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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CXXC1

Z-value: 1.77

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Transcription factors associated with CXXC1

Gene Symbol Gene ID Gene Info
CXXC1
ENSG00000154832.10 CXXC finger protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CXXC1hg19_v2_chr18_-_47813940_47814021-0.285.9e-01Click!

Activity profile of CXXC1 motif

Sorted Z-values of CXXC1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_183989157 1.39 ENST00000541912.1
NUP35
nucleoporin 35kDa
chr2_+_67624430 1.08 ENST00000272342.5
ETAA1
Ewing tumor-associated antigen 1
chr15_+_63414760 0.84 ENST00000557972.1
LACTB
lactamase, beta
chr3_-_150264272 0.82 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr4_+_187112674 0.81 ENST00000378802.4
CYP4V2
cytochrome P450, family 4, subfamily V, polypeptide 2
chr15_+_55611128 0.80 ENST00000164305.5
ENST00000539642.1
PIGB
phosphatidylinositol glycan anchor biosynthesis, class B
chr2_+_183989083 0.79 ENST00000295119.4
NUP35
nucleoporin 35kDa
chr6_-_113953705 0.76 ENST00000452675.1
RP11-367G18.1
RP11-367G18.1
chr2_+_9563769 0.75 ENST00000475482.1
CPSF3
cleavage and polyadenylation specific factor 3, 73kDa
chr3_+_178865887 0.75 ENST00000477735.1
PIK3CA
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha
chr14_-_53258180 0.74 ENST00000554230.1
GNPNAT1
glucosamine-phosphate N-acetyltransferase 1
chr1_+_40723779 0.73 ENST00000372759.3
ZMPSTE24
zinc metallopeptidase STE24
chr5_+_68485433 0.73 ENST00000502689.1
CENPH
centromere protein H
chr17_+_5390220 0.72 ENST00000381165.3
MIS12
MIS12 kinetochore complex component
chr8_-_71520513 0.69 ENST00000262213.2
ENST00000536748.1
ENST00000518678.1
TRAM1
translocation associated membrane protein 1
chr13_-_33112823 0.68 ENST00000504114.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr5_+_68485363 0.67 ENST00000283006.2
ENST00000515001.1
CENPH
centromere protein H
chr14_-_81687197 0.65 ENST00000553612.1
GTF2A1
general transcription factor IIA, 1, 19/37kDa
chr2_+_201390843 0.65 ENST00000357799.4
ENST00000409203.3
SGOL2
shugoshin-like 2 (S. pombe)
chr16_-_66864806 0.64 ENST00000566336.1
ENST00000394074.2
ENST00000563185.2
ENST00000359087.4
ENST00000379463.2
ENST00000565535.1
ENST00000290810.3
NAE1
NEDD8 activating enzyme E1 subunit 1
chr12_+_21654714 0.64 ENST00000542038.1
ENST00000540141.1
ENST00000229314.5
GOLT1B
golgi transport 1B
chr4_+_39460659 0.62 ENST00000513731.1
LIAS
lipoic acid synthetase
chr2_-_55920952 0.62 ENST00000447944.2
PNPT1
polyribonucleotide nucleotidyltransferase 1
chr20_+_52824367 0.62 ENST00000371419.2
PFDN4
prefoldin subunit 4
chr14_+_32546485 0.61 ENST00000345122.3
ENST00000432921.1
ENST00000433497.1
ARHGAP5
Rho GTPase activating protein 5
chr9_-_93727673 0.61 ENST00000427745.1
RP11-367F23.1
RP11-367F23.1
chr1_+_214776516 0.60 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chr19_-_5624057 0.59 ENST00000590262.1
SAFB2
scaffold attachment factor B2
chr5_-_82373260 0.59 ENST00000502346.1
TMEM167A
transmembrane protein 167A
chr19_-_43702231 0.58 ENST00000597374.1
ENST00000599371.1
PSG4
pregnancy specific beta-1-glycoprotein 4
chr4_+_25378912 0.58 ENST00000510092.1
ENST00000505991.1
ANAPC4
anaphase promoting complex subunit 4
chr1_-_244615425 0.58 ENST00000366535.3
ADSS
adenylosuccinate synthase
chr4_+_175205038 0.57 ENST00000457424.2
ENST00000514712.1
CEP44
centrosomal protein 44kDa
chr1_+_198126093 0.57 ENST00000367385.4
ENST00000442588.1
ENST00000538004.1
NEK7
NIMA-related kinase 7
chr17_+_5389605 0.57 ENST00000576988.1
ENST00000576570.1
ENST00000573759.1
MIS12
MIS12 kinetochore complex component
chr4_+_141294628 0.56 ENST00000512749.1
ENST00000608372.1
ENST00000506597.1
ENST00000394201.4
ENST00000510586.1
SCOC
short coiled-coil protein
chr1_-_63988846 0.55 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP
integrin beta 3 binding protein (beta3-endonexin)
chr13_-_21750659 0.55 ENST00000400018.3
ENST00000314759.5
SKA3
spindle and kinetochore associated complex subunit 3
chr5_+_115177178 0.54 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr20_+_5986727 0.54 ENST00000378863.4
CRLS1
cardiolipin synthase 1
chr1_+_10057274 0.53 ENST00000294435.7
RBP7
retinol binding protein 7, cellular
chr15_+_63682335 0.53 ENST00000559379.1
ENST00000559821.1
RP11-321G12.1
RP11-321G12.1
chr13_-_33112899 0.52 ENST00000267068.3
ENST00000357505.6
ENST00000399396.3
N4BP2L2
NEDD4 binding protein 2-like 2
chr10_+_89264625 0.52 ENST00000371996.4
ENST00000371994.4
MINPP1
multiple inositol-polyphosphate phosphatase 1
chr2_+_17997763 0.51 ENST00000281047.3
MSGN1
mesogenin 1
chr2_-_114514181 0.51 ENST00000409342.1
SLC35F5
solute carrier family 35, member F5
chr19_-_39360561 0.50 ENST00000593809.1
ENST00000593424.1
RINL
Ras and Rab interactor-like
chr19_-_51289374 0.50 ENST00000563228.1
CTD-2568A17.1
CTD-2568A17.1
chr8_-_90993869 0.50 ENST00000517772.1
NBN
nibrin
chr4_+_78829479 0.49 ENST00000504901.1
MRPL1
mitochondrial ribosomal protein L1
chr17_+_29421987 0.49 ENST00000431387.4
NF1
neurofibromin 1
chr1_+_63989004 0.49 ENST00000371088.4
EFCAB7
EF-hand calcium binding domain 7
chr9_+_131703757 0.48 ENST00000482796.1
RP11-101E3.5
RP11-101E3.5
chr5_+_41904431 0.48 ENST00000381647.2
C5orf51
chromosome 5 open reading frame 51
chr6_-_46703069 0.48 ENST00000538237.1
ENST00000274793.7
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr2_-_239148599 0.48 ENST00000409182.1
ENST00000409002.3
ENST00000450098.1
ENST00000409356.1
ENST00000409160.3
ENST00000409574.1
ENST00000272937.5
HES6
hes family bHLH transcription factor 6
chr11_+_64052294 0.48 ENST00000536667.1
GPR137
G protein-coupled receptor 137
chr12_-_42538480 0.48 ENST00000280876.6
GXYLT1
glucoside xylosyltransferase 1
chr2_-_152684977 0.48 ENST00000428992.2
ENST00000295087.8
ARL5A
ADP-ribosylation factor-like 5A
chr4_+_25378826 0.48 ENST00000315368.3
ANAPC4
anaphase promoting complex subunit 4
chr12_+_4430371 0.47 ENST00000179259.4
C12orf5
chromosome 12 open reading frame 5
chr17_+_29421900 0.47 ENST00000358273.4
ENST00000356175.3
NF1
neurofibromin 1
chr1_-_93426998 0.47 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr1_-_85156090 0.47 ENST00000605755.1
ENST00000437941.2
SSX2IP
synovial sarcoma, X breakpoint 2 interacting protein
chr1_-_67390474 0.46 ENST00000371023.3
ENST00000371022.3
ENST00000371026.3
ENST00000431318.1
WDR78
WD repeat domain 78
chr13_-_33112956 0.46 ENST00000505213.1
N4BP2L2
NEDD4 binding protein 2-like 2
chr19_-_22034770 0.46 ENST00000598381.1
ZNF43
zinc finger protein 43
chr17_-_56065540 0.46 ENST00000583932.1
VEZF1
vascular endothelial zinc finger 1
chr4_+_85504075 0.46 ENST00000295887.5
CDS1
CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1
chr19_-_23433144 0.46 ENST00000418100.1
ENST00000597537.1
ENST00000597037.1
ZNF724P
zinc finger protein 724, pseudogene
chr22_+_50925213 0.46 ENST00000395733.3
ENST00000216075.6
ENST00000395732.3
MIOX
myo-inositol oxygenase
chr1_-_114430169 0.45 ENST00000393316.3
BCL2L15
BCL2-like 15
chr1_-_211752073 0.45 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr3_-_122134882 0.45 ENST00000330689.4
WDR5B
WD repeat domain 5B
chr14_+_32546145 0.44 ENST00000556611.1
ENST00000539826.2
ARHGAP5
Rho GTPase activating protein 5
chr4_+_39460620 0.44 ENST00000340169.2
ENST00000261434.3
LIAS
lipoic acid synthetase
chr7_+_26241325 0.44 ENST00000456948.1
ENST00000409747.1
CBX3
chromobox homolog 3
chr10_-_79397547 0.43 ENST00000481070.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr19_-_40596767 0.43 ENST00000599972.1
ENST00000450241.2
ENST00000595687.2
ZNF780A
zinc finger protein 780A
chr17_+_39846114 0.43 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr14_-_24977457 0.43 ENST00000250378.3
ENST00000206446.4
CMA1
chymase 1, mast cell
chr2_-_152118352 0.42 ENST00000331426.5
RBM43
RNA binding motif protein 43
chr2_+_32390925 0.42 ENST00000440718.1
ENST00000379343.2
ENST00000282587.5
ENST00000435660.1
ENST00000538303.1
ENST00000357055.3
ENST00000406369.1
SLC30A6
solute carrier family 30 (zinc transporter), member 6
chr12_-_110906027 0.42 ENST00000537466.2
ENST00000550974.1
ENST00000228827.3
GPN3
GPN-loop GTPase 3
chr7_+_107220660 0.42 ENST00000465919.1
ENST00000445771.2
ENST00000479917.1
ENST00000421217.1
ENST00000457837.1
BCAP29
B-cell receptor-associated protein 29
chr2_-_55276320 0.42 ENST00000357376.3
RTN4
reticulon 4
chr5_-_37371278 0.42 ENST00000231498.3
NUP155
nucleoporin 155kDa
chr1_-_70671216 0.41 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr15_-_55611306 0.41 ENST00000563262.1
RAB27A
RAB27A, member RAS oncogene family
chr5_-_132202329 0.40 ENST00000378673.2
GDF9
growth differentiation factor 9
chr12_-_110883346 0.40 ENST00000547365.1
ARPC3
actin related protein 2/3 complex, subunit 3, 21kDa
chr6_+_126277842 0.40 ENST00000229633.5
HINT3
histidine triad nucleotide binding protein 3
chr1_-_231376867 0.40 ENST00000366649.2
ENST00000318906.2
ENST00000366651.3
C1orf131
chromosome 1 open reading frame 131
chr1_+_63833261 0.40 ENST00000371108.4
ALG6
ALG6, alpha-1,3-glucosyltransferase
chr18_+_44497455 0.40 ENST00000592005.1
KATNAL2
katanin p60 subunit A-like 2
chr18_+_2571510 0.40 ENST00000261597.4
ENST00000575515.1
NDC80
NDC80 kinetochore complex component
chr1_+_6845578 0.40 ENST00000467404.2
ENST00000439411.2
CAMTA1
calmodulin binding transcription activator 1
chr9_-_95055923 0.40 ENST00000430417.1
IARS
isoleucyl-tRNA synthetase
chrX_+_77166172 0.39 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A
ATPase, Cu++ transporting, alpha polypeptide
chr2_+_37423618 0.39 ENST00000402297.1
ENST00000397064.2
ENST00000406711.1
ENST00000392061.2
ENST00000397226.2
AC007390.5
CEBPZ antisense RNA 1
chr1_+_9005917 0.39 ENST00000549778.1
ENST00000480186.3
ENST00000377443.2
ENST00000377436.3
ENST00000377442.2
CA6
carbonic anhydrase VI
chr2_-_128145498 0.39 ENST00000409179.2
MAP3K2
mitogen-activated protein kinase kinase kinase 2
chr8_-_80993010 0.39 ENST00000537855.1
ENST00000520527.1
ENST00000517427.1
ENST00000448733.2
ENST00000379097.3
TPD52
tumor protein D52
chr1_+_222886694 0.39 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
BROX
BRO1 domain and CAAX motif containing
chr2_-_55277692 0.39 ENST00000394611.2
RTN4
reticulon 4
chr14_+_75536335 0.38 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr6_-_121655850 0.38 ENST00000422369.1
TBC1D32
TBC1 domain family, member 32
chrX_+_47077680 0.38 ENST00000522883.1
CDK16
cyclin-dependent kinase 16
chr20_+_5986756 0.38 ENST00000452938.1
CRLS1
cardiolipin synthase 1
chr17_-_39728303 0.38 ENST00000588431.1
ENST00000246662.4
KRT9
keratin 9
chr19_-_40562063 0.38 ENST00000598845.1
ENST00000593605.1
ENST00000221355.6
ENST00000434248.1
ZNF780B
zinc finger protein 780B
chr10_-_79397391 0.38 ENST00000286628.8
ENST00000406533.3
ENST00000354353.5
ENST00000404857.1
KCNMA1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr2_+_47596634 0.37 ENST00000419334.1
EPCAM
epithelial cell adhesion molecule
chr2_-_74648702 0.37 ENST00000518863.1
C2orf81
chromosome 2 open reading frame 81
chr7_+_23221438 0.37 ENST00000258742.5
NUPL2
nucleoporin like 2
chr3_+_23986748 0.37 ENST00000312521.4
NR1D2
nuclear receptor subfamily 1, group D, member 2
chr4_-_47916613 0.37 ENST00000381538.3
ENST00000329043.3
NFXL1
nuclear transcription factor, X-box binding-like 1
chr15_+_79165151 0.37 ENST00000331268.5
MORF4L1
mortality factor 4 like 1
chr21_-_38338773 0.37 ENST00000399120.1
ENST00000419461.1
HLCS
holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
chr3_+_160117418 0.37 ENST00000465903.1
ENST00000485645.1
ENST00000360111.2
ENST00000472991.1
ENST00000467468.1
ENST00000469762.1
ENST00000489573.1
ENST00000462787.1
ENST00000490207.1
ENST00000485867.1
SMC4
structural maintenance of chromosomes 4
chr10_-_95462265 0.37 ENST00000536233.1
ENST00000359204.4
ENST00000371430.2
ENST00000394100.2
FRA10AC1
fragile site, folic acid type, rare, fra(10)(q23.3) or fra(10)(q24.2) candidate 1
chr4_-_76439483 0.36 ENST00000380840.2
ENST00000513257.1
ENST00000507014.1
RCHY1
ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
chr6_-_166755995 0.36 ENST00000361731.3
SFT2D1
SFT2 domain containing 1
chr7_+_117824210 0.36 ENST00000422760.1
ENST00000411938.1
NAA38
N(alpha)-acetyltransferase 38, NatC auxiliary subunit
chr19_-_59084647 0.36 ENST00000594234.1
ENST00000596039.1
MZF1
myeloid zinc finger 1
chr20_+_43104541 0.36 ENST00000372906.2
ENST00000456317.1
TTPAL
tocopherol (alpha) transfer protein-like
chr6_+_122931366 0.36 ENST00000368452.2
ENST00000368448.1
ENST00000392490.1
PKIB
protein kinase (cAMP-dependent, catalytic) inhibitor beta
chr7_-_84122033 0.36 ENST00000424555.1
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr19_+_48958766 0.36 ENST00000342291.2
KCNJ14
potassium inwardly-rectifying channel, subfamily J, member 14
chr13_-_22033392 0.36 ENST00000320220.9
ENST00000415724.1
ENST00000422251.1
ENST00000382466.3
ENST00000542645.1
ENST00000400590.3
ZDHHC20
zinc finger, DHHC-type containing 20
chr7_-_77427676 0.35 ENST00000257663.3
TMEM60
transmembrane protein 60
chr18_-_2571210 0.35 ENST00000577166.1
METTL4
methyltransferase like 4
chr6_-_110500826 0.35 ENST00000265601.3
ENST00000447287.1
ENST00000444391.1
WASF1
WAS protein family, member 1
chr4_-_39460496 0.35 ENST00000449470.2
RPL9
ribosomal protein L9
chr2_-_153032484 0.35 ENST00000263904.4
STAM2
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr1_-_26147149 0.35 ENST00000536896.1
AL020996.1
Uncharacterized protein
chr7_+_23636992 0.35 ENST00000307471.3
ENST00000409765.1
CCDC126
coiled-coil domain containing 126
chr13_-_52026730 0.35 ENST00000420668.2
INTS6
integrator complex subunit 6
chr4_+_89300158 0.35 ENST00000502870.1
HERC6
HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
chr1_+_244816237 0.35 ENST00000302550.11
DESI2
desumoylating isopeptidase 2
chr1_-_46642154 0.34 ENST00000540385.1
PIK3R3
phosphoinositide-3-kinase, regulatory subunit 3 (gamma)
chr1_-_91487770 0.34 ENST00000337393.5
ZNF644
zinc finger protein 644
chr15_+_68570062 0.34 ENST00000306917.4
FEM1B
fem-1 homolog b (C. elegans)
chr4_-_157892055 0.34 ENST00000422544.2
PDGFC
platelet derived growth factor C
chr12_+_88429223 0.34 ENST00000356891.3
C12orf29
chromosome 12 open reading frame 29
chr1_+_67390578 0.33 ENST00000371018.3
ENST00000355977.6
ENST00000357692.2
ENST00000401041.1
ENST00000371016.1
ENST00000371014.1
ENST00000371012.2
MIER1
mesoderm induction early response 1, transcriptional regulator
chr8_-_90996459 0.33 ENST00000517337.1
ENST00000409330.1
NBN
nibrin
chr14_-_51027838 0.33 ENST00000555216.1
MAP4K5
mitogen-activated protein kinase kinase kinase kinase 5
chr12_+_64798095 0.33 ENST00000332707.5
XPOT
exportin, tRNA
chr6_-_97345689 0.33 ENST00000316149.7
NDUFAF4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 4
chr2_+_228337079 0.33 ENST00000409315.1
ENST00000373671.3
ENST00000409171.1
AGFG1
ArfGAP with FG repeats 1
chr14_-_39639523 0.33 ENST00000330149.5
ENST00000554018.1
ENST00000347691.5
TRAPPC6B
trafficking protein particle complex 6B
chr1_-_222763101 0.33 ENST00000391883.2
ENST00000366890.1
TAF1A
TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
chr10_-_126480381 0.33 ENST00000368836.2
METTL10
methyltransferase like 10
chr4_-_106394866 0.33 ENST00000502596.1
PPA2
pyrophosphatase (inorganic) 2
chr11_-_61596753 0.33 ENST00000448607.1
ENST00000421879.1
FADS1
fatty acid desaturase 1
chr14_-_36789783 0.33 ENST00000605579.1
ENST00000604336.1
ENST00000359527.7
ENST00000603139.1
ENST00000318473.7
MBIP
MAP3K12 binding inhibitory protein 1
chr3_-_170587974 0.33 ENST00000463836.1
RPL22L1
ribosomal protein L22-like 1
chr9_+_79792269 0.33 ENST00000376634.4
ENST00000376636.3
ENST00000360280.3
VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr2_+_95831529 0.33 ENST00000295210.6
ENST00000453539.2
ZNF2
zinc finger protein 2
chr11_-_2906979 0.32 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C
cyclin-dependent kinase inhibitor 1C (p57, Kip2)
chr19_+_39759154 0.32 ENST00000331982.5
IFNL2
interferon, lambda 2
chr2_-_55277654 0.32 ENST00000337526.6
ENST00000317610.7
ENST00000357732.4
RTN4
reticulon 4
chr12_+_104359576 0.32 ENST00000392872.3
ENST00000436021.2
TDG
thymine-DNA glycosylase
chr10_-_96122682 0.32 ENST00000371361.3
NOC3L
nucleolar complex associated 3 homolog (S. cerevisiae)
chr2_+_204103733 0.32 ENST00000443941.1
CYP20A1
cytochrome P450, family 20, subfamily A, polypeptide 1
chr3_-_101232019 0.32 ENST00000394095.2
ENST00000394091.1
ENST00000394094.2
ENST00000358203.3
ENST00000348610.3
ENST00000314261.7
SENP7
SUMO1/sentrin specific peptidase 7
chr14_+_73563735 0.32 ENST00000532192.1
RBM25
RNA binding motif protein 25
chr11_+_86085778 0.32 ENST00000354755.1
ENST00000278487.3
ENST00000531271.1
ENST00000445632.2
CCDC81
coiled-coil domain containing 81
chr2_-_169769787 0.32 ENST00000451987.1
SPC25
SPC25, NDC80 kinetochore complex component
chr1_-_247094628 0.32 ENST00000366508.1
ENST00000326225.3
ENST00000391829.2
AHCTF1
AT hook containing transcription factor 1
chr1_+_178694362 0.32 ENST00000367634.2
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr1_+_222885884 0.32 ENST00000340934.5
BROX
BRO1 domain and CAAX motif containing
chr14_-_35099377 0.32 ENST00000362031.4
SNX6
sorting nexin 6
chr9_+_88556036 0.31 ENST00000361671.5
ENST00000416045.1
NAA35
N(alpha)-acetyltransferase 35, NatC auxiliary subunit
chr15_+_84841242 0.31 ENST00000558195.1
RP11-182J1.16
ubiquitin-conjugating enzyme E2Q family member 2-like
chr15_-_55489097 0.31 ENST00000260443.4
RSL24D1
ribosomal L24 domain containing 1
chr9_+_86595626 0.31 ENST00000445877.1
ENST00000325875.3
RMI1
RecQ mediated genome instability 1
chr1_+_154301264 0.31 ENST00000341822.2
ATP8B2
ATPase, aminophospholipid transporter, class I, type 8B, member 2
chr3_-_50605150 0.31 ENST00000357203.3
C3orf18
chromosome 3 open reading frame 18
chr13_-_50018140 0.31 ENST00000410043.1
ENST00000347776.5
CAB39L
calcium binding protein 39-like
chr4_-_175205407 0.31 ENST00000393674.2
FBXO8
F-box protein 8
chr6_-_46703430 0.31 ENST00000537365.1
PLA2G7
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr17_-_41465674 0.30 ENST00000592135.1
ENST00000587874.1
ENST00000588654.1
ENST00000592094.1
LINC00910
long intergenic non-protein coding RNA 910
chr8_+_59323823 0.30 ENST00000399598.2
UBXN2B
UBX domain protein 2B
chr6_+_52930237 0.30 ENST00000323557.7
FBXO9
F-box protein 9
chr2_-_224702201 0.30 ENST00000446015.2
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr12_-_31158902 0.30 ENST00000544329.1
ENST00000418254.2
ENST00000222396.5
RP11-551L14.4
RP11-551L14.4
chr11_+_95523823 0.30 ENST00000538658.1
CEP57
centrosomal protein 57kDa
chr8_-_97273807 0.30 ENST00000517720.1
ENST00000287025.3
ENST00000523821.1
MTERFD1
MTERF domain containing 1
chr1_-_173991434 0.30 ENST00000367696.2
RC3H1
ring finger and CCCH-type domains 1
chr10_-_25010795 0.30 ENST00000416305.1
ENST00000376410.2
ARHGAP21
Rho GTPase activating protein 21
chr15_-_66084428 0.30 ENST00000443035.3
ENST00000431932.2
DENND4A
DENN/MADD domain containing 4A
chr4_-_102268484 0.30 ENST00000394853.4
PPP3CA
protein phosphatase 3, catalytic subunit, alpha isozyme
chr5_-_37371163 0.30 ENST00000513532.1
NUP155
nucleoporin 155kDa
chr17_+_55334364 0.30 ENST00000322684.3
ENST00000579590.1
MSI2
musashi RNA-binding protein 2
chr6_+_74405501 0.29 ENST00000437994.2
ENST00000422508.2
CD109
CD109 molecule
chr10_+_94451574 0.29 ENST00000492654.2
HHEX
hematopoietically expressed homeobox
chr13_-_50018241 0.29 ENST00000409308.1
CAB39L
calcium binding protein 39-like
chrX_-_30877837 0.29 ENST00000378930.3
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of CXXC1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.3 1.2 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.3 2.0 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.2 0.7 GO:0030327 prenylated protein catabolic process(GO:0030327) CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.2 1.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.2 0.8 GO:0010430 fatty acid omega-oxidation(GO:0010430)
0.2 0.7 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.2 0.7 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.2 0.7 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244) positive regulation of connective tissue replacement(GO:1905205)
0.2 0.7 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 1.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.2 1.1 GO:0046469 platelet activating factor metabolic process(GO:0046469)
0.2 0.6 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 3.2 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.4 GO:0050720 interleukin-1 beta biosynthetic process(GO:0050720)
0.1 0.8 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.1 0.4 GO:0035508 positive regulation of myosin-light-chain-phosphatase activity(GO:0035508)
0.1 0.4 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.1 0.5 GO:0006850 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.1 0.9 GO:0097068 response to thyroxine(GO:0097068) response to L-phenylalanine derivative(GO:1904386)
0.1 0.2 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.1 0.8 GO:0097501 detoxification of inorganic compound(GO:0061687) stress response to metal ion(GO:0097501)
0.1 3.4 GO:0006999 nuclear pore organization(GO:0006999)
0.1 0.4 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.1 0.8 GO:0051383 kinetochore organization(GO:0051383)
0.1 1.0 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.4 GO:0001188 RNA polymerase I transcriptional preinitiation complex assembly(GO:0001188) RNA polymerase I transcriptional preinitiation complex assembly at the promoter for the nuclear large rRNA transcript(GO:0001189)
0.1 0.4 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.2 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.1 0.3 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.4 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.3 GO:0046041 ITP metabolic process(GO:0046041)
0.1 0.4 GO:1903045 neural crest cell migration involved in sympathetic nervous system development(GO:1903045)
0.1 0.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.3 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.3 GO:0007231 osmosensory signaling pathway(GO:0007231)
0.1 0.3 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.5 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.1 0.2 GO:0035408 histone H3-T6 phosphorylation(GO:0035408)
0.1 0.4 GO:0042701 progesterone secretion(GO:0042701)
0.1 0.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.1 0.3 GO:1904501 glial cell fate determination(GO:0007403) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 0.2 GO:0006433 prolyl-tRNA aminoacylation(GO:0006433)
0.1 0.4 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.2 GO:0071264 regulation of eIF2 alpha phosphorylation by amino acid starvation(GO:0060733) regulation of translational initiation in response to starvation(GO:0071262) positive regulation of translational initiation in response to starvation(GO:0071264)
0.1 0.2 GO:0006679 glucosylceramide biosynthetic process(GO:0006679)
0.1 0.6 GO:0060978 angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.1 0.2 GO:0006579 amino-acid betaine catabolic process(GO:0006579)
0.1 0.3 GO:0019605 butyrate metabolic process(GO:0019605)
0.1 0.3 GO:0071344 diphosphate metabolic process(GO:0071344)
0.1 0.2 GO:0071301 cellular response to vitamin B1(GO:0071301) response to formaldehyde(GO:1904404)
0.1 0.5 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.1 0.2 GO:1903567 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.1 0.3 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 0.2 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085) negative regulation of inward rectifier potassium channel activity(GO:1903609)
0.1 0.2 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.1 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.1 0.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.6 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.1 0.3 GO:0044782 cilium organization(GO:0044782)
0.1 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.1 GO:1904398 positive regulation of neuromuscular junction development(GO:1904398)
0.1 0.7 GO:0060083 smooth muscle contraction involved in micturition(GO:0060083)
0.1 0.3 GO:1902957 negative regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902957)
0.1 0.3 GO:0071934 thiamine transmembrane transport(GO:0071934)
0.1 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.2 GO:0001828 inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.0 0.3 GO:0034670 chemotaxis to arachidonic acid(GO:0034670) response to arachidonic acid(GO:1904550)
0.0 0.4 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0 0.3 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.5 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 1.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.2 GO:0006781 succinyl-CoA pathway(GO:0006781)
0.0 0.5 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.3 GO:0033489 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.2 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0046504 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.3 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.6 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.0 0.5 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.2 GO:0055011 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.0 0.3 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.7 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 1.1 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 1.1 GO:0016254 preassembly of GPI anchor in ER membrane(GO:0016254)
0.0 0.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
0.0 0.2 GO:0016197 endosomal transport(GO:0016197)
0.0 0.3 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.0 0.2 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.0 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.2 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.0 0.4 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.4 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.9 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.6 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:0015817 histidine transport(GO:0015817) L-histidine transmembrane transport(GO:0089709) L-histidine transport(GO:1902024)
0.0 0.1 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.2 GO:0070458 cellular detoxification of nitrogen compound(GO:0070458)
0.0 0.4 GO:0016139 glycoside catabolic process(GO:0016139)
0.0 0.2 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.1 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.7 GO:0007379 segment specification(GO:0007379)
0.0 0.2 GO:0070901 mitochondrial tRNA methylation(GO:0070901)
0.0 0.1 GO:0070895 transposon integration(GO:0070893) regulation of transposon integration(GO:0070894) negative regulation of transposon integration(GO:0070895)
0.0 0.2 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.2 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.6 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.0 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.3 GO:2001300 lipoxin metabolic process(GO:2001300)
0.0 0.3 GO:0051583 dopamine uptake involved in synaptic transmission(GO:0051583) catecholamine uptake involved in synaptic transmission(GO:0051934) catecholamine uptake(GO:0090493) dopamine uptake(GO:0090494)
0.0 0.0 GO:0070734 histone H3-K27 methylation(GO:0070734)
0.0 0.1 GO:0002728 negative regulation of natural killer cell cytokine production(GO:0002728)
0.0 0.2 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.2 GO:0003383 apical constriction(GO:0003383)
0.0 0.2 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.3 GO:0003413 chondrocyte differentiation involved in endochondral bone morphogenesis(GO:0003413)
0.0 0.1 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.0 0.1 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.0 0.1 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.2 GO:0021699 cerebellum maturation(GO:0021590) cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0000012 single strand break repair(GO:0000012)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.3 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.2 GO:0061458 reproductive system development(GO:0061458)
0.0 0.1 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.0 0.3 GO:0051608 histamine transport(GO:0051608)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.2 GO:1902612 regulation of anti-Mullerian hormone signaling pathway(GO:1902612) negative regulation of anti-Mullerian hormone signaling pathway(GO:1902613) anti-Mullerian hormone signaling pathway(GO:1990262)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.6 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.2 GO:1903333 negative regulation of protein folding(GO:1903333)
0.0 0.4 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.5 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0097359 UDP-glucosylation(GO:0097359)
0.0 0.1 GO:2000691 regulation of cardiac muscle cell myoblast differentiation(GO:2000690) negative regulation of cardiac muscle cell myoblast differentiation(GO:2000691)
0.0 0.5 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.1 GO:0035441 cell migration involved in vasculogenesis(GO:0035441) histone H3-K36 trimethylation(GO:0097198)
0.0 0.1 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258)
0.0 0.2 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0038178 complement component C5a signaling pathway(GO:0038178)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.0 0.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.6 GO:0032012 regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.4 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.8 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.1 GO:0038193 thromboxane A2 signaling pathway(GO:0038193)
0.0 0.2 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.0 0.1 GO:0042938 positive regulation of cellular pH reduction(GO:0032849) dipeptide transport(GO:0042938)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.5 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.5 GO:0048490 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.9 GO:0060765 regulation of androgen receptor signaling pathway(GO:0060765)
0.0 0.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.3 GO:0002934 desmosome organization(GO:0002934)
0.0 0.0 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.1 GO:0043606 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 1.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.1 GO:0048864 stem cell development(GO:0048864)
0.0 0.2 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.6 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:1990592 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.6 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0030573 bile acid catabolic process(GO:0030573)
0.0 0.2 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.8 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.1 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.2 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.1 GO:0071279 cellular response to cobalt ion(GO:0071279)
0.0 0.5 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0009822 alkaloid catabolic process(GO:0009822)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.1 GO:0043335 protein unfolding(GO:0043335)
0.0 0.1 GO:0021779 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.0 0.1 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.0 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.1 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.3 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.0 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.0 0.3 GO:0002385 mucosal immune response(GO:0002385)
0.0 0.1 GO:0019060 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.0 0.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.2 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 0.0 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.5 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.0 0.1 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.2 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.4 GO:0016180 snRNA processing(GO:0016180)
0.0 0.2 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.2 GO:0098887 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887)
0.0 0.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.0 0.2 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.3 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.3 GO:0015838 amino-acid betaine transport(GO:0015838)
0.0 0.2 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.1 GO:0021830 interneuron migration from the subpallium to the cortex(GO:0021830)
0.0 0.0 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.0 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0046984 regulation of translational initiation by iron(GO:0006447) regulation of hemoglobin biosynthetic process(GO:0046984)
0.0 0.1 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.2 GO:0048714 positive regulation of oligodendrocyte differentiation(GO:0048714)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.1 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.3 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.5 GO:0034314 Arp2/3 complex-mediated actin nucleation(GO:0034314)
0.0 0.3 GO:0036109 alpha-linolenic acid metabolic process(GO:0036109)
0.0 0.1 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.0 GO:0035350 FAD transport(GO:0015883) FAD transmembrane transport(GO:0035350)
0.0 0.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.1 GO:0019346 homoserine metabolic process(GO:0009092) 10-formyltetrahydrofolate biosynthetic process(GO:0009257) transsulfuration(GO:0019346)
0.0 0.3 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.1 GO:1903051 negative regulation of proteolysis involved in cellular protein catabolic process(GO:1903051) negative regulation of cellular protein catabolic process(GO:1903363)
0.0 0.0 GO:0043006 activation of phospholipase A2 activity by calcium-mediated signaling(GO:0043006)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.2 0.7 GO:0044611 nuclear pore inner ring(GO:0044611)
0.2 0.5 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.1 0.9 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.1 0.7 GO:0031417 NatC complex(GO:0031417)
0.1 2.5 GO:0005652 nuclear lamina(GO:0005652)
0.1 1.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.6 GO:0097422 tubular endosome(GO:0097422)
0.1 1.0 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.2 GO:0034455 t-UTP complex(GO:0034455)
0.1 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.7 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.3 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 0.4 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.1 0.8 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.2 GO:0098843 postsynaptic endocytic zone(GO:0098843) postsynaptic endocytic zone membrane(GO:0098844)
0.1 0.7 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.2 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.1 1.0 GO:0071439 clathrin complex(GO:0071439)
0.1 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.4 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.1 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.3 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.3 GO:0097443 sorting endosome(GO:0097443)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0017102 methionyl glutamyl tRNA synthetase complex(GO:0017102)
0.0 0.3 GO:1990589 ATF4-CREB1 transcription factor complex(GO:1990589)
0.0 0.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 1.0 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.6 GO:0032039 integrator complex(GO:0032039)
0.0 0.9 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 1.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0031592 centrosomal corona(GO:0031592)
0.0 0.6 GO:0044754 autolysosome(GO:0044754)
0.0 1.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 1.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0000502 proteasome complex(GO:0000502)
0.0 0.2 GO:0030678 mitochondrial ribonuclease P complex(GO:0030678)
0.0 0.4 GO:0000796 condensin complex(GO:0000796)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0075341 host cell PML body(GO:0075341)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0098845 postsynaptic endosome(GO:0098845)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.3 GO:0072588 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.6 GO:0031045 dense core granule(GO:0031045)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.6 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.5 GO:0005858 axonemal dynein complex(GO:0005858)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.4 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.6 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.1 GO:0034753 nuclear aryl hydrocarbon receptor complex(GO:0034753)
0.0 0.3 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.1 GO:0097224 sperm connecting piece(GO:0097224)
0.0 0.2 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.5 GO:0031332 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 1.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.2 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0005694 chromosome(GO:0005694)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0097362 MCM8-MCM9 complex(GO:0097362)
0.0 0.2 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.1 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0000145 exocyst(GO:0000145)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0043541 UDP-N-acetylglucosamine transferase complex(GO:0043541)
0.0 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 0.7 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.2 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0032797 SMN complex(GO:0032797)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.0 0.1 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.3 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.0 GO:0097489 multivesicular body, internal vesicle lumen(GO:0097489)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0016992 lipoate synthase activity(GO:0016992) radical SAM enzyme activity(GO:0070283)
0.3 0.9 GO:0008808 cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) CDP-diacylglycerol-phosphatidylglycerol phosphatidyltransferase activity(GO:0043337)
0.2 0.7 GO:0019781 NEDD8 activating enzyme activity(GO:0019781)
0.2 0.6 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.2 0.6 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.2 0.5 GO:0008969 phosphohistidine phosphatase activity(GO:0008969)
0.2 1.2 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
0.2 0.5 GO:0030366 molybdopterin synthase activity(GO:0030366)
0.2 1.6 GO:0043515 kinetochore binding(GO:0043515)
0.1 0.1 GO:0009055 electron carrier activity(GO:0009055)
0.1 0.6 GO:0000248 C-5 sterol desaturase activity(GO:0000248) sterol desaturase activity(GO:0070704)
0.1 0.5 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 0.8 GO:0035252 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.4 GO:0004583 dolichyl-phosphate-glucose-glycolipid alpha-glucosyltransferase activity(GO:0004583)
0.1 0.4 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.9 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 0.3 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.1 0.2 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.1 0.2 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 0.6 GO:0034046 poly(G) binding(GO:0034046)
0.1 0.2 GO:0004827 proline-tRNA ligase activity(GO:0004827)
0.1 0.7 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.2 GO:0047322 [hydroxymethylglutaryl-CoA reductase (NADPH)] kinase activity(GO:0047322) [acetyl-CoA carboxylase] kinase activity(GO:0050405)
0.1 0.3 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.4 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.7 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.1 0.5 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.2 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.1 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.2 GO:0061663 NEDD8 ligase activity(GO:0061663)
0.1 0.2 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.3 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.1 0.2 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.2 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.1 0.3 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.9 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 2.1 GO:0008409 5'-3' exonuclease activity(GO:0008409)
0.1 0.2 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.5 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.2 GO:1901474 azole transmembrane transporter activity(GO:1901474)
0.1 0.2 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.1 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.6 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.0 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 2.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.2 GO:0005334 norepinephrine:sodium symporter activity(GO:0005334)
0.0 0.3 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:0047708 biotinidase activity(GO:0047708)
0.0 0.9 GO:0019841 retinol binding(GO:0019841)
0.0 0.5 GO:0009374 biotin binding(GO:0009374)
0.0 0.1 GO:0004772 sterol O-acyltransferase activity(GO:0004772) cholesterol O-acyltransferase activity(GO:0034736)
0.0 0.1 GO:0051500 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.0 0.2 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.1 GO:0030272 5-formyltetrahydrofolate cyclo-ligase activity(GO:0030272)
0.0 0.4 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0071566 UFM1 activating enzyme activity(GO:0071566)
0.0 0.1 GO:0000035 acyl binding(GO:0000035) phosphopantetheine binding(GO:0031177)
0.0 0.3 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.2 GO:0016429 tRNA (adenine) methyltransferase activity(GO:0016426) tRNA (adenine-N1-)-methyltransferase activity(GO:0016429)
0.0 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0047631 ADP-ribose diphosphatase activity(GO:0047631)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.6 GO:0034452 dynactin binding(GO:0034452)
0.0 0.4 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.3 GO:1990763 arrestin family protein binding(GO:1990763)
0.0 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.2 GO:0004775 succinate-CoA ligase (ADP-forming) activity(GO:0004775)
0.0 0.2 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0016298 lipase activity(GO:0016298)
0.0 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.4 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0016768 spermine synthase activity(GO:0016768)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.2 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.1 GO:0004397 histidine ammonia-lyase activity(GO:0004397)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.1 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.1 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.5 GO:0008199 ferric iron binding(GO:0008199)
0.0 1.1 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.1 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.0 0.1 GO:0004530 deoxyribonuclease I activity(GO:0004530)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.3 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.1 GO:0047225 acetylgalactosaminyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0047225)
0.0 0.1 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.3 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.4 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0003980 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.1 GO:0005055 laminin receptor activity(GO:0005055)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0005114 transforming growth factor beta receptor activity, type I(GO:0005025) type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.1 GO:0004878 complement component C5a receptor activity(GO:0004878)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0090556 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0004960 thromboxane receptor activity(GO:0004960) thromboxane A2 receptor activity(GO:0004961)
0.0 0.1 GO:0047150 betaine-homocysteine S-methyltransferase activity(GO:0047150)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0004365 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893) V2 vasopressin receptor binding(GO:0031896)
0.0 1.0 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 1.4 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.5 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.9 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.4 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.4 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.2 GO:0008201 heparin binding(GO:0008201)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.3 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.7 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.1 GO:0032810 sterol response element binding(GO:0032810)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0043022 ribosome binding(GO:0043022)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0043813 phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.2 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.1 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.0 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.0 GO:0035248 alpha-1,4-N-acetylgalactosaminyltransferase activity(GO:0035248)
0.0 0.9 GO:0008235 metalloexopeptidase activity(GO:0008235)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.2 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0038025 reelin receptor activity(GO:0038025)
0.0 0.5 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.0 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.5 PID BARD1 PATHWAY BARD1 signaling events
0.0 2.5 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.1 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 0.9 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.3 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.3 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.8 PID AURORA B PATHWAY Aurora B signaling
0.0 0.5 PID FANCONI PATHWAY Fanconi anemia pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.1 4.1 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0 1.7 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.7 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.3 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 5.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.1 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.7 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.1 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 1.3 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 1.0 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.6 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.2 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.5 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.7 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.5 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade