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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for CDX2
Z-value: 0.32
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Transcription factors associated with CDX2
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CDX2 | hg19_v2_chr13_-_28545276_28545276 | -0.87 | 2.3e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr6_+_26156551 Show fit | 0.26 |
ENST00000304218.3
|
histone cluster 1, H1e |
|
| chr4_-_48683188 Show fit | 0.19 |
ENST00000505759.1
|
FRY-like |
|
| chr6_-_26189304 Show fit | 0.17 |
ENST00000340756.2
|
histone cluster 1, H4d |
|
| chr8_-_73793975 Show fit | 0.16 |
ENST00000523881.1
|
RP11-1145L24.1 |
|
| chr11_+_86748957 Show fit | 0.16 |
ENST00000526733.1
ENST00000532959.1 |
transmembrane protein 135 |
|
| chr16_-_25122735 Show fit | 0.15 |
ENST00000563176.1
|
RP11-449H11.1 |
|
| chr9_-_95055923 Show fit | 0.13 |
ENST00000430417.1
|
isoleucyl-tRNA synthetase |
|
| chr8_+_145215928 Show fit | 0.12 |
ENST00000528919.1
|
maestro heat-like repeat family member 1 |
|
| chr5_+_136070614 Show fit | 0.12 |
ENST00000502421.1
|
CTB-1I21.1 |
|
| chr14_+_39944025 Show fit | 0.11 |
ENST00000554328.1
ENST00000556620.1 ENST00000557197.1 |
RP11-111A21.1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of CDX2
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0098532 | histone H3-K27 trimethylation(GO:0098532) |
| 0.0 | 0.1 | GO:1904017 | cellular response to Thyroglobulin triiodothyronine(GO:1904017) |
| 0.0 | 0.1 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
| 0.0 | 0.1 | GO:0031291 | Ran protein signal transduction(GO:0031291) |
| 0.0 | 0.1 | GO:0002636 | positive regulation of germinal center formation(GO:0002636) B cell costimulation(GO:0031296) |
| 0.0 | 0.1 | GO:0009212 | dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) |
| 0.0 | 0.0 | GO:0000349 | generation of catalytic spliceosome for first transesterification step(GO:0000349) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0000788 | nuclear nucleosome(GO:0000788) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | GO:0032564 | adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564) |
| 0.0 | 0.1 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
| 0.0 | 0.1 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
| 0.0 | 0.1 | GO:0030375 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
| 0.0 | 0.1 | GO:0001517 | N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) |
| 0.0 | 0.0 | GO:0070119 | ciliary neurotrophic factor binding(GO:0070119) |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.3 | REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION | Genes involved in Apoptosis induced DNA fragmentation |