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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Meis1

Z-value: 1.62

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Transcription factors associated with Meis1

Gene Symbol Gene ID Gene Info
Meis1
ENSMUSG00000020160.12 Meis homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Meis1mm10_v2_chr11_-_19018956_190189730.511.6e-03Click!

Activity profile of Meis1 motif

Sorted Z-values of Meis1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_46404224 9.70 ENSMUST00000107764.2
Hemgn
hemogen
chr4_-_41098174 9.54 ENSMUST00000055327.7
Aqp3
aquaporin 3
chr11_+_58918004 9.05 ENSMUST00000108818.3
ENSMUST00000020792.5
Btnl10
butyrophilin-like 10
chr11_-_69617879 7.43 ENSMUST00000005334.2
Shbg
sex hormone binding globulin
chr14_-_47411666 6.68 ENSMUST00000111778.3
Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr4_-_87806296 6.30 ENSMUST00000126353.1
ENSMUST00000149357.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr9_+_7558429 5.98 ENSMUST00000018765.2
Mmp8
matrix metallopeptidase 8
chr4_-_87806276 5.78 ENSMUST00000148059.1
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr6_+_34412334 5.47 ENSMUST00000007449.8
Akr1b7
aldo-keto reductase family 1, member B7
chr7_+_78913436 4.69 ENSMUST00000121645.1
Isg20
interferon-stimulated protein
chr9_-_107985863 4.64 ENSMUST00000048568.4
Fam212a
family with sequence similarity 212, member A
chr2_-_168767136 4.51 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4
sal-like 4 (Drosophila)
chr7_+_78913401 4.26 ENSMUST00000118867.1
Isg20
interferon-stimulated protein
chr14_-_89898466 4.23 ENSMUST00000081204.4
Gm10110
predicted gene 10110
chrX_-_106840572 4.22 ENSMUST00000062010.9
Zcchc5
zinc finger, CCHC domain containing 5
chr13_+_108316395 4.20 ENSMUST00000171178.1
Depdc1b
DEP domain containing 1B
chr6_+_4747306 4.20 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
Peg10
paternally expressed 10
chr15_+_85510812 3.99 ENSMUST00000079690.2
Gm4825
predicted pseudogene 4825
chr4_-_154042660 3.97 ENSMUST00000047207.6
Ccdc27
coiled-coil domain containing 27
chr10_-_85102487 3.93 ENSMUST00000059383.6
Fhl4
four and a half LIM domains 4
chr5_+_114004781 3.76 ENSMUST00000161610.1
Dao
D-amino acid oxidase
chr6_-_36811361 3.75 ENSMUST00000101534.1
Ptn
pleiotrophin
chr16_+_48872608 3.67 ENSMUST00000065666.4
Retnlg
resistin like gamma
chr2_-_168767029 3.65 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr1_+_136467958 3.64 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr6_-_129876659 3.61 ENSMUST00000014687.4
ENSMUST00000122219.1
Klra17
killer cell lectin-like receptor, subfamily A, member 17
chr3_-_127896271 3.57 ENSMUST00000057198.7
5730508B09Rik
RIKEN cDNA 5730508B09 gene
chr10_+_100015817 3.56 ENSMUST00000130190.1
ENSMUST00000020129.7
Kitl
kit ligand
chr11_-_120648104 3.41 ENSMUST00000026134.2
Myadml2
myeloid-associated differentiation marker-like 2
chr6_+_128399881 3.26 ENSMUST00000120405.1
Nrip2
nuclear receptor interacting protein 2
chr6_+_128399766 3.25 ENSMUST00000001561.5
Nrip2
nuclear receptor interacting protein 2
chr6_-_136941494 3.14 ENSMUST00000111892.1
Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr7_-_143460989 3.10 ENSMUST00000167912.1
ENSMUST00000037287.6
Cdkn1c
cyclin-dependent kinase inhibitor 1C (P57)
chr11_-_109828021 3.02 ENSMUST00000020941.4
1700012B07Rik
RIKEN cDNA 1700012B07 gene
chr7_+_44572370 3.01 ENSMUST00000002274.8
Napsa
napsin A aspartic peptidase
chr1_+_130731963 2.78 ENSMUST00000039323.6
AA986860
expressed sequence AA986860
chr6_-_128891105 2.77 ENSMUST00000178918.1
ENSMUST00000160290.1
BC035044
cDNA sequence BC035044
chr6_+_123172893 2.60 ENSMUST00000088455.5
Clec4b2
C-type lectin domain family 4, member b2
chr13_+_104229366 2.57 ENSMUST00000022227.6
Cenpk
centromere protein K
chr4_-_46566432 2.53 ENSMUST00000030021.7
ENSMUST00000107757.1
Coro2a
coronin, actin binding protein 2A
chr11_+_44617310 2.48 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
Ebf1
early B cell factor 1
chr6_-_133853650 2.48 ENSMUST00000048032.2
Kap
kidney androgen regulated protein
chr15_+_74714832 2.48 ENSMUST00000023265.3
Psca
prostate stem cell antigen
chr2_+_157456917 2.47 ENSMUST00000109529.1
Src
Rous sarcoma oncogene
chr17_-_78906899 2.42 ENSMUST00000042683.6
ENSMUST00000169544.1
Sult6b1
sulfotransferase family, cytosolic, 6B, member 1
chr6_+_145121727 2.39 ENSMUST00000032396.6
Lrmp
lymphoid-restricted membrane protein
chr7_-_115846080 2.38 ENSMUST00000166207.1
Sox6
SRY-box containing gene 6
chr10_+_130322845 2.37 ENSMUST00000042586.8
Tespa1
thymocyte expressed, positive selection associated 1
chr7_+_28863831 2.33 ENSMUST00000138272.1
Lgals7
lectin, galactose binding, soluble 7
chr7_+_27447978 2.31 ENSMUST00000037399.9
ENSMUST00000108358.1
Blvrb
biliverdin reductase B (flavin reductase (NADPH))
chr17_+_56040350 2.29 ENSMUST00000002914.8
Chaf1a
chromatin assembly factor 1, subunit A (p150)
chr14_-_98169542 2.27 ENSMUST00000069334.7
ENSMUST00000071533.6
Dach1
dachshund 1 (Drosophila)
chr5_+_77037045 2.26 ENSMUST00000118941.1
1700023E05Rik
RIKEN cDNA 1700023E05 gene
chr15_-_78572754 2.26 ENSMUST00000043214.6
Rac2
RAS-related C3 botulinum substrate 2
chr7_+_28441026 2.21 ENSMUST00000135686.1
Gmfg
glia maturation factor, gamma
chr17_+_35861318 2.20 ENSMUST00000074259.8
ENSMUST00000174873.1
Nrm
nurim (nuclear envelope membrane protein)
chr2_-_28699661 2.18 ENSMUST00000124840.1
1700026L06Rik
RIKEN cDNA 1700026L06 gene
chr3_+_109123104 2.15 ENSMUST00000029477.6
Slc25a24
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 24
chr7_+_142472080 2.14 ENSMUST00000105966.1
Lsp1
lymphocyte specific 1
chr14_+_54640952 2.13 ENSMUST00000169818.2
Gm17606
predicted gene, 17606
chr2_-_28699636 2.10 ENSMUST00000102877.1
1700026L06Rik
RIKEN cDNA 1700026L06 gene
chr3_+_116594959 2.09 ENSMUST00000029571.8
Sass6
spindle assembly 6 homolog (C. elegans)
chr7_+_28440927 2.07 ENSMUST00000078845.6
Gmfg
glia maturation factor, gamma
chr16_-_57071346 2.05 ENSMUST00000067173.6
2310005G13Rik
RIKEN cDNA 2310005G13 gene
chr9_-_26806384 2.04 ENSMUST00000162702.1
ENSMUST00000040398.7
ENSMUST00000066560.6
Glb1l2
galactosidase, beta 1-like 2
chr1_+_43445736 2.03 ENSMUST00000086421.5
ENSMUST00000114744.1
Nck2
non-catalytic region of tyrosine kinase adaptor protein 2
chr12_-_50649190 2.01 ENSMUST00000002765.7
Prkd1
protein kinase D1
chr13_+_49544443 1.95 ENSMUST00000177948.1
ENSMUST00000021820.6
Aspn
asporin
chr7_+_142471838 1.93 ENSMUST00000038946.2
Lsp1
lymphocyte specific 1
chr11_+_117986292 1.92 ENSMUST00000132676.1
Pgs1
phosphatidylglycerophosphate synthase 1
chr12_-_103407820 1.84 ENSMUST00000056140.4
9330161L09Rik
RIKEN cDNA 9330161L09 gene
chr2_-_165388245 1.82 ENSMUST00000103084.3
Zfp334
zinc finger protein 334
chr4_+_19818722 1.82 ENSMUST00000035890.7
Slc7a13
solute carrier family 7, (cationic amino acid transporter, y+ system) member 13
chr8_+_70501116 1.79 ENSMUST00000127983.1
Crlf1
cytokine receptor-like factor 1
chr15_-_26895049 1.74 ENSMUST00000059204.9
Fbxl7
F-box and leucine-rich repeat protein 7
chr17_-_23844155 1.69 ENSMUST00000122936.1
ENSMUST00000024926.7
ENSMUST00000151797.1
Prss41
protease, serine, 41
chr11_-_34783850 1.67 ENSMUST00000093193.5
ENSMUST00000101365.2
Dock2
dedicator of cyto-kinesis 2
chr3_-_87263518 1.66 ENSMUST00000090986.4
Fcrls
Fc receptor-like S, scavenger receptor
chr9_+_64281575 1.66 ENSMUST00000034964.6
Tipin
timeless interacting protein
chr17_-_71475285 1.66 ENSMUST00000127430.1
Smchd1
SMC hinge domain containing 1
chr17_-_40935047 1.65 ENSMUST00000087114.3
Cenpq
centromere protein Q
chr16_-_50732707 1.64 ENSMUST00000169791.2
5330426P16Rik
RIKEN cDNA 5330426P16 gene
chr7_-_83735503 1.64 ENSMUST00000001792.4
Il16
interleukin 16
chr15_+_61985540 1.64 ENSMUST00000159327.1
ENSMUST00000167731.1
Myc
myelocytomatosis oncogene
chr3_-_113258837 1.63 ENSMUST00000098673.3
Amy2a5
amylase 2a5
chr11_-_109472611 1.63 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr11_-_109828036 1.61 ENSMUST00000106674.1
1700012B07Rik
RIKEN cDNA 1700012B07 gene
chr11_+_101316917 1.61 ENSMUST00000151385.1
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr7_+_45434833 1.60 ENSMUST00000003964.8
Gys1
glycogen synthase 1, muscle
chr6_+_8520008 1.59 ENSMUST00000162567.1
ENSMUST00000161217.1
Glcci1
glucocorticoid induced transcript 1
chr3_+_127553462 1.59 ENSMUST00000043108.4
4930422G04Rik
RIKEN cDNA 4930422G04 gene
chr7_+_45434876 1.58 ENSMUST00000107766.1
Gys1
glycogen synthase 1, muscle
chr12_+_76837408 1.57 ENSMUST00000041008.9
Fntb
farnesyltransferase, CAAX box, beta
chr6_-_67376147 1.55 ENSMUST00000018485.3
Il12rb2
interleukin 12 receptor, beta 2
chr3_-_87263703 1.53 ENSMUST00000146512.1
Fcrls
Fc receptor-like S, scavenger receptor
chr5_+_67607873 1.53 ENSMUST00000087241.5
Shisa3
shisa homolog 3 (Xenopus laevis)
chr5_+_143909964 1.53 ENSMUST00000148011.1
ENSMUST00000110709.3
Pms2
postmeiotic segregation increased 2 (S. cerevisiae)
chr11_+_80858358 1.48 ENSMUST00000103223.1
ENSMUST00000103222.3
Spaca3
sperm acrosome associated 3
chr19_-_37207293 1.46 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chrX_-_164076482 1.44 ENSMUST00000134272.1
Siah1b
seven in absentia 1B
chr2_+_26319741 1.40 ENSMUST00000066889.6
Gpsm1
G-protein signalling modulator 1 (AGS3-like, C. elegans)
chr10_+_41810528 1.37 ENSMUST00000099931.3
Sesn1
sestrin 1
chr11_+_101442298 1.36 ENSMUST00000077856.6
Rpl27
ribosomal protein L27
chr2_+_43748802 1.36 ENSMUST00000112824.1
ENSMUST00000055776.7
Arhgap15
Rho GTPase activating protein 15
chr8_-_70766654 1.35 ENSMUST00000034299.5
Ifi30
interferon gamma inducible protein 30
chr15_+_59374198 1.34 ENSMUST00000079703.3
ENSMUST00000168722.1
Nsmce2
non-SMC element 2 homolog (MMS21, S. cerevisiae)
chr2_-_36136602 1.32 ENSMUST00000122456.1
Rbm18
RNA binding motif protein 18
chr7_-_34168516 1.31 ENSMUST00000102746.4
Uba2
ubiquitin-like modifier activating enzyme 2
chr4_+_44943727 1.30 ENSMUST00000154177.1
Gm12678
predicted gene 12678
chr6_-_67339661 1.30 ENSMUST00000117441.1
Il12rb2
interleukin 12 receptor, beta 2
chr10_+_122678764 1.28 ENSMUST00000161487.1
ENSMUST00000067918.5
Ppm1h
protein phosphatase 1H (PP2C domain containing)
chr17_+_34398802 1.26 ENSMUST00000114175.1
ENSMUST00000078615.5
ENSMUST00000139063.1
ENSMUST00000097348.2
BC051142
cDNA sequence BC051142
chr9_+_87022014 1.26 ENSMUST00000168529.2
ENSMUST00000174724.1
ENSMUST00000173126.1
Cyb5r4
cytochrome b5 reductase 4
chr4_-_43578636 1.21 ENSMUST00000130443.1
Gba2
glucosidase beta 2
chr14_+_31019183 1.21 ENSMUST00000052239.5
Pbrm1
polybromo 1
chr11_+_101316200 1.20 ENSMUST00000142640.1
ENSMUST00000019470.7
Psme3
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr14_+_103513328 1.19 ENSMUST00000095576.3
Scel
sciellin
chr4_-_156059414 1.19 ENSMUST00000184348.1
Ttll10
tubulin tyrosine ligase-like family, member 10
chr18_+_44104407 1.18 ENSMUST00000081271.5
Spink12
serine peptidase inhibitor, Kazal type 11
chr8_+_94214567 1.16 ENSMUST00000079961.6
Nup93
nucleoporin 93
chrX_+_155262443 1.15 ENSMUST00000026324.9
Acot9
acyl-CoA thioesterase 9
chr7_+_70388305 1.15 ENSMUST00000080024.5
B130024G19Rik
RIKEN cDNA B130024G19 gene
chr15_-_36608959 1.14 ENSMUST00000001809.8
Pabpc1
poly(A) binding protein, cytoplasmic 1
chr19_+_23619742 1.13 ENSMUST00000104916.2
Gm9493
predicted gene 9493
chr2_+_181319806 1.12 ENSMUST00000153112.1
Rtel1
regulator of telomere elongation helicase 1
chr4_-_43578824 1.12 ENSMUST00000030189.7
Gba2
glucosidase beta 2
chrX_-_59134421 1.11 ENSMUST00000033473.5
Fgf13
fibroblast growth factor 13
chr4_+_150914562 1.11 ENSMUST00000135169.1
Tnfrsf9
tumor necrosis factor receptor superfamily, member 9
chr11_-_83462961 1.10 ENSMUST00000021020.6
ENSMUST00000119346.1
ENSMUST00000103209.3
ENSMUST00000108137.2
Mmp28
matrix metallopeptidase 28 (epilysin)
chr5_+_136057267 1.10 ENSMUST00000006303.4
ENSMUST00000156530.1
Upk3bl
uroplakin 3B-like
chr9_-_112217261 1.10 ENSMUST00000159451.1
ENSMUST00000162796.1
ENSMUST00000161097.1
Arpp21
cyclic AMP-regulated phosphoprotein, 21
chr16_-_88774201 1.08 ENSMUST00000054223.2
2310057N15Rik
RIKEN cDNA 2310057N15 gene
chr3_-_101307079 1.07 ENSMUST00000097146.2
Gm10355
predicted gene 10355
chr5_-_104114088 1.06 ENSMUST00000031249.3
Sparcl1
SPARC-like 1
chr12_-_69892989 1.06 ENSMUST00000110567.1
ENSMUST00000171211.1
Map4k5
mitogen-activated protein kinase kinase kinase kinase 5
chr2_+_181319714 1.06 ENSMUST00000098971.4
ENSMUST00000054622.8
ENSMUST00000108814.1
ENSMUST00000048608.9
ENSMUST00000108815.1
Rtel1
regulator of telomere elongation helicase 1
chr8_+_33731867 1.05 ENSMUST00000170705.1
Gtf2e2
general transcription factor II E, polypeptide 2 (beta subunit)
chr1_-_173227229 1.05 ENSMUST00000049706.5
Fcer1a
Fc receptor, IgE, high affinity I, alpha polypeptide
chr4_+_101507947 1.05 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr9_-_95845215 1.04 ENSMUST00000093800.2
Pls1
plastin 1 (I-isoform)
chr1_+_132880273 1.03 ENSMUST00000027706.3
Lrrn2
leucine rich repeat protein 2, neuronal
chr4_-_132261521 1.03 ENSMUST00000105965.1
Gmeb1
glucocorticoid modulatory element binding protein 1
chr15_-_36555556 1.01 ENSMUST00000161202.1
ENSMUST00000013755.5
Snx31
sorting nexin 31
chr9_+_44134562 0.97 ENSMUST00000034650.8
ENSMUST00000098852.2
Mcam
melanoma cell adhesion molecule
chr4_-_152038568 0.96 ENSMUST00000030792.1
Tas1r1
taste receptor, type 1, member 1
chr5_+_115011111 0.95 ENSMUST00000031530.5
Sppl3
signal peptide peptidase 3
chr12_+_84996309 0.93 ENSMUST00000168977.1
ENSMUST00000021670.8
Ylpm1
YLP motif containing 1
chrX_+_112011007 0.92 ENSMUST00000131304.1
Tex16
testis expressed gene 16
chr15_+_100038635 0.92 ENSMUST00000100203.3
Dip2b
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr4_-_151044564 0.90 ENSMUST00000103204.4
Per3
period circadian clock 3
chr10_+_70868633 0.90 ENSMUST00000058942.5
4930533K18Rik
RIKEN cDNA 4930533K18 gene
chr17_-_6477102 0.89 ENSMUST00000167717.2
Tmem181b-ps
transmembrane protein 181B, pseudogene
chr7_+_25228687 0.88 ENSMUST00000169914.1
9130221H12Rik
RIKEN cDNA 9130221H12 gene
chr8_+_33732049 0.88 ENSMUST00000167264.1
Gtf2e2
general transcription factor II E, polypeptide 2 (beta subunit)
chr2_-_120731503 0.85 ENSMUST00000110701.1
ENSMUST00000110700.1
Cdan1
congenital dyserythropoietic anemia, type I (human)
chr3_-_146839365 0.85 ENSMUST00000084614.3
Gm10288
predicted gene 10288
chr7_-_45434590 0.85 ENSMUST00000107771.3
ENSMUST00000141761.1
Ruvbl2
RuvB-like protein 2
chr9_+_120539801 0.84 ENSMUST00000047687.7
Entpd3
ectonucleoside triphosphate diphosphohydrolase 3
chr10_-_14544972 0.83 ENSMUST00000041168.4
Gpr126
G protein-coupled receptor 126
chr10_+_82699007 0.82 ENSMUST00000020478.7
Hcfc2
host cell factor C2
chr5_-_100820929 0.82 ENSMUST00000117364.1
ENSMUST00000055245.6
Fam175a
family with sequence similarity 175, member A
chr10_-_76442758 0.81 ENSMUST00000001179.5
Pcnt
pericentrin (kendrin)
chr17_-_36889533 0.81 ENSMUST00000172711.1
Trim40
tripartite motif-containing 40
chr12_+_91400990 0.79 ENSMUST00000021346.7
ENSMUST00000021343.6
Tshr
thyroid stimulating hormone receptor
chr1_+_118321834 0.79 ENSMUST00000027626.6
ENSMUST00000112688.3
Mki67ip
Mki67 (FHA domain) interacting nucleolar phosphoprotein
chr11_+_53567361 0.79 ENSMUST00000057330.8
ENSMUST00000120613.2
ENSMUST00000173744.1
ENSMUST00000118353.2
Kif3a
kinesin family member 3A
chr2_-_165852149 0.79 ENSMUST00000109258.3
Zmynd8
zinc finger, MYND-type containing 8
chr4_+_132535542 0.79 ENSMUST00000094657.3
ENSMUST00000105940.3
ENSMUST00000105939.3
ENSMUST00000150207.1
Dnajc8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr12_+_99964499 0.77 ENSMUST00000177549.1
ENSMUST00000160413.1
ENSMUST00000162221.1
ENSMUST00000049788.8
Kcnk13
potassium channel, subfamily K, member 13
chr3_-_10208569 0.76 ENSMUST00000029041.4
Fabp4
fatty acid binding protein 4, adipocyte
chr10_+_85102627 0.76 ENSMUST00000095383.4
AI597468
expressed sequence AI597468
chr4_-_132261596 0.75 ENSMUST00000105964.1
Gmeb1
glucocorticoid modulatory element binding protein 1
chr12_-_69893162 0.74 ENSMUST00000049239.7
ENSMUST00000110570.1
Map4k5
mitogen-activated protein kinase kinase kinase kinase 5
chr13_-_59556845 0.74 ENSMUST00000170378.1
ENSMUST00000169434.1
Agtpbp1
ATP/GTP binding protein 1
chr5_+_37185897 0.73 ENSMUST00000094840.3
Gm1043
predicted gene 1043
chr1_-_93343482 0.73 ENSMUST00000128253.1
Pask
PAS domain containing serine/threonine kinase
chr11_+_115564434 0.71 ENSMUST00000021085.4
Nup85
nucleoporin 85
chrX_+_68761839 0.68 ENSMUST00000069731.5
Fmr1nb
fragile X mental retardation 1 neighbor
chr11_+_101442440 0.67 ENSMUST00000107249.1
Rpl27
ribosomal protein L27
chrY_+_90755657 0.63 ENSMUST00000167967.2
Gm21857
predicted gene, 21857
chr11_-_58801944 0.63 ENSMUST00000094156.4
ENSMUST00000060581.3
Fam183b
family with sequence similarity 183, member B
chrX_+_68761875 0.62 ENSMUST00000114647.1
Fmr1nb
fragile X mental retardation 1 neighbor
chr8_+_84856982 0.62 ENSMUST00000003906.6
ENSMUST00000109754.1
Farsa
phenylalanyl-tRNA synthetase, alpha subunit
chrX_+_68761890 0.62 ENSMUST00000071848.6
Fmr1nb
fragile X mental retardation 1 neighbor
chr11_-_70969953 0.61 ENSMUST00000108530.1
ENSMUST00000035283.4
ENSMUST00000108531.1
Nup88
nucleoporin 88
chr12_-_108702265 0.60 ENSMUST00000167978.1
ENSMUST00000021691.4
Degs2
degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase
chr3_+_53845086 0.59 ENSMUST00000108014.1
Gm10985
predicted gene 10985
chr14_+_25459267 0.59 ENSMUST00000007961.8
Zmiz1
zinc finger, MIZ-type containing 1
chr5_+_150673739 0.58 ENSMUST00000016569.4
ENSMUST00000038900.8
Pds5b
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr7_+_27862557 0.58 ENSMUST00000053722.8
Zfp607
zinc finger proten 607
chr17_-_44736648 0.57 ENSMUST00000113572.2
Runx2
runt related transcription factor 2
chr15_-_34678694 0.56 ENSMUST00000040791.7
Nipal2
NIPA-like domain containing 2
chr8_-_125492710 0.55 ENSMUST00000108775.1
Sipa1l2
signal-induced proliferation-associated 1 like 2
chr9_-_107606656 0.55 ENSMUST00000073448.5
Sema3b
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr1_+_134405984 0.55 ENSMUST00000173908.1
Cyb5r1
cytochrome b5 reductase 1
chr11_+_32455362 0.55 ENSMUST00000051053.4
Ubtd2
ubiquitin domain containing 2
chr7_-_3825641 0.55 ENSMUST00000094911.4
ENSMUST00000108619.1
ENSMUST00000108620.1
Gm15448
predicted gene 15448
chr16_+_88777829 0.54 ENSMUST00000009191.3
Gm5965
predicted gene 5965
chr12_-_114406773 0.54 ENSMUST00000177949.1
Ighv6-4
immunoglobulin heavy variable V6-4
chr8_+_105880875 0.53 ENSMUST00000040254.9
ENSMUST00000119261.1
Edc4
enhancer of mRNA decapping 4

Network of associatons between targets according to the STRING database.

First level regulatory network of Meis1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.5 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
1.8 9.0 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
1.4 4.3 GO:0071846 actin filament debranching(GO:0071846)
1.3 3.8 GO:0055130 D-serine catabolic process(GO:0036088) D-alanine family amino acid metabolic process(GO:0046144) D-alanine metabolic process(GO:0046436) D-alanine catabolic process(GO:0055130)
1.2 3.6 GO:0033624 negative regulation of integrin activation(GO:0033624)
0.9 3.8 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.9 3.7 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.8 2.4 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.8 12.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.6 3.6 GO:0070668 negative regulation of mast cell apoptotic process(GO:0033026) mast cell proliferation(GO:0070662) regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.6 1.7 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.6 1.7 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.5 2.2 GO:1904430 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
0.5 2.5 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.5 1.5 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.5 2.3 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.5 2.3 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.4 1.3 GO:0034184 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.4 8.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.4 1.6 GO:0090095 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.4 1.6 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.4 3.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.4 2.0 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.4 3.1 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.4 1.5 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.4 2.3 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.4 2.2 GO:0015867 ATP transport(GO:0015867)
0.3 1.5 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.3 2.3 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.3 2.0 GO:0089700 protein kinase D signaling(GO:0089700)
0.3 1.7 GO:0048478 replication fork protection(GO:0048478)
0.3 1.1 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.3 0.8 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.3 1.0 GO:0045399 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
0.3 1.0 GO:1902896 terminal web assembly(GO:1902896)
0.3 1.8 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 1.9 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.2 6.0 GO:0030574 collagen catabolic process(GO:0030574)
0.2 1.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.2 3.0 GO:0043129 surfactant homeostasis(GO:0043129)
0.2 1.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.2 1.4 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.2 1.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.2 2.4 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 0.9 GO:0071899 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.2 0.4 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.2 2.6 GO:0002579 positive regulation of antigen processing and presentation(GO:0002579)
0.2 0.6 GO:0006667 sphinganine metabolic process(GO:0006667)
0.2 1.2 GO:0018094 protein polyglycylation(GO:0018094)
0.2 1.0 GO:0050917 sensory perception of umami taste(GO:0050917)
0.2 1.0 GO:0072318 clathrin coat disassembly(GO:0072318)
0.2 1.1 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 0.8 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.2 0.6 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.4 GO:2000642 intralumenal vesicle formation(GO:0070676) negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.8 GO:1904587 response to glycoprotein(GO:1904587)
0.1 0.9 GO:0007296 vitellogenesis(GO:0007296)
0.1 1.6 GO:0050930 induction of positive chemotaxis(GO:0050930)
0.1 1.0 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.1 1.5 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.4 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 1.0 GO:0045945 positive regulation of transcription from RNA polymerase III promoter(GO:0045945)
0.1 0.6 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 2.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.8 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 0.5 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.7 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.1 0.8 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.1 0.5 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 2.1 GO:0007099 centriole replication(GO:0007099)
0.1 0.8 GO:1990403 embryonic brain development(GO:1990403)
0.1 3.2 GO:0009250 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.8 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 8.6 GO:0045667 regulation of osteoblast differentiation(GO:0045667)
0.0 0.2 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.0 2.2 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.4 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.3 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.5 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.2 GO:0014738 regulation of muscle hyperplasia(GO:0014738) positive regulation of muscle adaptation(GO:0014744) muscle hyperplasia(GO:0014900)
0.0 0.2 GO:0018343 protein farnesylation(GO:0018343)
0.0 3.2 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.3 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 1.0 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.2 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 1.7 GO:0051310 metaphase plate congression(GO:0051310)
0.0 0.1 GO:0060126 somatotropin secreting cell differentiation(GO:0060126)
0.0 1.3 GO:0042168 heme metabolic process(GO:0042168)
0.0 4.2 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.0 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.2 GO:0009405 pathogenesis(GO:0009405)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 2.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.9 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 1.1 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.2 GO:0046878 angiotensin-mediated drinking behavior(GO:0003051) tachykinin receptor signaling pathway(GO:0007217) positive regulation of synaptic transmission, cholinergic(GO:0032224) operant conditioning(GO:0035106) positive regulation of saliva secretion(GO:0046878)
0.0 0.8 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 2.5 GO:0070373 negative regulation of ERK1 and ERK2 cascade(GO:0070373)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.0 GO:0021767 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373)
0.0 0.2 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 1.4 GO:0042149 cellular response to glucose starvation(GO:0042149)
0.0 0.6 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 1.9 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 2.8 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.4 GO:2000637 positive regulation of gene silencing by miRNA(GO:2000637)
0.0 4.2 GO:0007219 Notch signaling pathway(GO:0007219)
0.0 0.0 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.1 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 4.3 GO:0021915 neural tube development(GO:0021915)
0.0 0.3 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.9 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 1.1 GO:0042274 ribosomal small subunit biogenesis(GO:0042274)
0.0 5.7 GO:0022412 cellular process involved in reproduction in multicellular organism(GO:0022412)
0.0 2.0 GO:0006364 rRNA processing(GO:0006364)
0.0 1.1 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 0.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) response to ionomycin(GO:1904636) cellular response to ionomycin(GO:1904637)
0.0 0.1 GO:0072093 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.0 1.3 GO:0007338 single fertilization(GO:0007338)
0.0 0.7 GO:0032204 regulation of telomere maintenance(GO:0032204)
0.0 0.7 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.5 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.2 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.3 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.8 GO:1903955 positive regulation of protein targeting to mitochondrion(GO:1903955)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0033186 CAF-1 complex(GO:0033186)
0.7 2.8 GO:0008537 proteasome activator complex(GO:0008537)
0.6 1.9 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.4 1.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.4 1.3 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.3 2.1 GO:0098536 deuterosome(GO:0098536)
0.3 6.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 0.9 GO:0071007 U2-type catalytic step 2 spliceosome(GO:0071007)
0.3 1.5 GO:0032389 MutLalpha complex(GO:0032389)
0.3 0.8 GO:0016939 kinesin II complex(GO:0016939)
0.3 3.0 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 1.7 GO:0031298 replication fork protection complex(GO:0031298)
0.2 1.7 GO:0001740 Barr body(GO:0001740)
0.2 12.0 GO:0008023 transcription elongation factor complex(GO:0008023)
0.2 0.6 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.2 9.5 GO:0015030 Cajal body(GO:0015030)
0.2 1.3 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.2 1.0 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 2.2 GO:0005652 nuclear lamina(GO:0005652)
0.1 1.0 GO:1990357 terminal web(GO:1990357)
0.1 1.1 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.9 GO:0097255 R2TP complex(GO:0097255)
0.1 3.6 GO:0051233 spindle midzone(GO:0051233)
0.1 1.4 GO:0061700 GATOR2 complex(GO:0061700)
0.1 2.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.3 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.1 0.2 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 8.3 GO:0000792 heterochromatin(GO:0000792)
0.1 0.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 2.5 GO:0002102 podosome(GO:0002102)
0.1 0.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0000243 commitment complex(GO:0000243)
0.0 1.5 GO:0090544 BAF-type complex(GO:0090544)
0.0 1.0 GO:0000421 autophagosome membrane(GO:0000421)
0.0 1.6 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.8 GO:0000242 pericentriolar material(GO:0000242)
0.0 3.9 GO:0030175 filopodium(GO:0030175)
0.0 1.1 GO:0032040 small-subunit processome(GO:0032040)
0.0 3.7 GO:0016234 inclusion body(GO:0016234)
0.0 0.4 GO:0032009 early phagosome(GO:0032009)
0.0 0.5 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 3.8 GO:0005604 basement membrane(GO:0005604)
0.0 9.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 1.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.7 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.8 GO:0005643 nuclear pore(GO:0005643)
0.0 2.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 5.5 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 2.1 GO:0030027 lamellipodium(GO:0030027)
0.0 4.2 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.5 GO:0043195 terminal bouton(GO:0043195)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.0 1.9 GO:0000775 chromosome, centromeric region(GO:0000775)
0.0 0.8 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.5 GO:0000781 chromosome, telomeric region(GO:0000781)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 9.0 GO:0008859 exoribonuclease II activity(GO:0008859)
1.9 9.5 GO:0015254 glycerol channel activity(GO:0015254)
1.3 3.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
1.1 3.2 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.9 3.8 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.8 2.3 GO:0004348 glucosylceramidase activity(GO:0004348)
0.6 5.5 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.6 3.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.6 2.3 GO:0004074 biliverdin reductase activity(GO:0004074)
0.4 1.2 GO:0070737 protein-glycine ligase activity, elongating(GO:0070737)
0.4 3.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 1.5 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.3 2.0 GO:0004565 beta-galactosidase activity(GO:0004565)
0.3 4.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.3 8.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.3 2.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.3 2.3 GO:0070087 chromo shadow domain binding(GO:0070087)
0.3 2.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 1.0 GO:0019767 IgE receptor activity(GO:0019767)
0.2 2.5 GO:0071253 connexin binding(GO:0071253)
0.2 1.9 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.2 1.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.2 1.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.2 1.4 GO:0070728 leucine binding(GO:0070728)
0.2 1.8 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 3.6 GO:0042288 MHC class I protein binding(GO:0042288)
0.2 1.8 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.2 2.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 4.6 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.1 1.6 GO:0042609 CD4 receptor binding(GO:0042609)
0.1 0.6 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.9 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.4 GO:0051431 corticotropin-releasing hormone receptor 2 binding(GO:0051431)
0.1 1.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.4 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.6 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 2.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 1.2 GO:0008527 taste receptor activity(GO:0008527)
0.1 1.7 GO:0042608 T cell receptor binding(GO:0042608)
0.1 3.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.5 GO:0003796 lysozyme activity(GO:0003796)
0.1 1.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 1.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.1 1.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 2.5 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.1 2.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 0.3 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 7.1 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.2 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.4 GO:0033592 RNA strand annealing activity(GO:0033592)
0.1 0.9 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 1.1 GO:0008266 poly(A) binding(GO:0008143) poly(U) RNA binding(GO:0008266)
0.0 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.8 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.2 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 6.3 GO:0005496 steroid binding(GO:0005496)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.8 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 1.2 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 0.2 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 6.7 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 1.8 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 1.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.6 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 2.2 GO:0005518 collagen binding(GO:0005518)
0.0 2.9 GO:0005179 hormone activity(GO:0005179)
0.0 1.6 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.5 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.4 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 1.1 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 3.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 1.8 GO:0015297 antiporter activity(GO:0015297)
0.0 0.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.0 0.1 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.0 GO:0001962 alpha-1,3-galactosyltransferase activity(GO:0001962)
0.0 1.7 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.8 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 2.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.9 GO:0003777 microtubule motor activity(GO:0003777)
0.0 2.9 GO:0051015 actin filament binding(GO:0051015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 6.7 PID AURORA A PATHWAY Aurora A signaling
0.2 7.4 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 8.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.1 3.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 3.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 10.7 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 2.7 PID IL27 PATHWAY IL27-mediated signaling events
0.1 2.0 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 2.0 ST GA13 PATHWAY G alpha 13 Pathway
0.0 1.7 PID ATR PATHWAY ATR signaling pathway
0.0 4.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 1.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID ARF6 PATHWAY Arf6 signaling events
0.0 6.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID ATM PATHWAY ATM pathway
0.0 1.0 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.8 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.3 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.8 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.2 PID EPO PATHWAY EPO signaling pathway
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.5 PID FGF PATHWAY FGF signaling pathway
0.0 0.9 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 9.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 6.0 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.2 2.7 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 9.0 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 2.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 2.9 REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.1 4.2 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 2.0 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.1 0.8 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 2.3 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 2.6 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 1.0 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.0 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.6 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.9 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 6.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 2.9 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.5 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.9 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 1.0 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.6 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.8 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 2.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 1.3 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis