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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Tfap2b

Z-value: 1.12

Motif logo

Transcription factors associated with Tfap2b

Gene Symbol Gene ID Gene Info
ENSMUSG00000025927.7 transcription factor AP-2 beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfap2bmm10_v2_chr1_+_19212054_192121060.372.6e-02Click!

Activity profile of Tfap2b motif

Sorted Z-values of Tfap2b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_102365111 6.20 ENSMUST00000006749.9
solute carrier family 4 (anion exchanger), member 1
chr12_-_76709997 5.61 ENSMUST00000166101.1
spectrin beta, erythrocytic
chr4_-_140774196 5.11 ENSMUST00000026381.6
peptidyl arginine deiminase, type IV
chr3_-_84480419 4.55 ENSMUST00000107689.1
FH2 domain containing 1
chr2_-_131160006 4.02 ENSMUST00000103188.3
ENSMUST00000133602.1
ENSMUST00000028800.5
RIKEN cDNA 1700037H04 gene
chr7_-_45526146 2.46 ENSMUST00000167273.1
ENSMUST00000042105.8
protein phosphatase 1, regulatory (inhibitor) subunit 15A
chr12_+_102129019 2.34 ENSMUST00000079020.4
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr3_-_132950043 2.33 ENSMUST00000117164.1
ENSMUST00000093971.4
ENSMUST00000042729.9
ENSMUST00000042744.9
ENSMUST00000117811.1
nephronectin
chr11_-_70255329 2.25 ENSMUST00000108574.2
ENSMUST00000000329.2
arachidonate 12-lipoxygenase
chr11_+_35121126 2.04 ENSMUST00000069837.3
slit homolog 3 (Drosophila)
chr17_+_33555719 2.03 ENSMUST00000087605.5
ENSMUST00000174695.1
myosin IF
chr3_-_137981523 2.01 ENSMUST00000136613.1
ENSMUST00000029806.6
dual adaptor for phosphotyrosine and 3-phosphoinositides 1
chr7_-_98162318 1.96 ENSMUST00000107112.1
calpain 5
chr1_-_96872165 1.95 ENSMUST00000071985.4
solute carrier organic anion transporter family, member 4C1
chr8_+_79028317 1.94 ENSMUST00000087927.4
ENSMUST00000098614.2
zinc finger protein 827
chr2_+_119742306 1.89 ENSMUST00000028758.7
inositol 1,4,5-trisphosphate 3-kinase A
chr6_-_124733067 1.86 ENSMUST00000173647.1
protein tyrosine phosphatase, non-receptor type 6
chr15_-_97831460 1.85 ENSMUST00000079838.7
ENSMUST00000118294.1
histone deacetylase 7
chr17_+_34914459 1.85 ENSMUST00000007249.8
solute carrier family 44, member 4
chr11_-_99493112 1.81 ENSMUST00000006969.7
keratin 23
chr7_-_80387935 1.78 ENSMUST00000080932.6
feline sarcoma oncogene
chrX_+_49470450 1.76 ENSMUST00000114904.3
Rho GTPase activating protein 36
chr17_-_25952565 1.76 ENSMUST00000162431.1
RIKEN cDNA A930017K11 gene
chrX_+_49470555 1.73 ENSMUST00000042444.6
Rho GTPase activating protein 36
chr12_+_102128718 1.71 ENSMUST00000159329.1
solute carrier family 24 (sodium/potassium/calcium exchanger), member 4
chr7_-_142969238 1.70 ENSMUST00000009392.4
ENSMUST00000121862.1
achaete-scute complex homolog 2 (Drosophila)
chrX_-_104671048 1.68 ENSMUST00000042070.5
zinc finger, DHHC domain containing 15
chr6_-_37299950 1.66 ENSMUST00000101532.3
diacylglycerol kinase, iota
chr7_+_25686994 1.50 ENSMUST00000002678.9
transforming growth factor, beta 1
chr16_-_22163299 1.48 ENSMUST00000100052.4
insulin-like growth factor 2 mRNA binding protein 2
chr19_+_38055002 1.45 ENSMUST00000096096.4
ENSMUST00000116506.1
ENSMUST00000169673.1
centrosomal protein 55
chrX_+_159627534 1.45 ENSMUST00000073094.3
SH3-domain kinase binding protein 1
chr4_-_136956784 1.43 ENSMUST00000030420.8
Eph receptor A8
chr5_-_24329556 1.42 ENSMUST00000115098.2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr8_+_105297663 1.38 ENSMUST00000015003.8
E2F transcription factor 4
chr14_-_67715585 1.36 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
cell division cycle associated 2
chr9_-_14751987 1.35 ENSMUST00000061498.5
fucosyltransferase 4
chr7_+_29134971 1.34 ENSMUST00000160194.1
RAS guanyl releasing protein 4
chr8_+_84723003 1.32 ENSMUST00000098571.4
RIKEN cDNA G430095P16 gene
chr2_-_164404606 1.29 ENSMUST00000109359.1
ENSMUST00000109358.1
ENSMUST00000103103.3
matrilin 4
chr4_-_133967235 1.29 ENSMUST00000123234.1
high mobility group nucleosomal binding domain 2
chr4_+_127169131 1.27 ENSMUST00000046659.7
discs, large (Drosophila) homolog-associated protein 3
chr13_+_48662989 1.25 ENSMUST00000021813.4
BarH-like homeobox 1
chr5_-_115300912 1.23 ENSMUST00000112090.1
dynein light chain LC8-type 1
chr2_-_127729872 1.22 ENSMUST00000028856.2
mal, T cell differentiation protein-like
chr5_-_115300957 1.15 ENSMUST00000009157.3
dynein light chain LC8-type 1
chr12_+_85686648 1.15 ENSMUST00000040536.5
basic leucine zipper transcription factor, ATF-like
chr9_+_119052863 1.11 ENSMUST00000131647.1
villin-like
chr3_-_65529355 1.09 ENSMUST00000099076.3
RIKEN cDNA 4931440P22 gene
chr4_+_46450892 1.09 ENSMUST00000102926.4
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr4_-_133967296 1.08 ENSMUST00000105893.1
high mobility group nucleosomal binding domain 2
chr18_+_60774675 1.08 ENSMUST00000118551.1
ribosomal protein S14
chr2_+_91945703 1.08 ENSMUST00000178895.1
predicted gene 9821
chr1_+_74791516 1.07 ENSMUST00000006718.8
wingless related MMTV integration site 10a
chr18_+_60774510 1.04 ENSMUST00000025511.3
ribosomal protein S14
chr2_-_181693810 1.04 ENSMUST00000108776.1
ENSMUST00000108771.1
ENSMUST00000108779.1
ENSMUST00000108769.1
ENSMUST00000108772.1
ENSMUST00000002532.2
regulator of G-protein signaling 19
chr2_+_148395369 1.01 ENSMUST00000109962.2
ENSMUST00000047292.2
somatostatin receptor 4
chr7_+_44246722 0.99 ENSMUST00000055858.7
ENSMUST00000107949.1
ENSMUST00000107950.2
ENSMUST00000107948.1
ENSMUST00000084937.4
ENSMUST00000146155.1
RIKEN cDNA 2410002F23 gene
chr9_+_119052770 0.99 ENSMUST00000051386.6
ENSMUST00000074734.6
villin-like
chrX_+_159627265 0.98 ENSMUST00000112456.2
SH3-domain kinase binding protein 1
chr2_-_30830333 0.98 ENSMUST00000041726.3
ankyrin repeat and SOCS box-containing 6
chr16_-_20425881 0.97 ENSMUST00000077867.3
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr7_+_24636566 0.97 ENSMUST00000080718.4
Ly6/Plaur domain containing 3
chr15_+_99579054 0.96 ENSMUST00000023752.4
aquaporin 2
chr17_+_43016536 0.95 ENSMUST00000024708.4
tumor necrosis factor receptor superfamily, member 21
chr2_+_25289899 0.95 ENSMUST00000028337.6
leucine rich repeat containing 26
chr11_+_69655314 0.94 ENSMUST00000047373.5
SRY-box containing gene 15
chr1_-_136234113 0.93 ENSMUST00000120339.1
ENSMUST00000048668.8
RIKEN cDNA 5730559C18 gene
chr9_-_57262591 0.93 ENSMUST00000034846.5
RIKEN cDNA 1700017B05 gene
chr6_+_91515928 0.92 ENSMUST00000040607.4
LSM3 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr7_+_29134854 0.91 ENSMUST00000161522.1
ENSMUST00000159975.1
ENSMUST00000032811.5
ENSMUST00000094617.4
RAS guanyl releasing protein 4
chr11_+_69965396 0.91 ENSMUST00000018713.6
claudin 7
chr17_-_35700520 0.91 ENSMUST00000119825.1
discoidin domain receptor family, member 1
chr4_-_133967893 0.90 ENSMUST00000100472.3
ENSMUST00000136327.1
high mobility group nucleosomal binding domain 2
chr7_+_58658181 0.90 ENSMUST00000168747.1
ATPase, class V, type 10A
chr4_+_109978004 0.89 ENSMUST00000061187.3
doublesex and mab-3 related transcription factor like family A2
chr1_+_34801704 0.89 ENSMUST00000047664.9
Rho guanine nucleotide exchange factor (GEF) 4
chr18_+_60925612 0.87 ENSMUST00000102888.3
ENSMUST00000025519.4
calcium/calmodulin-dependent protein kinase II alpha
chr7_+_141447645 0.87 ENSMUST00000106004.1
ENSMUST00000106003.1
ribosomal protein, large P2
chr11_+_32533290 0.83 ENSMUST00000102821.3
serine/threonine kinase 10
chr11_-_96977660 0.82 ENSMUST00000107626.1
ENSMUST00000107624.1
Sp2 transcription factor
chr7_-_126447642 0.81 ENSMUST00000146973.1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr9_+_37489281 0.80 ENSMUST00000048604.6
Myb/SANT-like DNA-binding domain containing 2
chr17_+_34590162 0.79 ENSMUST00000173772.1
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr11_-_94242701 0.78 ENSMUST00000061469.3
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr17_+_34589799 0.78 ENSMUST00000038244.8
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr1_-_135105210 0.77 ENSMUST00000044828.7
leucine-rich repeat-containing G protein-coupled receptor 6
chr8_+_105605220 0.76 ENSMUST00000043531.8
family with sequence similarity 65, member A
chr5_+_52582320 0.75 ENSMUST00000177881.1
predicted gene 5866
chr12_-_111672290 0.73 ENSMUST00000001304.7
creatine kinase, brain
chr10_-_59951753 0.73 ENSMUST00000020308.3
DNA-damage-inducible transcript 4
chr2_+_25262589 0.73 ENSMUST00000114336.3
taperin
chr11_+_121259983 0.71 ENSMUST00000106113.1
forkhead box K2
chr11_+_5861886 0.69 ENSMUST00000102923.3
AE binding protein 1
chr1_+_55406163 0.69 ENSMUST00000042986.8
phospholipase C-like 1
chr2_+_158610731 0.69 ENSMUST00000045738.4
solute carrier family 32 (GABA vesicular transporter), member 1
chr15_-_79834224 0.68 ENSMUST00000109623.1
ENSMUST00000109625.1
ENSMUST00000023060.6
ENSMUST00000089299.5
chromobox 6
neuronal pentraxin chromo domain
chr11_+_98386450 0.67 ENSMUST00000041301.7
phenylethanolamine-N-methyltransferase
chr5_-_103629279 0.66 ENSMUST00000031263.1
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr1_+_74771886 0.66 ENSMUST00000006716.6
wingless-related MMTV integration site 6
chrX_+_9272756 0.66 ENSMUST00000015486.6
Kell blood group precursor (McLeod phenotype) homolog
chrX_+_162760427 0.65 ENSMUST00000112326.1
retinoblastoma binding protein 7
chr12_+_108410625 0.65 ENSMUST00000109857.1
echinoderm microtubule associated protein like 1
chr19_-_46039621 0.65 ENSMUST00000056931.7
LIM domain binding 1
chr13_+_55464237 0.65 ENSMUST00000046533.7
proline rich 7 (synaptic)
chr15_-_99370427 0.64 ENSMUST00000081224.7
ENSMUST00000120633.1
ENSMUST00000088233.6
formin-like 3
chr4_-_133967953 0.63 ENSMUST00000102553.4
high mobility group nucleosomal binding domain 2
chr12_+_17690793 0.63 ENSMUST00000071858.3
hippocalcin-like 1
chr15_+_100761741 0.63 ENSMUST00000023776.6
solute carrier family 4 (anion exchanger), member 8
chr1_+_135766085 0.62 ENSMUST00000038945.5
pleckstrin homology-like domain, family A, member 3
chr7_-_45466894 0.61 ENSMUST00000033093.8
BCL2-associated X protein
chr15_-_79834261 0.60 ENSMUST00000148358.1
chromobox 6
chr9_+_54699514 0.60 ENSMUST00000154690.1
DnaJ (Hsp40) homolog, subfamily A, member 4
chr15_-_75747922 0.60 ENSMUST00000062002.4
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr12_-_15816762 0.59 ENSMUST00000020922.7
tribbles homolog 2 (Drosophila)
chr2_-_11502090 0.58 ENSMUST00000179584.1
ENSMUST00000170196.2
ENSMUST00000171188.2
ENSMUST00000114845.3
ENSMUST00000114844.1
ENSMUST00000100411.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr14_+_20674311 0.58 ENSMUST00000048657.8
Sec24 related gene family, member C (S. cerevisiae)
chr9_+_54699548 0.58 ENSMUST00000070070.7
DnaJ (Hsp40) homolog, subfamily A, member 4
chrX_+_151047170 0.56 ENSMUST00000026296.7
FYVE, RhoGEF and PH domain containing 1
chr19_+_4099998 0.55 ENSMUST00000049658.7
phosphatidylinositol transfer protein, membrane-associated 1
chr7_-_30914327 0.55 ENSMUST00000040548.7
myelin-associated glycoprotein
chr11_-_100414829 0.55 ENSMUST00000066489.6
leprecan-like 4
chr2_+_155956537 0.53 ENSMUST00000109619.2
ENSMUST00000039994.7
ENSMUST00000094421.4
ENSMUST00000151569.1
ENSMUST00000109618.1
centrosomal protein 250
chr4_+_109406623 0.53 ENSMUST00000124209.1
tetratricopeptide repeat domain 39A
chr2_+_74697663 0.52 ENSMUST00000059272.8
homeobox D9
chr12_+_108410542 0.51 ENSMUST00000054955.7
echinoderm microtubule associated protein like 1
chr11_-_58168467 0.51 ENSMUST00000172035.1
ENSMUST00000035604.6
ENSMUST00000102711.2
gem (nuclear organelle) associated protein 5
chr7_+_45526330 0.51 ENSMUST00000120985.1
ENSMUST00000051810.8
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr14_-_30607808 0.50 ENSMUST00000112207.1
ENSMUST00000112206.1
ENSMUST00000112202.1
ENSMUST00000112203.1
protein kinase C, delta
chr3_-_57847478 0.50 ENSMUST00000120289.1
ENSMUST00000066882.8
profilin 2
chr14_+_79451791 0.49 ENSMUST00000100359.1
kelch repeat and BTB (POZ) domain containing 6
chr8_-_122678072 0.49 ENSMUST00000006525.7
ENSMUST00000064674.6
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr2_-_24475097 0.48 ENSMUST00000149294.1
ENSMUST00000153535.1
paired box gene 8
chr6_-_124733121 0.48 ENSMUST00000112484.3
protein tyrosine phosphatase, non-receptor type 6
chr2_-_11502067 0.48 ENSMUST00000028114.6
ENSMUST00000049849.6
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr4_-_133753611 0.48 ENSMUST00000145664.2
ENSMUST00000105897.3
AT rich interactive domain 1A (SWI-like)
chr10_-_119240006 0.48 ENSMUST00000020315.6
cullin associated and neddylation disassociated 1
chr3_+_32817520 0.48 ENSMUST00000072312.5
ENSMUST00000108228.1
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr19_+_43440404 0.47 ENSMUST00000165311.1
cyclin M1
chr3_-_27710413 0.47 ENSMUST00000046157.4
fibronectin type III domain containing 3B
chr4_-_134238372 0.44 ENSMUST00000030645.8
connector enhancer of kinase suppressor of Ras 1
chrX_+_162760388 0.43 ENSMUST00000033720.5
ENSMUST00000112327.1
retinoblastoma binding protein 7
chr9_-_50344981 0.42 ENSMUST00000076364.4
ribosomal protein L10, pseudogene 3
chr17_-_46282991 0.42 ENSMUST00000180283.1
ENSMUST00000012440.6
ENSMUST00000164342.2
tight junction associated protein 1
chr2_+_22895583 0.41 ENSMUST00000152170.1
prenyl (solanesyl) diphosphate synthase, subunit 1
chr15_+_102966794 0.40 ENSMUST00000001699.7
homeobox C10
chr19_+_44757394 0.40 ENSMUST00000004340.4
paired box gene 2
chr2_+_27165233 0.39 ENSMUST00000000910.6
dopamine beta hydroxylase
chr7_-_93081027 0.38 ENSMUST00000098303.1
predicted gene 9934
chr13_+_44731265 0.38 ENSMUST00000173246.1
jumonji, AT rich interactive domain 2
chr7_+_24507122 0.38 ENSMUST00000177205.1
zinc finger protein 428
chr7_+_141079125 0.38 ENSMUST00000159375.1
plakophilin 3
chr12_+_70825492 0.38 ENSMUST00000057859.7
FERM domain containing 6
chr2_-_11502025 0.37 ENSMUST00000114846.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr2_+_130406478 0.36 ENSMUST00000055421.4
transmembrane 239
chr7_-_126503408 0.36 ENSMUST00000040202.8
ataxin 2-like
chr2_-_25580099 0.35 ENSMUST00000114217.1
predicted gene 996
chr17_+_35841491 0.35 ENSMUST00000082337.6
mediator of DNA damage checkpoint 1
chr1_-_14755966 0.34 ENSMUST00000027062.5
musculin
chr10_+_39420009 0.34 ENSMUST00000157009.1
Fyn proto-oncogene
chr19_-_6015769 0.34 ENSMUST00000164843.1
calpain 1
chr4_+_123183722 0.34 ENSMUST00000152194.1
hippocalcin-like 4
chr2_-_131086765 0.33 ENSMUST00000028794.3
ENSMUST00000110227.1
ENSMUST00000110226.1
sialic acid binding Ig-like lectin 1, sialoadhesin
chr1_+_131750485 0.31 ENSMUST00000147800.1
solute carrier family 26, member 9
chr2_-_92024502 0.30 ENSMUST00000028663.4
cAMP responsive element binding protein 3-like 1
chr15_-_101924725 0.29 ENSMUST00000023797.6
keratin 4
chr15_-_79834323 0.28 ENSMUST00000177316.2
ENSMUST00000175858.2
neuronal pentraxin receptor
chr10_-_127211528 0.28 ENSMUST00000013970.7
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr13_-_9878998 0.28 ENSMUST00000063093.9
cholinergic receptor, muscarinic 3, cardiac
chr19_+_6364557 0.28 ENSMUST00000155973.1
splicing factor 1
chr16_-_92358874 0.28 ENSMUST00000166707.1
potassium voltage-gated channel, Isk-related subfamily, member 1
chr19_-_53038534 0.28 ENSMUST00000183274.1
ENSMUST00000182097.1
ENSMUST00000069988.8
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr7_+_25282179 0.27 ENSMUST00000163320.1
ENSMUST00000005578.6
capicua homolog (Drosophila)
chr2_-_179976646 0.26 ENSMUST00000041618.7
TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_-_172043466 0.25 ENSMUST00000087950.3
cerebellin 4 precursor protein
chr6_+_88465409 0.25 ENSMUST00000032165.9
RuvB-like protein 1
chr4_+_133176336 0.25 ENSMUST00000105912.1
WAS protein family, member 2
chr17_-_32284715 0.25 ENSMUST00000127893.1
bromodomain containing 4
chr15_+_103018936 0.24 ENSMUST00000165375.1
homeobox C4
chr5_+_30913398 0.24 ENSMUST00000031055.5
elastin microfibril interfacer 1
chr4_+_8690399 0.23 ENSMUST00000127476.1
chromodomain helicase DNA binding protein 7
chr15_-_38300693 0.23 ENSMUST00000074043.5
Kruppel-like factor 10
chr13_+_12702362 0.23 ENSMUST00000104944.2
predicted gene 2399
chr17_+_34898931 0.22 ENSMUST00000097342.3
ENSMUST00000013931.5
euchromatic histone lysine N-methyltransferase 2
chr17_-_12992188 0.22 ENSMUST00000159986.1
Wilms' tumour 1-associating protein
chr6_-_24956106 0.21 ENSMUST00000127247.2
transmembrane protein 229A
chr8_+_105413614 0.21 ENSMUST00000109355.2
leucine rich repeat containing 36
chr17_-_70849644 0.21 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
TGFB-induced factor homeobox 1
chr16_+_20629842 0.21 ENSMUST00000122306.1
ENSMUST00000133344.1
endothelin converting enzyme 2
chr1_-_143702832 0.21 ENSMUST00000018337.7
cell division cycle 73, Paf1/RNA polymerase II complex component
chr15_-_11905609 0.20 ENSMUST00000066529.3
natriuretic peptide receptor 3
chr11_-_95146263 0.20 ENSMUST00000021241.6
distal-less homeobox 4
chr11_+_102189620 0.20 ENSMUST00000070334.3
ENSMUST00000078975.7
glucose 6 phosphatase, catalytic, 3
chrX_+_73757069 0.20 ENSMUST00000002079.6
plexin B3
chr4_+_43875524 0.20 ENSMUST00000030198.6
reversion-inducing-cysteine-rich protein with kazal motifs
chr19_+_6975048 0.17 ENSMUST00000070850.6
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr13_+_44731281 0.16 ENSMUST00000174086.1
jumonji, AT rich interactive domain 2
chr3_+_89831352 0.16 ENSMUST00000050401.5
src homology 2 domain-containing transforming protein E
chr8_+_104540800 0.16 ENSMUST00000056051.4
carbonic anhydrase 7
chr10_-_7663245 0.16 ENSMUST00000163085.1
ENSMUST00000159917.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.8 2.5 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.6 1.8 GO:0008292 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.6 2.3 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.5 1.5 GO:0044413 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment(GO:0002362) evasion or tolerance of host defenses by virus(GO:0019049) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834) negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.5 2.3 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.5 2.3 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.4 2.0 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.4 1.4 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.3 1.0 GO:0071462 cellular response to mercury ion(GO:0071288) cellular response to water stimulus(GO:0071462)
0.3 0.9 GO:0048627 positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) myoblast development(GO:0048627)
0.3 0.6 GO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.3 1.7 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.3 1.1 GO:0010286 heat acclimation(GO:0010286)
0.3 0.8 GO:0032470 positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076)
0.3 0.8 GO:1990523 bone regeneration(GO:1990523)
0.2 1.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.2 6.2 GO:0014823 response to activity(GO:0014823)
0.2 0.7 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.2 0.2 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.2 0.6 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2 4.0 GO:0097186 amelogenesis(GO:0097186)
0.2 1.7 GO:0046959 habituation(GO:0046959)
0.2 0.6 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.2 1.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.2 0.5 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 1.9 GO:0006020 inositol metabolic process(GO:0006020)
0.2 2.0 GO:0043312 neutrophil degranulation(GO:0043312)
0.2 1.2 GO:0001766 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.9 GO:2000594 pronephric field specification(GO:0039003) pattern specification involved in pronephros development(GO:0039017) kidney field specification(GO:0072004) regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072304) negative regulation of mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:0072305) apoptotic process involved in metanephric collecting duct development(GO:1900204) apoptotic process involved in metanephric nephron tubule development(GO:1900205) regulation of apoptotic process involved in metanephric collecting duct development(GO:1900214) negative regulation of apoptotic process involved in metanephric collecting duct development(GO:1900215) regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900217) negative regulation of apoptotic process involved in metanephric nephron tubule development(GO:1900218) mesenchymal cell apoptotic process involved in metanephric nephron morphogenesis(GO:1901147) regulation of metanephric DCT cell differentiation(GO:2000592) positive regulation of metanephric DCT cell differentiation(GO:2000594)
0.1 0.9 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.1 1.4 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 2.4 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.1 7.7 GO:0051693 actin filament capping(GO:0051693)
0.1 0.7 GO:0042414 epinephrine metabolic process(GO:0042414)
0.1 0.5 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 3.9 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.1 0.4 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.1 1.9 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 0.3 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.7 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 1.6 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 1.2 GO:0045820 negative regulation of glycolytic process(GO:0045820)
0.1 0.5 GO:0060697 glucosylceramide catabolic process(GO:0006680) positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.7 GO:0098700 neurotransmitter loading into synaptic vesicle(GO:0098700)
0.1 1.2 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.1 1.7 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.1 2.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.1 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.1 0.7 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.9 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.1 1.1 GO:0048733 sebaceous gland development(GO:0048733)
0.1 1.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.1 0.7 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 1.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 1.5 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 0.8 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 0.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.2 GO:0036166 phenotypic switching(GO:0036166) cellular response to cocaine(GO:0071314)
0.1 1.6 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.1 0.5 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.1 0.2 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684)
0.1 0.4 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.4 GO:0003383 apical constriction(GO:0003383)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221) atrioventricular canal development(GO:0036302)
0.1 0.3 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.1 GO:0061317 canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.1 0.5 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.2 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.1 0.2 GO:1902460 transforming growth factor beta activation(GO:0036363) regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 0.9 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.3 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.0 1.9 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.5 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:0080009 mRNA methylation(GO:0080009)
0.0 1.3 GO:0033962 cytoplasmic mRNA processing body assembly(GO:0033962)
0.0 0.2 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.3 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.2 GO:0060214 endocardium formation(GO:0060214)
0.0 0.5 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.3 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.0 0.3 GO:0010756 box C/D snoRNP assembly(GO:0000492) positive regulation of plasminogen activation(GO:0010756)
0.0 0.5 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.1 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.5 GO:0031643 positive regulation of myelination(GO:0031643)
0.0 1.3 GO:0048536 spleen development(GO:0048536)
0.0 1.8 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.6 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 1.2 GO:0030815 negative regulation of cAMP metabolic process(GO:0030815)
0.0 0.2 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.0 1.1 GO:0021591 ventricular system development(GO:0021591)
0.0 1.4 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.3 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.3 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.9 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 1.2 GO:0007405 neuroblast proliferation(GO:0007405)
0.0 0.1 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.8 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.2 GO:0001711 endodermal cell fate commitment(GO:0001711)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.9 GO:0006414 translational elongation(GO:0006414)
0.0 0.3 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.3 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:0060744 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.1 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 2.4 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.8 GO:0048678 response to axon injury(GO:0048678)
0.0 0.9 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:0007000 nucleolus organization(GO:0007000)
0.0 1.4 GO:0051028 mRNA transport(GO:0051028)
0.0 0.7 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.6 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.2 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 5.2 GO:0008091 spectrin(GO:0008091)
0.4 1.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.3 2.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.3 2.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 0.9 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.2 1.0 GO:0031310 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.2 2.5 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.1 2.4 GO:1904115 axon cytoplasm(GO:1904115)
0.1 0.9 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.4 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.1 1.5 GO:0090543 Flemming body(GO:0090543)
0.1 1.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.1 0.6 GO:0031673 H zone(GO:0031673)
0.1 1.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.4 GO:0036396 MIS complex(GO:0036396)
0.1 0.4 GO:0005914 spot adherens junction(GO:0005914)
0.1 0.5 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.1 1.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.3 GO:0044316 cone cell pedicle(GO:0044316)
0.1 6.2 GO:0014704 intercalated disc(GO:0014704)
0.1 0.6 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 1.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.4 GO:0019907 cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0032797 SMN complex(GO:0032797)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 1.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 2.0 GO:0031941 filamentous actin(GO:0031941)
0.0 0.7 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 1.2 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.1 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.0 0.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 2.0 GO:0005882 intermediate filament(GO:0005882)
0.0 2.3 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.7 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 2.0 GO:0030139 endocytic vesicle(GO:0030139)
0.0 1.5 GO:0005902 microvillus(GO:0005902)
0.0 1.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 2.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 2.6 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 1.9 GO:0043197 dendritic spine(GO:0043197)
0.0 0.9 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.7 4.0 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.6 2.3 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.4 1.5 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.3 6.8 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 1.7 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 0.9 GO:0030629 U6 snRNA 3'-end binding(GO:0030629)
0.3 2.3 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.3 1.8 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.3 2.0 GO:0048495 Roundabout binding(GO:0048495)
0.2 1.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.2 1.9 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.2 1.4 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 1.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 2.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 1.4 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 1.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 2.4 GO:0030235 nitric-oxide synthase regulator activity(GO:0030235)
0.1 0.7 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.1 1.0 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 5.2 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.4 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 0.5 GO:0070976 TIR domain binding(GO:0070976)
0.1 0.7 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.5 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 0.4 GO:0000010 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 0.9 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 0.5 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 1.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 2.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.1 0.3 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.1 2.6 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 1.9 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 1.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 1.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.3 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 2.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.8 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.1 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.1 0.6 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.2 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.1 0.5 GO:0033691 sialic acid binding(GO:0033691)
0.1 0.2 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.6 GO:0030274 LIM domain binding(GO:0030274)
0.1 1.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.1 0.7 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.7 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.1 GO:0005110 frizzled-2 binding(GO:0005110)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.6 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 1.7 GO:0005109 frizzled binding(GO:0005109)
0.0 1.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.0 GO:0043236 laminin binding(GO:0043236)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.0 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.7 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 1.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.0 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 1.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 2.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 1.9 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 0.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 1.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 3.9 GO:0030695 GTPase regulator activity(GO:0030695)
0.0 1.2 GO:0051087 chaperone binding(GO:0051087)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.1 1.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1 1.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.3 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 2.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.1 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 2.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 3.1 PID TGFBR PATHWAY TGF-beta receptor signaling
0.0 1.8 PID RAS PATHWAY Regulation of Ras family activation
0.0 2.0 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 3.3 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.3 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.6 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 1.2 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.1 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.5 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.5 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 1.2 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 2.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 5.2 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 3.2 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.1 11.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.1 0.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.8 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.1 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 2.4 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.1 1.0 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.1 1.1 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 0.9 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 2.2 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.1 1.4 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 2.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 2.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.9 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 2.9 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 1.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.3 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.9 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 1.7 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.9 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 3.7 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 1.0 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.1 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport