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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for DBP

Z-value: 1.02

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Transcription factors associated with DBP

Gene Symbol Gene ID Gene Info
DBP
ENSG00000105516.6 D-box binding PAR bZIP transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
DBPhg19_v2_chr19_-_49140692_491407090.612.0e-01Click!

Activity profile of DBP motif

Sorted Z-values of DBP motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr21_+_17791648 1.14 ENST00000602892.1
ENST00000418813.2
ENST00000435697.1
LINC00478
long intergenic non-protein coding RNA 478
chr4_-_23891693 0.81 ENST00000264867.2
PPARGC1A
peroxisome proliferator-activated receptor gamma, coactivator 1 alpha
chr17_+_26833250 0.71 ENST00000577936.1
ENST00000579795.1
FOXN1
forkhead box N1
chr8_-_72268721 0.40 ENST00000419131.1
ENST00000388743.2
EYA1
eyes absent homolog 1 (Drosophila)
chr13_+_97874574 0.39 ENST00000343600.4
ENST00000345429.6
ENST00000376673.3
MBNL2
muscleblind-like splicing regulator 2
chr16_-_79634595 0.38 ENST00000326043.4
ENST00000393350.1
MAF
v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
chr2_-_164592497 0.38 ENST00000333129.3
ENST00000409634.1
FIGN
fidgetin
chr1_-_108231101 0.38 ENST00000544443.1
ENST00000415432.2
VAV3
vav 3 guanine nucleotide exchange factor
chr17_-_8263538 0.38 ENST00000535173.1
AC135178.1
HCG1985372; Uncharacterized protein; cDNA FLJ37541 fis, clone BRCAN2026340
chr8_+_86999516 0.38 ENST00000521564.1
ATP6V0D2
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d2
chr13_-_41593425 0.36 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr17_+_67498396 0.36 ENST00000588110.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr4_-_184243561 0.36 ENST00000514470.1
ENST00000541814.1
CLDN24
claudin 24
chr21_+_17791838 0.32 ENST00000453910.1
LINC00478
long intergenic non-protein coding RNA 478
chr13_+_97928395 0.31 ENST00000445661.2
MBNL2
muscleblind-like splicing regulator 2
chr11_-_47206965 0.30 ENST00000525725.1
PACSIN3
protein kinase C and casein kinase substrate in neurons 3
chr11_+_394145 0.29 ENST00000528036.1
PKP3
plakophilin 3
chr1_-_40367668 0.29 ENST00000397332.2
ENST00000429311.1
MYCL
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chrX_-_83442915 0.29 ENST00000262752.2
ENST00000543399.1
RPS6KA6
ribosomal protein S6 kinase, 90kDa, polypeptide 6
chr9_+_2017063 0.29 ENST00000457226.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr14_-_73360796 0.27 ENST00000556509.1
ENST00000541685.1
ENST00000546183.1
DPF3
D4, zinc and double PHD fingers, family 3
chr8_+_134125727 0.27 ENST00000521107.1
TG
thyroglobulin
chr9_+_2158443 0.27 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr1_+_61547405 0.27 ENST00000371189.4
NFIA
nuclear factor I/A
chr6_-_31514516 0.26 ENST00000303892.5
ENST00000483251.1
ATP6V1G2
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2
chr10_-_81203972 0.26 ENST00000372333.3
ZCCHC24
zinc finger, CCHC domain containing 24
chr14_-_23652849 0.26 ENST00000316902.7
ENST00000469263.1
ENST00000525062.1
ENST00000524758.1
SLC7A8
solute carrier family 7 (amino acid transporter light chain, L system), member 8
chr22_-_31742218 0.26 ENST00000266269.5
ENST00000405309.3
ENST00000351933.4
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr6_+_90272488 0.26 ENST00000485637.1
ENST00000522705.1
ANKRD6
ankyrin repeat domain 6
chr8_-_102803163 0.25 ENST00000523645.1
ENST00000520346.1
ENST00000220931.6
ENST00000522448.1
ENST00000522951.1
ENST00000522252.1
ENST00000519098.1
NCALD
neurocalcin delta
chr9_+_2158485 0.25 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr11_+_121461097 0.24 ENST00000527934.1
SORL1
sortilin-related receptor, L(DLR class) A repeats containing
chrX_+_28605516 0.24 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr6_+_26045603 0.24 ENST00000540144.1
HIST1H3C
histone cluster 1, H3c
chrX_+_10031499 0.23 ENST00000454666.1
WWC3
WWC family member 3
chr4_-_100242549 0.22 ENST00000305046.8
ENST00000394887.3
ADH1B
alcohol dehydrogenase 1B (class I), beta polypeptide
chrX_-_111923145 0.22 ENST00000371968.3
ENST00000536453.1
LHFPL1
lipoma HMGIC fusion partner-like 1
chr18_-_25616519 0.22 ENST00000399380.3
CDH2
cadherin 2, type 1, N-cadherin (neuronal)
chr20_-_14318248 0.22 ENST00000378053.3
ENST00000341420.4
FLRT3
fibronectin leucine rich transmembrane protein 3
chr1_+_206623784 0.21 ENST00000426388.1
SRGAP2
SLIT-ROBO Rho GTPase activating protein 2
chr8_-_22550815 0.21 ENST00000317216.2
EGR3
early growth response 3
chr12_-_92536433 0.21 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79
chromosome 12 open reading frame 79
chr16_+_30960375 0.20 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3
ORAI calcium release-activated calcium modulator 3
chr17_+_42429493 0.20 ENST00000586242.1
GRN
granulin
chr8_-_17533838 0.20 ENST00000400046.1
MTUS1
microtubule associated tumor suppressor 1
chr3_-_33700589 0.20 ENST00000461133.3
ENST00000496954.2
CLASP2
cytoplasmic linker associated protein 2
chr6_-_18122843 0.20 ENST00000340650.3
NHLRC1
NHL repeat containing E3 ubiquitin protein ligase 1
chr1_+_12538594 0.19 ENST00000543710.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr3_-_171489085 0.19 ENST00000418087.1
PLD1
phospholipase D1, phosphatidylcholine-specific
chr10_-_79397202 0.18 ENST00000372437.1
ENST00000372408.2
ENST00000372403.4
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chrX_-_10851762 0.18 ENST00000380785.1
ENST00000380787.1
MID1
midline 1 (Opitz/BBB syndrome)
chr5_+_50679506 0.18 ENST00000511384.1
ISL1
ISL LIM homeobox 1
chr12_+_18891045 0.18 ENST00000317658.3
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr1_-_151148442 0.18 ENST00000441701.1
ENST00000416280.2
TMOD4
tropomodulin 4 (muscle)
chrX_+_134654540 0.18 ENST00000370752.4
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chrX_+_153769446 0.18 ENST00000422680.1
IKBKG
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
chr4_+_24797085 0.18 ENST00000382120.3
SOD3
superoxide dismutase 3, extracellular
chr19_+_41856816 0.17 ENST00000539627.1
TMEM91
transmembrane protein 91
chr1_-_40367530 0.17 ENST00000372816.2
ENST00000372815.1
MYCL
v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog
chrX_-_151619746 0.17 ENST00000370314.4
GABRA3
gamma-aminobutyric acid (GABA) A receptor, alpha 3
chr16_+_86612112 0.17 ENST00000320241.3
FOXL1
forkhead box L1
chr1_+_229440129 0.16 ENST00000366688.3
SPHAR
S-phase response (cyclin related)
chr11_-_16403910 0.16 ENST00000526673.1
SOX6
SRY (sex determining region Y)-box 6
chr11_+_34999328 0.16 ENST00000526309.1
PDHX
pyruvate dehydrogenase complex, component X
chr2_-_174830430 0.16 ENST00000310015.6
ENST00000455789.2
SP3
Sp3 transcription factor
chr6_-_75953484 0.15 ENST00000472311.2
ENST00000460985.1
ENST00000377978.3
ENST00000509698.1
ENST00000230459.4
ENST00000370089.2
COX7A2
cytochrome c oxidase subunit VIIa polypeptide 2 (liver)
chr2_+_234602305 0.15 ENST00000406651.1
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr5_+_180467259 0.15 ENST00000515271.1
BTNL9
butyrophilin-like 9
chr2_+_29001711 0.15 ENST00000418910.1
PPP1CB
protein phosphatase 1, catalytic subunit, beta isozyme
chr4_-_186732048 0.15 ENST00000448662.2
ENST00000439049.1
ENST00000420158.1
ENST00000431808.1
ENST00000319471.9
SORBS2
sorbin and SH3 domain containing 2
chr5_+_32710736 0.14 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr14_+_45366518 0.14 ENST00000557112.1
C14orf28
chromosome 14 open reading frame 28
chr10_-_79397316 0.14 ENST00000372421.5
ENST00000457953.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chrX_+_49832231 0.14 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr6_+_45296391 0.14 ENST00000371436.6
ENST00000576263.1
RUNX2
runt-related transcription factor 2
chr3_+_153202284 0.14 ENST00000446603.2
C3orf79
chromosome 3 open reading frame 79
chr20_+_9146969 0.14 ENST00000416836.1
PLCB4
phospholipase C, beta 4
chr10_-_79397391 0.14 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr1_+_104104379 0.14 ENST00000435302.1
AMY2B
amylase, alpha 2B (pancreatic)
chr3_+_190333097 0.13 ENST00000412080.1
IL1RAP
interleukin 1 receptor accessory protein
chrX_+_149531524 0.13 ENST00000370401.2
MAMLD1
mastermind-like domain containing 1
chr12_-_62586543 0.13 ENST00000416284.3
FAM19A2
family with sequence similarity 19 (chemokine (C-C motif)-like), member A2
chr7_+_127233689 0.13 ENST00000265825.5
ENST00000420086.2
FSCN3
fascin homolog 3, actin-bundling protein, testicular (Strongylocentrotus purpuratus)
chr4_-_87281196 0.13 ENST00000359221.3
MAPK10
mitogen-activated protein kinase 10
chr16_+_30675654 0.13 ENST00000287468.5
ENST00000395073.2
FBRS
fibrosin
chr17_+_67498538 0.13 ENST00000589647.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr18_-_21891460 0.12 ENST00000357041.4
OSBPL1A
oxysterol binding protein-like 1A
chr10_+_115511434 0.12 ENST00000369312.4
PLEKHS1
pleckstrin homology domain containing, family S member 1
chr19_-_41220957 0.12 ENST00000596357.1
ENST00000243583.6
ENST00000600080.1
ENST00000595254.1
ENST00000601967.1
ADCK4
aarF domain containing kinase 4
chr6_-_56819385 0.12 ENST00000370754.5
ENST00000449297.2
DST
dystonin
chr19_+_13135386 0.12 ENST00000360105.4
ENST00000588228.1
ENST00000591028.1
NFIX
nuclear factor I/X (CCAAT-binding transcription factor)
chr14_-_23479331 0.12 ENST00000397377.1
ENST00000397379.3
ENST00000406429.2
ENST00000341470.4
ENST00000555998.1
ENST00000397376.2
ENST00000553675.1
ENST00000553931.1
ENST00000555575.1
ENST00000553958.1
ENST00000555098.1
ENST00000556419.1
ENST00000553606.1
ENST00000299088.6
ENST00000554179.1
ENST00000397382.4
C14orf93
chromosome 14 open reading frame 93
chr17_+_72426891 0.12 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr11_+_394196 0.12 ENST00000331563.2
ENST00000531857.1
PKP3
plakophilin 3
chr1_+_87797351 0.12 ENST00000370542.1
LMO4
LIM domain only 4
chr1_+_202385953 0.12 ENST00000466968.1
PPP1R12B
protein phosphatase 1, regulatory subunit 12B
chr12_-_6483969 0.12 ENST00000396966.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chrX_+_149531606 0.11 ENST00000432680.2
MAMLD1
mastermind-like domain containing 1
chrX_+_16141667 0.11 ENST00000380289.2
GRPR
gastrin-releasing peptide receptor
chr6_-_42419649 0.11 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1
transcriptional regulating factor 1
chr5_-_111091948 0.11 ENST00000447165.2
NREP
neuronal regeneration related protein
chr8_-_6420759 0.11 ENST00000523120.1
ANGPT2
angiopoietin 2
chr8_-_22549856 0.11 ENST00000522910.1
EGR3
early growth response 3
chr2_+_191002486 0.11 ENST00000396974.2
C2orf88
chromosome 2 open reading frame 88
chr18_+_61223393 0.11 ENST00000269491.1
ENST00000382768.1
SERPINB12
serpin peptidase inhibitor, clade B (ovalbumin), member 12
chr10_+_115511213 0.11 ENST00000361048.1
PLEKHS1
pleckstrin homology domain containing, family S member 1
chrX_+_49644470 0.11 ENST00000508866.2
USP27X
ubiquitin specific peptidase 27, X-linked
chr1_+_162039558 0.11 ENST00000530878.1
ENST00000361897.5
NOS1AP
nitric oxide synthase 1 (neuronal) adaptor protein
chr2_+_234601512 0.11 ENST00000305139.6
UGT1A6
UDP glucuronosyltransferase 1 family, polypeptide A6
chr9_+_139886846 0.11 ENST00000371620.3
C9orf142
chromosome 9 open reading frame 142
chr17_-_34308524 0.11 ENST00000293275.3
CCL16
chemokine (C-C motif) ligand 16
chr12_+_65218352 0.11 ENST00000539867.1
ENST00000544457.1
ENST00000539120.1
TBC1D30
TBC1 domain family, member 30
chr2_+_166326157 0.10 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr2_+_166430619 0.10 ENST00000409420.1
CSRNP3
cysteine-serine-rich nuclear protein 3
chr12_-_120765565 0.10 ENST00000423423.3
ENST00000308366.4
PLA2G1B
phospholipase A2, group IB (pancreas)
chrX_+_56590002 0.10 ENST00000338222.5
UBQLN2
ubiquilin 2
chr13_+_44947941 0.10 ENST00000379179.3
SERP2
stress-associated endoplasmic reticulum protein family member 2
chr9_+_72658490 0.10 ENST00000377182.4
MAMDC2
MAM domain containing 2
chr10_-_31288398 0.10 ENST00000538351.2
ZNF438
zinc finger protein 438
chr20_+_18447771 0.10 ENST00000377603.4
POLR3F
polymerase (RNA) III (DNA directed) polypeptide F, 39 kDa
chr1_+_24645807 0.10 ENST00000361548.4
GRHL3
grainyhead-like 3 (Drosophila)
chr1_-_238108575 0.10 ENST00000604646.1
MTRNR2L11
MT-RNR2-like 11 (pseudogene)
chr1_+_24645865 0.10 ENST00000342072.4
GRHL3
grainyhead-like 3 (Drosophila)
chr10_-_99052382 0.10 ENST00000453547.2
ENST00000316676.8
ENST00000358308.3
ENST00000466484.1
ENST00000358531.4
ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 readthrough (NMD candidate)
Rho GTPase activating protein 19
chr14_-_36988882 0.10 ENST00000498187.2
NKX2-1
NK2 homeobox 1
chr4_-_87281224 0.09 ENST00000395169.3
ENST00000395161.2
MAPK10
mitogen-activated protein kinase 10
chr4_+_106473768 0.09 ENST00000265154.2
ENST00000420470.2
ARHGEF38
Rho guanine nucleotide exchange factor (GEF) 38
chr14_+_93357749 0.09 ENST00000557689.1
RP11-862G15.1
RP11-862G15.1
chr3_-_112564797 0.09 ENST00000398214.1
ENST00000448932.1
CD200R1L
CD200 receptor 1-like
chr17_-_48546324 0.09 ENST00000508540.1
CHAD
chondroadherin
chr10_-_79397479 0.09 ENST00000404771.3
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr10_+_21823243 0.09 ENST00000307729.7
ENST00000377091.2
MLLT10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chrX_+_129473859 0.09 ENST00000424447.1
SLC25A14
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr10_-_64576105 0.09 ENST00000242480.3
ENST00000411732.1
EGR2
early growth response 2
chr17_+_48823896 0.09 ENST00000511974.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr1_+_24645915 0.09 ENST00000350501.5
GRHL3
grainyhead-like 3 (Drosophila)
chr17_-_56492989 0.09 ENST00000583753.1
RNF43
ring finger protein 43
chr7_+_13141097 0.09 ENST00000411542.1
AC011288.2
AC011288.2
chr3_-_52479043 0.08 ENST00000231721.2
ENST00000475739.1
SEMA3G
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr1_+_24646002 0.08 ENST00000356046.2
GRHL3
grainyhead-like 3 (Drosophila)
chr18_+_52385068 0.08 ENST00000586570.1
RAB27B
RAB27B, member RAS oncogene family
chr5_-_124080203 0.08 ENST00000504926.1
ZNF608
zinc finger protein 608
chr8_-_101718991 0.08 ENST00000517990.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr17_+_48624450 0.08 ENST00000006658.6
ENST00000356488.4
ENST00000393244.3
SPATA20
spermatogenesis associated 20
chr22_+_45714361 0.08 ENST00000452238.1
FAM118A
family with sequence similarity 118, member A
chr1_-_85870177 0.08 ENST00000542148.1
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr5_+_67576062 0.08 ENST00000523807.1
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr4_-_76555657 0.08 ENST00000307465.4
CDKL2
cyclin-dependent kinase-like 2 (CDC2-related kinase)
chr1_+_61548225 0.08 ENST00000371187.3
NFIA
nuclear factor I/A
chr7_-_150946015 0.08 ENST00000262188.8
SMARCD3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr8_+_107738240 0.08 ENST00000449762.2
ENST00000297447.6
OXR1
oxidation resistance 1
chr10_+_104178946 0.08 ENST00000432590.1
FBXL15
F-box and leucine-rich repeat protein 15
chr1_+_84609944 0.08 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr9_+_35829208 0.08 ENST00000439587.2
ENST00000377991.4
TMEM8B
transmembrane protein 8B
chr20_+_11898507 0.08 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr19_+_39881951 0.07 ENST00000315588.5
ENST00000594368.1
ENST00000599213.2
ENST00000596297.1
MED29
mediator complex subunit 29
chr1_-_23886285 0.07 ENST00000374561.5
ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr17_+_28705921 0.07 ENST00000225719.4
CPD
carboxypeptidase D
chr1_+_203734296 0.07 ENST00000442561.2
ENST00000367217.5
LAX1
lymphocyte transmembrane adaptor 1
chr7_+_26331678 0.07 ENST00000446848.2
SNX10
sorting nexin 10
chr3_-_48471454 0.07 ENST00000296440.6
ENST00000448774.2
PLXNB1
plexin B1
chr8_-_22550691 0.07 ENST00000519492.1
EGR3
early growth response 3
chrX_+_49028265 0.07 ENST00000376322.3
ENST00000376327.5
PLP2
proteolipid protein 2 (colonic epithelium-enriched)
chr17_-_48546232 0.07 ENST00000258969.4
CHAD
chondroadherin
chr2_-_211036051 0.07 ENST00000418791.1
ENST00000452086.1
ENST00000281772.9
KANSL1L
KAT8 regulatory NSL complex subunit 1-like
chr12_-_99548524 0.07 ENST00000549558.2
ENST00000550693.2
ENST00000549493.2
ANKS1B
ankyrin repeat and sterile alpha motif domain containing 1B
chr4_-_89978299 0.07 ENST00000511976.1
ENST00000509094.1
ENST00000264344.5
ENST00000515600.1
FAM13A
family with sequence similarity 13, member A
chr2_-_111291587 0.07 ENST00000437167.1
RGPD6
RANBP2-like and GRIP domain containing 6
chr14_+_32963433 0.07 ENST00000554410.1
AKAP6
A kinase (PRKA) anchor protein 6
chr1_+_27648709 0.07 ENST00000608611.1
ENST00000466759.1
ENST00000464813.1
ENST00000498220.1
TMEM222
transmembrane protein 222
chr3_-_50541028 0.07 ENST00000266039.3
ENST00000435965.1
ENST00000395083.1
CACNA2D2
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr11_-_62414070 0.06 ENST00000540933.1
ENST00000346178.4
ENST00000356638.3
ENST00000534779.1
ENST00000525994.1
GANAB
glucosidase, alpha; neutral AB
chrX_-_54070607 0.06 ENST00000338154.6
ENST00000338946.6
PHF8
PHD finger protein 8
chr14_-_37051798 0.06 ENST00000258829.5
NKX2-8
NK2 homeobox 8
chr17_+_67498295 0.06 ENST00000589295.1
MAP2K6
mitogen-activated protein kinase kinase 6
chr2_+_210444748 0.06 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr1_+_211433275 0.06 ENST00000367005.4
RCOR3
REST corepressor 3
chr1_+_24646263 0.06 ENST00000524724.1
GRHL3
grainyhead-like 3 (Drosophila)
chr13_+_93879085 0.06 ENST00000377047.4
GPC6
glypican 6
chr16_-_18468926 0.06 ENST00000545114.1
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr12_-_18890940 0.06 ENST00000543242.1
ENST00000539072.1
ENST00000541966.1
ENST00000266505.7
ENST00000447925.2
ENST00000435379.1
PLCZ1
phospholipase C, zeta 1
chr18_-_2982869 0.06 ENST00000584915.1
LPIN2
lipin 2
chr2_+_168725458 0.06 ENST00000392690.3
B3GALT1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr8_+_107738343 0.06 ENST00000521592.1
OXR1
oxidation resistance 1
chr6_-_134499037 0.06 ENST00000528577.1
SGK1
serum/glucocorticoid regulated kinase 1
chr4_-_186732241 0.06 ENST00000421639.1
SORBS2
sorbin and SH3 domain containing 2
chr6_-_33168391 0.06 ENST00000374685.4
ENST00000413614.2
ENST00000374680.3
RXRB
retinoid X receptor, beta
chr2_-_21266816 0.06 ENST00000399256.4
APOB
apolipoprotein B
chr16_-_75282088 0.06 ENST00000542031.2
BCAR1
breast cancer anti-estrogen resistance 1
chr16_+_89724188 0.06 ENST00000301031.4
ENST00000566204.1
ENST00000579310.1
SPATA33
spermatogenesis associated 33
chr1_+_104293028 0.06 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr17_+_48823975 0.05 ENST00000513969.1
ENST00000503728.1
LUC7L3
LUC7-like 3 (S. cerevisiae)
chr11_+_102980251 0.05 ENST00000334267.7
ENST00000398093.3
DYNC2H1
dynein, cytoplasmic 2, heavy chain 1
chr11_-_7950209 0.05 ENST00000309838.2
OR10A6
olfactory receptor, family 10, subfamily A, member 6
chr5_+_149877440 0.05 ENST00000518299.1
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr10_-_29811456 0.05 ENST00000535393.1
SVIL
supervillin
chr8_-_114449112 0.05 ENST00000455883.2
ENST00000352409.3
ENST00000297405.5
CSMD3
CUB and Sushi multiple domains 3
chrY_+_4868267 0.05 ENST00000333703.4
PCDH11Y
protocadherin 11 Y-linked
chr12_-_88423164 0.05 ENST00000298699.2
ENST00000550553.1
C12orf50
chromosome 12 open reading frame 50
chr8_+_16884740 0.05 ENST00000318063.5
MICU3
mitochondrial calcium uptake family, member 3

Network of associatons between targets according to the STRING database.

First level regulatory network of DBP

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878) positive regulation of mitochondrial DNA metabolic process(GO:1901860) response to methionine(GO:1904640)
0.2 0.7 GO:0097534 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535) regulation of positive thymic T cell selection(GO:1902232)
0.1 0.6 GO:0072709 cellular response to sorbitol(GO:0072709)
0.1 0.2 GO:1902960 regulation of choline O-acetyltransferase activity(GO:1902769) positive regulation of choline O-acetyltransferase activity(GO:1902771) negative regulation of tau-protein kinase activity(GO:1902948) positive regulation of early endosome to recycling endosome transport(GO:1902955) negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902960) negative regulation of neurofibrillary tangle assembly(GO:1902997) negative regulation of aspartic-type peptidase activity(GO:1905246)
0.1 0.5 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.2 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524) cardiac cell fate determination(GO:0060913)
0.0 0.6 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.4 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.4 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.4 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586)
0.0 0.3 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.1 GO:1905033 positive regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903762) positive regulation of ventricular cardiac muscle cell action potential(GO:1903947) positive regulation of membrane repolarization during ventricular cardiac muscle cell action potential(GO:1905026) positive regulation of membrane repolarization during cardiac muscle cell action potential(GO:1905033)
0.0 0.1 GO:1904020 regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.2 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0021778 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0035283 rhombomere 3 development(GO:0021569) rhombomere 5 development(GO:0021571) central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0 0.1 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.0 0.2 GO:2000809 positive regulation of synaptic vesicle clustering(GO:2000809)
0.0 0.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.1 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.2 GO:0003344 pericardium morphogenesis(GO:0003344)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0036371 protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.3 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.4 GO:0090179 planar cell polarity pathway involved in neural tube closure(GO:0090179)
0.0 0.1 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.7 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.2 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.0 GO:1904693 midbrain morphogenesis(GO:1904693)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.1 GO:0034371 chylomicron remodeling(GO:0034371)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.3 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.0 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.0 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103) positive regulation of interleukin-6-mediated signaling pathway(GO:0070105)
0.0 0.2 GO:0061430 bone trabecula formation(GO:0060346) bone trabecula morphogenesis(GO:0061430)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.0 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 GO:0071565 nBAF complex(GO:0071565)
0.0 0.8 GO:0097440 apical dendrite(GO:0097440)
0.0 0.7 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 1.0 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0050115 myosin-light-chain-phosphatase activity(GO:0050115)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0019534 toxin transporter activity(GO:0019534)
0.0 0.2 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.2 GO:0034603 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.2 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0016403 dimethylargininase activity(GO:0016403)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.9 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.7 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation