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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Pou2f2_Pou3f1

Z-value: 1.45

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Transcription factors associated with Pou2f2_Pou3f1

Gene Symbol Gene ID Gene Info
Pou2f2
ENSMUSG00000008496.12 POU domain, class 2, transcription factor 2
Pou3f1
ENSMUSG00000090125.2 POU domain, class 3, transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou3f1mm10_v2_chr4_+_124657646_124657656-0.299.1e-02Click!
Pou2f2mm10_v2_chr7_-_25132473_251325120.222.1e-01Click!

Activity profile of Pou2f2_Pou3f1 motif

Sorted Z-values of Pou2f2_Pou3f1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_23746734 11.16 ENSMUST00000099703.2
Hist1h2bb
histone cluster 1, H2bb
chr3_+_96269695 9.64 ENSMUST00000051089.3
ENSMUST00000177113.1
Hist2h2bb
histone cluster 2, H2bb
chr13_+_21722057 8.82 ENSMUST00000110476.3
Hist1h2bm
histone cluster 1, H2bm
chrX_+_93675088 6.71 ENSMUST00000045898.3
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr11_+_58948890 6.42 ENSMUST00000078267.3
Hist3h2ba
histone cluster 3, H2ba
chr10_-_80421847 5.57 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr7_-_102100227 5.55 ENSMUST00000106937.1
Art5
ADP-ribosyltransferase 5
chr13_-_21833575 5.35 ENSMUST00000081342.5
Hist1h2ap
histone cluster 1, H2ap
chr16_+_17144600 5.07 ENSMUST00000115702.1
Ydjc
YdjC homolog (bacterial)
chr7_+_24507006 5.05 ENSMUST00000176880.1
Zfp428
zinc finger protein 428
chr13_+_22043189 5.03 ENSMUST00000110452.1
Hist1h2bj
histone cluster 1, H2bj
chr13_+_23751069 4.89 ENSMUST00000078369.1
Hist1h2ab
histone cluster 1, H2ab
chr16_-_17144415 4.78 ENSMUST00000115709.1
Ccdc116
coiled-coil domain containing 116
chr5_+_76656512 4.76 ENSMUST00000086909.4
Gm10430
predicted gene 10430
chr2_-_170194033 4.64 ENSMUST00000180625.1
Gm17619
predicted gene, 17619
chr15_-_66831625 4.62 ENSMUST00000164163.1
Sla
src-like adaptor
chr7_+_24507122 4.60 ENSMUST00000177205.1
Zfp428
zinc finger protein 428
chr6_-_67037399 4.59 ENSMUST00000043098.6
Gadd45a
growth arrest and DNA-damage-inducible 45 alpha
chr13_-_23571151 4.56 ENSMUST00000102969.3
Hist1h2ae
histone cluster 1, H2ae
chr13_-_22042949 4.52 ENSMUST00000091741.4
Hist1h2ag
histone cluster 1, H2ag
chr14_+_27000362 4.45 ENSMUST00000035433.8
Hesx1
homeobox gene expressed in ES cells
chr13_-_23683941 4.42 ENSMUST00000171127.1
Hist1h2ac
histone cluster 1, H2ac
chr11_+_95337012 4.00 ENSMUST00000037502.6
Fam117a
family with sequence similarity 117, member A
chr7_+_24507057 3.91 ENSMUST00000071361.6
Zfp428
zinc finger protein 428
chr13_+_23544052 3.90 ENSMUST00000075558.2
Hist1h3f
histone cluster 1, H3f
chr3_+_51661167 3.79 ENSMUST00000099106.3
Mgst2
microsomal glutathione S-transferase 2
chr19_+_47228804 3.76 ENSMUST00000111807.3
Neurl1a
neuralized homolog 1A (Drosophila)
chr12_-_36042476 3.63 ENSMUST00000020896.8
Tspan13
tetraspanin 13
chr11_+_58954675 3.56 ENSMUST00000108817.3
ENSMUST00000047697.5
Hist3h2a
Trim17
histone cluster 3, H2a
tripartite motif-containing 17
chr11_-_69605829 3.51 ENSMUST00000047889.6
Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr8_+_22974844 3.50 ENSMUST00000110688.2
ENSMUST00000121802.2
Ank1
ankyrin 1, erythroid
chr1_+_91540553 3.45 ENSMUST00000027538.7
Asb1
ankyrin repeat and SOCS box-containing 1
chr10_+_75948292 3.35 ENSMUST00000000926.2
Vpreb3
pre-B lymphocyte gene 3
chrX_+_56454871 3.27 ENSMUST00000039374.2
ENSMUST00000101553.2
Ddx26b
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr7_+_126776939 3.15 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3
yippee-like 3 (Drosophila)
chr1_-_89933290 3.10 ENSMUST00000036954.7
Gbx2
gastrulation brain homeobox 2
chr13_+_22035821 3.00 ENSMUST00000110455.2
Hist1h2bk
histone cluster 1, H2bk
chr6_-_56901870 2.74 ENSMUST00000101367.2
Nt5c3
5'-nucleotidase, cytosolic III
chr12_-_114416895 2.68 ENSMUST00000179796.1
Ighv6-5
immunoglobulin heavy variable V6-5
chr13_-_22035589 2.67 ENSMUST00000091742.4
Hist1h2ah
histone cluster 1, H2ah
chr13_+_23574381 2.64 ENSMUST00000090776.4
Hist1h2ad
histone cluster 1, H2ad
chr17_+_27556641 2.62 ENSMUST00000119486.1
ENSMUST00000118599.1
Hmga1
high mobility group AT-hook 1
chr5_+_76840597 2.60 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
C530008M17Rik
RIKEN cDNA C530008M17 gene
chr17_+_27556668 2.59 ENSMUST00000117254.1
ENSMUST00000118570.1
Hmga1
high mobility group AT-hook 1
chr7_+_45017953 2.55 ENSMUST00000044111.7
Rras
Harvey rat sarcoma oncogene, subgroup R
chr7_+_24507099 2.50 ENSMUST00000177228.1
Zfp428
zinc finger protein 428
chr17_+_27556613 2.47 ENSMUST00000117600.1
ENSMUST00000114888.3
Hmga1
high mobility group AT-hook 1
chr9_+_21936986 2.45 ENSMUST00000046371.6
BC018242
cDNA sequence BC018242
chr13_+_21810428 2.43 ENSMUST00000091745.5
Hist1h2ao
histone cluster 1, H2ao
chr4_-_128806045 2.43 ENSMUST00000106072.2
ENSMUST00000170934.1
Zfp362
zinc finger protein 362
chrX_+_133850980 2.41 ENSMUST00000033602.8
Tnmd
tenomodulin
chr16_-_92697315 2.33 ENSMUST00000168195.1
ENSMUST00000113956.3
Runx1
runt related transcription factor 1
chr7_-_102099932 2.33 ENSMUST00000106934.1
Art5
ADP-ribosyltransferase 5
chr2_+_25180737 2.31 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr15_+_62039216 2.26 ENSMUST00000183297.1
Pvt1
plasmacytoma variant translocation 1
chr2_-_152398046 2.25 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12
SRY-box containing gene 12
chr13_+_23533869 2.23 ENSMUST00000073261.2
Hist1h2af
histone cluster 1, H2af
chr11_-_106314494 2.21 ENSMUST00000167143.1
Cd79b
CD79B antigen
chr4_-_140810646 2.20 ENSMUST00000026377.2
Padi3
peptidyl arginine deiminase, type III
chr3_+_83766300 2.17 ENSMUST00000029625.7
Sfrp2
secreted frizzled-related protein 2
chr7_+_127746775 2.15 ENSMUST00000033081.7
Fbxl19
F-box and leucine-rich repeat protein 19
chr5_+_137629169 2.12 ENSMUST00000176667.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr4_+_152039315 2.07 ENSMUST00000084116.6
ENSMUST00000105663.1
ENSMUST00000103197.3
Nol9
nucleolar protein 9
chr2_+_119047116 2.05 ENSMUST00000152380.1
ENSMUST00000099542.2
Casc5
cancer susceptibility candidate 5
chr7_+_98838845 1.96 ENSMUST00000167303.1
Wnt11
wingless-related MMTV integration site 11
chr16_-_92826004 1.91 ENSMUST00000023673.7
Runx1
runt related transcription factor 1
chr1_-_144567667 1.91 ENSMUST00000184008.1
Rgs21
regulator of G-protein signalling 21
chr9_-_70421533 1.89 ENSMUST00000034742.6
Ccnb2
cyclin B2
chrX_-_167209149 1.88 ENSMUST00000112176.1
Tmsb4x
thymosin, beta 4, X chromosome
chr3_-_50443603 1.85 ENSMUST00000029297.4
Slc7a11
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr3_+_159495408 1.85 ENSMUST00000120272.1
ENSMUST00000029825.7
ENSMUST00000106041.2
Depdc1a
DEP domain containing 1a
chr13_+_5861489 1.84 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr14_-_79771305 1.83 ENSMUST00000039568.5
Pcdh8
protocadherin 8
chr5_+_137630116 1.82 ENSMUST00000175968.1
Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr16_-_19883873 1.73 ENSMUST00000100083.3
A930003A15Rik
RIKEN cDNA A930003A15 gene
chr12_-_79192248 1.71 ENSMUST00000161204.1
Rdh11
retinol dehydrogenase 11
chr4_-_3938354 1.69 ENSMUST00000003369.3
Plag1
pleiomorphic adenoma gene 1
chr9_+_71215779 1.68 ENSMUST00000034723.5
Aldh1a2
aldehyde dehydrogenase family 1, subfamily A2
chr17_-_58991343 1.67 ENSMUST00000025064.7
2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr10_+_79927039 1.66 ENSMUST00000019708.5
ENSMUST00000105377.1
Arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr19_+_8941865 1.65 ENSMUST00000096240.2
Mta2
metastasis-associated gene family, member 2
chr10_+_79927330 1.65 ENSMUST00000105376.1
Arid3a
AT rich interactive domain 3A (BRIGHT-like)
chr2_+_119047129 1.64 ENSMUST00000153300.1
ENSMUST00000028799.5
Casc5
cancer susceptibility candidate 5
chr3_+_92365178 1.63 ENSMUST00000050397.1
Sprr2f
small proline-rich protein 2F
chr14_-_66868572 1.62 ENSMUST00000022629.8
Dpysl2
dihydropyrimidinase-like 2
chr3_-_144849301 1.60 ENSMUST00000159989.1
Clca4
chloride channel calcium activated 4
chr6_+_136518820 1.59 ENSMUST00000032335.6
Atf7ip
activating transcription factor 7 interacting protein
chr19_-_46044914 1.58 ENSMUST00000026252.7
Ldb1
LIM domain binding 1
chr13_+_21833736 1.57 ENSMUST00000180288.1
ENSMUST00000110467.1
Hist1h2br
histone cluster 1 H2br
chr6_-_148946146 1.57 ENSMUST00000132696.1
Fam60a
family with sequence similarity 60, member A
chr6_-_52240841 1.56 ENSMUST00000121043.1
Hoxa10
homeobox A10
chr3_+_130180882 1.54 ENSMUST00000106353.1
ENSMUST00000080335.4
Col25a1
collagen, type XXV, alpha 1
chr5_-_147307264 1.53 ENSMUST00000031650.3
Cdx2
caudal type homeobox 2
chr2_-_160912292 1.53 ENSMUST00000109454.1
ENSMUST00000057169.4
Emilin3
elastin microfibril interfacer 3
chr7_-_143460989 1.52 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c
cyclin-dependent kinase inhibitor 1C (P57)
chr13_-_21787218 1.52 ENSMUST00000091751.2
Hist1h2an
histone cluster 1, H2an
chr19_-_46045194 1.51 ENSMUST00000156585.1
ENSMUST00000152946.1
Ldb1
LIM domain binding 1
chr12_-_114406773 1.49 ENSMUST00000177949.1
Ighv6-4
immunoglobulin heavy variable V6-4
chr4_-_152477433 1.49 ENSMUST00000159186.1
ENSMUST00000162017.1
ENSMUST00000030768.2
Kcnab2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr8_+_120488416 1.46 ENSMUST00000034279.9
Gse1
genetic suppressor element 1
chr6_-_13839916 1.46 ENSMUST00000060442.7
Gpr85
G protein-coupled receptor 85
chr6_+_145145473 1.46 ENSMUST00000156849.1
ENSMUST00000132948.1
Lrmp
lymphoid-restricted membrane protein
chr2_+_160645881 1.45 ENSMUST00000109468.2
Top1
topoisomerase (DNA) I
chr11_+_61208621 1.45 ENSMUST00000108716.1
ENSMUST00000019246.3
Aldh3a1
aldehyde dehydrogenase family 3, subfamily A1
chr11_+_96282529 1.44 ENSMUST00000125410.1
Hoxb8
homeobox B8
chr16_+_91729281 1.44 ENSMUST00000114001.1
ENSMUST00000113999.1
ENSMUST00000064797.5
ENSMUST00000114002.2
ENSMUST00000095909.3
ENSMUST00000056482.7
ENSMUST00000113996.1
Itsn1
intersectin 1 (SH3 domain protein 1A)
chr8_-_122460666 1.38 ENSMUST00000006762.5
Snai3
snail homolog 3 (Drosophila)
chr3_+_92316705 1.36 ENSMUST00000061038.2
Sprr2b
small proline-rich protein 2B
chr9_-_22389113 1.35 ENSMUST00000040912.7
Anln
anillin, actin binding protein
chr17_+_29490812 1.34 ENSMUST00000024811.6
Pim1
proviral integration site 1
chr12_-_17324703 1.33 ENSMUST00000020884.9
ENSMUST00000095820.5
ENSMUST00000127185.1
Atp6v1c2
ATPase, H+ transporting, lysosomal V1 subunit C2
chr7_+_82174796 1.31 ENSMUST00000032874.7
Sh3gl3
SH3-domain GRB2-like 3
chr11_-_34833631 1.30 ENSMUST00000093191.2
Spdl1
spindle apparatus coiled-coil protein 1
chr2_-_152830266 1.29 ENSMUST00000140436.1
Bcl2l1
BCL2-like 1
chr5_-_123865491 1.26 ENSMUST00000057145.5
Niacr1
niacin receptor 1
chr6_+_129350237 1.25 ENSMUST00000065289.4
Clec12a
C-type lectin domain family 12, member a
chr4_+_129960760 1.25 ENSMUST00000139884.1
1700003M07Rik
RIKEN cDNA 1700003M07 gene
chr5_-_65091584 1.25 ENSMUST00000043352.4
Tmem156
transmembrane protein 156
chr2_-_152830615 1.24 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
Bcl2l1
BCL2-like 1
chr11_+_96282648 1.23 ENSMUST00000168043.1
Hoxb8
homeobox B8
chr2_-_102451792 1.21 ENSMUST00000099678.3
Fjx1
four jointed box 1 (Drosophila)
chr8_-_70234401 1.15 ENSMUST00000019679.5
Armc6
armadillo repeat containing 6
chr11_-_96747405 1.13 ENSMUST00000180492.1
2010300F17Rik
RIKEN cDNA 2010300F17 gene
chr1_+_52008210 1.12 ENSMUST00000027277.5
Stat4
signal transducer and activator of transcription 4
chr7_+_25282179 1.11 ENSMUST00000163320.1
ENSMUST00000005578.6
Cic
capicua homolog (Drosophila)
chr11_+_98741805 1.10 ENSMUST00000064187.5
Thra
thyroid hormone receptor alpha
chr13_-_21810190 1.08 ENSMUST00000110469.1
ENSMUST00000091749.2
Hist1h2bq
histone cluster 1, H2bq
chr17_-_35164891 1.07 ENSMUST00000025253.5
Prrc2a
proline-rich coiled-coil 2A
chr2_+_91096744 1.06 ENSMUST00000132741.2
Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
chr15_+_85017138 1.06 ENSMUST00000023070.5
Upk3a
uroplakin 3A
chr7_-_102477902 1.04 ENSMUST00000061482.5
Olfr543
olfactory receptor 543
chr9_+_74848437 1.01 ENSMUST00000161862.1
ENSMUST00000162089.1
ENSMUST00000160017.1
ENSMUST00000160950.1
Gm16551
Gm20649
predicted gene 16551
predicted gene 20649
chr6_+_122553799 1.00 ENSMUST00000043301.7
Aicda
activation-induced cytidine deaminase
chr17_-_46556158 0.97 ENSMUST00000015749.5
Srf
serum response factor
chr7_+_27486910 0.96 ENSMUST00000008528.7
Sertad1
SERTA domain containing 1
chr18_+_53551594 0.96 ENSMUST00000115398.1
Prdm6
PR domain containing 6
chr12_-_114060315 0.96 ENSMUST00000103469.2
Ighv14-3
immunoglobulin heavy variable V14-3
chr6_-_65144908 0.95 ENSMUST00000031982.4
Hpgds
hematopoietic prostaglandin D synthase
chr6_+_30568367 0.94 ENSMUST00000049251.5
Cpa4
carboxypeptidase A4
chr13_-_49309217 0.92 ENSMUST00000110087.2
Fgd3
FYVE, RhoGEF and PH domain containing 3
chrX_-_164250368 0.90 ENSMUST00000112263.1
Bmx
BMX non-receptor tyrosine kinase
chr8_+_70234613 0.89 ENSMUST00000145078.1
Sugp2
SURP and G patch domain containing 2
chr14_-_67715585 0.87 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
Cdca2
cell division cycle associated 2
chr11_+_98741871 0.86 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr16_+_17233560 0.86 ENSMUST00000090190.5
ENSMUST00000115698.2
Hic2
hypermethylated in cancer 2
chr1_+_12718496 0.86 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr11_+_60469339 0.84 ENSMUST00000071880.2
ENSMUST00000081823.5
ENSMUST00000094135.2
Myo15
myosin XV
chr17_-_27133902 0.83 ENSMUST00000119227.1
ENSMUST00000025045.8
Uqcc2
ubiquinol-cytochrome c reductase complex assembly factor 2
chr4_-_137118135 0.80 ENSMUST00000154285.1
Gm13001
predicted gene 13001
chr6_-_142804390 0.80 ENSMUST00000111768.1
Gm766
predicted gene 766
chr4_-_88033328 0.79 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr8_+_31150307 0.77 ENSMUST00000098842.2
Tti2
TELO2 interacting protein 2
chr1_-_126830632 0.75 ENSMUST00000112583.1
ENSMUST00000094609.3
Nckap5
NCK-associated protein 5
chr11_+_51289920 0.74 ENSMUST00000102765.2
Col23a1
collagen, type XXIII, alpha 1
chr11_-_5837760 0.73 ENSMUST00000109837.1
Polm
polymerase (DNA directed), mu
chr2_-_71367749 0.71 ENSMUST00000151937.1
Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr8_-_122678653 0.68 ENSMUST00000134045.1
Cbfa2t3
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr6_-_56369625 0.67 ENSMUST00000170774.1
ENSMUST00000168944.1
ENSMUST00000166890.1
Pde1c
phosphodiesterase 1C
chr7_+_141195047 0.67 ENSMUST00000047093.4
Lrrc56
leucine rich repeat containing 56
chr16_-_4880284 0.67 ENSMUST00000037843.6
Ubald1
UBA-like domain containing 1
chr1_+_75236439 0.67 ENSMUST00000082158.6
ENSMUST00000055223.7
Dnajb2
DnaJ (Hsp40) homolog, subfamily B, member 2
chr18_+_50051702 0.66 ENSMUST00000134348.1
ENSMUST00000153873.2
Tnfaip8
tumor necrosis factor, alpha-induced protein 8
chr17_+_47140942 0.66 ENSMUST00000077951.7
Trerf1
transcriptional regulating factor 1
chr7_+_122289297 0.66 ENSMUST00000064989.5
ENSMUST00000064921.4
Prkcb
protein kinase C, beta
chr11_-_98053415 0.66 ENSMUST00000017544.2
Stac2
SH3 and cysteine rich domain 2
chr2_+_74681991 0.65 ENSMUST00000142312.1
Hoxd11
homeobox D11
chr8_-_9771018 0.65 ENSMUST00000110969.3
Fam155a
family with sequence similarity 155, member A
chr19_+_41593363 0.64 ENSMUST00000099454.3
AI606181
expressed sequence AI606181
chr4_+_123183722 0.63 ENSMUST00000152194.1
Hpcal4
hippocalcin-like 4
chr19_+_53140430 0.62 ENSMUST00000111741.2
Add3
adducin 3 (gamma)
chr12_-_115964196 0.61 ENSMUST00000103550.2
Ighv1-83
immunoglobulin heavy variable 1-83
chr17_-_24533709 0.61 ENSMUST00000061764.7
Rab26
RAB26, member RAS oncogene family
chr7_+_82175156 0.58 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3
chr7_-_28372494 0.57 ENSMUST00000119990.1
Plekhg2
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr5_-_122988533 0.57 ENSMUST00000086200.4
ENSMUST00000156474.1
Kdm2b
lysine (K)-specific demethylase 2B
chr17_+_27057288 0.57 ENSMUST00000049308.8
Itpr3
inositol 1,4,5-triphosphate receptor 3
chr14_+_62292475 0.55 ENSMUST00000166879.1
Rnaseh2b
ribonuclease H2, subunit B
chr4_-_64046925 0.55 ENSMUST00000107377.3
Tnc
tenascin C
chr14_+_79515618 0.54 ENSMUST00000110835.1
Elf1
E74-like factor 1
chrX_-_111531163 0.54 ENSMUST00000128819.1
Rps6ka6
ribosomal protein S6 kinase polypeptide 6
chr13_+_21787461 0.53 ENSMUST00000110473.2
ENSMUST00000102982.1
Hist1h2bp
histone cluster 1, H2bp
chr1_+_70725902 0.53 ENSMUST00000161937.1
ENSMUST00000162182.1
Vwc2l
von Willebrand factor C domain-containing protein 2-like
chr4_+_128654686 0.51 ENSMUST00000030588.6
ENSMUST00000136377.1
Phc2
polyhomeotic-like 2 (Drosophila)
chr13_+_83738874 0.51 ENSMUST00000052354.4
C130071C03Rik
RIKEN cDNA C130071C03 gene
chr18_-_80986578 0.50 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr10_+_90071095 0.49 ENSMUST00000183109.1
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr19_-_40994133 0.48 ENSMUST00000117695.1
Blnk
B cell linker
chr12_-_115790884 0.48 ENSMUST00000081809.5
Ighv1-73
immunoglobulin heavy variable 1-73
chr16_-_89818338 0.46 ENSMUST00000164263.2
Tiam1
T cell lymphoma invasion and metastasis 1
chr1_+_70725715 0.46 ENSMUST00000053922.5
Vwc2l
von Willebrand factor C domain-containing protein 2-like
chr5_-_122989086 0.46 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr5_+_53590215 0.46 ENSMUST00000037618.6
Rbpj
recombination signal binding protein for immunoglobulin kappa J region
chr5_-_122900267 0.46 ENSMUST00000031435.7
Kdm2b
lysine (K)-specific demethylase 2B
chrX_+_150594420 0.45 ENSMUST00000112713.2
Pfkfb1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr7_+_27591513 0.44 ENSMUST00000108344.2
Akt2
thymoma viral proto-oncogene 2
chr16_-_91728599 0.42 ENSMUST00000122254.1
Cryzl1
crystallin, zeta (quinone reductase)-like 1
chr13_-_23621090 0.41 ENSMUST00000091704.5
ENSMUST00000051091.3
Hist1h2be
histone cluster 1, H2be
chr4_+_104766308 0.41 ENSMUST00000031663.3
C8b
complement component 8, beta polypeptide
chr9_-_85327110 0.41 ENSMUST00000034802.8
Fam46a
family with sequence similarity 46, member A
chr3_+_76074270 0.40 ENSMUST00000038364.8
Fstl5
follistatin-like 5

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou2f2_Pou3f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.2 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.9 3.5 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.8 3.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.7 2.2 GO:2000041 regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.7 5.6 GO:0002326 B cell lineage commitment(GO:0002326)
0.7 2.1 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.7 2.0 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.6 2.5 GO:0046898 response to cycloheximide(GO:0046898)
0.6 4.6 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.5 2.0 GO:0060775 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.5 3.2 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.4 1.3 GO:1904170 regulation of bleb assembly(GO:1904170)
0.4 4.5 GO:0030916 otic vesicle formation(GO:0030916)
0.4 2.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.4 1.7 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.4 4.4 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.4 44.3 GO:0006334 nucleosome assembly(GO:0006334)
0.3 0.7 GO:1905066 regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901295) regulation of canonical Wnt signaling pathway involved in heart development(GO:1905066)
0.3 3.8 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.3 3.4 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.3 1.0 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.3 3.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.3 0.9 GO:0060686 negative regulation of prostatic bud formation(GO:0060686)
0.3 3.9 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 1.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.3 1.1 GO:0060157 urinary bladder development(GO:0060157)
0.2 1.0 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.2 25.8 GO:0006342 chromatin silencing(GO:0006342)
0.2 1.7 GO:0035799 ureter maturation(GO:0035799)
0.2 2.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.2 1.3 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.2 0.7 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.2 1.5 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.2 1.9 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.2 0.4 GO:0060018 astrocyte fate commitment(GO:0060018)
0.2 2.7 GO:0046085 adenosine metabolic process(GO:0046085)
0.2 7.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.2 1.5 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.2 1.0 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.2 0.5 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.2 1.5 GO:0006265 DNA topological change(GO:0006265)
0.2 2.3 GO:0002043 blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.2 7.7 GO:0006284 base-excision repair(GO:0006284)
0.2 0.3 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.2 3.8 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.2 0.5 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.2 6.2 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 1.9 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.3 GO:0060435 bronchiole development(GO:0060435)
0.1 0.7 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 2.7 GO:0021516 dorsal spinal cord development(GO:0021516)
0.1 1.5 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.2 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 3.7 GO:0031424 keratinization(GO:0031424)
0.1 0.6 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 2.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.1 1.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 1.7 GO:0060736 prostate gland growth(GO:0060736)
0.1 1.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.1 1.6 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 5.5 GO:0001541 ovarian follicle development(GO:0001541)
0.1 0.7 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 1.6 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 1.5 GO:0060575 intestinal epithelial cell differentiation(GO:0060575)
0.1 3.5 GO:0006779 porphyrin-containing compound biosynthetic process(GO:0006779)
0.1 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.7 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.9 GO:0001865 NK T cell differentiation(GO:0001865)
0.1 0.8 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 1.6 GO:0060065 uterus development(GO:0060065)
0.1 0.3 GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.1 0.8 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.2 GO:0071600 otic vesicle morphogenesis(GO:0071600)
0.1 4.6 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.1 1.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.1 0.6 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.1 0.6 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.1 0.3 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 2.5 GO:0060325 face morphogenesis(GO:0060325)
0.1 2.2 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.1 0.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 0.2 GO:0021898 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) cerebral cortex GABAergic interneuron fate commitment(GO:0021893) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898) positive regulation of neural retina development(GO:0061075) positive regulation of retina development in camera-type eye(GO:1902868) positive regulation of amacrine cell differentiation(GO:1902871)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.5 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.1 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.2 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.5 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 1.3 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 1.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0070342 brown fat cell proliferation(GO:0070342) regulation of brown fat cell proliferation(GO:0070347)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0021891 olfactory bulb interneuron differentiation(GO:0021889) olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.5 GO:0050860 negative regulation of antigen receptor-mediated signaling pathway(GO:0050858) negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.6 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 1.6 GO:0065004 protein-DNA complex assembly(GO:0065004)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.4 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 1.4 GO:0051591 response to cAMP(GO:0051591)
0.0 0.7 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.9 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.0 0.1 GO:0009624 response to nematode(GO:0009624)
0.0 0.2 GO:0050857 positive regulation of antigen receptor-mediated signaling pathway(GO:0050857)
0.0 0.4 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 2.4 GO:0035023 regulation of Rho protein signal transduction(GO:0035023)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 0.7 GO:0048286 lung alveolus development(GO:0048286)
0.0 1.5 GO:0007338 single fertilization(GO:0007338)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 7.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.6 47.6 GO:0000786 nucleosome(GO:0000786)
0.4 3.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.4 8.4 GO:0019814 immunoglobulin complex(GO:0019814)
0.3 1.3 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.2 1.5 GO:0001651 dense fibrillar component(GO:0001651)
0.2 2.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.2 1.3 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 1.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 3.7 GO:0001533 cornified envelope(GO:0001533)
0.1 1.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.4 GO:0008623 CHRAC(GO:0008623)
0.1 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 1.9 GO:0070822 Sin3-type complex(GO:0070822)
0.1 1.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.7 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.2 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.1 21.9 GO:0000790 nuclear chromatin(GO:0000790)
0.0 0.4 GO:0042382 paraspeckles(GO:0042382)
0.0 1.0 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.7 GO:0097440 apical dendrite(GO:0097440)
0.0 3.9 GO:0016605 PML body(GO:0016605)
0.0 3.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.5 GO:0031519 PcG protein complex(GO:0031519)
0.0 0.5 GO:0060091 kinocilium(GO:0060091)
0.0 3.6 GO:0005604 basement membrane(GO:0005604)
0.0 1.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.9 GO:0005581 collagen trimer(GO:0005581)
0.0 2.9 GO:0043195 terminal bouton(GO:0043195)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 6.4 GO:0016607 nuclear speck(GO:0016607)
0.0 1.3 GO:0032993 protein-DNA complex(GO:0032993)
0.0 1.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 2.1 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.7 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.5 GO:0005801 cis-Golgi network(GO:0005801)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 7.9 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
1.3 6.7 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.9 3.8 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.8 7.7 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.7 5.6 GO:0070644 vitamin D response element binding(GO:0070644)
0.7 2.0 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.4 2.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.4 1.5 GO:0097100 supercoiled DNA binding(GO:0097100)
0.4 3.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.3 3.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.3 1.9 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.3 2.1 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.3 1.3 GO:0043515 kinetochore binding(GO:0043515)
0.3 3.1 GO:0030274 LIM domain binding(GO:0030274)
0.3 2.5 GO:0051434 BH3 domain binding(GO:0051434)
0.2 6.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.2 1.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 2.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.2 1.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.2 0.7 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.2 0.6 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.2 1.4 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.2 0.6 GO:0019002 GMP binding(GO:0019002)
0.2 0.9 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 1.0 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 2.7 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.6 GO:0005220 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.7 GO:0016918 retinal binding(GO:0016918)
0.1 1.3 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 0.7 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.3 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 5.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 1.5 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.1 4.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 0.7 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 1.1 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.8 GO:0070878 primary miRNA binding(GO:0070878)
0.1 0.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 1.5 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.1 1.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 3.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.5 GO:0045545 syndecan binding(GO:0045545)
0.1 0.5 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 3.2 GO:0045182 translation regulator activity(GO:0045182)
0.1 0.4 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 9.7 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 1.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 2.0 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0051373 FATZ binding(GO:0051373)
0.0 2.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.7 GO:0070628 proteasome binding(GO:0070628)
0.0 0.5 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 1.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 21.6 GO:0046982 protein heterodimerization activity(GO:0046982)
0.0 1.7 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 2.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.0 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0070888 E-box binding(GO:0070888)
0.0 1.5 GO:0005057 receptor signaling protein activity(GO:0005057)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 4.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 2.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 4.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 9.0 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.1 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.2 PID RAS PATHWAY Regulation of Ras family activation
0.1 1.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 1.8 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 1.4 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 4.5 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 2.6 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 1.1 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.9 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 3.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.7 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 43.9 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
1.0 7.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2 6.7 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.2 5.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.2 2.7 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.2 2.5 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 3.3 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 1.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 3.7 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 1.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 4.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.1 3.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 3.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.1 1.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 1.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 3.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.8 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.9 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 1.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 1.9 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events