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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for EOMES

Z-value: 0.86

Motif logo

Transcription factors associated with EOMES

Gene Symbol Gene ID Gene Info
ENSG00000163508.8 eomesodermin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
EOMEShg19_v2_chr3_-_27763803_27763822-0.572.4e-01Click!

Activity profile of EOMES motif

Sorted Z-values of EOMES motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_30948600 0.64 ENST00000550292.1
long intergenic non-protein coding RNA 941
chr17_-_18585131 0.59 ENST00000443457.1
ENST00000583002.1
zinc finger protein 286B
chr6_-_86303833 0.58 ENST00000505648.1
sorting nexin 14
chr5_+_443280 0.58 ENST00000508022.1
exocyst complex component 3
chr10_+_103986085 0.56 ENST00000370005.3
ELOVL fatty acid elongase 3
chr6_-_86303523 0.50 ENST00000513865.1
ENST00000369627.2
ENST00000514419.1
ENST00000509338.1
ENST00000314673.3
ENST00000346348.3
sorting nexin 14
chr1_-_167906277 0.49 ENST00000271373.4
mitochondrial pyruvate carrier 2
chr5_+_56205878 0.42 ENST00000423328.1
SET domain containing 9
chr3_-_143567262 0.39 ENST00000474151.1
ENST00000316549.6
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr2_-_192015697 0.37 ENST00000409995.1
signal transducer and activator of transcription 4
chr16_+_24550857 0.35 ENST00000568015.1
retinoblastoma binding protein 6
chr1_+_219347186 0.33 ENST00000366928.5
lysophospholipase-like 1
chr17_+_47439733 0.31 ENST00000507337.1
RP11-1079K10.3
chr1_+_60280458 0.31 ENST00000455990.1
ENST00000371208.3
hook microtubule-tethering protein 1
chr2_+_230787213 0.29 ENST00000409992.1
F-box protein 36
chr14_-_55658323 0.29 ENST00000554067.1
ENST00000247191.2
discs, large (Drosophila) homolog-associated protein 5
chrX_-_119695279 0.29 ENST00000336592.6
cullin 4B
chr19_+_39897943 0.28 ENST00000600033.1
ZFP36 ring finger protein
chr15_+_63414017 0.28 ENST00000413507.2
lactamase, beta
chrX_+_106045891 0.27 ENST00000357242.5
ENST00000310452.2
ENST00000481617.2
ENST00000276175.3
TBC1 domain family, member 8B (with GRAM domain)
chr14_+_57857262 0.27 ENST00000555166.1
ENST00000556492.1
ENST00000554703.1
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr4_-_54930790 0.26 ENST00000263921.3
cysteine-rich hydrophobic domain 2
chr9_-_72374848 0.26 ENST00000377200.5
ENST00000340434.4
ENST00000472967.2
protein prenyltransferase alpha subunit repeat containing 1
chr2_-_99224915 0.26 ENST00000328709.3
ENST00000409997.1
cytochrome c oxidase assembly factor 5
chr14_+_32546145 0.26 ENST00000556611.1
ENST00000539826.2
Rho GTPase activating protein 5
chr2_-_148778258 0.26 ENST00000392857.5
ENST00000457954.1
ENST00000392858.1
ENST00000542387.1
origin recognition complex, subunit 4
chr8_+_117778736 0.26 ENST00000309822.2
ENST00000357148.3
ENST00000517814.1
ENST00000517820.1
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr14_-_55658252 0.26 ENST00000395425.2
discs, large (Drosophila) homolog-associated protein 5
chr1_+_178694408 0.25 ENST00000324778.5
Ral GEF with PH domain and SH3 binding motif 2
chr19_-_42894420 0.25 ENST00000597255.1
ENST00000222032.5
cornifelin
chr11_-_102323489 0.25 ENST00000361236.3
transmembrane protein 123
chr6_-_73935163 0.25 ENST00000370388.3
KH homology domain containing 1-like
chr14_-_64108125 0.24 ENST00000267522.3
WD repeat domain 89
chr14_+_61995722 0.24 ENST00000556347.1
RP11-47I22.4
chr5_+_139028510 0.23 ENST00000502336.1
ENST00000520967.1
ENST00000511048.1
CXXC finger protein 5
chr18_-_33047039 0.23 ENST00000591141.1
ENST00000586741.1
RP11-322E11.5
chr10_-_134145321 0.23 ENST00000368625.4
ENST00000368619.3
ENST00000456004.1
ENST00000368620.2
serine/threonine kinase 32C
chr8_-_90996837 0.23 ENST00000519426.1
ENST00000265433.3
nibrin
chr5_+_32531893 0.23 ENST00000512913.1
SUB1 homolog (S. cerevisiae)
chr1_+_27668505 0.23 ENST00000318074.5
synaptotagmin-like 1
chr12_+_65996599 0.22 ENST00000539116.1
ENST00000541391.1
RP11-221N13.3
chr1_+_100435535 0.22 ENST00000427993.2
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr8_-_90996459 0.22 ENST00000517337.1
ENST00000409330.1
nibrin
chr17_-_4463856 0.22 ENST00000574584.1
ENST00000381550.3
ENST00000301395.3
gamma-glutamyltransferase 6
chr11_-_66056596 0.21 ENST00000471387.2
ENST00000359461.6
ENST00000376901.4
Yip1 interacting factor homolog A (S. cerevisiae)
chr2_-_152118352 0.21 ENST00000331426.5
RNA binding motif protein 43
chr9_+_132044730 0.21 ENST00000455981.1
RP11-344B5.2
chr1_-_146644122 0.21 ENST00000254101.3
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr14_-_53162361 0.21 ENST00000395686.3
ERO1-like (S. cerevisiae)
chr1_-_244615425 0.20 ENST00000366535.3
adenylosuccinate synthase
chr2_-_40006289 0.20 ENST00000260619.6
ENST00000454352.2
THUMP domain containing 2
chr1_-_146644036 0.20 ENST00000425272.2
protein kinase, AMP-activated, beta 2 non-catalytic subunit
chr4_-_4291761 0.20 ENST00000513174.1
Ly1 antibody reactive
chr8_+_86089619 0.20 ENST00000256117.5
ENST00000416274.2
E2F transcription factor 5, p130-binding
chr2_+_45878407 0.19 ENST00000421201.1
protein kinase C, epsilon
chr11_+_1860832 0.19 ENST00000252898.7
troponin I type 2 (skeletal, fast)
chr2_-_148778323 0.19 ENST00000440042.1
ENST00000535373.1
ENST00000540442.1
ENST00000536575.1
origin recognition complex, subunit 4
chr5_+_110073853 0.19 ENST00000513807.1
ENST00000509442.2
solute carrier family 25, member 46
chr3_-_88108192 0.19 ENST00000309534.6
CGG triplet repeat binding protein 1
chr6_-_116989916 0.19 ENST00000368576.3
ENST00000368573.1
zinc finger with UFM1-specific peptidase domain
chr14_+_32546485 0.19 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
Rho GTPase activating protein 5
chr22_-_37545972 0.18 ENST00000216223.5
interleukin 2 receptor, beta
chr1_+_150229554 0.18 ENST00000369111.4
carbonic anhydrase XIV
chr5_-_93447333 0.18 ENST00000395965.3
ENST00000505869.1
ENST00000509163.1
family with sequence similarity 172, member A
chr11_-_64052111 0.18 ENST00000394532.3
ENST00000394531.3
ENST00000309032.3
BCL2-associated agonist of cell death
chr1_-_193029192 0.18 ENST00000417752.1
ENST00000367452.4
ubiquitin carboxyl-terminal hydrolase L5
chr6_+_154360616 0.17 ENST00000229768.5
ENST00000419506.2
ENST00000524163.1
ENST00000414028.2
ENST00000435918.2
ENST00000337049.4
opioid receptor, mu 1
chr1_-_228291136 0.17 ENST00000272139.4
chromosome 1 open reading frame 35
chr14_+_32546274 0.17 ENST00000396582.2
Rho GTPase activating protein 5
chr3_-_43663519 0.17 ENST00000427171.1
ENST00000292246.3
anoctamin 10
chr15_+_63413990 0.17 ENST00000261893.4
lactamase, beta
chr1_-_109203997 0.17 ENST00000370032.5
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr3_-_43147431 0.17 ENST00000441964.1
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr10_-_13342051 0.17 ENST00000479604.1
phytanoyl-CoA 2-hydroxylase
chr12_-_6579808 0.17 ENST00000535180.1
ENST00000400911.3
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr17_-_8066843 0.17 ENST00000404970.3
vesicle-associated membrane protein 2 (synaptobrevin 2)
chr21_-_47604318 0.17 ENST00000291672.5
ENST00000330205.6
spermatogenesis and centriole associated 1-like
chr7_-_91875358 0.17 ENST00000458177.1
ENST00000394507.1
ENST00000340022.2
ENST00000444960.1
KRIT1, ankyrin repeat containing
chr1_+_196788887 0.17 ENST00000320493.5
ENST00000367424.4
ENST00000367421.3
complement factor H-related 1
complement factor H-related 2
chr1_+_15256230 0.16 ENST00000376028.4
ENST00000400798.2
kazrin, periplakin interacting protein
chr19_-_36499521 0.16 ENST00000397428.3
ENST00000503121.1
ENST00000340477.5
ENST00000324444.3
ENST00000490730.1
spectrin repeat containing, nuclear envelope family member 4
chr3_-_49893907 0.16 ENST00000482582.1
TRAF interacting protein
chr12_+_65563329 0.16 ENST00000308330.2
LEM domain containing 3
chrX_-_54070388 0.16 ENST00000415025.1
PHD finger protein 8
chr22_-_46373004 0.15 ENST00000339464.4
wingless-type MMTV integration site family, member 7B
chr1_+_172502244 0.15 ENST00000610051.1
SUN domain containing ossification factor
chr19_-_18391708 0.15 ENST00000600972.1
jun D proto-oncogene
chr6_-_109703634 0.15 ENST00000324953.5
ENST00000310786.4
ENST00000275080.7
ENST00000413644.2
CD164 molecule, sialomucin
chr15_-_52970820 0.15 ENST00000261844.7
ENST00000399202.4
ENST00000562135.1
family with sequence similarity 214, member A
chr19_+_49956426 0.15 ENST00000293350.4
ENST00000540132.1
ENST00000455361.2
ENST00000433981.2
aldehyde dehydrogenase 16 family, member A1
chr2_-_179315786 0.15 ENST00000457633.1
ENST00000438687.3
ENST00000325748.4
protein kinase, interferon-inducible double stranded RNA dependent activator
chr17_-_17723746 0.15 ENST00000577897.1
sterol regulatory element binding transcription factor 1
chr11_+_47270475 0.15 ENST00000481889.2
ENST00000436778.1
ENST00000531660.1
ENST00000407404.1
nuclear receptor subfamily 1, group H, member 3
chr8_-_8318847 0.15 ENST00000521218.1
CTA-398F10.2
chr1_+_186344945 0.14 ENST00000419367.3
ENST00000287859.6
chromosome 1 open reading frame 27
chr19_+_41107249 0.14 ENST00000396819.3
latent transforming growth factor beta binding protein 4
chr17_-_60005365 0.14 ENST00000444766.3
integrator complex subunit 2
chr17_+_74723031 0.14 ENST00000586200.1
methyltransferase like 23
chr9_+_2017063 0.14 ENST00000457226.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr3_+_44379944 0.14 ENST00000396078.3
ENST00000342649.4
T cell activation inhibitor, mitochondrial
chr18_+_76829441 0.14 ENST00000458297.2
ATPase, class II, type 9B
chr1_-_226065330 0.14 ENST00000436966.1
transmembrane protein 63A
chr4_+_8321882 0.14 ENST00000509453.1
ENST00000503186.1
RP11-774O3.2
RP11-774O3.1
chr1_+_172502336 0.14 ENST00000263688.3
SUN domain containing ossification factor
chr18_+_2655849 0.14 ENST00000261598.8
structural maintenance of chromosomes flexible hinge domain containing 1
chr20_-_35274548 0.14 ENST00000262866.4
Src-like-adaptor 2
chr15_-_43029252 0.14 ENST00000563260.1
ENST00000356231.3
codanin 1
chr4_+_17812525 0.14 ENST00000251496.2
non-SMC condensin I complex, subunit G
chr1_-_43751230 0.14 ENST00000523677.1
chromosome 1 open reading frame 210
chr2_+_61108650 0.13 ENST00000295025.8
v-rel avian reticuloendotheliosis viral oncogene homolog
chr9_+_37800758 0.13 ENST00000242323.7
DDB1 and CUL4 associated factor 10
chr5_+_61708582 0.13 ENST00000325324.6
importin 11
chr3_-_182698381 0.13 ENST00000292782.4
DCN1, defective in cullin neddylation 1, domain containing 1
chr10_-_103454876 0.13 ENST00000331272.7
F-box and WD repeat domain containing 4
chr2_+_201171268 0.13 ENST00000423749.1
ENST00000428692.1
ENST00000457757.1
ENST00000453663.1
spermatogenesis associated, serine-rich 2-like
chr2_-_161350305 0.13 ENST00000348849.3
RNA binding motif, single stranded interacting protein 1
chr18_+_2655692 0.13 ENST00000320876.6
structural maintenance of chromosomes flexible hinge domain containing 1
chr19_+_7599597 0.13 ENST00000414982.3
ENST00000450331.3
patatin-like phospholipase domain containing 6
chr7_-_66460563 0.13 ENST00000246868.2
Shwachman-Bodian-Diamond syndrome
chr15_+_40532723 0.13 ENST00000558878.1
ENST00000558183.1
p21 protein (Cdc42/Rac)-activated kinase 6
chr11_+_63655987 0.13 ENST00000509502.2
ENST00000512060.1
MAP/microtubule affinity-regulating kinase 2
chr2_-_101767715 0.13 ENST00000376840.4
ENST00000409318.1
TBC1 domain family, member 8 (with GRAM domain)
chr16_+_3162557 0.13 ENST00000382192.3
ENST00000219091.4
ENST00000444510.2
ENST00000414351.1
zinc finger protein 205
chr3_+_132379154 0.13 ENST00000468022.1
ENST00000473651.1
ENST00000494238.2
ubiquitin-like modifier activating enzyme 5
chr1_+_162760513 0.12 ENST00000367915.1
ENST00000367917.3
ENST00000254521.3
ENST00000367913.1
hydroxysteroid (17-beta) dehydrogenase 7
chr3_+_111805182 0.12 ENST00000430855.1
ENST00000431717.2
ENST00000264848.5
chromosome 3 open reading frame 52
chr5_+_133562095 0.12 ENST00000602919.1
CTD-2410N18.3
chr17_-_27949911 0.12 ENST00000492276.2
ENST00000345068.5
ENST00000584602.1
coronin 6
chr4_-_129208030 0.12 ENST00000503872.1
progesterone receptor membrane component 2
chr15_-_65426174 0.12 ENST00000204549.4
programmed cell death 7
chr1_+_26438289 0.12 ENST00000374271.4
ENST00000374269.1
PDLIM1 interacting kinase 1 like
chr8_+_96037255 0.12 ENST00000286687.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr21_+_38445539 0.12 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
tetratricopeptide repeat domain 3
chr20_-_18038521 0.12 ENST00000278780.6
ovo-like zinc finger 2
chr2_-_74875432 0.12 ENST00000536235.1
ENST00000421985.1
meiosis 1 associated protein
chr19_+_55897699 0.12 ENST00000558131.1
ENST00000558752.1
ENST00000458349.2
ribosomal protein L28
chr2_-_235405168 0.12 ENST00000339728.3
ADP-ribosylation factor-like 4C
chr17_-_17740287 0.12 ENST00000355815.4
ENST00000261646.5
sterol regulatory element binding transcription factor 1
chr14_-_89259080 0.12 ENST00000554922.1
ENST00000352093.5
echinoderm microtubule associated protein like 5
chr6_-_82957433 0.12 ENST00000306270.7
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr18_+_48556470 0.12 ENST00000589076.1
ENST00000590061.1
ENST00000591914.1
ENST00000342988.3
SMAD family member 4
chr16_-_3086927 0.12 ENST00000572449.1
coiled-coil domain containing 64B
chr3_-_131221790 0.12 ENST00000512877.1
ENST00000264995.3
ENST00000511168.1
ENST00000425847.2
mitochondrial ribosomal protein L3
chr12_-_6579833 0.12 ENST00000396308.3
vesicle-associated membrane protein 1 (synaptobrevin 1)
chr2_-_97523721 0.12 ENST00000393537.4
ankyrin repeat domain 39
chr22_-_37584321 0.12 ENST00000397110.2
ENST00000337843.2
C1q and tumor necrosis factor related protein 6
chr17_-_62493131 0.12 ENST00000539111.2
polymerase (DNA directed), gamma 2, accessory subunit
chr17_-_77813186 0.12 ENST00000448310.1
ENST00000269397.4
chromobox homolog 4
chr20_-_43150601 0.12 ENST00000541235.1
ENST00000255175.1
ENST00000342374.4
serine incorporator 3
chr8_+_81397846 0.12 ENST00000379091.4
zinc finger and BTB domain containing 10
chr3_-_122102065 0.12 ENST00000479899.1
ENST00000291458.5
ENST00000497726.1
coiled-coil domain containing 58
chr12_+_54378849 0.12 ENST00000515593.1
homeobox C10
chr5_-_145483932 0.12 ENST00000311450.4
PLAC8-like 1
chr17_-_74533734 0.11 ENST00000589342.1
cytoglobin
chr11_+_706595 0.11 ENST00000531348.1
ENST00000530636.1
EPS8-like 2
chr12_+_31812121 0.11 ENST00000395763.3
methyltransferase like 20
chr2_-_170430277 0.11 ENST00000438035.1
ENST00000453929.2
FAST kinase domains 1
chr10_+_135340859 0.11 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
cytochrome P450, family 2, subfamily E, polypeptide 1
chr11_+_1860682 0.11 ENST00000381906.1
troponin I type 2 (skeletal, fast)
chr16_-_1429010 0.11 ENST00000513783.1
unkempt family zinc finger-like
chr19_-_38085633 0.11 ENST00000593133.1
ENST00000590751.1
ENST00000358744.3
ENST00000328550.2
ENST00000451802.2
zinc finger protein 571
chr17_+_79989937 0.11 ENST00000580965.1
ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
chr14_-_77843390 0.11 ENST00000216468.7
transmembrane emp24 protein transport domain containing 8
chr5_-_94620239 0.11 ENST00000515393.1
multiple C2 domains, transmembrane 1
chr20_+_327668 0.11 ENST00000382291.3
ENST00000609504.1
ENST00000382285.2
neurensin 2
chr19_-_34012674 0.11 ENST00000436370.3
ENST00000397032.4
ENST00000244137.7
peptidase D
chr3_+_9944303 0.11 ENST00000421412.1
ENST00000295980.3
interleukin 17 receptor E
chr1_-_93426998 0.11 ENST00000370310.4
family with sequence similarity 69, member A
chr4_-_129207942 0.11 ENST00000503588.1
progesterone receptor membrane component 2
chr11_+_47270436 0.11 ENST00000395397.3
ENST00000405576.1
nuclear receptor subfamily 1, group H, member 3
chr3_-_43147549 0.10 ENST00000344697.2
protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
chr9_+_139846708 0.10 ENST00000371633.3
lipocalin 12
chr17_+_27895045 0.10 ENST00000580183.2
ENST00000578749.1
ENST00000582829.2
tumor protein p53 inducible protein 13
chr8_+_22429205 0.10 ENST00000520207.1
sorbin and SH3 domain containing 3
chr11_+_117947724 0.10 ENST00000534111.1
transmembrane protease, serine 4
chr7_+_87505544 0.10 ENST00000265728.1
DBF4 homolog (S. cerevisiae)
chr1_-_184943610 0.10 ENST00000367511.3
family with sequence similarity 129, member A
chr18_+_76829385 0.10 ENST00000426216.2
ENST00000307671.7
ENST00000586672.1
ENST00000586722.1
ATPase, class II, type 9B
chr13_-_73301819 0.10 ENST00000377818.3
mitotic spindle organizing protein 1
chr11_+_65686728 0.10 ENST00000312515.2
ENST00000525501.1
DR1-associated protein 1 (negative cofactor 2 alpha)
chr17_-_79269067 0.10 ENST00000288439.5
ENST00000374759.3
solute carrier family 38, member 10
chr19_+_55795493 0.10 ENST00000309383.1
BR serine/threonine kinase 1
chr3_-_135915401 0.10 ENST00000491050.1
male-specific lethal 2 homolog (Drosophila)
chr19_-_3500635 0.10 ENST00000250937.3
deoxyhypusine hydroxylase/monooxygenase
chr22_-_50970506 0.10 ENST00000428989.2
ENST00000403326.1
outer dense fiber of sperm tails 3B
chr1_-_149814478 0.10 ENST00000369161.3
histone cluster 2, H2aa3
chr19_+_49838653 0.10 ENST00000598095.1
ENST00000426897.2
ENST00000323906.4
ENST00000535669.2
ENST00000597602.1
ENST00000595660.1
CD37 molecule
chr1_+_28099700 0.10 ENST00000440806.2
syntaxin 12
chr19_+_7598890 0.10 ENST00000221249.6
ENST00000601668.1
ENST00000601001.1
patatin-like phospholipase domain containing 6
chr6_+_74405501 0.10 ENST00000437994.2
ENST00000422508.2
CD109 molecule
chr17_-_38256973 0.10 ENST00000246672.3
nuclear receptor subfamily 1, group D, member 1
chr11_-_66056478 0.10 ENST00000431556.2
ENST00000528575.1
Yip1 interacting factor homolog A (S. cerevisiae)
chr16_-_21452040 0.10 ENST00000521589.1
nuclear pore complex interacting protein family, member B3
chr7_+_30323923 0.09 ENST00000323037.4
zinc and ring finger 2
chr3_-_183735651 0.09 ENST00000427120.2
ENST00000392579.2
ENST00000382494.2
ENST00000446941.2
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr11_+_537494 0.09 ENST00000270115.7
leucine rich repeat containing 56
chr15_-_56757329 0.09 ENST00000260453.3
meiosis-specific nuclear structural 1
chr17_-_48133054 0.09 ENST00000499842.1
RP11-1094H24.4
chr3_+_44379611 0.09 ENST00000383746.3
ENST00000417237.1
T cell activation inhibitor, mitochondrial
chr6_+_45389893 0.09 ENST00000371432.3
runt-related transcription factor 2

Network of associatons between targets according to the STRING database.

First level regulatory network of EOMES

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.1 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.1 0.5 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.4 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.3 GO:0035668 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.1 0.2 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.3 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.1 0.2 GO:0046080 dUTP metabolic process(GO:0046080) dUTP catabolic process(GO:0046081)
0.1 0.3 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.2 GO:0090149 mitochondrial membrane fission(GO:0090149)
0.0 0.6 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.2 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.0 0.2 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.1 GO:0035262 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) cell proliferation involved in heart valve morphogenesis(GO:0003249) regulation of cell proliferation involved in heart valve morphogenesis(GO:0003250) gonad morphogenesis(GO:0035262)
0.0 0.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.2 GO:0060535 trachea cartilage morphogenesis(GO:0060535) inner medullary collecting duct development(GO:0072061)
0.0 0.2 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.0 0.6 GO:0051601 exocyst localization(GO:0051601)
0.0 0.3 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0060086 circadian temperature homeostasis(GO:0060086)
0.0 0.3 GO:0032485 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.3 GO:0002084 protein depalmitoylation(GO:0002084)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0001189 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.0 0.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.2 GO:0002278 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.0 0.1 GO:0010193 response to ozone(GO:0010193)
0.0 0.3 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.2 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.0 0.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.1 GO:0010728 positive regulation of hydrogen peroxide metabolic process(GO:0010726) regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.1 GO:1900082 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:0097398 response to interleukin-17(GO:0097396) cellular response to interleukin-17(GO:0097398)
0.0 0.3 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.4 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 1.1 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0072709 cellular response to sorbitol(GO:0072709)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.3 GO:0018342 protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0 0.4 GO:0006853 carnitine shuttle(GO:0006853)
0.0 0.1 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.3 GO:0045542 positive regulation of cholesterol biosynthetic process(GO:0045542)
0.0 0.1 GO:2000490 negative regulation of hepatic stellate cell activation(GO:2000490)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.1 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.2 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.0 GO:0071418 cellular response to amine stimulus(GO:0071418)
0.0 0.1 GO:0018352 protein-pyridoxal-5-phosphate linkage(GO:0018352)
0.0 0.2 GO:0044598 polyketide metabolic process(GO:0030638) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.1 GO:0045829 negative regulation of isotype switching(GO:0045829)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.2 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.0 0.0 GO:1901291 negative regulation of double-strand break repair via single-strand annealing(GO:1901291)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.2 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.0 0.1 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.0 0.3 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.1 GO:1901660 calcium ion export(GO:1901660) calcium ion export from cell(GO:1990034)
0.0 0.1 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.2 GO:0015825 L-serine transport(GO:0015825)
0.0 0.1 GO:0021520 spinal cord motor neuron cell fate specification(GO:0021520)
0.0 0.0 GO:1903721 regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.0 0.4 GO:0030870 Mre11 complex(GO:0030870)
0.0 0.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.3 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0 0.5 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0071665 gamma-catenin-TCF7L2 complex(GO:0071665)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.6 GO:0000145 exocyst(GO:0000145)
0.0 0.5 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0031905 early endosome lumen(GO:0031905)
0.0 0.1 GO:0035976 AP1 complex(GO:0035976)
0.0 0.4 GO:0044453 nuclear membrane part(GO:0044453)
0.0 0.3 GO:0005861 troponin complex(GO:0005861)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0034678 smooth muscle contractile fiber(GO:0030485) integrin alpha8-beta1 complex(GO:0034678)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.0 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.2 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.2 GO:0048244 phytanoyl-CoA dioxygenase activity(GO:0048244)
0.1 0.5 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.2 GO:0003955 NAD(P)H dehydrogenase (quinone) activity(GO:0003955) 3-oxoacyl-[acyl-carrier-protein] reductase (NADH) activity(GO:0047025)
0.1 0.2 GO:0004170 dUTP diphosphatase activity(GO:0004170)
0.0 0.6 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.0 0.2 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.0 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.1 GO:0047888 fatty acid peroxidase activity(GO:0047888)
0.0 0.3 GO:0008318 protein prenyltransferase activity(GO:0008318)
0.0 0.2 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 1.0 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.4 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.3 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0005199 structural constituent of cell wall(GO:0005199)
0.0 0.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.0 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.0 0.0 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.0 0.0 GO:0034039 8-oxo-7,8-dihydroguanine DNA N-glycosylase activity(GO:0034039)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.0 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.0 GO:0031626 beta-endorphin binding(GO:0031626)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.1 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.0 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks