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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for ESR1

Z-value: 1.15

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Transcription factors associated with ESR1

Gene Symbol Gene ID Gene Info
ESR1
ENSG00000091831.17 estrogen receptor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
ESR1hg19_v2_chr6_+_152128810_152128827-0.236.7e-01Click!

Activity profile of ESR1 motif

Sorted Z-values of ESR1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_3137080 0.79 ENST00000574387.1
ENST00000571404.1
RP11-473M20.9
RP11-473M20.9
chr2_-_241396131 0.68 ENST00000404327.3
AC110619.2
Uncharacterized protein
chr2_-_42588289 0.60 ENST00000468711.1
ENST00000463055.1
COX7A2L
cytochrome c oxidase subunit VIIa polypeptide 2 like
chr14_+_94577074 0.60 ENST00000444961.1
ENST00000448882.1
ENST00000557098.1
ENST00000554800.1
ENST00000556544.1
ENST00000298902.5
ENST00000555819.1
ENST00000557634.1
ENST00000555744.1
IFI27
interferon, alpha-inducible protein 27
chr7_+_106415457 0.59 ENST00000490162.2
ENST00000470135.1
RP5-884M6.1
RP5-884M6.1
chr17_+_63096903 0.54 ENST00000582940.1
RP11-160O5.1
RP11-160O5.1
chr8_-_30013748 0.50 ENST00000607315.1
RP11-51J9.5
RP11-51J9.5
chr16_+_28857957 0.49 ENST00000567536.1
SH2B1
SH2B adaptor protein 1
chr5_-_154230130 0.47 ENST00000519501.1
ENST00000518651.1
ENST00000517938.1
ENST00000520461.1
FAXDC2
fatty acid hydroxylase domain containing 2
chr11_-_47270341 0.46 ENST00000529444.1
ENST00000530453.1
ENST00000537863.1
ENST00000529788.1
ENST00000444355.2
ENST00000527256.1
ENST00000529663.1
ENST00000256997.3
ACP2
acid phosphatase 2, lysosomal
chr14_+_106384295 0.45 ENST00000449410.1
ENST00000429431.1
KIAA0125
KIAA0125
chr5_+_172484377 0.43 ENST00000523161.1
CREBRF
CREB3 regulatory factor
chr14_-_105531759 0.43 ENST00000329797.3
ENST00000539291.2
ENST00000392585.2
GPR132
G protein-coupled receptor 132
chr13_-_103451307 0.43 ENST00000376004.4
KDELC1
KDEL (Lys-Asp-Glu-Leu) containing 1
chr5_-_110074603 0.43 ENST00000515278.2
TMEM232
transmembrane protein 232
chr19_-_18717627 0.38 ENST00000392386.3
CRLF1
cytokine receptor-like factor 1
chr6_-_32122106 0.37 ENST00000428778.1
PRRT1
proline-rich transmembrane protein 1
chr8_-_144099795 0.37 ENST00000522060.1
ENST00000517833.1
ENST00000502167.2
ENST00000518831.1
RP11-273G15.2
RP11-273G15.2
chr19_-_46000251 0.37 ENST00000590526.1
ENST00000344680.4
ENST00000245923.4
RTN2
reticulon 2
chr19_+_7011509 0.36 ENST00000377296.3
AC025278.1
Uncharacterized protein
chr10_-_48332197 0.35 ENST00000454672.1
RP11-463P17.1
RP11-463P17.1
chr8_-_101661887 0.34 ENST00000311812.2
SNX31
sorting nexin 31
chr16_-_28608424 0.34 ENST00000335715.4
SULT1A2
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 2
chr2_-_241396106 0.32 ENST00000404891.1
AC110619.2
Uncharacterized protein
chr19_-_59010565 0.32 ENST00000594786.1
SLC27A5
solute carrier family 27 (fatty acid transporter), member 5
chr8_-_144691718 0.31 ENST00000377579.3
ENST00000433751.1
ENST00000220966.6
PYCRL
pyrroline-5-carboxylate reductase-like
chr1_-_917497 0.29 ENST00000433179.2
C1orf170
chromosome 1 open reading frame 170
chr1_-_153433120 0.29 ENST00000368723.3
S100A7
S100 calcium binding protein A7
chr16_+_75182376 0.29 ENST00000570010.1
ENST00000568079.1
ENST00000464850.1
ENST00000332307.4
ENST00000393430.2
ZFP1
ZFP1 zinc finger protein
chr17_-_73285293 0.28 ENST00000582778.1
ENST00000581988.1
ENST00000579207.1
ENST00000583332.1
ENST00000416858.2
ENST00000442286.2
ENST00000580151.1
ENST00000580994.1
ENST00000584438.1
ENST00000320362.3
ENST00000580273.1
SLC25A19
solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19
chrX_+_38420623 0.28 ENST00000378482.2
TSPAN7
tetraspanin 7
chr3_+_15469058 0.28 ENST00000432764.2
EAF1
ELL associated factor 1
chr14_+_62331592 0.28 ENST00000554436.1
CTD-2277K2.1
CTD-2277K2.1
chr4_-_89079817 0.28 ENST00000505480.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr1_-_47655686 0.28 ENST00000294338.2
PDZK1IP1
PDZK1 interacting protein 1
chr19_-_54824344 0.28 ENST00000346508.3
ENST00000446712.3
ENST00000432233.3
ENST00000301219.3
LILRA5
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 5
chr11_-_64527425 0.28 ENST00000377432.3
PYGM
phosphorylase, glycogen, muscle
chr7_+_99156011 0.27 ENST00000320583.5
ENST00000357864.2
ZNF655
zinc finger protein 655
chr2_+_231090433 0.27 ENST00000486687.2
ENST00000350136.5
ENST00000392045.3
ENST00000417495.3
ENST00000343805.6
ENST00000420434.3
SP140
SP140 nuclear body protein
chr16_-_3306587 0.27 ENST00000541159.1
ENST00000536379.1
ENST00000219596.1
ENST00000339854.4
MEFV
Mediterranean fever
chr12_+_123874589 0.27 ENST00000437502.1
SETD8
SET domain containing (lysine methyltransferase) 8
chr22_-_20138302 0.27 ENST00000540078.1
ENST00000439765.2
AC006547.14
uncharacterized protein LOC388849
chr15_-_76352069 0.26 ENST00000305435.10
ENST00000563910.1
NRG4
neuregulin 4
chr20_+_48429356 0.25 ENST00000361573.2
ENST00000541138.1
ENST00000539601.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr20_-_61733657 0.24 ENST00000608031.1
ENST00000447910.2
HAR1B
highly accelerated region 1B (non-protein coding)
chr17_+_38121772 0.24 ENST00000577447.1
GSDMA
gasdermin A
chr18_-_3247084 0.24 ENST00000609924.1
RP13-270P17.3
RP13-270P17.3
chr20_+_48429233 0.23 ENST00000417961.1
SLC9A8
solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
chr2_+_234600253 0.23 ENST00000373424.1
ENST00000441351.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr14_-_100841794 0.23 ENST00000556295.1
ENST00000554820.1
WARS
tryptophanyl-tRNA synthetase
chr8_-_125869733 0.23 ENST00000533496.1
RP11-1082L8.3
RP11-1082L8.3
chr2_+_119699864 0.23 ENST00000541757.1
ENST00000412481.1
MARCO
macrophage receptor with collagenous structure
chr17_-_3595042 0.23 ENST00000552723.1
P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr10_+_88728189 0.23 ENST00000416348.1
ADIRF
adipogenesis regulatory factor
chr9_+_140149625 0.23 ENST00000343053.4
NELFB
negative elongation factor complex member B
chr19_-_54726850 0.22 ENST00000245620.9
ENST00000346401.6
ENST00000424807.1
ENST00000445347.1
LILRB3
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
chr19_-_8567505 0.22 ENST00000600262.1
PRAM1
PML-RARA regulated adaptor molecule 1
chr2_+_233415363 0.22 ENST00000409514.1
ENST00000409098.1
ENST00000409495.1
ENST00000409167.3
ENST00000409322.1
ENST00000409394.1
EIF4E2
eukaryotic translation initiation factor 4E family member 2
chr7_+_97840739 0.22 ENST00000609256.1
BHLHA15
basic helix-loop-helix family, member a15
chr3_-_128294929 0.22 ENST00000356020.2
C3orf27
chromosome 3 open reading frame 27
chr2_+_131328402 0.21 ENST00000409793.1
ENST00000409982.1
AC140481.2
Uncharacterized protein
chr1_+_26517052 0.21 ENST00000338855.2
ENST00000456354.2
CATSPER4
cation channel, sperm associated 4
chr19_-_45457264 0.21 ENST00000591646.1
CTB-129P6.11
Uncharacterized protein
chr1_+_38273818 0.21 ENST00000373042.4
C1orf122
chromosome 1 open reading frame 122
chr8_-_144674284 0.20 ENST00000528519.1
EEF1D
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr2_+_231090471 0.20 ENST00000373645.3
SP140
SP140 nuclear body protein
chr22_+_46476192 0.20 ENST00000443490.1
FLJ27365
hsa-mir-4763
chr12_+_54378849 0.20 ENST00000515593.1
HOXC10
homeobox C10
chr3_+_169684553 0.20 ENST00000337002.4
ENST00000480708.1
SEC62
SEC62 homolog (S. cerevisiae)
chr20_+_55204351 0.20 ENST00000201031.2
TFAP2C
transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
chr7_-_84569561 0.20 ENST00000439105.1
AC074183.4
AC074183.4
chr13_+_103451548 0.20 ENST00000419638.1
BIVM
basic, immunoglobulin-like variable motif containing
chr10_+_129845670 0.20 ENST00000467366.1
PTPRE
protein tyrosine phosphatase, receptor type, E
chr14_-_75536182 0.20 ENST00000555463.1
ACYP1
acylphosphatase 1, erythrocyte (common) type
chr10_+_4828815 0.20 ENST00000533295.1
AKR1E2
aldo-keto reductase family 1, member E2
chr22_+_30821732 0.20 ENST00000355143.4
MTFP1
mitochondrial fission process 1
chr19_-_18995029 0.20 ENST00000596048.1
CERS1
ceramide synthase 1
chr1_+_1167594 0.19 ENST00000379198.2
B3GALT6
UDP-Gal:betaGal beta 1,3-galactosyltransferase polypeptide 6
chr9_+_129987488 0.19 ENST00000446764.1
GARNL3
GTPase activating Rap/RanGAP domain-like 3
chr3_-_118864861 0.19 ENST00000441144.2
IGSF11
immunoglobulin superfamily, member 11
chr10_-_103535657 0.19 ENST00000344255.3
ENST00000320185.2
ENST00000346714.3
ENST00000347978.2
FGF8
fibroblast growth factor 8 (androgen-induced)
chr9_-_130661916 0.19 ENST00000373142.1
ENST00000373146.1
ENST00000373144.3
ST6GALNAC6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr6_+_31082603 0.19 ENST00000259881.9
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr2_+_113479063 0.19 ENST00000327581.4
NT5DC4
5'-nucleotidase domain containing 4
chr19_+_8740061 0.19 ENST00000593792.1
CTD-2586B10.1
CTD-2586B10.1
chr12_+_100967420 0.19 ENST00000266754.5
ENST00000547754.1
GAS2L3
growth arrest-specific 2 like 3
chr22_+_30821784 0.19 ENST00000407550.3
MTFP1
mitochondrial fission process 1
chr10_-_123687943 0.19 ENST00000540606.1
ENST00000455628.1
ATE1
arginyltransferase 1
chr5_-_180287663 0.19 ENST00000509066.1
ENST00000504225.1
ZFP62
ZFP62 zinc finger protein
chr8_+_75512010 0.19 ENST00000518190.1
ENST00000523118.1
RP11-758M4.1
Uncharacterized protein
chr1_-_24151903 0.19 ENST00000436439.2
ENST00000374490.3
HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr3_+_48488114 0.19 ENST00000421175.1
ENST00000320211.3
ENST00000346691.4
ENST00000357105.6
ATRIP
ATR interacting protein
chrX_-_21776281 0.19 ENST00000379494.3
SMPX
small muscle protein, X-linked
chr4_+_124320665 0.19 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr20_-_62258394 0.19 ENST00000370077.1
GMEB2
glucocorticoid modulatory element binding protein 2
chr19_+_39574945 0.19 ENST00000331256.5
PAPL
Iron/zinc purple acid phosphatase-like protein
chr16_+_1383602 0.19 ENST00000426824.3
ENST00000397488.2
ENST00000562208.1
ENST00000568887.1
BAIAP3
BAI1-associated protein 3
chr9_+_136243117 0.19 ENST00000426926.2
ENST00000371957.3
C9orf96
chromosome 9 open reading frame 96
chr4_-_140201333 0.19 ENST00000398955.1
MGARP
mitochondria-localized glutamic acid-rich protein
chr11_-_86383461 0.19 ENST00000532471.1
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr6_-_105584560 0.19 ENST00000336775.5
BVES
blood vessel epicardial substance
chr6_-_159420780 0.18 ENST00000449822.1
RSPH3
radial spoke 3 homolog (Chlamydomonas)
chr16_-_28621298 0.18 ENST00000566189.1
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr6_+_31021225 0.18 ENST00000565192.1
ENST00000562344.1
HCG22
HLA complex group 22
chr11_-_9482010 0.18 ENST00000596206.1
AC132192.1
LOC644656 protein; Uncharacterized protein
chr14_+_52780998 0.18 ENST00000557436.1
PTGER2
prostaglandin E receptor 2 (subtype EP2), 53kDa
chr1_-_32827682 0.18 ENST00000432622.1
FAM229A
family with sequence similarity 229, member A
chr19_-_51512804 0.18 ENST00000594211.1
ENST00000376832.4
KLK9
kallikrein-related peptidase 9
chr3_-_156534754 0.18 ENST00000472943.1
ENST00000473352.1
LINC00886
long intergenic non-protein coding RNA 886
chr22_-_37505449 0.18 ENST00000406725.1
TMPRSS6
transmembrane protease, serine 6
chr6_+_31021973 0.18 ENST00000570223.1
ENST00000566475.1
ENST00000426185.1
HCG22
HLA complex group 22
chr19_+_18283959 0.18 ENST00000597802.2
IFI30
interferon, gamma-inducible protein 30
chr22_-_37880543 0.18 ENST00000442496.1
MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_-_36916011 0.18 ENST00000356637.5
ENST00000354267.3
ENST00000235532.5
OSCP1
organic solute carrier partner 1
chr1_+_179851893 0.18 ENST00000531630.2
TOR1AIP1
torsin A interacting protein 1
chr10_-_105218645 0.18 ENST00000329905.5
CALHM1
calcium homeostasis modulator 1
chr19_+_12203100 0.17 ENST00000596883.1
ZNF788
zinc finger family member 788
chr14_-_100842588 0.17 ENST00000556645.1
ENST00000556209.1
ENST00000556504.1
ENST00000556435.1
ENST00000554772.1
ENST00000553581.1
ENST00000553769.2
ENST00000554605.1
ENST00000557722.1
ENST00000553413.1
ENST00000553524.1
ENST00000358655.4
WARS
tryptophanyl-tRNA synthetase
chr16_+_77246337 0.17 ENST00000563157.1
SYCE1L
synaptonemal complex central element protein 1-like
chr16_-_30596818 0.17 ENST00000567773.1
ZNF785
zinc finger protein 785
chr16_+_29471210 0.17 ENST00000360423.7
SULT1A4
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4
chr3_-_139396560 0.17 ENST00000514703.1
ENST00000511444.1
NMNAT3
nicotinamide nucleotide adenylyltransferase 3
chr18_+_33552597 0.17 ENST00000269194.6
ENST00000587873.1
C18orf21
chromosome 18 open reading frame 21
chr2_+_74212073 0.17 ENST00000441217.1
AC073046.25
AC073046.25
chr8_-_103136481 0.17 ENST00000524209.1
ENST00000517822.1
ENST00000523923.1
ENST00000521599.1
ENST00000521964.1
ENST00000311028.3
ENST00000518166.1
NCALD
neurocalcin delta
chr19_-_12251202 0.17 ENST00000334213.5
ZNF20
zinc finger protein 20
chr11_-_86383370 0.17 ENST00000526834.1
ENST00000359636.2
ME3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr11_+_60614946 0.17 ENST00000545580.1
CCDC86
coiled-coil domain containing 86
chr12_-_92821922 0.17 ENST00000538965.1
ENST00000378487.2
CLLU1OS
chronic lymphocytic leukemia up-regulated 1 opposite strand
chr10_-_47181681 0.17 ENST00000452267.1
FAM25B
family with sequence similarity 25, member B
chr4_-_89080362 0.16 ENST00000503830.1
ABCG2
ATP-binding cassette, sub-family G (WHITE), member 2
chr16_-_28621312 0.16 ENST00000314752.7
SULT1A1
sulfotransferase family, cytosolic, 1A, phenol-preferring, member 1
chr8_-_144890847 0.16 ENST00000531942.1
SCRIB
scribbled planar cell polarity protein
chr19_-_22806764 0.16 ENST00000598042.1
AC011516.2
AC011516.2
chr10_+_48247669 0.16 ENST00000457620.1
FAM25G
family with sequence similarity 25, member G
chr16_+_616995 0.16 ENST00000293874.2
ENST00000409527.2
ENST00000424439.2
ENST00000540585.1
PIGQ
NHLRC4
phosphatidylinositol glycan anchor biosynthesis, class Q
NHL repeat containing 4
chr14_-_91720224 0.16 ENST00000238699.3
ENST00000531499.2
GPR68
G protein-coupled receptor 68
chr22_-_36031181 0.16 ENST00000594060.1
AL049747.1
AL049747.1
chr6_-_112115103 0.16 ENST00000462598.3
FYN
FYN oncogene related to SRC, FGR, YES
chr11_+_8704298 0.16 ENST00000531978.1
ENST00000524496.1
ENST00000532359.1
ENST00000530022.1
RPL27A
ribosomal protein L27a
chr2_+_119981384 0.16 ENST00000393108.2
ENST00000354888.5
ENST00000450943.2
ENST00000393110.2
ENST00000393106.2
ENST00000409811.1
ENST00000393107.2
STEAP3
STEAP family member 3, metalloreductase
chr15_-_66649010 0.16 ENST00000367709.4
ENST00000261881.4
TIPIN
TIMELESS interacting protein
chr17_-_34207295 0.16 ENST00000463941.1
ENST00000293272.3
CCL5
chemokine (C-C motif) ligand 5
chr8_-_101571964 0.16 ENST00000520552.1
ENST00000521345.1
ENST00000523000.1
ENST00000335659.3
ENST00000358990.3
ENST00000519597.1
ANKRD46
ankyrin repeat domain 46
chr22_+_42470289 0.16 ENST00000419475.1
FAM109B
family with sequence similarity 109, member B
chr15_+_42696992 0.16 ENST00000561817.1
CAPN3
calpain 3, (p94)
chr3_-_52488048 0.16 ENST00000232975.3
TNNC1
troponin C type 1 (slow)
chr1_-_24151892 0.16 ENST00000235958.4
HMGCL
3-hydroxymethyl-3-methylglutaryl-CoA lyase
chr1_-_38218577 0.16 ENST00000540011.1
EPHA10
EPH receptor A10
chr2_+_119699742 0.16 ENST00000327097.4
MARCO
macrophage receptor with collagenous structure
chr17_-_79869340 0.16 ENST00000538936.2
PCYT2
phosphate cytidylyltransferase 2, ethanolamine
chr19_-_2739992 0.16 ENST00000545664.1
ENST00000589363.1
ENST00000455372.2
SLC39A3
solute carrier family 39 (zinc transporter), member 3
chr1_+_154401791 0.15 ENST00000476006.1
IL6R
interleukin 6 receptor
chr15_+_83209620 0.15 ENST00000568285.1
RP11-379H8.1
Uncharacterized protein
chr12_-_104359475 0.15 ENST00000553183.1
C12orf73
chromosome 12 open reading frame 73
chr19_+_1491144 0.15 ENST00000233596.3
REEP6
receptor accessory protein 6
chr18_+_33552667 0.15 ENST00000333234.5
C18orf21
chromosome 18 open reading frame 21
chr12_-_42877726 0.15 ENST00000548696.1
PRICKLE1
prickle homolog 1 (Drosophila)
chr20_+_39765581 0.15 ENST00000244007.3
PLCG1
phospholipase C, gamma 1
chr15_+_101389945 0.15 ENST00000561231.1
ENST00000559331.1
ENST00000558254.1
RP11-66B24.2
RP11-66B24.2
chr2_+_151485403 0.15 ENST00000413247.1
ENST00000423428.1
ENST00000427615.1
ENST00000443811.1
AC104777.4
AC104777.4
chr20_+_44098385 0.15 ENST00000217425.5
ENST00000339946.3
WFDC2
WAP four-disulfide core domain 2
chr3_+_139062838 0.15 ENST00000310776.4
ENST00000465056.1
ENST00000465373.1
MRPS22
mitochondrial ribosomal protein S22
chr6_+_42984723 0.15 ENST00000332245.8
KLHDC3
kelch domain containing 3
chr17_-_4806369 0.15 ENST00000293780.4
CHRNE
cholinergic receptor, nicotinic, epsilon (muscle)
chr19_-_13213662 0.15 ENST00000264824.4
LYL1
lymphoblastic leukemia derived sequence 1
chr15_-_64338521 0.15 ENST00000457488.1
ENST00000558069.1
DAPK2
death-associated protein kinase 2
chr16_+_31225337 0.15 ENST00000322122.3
TRIM72
tripartite motif containing 72
chr11_+_69924679 0.15 ENST00000531604.1
ANO1
anoctamin 1, calcium activated chloride channel
chr5_+_149109825 0.15 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B
peroxisome proliferator-activated receptor gamma, coactivator 1 beta
chr19_-_58864848 0.15 ENST00000263100.3
A1BG
alpha-1-B glycoprotein
chr19_-_8567478 0.15 ENST00000255612.3
PRAM1
PML-RARA regulated adaptor molecule 1
chr1_-_223853348 0.15 ENST00000366872.5
CAPN8
calpain 8
chr17_+_80818231 0.15 ENST00000576996.1
TBCD
tubulin folding cofactor D
chr20_-_44519839 0.15 ENST00000372518.4
NEURL2
neuralized E3 ubiquitin protein ligase 2
chr1_+_245133656 0.15 ENST00000366521.3
EFCAB2
EF-hand calcium binding domain 2
chr6_-_91006461 0.14 ENST00000257749.4
ENST00000343122.3
ENST00000406998.2
ENST00000453877.1
BACH2
BTB and CNC homology 1, basic leucine zipper transcription factor 2
chr3_-_118864893 0.14 ENST00000354673.2
ENST00000425327.2
IGSF11
immunoglobulin superfamily, member 11
chr20_+_1246908 0.14 ENST00000381873.3
ENST00000381867.1
SNPH
syntaphilin
chr11_-_62439012 0.14 ENST00000532208.1
ENST00000377954.2
ENST00000415855.2
ENST00000431002.2
ENST00000354588.3
C11orf48
chromosome 11 open reading frame 48
chr5_-_131630931 0.14 ENST00000431054.1
P4HA2
prolyl 4-hydroxylase, alpha polypeptide II
chr11_-_1036706 0.14 ENST00000421673.2
MUC6
mucin 6, oligomeric mucus/gel-forming
chr12_+_123259063 0.14 ENST00000392441.4
ENST00000539171.1
CCDC62
coiled-coil domain containing 62
chr19_-_36001386 0.14 ENST00000461300.1
DMKN
dermokine
chr6_-_109776901 0.14 ENST00000431946.1
MICAL1
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr1_-_917466 0.14 ENST00000341290.2
C1orf170
chromosome 1 open reading frame 170
chr20_-_45280091 0.14 ENST00000396360.1
ENST00000435032.1
ENST00000413164.2
ENST00000372121.1
ENST00000339636.3
SLC13A3
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
chr5_+_32710736 0.14 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr16_-_74455290 0.14 ENST00000339953.5
CLEC18B
C-type lectin domain family 18, member B
chr12_+_7072354 0.14 ENST00000537269.1
U47924.27
U47924.27
chr4_-_668108 0.14 ENST00000304312.4
ATP5I
ATP synthase, H+ transporting, mitochondrial Fo complex, subunit E
chr14_+_102606181 0.14 ENST00000335263.5
ENST00000322340.5
ENST00000424963.2
ENST00000342702.3
ENST00000556807.1
ENST00000499851.2
ENST00000558567.1
ENST00000299135.6
ENST00000454394.2
ENST00000556511.2
WDR20
WD repeat domain 20
chr9_-_134151915 0.14 ENST00000372271.3
FAM78A
family with sequence similarity 78, member A
chr14_+_52456327 0.14 ENST00000556760.1
C14orf166
chromosome 14 open reading frame 166
chr19_+_571277 0.14 ENST00000346916.4
ENST00000545507.2
BSG
basigin (Ok blood group)
chr11_+_33563618 0.14 ENST00000526400.1
KIAA1549L
KIAA1549-like
chr17_-_1508379 0.14 ENST00000412517.3
SLC43A2
solute carrier family 43 (amino acid system L transporter), member 2
chr22_-_50708781 0.14 ENST00000449719.2
ENST00000330651.6
MAPK11
mitogen-activated protein kinase 11
chr2_-_233415220 0.14 ENST00000408957.3
TIGD1
tigger transposable element derived 1
chr19_+_42829702 0.14 ENST00000334370.4
MEGF8
multiple EGF-like-domains 8

Network of associatons between targets according to the STRING database.

First level regulatory network of ESR1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.5 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.3 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1 0.2 GO:0072720 cellular response to mycotoxin(GO:0036146) response to dithiothreitol(GO:0072720)
0.1 0.2 GO:0060129 thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.2 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.1 GO:0061138 branching morphogenesis of an epithelial tube(GO:0048754) morphogenesis of a branching epithelium(GO:0061138)
0.1 0.1 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 0.2 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.1 0.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.2 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.5 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.2 GO:0051389 inactivation of MAPKK activity(GO:0051389)
0.1 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390) transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0038178 complement component C5a signaling pathway(GO:0038178) negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024) negative regulation of neutrophil migration(GO:1902623)
0.0 0.1 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.0 0.2 GO:0016598 protein arginylation(GO:0016598)
0.0 0.2 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.6 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.3 GO:0015744 tricarboxylic acid transport(GO:0006842) succinate transport(GO:0015744) citrate transport(GO:0015746) succinate transmembrane transport(GO:0071422)
0.0 0.2 GO:0009386 translational attenuation(GO:0009386)
0.0 0.1 GO:1903625 negative regulation of sperm motility(GO:1901318) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.1 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.0 0.3 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.2 GO:0032972 regulation of muscle filament sliding speed(GO:0032972)
0.0 0.1 GO:0007387 anterior compartment pattern formation(GO:0007387) posterior compartment specification(GO:0007388)
0.0 0.2 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:0097198 histone H3-K36 trimethylation(GO:0097198)
0.0 0.2 GO:0097210 response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.3 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.1 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.0 0.1 GO:0060931 sinoatrial node development(GO:0003163) sinoatrial node cell differentiation(GO:0060921) sinoatrial node cell development(GO:0060931)
0.0 0.2 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.3 GO:0006552 leucine catabolic process(GO:0006552)
0.0 0.1 GO:0071879 UDP-glucose catabolic process(GO:0006258) positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:0033319 UDP-D-xylose metabolic process(GO:0033319) UDP-D-xylose biosynthetic process(GO:0033320)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 1.0 GO:0009812 flavonoid metabolic process(GO:0009812)
0.0 0.1 GO:0032242 regulation of nucleoside transport(GO:0032242)
0.0 0.1 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.0 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.3 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.2 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.2 GO:2001023 regulation of response to drug(GO:2001023)
0.0 0.1 GO:1902559 3'-phosphoadenosine 5'-phosphosulfate transport(GO:0046963) 3'-phospho-5'-adenylyl sulfate transmembrane transport(GO:1902559)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.1 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.2 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693) semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.1 GO:1902824 cleavage furrow ingression(GO:0036090) positive regulation of late endosome to lysosome transport(GO:1902824)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.2 GO:0014718 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) molecular hydrogen transport(GO:0015993) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0051891 positive regulation of cardioblast differentiation(GO:0051891)
0.0 0.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.4 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.0 0.1 GO:0019521 aldonic acid metabolic process(GO:0019520) D-gluconate metabolic process(GO:0019521)
0.0 0.1 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.1 GO:2000307 iron assimilation(GO:0033212) iron assimilation by chelation and transport(GO:0033214) tumor necrosis factor (ligand) superfamily member 11 production(GO:0072535) regulation of bone mineralization involved in bone maturation(GO:1900157) positive regulation of bone mineralization involved in bone maturation(GO:1900159) regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000307) negative regulation of tumor necrosis factor (ligand) superfamily member 11 production(GO:2000308)
0.0 0.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.2 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0072287 metanephric distal tubule morphogenesis(GO:0072287)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.2 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.1 GO:0021539 subthalamus development(GO:0021539)
0.0 0.1 GO:0002432 granuloma formation(GO:0002432)
0.0 0.5 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035) 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.1 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.4 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.1 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.0 0.2 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.2 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.0 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.0 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.2 GO:1903416 regulation of resting membrane potential(GO:0060075) response to glycoside(GO:1903416)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:0098734 macromolecule depalmitoylation(GO:0098734)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.0 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:0016559 peroxisome fission(GO:0016559)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.1 GO:0015788 GDP-fucose transport(GO:0015783) UDP-N-acetylglucosamine transport(GO:0015788) purine nucleotide-sugar transport(GO:0036079) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.5 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.1 GO:0045780 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.0 GO:0033037 polysaccharide localization(GO:0033037)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0046689 response to mercury ion(GO:0046689)
0.0 0.0 GO:0035854 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.0 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.0 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0015855 pyrimidine nucleobase transport(GO:0015855) purine nucleobase transmembrane transport(GO:1904823)
0.0 0.6 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.0 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.0 0.0 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.0 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0071392 cellular response to estradiol stimulus(GO:0071392)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.4 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.2 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.0 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.3 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.2 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.2 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.0 0.1 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.0 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.2 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0002133 polycystin complex(GO:0002133)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0097013 phagocytic vesicle lumen(GO:0097013)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0047894 flavonol 3-sulfotransferase activity(GO:0047894)
0.1 0.5 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.3 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.3 GO:0004419 hydroxymethylglutaryl-CoA lyase activity(GO:0004419)
0.1 0.2 GO:0050571 1,5-anhydro-D-fructose reductase activity(GO:0050571)
0.1 0.5 GO:0004471 malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
0.1 0.2 GO:0004961 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.1 0.3 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.1 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1 0.2 GO:0070119 ciliary neurotrophic factor binding(GO:0070119)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0004057 arginyltransferase activity(GO:0004057)
0.0 0.1 GO:0090541 MIT domain binding(GO:0090541)
0.0 0.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.3 GO:0017153 citrate transmembrane transporter activity(GO:0015137) succinate transmembrane transporter activity(GO:0015141) tricarboxylic acid transmembrane transporter activity(GO:0015142) sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.2 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0048040 UDP-glucuronate decarboxylase activity(GO:0048040)
0.0 0.1 GO:0050698 proteoglycan sulfotransferase activity(GO:0050698)
0.0 0.2 GO:0004306 ethanolamine-phosphate cytidylyltransferase activity(GO:0004306)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.2 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.1 GO:0031896 vasopressin receptor binding(GO:0031893) V2 vasopressin receptor binding(GO:0031896)
0.0 0.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.0 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0 0.1 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.0 0.7 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.2 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0005010 insulin-like growth factor-activated receptor activity(GO:0005010)
0.0 0.8 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0050682 AF-2 domain binding(GO:0050682)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.2 GO:0004308 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.0 0.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.2 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.4 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.2 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0005462 GDP-fucose transmembrane transporter activity(GO:0005457) UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.0 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.2 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.4 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.0 GO:0004139 deoxyribose-phosphate aldolase activity(GO:0004139)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 1.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.0 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.5 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 1.0 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport