Project
avrg: GSE58827: Dynamics of the Mouse Liver
Navigation
Downloads
Results for Smarcc1_Fosl1
Z-value: 1.54
Motif logo
Transcription factors associated with Smarcc1_Fosl1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Fosl1 | mm10_v2_chr19_+_5447692_5447711 | -0.37 | 2.7e-02 | Click! |
| Smarcc1 | mm10_v2_chr9_+_110132015_110132102 | -0.23 | 1.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr9_-_86695897 Show fit | 3.86 |
ENSMUST00000034989.8
|
malic enzyme 1, NADP(+)-dependent, cytosolic |
|
| chr4_-_60582152 Show fit | 3.72 |
ENSMUST00000098047.2
|
major urinary protein 10 |
|
| chr4_-_60421933 Show fit | 3.41 |
ENSMUST00000107506.2
ENSMUST00000122381.1 ENSMUST00000118759.1 ENSMUST00000122177.1 |
major urinary protein 9 |
|
| chr1_+_182564994 Show fit | 3.34 |
ENSMUST00000048941.7
ENSMUST00000168514.1 |
calpain 8 |
|
| chr4_-_61303998 Show fit | 3.33 |
ENSMUST00000071005.8
ENSMUST00000075206.5 |
major urinary protein 14 |
|
| chr4_-_62054112 Show fit | 3.20 |
ENSMUST00000074018.3
|
major urinary protein 20 |
|
| chr4_-_61674094 Show fit | 3.17 |
ENSMUST00000098040.3
|
major urinary protein 18 |
|
| chr4_+_63356152 Show fit | 3.01 |
ENSMUST00000006687.4
|
orosomucoid 3 |
|
| chr19_-_8131982 Show fit | 3.01 |
ENSMUST00000065651.4
|
solute carrier family 22, member 28 |
|
| chr4_-_60222580 Show fit | 2.89 |
ENSMUST00000095058.4
ENSMUST00000163931.1 |
major urinary protein 8 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Smarcc1_Fosl1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 3.7 | GO:0006108 | malate metabolic process(GO:0006108) |
| 0.1 | 3.5 | GO:0035634 | response to stilbenoid(GO:0035634) |
| 0.0 | 3.5 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.5 | 3.2 | GO:0008355 | olfactory learning(GO:0008355) |
| 0.5 | 3.1 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
| 0.2 | 3.1 | GO:0015747 | urate transport(GO:0015747) |
| 0.6 | 2.9 | GO:0009115 | xanthine catabolic process(GO:0009115) |
| 0.2 | 2.9 | GO:0098789 | pre-mRNA cleavage required for polyadenylation(GO:0098789) |
| 0.5 | 2.8 | GO:1902847 | regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 0.3 | 2.8 | GO:0071394 | cellular response to testosterone stimulus(GO:0071394) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.9 | GO:0005740 | mitochondrial envelope(GO:0005740) |
| 0.0 | 5.5 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.3 | 4.4 | GO:0034366 | spherical high-density lipoprotein particle(GO:0034366) |
| 0.0 | 4.0 | GO:0031965 | nuclear membrane(GO:0031965) |
| 1.1 | 3.2 | GO:0097057 | TRAF2-GSTP1 complex(GO:0097057) |
| 0.0 | 3.2 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.0 | 3.1 | GO:0030176 | integral component of endoplasmic reticulum membrane(GO:0030176) |
| 0.1 | 2.9 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
| 0.0 | 2.7 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.8 | 2.5 | GO:0005713 | recombination nodule(GO:0005713) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 6.4 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 6.3 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 1.9 | 5.7 | GO:0005186 | pheromone activity(GO:0005186) |
| 0.2 | 5.4 | GO:1900750 | glutathione binding(GO:0043295) oligopeptide binding(GO:1900750) |
| 0.2 | 5.0 | GO:0005550 | pheromone binding(GO:0005550) |
| 0.0 | 4.2 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.8 | 4.1 | GO:0004031 | aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623) |
| 1.3 | 3.9 | GO:0004470 | malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473) |
| 0.2 | 3.6 | GO:0016290 | palmitoyl-CoA hydrolase activity(GO:0016290) |
| 0.1 | 3.6 | GO:0004521 | endoribonuclease activity(GO:0004521) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 3.3 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.0 | 3.3 | PID P73PATHWAY | p73 transcription factor network |
| 0.1 | 2.7 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.1 | 1.9 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 1.6 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.0 | 1.4 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 1.2 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.0 | 1.0 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 1.0 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.0 | 0.9 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.5 | REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES | Genes involved in Cross-presentation of soluble exogenous antigens (endosomes) |
| 0.1 | 3.6 | REACTOME CHOLESTEROL BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
| 0.2 | 3.2 | REACTOME TRYPTOPHAN CATABOLISM | Genes involved in Tryptophan catabolism |
| 0.0 | 2.7 | REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION | Genes involved in Antigen processing: Ubiquitination & Proteasome degradation |
| 0.1 | 2.4 | REACTOME COMPLEMENT CASCADE | Genes involved in Complement cascade |
| 0.0 | 2.4 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.0 | 2.3 | REACTOME BIOLOGICAL OXIDATIONS | Genes involved in Biological oxidations |
| 0.2 | 2.2 | REACTOME IRAK1 RECRUITS IKK COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.1 | 1.9 | REACTOME CYTOSOLIC TRNA AMINOACYLATION | Genes involved in Cytosolic tRNA aminoacylation |
| 0.1 | 1.7 | REACTOME GAP JUNCTION DEGRADATION | Genes involved in Gap junction degradation |