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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for E2F2_E2F5

Z-value: 0.93

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Transcription factors associated with E2F2_E2F5

Gene Symbol Gene ID Gene Info
ENSG00000007968.6 E2F2
ENSG00000133740.6 E2F5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2F2hg19_v2_chr1_-_23857698_238577330.631.8e-01Click!
E2F5hg19_v2_chr8_+_86121448_861214940.542.7e-01Click!

Activity profile of E2F2_E2F5 motif

Sorted Z-values of E2F2_E2F5 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of E2F2_E2F5

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr10_+_62538248 0.52 ENST00000448257.2
CDK1
cyclin-dependent kinase 1
chr14_-_50154921 0.51 ENST00000553805.2
ENST00000554396.1
ENST00000216367.5
ENST00000539565.2
POLE2
polymerase (DNA directed), epsilon 2, accessory subunit
chr2_-_17935059 0.46 ENST00000448223.2
ENST00000381272.4
ENST00000351948.4
SMC6
structural maintenance of chromosomes 6
chr2_+_17935119 0.44 ENST00000317402.7
GEN1
GEN1 Holliday junction 5' flap endonuclease
chr10_+_62538089 0.44 ENST00000519078.2
ENST00000395284.3
ENST00000316629.4
CDK1
cyclin-dependent kinase 1
chr1_+_25599018 0.43 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
RHD
Rh blood group, D antigen
chr8_-_124408652 0.42 ENST00000287394.5
ATAD2
ATPase family, AAA domain containing 2
chr2_-_17935027 0.39 ENST00000446852.1
SMC6
structural maintenance of chromosomes 6
chr6_+_27114861 0.38 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr10_+_112327425 0.37 ENST00000361804.4
SMC3
structural maintenance of chromosomes 3
chr6_-_35656712 0.36 ENST00000357266.4
ENST00000542713.1
FKBP5
FK506 binding protein 5
chr14_+_36295638 0.36 ENST00000543183.1
BRMS1L
breast cancer metastasis-suppressor 1-like
chrX_-_131623982 0.36 ENST00000370844.1
MBNL3
muscleblind-like splicing regulator 3
chr14_+_36295504 0.35 ENST00000216807.7
BRMS1L
breast cancer metastasis-suppressor 1-like
chr11_+_9595180 0.34 ENST00000450114.2
WEE1
WEE1 G2 checkpoint kinase
chr2_-_136633940 0.34 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6
chr8_-_120868078 0.33 ENST00000313655.4
DSCC1
DNA replication and sister chromatid cohesion 1
chr5_-_36152031 0.33 ENST00000296603.4
LMBRD2
LMBR1 domain containing 2
chr7_-_94285472 0.32 ENST00000437425.2
ENST00000447873.1
ENST00000415788.2
SGCE
sarcoglycan, epsilon
chr15_-_64673665 0.32 ENST00000300035.4
KIAA0101
KIAA0101
chr2_+_17935383 0.32 ENST00000524465.1
ENST00000381254.2
ENST00000532257.1
GEN1
GEN1 Holliday junction 5' flap endonuclease
chr6_-_17706618 0.31 ENST00000262077.2
ENST00000537253.1
NUP153
nucleoporin 153kDa
chr7_-_94285402 0.29 ENST00000428696.2
ENST00000445866.2
SGCE
sarcoglycan, epsilon
chr7_-_94285511 0.29 ENST00000265735.7
SGCE
sarcoglycan, epsilon
chrX_+_123095860 0.28 ENST00000428941.1
STAG2
stromal antigen 2
chr4_+_71859156 0.28 ENST00000286648.5
ENST00000504730.1
ENST00000504952.1
DCK
deoxycytidine kinase
chr1_-_221915418 0.28 ENST00000323825.3
ENST00000366899.3
DUSP10
dual specificity phosphatase 10
chr7_+_94285637 0.27 ENST00000482108.1
ENST00000488574.1
PEG10
paternally expressed 10
chr1_-_91487013 0.27 ENST00000347275.5
ENST00000370440.1
ZNF644
zinc finger protein 644
chr11_-_95523500 0.27 ENST00000540054.1
FAM76B
family with sequence similarity 76, member B
chr1_-_91487770 0.27 ENST00000337393.5
ZNF644
zinc finger protein 644
chr1_+_100598742 0.26 ENST00000370139.1
TRMT13
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr1_-_100598444 0.26 ENST00000535161.1
ENST00000287482.5
SASS6
spindle assembly 6 homolog (C. elegans)
chr15_+_44719996 0.25 ENST00000559793.1
ENST00000558968.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr10_+_102672712 0.25 ENST00000370271.3
ENST00000370269.3
ENST00000609386.1
FAM178A
family with sequence similarity 178, member A
chr5_+_36876833 0.24 ENST00000282516.8
ENST00000448238.2
NIPBL
Nipped-B homolog (Drosophila)
chr6_+_24775641 0.24 ENST00000378054.2
ENST00000476555.1
GMNN
geminin, DNA replication inhibitor
chrX_+_123095890 0.24 ENST00000435215.1
STAG2
stromal antigen 2
chr3_-_169381166 0.23 ENST00000486748.1
MECOM
MDS1 and EVI1 complex locus
chr2_-_55277692 0.23 ENST00000394611.2
RTN4
reticulon 4
chr2_-_55277654 0.22 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
RTN4
reticulon 4
chr7_-_158497431 0.21 ENST00000449727.2
ENST00000409339.3
ENST00000409423.1
ENST00000356309.3
NCAPG2
non-SMC condensin II complex, subunit G2
chr3_+_44803322 0.21 ENST00000481166.2
KIF15
kinesin family member 15
chr11_-_95522639 0.21 ENST00000536839.1
FAM76B
family with sequence similarity 76, member B
chr4_+_30721968 0.21 ENST00000361762.2
PCDH7
protocadherin 7
chrX_+_123095546 0.21 ENST00000371157.3
ENST00000371145.3
ENST00000371144.3
STAG2
stromal antigen 2
chr4_+_154265784 0.20 ENST00000240488.3
MND1
meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr15_+_80987617 0.20 ENST00000258884.4
ENST00000558464.1
ABHD17C
abhydrolase domain containing 17C
chr5_-_79950775 0.20 ENST00000439211.2
DHFR
dihydrofolate reductase
chr5_-_79950371 0.19 ENST00000511032.1
ENST00000504396.1
ENST00000505337.1
DHFR
dihydrofolate reductase
chr11_-_95522907 0.19 ENST00000358780.5
ENST00000542135.1
FAM76B
family with sequence similarity 76, member B
chr1_+_222988464 0.19 ENST00000420335.1
RP11-452F19.3
RP11-452F19.3
chr12_+_133264156 0.19 ENST00000317479.3
ENST00000543589.1
PXMP2
peroxisomal membrane protein 2, 22kDa
chrX_+_24711997 0.19 ENST00000379068.3
ENST00000379059.3
POLA1
polymerase (DNA directed), alpha 1, catalytic subunit
chr7_+_120591170 0.19 ENST00000431467.1
ING3
inhibitor of growth family, member 3
chr22_-_38966172 0.18 ENST00000216024.2
DMC1
DNA meiotic recombinase 1
chr13_+_32889605 0.18 ENST00000380152.3
ENST00000544455.1
ENST00000530893.2
BRCA2
breast cancer 2, early onset
chr7_+_120590803 0.18 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
ING3
inhibitor of growth family, member 3
chr1_-_228645556 0.18 ENST00000366695.2
HIST3H2A
histone cluster 3, H2a
chr15_+_44719970 0.18 ENST00000558966.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr21_-_30365136 0.18 ENST00000361371.5
ENST00000389194.2
ENST00000389195.2
LTN1
listerin E3 ubiquitin protein ligase 1
chr2_-_235405679 0.18 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr11_-_19263145 0.17 ENST00000532666.1
ENST00000527884.1
E2F8
E2F transcription factor 8
chr1_-_23857698 0.17 ENST00000361729.2
E2F2
E2F transcription factor 2
chr6_-_27782548 0.17 ENST00000333151.3
HIST1H2AJ
histone cluster 1, H2aj
chr4_+_129731074 0.17 ENST00000512960.1
ENST00000503785.1
ENST00000514740.1
PHF17
jade family PHD finger 1
chr4_+_129730947 0.16 ENST00000452328.2
ENST00000504089.1
PHF17
jade family PHD finger 1
chr6_-_132272504 0.16 ENST00000367976.3
CTGF
connective tissue growth factor
chr12_-_12849073 0.16 ENST00000332427.2
ENST00000540796.1
GPR19
G protein-coupled receptor 19
chr10_+_73724123 0.16 ENST00000373115.4
CHST3
carbohydrate (chondroitin 6) sulfotransferase 3
chr19_+_36705504 0.16 ENST00000456324.1
ZNF146
zinc finger protein 146
chr14_+_35452169 0.16 ENST00000555557.1
SRP54
signal recognition particle 54kDa
chr7_-_100026280 0.16 ENST00000360951.4
ENST00000398027.2
ENST00000324725.6
ENST00000472716.1
ZCWPW1
zinc finger, CW type with PWWP domain 1
chr2_-_55277512 0.16 ENST00000402434.2
RTN4
reticulon 4
chr6_+_27100811 0.16 ENST00000359193.2
HIST1H2AG
histone cluster 1, H2ag
chrX_-_135849484 0.15 ENST00000370620.1
ENST00000535227.1
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr1_+_222885884 0.15 ENST00000340934.5
BROX
BRO1 domain and CAAX motif containing
chr9_-_99180597 0.15 ENST00000375256.4
ZNF367
zinc finger protein 367
chr14_+_35452104 0.15 ENST00000216774.6
ENST00000546080.1
SRP54
signal recognition particle 54kDa
chr19_-_10305302 0.15 ENST00000592054.1
DNMT1
DNA (cytosine-5-)-methyltransferase 1
chr1_-_28241024 0.15 ENST00000313433.7
ENST00000444045.1
RPA2
replication protein A2, 32kDa
chr1_+_6845497 0.15 ENST00000473578.1
ENST00000557126.1
CAMTA1
calmodulin binding transcription activator 1
chr5_+_43120985 0.14 ENST00000515326.1
ZNF131
zinc finger protein 131
chr6_-_30181133 0.14 ENST00000454678.2
ENST00000434785.1
TRIM26
tripartite motif containing 26
chr15_+_44719790 0.14 ENST00000558791.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr2_+_48010312 0.14 ENST00000540021.1
MSH6
mutS homolog 6
chr3_+_111697843 0.14 ENST00000534857.1
ENST00000273359.3
ENST00000494817.1
ABHD10
abhydrolase domain containing 10
chr15_+_100106155 0.14 ENST00000557785.1
ENST00000558049.1
ENST00000449277.2
MEF2A
myocyte enhancer factor 2A
chr9_+_106856541 0.13 ENST00000286398.7
ENST00000440179.1
ENST00000374793.3
SMC2
structural maintenance of chromosomes 2
chrX_+_100353153 0.13 ENST00000423383.1
ENST00000218507.5
ENST00000403304.2
ENST00000435570.1
CENPI
centromere protein I
chr19_+_36706024 0.13 ENST00000443387.2
ZNF146
zinc finger protein 146
chr2_-_55277436 0.13 ENST00000354474.6
RTN4
reticulon 4
chr11_+_47236489 0.13 ENST00000256996.4
ENST00000378603.3
ENST00000378600.3
ENST00000378601.3
DDB2
damage-specific DNA binding protein 2, 48kDa
chr10_+_96305535 0.13 ENST00000419900.1
ENST00000348459.5
ENST00000394045.1
ENST00000394044.1
ENST00000394036.1
HELLS
helicase, lymphoid-specific
chr2_+_48010221 0.13 ENST00000234420.5
MSH6
mutS homolog 6
chr11_+_74303612 0.13 ENST00000527458.1
ENST00000532497.1
ENST00000530511.1
POLD3
polymerase (DNA-directed), delta 3, accessory subunit
chr20_-_60982330 0.12 ENST00000279101.5
CABLES2
Cdk5 and Abl enzyme substrate 2
chr3_-_14220068 0.12 ENST00000449060.2
ENST00000511155.1
XPC
xeroderma pigmentosum, complementation group C
chr17_-_56065540 0.12 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr3_-_133380731 0.12 ENST00000260810.5
TOPBP1
topoisomerase (DNA) II binding protein 1
chr7_+_94139105 0.12 ENST00000297273.4
CASD1
CAS1 domain containing 1
chr1_+_179263308 0.12 ENST00000426956.1
SOAT1
sterol O-acyltransferase 1
chr5_-_137548997 0.12 ENST00000505120.1
ENST00000394886.2
ENST00000394884.3
CDC23
cell division cycle 23
chr4_+_178230985 0.12 ENST00000264596.3
NEIL3
nei endonuclease VIII-like 3 (E. coli)
chr16_-_72698834 0.12 ENST00000570152.1
ENST00000561611.2
ENST00000570035.1
AC004158.2
AC004158.2
chr15_+_100106244 0.12 ENST00000557942.1
MEF2A
myocyte enhancer factor 2A
chr14_+_74551650 0.12 ENST00000554938.1
LIN52
lin-52 homolog (C. elegans)
chr10_+_13203543 0.12 ENST00000378714.3
ENST00000479669.1
ENST00000484800.2
MCM10
minichromosome maintenance complex component 10
chr15_+_44719394 0.11 ENST00000260327.4
ENST00000396780.1
CTDSPL2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr8_-_98290087 0.11 ENST00000322128.3
TSPYL5
TSPY-like 5
chr15_+_47476275 0.11 ENST00000558014.1
SEMA6D
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr1_-_23670817 0.11 ENST00000478691.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr18_+_2655849 0.11 ENST00000261598.8
SMCHD1
structural maintenance of chromosomes flexible hinge domain containing 1
chr1_+_100598691 0.11 ENST00000370143.1
ENST00000370141.2
TRMT13
tRNA methyltransferase 13 homolog (S. cerevisiae)
chr19_+_46144884 0.11 ENST00000593161.1
AC006132.1
chromosome 19 open reading frame 83
chr3_+_14219858 0.11 ENST00000306024.3
LSM3
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr4_+_148538517 0.11 ENST00000296582.3
ENST00000508208.1
TMEM184C
transmembrane protein 184C
chr1_-_39325431 0.11 ENST00000373001.3
RRAGC
Ras-related GTP binding C
chr3_+_127317705 0.11 ENST00000480910.1
MCM2
minichromosome maintenance complex component 2
chr7_-_6048702 0.11 ENST00000265849.7
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr9_+_106856831 0.11 ENST00000303219.8
ENST00000374787.3
SMC2
structural maintenance of chromosomes 2
chr1_-_180471947 0.11 ENST00000367595.3
ACBD6
acyl-CoA binding domain containing 6
chr7_-_27169801 0.10 ENST00000511914.1
HOXA4
homeobox A4
chr11_+_9406169 0.10 ENST00000379719.3
ENST00000527431.1
IPO7
importin 7
chr2_-_203103281 0.10 ENST00000392244.3
ENST00000409181.1
ENST00000409712.1
ENST00000409498.2
ENST00000409368.1
ENST00000392245.1
ENST00000392246.2
SUMO1
small ubiquitin-like modifier 1
chr13_+_114238997 0.10 ENST00000538138.1
ENST00000375370.5
TFDP1
transcription factor Dp-1
chr4_-_170679024 0.10 ENST00000393381.2
C4orf27
chromosome 4 open reading frame 27
chr11_+_13299186 0.10 ENST00000527998.1
ENST00000396441.3
ENST00000533520.1
ENST00000529825.1
ENST00000389707.4
ENST00000401424.1
ENST00000529388.1
ENST00000530357.1
ENST00000403290.1
ENST00000361003.4
ENST00000389708.3
ENST00000403510.3
ENST00000482049.1
ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr4_-_130014532 0.10 ENST00000506368.1
ENST00000439369.2
ENST00000503215.1
SCLT1
sodium channel and clathrin linker 1
chr19_-_13030071 0.10 ENST00000293695.7
SYCE2
synaptonemal complex central element protein 2
chr5_+_36152163 0.09 ENST00000274255.6
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr3_+_57261743 0.09 ENST00000288266.3
APPL1
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr11_+_62623621 0.09 ENST00000535296.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr2_-_174830430 0.09 ENST00000310015.6
ENST00000455789.2
SP3
Sp3 transcription factor
chr19_-_409134 0.09 ENST00000332235.6
C2CD4C
C2 calcium-dependent domain containing 4C
chr1_-_23670752 0.09 ENST00000302271.6
ENST00000426846.2
ENST00000427764.2
ENST00000606561.1
ENST00000374616.3
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr20_-_5100591 0.09 ENST00000379143.5
PCNA
proliferating cell nuclear antigen
chr12_+_109535923 0.09 ENST00000336865.2
UNG
uracil-DNA glycosylase
chr15_+_71184931 0.09 ENST00000560369.1
ENST00000260382.5
LRRC49
leucine rich repeat containing 49
chr6_-_30181156 0.09 ENST00000418026.1
ENST00000416596.1
ENST00000453195.1
TRIM26
tripartite motif containing 26
chr5_+_93954039 0.09 ENST00000265140.5
ANKRD32
ankyrin repeat domain 32
chr5_-_122759032 0.09 ENST00000510582.3
ENST00000328236.5
ENST00000306481.6
ENST00000508442.2
ENST00000395431.2
CEP120
centrosomal protein 120kDa
chr1_+_179262905 0.09 ENST00000539888.1
ENST00000540564.1
ENST00000535686.1
ENST00000367619.3
SOAT1
sterol O-acyltransferase 1
chr5_+_36152179 0.09 ENST00000508514.1
ENST00000513151.1
ENST00000546211.1
SKP2
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase
chr1_-_222885770 0.09 ENST00000355727.2
ENST00000340020.6
AIDA
axin interactor, dorsalization associated
chr9_-_123639600 0.09 ENST00000373896.3
PHF19
PHD finger protein 19
chr3_-_52719888 0.08 ENST00000458294.1
PBRM1
polybromo 1
chr8_+_69242957 0.08 ENST00000518698.1
ENST00000539993.1
C8orf34
chromosome 8 open reading frame 34
chr15_+_40987327 0.08 ENST00000423169.2
ENST00000267868.3
ENST00000557850.1
ENST00000532743.1
ENST00000382643.3
RAD51
RAD51 recombinase
chrX_-_131623874 0.08 ENST00000436215.1
MBNL3
muscleblind-like splicing regulator 3
chr12_-_77459306 0.08 ENST00000547316.1
ENST00000416496.2
ENST00000550669.1
ENST00000322886.7
E2F7
E2F transcription factor 7
chrX_+_102000893 0.08 ENST00000447531.1
ENST00000448867.1
BHLHB9
basic helix-loop-helix domain containing, class B, 9
chr11_+_62623512 0.08 ENST00000377892.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr11_+_62623544 0.08 ENST00000377890.2
ENST00000377891.2
ENST00000377889.2
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr15_+_71185148 0.08 ENST00000443425.2
ENST00000560755.1
LRRC49
leucine rich repeat containing 49
chr15_+_100106126 0.08 ENST00000558812.1
ENST00000338042.6
MEF2A
myocyte enhancer factor 2A
chr8_+_48873479 0.08 ENST00000262105.2
MCM4
minichromosome maintenance complex component 4
chr2_-_54014055 0.08 ENST00000263634.3
ENST00000406687.1
GPR75-ASB3
GPR75-ASB3 readthrough
chr1_-_23670813 0.08 ENST00000374612.1
HNRNPR
heterogeneous nuclear ribonucleoprotein R
chr6_+_116575329 0.08 ENST00000430252.2
ENST00000540275.1
ENST00000448740.2
DSE
RP3-486I3.7
dermatan sulfate epimerase
RP3-486I3.7
chr1_-_205719295 0.08 ENST00000367142.4
NUCKS1
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr2_-_54014127 0.08 ENST00000394717.2
GPR75-ASB3
GPR75-ASB3 readthrough
chr1_-_36235529 0.08 ENST00000318121.3
ENST00000373220.3
ENST00000520551.1
CLSPN
claspin
chrX_+_106871713 0.08 ENST00000372435.4
ENST00000372428.4
ENST00000372419.3
ENST00000543248.1
PRPS1
phosphoribosyl pyrophosphate synthetase 1
chr6_+_24775153 0.08 ENST00000356509.3
ENST00000230056.3
GMNN
geminin, DNA replication inhibitor
chr2_-_219433014 0.08 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
USP37
ubiquitin specific peptidase 37
chr6_-_27775694 0.08 ENST00000377401.2
HIST1H2BL
histone cluster 1, H2bl
chr3_-_10028366 0.08 ENST00000429759.1
EMC3
ER membrane protein complex subunit 3
chr8_-_67525473 0.07 ENST00000522677.3
MYBL1
v-myb avian myeloblastosis viral oncogene homolog-like 1
chr17_+_74734052 0.07 ENST00000590514.1
MFSD11
major facilitator superfamily domain containing 11
chr3_-_169381183 0.07 ENST00000494292.1
MECOM
MDS1 and EVI1 complex locus
chr10_-_58120996 0.07 ENST00000361148.6
ENST00000395405.1
ENST00000373944.3
ZWINT
ZW10 interacting kinetochore protein
chr9_-_131940526 0.07 ENST00000372491.2
IER5L
immediate early response 5-like
chr7_-_105517021 0.07 ENST00000318724.4
ENST00000419735.3
ATXN7L1
ataxin 7-like 1
chr16_-_47495170 0.07 ENST00000320640.6
ENST00000544001.2
ITFG1
integrin alpha FG-GAP repeat containing 1
chr1_+_228645796 0.07 ENST00000369160.2
HIST3H2BB
histone cluster 3, H2bb
chr8_+_48873453 0.07 ENST00000523944.1
MCM4
minichromosome maintenance complex component 4
chr9_+_86595626 0.07 ENST00000445877.1
ENST00000325875.3
RMI1
RecQ mediated genome instability 1
chr13_-_73356009 0.07 ENST00000377780.4
ENST00000377767.4
DIS3
DIS3 mitotic control homolog (S. cerevisiae)
chr9_+_17135016 0.07 ENST00000425824.1
ENST00000262360.5
ENST00000380641.4
CNTLN
centlein, centrosomal protein
chr12_-_48499591 0.07 ENST00000551330.1
ENST00000004980.5
ENST00000339976.6
ENST00000448372.1
SENP1
SUMO1/sentrin specific peptidase 1
chr5_-_122758994 0.07 ENST00000306467.5
ENST00000515110.1
CEP120
centrosomal protein 120kDa
chr18_-_54318353 0.07 ENST00000590954.1
ENST00000540155.1
TXNL1
thioredoxin-like 1
chr5_+_140019079 0.07 ENST00000252100.6
TMCO6
transmembrane and coiled-coil domains 6
chr9_+_17134980 0.07 ENST00000380647.3
CNTLN
centlein, centrosomal protein
chrX_-_57937067 0.07 ENST00000358697.4
ZXDA
zinc finger, X-linked, duplicated A
chr7_+_86781916 0.07 ENST00000579592.1
ENST00000434534.1
DMTF1
cyclin D binding myb-like transcription factor 1
chr1_-_212208842 0.07 ENST00000366992.3
ENST00000366993.3
ENST00000440600.2
ENST00000366994.3
INTS7
integrator complex subunit 7
chrX_-_62974941 0.07 ENST00000374872.1
ENST00000253401.6
ENST00000374870.4
ARHGEF9
Cdc42 guanine nucleotide exchange factor (GEF) 9
chr7_-_44887620 0.07 ENST00000349299.3
ENST00000521529.1
ENST00000308153.4
ENST00000350771.3
ENST00000222690.6
ENST00000381124.5
ENST00000437072.1
ENST00000446531.1
H2AFV
H2A histone family, member V
chr7_+_116593536 0.07 ENST00000417919.1
ST7
suppression of tumorigenicity 7
chr9_-_123639445 0.07 ENST00000312189.6
PHF19
PHD finger protein 19
chr4_-_174256276 0.07 ENST00000296503.5
HMGB2
high mobility group box 2
chrX_-_106243451 0.07 ENST00000355610.4
ENST00000535534.1
MORC4
MORC family CW-type zinc finger 4
chr10_+_96305610 0.07 ENST00000371332.4
ENST00000239026.6
HELLS
helicase, lymphoid-specific
chrX_-_122866874 0.07 ENST00000245838.8
ENST00000355725.4
THOC2
THO complex 2
chr7_+_116593568 0.07 ENST00000446490.1
ST7
suppression of tumorigenicity 7
chr1_-_149982624 0.07 ENST00000417191.1
ENST00000369135.4
OTUD7B
OTU domain containing 7B
chr4_+_129730779 0.07 ENST00000226319.6
PHF17
jade family PHD finger 1
chr17_+_48796905 0.06 ENST00000505658.1
ENST00000393227.2
ENST00000240304.1
ENST00000311571.3
ENST00000505619.1
ENST00000544170.1
ENST00000510984.1
LUC7L3
LUC7-like 3 (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0071140 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.1 1.0 GO:0014038 regulation of Schwann cell differentiation(GO:0014038)
0.1 0.3 GO:0046832 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.1 0.4 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.1 0.3 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.1 0.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.2 GO:0035261 external genitalia morphogenesis(GO:0035261)
0.1 1.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.3 GO:0006617 SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition(GO:0006617)
0.1 0.3 GO:0006272 leading strand elongation(GO:0006272)
0.1 0.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.8 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.1 0.3 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536) regulation of respiratory burst involved in inflammatory response(GO:0060264) negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.2 GO:0034059 response to anoxia(GO:0034059)
0.1 0.6 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.3 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.3 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.0 0.0 GO:0036388 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0 0.3 GO:0060356 leucine import(GO:0060356)
0.0 0.2 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.3 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:1901896 positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0 0.2 GO:0042148 strand invasion(GO:0042148)
0.0 0.2 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.7 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0 0.6 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.0 GO:0051300 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.0 0.2 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.0 GO:1901069 purine nucleobase salvage(GO:0043096) guanosine-containing compound catabolic process(GO:1901069)
0.0 0.3 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157)
0.0 0.1 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.1 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917)
0.0 0.1 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.0 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:0097125 cyclin B1-CDK1 complex(GO:0097125)
0.2 0.9 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.8 GO:0035061 interchromatin granule(GO:0035061)
0.1 0.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.3 GO:0032301 MutSalpha complex(GO:0032301)
0.1 0.4 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.2 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0098536 deuterosome(GO:0098536)
0.0 0.5 GO:0000796 condensin complex(GO:0000796)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0005873 plus-end kinesin complex(GO:0005873)
0.0 0.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.0 0.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.1 GO:0031251 PAN complex(GO:0031251)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.7 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.3 GO:0000800 lateral element(GO:0000800)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.3 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.0 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.0 0.0 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0032389 MutLalpha complex(GO:0032389)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0036033 mediator complex binding(GO:0036033)
0.1 0.2 GO:0034736 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.1 0.1 GO:0000404 heteroduplex DNA loop binding(GO:0000404)
0.1 0.4 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.3 GO:0032143 single thymine insertion binding(GO:0032143)
0.1 0.8 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.1 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.0 0.3 GO:0004137 deoxycytidine kinase activity(GO:0004137)
0.0 0.1 GO:0032135 DNA insertion or deletion binding(GO:0032135)
0.0 1.0 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.4 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) chondroitin sulfotransferase activity(GO:0034481)
0.0 0.1 GO:0097363 protein O-GlcNAc transferase activity(GO:0097363)
0.0 0.1 GO:0031177 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 0.3 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.0 0.1 GO:0044378 non-sequence-specific DNA binding, bending(GO:0044378)
0.0 0.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.4 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.9 PID ATR PATHWAY ATR signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.2 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.7 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.4 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.1 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 0.5 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage