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avrg: GSE58827: Dynamics of the Mouse Liver
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Results for Prdm14
Z-value: 0.66
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Transcription factors associated with Prdm14
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Prdm14 | mm39_v1_chr1_-_13197387_13197473 | -0.37 | 2.7e-02 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of Prdm14
| Promoter | Score | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr1_+_88062508 Show fit | 2.15 |
ENSMUST00000113134.8
ENSMUST00000140092.8 |
UDP glucuronosyltransferase 1 family, polypeptide A6A |
|
| chr4_+_133280680 Show fit | 2.13 |
ENSMUST00000042706.3
|
nuclear receptor subfamily 0, group B, member 2 |
|
| chr1_+_88030951 Show fit | 1.97 |
ENSMUST00000113135.6
ENSMUST00000113138.8 |
UDP glucuronosyltransferase 1 family, polypeptide A7C UDP glucuronosyltransferase 1 family, polypeptide A6B |
|
| chr6_+_54016543 Show fit | 1.92 |
ENSMUST00000046856.14
|
chimerin 2 |
|
| chr6_+_72332449 Show fit | 1.65 |
ENSMUST00000206064.2
|
transmembrane protein 150A |
|
| chr17_-_35081129 Show fit | 1.40 |
ENSMUST00000154526.8
|
complement factor B |
|
| chr6_+_72332423 Show fit | 1.33 |
ENSMUST00000069695.9
ENSMUST00000132243.3 |
transmembrane protein 150A |
|
| chr17_-_35081456 Show fit | 1.32 |
ENSMUST00000025229.11
ENSMUST00000176203.9 ENSMUST00000128767.8 |
complement factor B |
|
| chr6_+_91661074 Show fit | 1.16 |
ENSMUST00000205480.2
ENSMUST00000206545.2 |
solute carrier family 6 (neurotransmitter transporter, taurine), member 6 |
|
| chr8_+_46945826 Show fit | 1.12 |
ENSMUST00000110371.8
|
acyl-CoA synthetase long-chain family member 1 |
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.0 | GO:0046854 | phosphatidylinositol phosphorylation(GO:0046854) |
| 0.2 | 2.7 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.2 | 2.1 | GO:0052697 | flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697) |
| 0.0 | 2.1 | GO:0032024 | positive regulation of insulin secretion(GO:0032024) |
| 0.7 | 2.0 | GO:0006711 | estrogen catabolic process(GO:0006711) |
| 0.7 | 2.0 | GO:0015734 | beta-alanine transport(GO:0001762) taurine transport(GO:0015734) |
| 0.1 | 1.1 | GO:0044539 | long-chain fatty acid import(GO:0044539) |
| 0.0 | 1.0 | GO:0002024 | diet induced thermogenesis(GO:0002024) |
| 0.1 | 0.9 | GO:0006741 | NADP biosynthetic process(GO:0006741) |
| 0.1 | 0.9 | GO:0098719 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | GO:0005778 | peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903) |
| 0.0 | 1.0 | GO:0034707 | chloride channel complex(GO:0034707) |
| 0.0 | 0.9 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.5 | GO:0071782 | endoplasmic reticulum tubular network(GO:0071782) |
| 0.0 | 0.3 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.0 | 0.3 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.1 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.0 | 2.7 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 2.1 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
| 0.7 | 2.0 | GO:0005368 | beta-alanine transmembrane transporter activity(GO:0001761) taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369) |
| 0.2 | 1.1 | GO:0043758 | acetate-CoA ligase (ADP-forming) activity(GO:0043758) |
| 0.0 | 1.0 | GO:0003951 | NAD+ kinase activity(GO:0003951) |
| 0.1 | 0.9 | GO:0015386 | potassium:proton antiporter activity(GO:0015386) |
| 0.1 | 0.9 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.1 | 0.8 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.0 | 0.5 | GO:0031433 | telethonin binding(GO:0031433) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 2.7 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.1 | 2.1 | PID ERB GENOMIC PATHWAY | Validated nuclear estrogen receptor beta network |
| 0.0 | 1.9 | PID RAC1 REG PATHWAY | Regulation of RAC1 activity |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.7 | REACTOME REGULATION OF COMPLEMENT CASCADE | Genes involved in Regulation of Complement cascade |
| 0.1 | 2.0 | REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS | Genes involved in Na+/Cl- dependent neurotransmitter transporters |
| 0.0 | 2.0 | REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY | Genes involved in Nuclear Receptor transcription pathway |
| 0.0 | 1.1 | REACTOME ALPHA LINOLENIC ACID ALA METABOLISM | Genes involved in alpha-linolenic acid (ALA) metabolism |
| 0.0 | 0.9 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 0.8 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.0 | 0.6 | REACTOME SIGNALING BY HIPPO | Genes involved in Signaling by Hippo |
| 0.1 | 0.5 | REACTOME THE ACTIVATION OF ARYLSULFATASES | Genes involved in The activation of arylsulfatases |