) metabolism by host of symbiont protein(GO:0052417) metabolism by organism of protein in other organism involved in symbiotic interaction(GO:0052418) metabolism by host of substance in symbiont(GO:0052419)
0.1 0.4 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.4 GO:0015793 glycerol transport(GO:0015793)
0.1 0.5 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.6 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.5 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.1 0.3 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.2 GO:0046586 regulation of calcium-dependent cell-cell adhesion(GO:0046586)
0.0 0.2 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.8 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.5 GO:0051001 glycoside catabolic process(GO:0016139) glycosylceramide catabolic process(GO:0046477) negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.2 GO:0002118 aggressive behavior(GO:0002118)
0.0 0.1 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365)
0.0 0.3 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.0 0.3 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0 0.3 GO:0046886 positive regulation of hormone biosynthetic process(GO:0046886)
0.0 0.2 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.0 0.1 GO:0021569 rhombomere 3 development(GO:0021569) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.0 0.2 GO:0008204 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.3 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.3 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.4 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.0 0.7 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.0 0.2 GO:1904044 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) response to aldosterone(GO:1904044)
0.0 0.4 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:1900276 regulation of proteinase activated receptor activity(GO:1900276) negative regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900737)
0.0 0.3 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:0071474 hyperosmotic response(GO:0006972) cellular hyperosmotic response(GO:0071474)
0.0 0.1 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of high-density lipoprotein particle clearance(GO:0010983)
0.0 0.6 GO:0015816 glycine transport(GO:0015816)
0.0 0.4 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.3 GO:0016098 monoterpenoid metabolic process(GO:0016098)
0.0 0.4 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.2 GO:0003185 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185)
0.0 0.5 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 1.3 GO:0003416 endochondral bone growth(GO:0003416)
0.0 0.2 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0051891 positive regulation of cardioblast differentiation(GO:0051891)
0.0 0.5 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.3 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.2 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.2 GO:0045007 depurination(GO:0045007)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.2 GO:1904879 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.6 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 0.3 GO:1904327 protein localization to cytosolic proteasome complex(GO:1904327) protein localization to cytosolic proteasome complex involved in ERAD pathway(GO:1904379)
0.0 0.1 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.0 0.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.1 GO:0003404 optic vesicle morphogenesis(GO:0003404) optic cup structural organization(GO:0003409) oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.0 0.3 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:1904808 regulation of protein oxidation(GO:1904806) positive regulation of protein oxidation(GO:1904808)
0.0 0.2 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0019249 lactate biosynthetic process(GO:0019249)
0.0 0.2 GO:1902952 positive regulation of dendritic spine maintenance(GO:1902952)
0.0 0.2 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.1 GO:0000706 meiotic DNA double-strand break processing(GO:0000706) double-strand break repair involved in meiotic recombination(GO:1990918)
0.0 0.4 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.3 GO:1901185 negative regulation of ERBB signaling pathway(GO:1901185)
0.0 0.1 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862) pathway-restricted SMAD protein phosphorylation(GO:0060389) regulation of pathway-restricted SMAD protein phosphorylation(GO:0060393)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.1 GO:0002368 B cell cytokine production(GO:0002368)
0.0 0.1 GO:1903412 response to bile acid(GO:1903412)
0.0 0.5 GO:0031639 plasminogen activation(GO:0031639)
0.0 0.1 GO:0035115 embryonic forelimb morphogenesis(GO:0035115)
0.0 0.2 GO:2000382 positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0043163 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.1 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.0 0.1 GO:0036060 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.3 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.2 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.1 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.3 GO:1902548 negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.0 0.1 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.1 GO:0072156 distal tubule morphogenesis(GO:0072156)
0.0 0.1 GO:1990167 protein K27-linked deubiquitination(GO:1990167)
0.0 0.3 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.1 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.4 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.0 0.4 GO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway(GO:0034356)
0.0 0.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.3 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0032690 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.0 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0 0.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.4 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.1 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197)
0.0 0.2 GO:0019344 cysteine biosynthetic process(GO:0019344)
0.0 0.1 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:0010669 epithelial structure maintenance(GO:0010669)
0.0 0.1 GO:1990834 response to odorant(GO:1990834)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.2 GO:0034382 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.0 0.2 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.2 GO:0046322 negative regulation of fatty acid oxidation(GO:0046322)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.1 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.0 0.1 GO:0021861 forebrain radial glial cell differentiation(GO:0021861)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.3 GO:0051412 response to corticosterone(GO:0051412)
0.0 0.1 GO:0010626 regulation of Schwann cell proliferation(GO:0010624) negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.4 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:1990785 response to water-immersion restraint stress(GO:1990785)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.1 GO:0021590 cerebellum maturation(GO:0021590) cerebellar Purkinje cell layer maturation(GO:0021691) cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:2001303 lipoxin biosynthetic process(GO:2001301) lipoxin A4 metabolic process(GO:2001302) lipoxin A4 biosynthetic process(GO:2001303)
0.0 0.2 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.0 0.0 GO:0071624 positive regulation of granulocyte chemotaxis(GO:0071624)
0.0 0.0 GO:0030073 insulin secretion(GO:0030073)
0.0 0.0 GO:0019074 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.0 0.2 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.2 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478) endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.1 GO:0035640 exploration behavior(GO:0035640)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019) negative regulation of gap junction assembly(GO:1903597)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.0 0.0 GO:0010958 regulation of amino acid import(GO:0010958) regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920)
0.0 0.0 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.1 GO:0099551 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.1 GO:1901631 postsynaptic membrane assembly(GO:0097104) neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118) positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.6 GO:0050911 detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0 0.1 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.0 GO:0048205 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.2 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.1 GO:0070092 regulation of glucagon secretion(GO:0070092)
0.0 0.1 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.0 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.1 GO:0033523 histone H2B ubiquitination(GO:0033523)
0.0 0.0 GO:1903445 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.0 GO:0061055 myotome development(GO:0061055)
0.0 0.4 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.1 GO:0010819 regulation of T cell chemotaxis(GO:0010819) positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.2 GO:0006929 substrate-dependent cell migration(GO:0006929)
0.0 0.2 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.4 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.6 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033) synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex(GO:0070554)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.2 GO:0005595 collagen type XII trimer(GO:0005595)
0.1 1.4 GO:0008091 spectrin(GO:0008091)
0.1 0.3 GO:0005600 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 0.2 GO:0042565 nuclear RNA export factor complex(GO:0042272) RNA nuclear export complex(GO:0042565)
0.1 0.4 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.1 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 0.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.2 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.1 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.2 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.1 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 1.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0033011 perinuclear theca(GO:0033011)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.2 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.0 0.3 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.4 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0072517 viral factory(GO:0039713) cytoplasmic viral factory(GO:0039714) host cell viral assembly compartment(GO:0072517)
0.0 0.1 GO:0043257 laminin-8 complex(GO:0043257)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.4 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 0.1 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.0 0.7 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.2 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.3 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.4 GO:0000974 Prp19 complex(GO:0000974)
0.0 4.0 GO:0072562 blood microparticle(GO:0072562)
0.0 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.1 GO:1990423 RZZ complex(GO:1990423)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.3 GO:0098647 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.2 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.0 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.4 GO:0031932 TORC2 complex(GO:0031932)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.1 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.0 0.2 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 1.2 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0000835 ER ubiquitin ligase complex(GO:0000835)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.1 GO:0038201 TORC1 complex(GO:0031931) TOR complex(GO:0038201)
0.0 0.6 GO:0000786 nucleosome(GO:0000786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0034711 inhibin binding(GO:0034711)
0.3 1.0 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.1 0.5 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.9 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 0.3 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.5 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.1 0.4 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.3 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.3 GO:0031705 bombesin receptor binding(GO:0031705)
0.1 0.3 GO:0017116 single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677)
0.1 0.4 GO:0030760 nicotinamide N-methyltransferase activity(GO:0008112) pyridine N-methyltransferase activity(GO:0030760)
0.1 0.5 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.1 0.3 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.5 GO:0016936 galactoside binding(GO:0016936)
0.1 0.4 GO:0015254 glycerol channel activity(GO:0015254)
0.1 0.3 GO:0004996 thyroid-stimulating hormone receptor activity(GO:0004996)
0.1 0.4 GO:0002046 opsin binding(GO:0002046)
0.1 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.3 GO:0004874 aryl hydrocarbon receptor activity(GO:0004874)
0.1 0.8 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.2 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.2 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.2 GO:0032408 MutLbeta complex binding(GO:0032406) MutSbeta complex binding(GO:0032408)
0.1 0.6 GO:0005497 androgen binding(GO:0005497)
0.1 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 2.0 GO:0001848 complement binding(GO:0001848)
0.1 0.3 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.1 0.7 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.2 GO:0004310 farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996)
0.0 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.5 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.3 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0016211 glutamate-ammonia ligase activity(GO:0004356) ammonia ligase activity(GO:0016211) acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.4 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.6 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.5 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.7 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.3 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.9 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.5 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.3 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.0 0.1 GO:0035651 AP-1 adaptor complex binding(GO:0035650) AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.3 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 1.4 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0004447 iodide peroxidase activity(GO:0004447)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.9 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.5 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.9 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.1 GO:0086040 sodium:proton antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086040)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.3 GO:0042731 PH domain binding(GO:0042731)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015) laminin-1 binding(GO:0043237)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0042835 BRE binding(GO:0042835)
0.0 0.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0016774 phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.7 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0003720 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.0 GO:0035034 histone acetyltransferase regulator activity(GO:0035034)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 3.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.1 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.0 GO:0003953 NAD+ nucleosidase activity(GO:0003953) NAD(P)+ nucleosidase activity(GO:0050135)
0.0 0.2 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.1 GO:0047977 linoleate 13S-lipoxygenase activity(GO:0016165) hepoxilin-epoxide hydrolase activity(GO:0047977)
0.0 0.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.0 GO:0008240 tripeptidyl-peptidase activity(GO:0008240) bradykinin receptor binding(GO:0031711)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.6 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.2 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.0 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.1 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 2.1 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.2 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.7 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.7 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.1 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.8 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID CD40 PATHWAY CD40/CD40L signaling
0.0 1.0 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.8 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.9 PID ATR PATHWAY ATR signaling pathway
0.0 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 2.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 1.9 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 1.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME OPSINS Genes involved in Opsins
0.0 1.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma
0.0 1.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 1.0 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.0 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.0 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 1.1 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.7 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)