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NHBE cells infected with SARS-CoV-2 Analysis Results (GEO series: GSE147507)

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Results for BACH1_NFE2_NFE2L2

Z-value: 1.13

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Transcription factors associated with BACH1_NFE2_NFE2L2

Gene Symbol Gene ID Gene Info
ENSG00000156273.11 BTB domain and CNC homolog 1
ENSG00000123405.9 nuclear factor, erythroid 2
ENSG00000116044.11 nuclear factor, erythroid 2 like 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
NFE2L2hg19_v2_chr2_-_178129551_178129572-0.843.6e-02Click!
BACH1hg19_v2_chr21_+_30672433_30672464-0.562.5e-01Click!
NFE2hg19_v2_chr12_-_54691668_54691725-0.424.1e-01Click!

Activity profile of BACH1_NFE2_NFE2L2 motif

Sorted Z-values of BACH1_NFE2_NFE2L2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_22766766 4.49 ENST00000426291.1
ENST00000401651.1
ENST00000258743.5
ENST00000420258.2
ENST00000407492.1
ENST00000401630.3
ENST00000406575.1
interleukin 6 (interferon, beta 2)
chr20_+_44637526 1.48 ENST00000372330.3
matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
chr21_+_42742429 1.32 ENST00000418103.1
myxovirus (influenza virus) resistance 2 (mouse)
chr12_-_122238464 0.87 ENST00000546227.1
ras homolog family member F (in filopodia)
chr7_-_127671674 0.78 ENST00000478726.1
leucine rich repeat containing 4
chr16_+_89988259 0.78 ENST00000554444.1
ENST00000556565.1
Tubulin beta-3 chain
chr16_+_47496023 0.60 ENST00000567200.1
phosphorylase kinase, beta
chr10_-_6019552 0.57 ENST00000379977.3
ENST00000397251.3
ENST00000397248.2
interleukin 15 receptor, alpha
chr16_+_30077055 0.55 ENST00000564595.2
ENST00000569798.1
aldolase A, fructose-bisphosphate
chr2_+_113763031 0.54 ENST00000259211.6
interleukin 36, alpha
chr16_-_1429010 0.52 ENST00000513783.1
unkempt family zinc finger-like
chr1_-_109968973 0.52 ENST00000271308.4
ENST00000538610.1
proteasome (prosome, macropain) subunit, alpha type, 5
chr11_-_2924970 0.52 ENST00000533594.1
solute carrier family 22 (organic cation transporter), member 18 antisense
chr8_+_125283924 0.47 ENST00000517482.1
RP11-383J24.1
chr17_-_38859996 0.47 ENST00000264651.2
keratin 24
chr22_-_19466454 0.44 ENST00000494054.1
ubiquitin fusion degradation 1 like (yeast)
chr3_+_14474178 0.43 ENST00000452775.1
solute carrier family 6 (neurotransmitter transporter), member 6
chr1_-_200992827 0.42 ENST00000332129.2
ENST00000422435.2
kinesin family member 21B
chr14_+_103589789 0.40 ENST00000558056.1
ENST00000560869.1
tumor necrosis factor, alpha-induced protein 2
chr14_+_35761540 0.39 ENST00000261479.4
proteasome (prosome, macropain) subunit, alpha type, 6
chr4_+_22999152 0.38 ENST00000511453.1
RP11-412P11.1
chr16_+_30077098 0.37 ENST00000395240.3
ENST00000566846.1
aldolase A, fructose-bisphosphate
chr22_-_19466643 0.36 ENST00000474226.1
ubiquitin fusion degradation 1 like (yeast)
chr2_-_220117867 0.35 ENST00000456818.1
ENST00000447205.1
tubulin, alpha 4a
chr6_-_3157760 0.35 ENST00000333628.3
tubulin, beta 2A class IIa
chr14_-_57197224 0.33 ENST00000554597.1
ENST00000556696.1
Uncharacterized protein
chr1_+_96208646 0.33 ENST00000603401.1
RP11-286B14.2
chr14_+_35761580 0.33 ENST00000553809.1
ENST00000555764.1
ENST00000556506.1
proteasome (prosome, macropain) subunit, alpha type, 6
chr14_-_24732403 0.33 ENST00000206765.6
transglutaminase 1
chr10_-_6019984 0.33 ENST00000525219.2
interleukin 15 receptor, alpha
chr22_-_19466683 0.32 ENST00000399523.1
ENST00000421968.2
ENST00000447868.1
ubiquitin fusion degradation 1 like (yeast)
chr11_-_102668879 0.32 ENST00000315274.6
matrix metallopeptidase 1 (interstitial collagenase)
chr3_+_46204959 0.31 ENST00000357422.2
chemokine (C-C motif) receptor 3
chr12_+_64846129 0.30 ENST00000540417.1
ENST00000539810.1
TANK-binding kinase 1
chr8_-_82395461 0.29 ENST00000256104.4
fatty acid binding protein 4, adipocyte
chr11_+_72983246 0.29 ENST00000393590.2
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr11_-_102826434 0.28 ENST00000340273.4
ENST00000260302.3
matrix metallopeptidase 13 (collagenase 3)
chr16_-_1429627 0.27 ENST00000248104.7
unkempt family zinc finger-like
chr22_-_39636914 0.27 ENST00000381551.4
platelet-derived growth factor beta polypeptide
chr14_-_24732368 0.27 ENST00000544573.1
transglutaminase 1
chr1_+_165796753 0.27 ENST00000367879.4
uridine-cytidine kinase 2
chr8_-_95220775 0.27 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
cadherin 17, LI cadherin (liver-intestine)
chr22_-_19466732 0.26 ENST00000263202.10
ENST00000360834.4
ubiquitin fusion degradation 1 like (yeast)
chr12_+_64845864 0.26 ENST00000538890.1
TANK-binding kinase 1
chr19_-_6670128 0.25 ENST00000245912.3
tumor necrosis factor (ligand) superfamily, member 14
chr1_+_218683438 0.25 ENST00000443836.1
chromosome 1 open reading frame 143
chr17_-_39769005 0.24 ENST00000301653.4
ENST00000593067.1
keratin 16
chr12_+_56075330 0.24 ENST00000394252.3
methyltransferase like 7B
chr16_+_74330673 0.23 ENST00000219313.4
ENST00000540379.1
ENST00000567958.1
ENST00000568615.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr4_-_101111615 0.23 ENST00000273990.2
DNA-damage-inducible transcript 4-like
chr6_+_44214824 0.23 ENST00000371646.5
ENST00000353801.3
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr4_+_79567057 0.22 ENST00000503259.1
ENST00000507802.1
long intergenic non-protein coding RNA 1094
chr9_+_140083099 0.22 ENST00000322310.5
Sjogren syndrome nuclear autoantigen 1
chr14_-_24732738 0.22 ENST00000558074.1
ENST00000560226.1
transglutaminase 1
chr3_+_184016986 0.21 ENST00000417952.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr18_+_68002675 0.21 ENST00000584919.1
Uncharacterized protein
chr11_+_10477733 0.20 ENST00000528723.1
adenosine monophosphate deaminase 3
chr10_+_91087651 0.20 ENST00000371818.4
interferon-induced protein with tetratricopeptide repeats 3
chr21_+_33671264 0.20 ENST00000339944.4
melanocortin 2 receptor accessory protein
chr5_+_35852797 0.19 ENST00000508941.1
interleukin 7 receptor
chr12_+_10365404 0.19 ENST00000266458.5
ENST00000421801.2
ENST00000544284.1
ENST00000545047.1
ENST00000543602.1
ENST00000545887.1
GABA(A) receptor-associated protein like 1
chr4_-_76944621 0.19 ENST00000306602.1
chemokine (C-X-C motif) ligand 10
chr5_-_90610200 0.19 ENST00000511918.1
ENST00000513626.1
ENST00000607854.1
lung cancer associated transcript 1 (non-protein coding)
RP11-213H15.4
chr10_-_71892555 0.19 ENST00000307864.1
apoptosis-inducing factor, mitochondrion-associated, 2
chr19_+_56652643 0.18 ENST00000586123.1
zinc finger protein 444
chr14_-_23504087 0.18 ENST00000493471.2
ENST00000460922.2
proteasome (prosome, macropain) subunit, beta type, 5
chr10_+_69865866 0.18 ENST00000354393.2
myopalladin
chr11_-_67141640 0.18 ENST00000533438.1
cardiotrophin-like cytokine factor 1
chr7_+_139528952 0.17 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
thromboxane A synthase 1 (platelet)
chr7_+_42971799 0.17 ENST00000223324.2
mitochondrial ribosomal protein L32
chr2_+_90248739 0.17 ENST00000468879.1
immunoglobulin kappa variable 1D-43
chr7_+_1084206 0.17 ENST00000444847.1
G protein-coupled receptor 146
chr19_+_50706866 0.17 ENST00000440075.2
ENST00000376970.2
ENST00000425460.1
ENST00000599920.1
ENST00000601313.1
myosin, heavy chain 14, non-muscle
chr6_+_44215603 0.17 ENST00000371554.1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr22_+_19466980 0.17 ENST00000407835.1
ENST00000438587.1
cell division cycle 45
chr2_+_201987200 0.17 ENST00000425030.1
CASP8 and FADD-like apoptosis regulator
chr5_-_93954227 0.17 ENST00000513200.3
ENST00000329378.7
ENST00000312498.7
KIAA0825
chr22_+_39353527 0.17 ENST00000249116.2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3A
chr12_+_10366223 0.17 ENST00000545290.1
GABA(A) receptor-associated protein like 1
chr12_+_10365082 0.17 ENST00000545859.1
GABA(A) receptor-associated protein like 1
chr11_-_47447970 0.17 ENST00000298852.3
ENST00000530912.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr11_-_4599050 0.16 ENST00000307616.1
chromosome 11 open reading frame 40
chr1_+_214163033 0.16 ENST00000607425.1
prospero homeobox 1
chr12_-_10826612 0.16 ENST00000535345.1
ENST00000542562.1
serine/threonine/tyrosine kinase 1
chr6_+_33378517 0.16 ENST00000428274.1
PHD finger protein 1
chr12_-_49523896 0.16 ENST00000549870.1
tubulin, alpha 1b
chr14_-_74462922 0.16 ENST00000553284.1
ectonucleoside triphosphate diphosphohydrolase 5
chr16_+_22308717 0.16 ENST00000299853.5
ENST00000564209.1
ENST00000565358.1
ENST00000418581.2
ENST00000564883.1
ENST00000359210.4
ENST00000563024.1
polymerase (RNA) III (DNA directed) polypeptide E (80kD)
chr1_-_158656488 0.15 ENST00000368147.4
spectrin, alpha, erythrocytic 1 (elliptocytosis 2)
chr4_-_87374330 0.15 ENST00000511328.1
ENST00000503911.1
mitogen-activated protein kinase 10
chr20_-_1306391 0.15 ENST00000339987.3
syndecan binding protein (syntenin) 2
chr14_-_65769392 0.15 ENST00000555736.1
CTD-2509G16.5
chr11_-_2924720 0.15 ENST00000455942.2
solute carrier family 22 (organic cation transporter), member 18 antisense
chr1_+_14075903 0.15 ENST00000343137.4
ENST00000503842.1
ENST00000407521.3
ENST00000505823.1
PR domain containing 2, with ZNF domain
chr17_+_16284399 0.15 ENST00000535788.1
ubiquitin B
chr3_+_183903811 0.14 ENST00000429586.2
ENST00000292808.5
ATP-binding cassette, sub-family F (GCN20), member 3
chr3_-_186262166 0.14 ENST00000307944.5
crystallin, gamma S
chr11_+_123396307 0.14 ENST00000456860.2
GRAM domain containing 1B
chr19_-_54604083 0.14 ENST00000391761.1
ENST00000356532.3
ENST00000359649.4
ENST00000358375.4
ENST00000391760.1
ENST00000351806.4
osteoclast associated, immunoglobulin-like receptor
chr11_+_123325106 0.14 ENST00000525757.1
long intergenic non-protein coding RNA 1059
chr2_-_191885686 0.14 ENST00000432058.1
signal transducer and activator of transcription 1, 91kDa
chr22_-_39637135 0.14 ENST00000440375.1
platelet-derived growth factor beta polypeptide
chr21_+_33031935 0.14 ENST00000270142.6
ENST00000389995.4
superoxide dismutase 1, soluble
chr3_+_184038234 0.14 ENST00000427607.1
ENST00000457456.1
eukaryotic translation initiation factor 4 gamma, 1
chr20_+_42839600 0.13 ENST00000439943.1
ENST00000437730.1
OSER1 antisense RNA 1 (head to head)
chr18_+_61637159 0.13 ENST00000397985.2
ENST00000353706.2
ENST00000542677.1
ENST00000397988.3
ENST00000448851.1
serpin peptidase inhibitor, clade B (ovalbumin), member 8
chr2_+_54342533 0.13 ENST00000406041.1
acylphosphatase 2, muscle type
chr2_-_11606275 0.13 ENST00000381525.3
ENST00000362009.4
E2F transcription factor 6
chr7_+_139529040 0.13 ENST00000455353.1
ENST00000458722.1
ENST00000411653.1
thromboxane A synthase 1 (platelet)
chr6_-_11232891 0.13 ENST00000379433.5
ENST00000379446.5
neural precursor cell expressed, developmentally down-regulated 9
chr17_+_18625336 0.13 ENST00000395671.4
ENST00000571542.1
ENST00000395672.2
ENST00000414850.2
ENST00000424146.2
tripartite motif containing 16-like
chr11_-_128894053 0.13 ENST00000392657.3
Rho GTPase activating protein 32
chr3_+_184038073 0.13 ENST00000428387.1
ENST00000434061.2
eukaryotic translation initiation factor 4 gamma, 1
chr3_+_184037466 0.13 ENST00000441154.1
eukaryotic translation initiation factor 4 gamma, 1
chr15_-_34502197 0.12 ENST00000557877.1
katanin p80 subunit B-like 1
chr19_-_10613421 0.12 ENST00000393623.2
kelch-like ECH-associated protein 1
chr22_+_21987005 0.12 ENST00000607942.1
ENST00000425975.1
ENST00000292779.3
coiled-coil domain containing 116
chr17_+_30771279 0.12 ENST00000261712.3
ENST00000578213.1
ENST00000457654.2
ENST00000579451.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr18_-_55253830 0.12 ENST00000591215.1
ferrochelatase
chrX_-_24665353 0.12 ENST00000379144.2
phosphate cytidylyltransferase 1, choline, beta
chr12_-_57081940 0.12 ENST00000436399.2
prostaglandin E synthase 3 (cytosolic)
chr2_-_220119280 0.12 ENST00000392088.2
tubulin, alpha 4a
chr16_-_1429674 0.12 ENST00000403703.1
ENST00000397464.1
ENST00000402641.2
unkempt family zinc finger-like
chr16_-_30125177 0.12 ENST00000406256.3
glycerophosphodiester phosphodiesterase domain containing 3
chr7_+_141463897 0.12 ENST00000247879.2
taste receptor, type 2, member 3
chr22_+_20008678 0.12 ENST00000434168.1
transport and golgi organization 2 homolog (Drosophila)
chr4_-_44450814 0.12 ENST00000360029.3
potassium channel tetramerization domain containing 8
chr15_-_43212836 0.12 ENST00000566931.1
ENST00000564431.1
ENST00000567274.1
tau tubulin kinase 2
chr22_+_39916558 0.12 ENST00000337304.2
ENST00000396680.1
activating transcription factor 4
chr6_-_35888905 0.12 ENST00000510290.1
ENST00000423325.2
ENST00000373822.1
SRSF protein kinase 1
chr17_-_79604075 0.12 ENST00000374747.5
ENST00000539314.1
ENST00000331134.6
nuclear protein localization 4 homolog (S. cerevisiae)
chr1_+_36554470 0.12 ENST00000373178.4
ADP-ribosylhydrolase like 2
chr19_+_38865398 0.12 ENST00000585598.1
ENST00000602911.1
ENST00000592561.1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr16_-_28222797 0.11 ENST00000569951.1
ENST00000565698.1
exportin 6
chr12_+_6644443 0.11 ENST00000396858.1
glyceraldehyde-3-phosphate dehydrogenase
chr12_-_125399573 0.11 ENST00000339647.5
ubiquitin C
chr12_-_51611477 0.11 ENST00000389243.4
POU class 6 homeobox 1
chr14_+_71165292 0.11 ENST00000553682.1
RP6-65G23.1
chr17_-_8301132 0.11 ENST00000399398.2
ring finger protein 222
chr17_-_42276574 0.11 ENST00000589805.1
ataxin 7-like 3
chr4_+_123747834 0.11 ENST00000264498.3
fibroblast growth factor 2 (basic)
chr21_+_19273574 0.11 ENST00000400128.1
chondrolectin
chr18_-_72920372 0.11 ENST00000581620.1
ENST00000582437.1
zinc binding alcohol dehydrogenase domain containing 2
chr17_+_16284104 0.11 ENST00000577958.1
ENST00000302182.3
ENST00000577640.1
ubiquitin B
chr5_+_179247759 0.11 ENST00000389805.4
ENST00000504627.1
ENST00000402874.3
ENST00000510187.1
sequestosome 1
chr19_-_44324750 0.11 ENST00000594049.1
ENST00000414615.2
LY6/PLAUR domain containing 5
chr20_+_10199468 0.11 ENST00000254976.2
ENST00000304886.2
synaptosomal-associated protein, 25kDa
chr3_+_100053542 0.11 ENST00000394140.4
nitrilase family, member 2
chr17_-_73150629 0.11 ENST00000356033.4
ENST00000405458.3
ENST00000409753.3
hematological and neurological expressed 1
chr20_-_1306351 0.10 ENST00000381812.1
syndecan binding protein (syntenin) 2
chr20_-_1309809 0.10 ENST00000360779.3
syndecan binding protein (syntenin) 2
chr15_-_43212996 0.10 ENST00000567840.1
tau tubulin kinase 2
chr18_+_21594384 0.10 ENST00000584250.1
tetratricopeptide repeat domain 39C
chr20_-_634000 0.10 ENST00000381962.3
sulfiredoxin 1
chr9_+_26746951 0.10 ENST00000523363.1
RP11-18A15.1
chrX_-_24665208 0.10 ENST00000356768.4
phosphate cytidylyltransferase 1, choline, beta
chr11_-_47447767 0.10 ENST00000530651.1
ENST00000524447.2
ENST00000531051.2
ENST00000526993.1
ENST00000602866.1
proteasome (prosome, macropain) 26S subunit, ATPase, 3
chr19_+_38865176 0.10 ENST00000215071.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr2_+_173955327 0.10 ENST00000422149.1
Mitogen-activated protein kinase kinase kinase MLT
chr14_-_95942173 0.09 ENST00000334258.5
ENST00000557275.1
ENST00000553340.1
spectrin repeat containing, nuclear envelope family member 3
chr17_-_7518145 0.09 ENST00000250113.7
ENST00000571597.1
fragile X mental retardation, autosomal homolog 2
chr2_-_233641265 0.09 ENST00000438786.1
ENST00000409779.1
ENST00000233826.3
potassium inwardly-rectifying channel, subfamily J, member 13
chr17_-_28619059 0.09 ENST00000580709.1
bleomycin hydrolase
chr13_+_78109804 0.09 ENST00000535157.1
sciellin
chr19_-_46142680 0.09 ENST00000245925.3
echinoderm microtubule associated protein like 2
chr19_-_46142637 0.09 ENST00000590043.1
ENST00000589876.1
echinoderm microtubule associated protein like 2
chr9_+_116917807 0.09 ENST00000356083.3
collagen, type XXVII, alpha 1
chr17_-_79818354 0.09 ENST00000576541.1
ENST00000576380.1
ENST00000571617.1
ENST00000576052.1
ENST00000576390.1
ENST00000573778.2
ENST00000439918.2
ENST00000574914.1
ENST00000331483.4
prolyl 4-hydroxylase, beta polypeptide
chr20_+_2796948 0.09 ENST00000361033.1
ENST00000380585.1
transmembrane protein 239
chr19_-_14992264 0.09 ENST00000327462.2
olfactory receptor, family 7, subfamily A, member 17
chr9_-_35112376 0.09 ENST00000488109.2
family with sequence similarity 214, member B
chr19_-_51568324 0.09 ENST00000595547.1
ENST00000335422.3
ENST00000595793.1
ENST00000596955.1
kallikrein-related peptidase 13
chr13_+_114567131 0.08 ENST00000608651.1
GAS6 antisense RNA 2 (head to head)
chrX_+_30671476 0.08 ENST00000378946.3
ENST00000378943.3
ENST00000378945.3
ENST00000427190.1
ENST00000378941.3
glycerol kinase
chr9_-_140082983 0.08 ENST00000323927.2
anaphase promoting complex subunit 2
chr3_+_126423045 0.08 ENST00000290913.3
ENST00000508789.1
coiled-coil-helix-coiled-coil-helix domain containing 6
chr2_-_11605966 0.08 ENST00000307236.4
ENST00000542100.1
ENST00000546212.1
E2F transcription factor 6
chr3_+_120315149 0.08 ENST00000184266.2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 4, 15kDa
chr7_-_75988321 0.08 ENST00000307630.3
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma
chrX_+_99899180 0.08 ENST00000373004.3
sushi-repeat containing protein, X-linked 2
chr18_+_55712915 0.08 ENST00000592846.1
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
chr7_+_139529085 0.08 ENST00000539806.1
thromboxane A synthase 1 (platelet)
chr17_-_1395954 0.08 ENST00000359786.5
myosin IC
chr6_-_24799117 0.08 ENST00000565469.1
chromosome 6 open reading frame 229
chr9_-_34458531 0.08 ENST00000379089.1
ENST00000379087.1
ENST00000379084.1
ENST00000379081.1
ENST00000379080.1
ENST00000422409.1
ENST00000379078.1
ENST00000445726.1
ENST00000297620.4
family with sequence similarity 219, member A
chr10_+_122216316 0.08 ENST00000398250.1
ENST00000439221.1
ENST00000398248.1
phosphatidic acid phosphatase type 2 domain containing 1A
chr8_+_39972170 0.08 ENST00000521257.1
RP11-359E19.2
chr22_-_32058416 0.08 ENST00000439502.2
phosphatidylserine decarboxylase
chr1_+_26605618 0.08 ENST00000270792.5
SH3 domain binding glutamic acid-rich protein like 3
chr9_-_26947220 0.08 ENST00000520884.1
phospholipase A2-activating protein
chr4_-_987217 0.08 ENST00000361661.2
ENST00000398516.2
solute carrier family 26 (anion exchanger), member 1
chr5_+_179125368 0.08 ENST00000502296.1
ENST00000504734.1
ENST00000415618.2
calnexin
chr16_+_57844549 0.08 ENST00000564282.1
uncharacterized protein LOC388282
chr17_-_61905005 0.07 ENST00000584574.1
ENST00000585145.1
ENST00000427159.2
FtsJ homolog 3 (E. coli)
chr2_-_10588630 0.07 ENST00000234111.4
ornithine decarboxylase 1
chr20_+_42839722 0.07 ENST00000442383.1
ENST00000435163.1
OSER1 antisense RNA 1 (head to head)
chr10_+_127661942 0.07 ENST00000417114.1
ENST00000445510.1
ENST00000368691.1
fibronectin type III and ankyrin repeat domains 1
chr6_+_53948328 0.07 ENST00000370876.2
muscular LMNA-interacting protein
chr16_+_56642489 0.07 ENST00000561491.1
metallothionein 2A
chr6_-_31745085 0.07 ENST00000375686.3
ENST00000447450.1
von Willebrand factor A domain containing 7

Network of associatons between targets according to the STRING database.

First level regulatory network of BACH1_NFE2_NFE2L2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0002384 hepatic immune response(GO:0002384) response to prolactin(GO:1990637)
0.2 1.5 GO:0051549 positive regulation of keratinocyte migration(GO:0051549)
0.1 0.4 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.8 GO:0045229 cell envelope organization(GO:0043163) external encapsulating structure organization(GO:0045229)
0.1 0.4 GO:1900241 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.1 0.4 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.3 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 1.3 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.1 0.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.2 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.2 GO:0061114 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) negative regulation of bile acid biosynthetic process(GO:0070858) acinar cell differentiation(GO:0090425) negative regulation of bile acid metabolic process(GO:1904252) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.0 0.1 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.0 0.1 GO:0042660 positive regulation of cell fate specification(GO:0042660)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.1 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.1 GO:0006117 acetaldehyde metabolic process(GO:0006117)
0.0 0.7 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.3 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.1 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.4 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.2 GO:0051546 keratinocyte migration(GO:0051546)
0.0 0.4 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.2 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.2 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.1 GO:0070541 response to platinum ion(GO:0070541)
0.0 0.2 GO:0070383 DNA cytosine deamination(GO:0070383)
0.0 0.4 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0035865 cellular response to potassium ion(GO:0035865)
0.0 0.4 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.3 GO:0030321 transepithelial chloride transport(GO:0030321)
0.0 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.4 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.1 GO:0015728 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.0 0.1 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.4 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.0 GO:0060168 regulation of adenosine receptor signaling pathway(GO:0060167) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 1.3 GO:0006521 regulation of cellular amino acid metabolic process(GO:0006521)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.0 0.6 GO:0005980 glycogen catabolic process(GO:0005980)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.0 GO:0050894 determination of affect(GO:0050894)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.0 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.3 GO:0071625 vocalization behavior(GO:0071625)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.2 GO:0034515 proteasome storage granule(GO:0034515)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751) sperm plasma membrane(GO:0097524)
0.1 0.2 GO:0036387 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.0 0.1 GO:0035525 NF-kappaB p50/p65 complex(GO:0035525)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.5 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 2.5 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0097452 GAIT complex(GO:0097452)
0.0 0.9 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0014802 terminal cisterna(GO:0014802)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0019774 proteasome core complex, beta-subunit complex(GO:0019774)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.4 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.1 0.3 GO:0015322 proton-dependent oligopeptide secondary active transmembrane transporter activity(GO:0005427) secondary active oligopeptide transmembrane transporter activity(GO:0015322)
0.1 0.3 GO:0031783 corticotropin hormone receptor binding(GO:0031780) type 5 melanocortin receptor binding(GO:0031783)
0.1 0.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.8 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.2 GO:0004917 interleukin-7 receptor activity(GO:0004917)
0.1 0.2 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.1 GO:0004325 ferrochelatase activity(GO:0004325)
0.0 0.2 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.2 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.0 0.3 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0019828 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) aspartic-type endopeptidase inhibitor activity(GO:0019828) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.7 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.0 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.0 0.1 GO:0008426 protein kinase C inhibitor activity(GO:0008426)
0.0 0.1 GO:0016005 phospholipase A2 activator activity(GO:0016005)
0.0 0.4 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.0 0.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0003947 (N-acetylneuraminyl)-galactosylglucosylceramide N-acetylgalactosaminyltransferase activity(GO:0003947)
0.0 0.4 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.1 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 1.7 GO:0005518 collagen binding(GO:0005518)
0.0 0.1 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.1 GO:0047685 amine sulfotransferase activity(GO:0047685)
0.0 0.1 GO:0070026 nitric oxide binding(GO:0070026)
0.0 0.1 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.0 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.2 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.0 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.0 0.1 GO:0046870 cadmium ion binding(GO:0046870)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.5 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.8 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 1.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.5 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 1.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.3 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.4 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage