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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CREB5_CREM_JUNB

Z-value: 0.66

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Transcription factors associated with CREB5_CREM_JUNB

Gene Symbol Gene ID Gene Info
CREB5
ENSG00000146592.12 CREB5
CREM
ENSG00000095794.15 CREM
JUNB
ENSG00000171223.4 JUNB

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CREMhg19_v2_chr10_+_35415851_354159410.862.7e-02Click!
CREB5hg19_v2_chr7_+_28448995_284490110.621.9e-01Click!
JUNBhg19_v2_chr19_+_12902289_12902310-0.602.1e-01Click!

Activity profile of CREB5_CREM_JUNB motif

Sorted Z-values of CREB5_CREM_JUNB motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CREB5_CREM_JUNB

PNG image of the network

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Top targets:

Promoter Score Transcript Gene Gene Info
chr6_+_26204825 0.54 ENST00000360441.4
 HIST1H4E
 histone cluster 1, H4e
chr9_-_99381660 0.49 ENST00000375240.3
ENST00000463569.1
 CDC14B
 cell division cycle 14B
chr7_+_30174668 0.47 ENST00000415604.1
 C7orf41
 maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr15_+_75287861 0.40 ENST00000425597.3
ENST00000562327.1
ENST00000568018.1
ENST00000562212.1
ENST00000567920.1
ENST00000566872.1
ENST00000361900.6
ENST00000545456.1
 SCAMP5
 secretory carrier membrane protein 5
chr2_+_220408724 0.33 ENST00000421791.1
ENST00000373883.3
ENST00000451952.1
 TMEM198
 transmembrane protein 198
chr20_+_55099542 0.32 ENST00000371328.3
 FAM209A
 family with sequence similarity 209, member A
chr14_+_68086515 0.31 ENST00000261783.3
 ARG2
 arginase 2
chr1_-_203274387 0.31 ENST00000432511.1
 RP11-134P9.1
 long intergenic non-protein coding RNA 1136
chr11_+_64004888 0.30 ENST00000541681.1
 VEGFB
 vascular endothelial growth factor B
chr19_+_1954632 0.30 ENST00000589350.1
 CSNK1G2
 casein kinase 1, gamma 2
chr7_+_30174426 0.29 ENST00000324453.8
 C7orf41
 maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr7_+_30174574 0.29 ENST00000409688.1
 C7orf41
 maturin, neural progenitor differentiation regulator homolog (Xenopus)
chr3_-_101395936 0.28 ENST00000461821.1
 ZBTB11
 zinc finger and BTB domain containing 11
chr17_-_43210580 0.28 ENST00000538093.1
ENST00000590644.1
 PLCD3
 phospholipase C, delta 3
chr9_-_99382065 0.27 ENST00000265659.2
ENST00000375241.1
ENST00000375236.1
 CDC14B
 cell division cycle 14B
chr22_+_31518938 0.26 ENST00000412985.1
ENST00000331075.5
ENST00000412277.2
ENST00000420017.1
ENST00000400294.2
ENST00000405300.1
ENST00000404390.3
 INPP5J
 inositol polyphosphate-5-phosphatase J
chr3_+_159570722 0.25 ENST00000482804.1
 SCHIP1
 schwannomin interacting protein 1
chr12_-_4754356 0.25 ENST00000540967.1
 AKAP3
 A kinase (PRKA) anchor protein 3
chr10_-_14920599 0.25 ENST00000609399.1
 RP11-398C13.6
 RP11-398C13.6
chr5_-_99870890 0.23 ENST00000499025.1
 CTD-2001C12.1
 CTD-2001C12.1
chr6_-_31774714 0.22 ENST00000375661.5
 LSM2
 LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr7_-_6388389 0.22 ENST00000578372.1
 FAM220A
 family with sequence similarity 220, member A
chr5_+_133707252 0.22 ENST00000506787.1
ENST00000507277.1
 UBE2B
 ubiquitin-conjugating enzyme E2B
chr12_+_124997766 0.21 ENST00000543970.1
 RP11-83B20.1
 RP11-83B20.1
chr16_+_29911864 0.21 ENST00000308748.5
 ASPHD1
 aspartate beta-hydroxylase domain containing 1
chr1_+_70820451 0.21 ENST00000361764.4
ENST00000359875.5
ENST00000370940.5
ENST00000531950.1
ENST00000432224.1
 HHLA3
 HERV-H LTR-associating 3
chr17_-_7155775 0.20 ENST00000571409.1
 CTDNEP1
 CTD nuclear envelope phosphatase 1
chr20_+_5892147 0.20 ENST00000455042.1
 CHGB
 chromogranin B (secretogranin 1)
chr6_+_28048753 0.20 ENST00000377325.1
 ZNF165
 zinc finger protein 165
chr7_+_28448995 0.19 ENST00000424599.1
 CREB5
 cAMP responsive element binding protein 5
chr20_+_33146510 0.19 ENST00000397709.1
 MAP1LC3A
 microtubule-associated protein 1 light chain 3 alpha
chr15_-_66790146 0.19 ENST00000316634.5
 SNAPC5
 small nuclear RNA activating complex, polypeptide 5, 19kDa
chr15_+_34394257 0.18 ENST00000397766.2
 PGBD4
 piggyBac transposable element derived 4
chr2_-_202645612 0.18 ENST00000409632.2
ENST00000410052.1
ENST00000467448.1
 ALS2
 amyotrophic lateral sclerosis 2 (juvenile)
chr4_-_156297919 0.18 ENST00000450097.1
 MAP9
 microtubule-associated protein 9
chr3_+_38206975 0.18 ENST00000446845.1
ENST00000311806.3
 OXSR1
 oxidative stress responsive 1
chr12_-_123380610 0.18 ENST00000535765.1
 VPS37B
 vacuolar protein sorting 37 homolog B (S. cerevisiae)
chr22_+_38597889 0.17 ENST00000338483.2
ENST00000538320.1
ENST00000538999.1
ENST00000441709.1
 MAFF
 v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
chr14_+_38065052 0.17 ENST00000556845.1
 TTC6
 tetratricopeptide repeat domain 6
chr1_+_27719148 0.16 ENST00000374024.3
 GPR3
 G protein-coupled receptor 3
chr2_-_224467002 0.16 ENST00000421386.1
ENST00000433889.1
 SCG2
 secretogranin II
chr3_+_63898275 0.16 ENST00000538065.1
 ATXN7
 ataxin 7
chr2_-_25194476 0.16 ENST00000534855.1
 DNAJC27
 DnaJ (Hsp40) homolog, subfamily C, member 27
chr18_+_76829258 0.15 ENST00000588600.1
 ATP9B
 ATPase, class II, type 9B
chr7_+_102292796 0.15 ENST00000436228.2
 SPDYE2B
 speedy/RINGO cell cycle regulator family member E2B
chr8_+_26240666 0.15 ENST00000523949.1
 BNIP3L
 BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr12_-_4754339 0.15 ENST00000228850.1
 AKAP3
 A kinase (PRKA) anchor protein 3
chr5_+_32174483 0.15 ENST00000606994.1
 CTD-2186M15.3
 CTD-2186M15.3
chr6_-_37225391 0.14 ENST00000356757.2
 TMEM217
 transmembrane protein 217
chr21_+_39628780 0.14 ENST00000417042.1
 KCNJ15
 potassium inwardly-rectifying channel, subfamily J, member 15
chr7_+_120590803 0.14 ENST00000315870.5
ENST00000339121.5
ENST00000445699.1
 ING3
 inhibitor of growth family, member 3
chr3_-_130745403 0.14 ENST00000504725.1
ENST00000509060.1
 ASTE1
 asteroid homolog 1 (Drosophila)
chr12_-_112856623 0.13 ENST00000551291.2
 RPL6
 ribosomal protein L6
chr22_+_32340481 0.13 ENST00000397492.1
 YWHAH
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr3_-_9811674 0.13 ENST00000411972.1
 CAMK1
 calcium/calmodulin-dependent protein kinase I
chr7_-_37956409 0.13 ENST00000436072.2
 SFRP4
 secreted frizzled-related protein 4
chr5_-_130868688 0.13 ENST00000504575.1
ENST00000513227.1
 RAPGEF6
 Rap guanine nucleotide exchange factor (GEF) 6
chr12_-_100660833 0.13 ENST00000551642.1
ENST00000416321.1
ENST00000550587.1
ENST00000549249.1
 DEPDC4
 DEP domain containing 4
chr19_+_10527449 0.13 ENST00000592685.1
ENST00000380702.2
 PDE4A
 phosphodiesterase 4A, cAMP-specific
chr1_-_205391178 0.13 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
 LEMD1
 LEM domain containing 1
chr16_-_11367452 0.13 ENST00000327157.2
 PRM3
 protamine 3
chr11_+_66059339 0.12 ENST00000327259.4
 TMEM151A
 transmembrane protein 151A
chr3_+_170075436 0.12 ENST00000476188.1
ENST00000259119.4
ENST00000426052.2
 SKIL
 SKI-like oncogene
chr8_-_116681686 0.12 ENST00000519815.1
 TRPS1
 trichorhinophalangeal syndrome I
chr11_+_18720316 0.12 ENST00000280734.2
 TMEM86A
 transmembrane protein 86A
chr17_+_33914460 0.12 ENST00000537622.2
 AP2B1
 adaptor-related protein complex 2, beta 1 subunit
chr22_+_32340447 0.12 ENST00000248975.5
 YWHAH
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr1_+_85527987 0.12 ENST00000326813.8
ENST00000294664.6
ENST00000528899.1
 WDR63
 WD repeat domain 63
chrX_+_152224766 0.12 ENST00000370265.4
ENST00000447306.1
 PNMA3
 paraneoplastic Ma antigen 3
chr6_-_121655850 0.12 ENST00000422369.1
 TBC1D32
 TBC1 domain family, member 32
chr9_+_70856899 0.12 ENST00000377342.5
ENST00000478048.1
 CBWD3
 COBW domain containing 3
chr4_+_1873100 0.11 ENST00000508803.1
 WHSC1
 Wolf-Hirschhorn syndrome candidate 1
chr20_+_44420570 0.11 ENST00000372622.3
 DNTTIP1
 deoxynucleotidyltransferase, terminal, interacting protein 1
chr5_-_78809950 0.11 ENST00000334082.6
 HOMER1
 homer homolog 1 (Drosophila)
chrX_+_102024075 0.11 ENST00000431616.1
ENST00000440496.1
ENST00000420471.1
ENST00000435966.1
 LINC00630
 long intergenic non-protein coding RNA 630
chr8_-_18711866 0.11 ENST00000519851.1
 PSD3
 pleckstrin and Sec7 domain containing 3
chr17_-_7835228 0.11 ENST00000303731.4
ENST00000571947.1
ENST00000540486.1
ENST00000572656.1
 TRAPPC1
 trafficking protein particle complex 1
chr17_-_76899275 0.11 ENST00000322630.2
ENST00000586713.1
 DDC8
 Protein DDC8 homolog
chr11_-_62457371 0.11 ENST00000317449.4
 LRRN4CL
 LRRN4 C-terminal like
chr3_-_156877997 0.11 ENST00000295926.3
 CCNL1
 cyclin L1
chr17_+_29421900 0.11 ENST00000358273.4
ENST00000356175.3
 NF1
 neurofibromin 1
chr14_-_93651186 0.10 ENST00000556883.1
ENST00000298894.4
 MOAP1
 modulator of apoptosis 1
chr1_+_39456895 0.10 ENST00000432648.3
ENST00000446189.2
ENST00000372984.4
 AKIRIN1
 akirin 1
chr5_-_141703713 0.10 ENST00000511815.1
 SPRY4
 sprouty homolog 4 (Drosophila)
chr1_+_22379179 0.10 ENST00000315554.8
ENST00000421089.2
 CDC42
 cell division cycle 42
chr2_-_224467093 0.10 ENST00000305409.2
 SCG2
 secretogranin II
chr20_-_44420507 0.10 ENST00000243938.4
 WFDC3
 WAP four-disulfide core domain 3
chr2_+_11864458 0.10 ENST00000396098.1
ENST00000396099.1
ENST00000425416.2
 LPIN1
 lipin 1
chr12_+_100660909 0.10 ENST00000549687.1
 SCYL2
 SCY1-like 2 (S. cerevisiae)
chr9_-_111696224 0.10 ENST00000537196.1
 IKBKAP
 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr17_+_33914276 0.10 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
 AP2B1
 adaptor-related protein complex 2, beta 1 subunit
chr7_-_140624499 0.10 ENST00000288602.6
 BRAF
 v-raf murine sarcoma viral oncogene homolog B
chr17_-_40540377 0.10 ENST00000404395.3
ENST00000389272.3
ENST00000585517.1
ENST00000588065.1
 STAT3
 signal transducer and activator of transcription 3 (acute-phase response factor)
chr4_+_75311019 0.10 ENST00000502307.1
 AREG
 amphiregulin
chr20_+_33292507 0.10 ENST00000414082.1
 TP53INP2
 tumor protein p53 inducible nuclear protein 2
chr1_+_166808692 0.10 ENST00000367876.4
 POGK
 pogo transposable element with KRAB domain
chr1_-_245026388 0.09 ENST00000440865.1
 HNRNPU
 heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr8_+_38243967 0.09 ENST00000524874.1
ENST00000379957.4
ENST00000523983.2
 LETM2
 leucine zipper-EF-hand containing transmembrane protein 2
chr1_+_17531614 0.09 ENST00000375471.4
 PADI1
 peptidyl arginine deiminase, type I
chr7_+_120591170 0.09 ENST00000431467.1
 ING3
 inhibitor of growth family, member 3
chr20_+_44420617 0.09 ENST00000449078.1
ENST00000456939.1
 DNTTIP1
 deoxynucleotidyltransferase, terminal, interacting protein 1
chrX_-_152245978 0.09 ENST00000538162.2
 PNMA6D
 paraneoplastic Ma antigen family member 6D (pseudogene)
chr19_-_50528584 0.09 ENST00000594092.1
ENST00000443401.2
ENST00000594948.1
ENST00000377011.2
ENST00000593919.1
ENST00000601324.1
ENST00000316763.3
ENST00000601341.1
ENST00000600259.1
 VRK3
 vaccinia related kinase 3
chr4_+_668348 0.09 ENST00000511290.1
 MYL5
 myosin, light chain 5, regulatory
chr19_-_52227221 0.09 ENST00000222115.1
ENST00000540069.2
 HAS1
 hyaluronan synthase 1
chr9_-_179018 0.09 ENST00000431099.2
ENST00000382447.4
ENST00000382389.1
ENST00000377447.3
ENST00000314367.10
ENST00000356521.4
ENST00000382393.1
ENST00000377400.4
 CBWD1
 COBW domain containing 1
chr22_-_39096925 0.09 ENST00000456626.1
ENST00000412832.1
 JOSD1
 Josephin domain containing 1
chr11_+_3819049 0.09 ENST00000396986.2
ENST00000300730.6
ENST00000532535.1
ENST00000396993.4
ENST00000396991.2
ENST00000532523.1
ENST00000459679.1
ENST00000464261.1
ENST00000464906.2
ENST00000464441.1
 PGAP2
 post-GPI attachment to proteins 2
chr5_-_39462390 0.09 ENST00000511792.1
 DAB2
 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
chr7_-_25164969 0.09 ENST00000305786.2
 CYCS
 cytochrome c, somatic
chrX_-_135056106 0.09 ENST00000433339.2
 MMGT1
 membrane magnesium transporter 1
chr16_+_22825475 0.09 ENST00000261374.3
 HS3ST2
 heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr19_-_50528392 0.09 ENST00000600137.1
ENST00000597215.1
 VRK3
 vaccinia related kinase 3
chr19_+_16187085 0.09 ENST00000300933.4
 TPM4
 tropomyosin 4
chr1_+_1115056 0.09 ENST00000379288.3
 TTLL10
 tubulin tyrosine ligase-like family, member 10
chr11_-_72496976 0.09 ENST00000539138.1
ENST00000542989.1
 STARD10
 StAR-related lipid transfer (START) domain containing 10
chr3_+_3168692 0.09 ENST00000402675.1
ENST00000413000.1
 TRNT1
 tRNA nucleotidyl transferase, CCA-adding, 1
chr8_+_42128861 0.09 ENST00000518983.1
 IKBKB
 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
chr16_+_19079215 0.09 ENST00000544894.2
ENST00000561858.1
 COQ7
 coenzyme Q7 homolog, ubiquinone (yeast)
chr7_+_116660246 0.09 ENST00000434836.1
ENST00000393443.1
ENST00000465133.1
ENST00000477742.1
ENST00000393447.4
ENST00000393444.3
 ST7
 suppression of tumorigenicity 7
chr17_-_7165662 0.09 ENST00000571881.2
ENST00000360325.7
 CLDN7
 claudin 7
chr1_-_209975494 0.09 ENST00000456314.1
 IRF6
 interferon regulatory factor 6
chr7_-_25164868 0.09 ENST00000409409.1
ENST00000409764.1
ENST00000413447.1
 CYCS
 cytochrome c, somatic
chr11_+_18343800 0.09 ENST00000453096.2
 GTF2H1
 general transcription factor IIH, polypeptide 1, 62kDa
chr2_-_202645835 0.09 ENST00000264276.6
 ALS2
 amyotrophic lateral sclerosis 2 (juvenile)
chr1_-_151254362 0.09 ENST00000447795.2
 RP11-126K1.2
 Uncharacterized protein
chr22_-_36357671 0.09 ENST00000408983.2
 RBFOX2
 RNA binding protein, fox-1 homolog (C. elegans) 2
chr6_+_126661253 0.08 ENST00000368326.1
ENST00000368325.1
ENST00000368328.4
 CENPW
 centromere protein W
chr1_-_154164534 0.08 ENST00000271850.7
ENST00000368530.2
 TPM3
 tropomyosin 3
chrX_+_152240819 0.08 ENST00000421798.3
ENST00000535416.1
 PNMA6C
PNMA6A
 paraneoplastic Ma antigen family member 6C
paraneoplastic Ma antigen family member 6A
chr22_-_39096981 0.08 ENST00000427389.1
 JOSD1
 Josephin domain containing 1
chr3_-_130745571 0.08 ENST00000514044.1
ENST00000264992.3
 ASTE1
 asteroid homolog 1 (Drosophila)
chr1_+_168148169 0.08 ENST00000367833.2
 TIPRL
 TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
chr17_-_7155274 0.08 ENST00000318988.6
ENST00000575783.1
ENST00000573600.1
 CTDNEP1
 CTD nuclear envelope phosphatase 1
chr14_-_23446900 0.08 ENST00000556731.1
 AJUBA
 ajuba LIM protein
chr11_-_18343725 0.08 ENST00000531848.1
 HPS5
 Hermansky-Pudlak syndrome 5
chr14_+_104095514 0.08 ENST00000348520.6
ENST00000380038.3
ENST00000389744.4
ENST00000557575.1
ENST00000553286.1
ENST00000347839.6
ENST00000555836.1
ENST00000334553.6
ENST00000246489.7
ENST00000557450.1
ENST00000452929.2
ENST00000554280.1
ENST00000445352.4
 KLC1
 kinesin light chain 1
chr11_-_8680383 0.08 ENST00000299550.6
 TRIM66
 tripartite motif containing 66
chr1_-_204165610 0.08 ENST00000367194.4
 KISS1
 KiSS-1 metastasis-suppressor
chr6_-_53213780 0.08 ENST00000304434.6
ENST00000370918.4
 ELOVL5
 ELOVL fatty acid elongase 5
chr5_+_139055021 0.08 ENST00000502716.1
ENST00000503511.1
 CXXC5
 CXXC finger protein 5
chr4_-_113558014 0.08 ENST00000503172.1
ENST00000505019.1
ENST00000309071.5
 C4orf21
 chromosome 4 open reading frame 21
chrX_-_152343394 0.08 ENST00000370261.1
 PNMA6B
 paraneoplastic Ma antigen family member 6B (pseudogene)
chr12_+_112856690 0.08 ENST00000392597.1
ENST00000351677.2
 PTPN11
 protein tyrosine phosphatase, non-receptor type 11
chr17_-_40540484 0.08 ENST00000588969.1
 STAT3
 signal transducer and activator of transcription 3 (acute-phase response factor)
chr18_-_5540471 0.08 ENST00000581833.1
ENST00000544123.1
ENST00000342933.3
ENST00000400111.3
ENST00000585142.1
 EPB41L3
 erythrocyte membrane protein band 4.1-like 3
chr6_-_53213587 0.08 ENST00000542638.1
ENST00000370913.5
ENST00000541407.1
 ELOVL5
 ELOVL fatty acid elongase 5
chr15_+_89905705 0.08 ENST00000560008.1
ENST00000561327.1
 LINC00925
 long intergenic non-protein coding RNA 925
chr2_+_70142232 0.08 ENST00000540449.1
 MXD1
 MAX dimerization protein 1
chr9_-_127533582 0.08 ENST00000416460.2
 NR6A1
 nuclear receptor subfamily 6, group A, member 1
chr9_-_111696340 0.08 ENST00000374647.5
 IKBKAP
 inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
chr11_-_3818688 0.08 ENST00000355260.3
ENST00000397004.4
ENST00000397007.4
ENST00000532475.1
 NUP98
 nucleoporin 98kDa
chr1_+_22379120 0.08 ENST00000400259.1
ENST00000344548.3
 CDC42
 cell division cycle 42
chr1_+_28099700 0.08 ENST00000440806.2
 STX12
 syntaxin 12
chr6_-_10694766 0.08 ENST00000460742.2
ENST00000259983.3
ENST00000379586.1
 C6orf52
 chromosome 6 open reading frame 52
chr7_-_124569864 0.08 ENST00000609702.1
 POT1
 protection of telomeres 1
chr1_+_25071848 0.08 ENST00000374379.4
 CLIC4
 chloride intracellular channel 4
chr5_+_138210919 0.08 ENST00000522013.1
ENST00000520260.1
ENST00000523298.1
ENST00000520865.1
ENST00000519634.1
ENST00000517533.1
ENST00000523685.1
ENST00000519768.1
ENST00000517656.1
ENST00000521683.1
ENST00000521640.1
ENST00000519116.1
 CTNNA1
 catenin (cadherin-associated protein), alpha 1, 102kDa
chr17_+_74536164 0.08 ENST00000586148.1
 PRCD
 progressive rod-cone degeneration
chr8_+_38243951 0.08 ENST00000297720.5
 LETM2
 leucine zipper-EF-hand containing transmembrane protein 2
chr5_+_172332220 0.08 ENST00000518247.1
ENST00000326654.2
 ERGIC1
 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr2_-_151395525 0.08 ENST00000439275.1
 RND3
 Rho family GTPase 3
chr5_+_159343688 0.08 ENST00000306675.3
 ADRA1B
 adrenoceptor alpha 1B
chr19_+_2841433 0.07 ENST00000334241.4
ENST00000585966.1
ENST00000591539.1
 ZNF555
 zinc finger protein 555
chrX_+_12993202 0.07 ENST00000451311.2
ENST00000380636.1
 TMSB4X
 thymosin beta 4, X-linked
chr8_-_133772870 0.07 ENST00000522334.1
ENST00000519016.1
 TMEM71
 transmembrane protein 71
chr17_+_4643300 0.07 ENST00000433935.1
 ZMYND15
 zinc finger, MYND-type containing 15
chr14_+_32030582 0.07 ENST00000550649.1
ENST00000281081.7
 NUBPL
 nucleotide binding protein-like
chrX_+_12993336 0.07 ENST00000380635.1
 TMSB4X
 thymosin beta 4, X-linked
chr17_-_58603482 0.07 ENST00000585368.1
 APPBP2
 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr15_+_42841008 0.07 ENST00000260372.3
ENST00000568876.1
ENST00000568846.2
ENST00000562398.1
 HAUS2
 HAUS augmin-like complex, subunit 2
chr2_-_198175495 0.07 ENST00000409153.1
ENST00000409919.1
ENST00000539527.1
 ANKRD44
 ankyrin repeat domain 44
chr3_+_185080908 0.07 ENST00000265026.3
 MAP3K13
 mitogen-activated protein kinase kinase kinase 13
chr2_+_152214098 0.07 ENST00000243347.3
 TNFAIP6
 tumor necrosis factor, alpha-induced protein 6
chr5_-_172198190 0.07 ENST00000239223.3
 DUSP1
 dual specificity phosphatase 1
chr14_+_35515582 0.07 ENST00000382406.3
 FAM177A1
 family with sequence similarity 177, member A1
chr13_+_111767650 0.07 ENST00000449979.1
ENST00000370623.3
 ARHGEF7
 Rho guanine nucleotide exchange factor (GEF) 7
chr3_-_21792838 0.07 ENST00000281523.2
 ZNF385D
 zinc finger protein 385D
chr1_+_110527308 0.07 ENST00000369799.5
 AHCYL1
 adenosylhomocysteinase-like 1
chr17_-_7155802 0.07 ENST00000572043.1
 CTDNEP1
 CTD nuclear envelope phosphatase 1
chr12_+_56511943 0.07 ENST00000257940.2
ENST00000552345.1
ENST00000551880.1
ENST00000546903.1
ENST00000551790.1
 ZC3H10
ESYT1
 zinc finger CCCH-type containing 10
extended synaptotagmin-like protein 1
chr11_+_18416133 0.07 ENST00000227157.4
ENST00000478970.2
ENST00000495052.1
 LDHA
 lactate dehydrogenase A
chr4_-_76598544 0.07 ENST00000515457.1
ENST00000357854.3
 G3BP2
 GTPase activating protein (SH3 domain) binding protein 2
chr17_+_4643337 0.07 ENST00000592813.1
 ZMYND15
 zinc finger, MYND-type containing 15
chr17_+_4802713 0.07 ENST00000521575.1
ENST00000381365.3
 C17orf107
 chromosome 17 open reading frame 107
chr11_+_18416103 0.07 ENST00000543445.1
ENST00000430553.2
ENST00000396222.2
ENST00000535451.1
 LDHA
 lactate dehydrogenase A
chr11_+_18344106 0.07 ENST00000534641.1
ENST00000525831.1
ENST00000265963.4
 GTF2H1
 general transcription factor IIH, polypeptide 1, 62kDa
chr17_+_41177220 0.07 ENST00000587250.2
ENST00000544533.1
 RND2
 Rho family GTPase 2
chr21_-_40720995 0.07 ENST00000380749.5
 HMGN1
 high mobility group nucleosome binding domain 1
chr19_-_9649253 0.07 ENST00000593003.1
 ZNF426
 zinc finger protein 426
chr9_-_70490107 0.07 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
 CBWD5
 COBW domain containing 5
chr6_-_121655552 0.07 ENST00000275159.6
 TBC1D32
 TBC1 domain family, member 32
chr8_+_98788003 0.07 ENST00000521545.2
 LAPTM4B
 lysosomal protein transmembrane 4 beta
chr2_+_114195268 0.07 ENST00000259199.4
ENST00000416503.2
ENST00000433343.2
 CBWD2
 COBW domain containing 2
chr12_-_31881944 0.07 ENST00000537562.1
ENST00000537960.1
ENST00000536761.1
ENST00000542781.1
ENST00000457428.2
 AMN1
 antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr12_-_31882027 0.07 ENST00000541931.1
ENST00000535408.1
 AMN1
 antagonist of mitotic exit network 1 homolog (S. cerevisiae)
chr1_-_22109682 0.07 ENST00000400301.1
ENST00000532737.1
 USP48
 ubiquitin specific peptidase 48
chr12_-_5352315 0.07 ENST00000536518.1
 RP11-319E16.1
 RP11-319E16.1
chr19_-_44100275 0.06 ENST00000422989.1
ENST00000598324.1
 IRGQ
 immunity-related GTPase family, Q
chr2_-_61389168 0.06 ENST00000607743.1
ENST00000605902.1
 RP11-493E12.1
 RP11-493E12.1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.2 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.2 GO:2000681 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.1 GO:2000118 regulation of sodium-dependent phosphate transport(GO:2000118)
0.0 0.8 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.3 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.1 GO:0017186 peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186)
0.0 0.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.1 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.0 GO:0018963 phthalate metabolic process(GO:0018963)
0.0 0.1 GO:1904640 response to methionine(GO:1904640)
0.0 0.1 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.1 GO:0060382 regulation of DNA strand elongation(GO:0060382)
0.0 0.1 GO:1990180 mitochondrial tRNA 3'-end processing(GO:1990180)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.0 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:0021896 forebrain astrocyte differentiation(GO:0021896) forebrain astrocyte development(GO:0021897) gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.3 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.2 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0046379 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.1 GO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.3 GO:0000050 urea cycle(GO:0000050)
0.0 0.2 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.2 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.1 GO:0035617 stress granule disassembly(GO:0035617)
0.0 0.1 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.0 0.1 GO:2001171 positive regulation of ATP biosynthetic process(GO:2001171)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0035026 leading edge cell differentiation(GO:0035026)
0.0 0.1 GO:2001045 negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.0 GO:1990519 pyrimidine nucleotide transport(GO:0006864) mitochondrial pyrimidine nucleotide import(GO:1990519)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.1 GO:1900368 regulation of RNA interference(GO:1900368)
0.0 0.1 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0 0.2 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.0 0.1 GO:0061084 regulation of protein refolding(GO:0061083) negative regulation of protein refolding(GO:0061084)
0.0 0.4 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0039007 pronephric nephron morphogenesis(GO:0039007) pronephric nephron tubule morphogenesis(GO:0039008) pronephric duct development(GO:0039022) pronephric duct morphogenesis(GO:0039023) Kupffer's vesicle development(GO:0070121)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.0 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.4 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.0 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.0 GO:0021503 neural fold bending(GO:0021503)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.2 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0075341 host cell PML body(GO:0075341)
0.0 0.2 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.1 GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing)(GO:0009330)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.2 GO:0000322 storage vacuole(GO:0000322)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.4 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.0 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.0 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0045155 electron transporter, transferring electrons from CoQH2-cytochrome c reductase complex and cytochrome c oxidase complex activity(GO:0045155)
0.1 0.3 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.2 GO:0032427 GBD domain binding(GO:0032427)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0016603 glutaminyl-peptide cyclotransferase activity(GO:0016603)
0.0 0.2 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.2 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.3 GO:0034485 phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485)
0.0 0.1 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.0 GO:0043849 Ras palmitoyltransferase activity(GO:0043849)
0.0 0.1 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.0 GO:0004108 citrate (Si)-synthase activity(GO:0004108) citrate synthase activity(GO:0036440)
0.0 0.1 GO:0004936 alpha-adrenergic receptor activity(GO:0004936)
0.0 0.0 GO:0051538 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.0 GO:0015218 pyrimidine nucleotide transmembrane transporter activity(GO:0015218)
0.0 0.1 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.0 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.0 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.3 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease