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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for DLX1_HOXA3_BARX2

Z-value: 0.63

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Transcription factors associated with DLX1_HOXA3_BARX2

Gene Symbol Gene ID Gene Info
DLX1
ENSG00000144355.10 distal-less homeobox 1
HOXA3
ENSG00000105997.18 homeobox A3
BARX2
ENSG00000043039.5 BARX homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DLX1hg19_v2_chr2_+_172950227_1729502640.473.4e-01Click!
HOXA3hg19_v2_chr7_-_27153454_271534690.315.5e-01Click!
BARX2hg19_v2_chr11_+_129245796_1292458350.088.8e-01Click!

Activity profile of DLX1_HOXA3_BARX2 motif

Sorted Z-values of DLX1_HOXA3_BARX2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_57229155 0.73 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr5_+_136070614 0.71 ENST00000502421.1
CTB-1I21.1
CTB-1I21.1
chr11_-_63376013 0.56 ENST00000540943.1
PLA2G16
phospholipase A2, group XVI
chr12_+_78359999 0.53 ENST00000550503.1
NAV3
neuron navigator 3
chr16_+_53412368 0.51 ENST00000565189.1
RP11-44F14.2
RP11-44F14.2
chr5_-_150473127 0.44 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr1_-_197115818 0.42 ENST00000367409.4
ENST00000294732.7
ASPM
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
chr1_+_152784447 0.37 ENST00000360090.3
LCE1B
late cornified envelope 1B
chr18_-_59415987 0.37 ENST00000590199.1
ENST00000590968.1
RP11-879F14.1
RP11-879F14.1
chr7_+_37723336 0.35 ENST00000450180.1
GPR141
G protein-coupled receptor 141
chr17_+_61151306 0.35 ENST00000580068.1
ENST00000580466.1
TANC2
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
chr9_-_5339873 0.35 ENST00000223862.1
ENST00000223858.4
RLN1
relaxin 1
chr19_+_45417921 0.31 ENST00000252491.4
ENST00000592885.1
ENST00000589781.1
APOC1
apolipoprotein C-I
chr11_-_60010556 0.31 ENST00000427611.2
MS4A4E
membrane-spanning 4-domains, subfamily A, member 4E
chr9_-_5304432 0.30 ENST00000416837.1
ENST00000308420.3
RLN2
relaxin 2
chr7_-_99716952 0.30 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chrX_+_150565653 0.30 ENST00000330374.6
VMA21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr7_-_99716940 0.29 ENST00000440225.1
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr12_+_28410128 0.28 ENST00000381259.1
ENST00000381256.1
CCDC91
coiled-coil domain containing 91
chr4_+_88896819 0.26 ENST00000237623.7
ENST00000395080.3
ENST00000508233.1
ENST00000360804.4
SPP1
secreted phosphoprotein 1
chr15_+_63682335 0.26 ENST00000559379.1
ENST00000559821.1
RP11-321G12.1
RP11-321G12.1
chr1_-_21620877 0.26 ENST00000527991.1
ECE1
endothelin converting enzyme 1
chr19_+_40873617 0.25 ENST00000599353.1
PLD3
phospholipase D family, member 3
chr15_+_35270552 0.25 ENST00000391457.2
AC114546.1
HCG37415; PRO1914; Uncharacterized protein
chr6_-_32908765 0.25 ENST00000416244.2
HLA-DMB
major histocompatibility complex, class II, DM beta
chr5_+_148443049 0.24 ENST00000515304.1
ENST00000507318.1
CTC-529P8.1
CTC-529P8.1
chr11_+_5775923 0.24 ENST00000317254.3
OR52N4
olfactory receptor, family 52, subfamily N, member 4 (gene/pseudogene)
chr7_-_99716914 0.23 ENST00000431404.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr20_-_56265680 0.23 ENST00000414037.1
PMEPA1
prostate transmembrane protein, androgen induced 1
chr8_-_8639956 0.22 ENST00000522213.1
RP11-211C9.1
RP11-211C9.1
chr16_+_53133070 0.22 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr4_-_103749313 0.22 ENST00000394803.5
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr4_-_69536346 0.21 ENST00000338206.5
UGT2B15
UDP glucuronosyltransferase 2 family, polypeptide B15
chr12_+_8276433 0.20 ENST00000345999.3
ENST00000352620.3
ENST00000360500.3
CLEC4A
C-type lectin domain family 4, member A
chr2_+_149402989 0.20 ENST00000397424.2
EPC2
enhancer of polycomb homolog 2 (Drosophila)
chr6_+_46761118 0.19 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr6_+_149721495 0.19 ENST00000326669.4
SUMO4
small ubiquitin-like modifier 4
chr7_-_99717463 0.19 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr15_+_96904487 0.18 ENST00000600790.1
AC087477.1
Uncharacterized protein
chr11_-_26593779 0.18 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr10_-_115904361 0.18 ENST00000428953.1
ENST00000543782.1
C10orf118
chromosome 10 open reading frame 118
chr16_-_28937027 0.18 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr3_+_98482175 0.17 ENST00000485391.1
ENST00000492254.1
ST3GAL6
ST3 beta-galactoside alpha-2,3-sialyltransferase 6
chr19_+_17638059 0.17 ENST00000599164.1
ENST00000449408.2
ENST00000600871.1
ENST00000599124.1
FAM129C
family with sequence similarity 129, member C
chr6_-_28411241 0.17 ENST00000289788.4
ZSCAN23
zinc finger and SCAN domain containing 23
chr10_+_81891416 0.17 ENST00000372270.2
PLAC9
placenta-specific 9
chr16_-_25122735 0.17 ENST00000563176.1
RP11-449H11.1
RP11-449H11.1
chr5_+_66300464 0.17 ENST00000436277.1
MAST4
microtubule associated serine/threonine kinase family member 4
chr12_+_48592134 0.17 ENST00000595310.1
DKFZP779L1853
DKFZP779L1853
chr13_-_30880979 0.16 ENST00000414289.1
KATNAL1
katanin p60 subunit A-like 1
chr6_+_88106840 0.16 ENST00000369570.4
C6orf164
chromosome 6 open reading frame 164
chr4_-_79860506 0.16 ENST00000295462.3
ENST00000380645.4
ENST00000512733.1
PAQR3
progestin and adipoQ receptor family member III
chr5_+_66300446 0.16 ENST00000261569.7
MAST4
microtubule associated serine/threonine kinase family member 4
chr7_-_92777606 0.16 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr16_+_58010339 0.16 ENST00000290871.5
ENST00000441824.2
TEPP
testis, prostate and placenta expressed
chr3_+_51851612 0.15 ENST00000456080.1
IQCF3
IQ motif containing F3
chr5_-_139726181 0.15 ENST00000507104.1
ENST00000230990.6
HBEGF
heparin-binding EGF-like growth factor
chr12_+_64798095 0.15 ENST00000332707.5
XPOT
exportin, tRNA
chr2_-_203735484 0.15 ENST00000420558.1
ENST00000418208.1
ICA1L
islet cell autoantigen 1,69kDa-like
chr12_-_76461249 0.15 ENST00000551524.1
NAP1L1
nucleosome assembly protein 1-like 1
chr3_+_138340049 0.14 ENST00000464668.1
FAIM
Fas apoptotic inhibitory molecule
chr2_+_191221240 0.13 ENST00000409027.1
ENST00000458193.1
INPP1
inositol polyphosphate-1-phosphatase
chr15_+_41057818 0.13 ENST00000558467.1
GCHFR
GTP cyclohydrolase I feedback regulator
chr1_+_1846519 0.13 ENST00000378604.3
CALML6
calmodulin-like 6
chr7_+_107224364 0.13 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr19_-_36606181 0.13 ENST00000221859.4
POLR2I
polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
chr7_-_35013217 0.13 ENST00000446375.1
DPY19L1
dpy-19-like 1 (C. elegans)
chr4_-_103749105 0.13 ENST00000394801.4
ENST00000394804.2
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr12_+_22852791 0.13 ENST00000413794.2
RP11-114G22.1
RP11-114G22.1
chr17_-_72772425 0.13 ENST00000578822.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr11_+_24518723 0.13 ENST00000336930.6
ENST00000529015.1
ENST00000533227.1
LUZP2
leucine zipper protein 2
chr18_-_33709268 0.13 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr11_+_18154059 0.13 ENST00000531264.1
MRGPRX3
MAS-related GPR, member X3
chr17_-_72772462 0.13 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9
N-acetyltransferase 9 (GCN5-related, putative)
chr15_+_94899183 0.13 ENST00000557742.1
MCTP2
multiple C2 domains, transmembrane 2
chr3_-_33686925 0.13 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2
cytoplasmic linker associated protein 2
chr8_-_55014018 0.12 ENST00000521352.1
LYPLA1
lysophospholipase I
chr21_-_19858196 0.12 ENST00000422787.1
TMPRSS15
transmembrane protease, serine 15
chr7_+_134528635 0.12 ENST00000445569.2
CALD1
caldesmon 1
chrX_+_107288280 0.12 ENST00000458383.1
VSIG1
V-set and immunoglobulin domain containing 1
chr17_+_67759813 0.12 ENST00000587241.1
AC003051.1
AC003051.1
chr10_+_94594351 0.12 ENST00000371552.4
EXOC6
exocyst complex component 6
chr10_+_18549645 0.11 ENST00000396576.2
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr4_-_119759795 0.11 ENST00000419654.2
SEC24D
SEC24 family member D
chr12_+_38710555 0.11 ENST00000551464.1
ALG10B
ALG10B, alpha-1,2-glucosyltransferase
chr19_+_50016610 0.11 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr9_+_125133467 0.11 ENST00000426608.1
PTGS1
prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)
chr7_-_7575477 0.11 ENST00000399429.3
COL28A1
collagen, type XXVIII, alpha 1
chr8_+_105602961 0.11 ENST00000521923.1
RP11-127H5.1
Uncharacterized protein
chr14_-_45252031 0.11 ENST00000556405.1
RP11-398E10.1
RP11-398E10.1
chr15_+_58702742 0.11 ENST00000356113.6
ENST00000414170.3
LIPC
lipase, hepatic
chr5_+_53686658 0.11 ENST00000512618.1
LINC01033
long intergenic non-protein coding RNA 1033
chr2_+_17997763 0.11 ENST00000281047.3
MSGN1
mesogenin 1
chr17_-_57158523 0.11 ENST00000581468.1
TRIM37
tripartite motif containing 37
chr4_+_189321881 0.10 ENST00000512839.1
ENST00000513313.1
LINC01060
long intergenic non-protein coding RNA 1060
chr7_-_86849836 0.10 ENST00000455575.1
TMEM243
transmembrane protein 243, mitochondrial
chr9_-_128246769 0.10 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr11_+_89764274 0.10 ENST00000448984.1
ENST00000432771.1
TRIM49C
tripartite motif containing 49C
chr12_+_26348246 0.10 ENST00000422622.2
SSPN
sarcospan
chr6_-_47445214 0.10 ENST00000604014.1
RP11-385F7.1
RP11-385F7.1
chr17_-_12920907 0.10 ENST00000609757.1
ENST00000581499.2
ENST00000580504.1
ELAC2
elaC ribonuclease Z 2
chr19_-_3985455 0.10 ENST00000309311.6
EEF2
eukaryotic translation elongation factor 2
chr7_+_148936732 0.10 ENST00000335870.2
ZNF212
zinc finger protein 212
chrX_-_23926004 0.10 ENST00000379226.4
ENST00000379220.3
APOO
apolipoprotein O
chr11_-_64684672 0.10 ENST00000377264.3
ENST00000421419.2
ATG2A
autophagy related 2A
chr19_-_3557570 0.10 ENST00000355415.2
MFSD12
major facilitator superfamily domain containing 12
chr4_+_56814968 0.10 ENST00000422247.2
CEP135
centrosomal protein 135kDa
chr10_+_6779326 0.10 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr11_+_59705928 0.10 ENST00000398992.1
OOSP1
oocyte secreted protein 1
chr12_-_48164812 0.10 ENST00000549151.1
ENST00000548919.1
RAPGEF3
Rap guanine nucleotide exchange factor (GEF) 3
chr8_-_93978309 0.10 ENST00000517858.1
ENST00000378861.5
TRIQK
triple QxxK/R motif containing
chr6_+_134273321 0.10 ENST00000457715.1
TBPL1
TBP-like 1
chr19_+_21579908 0.10 ENST00000596302.1
ENST00000392288.2
ENST00000594390.1
ENST00000355504.4
ZNF493
zinc finger protein 493
chr19_+_23257988 0.10 ENST00000594318.1
ENST00000600223.1
ENST00000593635.1
CTD-2291D10.4
ZNF730
CTD-2291D10.4
zinc finger protein 730
chr16_-_1464688 0.10 ENST00000389221.4
ENST00000508903.2
ENST00000397462.1
ENST00000301712.5
UNKL
unkempt family zinc finger-like
chr6_+_134273300 0.10 ENST00000416965.1
TBPL1
TBP-like 1
chr19_+_21579958 0.10 ENST00000339914.6
ENST00000599461.1
ZNF493
zinc finger protein 493
chr4_+_80584903 0.10 ENST00000506460.1
RP11-452C8.1
RP11-452C8.1
chr4_-_103749205 0.10 ENST00000508249.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr7_-_55620433 0.09 ENST00000418904.1
VOPP1
vesicular, overexpressed in cancer, prosurvival protein 1
chr1_-_222763101 0.09 ENST00000391883.2
ENST00000366890.1
TAF1A
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
chr16_+_12059091 0.09 ENST00000562385.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr15_+_43885799 0.09 ENST00000449946.1
ENST00000417289.1
CKMT1B
creatine kinase, mitochondrial 1B
chr6_-_82957433 0.09 ENST00000306270.7
IBTK
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr9_-_100684769 0.09 ENST00000455506.1
ENST00000375117.4
C9orf156
chromosome 9 open reading frame 156
chr6_-_116833500 0.09 ENST00000356128.4
TRAPPC3L
trafficking protein particle complex 3-like
chrX_-_115594160 0.09 ENST00000371894.4
CXorf61
cancer/testis antigen 83
chr9_-_103115135 0.09 ENST00000537512.1
TEX10
testis expressed 10
chr19_+_49199209 0.09 ENST00000522966.1
ENST00000425340.2
ENST00000391876.4
FUT2
fucosyltransferase 2 (secretor status included)
chr7_+_150020363 0.09 ENST00000359623.4
ENST00000493307.1
LRRC61
leucine rich repeat containing 61
chr3_+_138340067 0.09 ENST00000479848.1
FAIM
Fas apoptotic inhibitory molecule
chr4_-_112993808 0.09 ENST00000511219.1
RP11-269F21.3
RP11-269F21.3
chr1_+_149239529 0.09 ENST00000457216.2
RP11-403I13.4
RP11-403I13.4
chr21_+_33671160 0.09 ENST00000303645.5
MRAP
melanocortin 2 receptor accessory protein
chr3_-_33686743 0.09 ENST00000333778.6
ENST00000539981.1
CLASP2
cytoplasmic linker associated protein 2
chr6_+_26402465 0.09 ENST00000476549.2
ENST00000289361.6
ENST00000450085.2
ENST00000425234.2
ENST00000427334.1
ENST00000506698.1
BTN3A1
butyrophilin, subfamily 3, member A1
chr17_-_15501932 0.09 ENST00000583965.1
CDRT1
CMT1A duplicated region transcript 1
chr21_-_35796241 0.09 ENST00000450895.1
AP000322.53
AP000322.53
chr6_-_133035185 0.09 ENST00000367928.4
VNN1
vanin 1
chr2_-_165630264 0.09 ENST00000452626.1
COBLL1
cordon-bleu WH2 repeat protein-like 1
chr8_-_93978333 0.09 ENST00000524037.1
ENST00000520430.1
ENST00000521617.1
TRIQK
triple QxxK/R motif containing
chr7_+_138915102 0.09 ENST00000486663.1
UBN2
ubinuclein 2
chr7_-_64023441 0.09 ENST00000309683.6
ZNF680
zinc finger protein 680
chr16_+_28889801 0.09 ENST00000395503.4
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr12_-_719573 0.09 ENST00000397265.3
NINJ2
ninjurin 2
chr4_-_175041663 0.08 ENST00000503140.1
RP11-148L24.1
RP11-148L24.1
chr11_-_327537 0.08 ENST00000602735.1
IFITM3
interferon induced transmembrane protein 3
chr3_-_98235962 0.08 ENST00000513873.1
CLDND1
claudin domain containing 1
chrX_-_20236970 0.08 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr8_+_94752349 0.08 ENST00000391680.1
RBM12B-AS1
RBM12B antisense RNA 1
chr14_-_39639523 0.08 ENST00000330149.5
ENST00000554018.1
ENST00000347691.5
TRAPPC6B
trafficking protein particle complex 6B
chr16_-_3350614 0.08 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr2_-_201753859 0.08 ENST00000409361.1
ENST00000392283.4
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr5_+_174151536 0.08 ENST00000239243.6
ENST00000507785.1
MSX2
msh homeobox 2
chr9_+_20927764 0.08 ENST00000603044.1
ENST00000604254.1
FOCAD
focadhesin
chr9_-_115095229 0.08 ENST00000210227.4
PTBP3
polypyrimidine tract binding protein 3
chr19_+_36606354 0.08 ENST00000589996.1
ENST00000591296.1
TBCB
tubulin folding cofactor B
chr19_-_22018966 0.08 ENST00000599906.1
ENST00000354959.4
ZNF43
zinc finger protein 43
chr12_-_118628315 0.08 ENST00000540561.1
TAOK3
TAO kinase 3
chr14_-_23426231 0.08 ENST00000556915.1
HAUS4
HAUS augmin-like complex, subunit 4
chrX_-_9734004 0.08 ENST00000467482.1
ENST00000380929.2
GPR143
G protein-coupled receptor 143
chr2_+_68592305 0.08 ENST00000234313.7
PLEK
pleckstrin
chr12_-_8088773 0.08 ENST00000544291.1
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr14_+_57671888 0.08 ENST00000391612.1
AL391152.1
AL391152.1
chr12_-_10282742 0.08 ENST00000298523.5
ENST00000396484.2
ENST00000310002.4
CLEC7A
C-type lectin domain family 7, member A
chr10_-_101825151 0.08 ENST00000441382.1
CPN1
carboxypeptidase N, polypeptide 1
chr7_+_30589829 0.08 ENST00000579437.1
RP4-777O23.1
RP4-777O23.1
chr2_-_201753717 0.08 ENST00000409264.2
PPIL3
peptidylprolyl isomerase (cyclophilin)-like 3
chr14_+_31046959 0.07 ENST00000547532.1
ENST00000555429.1
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chr3_+_136649311 0.07 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr4_-_146261573 0.07 ENST00000610239.1
RP11-142A22.4
RP11-142A22.4
chr18_+_46065393 0.07 ENST00000256413.3
CTIF
CBP80/20-dependent translation initiation factor
chr3_+_111718173 0.07 ENST00000494932.1
TAGLN3
transgelin 3
chr12_-_8088871 0.07 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr9_+_130911723 0.07 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr6_+_53964336 0.07 ENST00000447836.2
ENST00000511678.1
MLIP
muscular LMNA-interacting protein
chr4_-_39979576 0.07 ENST00000303538.8
ENST00000503396.1
PDS5A
PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)
chr2_+_228736335 0.07 ENST00000440997.1
ENST00000545118.1
DAW1
dynein assembly factor with WDR repeat domains 1
chr6_+_131958436 0.07 ENST00000357639.3
ENST00000543135.1
ENST00000427148.2
ENST00000358229.5
ENPP3
ectonucleotide pyrophosphatase/phosphodiesterase 3
chr19_+_9203855 0.07 ENST00000429566.3
OR1M1
olfactory receptor, family 1, subfamily M, member 1
chr11_+_110001723 0.07 ENST00000528673.1
ZC3H12C
zinc finger CCCH-type containing 12C
chr10_+_57358750 0.07 ENST00000512524.2
MTRNR2L5
MT-RNR2-like 5
chr18_-_67624160 0.07 ENST00000581982.1
ENST00000280200.4
CD226
CD226 molecule
chr19_+_50016411 0.07 ENST00000426395.3
ENST00000600273.1
ENST00000599988.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr3_-_143567262 0.07 ENST00000474151.1
ENST00000316549.6
SLC9A9
solute carrier family 9, subfamily A (NHE9, cation proton antiporter 9), member 9
chr1_-_159832438 0.07 ENST00000368100.1
VSIG8
V-set and immunoglobulin domain containing 8
chr18_+_55888767 0.07 ENST00000431212.2
ENST00000586268.1
ENST00000587190.1
NEDD4L
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr17_+_73539339 0.07 ENST00000581713.1
LLGL2
lethal giant larvae homolog 2 (Drosophila)
chr5_+_44809027 0.07 ENST00000507110.1
MRPS30
mitochondrial ribosomal protein S30
chr1_+_43613612 0.07 ENST00000335282.4
FAM183A
family with sequence similarity 183, member A
chr2_+_113816215 0.07 ENST00000346807.3
IL36RN
interleukin 36 receptor antagonist
chr12_-_14924056 0.07 ENST00000539745.1
HIST4H4
histone cluster 4, H4
chr15_-_44969022 0.06 ENST00000560110.1
PATL2
protein associated with topoisomerase II homolog 2 (yeast)
chr5_+_179135246 0.06 ENST00000508787.1
CANX
calnexin
chr14_+_39583427 0.06 ENST00000308317.6
ENST00000396249.2
ENST00000250379.8
ENST00000534684.2
ENST00000527381.1
GEMIN2
gem (nuclear organelle) associated protein 2
chr1_-_160924589 0.06 ENST00000368029.3
ITLN2
intelectin 2
chr16_+_15489629 0.06 ENST00000396385.3
MPV17L
MPV17 mitochondrial membrane protein-like
chr3_+_108541545 0.06 ENST00000295756.6
TRAT1
T cell receptor associated transmembrane adaptor 1
chr8_-_623547 0.06 ENST00000522893.1
ERICH1
glutamate-rich 1
chr19_+_11071546 0.06 ENST00000358026.2
SMARCA4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4

Network of associatons between targets according to the STRING database.

First level regulatory network of DLX1_HOXA3_BARX2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.3 GO:2001190 positive regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001190)
0.1 0.4 GO:0052027 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.1 0.3 GO:0035937 estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864)
0.1 0.3 GO:0010900 negative regulation of phosphatidylcholine catabolic process(GO:0010900)
0.1 0.2 GO:0002416 IgG immunoglobulin transcytosis in epithelial cells mediated by FcRn immunoglobulin receptor(GO:0002416)
0.1 0.6 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.2 GO:0072684 mitochondrial tRNA 3'-trailer cleavage, endonucleolytic(GO:0072684)
0.0 0.3 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.0 0.0 GO:2000625 regulation of miRNA catabolic process(GO:2000625) positive regulation of miRNA catabolic process(GO:2000627)
0.0 0.1 GO:0043105 regulation of GTP cyclohydrolase I activity(GO:0043095) negative regulation of GTP cyclohydrolase I activity(GO:0043105)
0.0 0.1 GO:1902714 negative regulation of interferon-gamma secretion(GO:1902714)
0.0 0.1 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.2 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0000294 nuclear-transcribed mRNA catabolic process, endonucleolytic cleavage-dependent decay(GO:0000294)
0.0 0.0 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:0051795 positive regulation of catagen(GO:0051795) activation of meiosis(GO:0090427)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:1903674 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.0 0.2 GO:0009212 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212)
0.0 0.1 GO:0030505 inorganic diphosphate transport(GO:0030505)
0.0 0.1 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.0 0.1 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.0 GO:0050777 negative regulation of immune response(GO:0050777)
0.0 0.3 GO:0070072 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0030807 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.2 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0038183 bile acid signaling pathway(GO:0038183)
0.0 0.1 GO:0018315 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.0 GO:0030522 intracellular receptor signaling pathway(GO:0030522)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.1 GO:0042441 eye pigment biosynthetic process(GO:0006726) eye pigment metabolic process(GO:0042441) pigment metabolic process involved in developmental pigmentation(GO:0043324) pigment metabolic process involved in pigmentation(GO:0043474)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:1904879 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.0 GO:0097187 dentinogenesis(GO:0097187) regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.0 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.1 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.0 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.0 0.2 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0033625 positive regulation of integrin activation(GO:0033625)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.0 GO:0043438 acetoacetic acid metabolic process(GO:0043438)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 1.2 GO:0042795 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0031302 intrinsic component of endosome membrane(GO:0031302)
0.0 0.4 GO:0072687 meiotic spindle(GO:0072687)
0.0 1.0 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.1 GO:0036028 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 0.3 GO:0042627 chylomicron(GO:0042627)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 1.0 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0044549 GTP cyclohydrolase binding(GO:0044549)
0.0 0.3 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.2 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.0 0.2 GO:0042781 3'-tRNA processing endoribonuclease activity(GO:0042781)
0.0 0.1 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.0 0.1 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.0 0.1 GO:0052829 inositol-1,4-bisphosphate 1-phosphatase activity(GO:0004441) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829)
0.0 0.1 GO:0035643 L-DOPA receptor activity(GO:0035643) L-DOPA binding(GO:0072544)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.0 0.1 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.0 0.1 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.2 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.0 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.0 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.0 GO:1904854 proteasome core complex binding(GO:1904854)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 0.0 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.0 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0 0.5 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi