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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for BHLHE22_BHLHA15_BHLHE23

Z-value: 0.15

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Transcription factors associated with BHLHE22_BHLHA15_BHLHE23

Gene Symbol Gene ID Gene Info
ENSG00000180828.1 BHLHE22
ENSG00000180535.3 BHLHA15
ENSG00000125533.4 BHLHE23

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
BHLHA15hg19_v2_chr7_+_97840739_978407860.285.9e-01Click!

Activity profile of BHLHE22_BHLHA15_BHLHE23 motif

Sorted Z-values of BHLHE22_BHLHA15_BHLHE23 motif

Network of associatons between targets according to the STRING database.

First level regulatory network of BHLHE22_BHLHA15_BHLHE23

PNG image of the network

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Promoter Score Transcript Gene Gene Info
chr8_+_38239882 0.13 ENST00000607047.1
RP11-350N15.5
RP11-350N15.5
chr5_-_111312622 0.08 ENST00000395634.3
NREP
neuronal regeneration related protein
chr3_-_129375556 0.07 ENST00000510323.1
TMCC1
transmembrane and coiled-coil domain family 1
chr14_+_32414059 0.05 ENST00000553330.1
RP11-187E13.1
Uncharacterized protein
chrX_+_105855160 0.05 ENST00000372544.2
ENST00000372548.4
CXorf57
chromosome X open reading frame 57
chr8_+_67782984 0.05 ENST00000396592.3
ENST00000422365.2
ENST00000492775.1
MCMDC2
minichromosome maintenance domain containing 2
chr1_+_81106951 0.05 ENST00000443565.1
RP5-887A10.1
RP5-887A10.1
chr15_-_38519066 0.05 ENST00000561320.1
ENST00000561161.1
RP11-346D14.1
RP11-346D14.1
chr1_-_168464875 0.04 ENST00000422253.1
RP5-968D22.3
RP5-968D22.3
chr12_+_41136144 0.04 ENST00000548005.1
ENST00000552248.1
CNTN1
contactin 1
chr20_+_57226841 0.04 ENST00000358029.4
ENST00000361830.3
STX16
syntaxin 16
chr10_-_31288398 0.04 ENST00000538351.2
ZNF438
zinc finger protein 438
chr7_+_116502605 0.04 ENST00000458284.2
ENST00000490693.1
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr8_-_95449155 0.03 ENST00000481490.2
FSBP
fibrinogen silencer binding protein
chr5_-_114631958 0.03 ENST00000395557.4
CCDC112
coiled-coil domain containing 112
chr15_-_98417780 0.03 ENST00000503874.3
LINC00923
long intergenic non-protein coding RNA 923
chr8_-_101724989 0.03 ENST00000517403.1
PABPC1
poly(A) binding protein, cytoplasmic 1
chr12_-_94673956 0.03 ENST00000551941.1
RP11-1105G2.3
Uncharacterized protein
chr7_+_114562909 0.03 ENST00000423503.1
ENST00000427207.1
MDFIC
MyoD family inhibitor domain containing
chr11_-_115127611 0.03 ENST00000545094.1
CADM1
cell adhesion molecule 1
chr5_-_114632307 0.03 ENST00000506442.1
ENST00000379611.5
CCDC112
coiled-coil domain containing 112
chr1_+_186344945 0.03 ENST00000419367.3
ENST00000287859.6
C1orf27
chromosome 1 open reading frame 27
chr15_+_40650408 0.03 ENST00000267889.3
DISP2
dispatched homolog 2 (Drosophila)
chr15_+_65843130 0.03 ENST00000569894.1
PTPLAD1
protein tyrosine phosphatase-like A domain containing 1
chr13_+_28813645 0.02 ENST00000282391.5
PAN3
PAN3 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)
chr7_+_116502527 0.02 ENST00000361183.3
CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr12_-_75723805 0.02 ENST00000409799.1
ENST00000409445.3
CAPS2
calcyphosine 2
chr19_+_18208603 0.02 ENST00000262811.6
MAST3
microtubule associated serine/threonine kinase 3
chr6_-_112115103 0.02 ENST00000462598.3
FYN
FYN oncogene related to SRC, FGR, YES
chr2_-_227050079 0.02 ENST00000423838.1
AC068138.1
AC068138.1
chr7_-_99573677 0.02 ENST00000292401.4
AZGP1
alpha-2-glycoprotein 1, zinc-binding
chr1_-_186344802 0.02 ENST00000451586.1
TPR
translocated promoter region, nuclear basket protein
chr1_+_186344883 0.02 ENST00000367470.3
C1orf27
chromosome 1 open reading frame 27
chrX_+_70798261 0.02 ENST00000373696.3
ACRC
acidic repeat containing
chr5_-_137674000 0.02 ENST00000510119.1
ENST00000513970.1
CDC25C
cell division cycle 25C
chr3_+_62304648 0.02 ENST00000462069.1
ENST00000232519.5
ENST00000465142.1
C3orf14
chromosome 3 open reading frame 14
chr17_+_75316336 0.02 ENST00000591934.1
SEPT9
septin 9
chr4_+_25915896 0.02 ENST00000514384.1
SMIM20
small integral membrane protein 20
chr4_+_74301880 0.02 ENST00000395792.2
ENST00000226359.2
AFP
alpha-fetoprotein
chr7_-_48068643 0.02 ENST00000453192.2
SUN3
Sad1 and UNC84 domain containing 3
chr11_+_94758422 0.02 ENST00000450979.2
KDM4E
lysine (K)-specific demethylase 4E
chr17_+_60758814 0.02 ENST00000579432.1
ENST00000446119.2
MRC2
mannose receptor, C type 2
chr9_+_2158485 0.02 ENST00000417599.1
ENST00000382185.1
ENST00000382183.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_166428839 0.02 ENST00000342316.4
CSRNP3
cysteine-serine-rich nuclear protein 3
chr9_+_2158443 0.02 ENST00000302401.3
ENST00000324954.5
ENST00000423555.1
ENST00000382186.1
SMARCA2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr12_-_95397442 0.01 ENST00000547157.1
ENST00000547986.1
ENST00000327772.2
NDUFA12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr3_-_108672742 0.01 ENST00000261047.3
GUCA1C
guanylate cyclase activator 1C
chrX_+_128913906 0.01 ENST00000356892.3
SASH3
SAM and SH3 domain containing 3
chr3_+_137717571 0.01 ENST00000343735.4
CLDN18
claudin 18
chr3_-_18480260 0.01 ENST00000454909.2
SATB1
SATB homeobox 1
chr2_-_188378368 0.01 ENST00000392365.1
ENST00000435414.1
TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr1_-_98515395 0.01 ENST00000424528.2
MIR137HG
MIR137 host gene (non-protein coding)
chr10_+_5135981 0.01 ENST00000380554.3
AKR1C3
aldo-keto reductase family 1, member C3
chr4_-_113207048 0.01 ENST00000361717.3
TIFA
TRAF-interacting protein with forkhead-associated domain
chr2_+_210444298 0.01 ENST00000445941.1
MAP2
microtubule-associated protein 2
chr7_-_55930443 0.01 ENST00000388975.3
SEPT14
septin 14
chr1_+_12524965 0.01 ENST00000471923.1
VPS13D
vacuolar protein sorting 13 homolog D (S. cerevisiae)
chr19_-_37019562 0.01 ENST00000523638.1
ZNF260
zinc finger protein 260
chrX_-_73061339 0.01 ENST00000602863.1
XIST
X inactive specific transcript (non-protein coding)
chr4_-_141075330 0.01 ENST00000509479.2
MAML3
mastermind-like 3 (Drosophila)
chr2_+_181845763 0.01 ENST00000602499.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chr8_-_38239732 0.01 ENST00000534155.1
ENST00000433384.2
ENST00000317025.8
ENST00000316985.3
WHSC1L1
Wolf-Hirschhorn syndrome candidate 1-like 1
chr17_+_39846114 0.01 ENST00000586699.1
EIF1
eukaryotic translation initiation factor 1
chr12_+_2912363 0.01 ENST00000544366.1
FKBP4
FK506 binding protein 4, 59kDa
chr20_+_33292507 0.01 ENST00000414082.1
TP53INP2
tumor protein p53 inducible nuclear protein 2
chr5_+_173316341 0.01 ENST00000520867.1
ENST00000334035.5
CPEB4
cytoplasmic polyadenylation element binding protein 4
chr18_-_52989525 0.01 ENST00000457482.3
TCF4
transcription factor 4
chr6_-_119031228 0.01 ENST00000392500.3
ENST00000368488.5
ENST00000434604.1
CEP85L
centrosomal protein 85kDa-like
chr2_+_210444748 0.01 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr1_+_47489240 0.01 ENST00000371901.3
CYP4X1
cytochrome P450, family 4, subfamily X, polypeptide 1
chr18_+_32290218 0.01 ENST00000348997.5
ENST00000588949.1
ENST00000597599.1
DTNA
dystrobrevin, alpha
chr10_+_133918175 0.01 ENST00000298622.4
JAKMIP3
Janus kinase and microtubule interacting protein 3
chr4_-_153456153 0.01 ENST00000603548.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr11_+_66008698 0.01 ENST00000531597.1
PACS1
phosphofurin acidic cluster sorting protein 1
chr5_+_135496675 0.01 ENST00000507637.1
SMAD5
SMAD family member 5
chr8_+_67976593 0.01 ENST00000262210.5
ENST00000412460.1
CSPP1
centrosome and spindle pole associated protein 1
chr14_-_69864993 0.01 ENST00000555373.1
ERH
enhancer of rudimentary homolog (Drosophila)
chr2_-_32490801 0.01 ENST00000360906.5
ENST00000342905.6
NLRC4
NLR family, CARD domain containing 4
chr4_-_87028478 0.01 ENST00000515400.1
ENST00000395157.3
MAPK10
mitogen-activated protein kinase 10
chrX_-_13835461 0.01 ENST00000316715.4
ENST00000356942.5
GPM6B
glycoprotein M6B
chr19_-_52227221 0.01 ENST00000222115.1
ENST00000540069.2
HAS1
hyaluronan synthase 1
chr4_+_55095428 0.01 ENST00000508170.1
ENST00000512143.1
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr4_-_159094194 0.01 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B
family with sequence similarity 198, member B
chr2_+_108994466 0.01 ENST00000272452.2
SULT1C4
sulfotransferase family, cytosolic, 1C, member 4
chr3_+_185300270 0.01 ENST00000430355.1
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr15_-_55700522 0.01 ENST00000564092.1
ENST00000310958.6
CCPG1
cell cycle progression 1
chr1_-_205391178 0.01 ENST00000367153.4
ENST00000367151.2
ENST00000391936.2
ENST00000367149.3
LEMD1
LEM domain containing 1
chr3_-_33700589 0.01 ENST00000461133.3
ENST00000496954.2
CLASP2
cytoplasmic linker associated protein 2
chr4_-_41216619 0.01 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr2_+_186603355 0.01 ENST00000343098.5
FSIP2
fibrous sheath interacting protein 2
chr6_-_66417107 0.01 ENST00000370621.3
ENST00000370618.3
ENST00000503581.1
ENST00000393380.2
EYS
eyes shut homolog (Drosophila)
chr3_-_114477962 0.01 ENST00000471418.1
ZBTB20
zinc finger and BTB domain containing 20
chr2_+_181845843 0.01 ENST00000602710.1
UBE2E3
ubiquitin-conjugating enzyme E2E 3
chrX_-_13835147 0.01 ENST00000493677.1
ENST00000355135.2
GPM6B
glycoprotein M6B
chr15_-_55700216 0.01 ENST00000569205.1
CCPG1
cell cycle progression 1
chr8_-_23315131 0.01 ENST00000518718.1
ENTPD4
ectonucleoside triphosphate diphosphohydrolase 4
chr2_-_32490859 0.01 ENST00000404025.2
NLRC4
NLR family, CARD domain containing 4
chr3_-_196911002 0.01 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr4_+_144354644 0.01 ENST00000512843.1
GAB1
GRB2-associated binding protein 1
chr4_-_74088800 0.01 ENST00000509867.2
ANKRD17
ankyrin repeat domain 17
chr5_-_171433819 0.01 ENST00000296933.6
FBXW11
F-box and WD repeat domain containing 11
chr10_+_17794251 0.01 ENST00000377495.1
ENST00000338221.5
TMEM236
transmembrane protein 236
chr3_+_185300391 0.01 ENST00000545472.1
SENP2
SUMO1/sentrin/SMT3 specific peptidase 2
chr3_-_150264272 0.01 ENST00000491660.1
ENST00000487153.1
ENST00000239944.2
SERP1
stress-associated endoplasmic reticulum protein 1
chr7_-_112758665 0.01 ENST00000397764.3
LINC00998
long intergenic non-protein coding RNA 998
chr4_+_154178520 0.01 ENST00000433687.1
TRIM2
tripartite motif containing 2
chr16_-_4896205 0.01 ENST00000589389.1
GLYR1
glyoxylate reductase 1 homolog (Arabidopsis)
chr12_-_91573132 0.01 ENST00000550563.1
ENST00000546370.1
DCN
decorin
chr2_-_182545603 0.01 ENST00000295108.3
NEUROD1
neuronal differentiation 1
chr2_+_234637754 0.01 ENST00000482026.1
ENST00000609767.1
UGT1A3
UGT1A1
UDP glucuronosyltransferase 1 family, polypeptide A3
UDP glucuronosyltransferase 1 family, polypeptide A8
chr3_-_196910721 0.01 ENST00000443183.1
DLG1
discs, large homolog 1 (Drosophila)
chrX_+_120181457 0.00 ENST00000328078.1
GLUD2
glutamate dehydrogenase 2
chr21_-_46086844 0.00 ENST00000360770.3
KRTAP12-2
keratin associated protein 12-2
chr8_-_67976509 0.00 ENST00000518747.1
COPS5
COP9 signalosome subunit 5
chr2_+_219840955 0.00 ENST00000598002.1
ENST00000432733.1
LINC00608
long intergenic non-protein coding RNA 608
chr4_+_2813946 0.00 ENST00000442312.2
SH3BP2
SH3-domain binding protein 2
chr3_+_112930387 0.00 ENST00000485230.1
BOC
BOC cell adhesion associated, oncogene regulated
chr4_+_114214125 0.00 ENST00000509550.1
ANK2
ankyrin 2, neuronal
chr17_-_31404 0.00 ENST00000343572.7
DOC2B
double C2-like domains, beta
chr3_+_137728842 0.00 ENST00000183605.5
CLDN18
claudin 18
chr5_-_171433579 0.00 ENST00000265094.5
ENST00000393802.2
FBXW11
F-box and WD repeat domain containing 11
chr6_+_4087664 0.00 ENST00000430835.2
C6orf201
chromosome 6 open reading frame 201
chr15_-_55700457 0.00 ENST00000442196.3
ENST00000563171.1
ENST00000425574.3
CCPG1
cell cycle progression 1
chr19_-_11450249 0.00 ENST00000222120.3
RAB3D
RAB3D, member RAS oncogene family
chr7_-_48068699 0.00 ENST00000412142.1
ENST00000395572.2
SUN3
Sad1 and UNC84 domain containing 3
chr10_-_69597810 0.00 ENST00000483798.2
DNAJC12
DnaJ (Hsp40) homolog, subfamily C, member 12
chr1_+_100810575 0.00 ENST00000542213.1
CDC14A
cell division cycle 14A
chr8_-_135522425 0.00 ENST00000521673.1
ZFAT
zinc finger and AT hook domain containing
chr7_-_97881429 0.00 ENST00000420697.1
ENST00000379795.3
ENST00000415086.1
ENST00000542604.1
ENST00000447648.2
TECPR1
tectonin beta-propeller repeat containing 1
chr3_-_108672609 0.00 ENST00000393963.3
ENST00000471108.1
GUCA1C
guanylate cyclase activator 1C
chr3_-_18480173 0.00 ENST00000414509.1
SATB1
SATB homeobox 1
chr12_+_50794730 0.00 ENST00000523389.1
ENST00000518561.1
ENST00000347328.5
ENST00000550260.1
LARP4
La ribonucleoprotein domain family, member 4
chr14_-_51297197 0.00 ENST00000382043.4
NIN
ninein (GSK3B interacting protein)
chr17_+_44790515 0.00 ENST00000576346.1
NSF
N-ethylmaleimide-sensitive factor
chr2_+_99953816 0.00 ENST00000289371.6
EIF5B
eukaryotic translation initiation factor 5B
chr14_-_51297837 0.00 ENST00000245441.5
ENST00000389868.3
ENST00000382041.3
ENST00000324330.9
ENST00000453196.1
ENST00000453401.2
NIN
ninein (GSK3B interacting protein)
chrX_+_69509927 0.00 ENST00000374403.3
KIF4A
kinesin family member 4A
chr10_+_51565108 0.00 ENST00000438493.1
ENST00000452682.1
NCOA4
nuclear receptor coactivator 4
chr11_+_94501497 0.00 ENST00000317829.8
ENST00000317837.9
ENST00000433060.2
AMOTL1
angiomotin like 1
chr10_-_15902449 0.00 ENST00000277632.3
FAM188A
family with sequence similarity 188, member A
chr17_-_37009882 0.00 ENST00000378096.3
ENST00000394332.1
ENST00000394333.1
ENST00000577407.1
ENST00000479035.2
RPL23
ribosomal protein L23
chr1_-_99470368 0.00 ENST00000263177.4
LPPR5
Lipid phosphate phosphatase-related protein type 5
chrX_-_15402498 0.00 ENST00000297904.3
FIGF
c-fos induced growth factor (vascular endothelial growth factor D)
chrX_+_107334983 0.00 ENST00000457035.1
ENST00000545696.1
ATG4A
autophagy related 4A, cysteine peptidase
chr3_-_46069223 0.00 ENST00000309285.3
XCR1
chemokine (C motif) receptor 1
chr15_+_63354769 0.00 ENST00000558910.1
TPM1
tropomyosin 1 (alpha)
chrX_+_107334895 0.00 ENST00000372232.3
ENST00000345734.3
ENST00000372254.3
ATG4A
autophagy related 4A, cysteine peptidase
chr3_-_196910477 0.00 ENST00000447466.1
DLG1
discs, large homolog 1 (Drosophila)
chr2_-_228582709 0.00 ENST00000541617.1
ENST00000409456.2
ENST00000409287.1
ENST00000258403.3
SLC19A3
solute carrier family 19 (thiamine transporter), member 3
chr10_+_51565188 0.00 ENST00000430396.2
ENST00000374087.4
ENST00000414907.2
NCOA4
nuclear receptor coactivator 4
chr1_+_180897269 0.00 ENST00000367587.1
KIAA1614
KIAA1614
chr21_-_36421401 0.00 ENST00000486278.2
RUNX1
runt-related transcription factor 1
chrX_+_69509870 0.00 ENST00000374388.3
KIF4A
kinesin family member 4A
chr9_+_18474098 0.00 ENST00000327883.7
ENST00000431052.2
ENST00000380570.4
ADAMTSL1
ADAMTS-like 1
chr1_-_152131703 0.00 ENST00000316073.3
RPTN
repetin
chr9_+_12775011 0.00 ENST00000319264.3
LURAP1L
leucine rich adaptor protein 1-like
chr3_+_113251143 0.00 ENST00000264852.4
ENST00000393830.3
SIDT1
SID1 transmembrane family, member 1
chr3_+_46924829 0.00 ENST00000313049.5
PTH1R
parathyroid hormone 1 receptor
chr4_-_108204904 0.00 ENST00000510463.1
DKK2
dickkopf WNT signaling pathway inhibitor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)