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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)
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Results for CBFB
Z-value: 0.29
Motif logo
Transcription factors associated with CBFB
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
|
CBFB
|
ENSG00000067955.9 | core-binding factor subunit beta |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| CBFB | hg19_v2_chr16_+_67063142_67063153 | 1.00 | 1.1e-05 | Click! |
Activity profile of CBFB motif
Sorted Z-values of CBFB motif
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr11_+_114310237 | 0.18 |
ENST00000539119.1
|
REXO2
|
RNA exonuclease 2 |
| chr4_-_156297949 | 0.15 |
ENST00000515654.1
|
MAP9
|
microtubule-associated protein 9 |
| chr14_-_24977457 | 0.13 |
ENST00000250378.3
ENST00000206446.4 |
CMA1
|
chymase 1, mast cell |
| chr4_+_88896819 | 0.13 |
ENST00000237623.7
ENST00000395080.3 ENST00000508233.1 ENST00000360804.4 |
SPP1
|
secreted phosphoprotein 1 |
| chr14_-_35183886 | 0.12 |
ENST00000298159.6
|
CFL2
|
cofilin 2 (muscle) |
| chr7_+_7196565 | 0.12 |
ENST00000429911.1
|
C1GALT1
|
core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1 |
| chr3_+_98482175 | 0.11 |
ENST00000485391.1
ENST00000492254.1 |
ST3GAL6
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| chr21_-_36421535 | 0.11 |
ENST00000416754.1
ENST00000437180.1 ENST00000455571.1 |
RUNX1
|
runt-related transcription factor 1 |
| chr17_+_32582293 | 0.11 |
ENST00000580907.1
ENST00000225831.4 |
CCL2
|
chemokine (C-C motif) ligand 2 |
| chr17_+_75316336 | 0.11 |
ENST00000591934.1
|
SEPT9
|
septin 9 |
| chr21_-_36421626 | 0.10 |
ENST00000300305.3
|
RUNX1
|
runt-related transcription factor 1 |
| chr11_+_114310164 | 0.08 |
ENST00000544196.1
ENST00000539754.1 ENST00000539275.1 |
REXO2
|
RNA exonuclease 2 |
| chr5_+_67576109 | 0.08 |
ENST00000522084.1
|
PIK3R1
|
phosphoinositide-3-kinase, regulatory subunit 1 (alpha) |
| chr11_-_9781068 | 0.08 |
ENST00000500698.1
|
RP11-540A21.2
|
RP11-540A21.2 |
| chr6_-_113953705 | 0.07 |
ENST00000452675.1
|
RP11-367G18.1
|
RP11-367G18.1 |
| chr2_-_87248975 | 0.07 |
ENST00000409310.2
ENST00000355705.3 |
PLGLB1
|
plasminogen-like B1 |
| chr15_+_49715449 | 0.07 |
ENST00000560979.1
|
FGF7
|
fibroblast growth factor 7 |
| chr2_+_68592305 | 0.07 |
ENST00000234313.7
|
PLEK
|
pleckstrin |
| chr11_-_18343725 | 0.07 |
ENST00000531848.1
|
HPS5
|
Hermansky-Pudlak syndrome 5 |
| chr1_+_196621156 | 0.06 |
ENST00000359637.2
|
CFH
|
complement factor H |
| chr20_+_43343886 | 0.06 |
ENST00000190983.4
|
WISP2
|
WNT1 inducible signaling pathway protein 2 |
| chr11_+_114310102 | 0.06 |
ENST00000265881.5
|
REXO2
|
RNA exonuclease 2 |
| chr1_-_184723942 | 0.05 |
ENST00000318130.8
|
EDEM3
|
ER degradation enhancer, mannosidase alpha-like 3 |
| chr21_+_35107346 | 0.05 |
ENST00000456489.1
|
ITSN1
|
intersectin 1 (SH3 domain protein) |
| chr11_-_66103867 | 0.05 |
ENST00000424433.2
|
RIN1
|
Ras and Rab interactor 1 |
| chr11_-_66103932 | 0.05 |
ENST00000311320.4
|
RIN1
|
Ras and Rab interactor 1 |
| chr1_+_248058889 | 0.05 |
ENST00000360358.3
|
OR2W3
|
olfactory receptor, family 2, subfamily W, member 3 |
| chr15_+_49715293 | 0.04 |
ENST00000267843.4
ENST00000560270.1 |
FGF7
|
fibroblast growth factor 7 |
| chr1_+_17634689 | 0.04 |
ENST00000375453.1
ENST00000375448.4 |
PADI4
|
peptidyl arginine deiminase, type IV |
| chr8_-_96281419 | 0.04 |
ENST00000286688.5
|
C8orf37
|
chromosome 8 open reading frame 37 |
| chr11_-_18343669 | 0.04 |
ENST00000396253.3
ENST00000349215.3 ENST00000438420.2 |
HPS5
|
Hermansky-Pudlak syndrome 5 |
| chr12_+_25205446 | 0.03 |
ENST00000557489.1
ENST00000354454.3 ENST00000536173.1 |
LRMP
|
lymphoid-restricted membrane protein |
| chrX_-_49041242 | 0.03 |
ENST00000453382.1
ENST00000540849.1 ENST00000536904.1 ENST00000432913.1 |
PRICKLE3
|
prickle homolog 3 (Drosophila) |
| chr2_-_127977654 | 0.03 |
ENST00000409327.1
|
CYP27C1
|
cytochrome P450, family 27, subfamily C, polypeptide 1 |
| chr3_+_98482159 | 0.03 |
ENST00000468553.1
|
ST3GAL6
|
ST3 beta-galactoside alpha-2,3-sialyltransferase 6 |
| chr1_+_196621002 | 0.03 |
ENST00000367429.4
ENST00000439155.2 |
CFH
|
complement factor H |
| chr16_+_53088885 | 0.03 |
ENST00000566029.1
ENST00000447540.1 |
CHD9
|
chromodomain helicase DNA binding protein 9 |
| chr1_-_179112189 | 0.03 |
ENST00000512653.1
ENST00000344730.3 |
ABL2
|
c-abl oncogene 2, non-receptor tyrosine kinase |
| chr9_+_123884038 | 0.03 |
ENST00000373847.1
|
CNTRL
|
centriolin |
| chr12_-_53594227 | 0.03 |
ENST00000550743.2
|
ITGB7
|
integrin, beta 7 |
| chr1_-_179112173 | 0.03 |
ENST00000408940.3
ENST00000504405.1 |
ABL2
|
c-abl oncogene 2, non-receptor tyrosine kinase |
| chr4_+_71091786 | 0.03 |
ENST00000317987.5
|
FDCSP
|
follicular dendritic cell secreted protein |
| chr2_-_158300556 | 0.03 |
ENST00000264192.3
|
CYTIP
|
cytohesin 1 interacting protein |
| chr3_+_157154578 | 0.02 |
ENST00000295927.3
|
PTX3
|
pentraxin 3, long |
| chr14_+_85996471 | 0.02 |
ENST00000330753.4
|
FLRT2
|
fibronectin leucine rich transmembrane protein 2 |
| chr11_-_66104237 | 0.02 |
ENST00000530056.1
|
RIN1
|
Ras and Rab interactor 1 |
| chr1_+_47264711 | 0.02 |
ENST00000371923.4
ENST00000271153.4 ENST00000371919.4 |
CYP4B1
|
cytochrome P450, family 4, subfamily B, polypeptide 1 |
| chr15_-_33447055 | 0.02 |
ENST00000559047.1
ENST00000561249.1 |
FMN1
|
formin 1 |
| chr17_+_1633755 | 0.02 |
ENST00000545662.1
|
WDR81
|
WD repeat domain 81 |
| chr9_+_15422702 | 0.02 |
ENST00000380821.3
ENST00000421710.1 |
SNAPC3
|
small nuclear RNA activating complex, polypeptide 3, 50kDa |
| chr14_-_61116168 | 0.02 |
ENST00000247182.6
|
SIX1
|
SIX homeobox 1 |
| chr14_+_85996507 | 0.02 |
ENST00000554746.1
|
FLRT2
|
fibronectin leucine rich transmembrane protein 2 |
| chr12_-_4754356 | 0.02 |
ENST00000540967.1
|
AKAP3
|
A kinase (PRKA) anchor protein 3 |
| chr22_+_42665742 | 0.02 |
ENST00000332965.3
ENST00000415205.1 ENST00000446578.1 |
Z83851.3
|
Z83851.3 |
| chr15_-_64665911 | 0.02 |
ENST00000606793.1
ENST00000561349.1 ENST00000560278.1 |
CTD-2116N17.1
|
Uncharacterized protein |
| chr19_-_14049184 | 0.02 |
ENST00000339560.5
|
PODNL1
|
podocan-like 1 |
| chr1_+_89246647 | 0.02 |
ENST00000544045.1
|
PKN2
|
protein kinase N2 |
| chr12_-_54778444 | 0.01 |
ENST00000551771.1
|
ZNF385A
|
zinc finger protein 385A |
| chr5_-_137878887 | 0.01 |
ENST00000507939.1
ENST00000572514.1 ENST00000499810.2 ENST00000360541.5 |
ETF1
|
eukaryotic translation termination factor 1 |
| chr8_-_28747424 | 0.01 |
ENST00000523436.1
ENST00000397363.4 ENST00000521777.1 ENST00000520184.1 ENST00000521022.1 |
INTS9
|
integrator complex subunit 9 |
| chr20_+_54987168 | 0.01 |
ENST00000360314.3
|
CASS4
|
Cas scaffolding protein family member 4 |
| chr8_-_28747717 | 0.01 |
ENST00000416984.2
|
INTS9
|
integrator complex subunit 9 |
| chr8_+_67624653 | 0.01 |
ENST00000521198.2
|
SGK3
|
serum/glucocorticoid regulated kinase family, member 3 |
| chr6_+_42847649 | 0.01 |
ENST00000424341.2
ENST00000602561.1 |
RPL7L1
|
ribosomal protein L7-like 1 |
| chr11_-_64885111 | 0.01 |
ENST00000528598.1
ENST00000310597.4 |
ZNHIT2
|
zinc finger, HIT-type containing 2 |
| chr12_+_25205568 | 0.01 |
ENST00000548766.1
ENST00000556887.1 |
LRMP
|
lymphoid-restricted membrane protein |
| chr6_-_34524093 | 0.01 |
ENST00000544425.1
|
SPDEF
|
SAM pointed domain containing ETS transcription factor |
| chr18_-_53089723 | 0.01 |
ENST00000561992.1
ENST00000562512.2 |
TCF4
|
transcription factor 4 |
| chr4_-_156297919 | 0.01 |
ENST00000450097.1
|
MAP9
|
microtubule-associated protein 9 |
| chr2_+_173955327 | 0.01 |
ENST00000422149.1
|
MLTK
|
Mitogen-activated protein kinase kinase kinase MLT |
| chr21_-_36421401 | 0.00 |
ENST00000486278.2
|
RUNX1
|
runt-related transcription factor 1 |
| chr18_-_53089538 | 0.00 |
ENST00000566777.1
|
TCF4
|
transcription factor 4 |
| chr15_+_73976545 | 0.00 |
ENST00000318443.5
ENST00000537340.2 ENST00000318424.5 |
CD276
|
CD276 molecule |
| chr15_-_64386120 | 0.00 |
ENST00000300030.3
|
FAM96A
|
family with sequence similarity 96, member A |
| chr12_-_54778471 | 0.00 |
ENST00000550120.1
ENST00000394313.2 ENST00000547210.1 |
ZNF385A
|
zinc finger protein 385A |
| chr1_-_52499443 | 0.00 |
ENST00000371614.1
|
KTI12
|
KTI12 homolog, chromatin associated (S. cerevisiae) |
| chr5_-_108745689 | 0.00 |
ENST00000361189.2
|
PJA2
|
praja ring finger 2, E3 ubiquitin protein ligase |
| chr19_+_10541462 | 0.00 |
ENST00000293683.5
|
PDE4A
|
phosphodiesterase 4A, cAMP-specific |
Network of associatons between targets according to the STRING database.
First level regulatory network of CBFB
Gene Ontology Analysis
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0050720 | interleukin-1 beta biosynthetic process(GO:0050720) |
| 0.0 | 0.1 | GO:0035937 | estrogen secretion(GO:0035937) estradiol secretion(GO:0035938) regulation of estrogen secretion(GO:2000861) regulation of estradiol secretion(GO:2000864) |
| 0.0 | 0.1 | GO:2000502 | negative regulation of natural killer cell chemotaxis(GO:2000502) |
| 0.0 | 0.1 | GO:0016267 | O-glycan processing, core 1(GO:0016267) |
| 0.0 | 0.1 | GO:0060437 | lung growth(GO:0060437) |
| 0.0 | 0.1 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
| 0.0 | 0.2 | GO:0030854 | positive regulation of granulocyte differentiation(GO:0030854) |
| 0.0 | 0.2 | GO:1902412 | regulation of mitotic cytokinesis(GO:1902412) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0031084 | BLOC-2 complex(GO:0031084) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 0.1 | GO:0016263 | glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase activity(GO:0016263) |
| 0.0 | 0.1 | GO:0052798 | beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798) |