ISMARA results: Foxj3

Project

GSE58827: Dynamics of the Mouse Liver

Navigation

Downloads

Results for Foxj3_Tbl1xr1

Z-value: 1.85

Motif logo

Transcription factors associated with Foxj3_Tbl1xr1

Gene Symbol	Gene ID	Gene Info
Foxj3 Ensembl NCBI MGI UniProt	ENSMUSG00000032998.17	forkhead box J3
Tbl1xr1 Ensembl NCBI MGI UniProt	ENSMUSG00000027630.14	transducin (beta)-like 1X-linked receptor 1

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Foxj3	mm39_v1_chr4_+_119396849_119396912	0.62	5.5e-05	Click!
Tbl1xr1	mm39_v1_chr3_+_22130866_22130961	0.41	1.3e-02	Click!

Activity profile of Foxj3_Tbl1xr1 motif

Sorted Z-values of Foxj3_Tbl1xr1 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr10_+_79722081 Show fit	20.90	ENSMUST00000046091.7	Elane Ensembl NCBI MGI UniProt Show fit	elastase, neutrophil expressed
chr16_-_36228798 Show fit	16.84	ENSMUST00000023619.8	Stfa2 Ensembl NCBI MGI UniProt Show fit	stefin A2
chr16_+_36004452 Show fit	14.24	ENSMUST00000114858.2	Cstdc4 Ensembl NCBI MGI UniProt Show fit	cystatin domain containing 4
chr7_+_13467422 Show fit	13.63	ENSMUST00000086148.8	Sult2a2 Ensembl NCBI MGI UniProt Show fit	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
chr3_-_90603013 Show fit	13.42	ENSMUST00000069960.12 ENSMUST00000117167.2	S100a9 Ensembl NCBI MGI UniProt Show fit	S100 calcium binding protein A9 (calgranulin B)
chr5_+_90638580 Show fit	12.84	ENSMUST00000042755.7 ENSMUST00000200693.2	Afp Ensembl NCBI MGI UniProt Show fit	alpha fetoprotein
chr7_-_13571334 Show fit	11.75	ENSMUST00000108522.5	Sult2a1 Ensembl NCBI MGI UniProt Show fit	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr1_+_174000304 Show fit	11.05	ENSMUST00000027817.8	Spta1 Ensembl NCBI MGI UniProt Show fit	spectrin alpha, erythrocytic 1
chr10_-_111833138 Show fit	10.24	ENSMUST00000074805.12	Glipr1 Ensembl NCBI MGI UniProt Show fit	GLI pathogenesis-related 1 (glioma)
chr11_-_55075855 Show fit	9.35	ENSMUST00000039305.6	Slc36a2 Ensembl NCBI MGI UniProt Show fit	solute carrier family 36 (proton/amino acid symporter), member 2

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxj3_Tbl1xr1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	35.2	GO:0048821	erythrocyte development(GO:0048821)
0.2	24.7	GO:0051028	mRNA transport(GO:0051028)
8.0	23.9	GO:0070947	neutrophil mediated killing of fungus(GO:0070947)
0.1	23.5	GO:0050853	B cell receptor signaling pathway(GO:0050853)
1.7	23.2	GO:0015816	glycine transport(GO:0015816)
0.7	21.3	GO:0006779	porphyrin-containing compound biosynthetic process(GO:0006779)
0.3	17.7	GO:0051225	spindle assembly(GO:0051225)
1.0	17.3	GO:0001542	ovulation from ovarian follicle(GO:0001542)
4.1	16.4	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.9	16.2	GO:0019370	leukotriene biosynthetic process(GO:0019370)

Showing 1 to 10 of 1,119 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	57.8	GO:0005635	nuclear envelope(GO:0005635)
0.5	36.6	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.2	30.6	GO:0017053	transcriptional repressor complex(GO:0017053)
4.5	22.7	GO:0031838	haptoglobin-hemoglobin complex(GO:0031838)
0.3	22.2	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.2	21.5	GO:0071013	catalytic step 2 spliceosome(GO:0071013)
0.8	19.2	GO:0042581	specific granule(GO:0042581)
0.3	17.7	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1	17.0	GO:0019814	immunoglobulin complex(GO:0019814) immunoglobulin complex, circulating(GO:0042571)
0.3	16.8	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)

Showing 1 to 10 of 411 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	41.4	GO:0003723	RNA binding(GO:0003723)
0.2	27.9	GO:0003735	structural constituent of ribosome(GO:0003735)
2.5	25.4	GO:0050786	RAGE receptor binding(GO:0050786)
6.2	24.6	GO:0031720	haptoglobin binding(GO:0031720)
2.2	24.4	GO:0015187	glycine transmembrane transporter activity(GO:0015187)
0.5	22.5	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.2	20.1	GO:0034987	immunoglobulin receptor binding(GO:0034987)
2.6	18.3	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.1	16.0	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.2	15.7	GO:0030507	spectrin binding(GO:0030507)

Showing 1 to 10 of 654 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	47.8	PID E2F PATHWAY	E2F transcription factor network
0.7	38.5	PID AURORA B PATHWAY	Aurora B signaling
0.2	33.0	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.3	31.9	PID CMYB PATHWAY	C-MYB transcription factor network
0.5	28.4	PID ATR PATHWAY	ATR signaling pathway
0.5	28.2	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.3	18.6	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.5	17.8	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.2	14.6	PID P73PATHWAY	p73 transcription factor network
0.2	14.2	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway

Showing 1 to 10 of 124 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	62.8	REACTOME PEPTIDE CHAIN ELONGATION	Genes involved in Peptide chain elongation
0.5	56.1	REACTOME MITOTIC PROMETAPHASE	Genes involved in Mitotic Prometaphase
1.2	36.2	REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX	Genes involved in Degradation of the extracellular matrix
0.3	30.5	REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL	Genes involved in Cell surface interactions at the vascular wall
0.4	28.8	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.2	23.3	REACTOME INTERFERON SIGNALING	Genes involved in Interferon Signaling
0.3	18.9	REACTOME MRNA SPLICING	Genes involved in mRNA Splicing
0.4	16.1	REACTOME G1 PHASE	Genes involved in G1 Phase
0.6	15.7	REACTOME AMYLOIDS	Genes involved in Amyloids
0.1	15.5	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation

Showing 1 to 10 of 176 entries

Results for Foxj3_Tbl1xr1

Z-value: 1.85

Motif logo

Transcription factors associated with Foxj3_Tbl1xr1

Activity-expression correlation:

Activity profile of Foxj3_Tbl1xr1 motif

Sorted Z-values of Foxj3_Tbl1xr1 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxj3_Tbl1xr1

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: