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avrg: GSE58827: Dynamics of the Mouse Liver
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Results for UUGGCAA
Z-value: 2.02
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miRNA associated with seed UUGGCAA
| Name | miRBASE accession |
|---|---|
|
mmu-miR-182-5p
|
MIMAT0000211 |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_+_102658640 Show fit | 12.83 |
ENSMUST00000080210.3
|
solute carrier family 1 (glial high affinity glutamate transporter), member 2 |
|
| chr14_+_37054818 Show fit | 8.77 |
ENSMUST00000120052.1
|
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1 |
|
| chr1_-_121328024 Show fit | 5.69 |
ENSMUST00000003818.7
|
insulin induced gene 2 |
|
| chr9_-_48605147 Show fit | 5.60 |
ENSMUST00000034808.5
ENSMUST00000119426.1 |
nicotinamide N-methyltransferase |
|
| chr6_-_72235559 Show fit | 5.56 |
ENSMUST00000042646.7
|
atonal homolog 8 (Drosophila) |
|
| chr12_-_98577940 Show fit | 4.87 |
ENSMUST00000110113.1
|
potassium channel, subfamily K, member 10 |
|
| chr15_-_86033777 Show fit | 4.86 |
ENSMUST00000016172.7
|
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila) |
|
| chr7_-_81454751 Show fit | 4.83 |
ENSMUST00000098331.3
ENSMUST00000178892.1 |
cytoplasmic polyadenylation element binding protein 1 |
|
| chr12_+_78226627 Show fit | 4.66 |
ENSMUST00000110388.2
ENSMUST00000052472.4 |
gephyrin |
|
| chr7_+_87246649 Show fit | 4.60 |
ENSMUST00000068829.5
ENSMUST00000032781.7 |
NADPH oxidase 4 |
Network of associatons between targets according to the STRING database.
First level regulatory network of UUGGCAA
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 12.1 | GO:0070777 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.4 | 7.4 | GO:0051770 | positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770) |
| 0.4 | 7.2 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
| 0.3 | 5.6 | GO:0045603 | positive regulation of endothelial cell differentiation(GO:0045603) |
| 0.1 | 5.4 | GO:0060395 | SMAD protein signal transduction(GO:0060395) |
| 0.3 | 4.9 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 1.6 | 4.7 | GO:0007529 | establishment of synaptic specificity at neuromuscular junction(GO:0007529) |
| 0.4 | 4.7 | GO:0045176 | apical protein localization(GO:0045176) |
| 0.2 | 4.6 | GO:0050667 | homocysteine metabolic process(GO:0050667) |
| 0.0 | 4.5 | GO:0042787 | protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 12.8 | GO:0030673 | axolemma(GO:0030673) |
| 0.1 | 10.7 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.9 | 7.2 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.0 | 7.1 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.2 | 7.0 | GO:0032588 | trans-Golgi network membrane(GO:0032588) |
| 0.0 | 6.8 | GO:0000151 | ubiquitin ligase complex(GO:0000151) |
| 0.1 | 6.0 | GO:0000118 | histone deacetylase complex(GO:0000118) |
| 0.1 | 5.6 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.1 | 5.0 | GO:0032420 | stereocilium(GO:0032420) |
| 0.4 | 4.8 | GO:0072687 | meiotic spindle(GO:0072687) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.0 | 12.1 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.2 | 10.6 | GO:0070888 | E-box binding(GO:0070888) |
| 0.2 | 7.5 | GO:0003785 | actin monomer binding(GO:0003785) |
| 0.3 | 6.2 | GO:0016864 | protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864) |
| 0.0 | 5.5 | GO:0043130 | ubiquitin binding(GO:0043130) |
| 0.0 | 5.5 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.4 | 5.2 | GO:0035925 | mRNA 3'-UTR AU-rich region binding(GO:0035925) |
| 0.1 | 5.0 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.3 | 4.9 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.2 | 4.8 | GO:0097602 | cullin family protein binding(GO:0097602) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 9.2 | PID RAS PATHWAY | Regulation of Ras family activation |
| 0.1 | 6.0 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.1 | 5.0 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.1 | 4.8 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.2 | 4.4 | PID S1P S1P1 PATHWAY | S1P1 pathway |
| 0.1 | 4.1 | PID HEDGEHOG GLI PATHWAY | Hedgehog signaling events mediated by Gli proteins |
| 0.1 | 3.0 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.1 | 2.9 | ST G ALPHA I PATHWAY | G alpha i Pathway |
| 0.1 | 2.7 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 2.5 | PID AR TF PATHWAY | Regulation of Androgen receptor activity |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 13.5 | REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS | Genes involved in Amino acid and oligopeptide SLC transporters |
| 0.1 | 6.9 | REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES | Genes involved in Transport of vitamins, nucleosides, and related molecules |
| 0.0 | 6.8 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.1 | 5.6 | REACTOME PHASE II CONJUGATION | Genes involved in Phase II conjugation |
| 0.2 | 5.2 | REACTOME RAP1 SIGNALLING | Genes involved in Rap1 signalling |
| 0.1 | 5.0 | REACTOME REGULATION OF BETA CELL DEVELOPMENT | Genes involved in Regulation of beta-cell development |
| 0.4 | 4.9 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.3 | 4.8 | REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.1 | 4.8 | REACTOME METABOLISM OF VITAMINS AND COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 4.5 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |