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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Zbtb18

Z-value: 2.32

Motif logo

Transcription factors associated with Zbtb18

Gene Symbol Gene ID Gene Info
ENSMUSG00000063659.6 zinc finger and BTB domain containing 18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb18mm10_v2_chr1_+_177445660_177445821-0.241.5e-01Click!

Activity profile of Zbtb18 motif

Sorted Z-values of Zbtb18 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_111691002 19.74 ENSMUST00000034435.5
chymotrypsinogen B1
chr4_-_141825997 17.63 ENSMUST00000102481.3
chymotrypsin-like elastase family, member 2A
chr8_-_105933832 13.18 ENSMUST00000034368.6
chymotrypsin-like
chr17_-_12675833 10.32 ENSMUST00000024596.8
solute carrier family 22 (organic cation transporter), member 1
chr4_-_115496129 9.92 ENSMUST00000030487.2
cytochrome P450, family 4, subfamily a, polypeptide 14
chr2_-_28563362 9.89 ENSMUST00000028161.5
carboxyl ester lipase
chr1_-_150466165 9.82 ENSMUST00000162367.1
ENSMUST00000161611.1
ENSMUST00000161320.1
ENSMUST00000159035.1
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr6_-_41035501 9.37 ENSMUST00000031931.5
RIKEN cDNA 2210010C04 gene
chr8_-_24576297 8.98 ENSMUST00000033953.7
ENSMUST00000121992.1
indoleamine 2,3-dioxygenase 2
chr14_+_30886521 8.96 ENSMUST00000168782.1
inter alpha-trypsin inhibitor, heavy chain 4
chr17_-_84682932 8.56 ENSMUST00000066175.3
ATP-binding cassette, sub-family G (WHITE), member 5
chr14_+_30886476 8.56 ENSMUST00000006703.6
ENSMUST00000078490.5
ENSMUST00000120269.2
inter alpha-trypsin inhibitor, heavy chain 4
chr6_+_37530204 7.95 ENSMUST00000151256.1
aldo-keto reductase family 1, member D1
chr6_+_78405148 7.78 ENSMUST00000023906.2
regenerating islet-derived 2
chr7_-_14446651 7.78 ENSMUST00000125941.1
RIKEN cDNA 2810007J24 gene
chr7_-_14446570 7.77 ENSMUST00000063509.4
RIKEN cDNA 2810007J24 gene
chr6_+_37530173 7.45 ENSMUST00000040987.7
aldo-keto reductase family 1, member D1
chr7_-_19699008 6.99 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
apolipoprotein E
chr1_+_93006328 6.92 ENSMUST00000059676.4
aquaporin 12
chr14_+_37054818 6.70 ENSMUST00000120052.1
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chr1_-_139781236 6.67 ENSMUST00000027612.8
ENSMUST00000111989.2
ENSMUST00000111986.2
predicted gene 4788
chr7_-_99695628 6.58 ENSMUST00000145381.1
solute carrier organic anion transporter family, member 2b1
chr2_+_43555321 6.53 ENSMUST00000028223.2
kynureninase (L-kynurenine hydrolase)
chr17_-_28560704 6.44 ENSMUST00000114785.1
ENSMUST00000025062.3
colipase, pancreatic
chr7_-_99695572 6.33 ENSMUST00000137914.1
solute carrier organic anion transporter family, member 2b1
chr2_+_43555342 6.17 ENSMUST00000112826.1
ENSMUST00000050511.6
kynureninase (L-kynurenine hydrolase)
chr7_+_44225430 5.90 ENSMUST00000075162.3
kallikrein 1
chr12_-_103457195 5.47 ENSMUST00000044687.6
interferon, alpha-inducible protein 27 like 2B
chr4_-_49506538 5.22 ENSMUST00000043056.2
bile acid-Coenzyme A: amino acid N-acyltransferase
chr17_-_45686120 5.09 ENSMUST00000143907.1
ENSMUST00000127065.1
transmembrane protein 63b
chr7_-_99695809 5.00 ENSMUST00000107086.2
solute carrier organic anion transporter family, member 2b1
chr12_-_103989950 4.95 ENSMUST00000120251.2
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr17_+_10840361 4.88 ENSMUST00000097413.3
Parkinson disease (autosomal recessive, juvenile) 2, parkin
chr9_-_103219823 4.87 ENSMUST00000168142.1
transferrin
chr17_-_45685973 4.84 ENSMUST00000145873.1
transmembrane protein 63b
chr18_+_45268876 4.83 ENSMUST00000183850.1
ENSMUST00000066890.7
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr14_-_31640878 4.79 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
2-hydroxyacyl-CoA lyase 1
chr3_-_131303144 4.48 ENSMUST00000106337.2
cytochrome P450, family 2, subfamily u, polypeptide 1
chr12_-_103989917 4.46 ENSMUST00000151709.2
ENSMUST00000176246.1
ENSMUST00000074693.7
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 11
chr2_+_102706356 4.33 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_-_97417730 4.30 ENSMUST00000043077.7
thyroid hormone responsive
chr16_+_26581704 4.27 ENSMUST00000096129.2
ENSMUST00000166294.2
ENSMUST00000174202.1
ENSMUST00000023156.6
interleukin 1 receptor accessory protein
chr16_+_91269759 4.22 ENSMUST00000056882.5
oligodendrocyte transcription factor 1
chr4_+_141242850 4.17 ENSMUST00000138096.1
ENSMUST00000006618.2
ENSMUST00000125392.1
Rho guanine nucleotide exchange factor (GEF) 19
chr17_-_46487641 4.16 ENSMUST00000047034.8
tau tubulin kinase 1
chr1_-_139858684 4.14 ENSMUST00000094489.3
complement factor H-related 2
chr7_+_122671378 4.08 ENSMUST00000182563.1
calcium channel, voltage-dependent, gamma subunit 3
chr19_+_34290653 4.01 ENSMUST00000025691.5
ENSMUST00000112472.2
Fas (TNF receptor superfamily member 6)
chr11_+_99047311 3.98 ENSMUST00000140772.1
insulin-like growth factor binding protein 4
chr19_+_41029275 3.92 ENSMUST00000051806.4
ENSMUST00000112200.1
deoxynucleotidyltransferase, terminal
chr1_+_160978576 3.86 ENSMUST00000064725.5
serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1
chr1_-_162866502 3.84 ENSMUST00000046049.7
flavin containing monooxygenase 1
chr9_+_44066993 3.73 ENSMUST00000034508.7
ubiquitin specific peptidase 2
chr5_-_92328068 3.73 ENSMUST00000113093.3
chemokine (C-X-C motif) ligand 9
chr3_-_108536466 3.71 ENSMUST00000048012.6
ENSMUST00000106626.2
ENSMUST00000106625.3
RIKEN cDNA 5330417C22 gene
chr1_+_164796723 3.71 ENSMUST00000027861.4
dermatopontin
chr6_-_35326123 3.61 ENSMUST00000051176.7
family with sequence similarity 180, member A
chr11_-_115062177 3.36 ENSMUST00000062787.7
CD300e antigen
chr10_+_63061582 3.32 ENSMUST00000020266.8
ENSMUST00000178684.1
phenazine biosynthesis-like protein domain containing 1
chr2_-_25500613 3.17 ENSMUST00000040042.4
complement component 8, gamma polypeptide
chr9_+_44067072 3.14 ENSMUST00000177054.1
ubiquitin specific peptidase 2
chr17_-_32947389 3.11 ENSMUST00000075253.6
cytochrome P450, family 4, subfamily f, polypeptide 13
chr7_+_122671401 3.11 ENSMUST00000182095.1
calcium channel, voltage-dependent, gamma subunit 3
chr17_-_32947372 3.04 ENSMUST00000139353.1
cytochrome P450, family 4, subfamily f, polypeptide 13
chr17_-_7385305 3.03 ENSMUST00000070059.3
predicted gene 9992
chr12_-_30373358 3.03 ENSMUST00000021004.7
syntrophin, gamma 2
chr4_-_130279205 3.02 ENSMUST00000120126.2
serine incorporator 2
chr11_-_68386974 3.00 ENSMUST00000135141.1
netrin 1
chr13_+_58806564 2.99 ENSMUST00000109838.2
neurotrophic tyrosine kinase, receptor, type 2
chr8_+_4134733 2.99 ENSMUST00000130372.1
CD209g antigen
chr4_-_116017854 2.97 ENSMUST00000049095.5
fatty acid amide hydrolase
chr7_-_114415128 2.91 ENSMUST00000163996.1
RIKEN cDNA 4933406I18 gene
chr9_+_119357381 2.91 ENSMUST00000039610.8
xylulokinase homolog (H. influenzae)
chr14_-_63509092 2.88 ENSMUST00000022522.8
L-threonine dehydrogenase
chr4_-_130275542 2.86 ENSMUST00000154846.1
ENSMUST00000105996.1
serine incorporator 2
chr1_+_45311538 2.83 ENSMUST00000087883.6
collagen, type III, alpha 1
chr8_+_13435459 2.82 ENSMUST00000167071.1
ENSMUST00000167505.1
transmembrane protein 255B
chr11_+_118428493 2.80 ENSMUST00000017590.2
C1q and tumor necrosis factor related protein 1
chr14_-_122913085 2.78 ENSMUST00000162164.1
ENSMUST00000110679.2
ENSMUST00000038075.5
gamma-glutamylamine cyclotransferase
chr4_-_108032069 2.76 ENSMUST00000106709.2
podocan
chr4_-_108031938 2.72 ENSMUST00000106708.1
podocan
chr17_-_45686214 2.70 ENSMUST00000113523.2
transmembrane protein 63b
chr11_+_87582201 2.69 ENSMUST00000133202.1
septin 4
chr14_+_41105359 2.67 ENSMUST00000047286.6
methionine adenosyltransferase I, alpha
chr1_+_88070765 2.64 ENSMUST00000073772.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr5_+_135725713 2.62 ENSMUST00000127096.1
P450 (cytochrome) oxidoreductase
chr17_-_13131791 2.59 ENSMUST00000084966.5
unc-93 homolog A (C. elegans)
chr4_-_130275523 2.56 ENSMUST00000146478.1
serine incorporator 2
chr19_-_42202150 2.51 ENSMUST00000018966.7
secreted frizzled-related sequence protein 5
chr12_-_104013640 2.50 ENSMUST00000058464.4
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
chrX_-_8018492 2.48 ENSMUST00000033503.2
glyoxalase domain containing 5
chr6_-_23132981 2.47 ENSMUST00000031707.7
aminoadipate-semialdehyde synthase
chr7_+_43950614 2.45 ENSMUST00000072204.4
kallikrein 1-related peptidase b8
chr5_-_108448882 2.36 ENSMUST00000031455.3
major facilitator superfamily domain containing 7A
chr18_-_32139570 2.36 ENSMUST00000171765.1
protein C
chr1_-_132139605 2.33 ENSMUST00000112362.2
cyclin-dependent kinase 18
chr1_+_88138364 2.31 ENSMUST00000014263.4
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr2_-_150904620 2.24 ENSMUST00000056149.8
abhydrolase domain containing 12
chr7_-_79848191 2.23 ENSMUST00000107392.1
alanyl (membrane) aminopeptidase
chr8_-_4105764 2.22 ENSMUST00000138439.1
ENSMUST00000145007.1
CD209f antigen
chr5_+_135674572 2.21 ENSMUST00000153515.1
P450 (cytochrome) oxidoreductase
chr2_-_27247260 2.19 ENSMUST00000102886.3
ENSMUST00000129975.1
sarcosine dehydrogenase
chr12_+_14494561 2.19 ENSMUST00000052528.3
predicted pseudogene 9847
chr14_-_68582078 2.18 ENSMUST00000022641.7
ADAM-like, decysin 1
chr3_+_146597077 2.14 ENSMUST00000029837.7
ENSMUST00000121133.1
urate oxidase
chr18_-_12862341 2.13 ENSMUST00000121888.1
oxysterol binding protein-like 1A
chr4_+_20007938 2.12 ENSMUST00000125799.1
ENSMUST00000121491.1
tocopherol (alpha) transfer protein
chr5_-_38491948 2.11 ENSMUST00000129099.1
solute carrier family 2 (facilitated glucose transporter), member 9
chr17_-_12868126 2.11 ENSMUST00000089015.3
MAS1 oncogene
chr11_-_74925925 2.10 ENSMUST00000121738.1
serine racemase
chr14_+_31641051 2.09 ENSMUST00000090147.6
biotinidase
chrX_-_162643575 2.06 ENSMUST00000101102.1
RALBP1 associated Eps domain containing protein 2
chr9_-_36797303 2.06 ENSMUST00000115086.5
etoposide induced 2.4 mRNA
chr7_+_145300806 2.04 ENSMUST00000033386.5
MAS-related GPR, member F
chr13_+_30336433 2.00 ENSMUST00000066412.7
angiotensin II receptor, type 1a
chr6_+_91156665 2.00 ENSMUST00000041736.4
histone deacetylase 11
chr6_-_129237948 1.98 ENSMUST00000181238.1
ENSMUST00000180379.1
RIKEN cDNA 2310001H17 gene
chr1_-_132139666 1.98 ENSMUST00000027697.5
cyclin-dependent kinase 18
chr6_+_91156772 1.98 ENSMUST00000143621.1
histone deacetylase 11
chr11_+_118428203 1.98 ENSMUST00000124861.1
C1q and tumor necrosis factor related protein 1
chr7_+_126950518 1.95 ENSMUST00000106335.1
ENSMUST00000146017.1
seizure related 6 homolog like 2
chr2_-_65239092 1.90 ENSMUST00000156643.1
Cobl-like 1
chr19_+_43838803 1.90 ENSMUST00000099413.2
predicted gene 10768
chr7_+_126950687 1.88 ENSMUST00000106333.1
seizure related 6 homolog like 2
chr12_+_85288591 1.86 ENSMUST00000059341.4
zinc finger, C2HC-type containing 1C
chr7_+_145300889 1.86 ENSMUST00000117718.1
MAS-related GPR, member F
chr15_+_31568791 1.82 ENSMUST00000162532.1
carboxymethylenebutenolidase-like (Pseudomonas)
chr14_+_41151442 1.81 ENSMUST00000047095.2
mannose-binding lectin (protein A) 1
chr12_+_29938036 1.81 ENSMUST00000122328.1
ENSMUST00000118321.1
peroxidasin homolog (Drosophila)
chrX_-_162643629 1.81 ENSMUST00000112334.1
RALBP1 associated Eps domain containing protein 2
chr6_+_70726430 1.80 ENSMUST00000103410.1
immunoglobulin kappa constant
chr4_+_60003438 1.80 ENSMUST00000107517.1
ENSMUST00000107520.1
major urinary protein 6
chr11_+_101330605 1.79 ENSMUST00000103105.3
amine oxidase, copper containing 3
chr11_-_110095974 1.77 ENSMUST00000100287.2
ATP-binding cassette, sub-family A (ABC1), member 8a
chr18_+_20665250 1.74 ENSMUST00000075312.3
transthyretin
chr11_-_109722214 1.74 ENSMUST00000020938.7
family with sequence similarity 20, member A
chr16_+_56204313 1.73 ENSMUST00000160116.1
ENSMUST00000069936.7
interphotoreceptor matrix proteoglycan 2
chr12_-_113361232 1.70 ENSMUST00000103423.1
Immunoglobulin heavy constant gamma 3
chr6_+_91157373 1.69 ENSMUST00000155007.1
histone deacetylase 11
chr19_-_41385070 1.69 ENSMUST00000059672.7
phosphoinositide-3-kinase adaptor protein 1
chr11_+_80154103 1.67 ENSMUST00000021050.7
ArfGAP with dual PH domains 2
chr9_-_58555129 1.67 ENSMUST00000165365.1
CD276 antigen
chr6_-_50043657 1.67 ENSMUST00000177892.1
predicted gene, 21786
chr2_-_168734236 1.67 ENSMUST00000109175.2
ATPase, class II, type 9A
chr3_+_81932601 1.67 ENSMUST00000029649.2
cathepsin O
chr17_+_79626669 1.67 ENSMUST00000086570.1
RIKEN cDNA 4921513D11 gene
chr15_+_31568851 1.66 ENSMUST00000070918.6
carboxymethylenebutenolidase-like (Pseudomonas)
chr6_+_72355425 1.65 ENSMUST00000069695.2
ENSMUST00000132243.1
transmembrane protein 150A
chr17_+_45686322 1.65 ENSMUST00000024734.7
mitochondrial ribosomal protein L14
chr19_-_5394385 1.65 ENSMUST00000044527.4
testis specific 10 interacting protein
chr5_+_135353295 1.64 ENSMUST00000111180.2
ENSMUST00000065785.3
tripartite motif-containing 50
chr3_-_88458876 1.63 ENSMUST00000147200.1
ENSMUST00000169222.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr4_-_44066960 1.63 ENSMUST00000173234.1
ENSMUST00000173274.1
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr17_-_57087729 1.62 ENSMUST00000071135.5
tubulin, beta 4A class IVA
chr16_-_45693658 1.61 ENSMUST00000114562.2
ENSMUST00000036617.7
transmembrane serine protease 7
chr14_-_20181773 1.60 ENSMUST00000024011.8
potassium channel, subfamily K, member 5
chr17_-_23684019 1.60 ENSMUST00000085989.5
claudin 9
chr7_+_100009914 1.60 ENSMUST00000107084.1
chordin-like 2
chr7_-_126898249 1.59 ENSMUST00000121532.1
ENSMUST00000032926.5
transmembrane protein 219
chr7_-_98361275 1.58 ENSMUST00000094161.4
ENSMUST00000164726.1
ENSMUST00000167405.1
tsukushi
chr11_+_101331069 1.58 ENSMUST00000017316.6
amine oxidase, copper containing 3
chr11_-_68957445 1.57 ENSMUST00000108671.1
Rho guanine nucleotide exchange factor (GEF) 15
chr11_-_53773187 1.56 ENSMUST00000170390.1
predicted gene, 17334
chr7_+_144175513 1.54 ENSMUST00000105900.1
SH3/ankyrin domain gene 2
chr4_+_152008803 1.53 ENSMUST00000097773.3
kelch-like 21
chr15_-_97020322 1.52 ENSMUST00000166223.1
solute carrier family 38, member 4
chr2_+_144594054 1.52 ENSMUST00000136628.1
predicted gene 561
chr3_-_151749877 1.52 ENSMUST00000029671.7
interferon-induced protein 44
chr6_+_87428986 1.51 ENSMUST00000032125.5
bone morphogenetic protein 10
chr11_-_119086221 1.51 ENSMUST00000026665.7
chromobox 4
chr10_+_79970715 1.50 ENSMUST00000045085.1
glutamate receptor, ionotropic, NMDA3B
chr17_-_10840285 1.49 ENSMUST00000041463.6
PARK2 co-regulated
chr6_+_72598475 1.49 ENSMUST00000070597.6
ENSMUST00000176364.1
ENSMUST00000176168.1
retinol saturase (all trans retinol 13,14 reductase)
chr5_-_24447587 1.48 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
transmembrane and ubiquitin-like domain containing 1
chr11_-_110095937 1.48 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
ATP-binding cassette, sub-family A (ABC1), member 8a
chr7_-_98361310 1.47 ENSMUST00000165257.1
tsukushi
chr2_-_132111440 1.47 ENSMUST00000128899.1
solute carrier family 23 (nucleobase transporters), member 2
chr8_-_36732897 1.46 ENSMUST00000098826.3
deleted in liver cancer 1
chr15_+_44196135 1.46 ENSMUST00000038856.6
ENSMUST00000110289.3
thyrotropin releasing hormone receptor
chr2_+_69135799 1.45 ENSMUST00000041865.7
nitric oxide synthase trafficker
chr15_+_85017138 1.44 ENSMUST00000023070.5
uroplakin 3A
chr10_-_18227473 1.44 ENSMUST00000174592.1
coiled-coil domain containing 28A
chr7_+_44012672 1.43 ENSMUST00000048945.4
kallikrein 1-related petidase b26
chr5_-_120472763 1.43 ENSMUST00000052258.7
ENSMUST00000031594.6
serine dehydratase-like
chr11_-_119355484 1.43 ENSMUST00000100172.2
ENSMUST00000005173.4
N-sulfoglucosamine sulfohydrolase (sulfamidase)
chr11_+_118443471 1.43 ENSMUST00000133558.1
C1q and tumor necrosis factor related protein 1
chr10_-_89621253 1.42 ENSMUST00000020102.7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
chr4_-_44073016 1.41 ENSMUST00000128439.1
ENSMUST00000140724.2
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr17_+_35439155 1.39 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
histocompatibility 2, Q region locus 7
chr16_+_23107754 1.39 ENSMUST00000077605.5
ENSMUST00000115341.3
eukaryotic translation initiation factor 4A2
chr6_+_147531392 1.38 ENSMUST00000111614.2
coiled-coil domain containing 91
chr11_+_49609263 1.38 ENSMUST00000020617.2
FMS-like tyrosine kinase 4
chr9_-_63399216 1.37 ENSMUST00000168665.1
RIKEN cDNA 2300009A05 gene
chr13_+_56438343 1.34 ENSMUST00000021971.5
solute carrier family 25, member 48
chr11_+_44400060 1.32 ENSMUST00000102796.3
ENSMUST00000170513.1
interleukin 12b
chr6_+_17463749 1.32 ENSMUST00000115443.1
met proto-oncogene
chr7_-_68353182 1.30 ENSMUST00000123509.1
ENSMUST00000129965.1
predicted gene 16158
chr11_+_119355551 1.28 ENSMUST00000050880.7
solute carrier family 26, member 11
chr11_-_59182810 1.27 ENSMUST00000108793.2
gap junction protein, gamma 2
chr19_+_47865543 1.27 ENSMUST00000120645.1
glutathione S-transferase omega 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb18

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.4 GO:0030573 bile acid catabolic process(GO:0030573)
4.5 17.9 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
4.2 12.7 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
2.9 8.6 GO:1904730 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
2.8 8.3 GO:1902283 negative regulation of primary amine oxidase activity(GO:1902283)
2.6 10.3 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
2.3 7.0 GO:1903000 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
1.2 9.9 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
1.2 9.8 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
1.2 4.8 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
1.2 8.4 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
1.1 9.0 GO:0006569 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
1.1 3.3 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
1.0 2.9 GO:0042732 D-xylose metabolic process(GO:0042732)
0.8 2.5 GO:2000041 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.8 2.5 GO:0006553 lysine metabolic process(GO:0006553)
0.8 18.9 GO:0061436 establishment of skin barrier(GO:0061436)
0.8 4.8 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.7 2.2 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.7 2.2 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.7 2.9 GO:0006566 threonine metabolic process(GO:0006566)
0.7 4.8 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.7 6.2 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.7 5.4 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.7 4.0 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.7 2.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.6 4.3 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.6 3.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.6 4.8 GO:0072602 interleukin-4 secretion(GO:0072602)
0.6 2.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.6 1.7 GO:0045077 negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.6 3.9 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.5 2.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.5 1.6 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.5 1.5 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.5 1.4 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.5 1.4 GO:0060825 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.5 0.9 GO:0000255 allantoin metabolic process(GO:0000255)
0.4 1.3 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.4 5.2 GO:0019530 glycine metabolic process(GO:0006544) taurine metabolic process(GO:0019530)
0.4 2.1 GO:0042360 vitamin E metabolic process(GO:0042360)
0.4 5.0 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.4 2.0 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.4 15.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.4 2.7 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.4 3.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 3.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.3 2.7 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.3 2.3 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.3 1.0 GO:0010534 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.3 6.9 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.3 1.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.3 2.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.3 3.8 GO:0070995 NADPH oxidation(GO:0070995)
0.3 0.3 GO:0099542 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542)
0.3 4.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.3 0.9 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.3 1.4 GO:0060157 urinary bladder development(GO:0060157)
0.3 1.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.3 1.1 GO:0072014 proximal tubule development(GO:0072014)
0.3 1.4 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.3 1.1 GO:0002780 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.3 0.5 GO:0009957 epidermal cell fate specification(GO:0009957)
0.3 2.1 GO:0071494 cellular response to UV-C(GO:0071494)
0.3 0.8 GO:2000848 positive regulation of corticosteroid hormone secretion(GO:2000848)
0.3 1.3 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.3 4.3 GO:0046415 urate metabolic process(GO:0046415)
0.2 1.0 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 1.0 GO:0061113 pancreas morphogenesis(GO:0061113)
0.2 0.5 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.2 1.0 GO:0034769 basement membrane disassembly(GO:0034769)
0.2 5.4 GO:0001967 suckling behavior(GO:0001967)
0.2 1.7 GO:0070327 thyroid hormone transport(GO:0070327)
0.2 0.9 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 1.5 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.2 0.8 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.2 0.8 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.2 5.7 GO:0006691 leukotriene metabolic process(GO:0006691)
0.2 0.6 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.2 1.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 6.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 3.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.2 1.4 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.2 0.8 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.2 1.7 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.2 1.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.2 4.7 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.2 0.2 GO:1900114 positive regulation of histone H3-K9 trimethylation(GO:1900114)
0.2 3.1 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.2 4.4 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.2 0.7 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2 0.6 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.2 20.6 GO:0007586 digestion(GO:0007586)
0.2 1.1 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2 0.5 GO:0002513 tolerance induction to self antigen(GO:0002513) endocardial cushion fusion(GO:0003274) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.2 0.6 GO:0019364 pyridine nucleotide catabolic process(GO:0019364)
0.2 2.1 GO:0070528 protein kinase C signaling(GO:0070528)
0.1 1.5 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.1 3.3 GO:0071625 vocalization behavior(GO:0071625)
0.1 1.7 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.1 1.8 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 1.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.8 GO:0000042 protein targeting to Golgi(GO:0000042) establishment of protein localization to Golgi(GO:0072600)
0.1 2.2 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.1 2.8 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 1.5 GO:0097264 self proteolysis(GO:0097264)
0.1 0.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 1.7 GO:0070166 enamel mineralization(GO:0070166)
0.1 5.6 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.5 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.9 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.1 2.5 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.1 2.9 GO:0045063 T-helper 1 cell differentiation(GO:0045063)
0.1 0.8 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.1 1.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.5 GO:0033762 response to glucagon(GO:0033762)
0.1 1.0 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 1.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.8 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.3 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 1.8 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 1.1 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 1.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 1.8 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 1.6 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.4 GO:0099624 atrial cardiac muscle cell membrane repolarization(GO:0099624)
0.1 1.4 GO:0046548 retinal rod cell development(GO:0046548)
0.1 1.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.1 3.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.2 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 6.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.1 0.3 GO:0009405 pathogenesis(GO:0009405)
0.1 0.6 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 1.9 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.6 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.1 3.7 GO:0030199 collagen fibril organization(GO:0030199)
0.1 1.3 GO:0008272 sulfate transport(GO:0008272)
0.1 1.3 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.0 GO:0070986 left/right axis specification(GO:0070986)
0.1 1.5 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.1 1.4 GO:0015813 L-glutamate transport(GO:0015813)
0.1 0.2 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 0.5 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.1 1.0 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1 0.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.1 3.9 GO:0048709 oligodendrocyte differentiation(GO:0048709)
0.1 0.6 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.1 0.6 GO:0098762 meiotic prophase I(GO:0007128) prophase(GO:0051324) meiotic cell cycle phase(GO:0098762) meiosis I cell cycle phase(GO:0098764)
0.0 0.8 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.2 GO:0080144 amino acid homeostasis(GO:0080144)
0.0 1.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.2 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.5 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.5 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.7 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.5 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 1.5 GO:0034629 cellular protein complex localization(GO:0034629)
0.0 0.6 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 1.3 GO:0010107 potassium ion import(GO:0010107)
0.0 1.3 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.1 GO:1990859 cellular response to endothelin(GO:1990859)
0.0 0.9 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 0.8 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.1 GO:1903660 transforming growth factor beta activation(GO:0036363) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 3.7 GO:0009062 fatty acid catabolic process(GO:0009062)
0.0 0.9 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.3 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.6 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.6 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.2 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 1.0 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 1.6 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.0 0.9 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.7 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.6 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.0 0.1 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.0 1.0 GO:0032008 activation of MAPKK activity(GO:0000186) positive regulation of TOR signaling(GO:0032008)
0.0 1.2 GO:0016239 positive regulation of macroautophagy(GO:0016239)
0.0 0.4 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.6 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.2 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 1.1 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.6 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0060460 left lung morphogenesis(GO:0060460)
0.0 2.9 GO:0006304 DNA modification(GO:0006304)
0.0 6.0 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 1.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.6 GO:0035987 endodermal cell differentiation(GO:0035987)
0.0 0.2 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.0 0.7 GO:0051452 intracellular pH reduction(GO:0051452)
0.0 1.4 GO:0007566 embryo implantation(GO:0007566)
0.0 1.5 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)
0.0 0.2 GO:0090234 regulation of centromere complex assembly(GO:0090230) regulation of kinetochore assembly(GO:0090234)
0.0 0.1 GO:1901725 regulation of histone deacetylase activity(GO:1901725) positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.9 GO:0016925 protein sumoylation(GO:0016925)
0.0 2.9 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:0010801 negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0 1.0 GO:0007266 Rho protein signal transduction(GO:0007266)
0.0 0.5 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 1.5 GO:0034620 cellular response to unfolded protein(GO:0034620)
0.0 1.8 GO:0048017 inositol lipid-mediated signaling(GO:0048017)
0.0 0.6 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 2.8 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.8 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.0 0.2 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.9 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.0 0.6 GO:0001541 ovarian follicle development(GO:0001541)
0.0 0.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.7 GO:0060711 labyrinthine layer development(GO:0060711)
0.0 1.0 GO:0022900 electron transport chain(GO:0022900)
0.0 0.5 GO:0070613 regulation of protein processing(GO:0070613)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.8 GO:0007416 synapse assembly(GO:0007416)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.9 8.6 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
1.4 7.0 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.0 4.9 GO:0071797 LUBAC complex(GO:0071797) Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.7 4.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.5 4.9 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.4 1.7 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.4 4.2 GO:0031983 vesicle lumen(GO:0031983)
0.4 1.1 GO:0098842 postsynaptic early endosome(GO:0098842)
0.4 1.4 GO:0097450 astrocyte end-foot(GO:0097450)
0.3 10.1 GO:0042588 zymogen granule(GO:0042588)
0.3 1.4 GO:0035841 new growing cell tip(GO:0035841)
0.3 3.2 GO:0005579 membrane attack complex(GO:0005579)
0.3 2.7 GO:0097227 sperm annulus(GO:0097227)
0.3 1.0 GO:0097598 sperm cytoplasmic droplet(GO:0097598)
0.2 21.2 GO:0009925 basal plasma membrane(GO:0009925)
0.2 0.7 GO:0016507 mitochondrial fatty acid beta-oxidation multienzyme complex(GO:0016507) fatty acid beta-oxidation multienzyme complex(GO:0036125)
0.2 1.5 GO:0005827 polar microtubule(GO:0005827)
0.2 2.8 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 0.6 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.2 0.6 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.2 1.8 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 1.6 GO:0033269 internode region of axon(GO:0033269)
0.2 0.5 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.2 1.0 GO:0071986 Ragulator complex(GO:0071986)
0.2 8.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 1.5 GO:0005883 neurofilament(GO:0005883)
0.1 1.0 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.5 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 4.3 GO:0030673 axolemma(GO:0030673)
0.1 4.8 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.1 0.7 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 0.5 GO:1990246 uniplex complex(GO:1990246)
0.1 0.5 GO:1990923 PET complex(GO:1990923)
0.1 0.8 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 2.1 GO:0005922 connexon complex(GO:0005922)
0.1 0.3 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.1 1.5 GO:0035102 PRC1 complex(GO:0035102)
0.1 7.4 GO:0005581 collagen trimer(GO:0005581)
0.1 1.5 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.4 GO:0097381 photoreceptor disc membrane(GO:0097381)
0.1 1.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.6 GO:0031362 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.1 0.5 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.1 0.2 GO:0000814 ESCRT II complex(GO:0000814)
0.1 2.5 GO:0016235 aggresome(GO:0016235)
0.1 2.7 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.6 GO:0045179 apical cortex(GO:0045179)
0.1 2.3 GO:0005604 basement membrane(GO:0005604)
0.1 1.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 91.8 GO:0005615 extracellular space(GO:0005615)
0.1 0.7 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.1 0.5 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 22.5 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 2.9 GO:0005901 caveola(GO:0005901)
0.0 8.3 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 5.3 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 4.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.6 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.8 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 4.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.9 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 1.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 3.0 GO:0005802 trans-Golgi network(GO:0005802)
0.0 25.9 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0060473 cortical granule(GO:0060473)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.8 GO:0000791 euchromatin(GO:0000791)
0.0 0.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.1 15.4 GO:0047787 delta4-3-oxosteroid 5beta-reductase activity(GO:0047787)
3.4 10.3 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
3.3 9.9 GO:0004771 sterol esterase activity(GO:0004771)
3.2 12.7 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
3.0 9.0 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
2.3 7.0 GO:0046911 metal chelating activity(GO:0046911)
1.7 9.9 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
1.3 4.0 GO:0043120 tumor necrosis factor binding(GO:0043120)
1.2 4.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.2 4.8 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
1.1 3.4 GO:0052595 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
1.1 4.3 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.9 17.9 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.7 3.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.7 2.2 GO:0008480 sarcosine dehydrogenase activity(GO:0008480)
0.7 4.3 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.7 17.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.7 2.1 GO:0008431 vitamin E binding(GO:0008431)
0.7 3.5 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.7 4.9 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.6 3.0 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.6 8.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.6 4.1 GO:0001595 angiotensin receptor activity(GO:0001595)
0.6 2.8 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.5 4.8 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.5 3.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.5 1.5 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.5 2.4 GO:0070012 oligopeptidase activity(GO:0070012)
0.4 4.0 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.4 1.3 GO:0030613 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.4 2.0 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.4 11.4 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.4 3.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.4 1.1 GO:0030977 taurine binding(GO:0030977)
0.3 5.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.3 1.4 GO:0019809 spermidine binding(GO:0019809)
0.3 1.7 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.3 1.0 GO:0070540 stearic acid binding(GO:0070540)
0.3 1.0 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.3 1.3 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.3 8.6 GO:0017127 cholesterol transporter activity(GO:0017127)
0.3 60.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 5.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.3 2.1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.3 10.4 GO:0008236 serine-type peptidase activity(GO:0008236)
0.2 3.2 GO:0019841 retinol binding(GO:0019841)
0.2 3.0 GO:0097109 neuroligin family protein binding(GO:0097109)
0.2 1.8 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.2 2.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 4.9 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.2 1.3 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.2 0.8 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.2 2.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.2 1.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 1.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 1.7 GO:0070324 thyroid hormone binding(GO:0070324)
0.2 0.8 GO:0004568 chitinase activity(GO:0004568)
0.2 5.1 GO:0070330 aromatase activity(GO:0070330)
0.2 4.1 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.2 0.5 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.2 0.7 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508) long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2 1.5 GO:0031433 telethonin binding(GO:0031433)
0.2 6.8 GO:0030332 cyclin binding(GO:0030332)
0.1 11.8 GO:0005518 collagen binding(GO:0005518)
0.1 0.9 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 2.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 5.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 2.5 GO:0017166 vinculin binding(GO:0017166)
0.1 1.0 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.1 0.9 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.9 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 0.5 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 0.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.5 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.6 GO:0043237 patched binding(GO:0005113) laminin-1 binding(GO:0043237)
0.1 2.6 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 2.5 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 14.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 0.6 GO:0042731 PH domain binding(GO:0042731)
0.1 0.6 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.1 2.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.1 1.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.7 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 1.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 1.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.9 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.9 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 1.7 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.6 GO:0001618 virus receptor activity(GO:0001618)
0.1 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.5 GO:0016594 glycine binding(GO:0016594)
0.1 1.5 GO:0005537 mannose binding(GO:0005537)
0.1 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.6 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.1 0.8 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.4 GO:0032029 myosin tail binding(GO:0032029)
0.1 1.1 GO:0015250 water channel activity(GO:0015250)
0.1 2.9 GO:0019200 carbohydrate kinase activity(GO:0019200)
0.1 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 0.2 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 2.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 0.8 GO:0008430 selenium binding(GO:0008430)
0.1 1.0 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 1.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 2.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.1 0.6 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.7 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 1.7 GO:0032183 SUMO binding(GO:0032183)
0.1 0.1 GO:0032564 CTP binding(GO:0002135) sulfonylurea receptor binding(GO:0017098) dATP binding(GO:0032564)
0.1 0.5 GO:0034046 poly(G) binding(GO:0034046)
0.1 1.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 0.6 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 1.7 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 2.0 GO:0043531 ADP binding(GO:0043531)
0.0 0.7 GO:0031386 protein tag(GO:0031386)
0.0 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.2 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 2.1 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.5 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.9 GO:0031005 filamin binding(GO:0031005)
0.0 5.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 1.3 GO:0008009 chemokine activity(GO:0008009)
0.0 0.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 1.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 1.0 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.8 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 3.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.1 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.7 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.6 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.3 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.5 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 1.7 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 2.0 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 1.7 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.2 GO:0019003 GDP binding(GO:0019003)
0.0 0.6 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.1 GO:0038100 nodal binding(GO:0038100)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.1 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.6 GO:0030552 cAMP binding(GO:0030552)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 0.7 GO:0000049 tRNA binding(GO:0000049)
0.0 0.6 GO:0036002 pre-mRNA binding(GO:0036002)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 17.0 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.3 3.8 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.2 48.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 3.9 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 4.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 2.0 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 2.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.1 4.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 2.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 3.1 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 3.8 PID IL1 PATHWAY IL1-mediated signaling events
0.1 4.2 PID IL23 PATHWAY IL23-mediated signaling events
0.1 1.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 0.8 PID IFNG PATHWAY IFN-gamma pathway
0.1 3.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.1 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.1 4.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.1 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.1 0.8 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 0.6 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 2.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 9.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 3.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.5 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 1.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 1.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 7.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.5 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.2 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.6 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 17.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
1.2 21.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
1.2 15.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.9 5.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.8 10.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.7 20.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.4 6.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.4 8.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.3 4.0 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.3 3.0 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 5.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 4.0 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.2 2.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.2 1.8 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.2 7.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.2 6.7 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.2 4.4 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 2.1 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.0 REACTOME OPSINS Genes involved in Opsins
0.1 2.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.1 1.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 3.9 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 2.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.1 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 3.0 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 3.3 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.6 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.1 2.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 4.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 3.8 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 4.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 1.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 1.0 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 3.9 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.2 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 2.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 1.1 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 1.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 3.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 1.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes invo