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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for EMX1
Z-value: 0.78
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Transcription factors associated with EMX1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| EMX1 | hg19_v2_chr2_+_73144604_73144654 | 0.20 | 7.0e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr4_-_36245561 Show fit | 0.52 |
ENST00000506189.1
|
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 |
|
| chr9_-_75488984 Show fit | 0.52 |
ENST00000423171.1
ENST00000449235.1 ENST00000453787.1 |
RP11-151D14.1 |
|
| chrX_+_13671225 Show fit | 0.51 |
ENST00000545566.1
ENST00000544987.1 ENST00000314720.4 |
transcription elongation factor A (SII) N-terminal and central domain containing |
|
| chr6_-_31107127 Show fit | 0.43 |
ENST00000259845.4
|
psoriasis susceptibility 1 candidate 2 |
|
| chr9_-_3469181 Show fit | 0.41 |
ENST00000366116.2
|
Uncharacterized protein |
|
| chr11_-_111649074 Show fit | 0.40 |
ENST00000534218.1
|
RP11-108O10.2 |
|
| chr7_-_77427676 Show fit | 0.40 |
ENST00000257663.3
|
transmembrane protein 60 |
|
| chr8_+_105235572 Show fit | 0.38 |
ENST00000523362.1
|
regulating synaptic membrane exocytosis 2 |
|
| chr10_+_94451574 Show fit | 0.38 |
ENST00000492654.2
|
hematopoietically expressed homeobox |
|
| chr8_+_97773202 Show fit | 0.35 |
ENST00000519484.1
|
carboxypeptidase Q |
Network of associatons between targets according to the STRING database.
First level regulatory network of EMX1
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | GO:0046520 | sphingoid biosynthetic process(GO:0046520) |
| 0.2 | 0.5 | GO:0071449 | cellular response to lipid hydroperoxide(GO:0071449) |
| 0.1 | 0.5 | GO:0061357 | positive regulation of Wnt protein secretion(GO:0061357) |
| 0.1 | 0.5 | GO:0070777 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.1 | 0.4 | GO:0010621 | negative regulation of transcription by transcription factor localization(GO:0010621) |
| 0.0 | 0.4 | GO:0098814 | spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814) |
| 0.0 | 0.4 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
| 0.0 | 0.4 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 0.1 | 0.3 | GO:0042109 | lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109) positive regulation of interleukin-4 biosynthetic process(GO:0045404) |
| 0.1 | 0.3 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.6 | GO:0017059 | serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211) |
| 0.0 | 0.5 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
| 0.1 | 0.3 | GO:0005879 | axonemal microtubule(GO:0005879) |
| 0.0 | 0.3 | GO:0030123 | AP-3 adaptor complex(GO:0030123) |
| 0.0 | 0.3 | GO:0017101 | aminoacyl-tRNA synthetase multienzyme complex(GO:0017101) |
| 0.0 | 0.3 | GO:0030877 | beta-catenin destruction complex(GO:0030877) |
| 0.1 | 0.2 | GO:0043614 | multi-eIF complex(GO:0043614) translation preinitiation complex(GO:0070993) |
| 0.1 | 0.2 | GO:0097224 | sperm connecting piece(GO:0097224) |
| 0.0 | 0.2 | GO:0071547 | piP-body(GO:0071547) |
| 0.0 | 0.2 | GO:0072558 | NLRP1 inflammasome complex(GO:0072558) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 0.6 | GO:0016454 | serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454) |
| 0.1 | 0.5 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.0 | 0.5 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.0 | 0.5 | GO:0043295 | glutathione binding(GO:0043295) |
| 0.0 | 0.4 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 0.0 | 0.4 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.0 | 0.4 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 0.3 | GO:0031862 | prostanoid receptor binding(GO:0031862) |
| 0.1 | 0.3 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
| 0.1 | 0.3 | GO:0033695 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.2 | PID ALK2 PATHWAY | ALK2 signaling events |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.5 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 0.3 | REACTOME SIGNALING BY FGFR3 MUTANTS | Genes involved in Signaling by FGFR3 mutants |
| 0.0 | 0.3 | REACTOME XENOBIOTICS | Genes involved in Xenobiotics |
| 0.0 | 0.3 | REACTOME THE NLRP3 INFLAMMASOME | Genes involved in The NLRP3 inflammasome |
| 0.0 | 0.3 | REACTOME CD28 DEPENDENT VAV1 PATHWAY | Genes involved in CD28 dependent Vav1 pathway |
| 0.0 | 0.1 | REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR | Genes involved in Thromboxane signalling through TP receptor |
| 0.0 | 0.1 | REACTOME HORMONE LIGAND BINDING RECEPTORS | Genes involved in Hormone ligand-binding receptors |