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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EP300

Z-value: 0.67

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Transcription factors associated with EP300

Gene Symbol Gene ID Gene Info
EP300
ENSG00000100393.9 E1A binding protein p300

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EP300hg19_v2_chr22_+_41487711_41487798-0.621.9e-01Click!

Activity profile of EP300 motif

Sorted Z-values of EP300 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_102188272 0.60 ENST00000532808.1
BIRC3
baculoviral IAP repeat containing 3
chr11_+_102188224 0.56 ENST00000263464.3
BIRC3
baculoviral IAP repeat containing 3
chr12_+_72058130 0.55 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr6_-_30685214 0.44 ENST00000425072.1
MDC1
mediator of DNA-damage checkpoint 1
chr10_+_81892477 0.35 ENST00000372263.3
PLAC9
placenta-specific 9
chr17_-_14140166 0.32 ENST00000420162.2
ENST00000431716.2
CDRT15
CMT1A duplicated region transcript 15
chr4_-_74853897 0.30 ENST00000296028.3
PPBP
pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)
chr18_+_5238549 0.27 ENST00000580684.1
LINC00667
long intergenic non-protein coding RNA 667
chr11_-_114271139 0.27 ENST00000325636.4
C11orf71
chromosome 11 open reading frame 71
chr12_-_122241812 0.26 ENST00000538335.1
AC084018.1
AC084018.1
chr19_-_1174226 0.25 ENST00000587024.1
ENST00000361757.3
SBNO2
strawberry notch homolog 2 (Drosophila)
chr1_+_206643806 0.24 ENST00000537984.1
IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr19_+_49617581 0.23 ENST00000391864.3
LIN7B
lin-7 homolog B (C. elegans)
chr1_-_157108266 0.23 ENST00000326786.4
ETV3
ets variant 3
chr1_+_206643787 0.22 ENST00000367120.3
IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr15_-_74726283 0.22 ENST00000543145.2
SEMA7A
semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
chr10_+_102729249 0.21 ENST00000519649.1
ENST00000518124.1
SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr3_-_130745403 0.20 ENST00000504725.1
ENST00000509060.1
ASTE1
asteroid homolog 1 (Drosophila)
chr14_-_69445793 0.19 ENST00000538545.2
ENST00000394419.4
ACTN1
actinin, alpha 1
chr6_-_30684898 0.19 ENST00000422266.1
ENST00000416571.1
MDC1
mediator of DNA-damage checkpoint 1
chr20_+_19738792 0.18 ENST00000412571.1
RP1-122P22.2
RP1-122P22.2
chr1_-_209957882 0.18 ENST00000294811.1
C1orf74
chromosome 1 open reading frame 74
chr16_+_69373471 0.18 ENST00000569637.2
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr6_+_126240442 0.18 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr16_+_69373323 0.17 ENST00000254940.5
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr8_-_33424636 0.17 ENST00000256257.1
RNF122
ring finger protein 122
chr5_+_443280 0.17 ENST00000508022.1
EXOC3
exocyst complex component 3
chr20_+_58630972 0.17 ENST00000313426.1
C20orf197
chromosome 20 open reading frame 197
chr11_-_57194550 0.17 ENST00000528187.1
ENST00000524863.1
ENST00000533051.1
ENST00000529494.1
ENST00000395124.1
ENST00000533524.1
ENST00000533245.1
ENST00000530316.1
SLC43A3
solute carrier family 43, member 3
chr14_-_69445968 0.16 ENST00000438964.2
ACTN1
actinin, alpha 1
chr10_+_105127704 0.16 ENST00000369839.3
ENST00000351396.4
TAF5
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
chr11_-_57194418 0.16 ENST00000395123.2
ENST00000530005.1
ENST00000532278.1
SLC43A3
solute carrier family 43, member 3
chr17_+_7255208 0.16 ENST00000333751.3
KCTD11
potassium channel tetramerization domain containing 11
chr1_+_11866270 0.15 ENST00000376497.3
ENST00000376487.3
ENST00000376496.3
CLCN6
chloride channel, voltage-sensitive 6
chr5_+_130506629 0.15 ENST00000510516.1
ENST00000507584.1
LYRM7
LYR motif containing 7
chr7_-_139756791 0.15 ENST00000489809.1
PARP12
poly (ADP-ribose) polymerase family, member 12
chr12_-_49525175 0.14 ENST00000336023.5
ENST00000550367.1
ENST00000552984.1
ENST00000547476.1
TUBA1B
tubulin, alpha 1b
chr19_-_6110457 0.14 ENST00000586302.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr3_+_171758344 0.14 ENST00000336824.4
ENST00000423424.1
FNDC3B
fibronectin type III domain containing 3B
chr14_-_24711865 0.14 ENST00000399423.4
ENST00000267415.7
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr7_-_944631 0.14 ENST00000453175.2
ADAP1
ArfGAP with dual PH domains 1
chr10_+_30723533 0.14 ENST00000413724.1
MAP3K8
mitogen-activated protein kinase kinase kinase 8
chr2_+_232573208 0.14 ENST00000409115.3
PTMA
prothymosin, alpha
chr1_+_20915409 0.13 ENST00000375071.3
CDA
cytidine deaminase
chr1_+_11866207 0.13 ENST00000312413.6
ENST00000346436.6
CLCN6
chloride channel, voltage-sensitive 6
chr14_-_38064198 0.13 ENST00000250448.2
FOXA1
forkhead box A1
chr14_+_77582905 0.13 ENST00000557408.1
TMEM63C
transmembrane protein 63C
chr17_-_19265855 0.13 ENST00000440841.1
ENST00000395615.1
ENST00000461069.2
B9D1
B9 protein domain 1
chr1_-_95007193 0.13 ENST00000370207.4
ENST00000334047.7
F3
coagulation factor III (thromboplastin, tissue factor)
chr11_+_129685707 0.13 ENST00000281441.3
TMEM45B
transmembrane protein 45B
chr1_+_38478432 0.12 ENST00000537711.1
UTP11L
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr13_-_36871886 0.12 ENST00000491049.2
ENST00000503173.1
ENST00000239860.6
ENST00000379862.2
ENST00000239859.7
ENST00000379864.2
ENST00000510088.1
ENST00000554962.1
ENST00000511166.1
CCDC169
SOHLH2
CCDC169-SOHLH2
coiled-coil domain containing 169
spermatogenesis and oogenesis specific basic helix-loop-helix 2
CCDC169-SOHLH2 readthrough
chr1_-_40237020 0.12 ENST00000327582.5
OXCT2
3-oxoacid CoA transferase 2
chr9_-_133814455 0.12 ENST00000448616.1
FIBCD1
fibrinogen C domain containing 1
chr6_-_149969829 0.12 ENST00000367411.2
KATNA1
katanin p60 (ATPase containing) subunit A 1
chr17_-_19265982 0.12 ENST00000268841.6
ENST00000261499.4
ENST00000575478.1
B9D1
B9 protein domain 1
chr14_-_69446034 0.12 ENST00000193403.6
ACTN1
actinin, alpha 1
chr3_-_158450475 0.12 ENST00000237696.5
RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr14_-_24711470 0.12 ENST00000559969.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr22_+_46731596 0.12 ENST00000381019.3
TRMU
tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
chr1_-_1590418 0.12 ENST00000341028.7
CDK11B
cyclin-dependent kinase 11B
chr12_+_52463751 0.12 ENST00000336854.4
ENST00000550604.1
ENST00000553049.1
ENST00000548915.1
C12orf44
chromosome 12 open reading frame 44
chrX_+_23685653 0.12 ENST00000379331.3
PRDX4
peroxiredoxin 4
chr1_+_38478378 0.11 ENST00000373014.4
UTP11L
UTP11-like, U3 small nucleolar ribonucleoprotein, (yeast)
chr3_+_19988736 0.11 ENST00000443878.1
RAB5A
RAB5A, member RAS oncogene family
chr1_-_54518865 0.11 ENST00000371337.3
TMEM59
transmembrane protein 59
chr14_-_24711806 0.11 ENST00000540705.1
ENST00000538777.1
ENST00000558566.1
ENST00000559019.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr6_+_43738444 0.11 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA
vascular endothelial growth factor A
chr4_+_56814968 0.11 ENST00000422247.2
CEP135
centrosomal protein 135kDa
chr7_+_90032821 0.11 ENST00000427904.1
CLDN12
claudin 12
chr20_-_30311703 0.11 ENST00000450273.1
ENST00000456404.1
ENST00000420488.1
ENST00000439267.1
BCL2L1
BCL2-like 1
chr14_-_24711764 0.11 ENST00000557921.1
ENST00000558476.1
TINF2
TERF1 (TRF1)-interacting nuclear factor 2
chr1_+_157963391 0.11 ENST00000359209.6
ENST00000416935.2
KIRREL
kin of IRRE like (Drosophila)
chr7_-_5569588 0.11 ENST00000417101.1
ACTB
actin, beta
chr1_+_3541543 0.11 ENST00000378344.2
ENST00000344579.5
TPRG1L
tumor protein p63 regulated 1-like
chr2_+_232573222 0.11 ENST00000341369.7
ENST00000409683.1
PTMA
prothymosin, alpha
chr12_-_124118151 0.11 ENST00000534960.1
EIF2B1
eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa
chr5_+_89770696 0.10 ENST00000504930.1
ENST00000514483.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr1_-_155658260 0.10 ENST00000368339.5
ENST00000405763.3
ENST00000368340.5
ENST00000454523.1
ENST00000443231.1
ENST00000347088.5
ENST00000361831.5
ENST00000355499.4
YY1AP1
YY1 associated protein 1
chr1_+_155657737 0.10 ENST00000471642.2
ENST00000471214.1
DAP3
death associated protein 3
chr11_+_126081662 0.10 ENST00000528985.1
ENST00000529731.1
ENST00000360194.4
ENST00000530043.1
FAM118B
family with sequence similarity 118, member B
chr16_-_66968055 0.10 ENST00000568572.1
FAM96B
family with sequence similarity 96, member B
chr21_+_30671189 0.10 ENST00000286800.3
BACH1
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr17_+_21188012 0.10 ENST00000529517.1
MAP2K3
mitogen-activated protein kinase kinase 3
chr15_-_90437195 0.10 ENST00000560940.1
ENST00000558011.1
AP3S2
adaptor-related protein complex 3, sigma 2 subunit
chr20_+_44035200 0.10 ENST00000372717.1
ENST00000360981.4
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr20_+_55926625 0.10 ENST00000452119.1
RAE1
ribonucleic acid export 1
chr10_-_126849626 0.09 ENST00000530884.1
CTBP2
C-terminal binding protein 2
chr19_+_10217270 0.09 ENST00000446223.1
PPAN
peter pan homolog (Drosophila)
chr8_-_11325047 0.09 ENST00000531804.1
FAM167A
family with sequence similarity 167, member A
chr9_-_133814527 0.09 ENST00000451466.1
FIBCD1
fibrinogen C domain containing 1
chr15_+_38544476 0.09 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr16_+_66400533 0.09 ENST00000341529.3
CDH5
cadherin 5, type 2 (vascular endothelium)
chr19_+_1000418 0.09 ENST00000234389.3
GRIN3B
glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
chr3_-_79816965 0.09 ENST00000464233.1
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr5_-_39425068 0.09 ENST00000515700.1
ENST00000339788.6
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr5_-_1344999 0.09 ENST00000320927.6
CLPTM1L
CLPTM1-like
chr2_+_25016282 0.09 ENST00000260662.1
CENPO
centromere protein O
chr8_+_144816303 0.09 ENST00000533004.1
FAM83H-AS1
FAM83H antisense RNA 1 (head to head)
chr4_+_75311019 0.09 ENST00000502307.1
AREG
amphiregulin
chr22_-_29137771 0.09 ENST00000439200.1
ENST00000405598.1
ENST00000398017.2
ENST00000425190.2
ENST00000348295.3
ENST00000382578.1
ENST00000382565.1
ENST00000382566.1
ENST00000382580.2
ENST00000328354.6
CHEK2
checkpoint kinase 2
chr11_-_123612319 0.09 ENST00000526252.1
ENST00000530393.1
ENST00000533463.1
ENST00000336139.4
ENST00000529691.1
ENST00000528306.1
ZNF202
zinc finger protein 202
chr18_+_33709834 0.09 ENST00000358232.6
ENST00000351393.6
ENST00000442325.2
ENST00000423854.2
ENST00000350494.6
ENST00000542824.1
ELP2
elongator acetyltransferase complex subunit 2
chr2_+_217277466 0.08 ENST00000358207.5
ENST00000434435.1
SMARCAL1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr2_-_70417827 0.08 ENST00000457952.1
C2orf42
chromosome 2 open reading frame 42
chr10_-_99161033 0.08 ENST00000315563.6
ENST00000370992.4
ENST00000414986.1
RRP12
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr17_+_21187976 0.08 ENST00000342679.4
MAP2K3
mitogen-activated protein kinase kinase 3
chr1_-_8938736 0.08 ENST00000234590.4
ENO1
enolase 1, (alpha)
chr1_-_43833628 0.08 ENST00000413844.2
ENST00000372458.3
ELOVL1
ELOVL fatty acid elongase 1
chr14_+_23564700 0.08 ENST00000554203.1
C14orf119
chromosome 14 open reading frame 119
chr10_-_69834973 0.08 ENST00000395187.2
HERC4
HECT and RLD domain containing E3 ubiquitin protein ligase 4
chr15_-_90233907 0.08 ENST00000561224.1
PEX11A
peroxisomal biogenesis factor 11 alpha
chr5_+_89770664 0.08 ENST00000503973.1
ENST00000399107.1
POLR3G
polymerase (RNA) III (DNA directed) polypeptide G (32kD)
chr6_-_33290580 0.08 ENST00000446511.1
ENST00000446403.1
ENST00000414083.2
ENST00000266000.6
ENST00000374542.5
DAXX
death-domain associated protein
chr2_+_192110199 0.08 ENST00000304164.4
MYO1B
myosin IB
chr6_-_107436473 0.08 ENST00000369042.1
BEND3
BEN domain containing 3
chr11_-_63258601 0.08 ENST00000540857.1
ENST00000539221.1
ENST00000301790.4
HRASLS5
HRAS-like suppressor family, member 5
chr3_-_130745571 0.08 ENST00000514044.1
ENST00000264992.3
ASTE1
asteroid homolog 1 (Drosophila)
chr15_+_74908228 0.08 ENST00000566126.1
CLK3
CDC-like kinase 3
chr19_+_10216899 0.08 ENST00000428358.1
ENST00000393796.4
ENST00000253107.7
ENST00000556468.1
ENST00000393793.1
PPAN-P2RY11
PPAN
PPAN-P2RY11 readthrough
peter pan homolog (Drosophila)
chr12_+_21590549 0.08 ENST00000545178.1
ENST00000240651.9
PYROXD1
pyridine nucleotide-disulphide oxidoreductase domain 1
chr16_+_50775948 0.08 ENST00000569681.1
ENST00000569418.1
ENST00000540145.1
CYLD
cylindromatosis (turban tumor syndrome)
chr12_-_48213568 0.08 ENST00000080059.7
ENST00000354334.3
ENST00000430670.1
ENST00000552960.1
ENST00000440293.1
HDAC7
histone deacetylase 7
chr1_-_11865982 0.08 ENST00000418034.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chrX_-_140271249 0.07 ENST00000370526.2
LDOC1
leucine zipper, down-regulated in cancer 1
chr10_-_16859361 0.07 ENST00000377921.3
RSU1
Ras suppressor protein 1
chr12_+_58148842 0.07 ENST00000266643.5
MARCH9
membrane-associated ring finger (C3HC4) 9
chrX_+_55478538 0.07 ENST00000342972.1
MAGEH1
melanoma antigen family H, 1
chr13_-_114567034 0.07 ENST00000327773.6
ENST00000357389.3
GAS6
growth arrest-specific 6
chr17_+_41561317 0.07 ENST00000540306.1
ENST00000262415.3
ENST00000605777.1
DHX8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr5_-_892648 0.07 ENST00000483173.1
ENST00000435709.2
BRD9
bromodomain containing 9
chr1_+_35225339 0.07 ENST00000339480.1
GJB4
gap junction protein, beta 4, 30.3kDa
chr10_-_16859442 0.07 ENST00000602389.1
ENST00000345264.5
RSU1
Ras suppressor protein 1
chr19_+_50084561 0.07 ENST00000246794.5
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chr17_-_76274572 0.07 ENST00000374945.1
RP11-219G17.4
RP11-219G17.4
chr20_+_35201993 0.07 ENST00000373872.4
TGIF2
TGFB-induced factor homeobox 2
chr19_-_10530784 0.07 ENST00000593124.1
CDC37
cell division cycle 37
chr6_+_3000057 0.07 ENST00000397717.2
NQO2
NAD(P)H dehydrogenase, quinone 2
chr16_+_28889703 0.07 ENST00000357084.3
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr3_+_71803201 0.07 ENST00000304411.2
GPR27
G protein-coupled receptor 27
chr10_-_69835001 0.07 ENST00000513996.1
ENST00000412272.2
ENST00000395198.3
ENST00000492996.2
HERC4
HECT and RLD domain containing E3 ubiquitin protein ligase 4
chr16_-_66968265 0.07 ENST00000567511.1
ENST00000422424.2
FAM96B
family with sequence similarity 96, member B
chr4_+_75310851 0.07 ENST00000395748.3
ENST00000264487.2
AREG
amphiregulin
chr1_-_43855444 0.07 ENST00000372455.4
MED8
mediator complex subunit 8
chr19_-_6110474 0.07 ENST00000587181.1
ENST00000587321.1
ENST00000586806.1
ENST00000589742.1
ENST00000592546.1
ENST00000303657.5
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr2_+_192109911 0.07 ENST00000418908.1
ENST00000339514.4
ENST00000392318.3
MYO1B
myosin IB
chr1_+_10003486 0.07 ENST00000403197.1
ENST00000377205.1
NMNAT1
nicotinamide nucleotide adenylyltransferase 1
chr17_+_4843679 0.07 ENST00000576229.1
RNF167
ring finger protein 167
chr2_+_113816685 0.07 ENST00000393200.2
IL36RN
interleukin 36 receptor antagonist
chr19_-_6110555 0.07 ENST00000593241.1
RFX2
regulatory factor X, 2 (influences HLA class II expression)
chr6_-_86352642 0.07 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr1_-_155658518 0.07 ENST00000404643.1
ENST00000359205.5
ENST00000407221.1
YY1AP1
YY1 associated protein 1
chr17_-_19266045 0.07 ENST00000395616.3
B9D1
B9 protein domain 1
chr5_-_1345199 0.07 ENST00000320895.5
CLPTM1L
CLPTM1-like
chr11_+_131781290 0.07 ENST00000425719.2
ENST00000374784.1
NTM
neurotrimin
chr6_+_122793058 0.07 ENST00000392491.2
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr14_+_52327109 0.07 ENST00000335281.4
GNG2
guanine nucleotide binding protein (G protein), gamma 2
chr4_-_187647773 0.07 ENST00000509647.1
FAT1
FAT atypical cadherin 1
chr19_+_47759716 0.07 ENST00000221922.6
CCDC9
coiled-coil domain containing 9
chr10_+_114710211 0.06 ENST00000349937.2
ENST00000369397.4
TCF7L2
transcription factor 7-like 2 (T-cell specific, HMG-box)
chr4_+_75480629 0.06 ENST00000380846.3
AREGB
amphiregulin B
chr19_-_55658281 0.06 ENST00000585321.2
ENST00000587465.2
TNNT1
troponin T type 1 (skeletal, slow)
chr3_+_57741957 0.06 ENST00000295951.3
SLMAP
sarcolemma associated protein
chr1_-_202776392 0.06 ENST00000235790.4
KDM5B
lysine (K)-specific demethylase 5B
chr16_+_69373661 0.06 ENST00000254941.6
NIP7
NIP7, nucleolar pre-rRNA processing protein
chr19_-_55658687 0.06 ENST00000593046.1
TNNT1
troponin T type 1 (skeletal, slow)
chr4_+_2470664 0.06 ENST00000314289.8
ENST00000541204.1
ENST00000502316.1
ENST00000507247.1
ENST00000509258.1
ENST00000511859.1
RNF4
ring finger protein 4
chr19_+_51226648 0.06 ENST00000599973.1
CLEC11A
C-type lectin domain family 11, member A
chr12_-_51611477 0.06 ENST00000389243.4
POU6F1
POU class 6 homeobox 1
chr5_+_65892174 0.06 ENST00000404260.3
ENST00000403625.2
ENST00000406374.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr12_+_53693466 0.06 ENST00000267103.5
ENST00000548632.1
C12orf10
chromosome 12 open reading frame 10
chr2_+_24346324 0.06 ENST00000407625.1
ENST00000420135.2
FAM228B
family with sequence similarity 228, member B
chr20_-_33735070 0.06 ENST00000374491.3
ENST00000542871.1
ENST00000374492.3
EDEM2
ER degradation enhancer, mannosidase alpha-like 2
chr20_+_10199468 0.06 ENST00000254976.2
ENST00000304886.2
SNAP25
synaptosomal-associated protein, 25kDa
chr7_+_48128854 0.06 ENST00000436673.1
ENST00000429491.2
UPP1
uridine phosphorylase 1
chr11_+_236540 0.06 ENST00000532097.1
PSMD13
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr22_-_50963976 0.06 ENST00000252785.3
ENST00000395693.3
SCO2
SCO2 cytochrome c oxidase assembly protein
chr15_-_43663214 0.06 ENST00000561661.1
ZSCAN29
zinc finger and SCAN domain containing 29
chr16_+_2732476 0.06 ENST00000301738.4
ENST00000564195.1
KCTD5
potassium channel tetramerization domain containing 5
chr14_+_56584414 0.06 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr20_+_43104508 0.06 ENST00000262605.4
ENST00000372904.3
TTPAL
tocopherol (alpha) transfer protein-like
chr4_-_54518619 0.06 ENST00000507168.1
ENST00000510143.1
LNX1
ligand of numb-protein X 1, E3 ubiquitin protein ligase
chr16_+_50775971 0.06 ENST00000311559.9
ENST00000564326.1
ENST00000566206.1
CYLD
cylindromatosis (turban tumor syndrome)
chr2_+_191513789 0.06 ENST00000409581.1
NAB1
NGFI-A binding protein 1 (EGR1 binding protein 1)
chr10_+_91461413 0.06 ENST00000447580.1
KIF20B
kinesin family member 20B
chr19_-_44809121 0.06 ENST00000591609.1
ENST00000589799.1
ENST00000291182.4
ENST00000589248.1
ZNF235
zinc finger protein 235
chr1_+_110163709 0.06 ENST00000369840.2
ENST00000527846.1
AMPD2
adenosine monophosphate deaminase 2
chr1_-_157108130 0.06 ENST00000368192.4
ETV3
ets variant 3
chr18_-_34408693 0.06 ENST00000587382.1
ENST00000589049.1
ENST00000587129.1
TPGS2
tubulin polyglutamylase complex subunit 2
chr16_-_11492366 0.06 ENST00000595360.1
CTD-3088G3.8
Protein LOC388210
chr12_+_53693812 0.06 ENST00000549488.1
C12orf10
chromosome 12 open reading frame 10
chr16_+_28943260 0.06 ENST00000538922.1
ENST00000324662.3
ENST00000567541.1
CD19
CD19 molecule
chr5_-_39425290 0.06 ENST00000545653.1
DAB2
Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr22_-_30968839 0.06 ENST00000445645.1
ENST00000416358.1
ENST00000423371.1
ENST00000411821.1
ENST00000448604.1
GAL3ST1
galactose-3-O-sulfotransferase 1
chr18_+_3262415 0.06 ENST00000581193.1
ENST00000400175.5
MYL12B
myosin, light chain 12B, regulatory
chr7_-_2354099 0.06 ENST00000222990.3
SNX8
sorting nexin 8
chr10_-_49813090 0.06 ENST00000249601.4
ARHGAP22
Rho GTPase activating protein 22
chr4_+_37978891 0.06 ENST00000446803.2
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr11_+_46722368 0.06 ENST00000311764.2
ZNF408
zinc finger protein 408
chr22_+_32340447 0.06 ENST00000248975.5
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta

Network of associatons between targets according to the STRING database.

First level regulatory network of EP300

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 GO:0070424 regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070424)
0.1 0.2 GO:0071348 cellular response to interleukin-11(GO:0071348)
0.1 0.5 GO:0010836 negative regulation of protein ADP-ribosylation(GO:0010836)
0.1 0.2 GO:1990108 protein linear deubiquitination(GO:1990108)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.1 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.1 GO:1903572 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.1 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.0 GO:0051885 positive regulation of anagen(GO:0051885)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0072738 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.0 0.7 GO:0031573 intra-S DNA damage checkpoint(GO:0031573)
0.0 0.1 GO:2000532 renal albumin absorption(GO:0097018) regulation of renal albumin absorption(GO:2000532)
0.0 0.4 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.2 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0060051 negative regulation of protein glycosylation(GO:0060051)
0.0 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0035938 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.0 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.1 GO:0034552 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0070829 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.1 GO:0044053 translocation of peptides or proteins into host(GO:0042000) translocation of peptides or proteins into host cell cytoplasm(GO:0044053) translocation of molecules into host(GO:0044417) translocation of peptides or proteins into other organism involved in symbiotic interaction(GO:0051808) translocation of molecules into other organism involved in symbiotic interaction(GO:0051836)
0.0 0.2 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721)
0.0 0.2 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.1 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.1 GO:0006218 uridine catabolic process(GO:0006218)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.3 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0048625 myoblast fate commitment(GO:0048625)
0.0 0.0 GO:0007506 gonadal mesoderm development(GO:0007506)
0.0 0.1 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.1 GO:0036511 trimming of terminal mannose on B branch(GO:0036509) trimming of first mannose on A branch(GO:0036511) trimming of second mannose on A branch(GO:0036512)
0.0 0.1 GO:1902044 regulation of Fas signaling pathway(GO:1902044)
0.0 0.1 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.1 GO:0034628 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.0 GO:0002663 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0010370 perinucleolar chromocenter(GO:0010370)
0.1 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.6 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 0.3 GO:0036038 MKS complex(GO:0036038)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008384 IkappaB kinase activity(GO:0008384) K48-linked polyubiquitin binding(GO:0036435)
0.0 0.3 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0008260 3-oxoacid CoA-transferase activity(GO:0008260)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.2 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.0 GO:0031751 D4 dopamine receptor binding(GO:0031751)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.1 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.0 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.2 GO:0008061 chitin binding(GO:0008061)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.0 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 1.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.3 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.1 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle