GSE58827: Dynamics of the Mouse Liver
Gene Symbol | Gene ID | Gene Info |
---|---|---|
ENSMUSG00000031627.10 | interferon regulatory factor 2 | |
ENSMUSG00000018899.18 | interferon regulatory factor 1 | |
ENSMUSG00000041515.11 | interferon regulatory factor 8 | |
ENSMUSG00000002325.16 | interferon regulatory factor 9 | |
ENSMUSG00000025498.16 | interferon regulatory factor 7 |
Gene | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Irf1 | mm39_v1_chr11_+_53661251_53661346 | 0.65 | 2.0e-05 | Click! |
Irf7 | mm39_v1_chr7_-_140846328_140846394 | 0.55 | 5.1e-04 | Click! |
Irf2 | mm39_v1_chr8_+_47192767_47192829 | 0.36 | 3.1e-02 | Click! |
Irf9 | mm39_v1_chr14_+_55842002_55842036 | 0.29 | 8.1e-02 | Click! |
Irf8 | mm39_v1_chr8_+_121463090_121463124 | -0.19 | 2.7e-01 | Click! |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.5 | 183.6 | GO:0035458 | cellular response to interferon-beta(GO:0035458) |
2.9 | 38.3 | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway(GO:0060340) |
8.7 | 26.0 | GO:1904440 | positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) |
8.1 | 24.4 | GO:0034240 | negative regulation of macrophage fusion(GO:0034240) |
0.2 | 22.9 | GO:0019395 | fatty acid oxidation(GO:0019395) |
2.0 | 21.6 | GO:0035456 | response to interferon-beta(GO:0035456) |
1.3 | 21.3 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
7.0 | 21.1 | GO:0002414 | immune response in mucosal-associated lymphoid tissue(GO:0002386) immunoglobulin transcytosis in epithelial cells(GO:0002414) |
3.5 | 21.0 | GO:1990166 | protein localization to site of double-strand break(GO:1990166) |
4.0 | 19.9 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 90.2 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
0.0 | 83.3 | GO:0005829 | cytosol(GO:0005829) |
0.1 | 74.5 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
5.3 | 73.8 | GO:0020005 | symbiont-containing vacuole membrane(GO:0020005) |
0.0 | 47.5 | GO:0005615 | extracellular space(GO:0005615) |
3.3 | 46.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
3.6 | 28.9 | GO:0042825 | TAP complex(GO:0042825) |
0.5 | 23.0 | GO:0055038 | recycling endosome membrane(GO:0055038) |
0.1 | 16.9 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.3 | 16.7 | GO:0035861 | site of double-strand break(GO:0035861) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 114.2 | GO:0003924 | GTPase activity(GO:0003924) |
2.4 | 40.9 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
0.4 | 30.4 | GO:0019003 | GDP binding(GO:0019003) |
1.1 | 27.5 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
2.1 | 25.6 | GO:0031730 | CCR5 chemokine receptor binding(GO:0031730) |
0.1 | 24.1 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
7.8 | 23.4 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
2.1 | 21.4 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
0.1 | 21.1 | GO:0001047 | core promoter binding(GO:0001047) |
2.1 | 21.0 | GO:0003910 | DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910) |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
2.6 | 29.1 | ST TYPE I INTERFERON PATHWAY | Type I Interferon (alpha/beta IFN) Pathway |
0.2 | 23.4 | PID IL4 2PATHWAY | IL4-mediated signaling events |
0.1 | 22.1 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.7 | 21.8 | ST G ALPHA S PATHWAY | G alpha s Pathway |
0.2 | 18.6 | PID NFAT TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
0.2 | 13.6 | PID CD8 TCR DOWNSTREAM PATHWAY | Downstream signaling in naïve CD8+ T cells |
0.1 | 12.2 | PID SMAD2 3NUCLEAR PATHWAY | Regulation of nuclear SMAD2/3 signaling |
0.0 | 12.2 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
0.1 | 11.5 | SIG PIP3 SIGNALING IN CARDIAC MYOCTES | Genes related to PIP3 signaling in cardiac myocytes |
0.2 | 8.4 | SA CASPASE CASCADE | Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade. |
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 29.9 | REACTOME INTERFERON GAMMA SIGNALING | Genes involved in Interferon gamma signaling |
1.9 | 26.6 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
1.0 | 25.7 | REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI | Genes involved in RIP-mediated NFkB activation via DAI |
1.4 | 24.4 | REACTOME IL 6 SIGNALING | Genes involved in Interleukin-6 signaling |
0.4 | 23.3 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
1.1 | 20.9 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
1.4 | 19.5 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
0.3 | 16.6 | REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 | Genes involved in Autodegradation of the E3 ubiquitin ligase COP1 |
5.2 | 15.7 | REACTOME ENDOSOMAL VACUOLAR PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.5 | 14.7 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |