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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for CEBPA

Z-value: 2.10

Motif logo

Transcription factors associated with CEBPA

Gene Symbol Gene ID Gene Info
ENSG00000245848.2 CEBPA

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
CEBPAhg19_v2_chr19_-_33793430_33793470-0.404.4e-01Click!

Activity profile of CEBPA motif

Sorted Z-values of CEBPA motif

Network of associatons between targets according to the STRING database.

First level regulatory network of CEBPA

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr11_-_18270182 3.89 ENST00000528349.1
ENST00000526900.1
ENST00000529528.1
ENST00000414546.2
ENST00000256733.4
SAA2
serum amyloid A2
chr11_-_18258342 3.66 ENST00000278222.4
SAA4
serum amyloid A4, constitutive
chr18_-_61311485 3.19 ENST00000436264.1
ENST00000356424.6
ENST00000341074.5
SERPINB4
serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr11_+_18287721 3.09 ENST00000356524.4
SAA1
serum amyloid A1
chr11_+_18287801 3.08 ENST00000532858.1
ENST00000405158.2
SAA1
serum amyloid A1
chr6_+_31895467 2.93 ENST00000556679.1
ENST00000456570.1
CFB
CFB
complement factor B
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr6_+_31895480 2.74 ENST00000418949.2
ENST00000383177.3
ENST00000477310.1
C2
CFB
complement component 2
Complement factor B; Uncharacterized protein; cDNA FLJ55673, highly similar to Complement factor B
chr2_+_228678550 2.50 ENST00000409189.3
ENST00000358813.4
CCL20
chemokine (C-C motif) ligand 20
chr4_+_74606223 2.50 ENST00000307407.3
ENST00000401931.1
IL8
interleukin 8
chr12_+_72058130 2.25 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chr15_-_80263506 2.20 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr6_-_133055815 2.17 ENST00000509351.1
ENST00000417437.2
ENST00000414302.2
ENST00000423615.2
ENST00000427187.2
ENST00000275223.3
ENST00000519686.2
VNN3
vanin 3
chr6_-_133055896 2.09 ENST00000367927.5
ENST00000425515.2
ENST00000207771.3
ENST00000392393.3
ENST00000450865.2
ENST00000392394.2
VNN3
vanin 3
chr11_-_102668879 2.08 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr1_+_152486950 2.04 ENST00000368790.3
CRCT1
cysteine-rich C-terminal 1
chr19_-_6720686 2.02 ENST00000245907.6
C3
complement component 3
chr1_-_153029980 1.98 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr19_-_6670128 1.97 ENST00000245912.3
TNFSF14
tumor necrosis factor (ligand) superfamily, member 14
chr18_-_61329118 1.69 ENST00000332821.8
ENST00000283752.5
SERPINB3
serpin peptidase inhibitor, clade B (ovalbumin), member 3
chr5_-_150473127 1.68 ENST00000521001.1
TNIP1
TNFAIP3 interacting protein 1
chr1_-_153321301 1.61 ENST00000368739.3
PGLYRP4
peptidoglycan recognition protein 4
chr14_+_95078714 1.60 ENST00000393078.3
ENST00000393080.4
ENST00000467132.1
SERPINA3
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
chr20_+_58630972 1.54 ENST00000313426.1
C20orf197
chromosome 20 open reading frame 197
chr17_-_38859996 1.51 ENST00000264651.2
KRT24
keratin 24
chr9_+_130911723 1.50 ENST00000277480.2
ENST00000373013.2
ENST00000540948.1
LCN2
lipocalin 2
chr20_-_43883197 1.46 ENST00000338380.2
SLPI
secretory leukocyte peptidase inhibitor
chr2_-_113594279 1.35 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
IL1B
interleukin 1, beta
chr1_-_153348067 1.30 ENST00000368737.3
S100A12
S100 calcium binding protein A12
chr12_-_123201337 1.27 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr3_-_4793274 1.25 ENST00000414938.1
EGOT
eosinophil granule ontogeny transcript (non-protein coding)
chr9_+_130911770 1.19 ENST00000372998.1
LCN2
lipocalin 2
chr18_+_61554932 1.07 ENST00000299502.4
ENST00000457692.1
ENST00000413956.1
SERPINB2
serpin peptidase inhibitor, clade B (ovalbumin), member 2
chr2_+_223289208 1.06 ENST00000321276.7
SGPP2
sphingosine-1-phosphate phosphatase 2
chr17_+_67759813 1.06 ENST00000587241.1
AC003051.1
AC003051.1
chr9_+_6215799 1.01 ENST00000417746.2
ENST00000456383.2
IL33
interleukin 33
chr19_-_4540486 0.99 ENST00000306390.6
LRG1
leucine-rich alpha-2-glycoprotein 1
chr1_-_114429997 0.96 ENST00000471267.1
ENST00000393320.3
BCL2L15
BCL2-like 15
chr11_+_107650219 0.91 ENST00000398067.1
AP001024.1
Uncharacterized protein
chr2_+_143635222 0.91 ENST00000375773.2
ENST00000409512.1
ENST00000410015.2
KYNU
kynureninase
chr2_+_143635067 0.90 ENST00000264170.4
KYNU
kynureninase
chr5_+_148443049 0.88 ENST00000515304.1
ENST00000507318.1
CTC-529P8.1
CTC-529P8.1
chr2_-_31637560 0.84 ENST00000379416.3
XDH
xanthine dehydrogenase
chr9_+_99690592 0.83 ENST00000354649.3
NUTM2G
NUT family member 2G
chr6_+_126240442 0.77 ENST00000448104.1
ENST00000438495.1
ENST00000444128.1
NCOA7
nuclear receptor coactivator 7
chr6_+_106534192 0.76 ENST00000369091.2
ENST00000369096.4
PRDM1
PR domain containing 1, with ZNF domain
chr8_+_119294456 0.69 ENST00000366457.2
AC023590.1
Uncharacterized protein
chr10_-_75676400 0.68 ENST00000412307.2
C10orf55
chromosome 10 open reading frame 55
chr15_-_74501310 0.65 ENST00000423167.2
ENST00000432245.2
STRA6
stimulated by retinoic acid 6
chr7_-_112635675 0.63 ENST00000447785.1
ENST00000451962.1
AC018464.3
AC018464.3
chr7_-_107968999 0.63 ENST00000456431.1
NRCAM
neuronal cell adhesion molecule
chr16_-_55866997 0.63 ENST00000360526.3
ENST00000361503.4
CES1
carboxylesterase 1
chr1_+_117544366 0.61 ENST00000256652.4
ENST00000369470.1
CD101
CD101 molecule
chr12_-_123187890 0.60 ENST00000328880.5
HCAR2
hydroxycarboxylic acid receptor 2
chr4_+_71384300 0.59 ENST00000504451.1
AMTN
amelotin
chr11_-_33913708 0.58 ENST00000257818.2
LMO2
LIM domain only 2 (rhombotin-like 1)
chr12_+_7167980 0.56 ENST00000360817.5
ENST00000402681.3
C1S
complement component 1, s subcomponent
chr22_-_30901637 0.56 ENST00000381982.3
ENST00000255858.7
ENST00000540456.1
ENST00000392772.2
SEC14L4
SEC14-like 4 (S. cerevisiae)
chr1_+_209941942 0.56 ENST00000487271.1
ENST00000477431.1
TRAF3IP3
TRAF3 interacting protein 3
chr4_+_75230853 0.56 ENST00000244869.2
EREG
epiregulin
chr1_-_193075180 0.55 ENST00000367440.3
GLRX2
glutaredoxin 2
chr3_+_157154578 0.54 ENST00000295927.3
PTX3
pentraxin 3, long
chr14_+_39703112 0.54 ENST00000555143.1
ENST00000280082.3
MIA2
melanoma inhibitory activity 2
chr14_-_21516590 0.54 ENST00000555026.1
NDRG2
NDRG family member 2
chr7_-_92777606 0.53 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L
sterile alpha motif domain containing 9-like
chr16_+_82090028 0.53 ENST00000568090.1
HSD17B2
hydroxysteroid (17-beta) dehydrogenase 2
chr1_-_186649543 0.53 ENST00000367468.5
PTGS2
prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
chr2_-_61389240 0.52 ENST00000606876.1
RP11-493E12.1
RP11-493E12.1
chr21_-_46348694 0.51 ENST00000355153.4
ENST00000397850.2
ITGB2
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)
chr5_-_121413974 0.49 ENST00000231004.4
LOX
lysyl oxidase
chr17_-_47925379 0.49 ENST00000352793.2
ENST00000334568.4
ENST00000398154.1
ENST00000436235.1
ENST00000326219.5
TAC4
tachykinin 4 (hemokinin)
chr8_+_107593198 0.49 ENST00000517686.1
OXR1
oxidation resistance 1
chr11_-_60010556 0.48 ENST00000427611.2
MS4A4E
membrane-spanning 4-domains, subfamily A, member 4E
chr10_-_69597828 0.48 ENST00000339758.7
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr1_-_200992827 0.48 ENST00000332129.2
ENST00000422435.2
KIF21B
kinesin family member 21B
chr1_+_169079823 0.48 ENST00000367813.3
ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr7_+_26191809 0.47 ENST00000056233.3
NFE2L3
nuclear factor, erythroid 2-like 3
chr6_+_126102292 0.46 ENST00000368357.3
NCOA7
nuclear receptor coactivator 7
chr17_-_72619869 0.46 ENST00000392619.1
ENST00000426295.2
CD300E
CD300e molecule
chr3_-_148939598 0.45 ENST00000455472.3
CP
ceruloplasmin (ferroxidase)
chr1_-_156721502 0.44 ENST00000357325.5
HDGF
hepatoma-derived growth factor
chr2_+_28618532 0.44 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr8_+_55471630 0.44 ENST00000522001.1
RP11-53M11.3
RP11-53M11.3
chr6_+_53964336 0.44 ENST00000447836.2
ENST00000511678.1
MLIP
muscular LMNA-interacting protein
chr4_+_71384257 0.44 ENST00000339336.4
AMTN
amelotin
chr1_-_114430169 0.44 ENST00000393316.3
BCL2L15
BCL2-like 15
chr14_+_77582905 0.44 ENST00000557408.1
TMEM63C
transmembrane protein 63C
chrY_-_20935572 0.43 ENST00000382852.1
ENST00000344884.4
ENST00000304790.3
HSFY2
heat shock transcription factor, Y linked 2
chr17_-_79895097 0.43 ENST00000402252.2
ENST00000583564.1
ENST00000585244.1
ENST00000337943.5
ENST00000579698.1
PYCR1
pyrroline-5-carboxylate reductase 1
chr9_+_27524283 0.41 ENST00000276943.2
IFNK
interferon, kappa
chr2_-_225362533 0.41 ENST00000451538.1
CUL3
cullin 3
chr12_+_27849378 0.40 ENST00000310791.2
REP15
RAB15 effector protein
chr8_-_71157595 0.40 ENST00000519724.1
NCOA2
nuclear receptor coactivator 2
chr18_-_68004529 0.39 ENST00000578633.1
RP11-484N16.1
RP11-484N16.1
chr1_-_198906528 0.39 ENST00000432296.1
MIR181A1HG
MIR181A1 host gene (non-protein coding)
chrY_+_20708557 0.39 ENST00000307393.2
ENST00000309834.4
ENST00000382856.2
HSFY1
heat shock transcription factor, Y-linked 1
chr4_+_186347388 0.38 ENST00000511138.1
ENST00000511581.1
C4orf47
chromosome 4 open reading frame 47
chr15_-_74501360 0.38 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr5_-_159739532 0.36 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL
cyclin J-like
chr13_+_78109804 0.36 ENST00000535157.1
SCEL
sciellin
chr3_-_129375556 0.35 ENST00000510323.1
TMCC1
transmembrane and coiled-coil domain family 1
chr8_+_118533049 0.35 ENST00000522839.1
MED30
mediator complex subunit 30
chr6_+_31895254 0.35 ENST00000299367.5
ENST00000442278.2
C2
complement component 2
chr2_-_18770802 0.34 ENST00000416783.1
NT5C1B
5'-nucleotidase, cytosolic IB
chr2_-_220119280 0.34 ENST00000392088.2
TUBA4A
tubulin, alpha 4a
chr3_-_158450231 0.34 ENST00000479756.1
RARRES1
retinoic acid receptor responder (tazarotene induced) 1
chr17_-_73840614 0.34 ENST00000586108.1
UNC13D
unc-13 homolog D (C. elegans)
chr14_-_70263979 0.34 ENST00000216540.4
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr18_-_56985776 0.34 ENST00000587244.1
CPLX4
complexin 4
chr3_+_171844762 0.34 ENST00000443501.1
FNDC3B
fibronectin type III domain containing 3B
chr13_+_111267866 0.34 ENST00000458711.2
ENST00000424185.2
ENST00000397191.4
ENST00000309957.2
CARKD
carbohydrate kinase domain containing
chr10_-_45474237 0.33 ENST00000448778.1
ENST00000298295.3
C10orf10
chromosome 10 open reading frame 10
chrX_+_49019061 0.33 ENST00000376339.1
ENST00000425661.2
ENST00000458388.1
ENST00000412696.2
MAGIX
MAGI family member, X-linked
chr9_+_134001455 0.32 ENST00000531584.1
NUP214
nucleoporin 214kDa
chr19_-_50083822 0.32 ENST00000596358.1
NOSIP
nitric oxide synthase interacting protein
chr1_-_26633480 0.32 ENST00000450041.1
UBXN11
UBX domain protein 11
chrX_-_71525742 0.32 ENST00000450875.1
ENST00000417400.1
ENST00000431381.1
ENST00000445983.1
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr11_-_85397167 0.32 ENST00000316398.3
CCDC89
coiled-coil domain containing 89
chr17_-_79895154 0.31 ENST00000405481.4
ENST00000585215.1
ENST00000577624.1
ENST00000403172.4
PYCR1
pyrroline-5-carboxylate reductase 1
chr1_+_165797024 0.31 ENST00000372212.4
UCK2
uridine-cytidine kinase 2
chr22_+_46481861 0.31 ENST00000360737.3
FLJ27365
hsa-mir-4763
chr12_+_88429223 0.30 ENST00000356891.3
C12orf29
chromosome 12 open reading frame 29
chr3_+_118892411 0.30 ENST00000479520.1
ENST00000494855.1
UPK1B
uroplakin 1B
chr13_+_96085847 0.29 ENST00000376873.3
CLDN10
claudin 10
chr12_-_95510743 0.29 ENST00000551521.1
FGD6
FYVE, RhoGEF and PH domain containing 6
chr13_-_20805109 0.28 ENST00000241124.6
GJB6
gap junction protein, beta 6, 30kDa
chr5_-_145483932 0.28 ENST00000311450.4
PLAC8L1
PLAC8-like 1
chr20_-_1600642 0.28 ENST00000381603.3
ENST00000381605.4
ENST00000279477.7
ENST00000568365.1
ENST00000564763.1
SIRPB1
RP4-576H24.4
signal-regulatory protein beta 1
Uncharacterized protein
chrX_-_68385354 0.28 ENST00000361478.1
PJA1
praja ring finger 1, E3 ubiquitin protein ligase
chr2_-_175711978 0.28 ENST00000409089.2
CHN1
chimerin 1
chr18_-_5396271 0.27 ENST00000579951.1
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr9_+_133569108 0.27 ENST00000372358.5
ENST00000546165.1
ENST00000372352.3
ENST00000372351.3
ENST00000372350.3
ENST00000495699.2
EXOSC2
exosome component 2
chr19_+_49497121 0.26 ENST00000413176.2
RUVBL2
RuvB-like AAA ATPase 2
chr5_+_156887027 0.26 ENST00000435489.2
ENST00000311946.7
NIPAL4
NIPA-like domain containing 4
chr15_-_93199069 0.26 ENST00000327355.5
FAM174B
family with sequence similarity 174, member B
chr14_+_72064945 0.26 ENST00000537413.1
SIPA1L1
signal-induced proliferation-associated 1 like 1
chr19_+_49496782 0.26 ENST00000601968.1
ENST00000596837.1
RUVBL2
RuvB-like AAA ATPase 2
chr19_+_51897742 0.26 ENST00000600765.1
CTD-2616J11.14
CTD-2616J11.14
chr14_-_24610779 0.26 ENST00000560403.1
ENST00000419198.2
ENST00000216799.4
EMC9
ER membrane protein complex subunit 9
chr22_-_22307199 0.25 ENST00000397495.4
ENST00000263212.5
PPM1F
protein phosphatase, Mg2+/Mn2+ dependent, 1F
chr7_-_56101826 0.25 ENST00000421626.1
PSPH
phosphoserine phosphatase
chr14_+_101299520 0.25 ENST00000455531.1
MEG3
maternally expressed 3 (non-protein coding)
chr12_+_24857397 0.25 ENST00000536131.1
RP11-625L16.1
RP11-625L16.1
chr5_-_16742330 0.25 ENST00000505695.1
ENST00000427430.2
MYO10
myosin X
chr7_+_100271446 0.25 ENST00000419828.1
ENST00000427895.1
GNB2
guanine nucleotide binding protein (G protein), beta polypeptide 2
chr8_+_38065104 0.24 ENST00000521311.1
BAG4
BCL2-associated athanogene 4
chr12_+_110906169 0.24 ENST00000377673.5
FAM216A
family with sequence similarity 216, member A
chr8_+_9009296 0.24 ENST00000521718.1
RP11-10A14.4
Uncharacterized protein
chr2_-_191885686 0.24 ENST00000432058.1
STAT1
signal transducer and activator of transcription 1, 91kDa
chr19_+_49496705 0.24 ENST00000595090.1
RUVBL2
RuvB-like AAA ATPase 2
chrX_-_100129128 0.24 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1
NADPH oxidase 1
chr21_+_43619796 0.24 ENST00000398457.2
ABCG1
ATP-binding cassette, sub-family G (WHITE), member 1
chr1_-_89531041 0.24 ENST00000370473.4
GBP1
guanylate binding protein 1, interferon-inducible
chr7_+_137761167 0.24 ENST00000432161.1
AKR1D1
aldo-keto reductase family 1, member D1
chrX_-_20236970 0.24 ENST00000379548.4
RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr6_+_76330355 0.24 ENST00000483859.2
SENP6
SUMO1/sentrin specific peptidase 6
chr13_+_78109884 0.24 ENST00000377246.3
ENST00000349847.3
SCEL
sciellin
chr3_-_47517302 0.23 ENST00000441517.2
ENST00000545718.1
SCAP
SREBF chaperone
chr2_-_31440377 0.23 ENST00000444918.2
ENST00000403897.3
CAPN14
calpain 14
chr15_-_89878025 0.23 ENST00000268124.5
ENST00000442287.2
POLG
polymerase (DNA directed), gamma
chrX_+_77359726 0.23 ENST00000442431.1
PGK1
phosphoglycerate kinase 1
chr21_+_34775181 0.23 ENST00000290219.6
IFNGR2
interferon gamma receptor 2 (interferon gamma transducer 1)
chr6_+_30848557 0.23 ENST00000460944.2
ENST00000324771.8
DDR1
discoidin domain receptor tyrosine kinase 1
chr7_+_137761199 0.23 ENST00000411726.2
AKR1D1
aldo-keto reductase family 1, member D1
chr5_+_149980622 0.23 ENST00000394243.1
SYNPO
synaptopodin
chr2_-_70409953 0.22 ENST00000419381.1
C2orf42
chromosome 2 open reading frame 42
chrX_+_15767971 0.22 ENST00000479740.1
ENST00000454127.2
CA5B
carbonic anhydrase VB, mitochondrial
chr1_-_243326612 0.22 ENST00000492145.1
ENST00000490813.1
ENST00000464936.1
CEP170
centrosomal protein 170kDa
chr7_-_14026063 0.22 ENST00000443608.1
ENST00000438956.1
ETV1
ets variant 1
chr3_+_136649311 0.22 ENST00000469404.1
ENST00000467911.1
NCK1
NCK adaptor protein 1
chr2_+_65663812 0.22 ENST00000606978.1
ENST00000377977.3
ENST00000536804.1
AC074391.1
AC074391.1
chr5_+_125758813 0.22 ENST00000285689.3
ENST00000515200.1
GRAMD3
GRAM domain containing 3
chr9_-_117568365 0.22 ENST00000374045.4
TNFSF15
tumor necrosis factor (ligand) superfamily, member 15
chr19_-_50083803 0.21 ENST00000391853.3
ENST00000339093.3
NOSIP
nitric oxide synthase interacting protein
chr21_-_32119551 0.21 ENST00000333892.2
KRTAP21-2
keratin associated protein 21-2
chrX_-_84363974 0.21 ENST00000395409.3
ENST00000332921.5
ENST00000509231.1
SATL1
spermidine/spermine N1-acetyl transferase-like 1
chr16_+_28889801 0.21 ENST00000395503.4
ATP2A1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr21_+_33671264 0.21 ENST00000339944.4
MRAP
melanocortin 2 receptor accessory protein
chr3_+_124303512 0.21 ENST00000454902.1
KALRN
kalirin, RhoGEF kinase
chr1_-_163172625 0.21 ENST00000527988.1
ENST00000531476.1
ENST00000530507.1
RGS5
regulator of G-protein signaling 5
chr16_+_56969284 0.21 ENST00000568358.1
HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr16_-_67881588 0.21 ENST00000561593.1
ENST00000565114.1
CENPT
centromere protein T
chr19_-_49496557 0.20 ENST00000323798.3
ENST00000541188.1
ENST00000544287.1
ENST00000540532.1
ENST00000263276.6
GYS1
glycogen synthase 1 (muscle)
chr7_+_107224364 0.20 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr12_-_91573249 0.20 ENST00000550099.1
ENST00000546391.1
ENST00000551354.1
DCN
decorin
chr6_+_151561085 0.20 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr1_+_152691998 0.20 ENST00000368775.2
C1orf68
chromosome 1 open reading frame 68
chr12_-_71551652 0.20 ENST00000546561.1
TSPAN8
tetraspanin 8
chr9_+_139871948 0.20 ENST00000224167.2
ENST00000457950.1
ENST00000371625.3
ENST00000371623.3
PTGDS
prostaglandin D2 synthase 21kDa (brain)
chr9_-_128246769 0.20 ENST00000444226.1
MAPKAP1
mitogen-activated protein kinase associated protein 1
chr13_+_24144796 0.20 ENST00000403372.2
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr1_-_17380630 0.20 ENST00000375499.3
SDHB
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr11_-_128737259 0.20 ENST00000440599.2
ENST00000392666.1
ENST00000324036.3
KCNJ1
potassium inwardly-rectifying channel, subfamily J, member 1
chr10_+_17272608 0.19 ENST00000421459.2
VIM
vimentin
chr12_+_57623907 0.19 ENST00000553529.1
ENST00000554310.1
SHMT2
serine hydroxymethyltransferase 2 (mitochondrial)
chr19_+_50084561 0.19 ENST00000246794.5
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chr16_+_532503 0.19 ENST00000412256.1
RAB11FIP3
RAB11 family interacting protein 3 (class II)
chr7_+_18536090 0.19 ENST00000441986.1
HDAC9
histone deacetylase 9
chr13_-_45775162 0.19 ENST00000405872.1
KCTD4
potassium channel tetramerization domain containing 4
chr14_+_29241910 0.19 ENST00000399387.4
ENST00000552957.1
ENST00000548213.1
C14orf23
chromosome 14 open reading frame 23
chr19_-_3985455 0.19 ENST00000309311.6
EEF2
eukaryotic translation elongation factor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.8 2.5 GO:0045362 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.7 2.0 GO:0002894 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.6 1.8 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.5 2.7 GO:0015688 iron chelate transport(GO:0015688) siderophore transport(GO:0015891)
0.5 1.6 GO:0051714 positive regulation of cytolysis in other organism(GO:0051714)
0.4 1.7 GO:0035425 autocrine signaling(GO:0035425)
0.4 2.0 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.3 1.7 GO:0085032 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.3 5.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.3 1.9 GO:0031622 regulation of fever generation(GO:0031620) positive regulation of fever generation(GO:0031622)
0.3 0.8 GO:1990654 sebum secreting cell proliferation(GO:1990654)
0.2 3.8 GO:0015939 pantothenate metabolic process(GO:0015939)
0.2 0.8 GO:0046110 xanthine metabolic process(GO:0046110)
0.2 12.5 GO:0006953 acute-phase response(GO:0006953)
0.2 1.0 GO:0061143 alveolar primary septum development(GO:0061143)
0.2 0.6 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.2 0.8 GO:0090202 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.1 1.0 GO:0042488 positive regulation of odontogenesis of dentin-containing tooth(GO:0042488) positive regulation of tooth mineralization(GO:0070172)
0.1 0.5 GO:0001878 response to yeast(GO:0001878)
0.1 0.4 GO:1904017 cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.6 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 1.0 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.1 0.5 GO:0002432 granuloma formation(GO:0002432)
0.1 0.5 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.3 GO:0014724 regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.1 0.7 GO:0055129 L-proline biosynthetic process(GO:0055129)
0.1 0.6 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.8 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 0.4 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.5 GO:0046878 positive regulation of saliva secretion(GO:0046878)
0.1 0.6 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.2 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.1 1.7 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.1 0.2 GO:1903676 regulation of cap-dependent translational initiation(GO:1903674) positive regulation of cap-dependent translational initiation(GO:1903676)
0.1 0.2 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.5 GO:0044861 protein transport into plasma membrane raft(GO:0044861) positive regulation of calcium:sodium antiporter activity(GO:1903281) positive regulation of potassium ion import(GO:1903288)
0.1 0.5 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1 0.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.2 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.1 0.2 GO:0045113 regulation of integrin biosynthetic process(GO:0045113) positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.2 GO:0050955 thermoception(GO:0050955)
0.1 2.1 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.4 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.2 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.3 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.4 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.1 0.6 GO:0042262 DNA protection(GO:0042262)
0.0 0.2 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0044205 'de novo' UMP biosynthetic process(GO:0044205)
0.0 0.2 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.0 0.2 GO:0015742 alpha-ketoglutarate transport(GO:0015742)
0.0 1.7 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590) regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.3 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.2 GO:0015965 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.2 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 1.3 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:0003051 brain renin-angiotensin system(GO:0002035) angiotensin-mediated drinking behavior(GO:0003051) positive regulation of gap junction assembly(GO:1903598)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.7 GO:0006670 sphingosine metabolic process(GO:0006670)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.5 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.5 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.5 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.3 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.2 GO:0090234 regulation of kinetochore assembly(GO:0090234)
0.0 1.0 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:1903625 negative regulation of sperm motility(GO:1901318) negative regulation of DNA catabolic process(GO:1903625) regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.5 GO:0090361 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.1 GO:1990828 response to putrescine(GO:1904585) cellular response to putrescine(GO:1904586) hepatocyte dedifferentiation(GO:1990828)
0.0 0.2 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.1 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.0 0.5 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.5 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.3 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.2 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 1.0 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 1.6 GO:0018149 peptide cross-linking(GO:0018149)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.2 GO:0046952 ketone body catabolic process(GO:0046952)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.3 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.7 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.6 GO:0042789 mRNA transcription from RNA polymerase II promoter(GO:0042789)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.3 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.2 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0070301 cellular response to hydrogen peroxide(GO:0070301)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0072343 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229) negative regulation of pancreatic stellate cell proliferation(GO:2000230)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0090650 rRNA transport(GO:0051029) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.2 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0030806 negative regulation of cyclic nucleotide catabolic process(GO:0030806) negative regulation of cAMP catabolic process(GO:0030821) negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.2 GO:0070543 response to linoleic acid(GO:0070543) blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334)
0.0 0.1 GO:0035377 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.0 GO:1904640 response to methionine(GO:1904640)
0.0 0.2 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0046549 retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.1 GO:0098912 membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912) positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.2 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 13.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.1 0.8 GO:0070552 BRISC complex(GO:0070552)
0.1 0.2 GO:0097444 spine apparatus(GO:0097444)
0.1 0.8 GO:0097255 R2TP complex(GO:0097255)
0.1 0.3 GO:1990876 cytoplasmic side of nuclear pore(GO:1990876)
0.1 0.5 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 9.5 GO:0072562 blood microparticle(GO:0072562)
0.1 0.2 GO:0042565 nuclear RNA export factor complex(GO:0042272) RNA nuclear export complex(GO:0042565)
0.0 0.2 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.4 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 3.0 GO:0035580 specific granule lumen(GO:0035580)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0031213 RSF complex(GO:0031213)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 1.6 GO:0001533 cornified envelope(GO:0001533)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 1.0 GO:0005605 basal lamina(GO:0005605)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.3 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 3.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.6 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.3 GO:0043194 axon initial segment(GO:0043194)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 1.7 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0016234 inclusion body(GO:0016234)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.3 GO:0017159 pantetheine hydrolase activity(GO:0017159)
0.8 2.5 GO:0031731 CCR6 chemokine receptor binding(GO:0031731)
0.4 1.6 GO:0008745 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745)
0.3 1.8 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.3 13.7 GO:0042056 chemoattractant activity(GO:0042056)
0.2 6.7 GO:0001848 complement binding(GO:0001848)
0.1 0.4 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
0.1 0.6 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 0.7 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.5 GO:0050473 arachidonate 15-lipoxygenase activity(GO:0050473)
0.1 2.2 GO:0051400 BH domain binding(GO:0051400)
0.1 0.8 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.8 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.1 0.5 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
0.1 1.3 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.8 GO:0004793 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.8 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.4 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.4 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.1 0.2 GO:0004145 diamine N-acetyltransferase activity(GO:0004145) polyamine binding(GO:0019808)
0.1 0.2 GO:0031780 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.6 GO:0030613 oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614)
0.1 0.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.2 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 1.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.5 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 6.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.3 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.0 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.2 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.2 GO:0030375 thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 2.0 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.2 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.0 0.4 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 1.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.3 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.3 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.0 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.2 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.1 GO:0004906 interferon-gamma receptor activity(GO:0004906)
0.0 4.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.5 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0033878 hormone-sensitive lipase activity(GO:0033878)
0.0 0.1 GO:0033691 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828) sialic acid binding(GO:0033691)
0.0 0.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.2 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 1.0 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0005260 channel-conductance-controlling ATPase activity(GO:0005260)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.8 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.7 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.1 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.3 GO:0005388 calcium-transporting ATPase activity(GO:0005388)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 6.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 2.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 1.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 1.6 PID IL27 PATHWAY IL27-mediated signaling events
0.0 2.1 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 6.7 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.8 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 2.1 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 4.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 1.2 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.7 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.2 7.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.1 2.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 4.5 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 1.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.5 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.5 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.6 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.2 REACTOME REVERSIBLE HYDRATION OF CARBON DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.6 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.4 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.6 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels