Project

avrg: GSE58827: Dynamics of the Mouse Liver

Navigation
Downloads

Results for Lhx5_Lmx1b_Lhx1

Z-value: 1.02

Motif logo

Transcription factors associated with Lhx5_Lmx1b_Lhx1

Gene Symbol Gene ID Gene Info
ENSMUSG00000029595.7 LIM homeobox protein 5
ENSMUSG00000038765.7 LIM homeobox transcription factor 1 beta
ENSMUSG00000018698.9 LIM homeobox protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Lmx1bmm10_v2_chr2_-_33640480_336405110.401.5e-02Click!
Lhx1mm10_v2_chr11_-_84525514_845255420.317.0e-02Click!
Lhx5mm10_v2_chr5_+_120431770_1204319050.115.4e-01Click!

Activity profile of Lhx5_Lmx1b_Lhx1 motif

Sorted Z-values of Lhx5_Lmx1b_Lhx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_41377604 10.05 ENSMUST00000096003.5
protease, serine, 3
chr6_-_41446062 8.44 ENSMUST00000095999.5
predicted gene 10334
chr17_-_48432723 4.20 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr14_+_80000292 3.71 ENSMUST00000088735.3
olfactomedin 4
chr2_-_160619971 3.50 ENSMUST00000109473.1
predicted gene 14221
chr6_+_41354105 3.16 ENSMUST00000072103.5
trypsin 10
chr7_-_142656018 3.08 ENSMUST00000178921.1
insulin-like growth factor 2
chr4_+_145585166 3.04 ENSMUST00000105739.1
ENSMUST00000119718.1
predicted gene 13212
chr7_-_142699510 3.03 ENSMUST00000105934.1
insulin II
chr10_+_75566257 2.81 ENSMUST00000129232.1
ENSMUST00000143792.1
gamma-glutamyltransferase 1
chr3_-_20275659 2.80 ENSMUST00000011607.5
carboxypeptidase B1 (tissue)
chr11_+_67798269 2.59 ENSMUST00000168612.1
ENSMUST00000040574.4
dehydrogenase/reductase (SDR family) member 7C
chr17_-_28560704 2.49 ENSMUST00000114785.1
ENSMUST00000025062.3
colipase, pancreatic
chr10_+_37139558 2.41 ENSMUST00000062667.3
RIKEN cDNA 5930403N24 gene
chr6_+_123262107 2.38 ENSMUST00000032240.2
C-type lectin domain family 4, member d
chr19_-_39886730 1.86 ENSMUST00000168838.1
cytochrome P450, family 2, subfamily c, polypeptide 69
chr13_+_46502113 1.85 ENSMUST00000119341.1
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr11_+_87793470 1.70 ENSMUST00000020779.4
myeloperoxidase
chr4_+_148901128 1.70 ENSMUST00000147270.1
castor zinc finger 1
chr7_+_66365905 1.65 ENSMUST00000107486.1
predicted gene 10974
chr11_-_11970540 1.47 ENSMUST00000109653.1
growth factor receptor bound protein 10
chr11_-_87359011 1.45 ENSMUST00000055438.4
protein phosphatase 1E (PP2C domain containing)
chr3_-_17230976 1.43 ENSMUST00000177874.1
predicted gene 5283
chr6_+_6248659 1.36 ENSMUST00000181633.1
ENSMUST00000176283.1
ENSMUST00000175814.1
ENSMUST00000181192.1
predicted gene 20619
chr4_+_34893772 1.31 ENSMUST00000029975.3
ENSMUST00000135871.1
ENSMUST00000108130.1
glycoprotein hormones, alpha subunit
chr19_-_34166037 1.30 ENSMUST00000025686.7
ankyrin repeat domain 22
chrX_+_101449078 1.18 ENSMUST00000033674.5
integrin beta 1 binding protein 2
chr13_-_105271039 1.12 ENSMUST00000069686.6
ring finger protein 180
chr9_+_100597686 1.12 ENSMUST00000124487.1
stromal antigen 1
chr13_-_102906046 1.03 ENSMUST00000171791.1
microtubule associated serine/threonine kinase family member 4
chr4_+_147553277 1.02 ENSMUST00000139784.1
ENSMUST00000143885.1
ENSMUST00000081742.6
predicted gene 13154
chr2_-_72813665 1.02 ENSMUST00000136807.1
ENSMUST00000148327.1
RIKEN cDNA 6430710C18 gene
chr14_+_27000362 0.99 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr8_-_41215146 0.98 ENSMUST00000034003.4
fibrinogen-like protein 1
chr2_-_165368723 0.93 ENSMUST00000141140.1
ENSMUST00000103085.1
zinc finger protein 663
chr4_+_115057683 0.93 ENSMUST00000161601.1
T cell acute lymphocytic leukemia 1
chr16_+_48872608 0.92 ENSMUST00000065666.4
resistin like gamma
chr13_+_19342154 0.92 ENSMUST00000103566.3
T cell receptor gamma, constant 4
chr9_+_119063429 0.92 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
villin-like
chr5_+_13398688 0.90 ENSMUST00000125629.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chrX_+_157699113 0.90 ENSMUST00000112521.1
small muscle protein, X-linked
chr9_-_49798905 0.89 ENSMUST00000114476.2
neural cell adhesion molecule 1
chr11_+_67200052 0.87 ENSMUST00000124516.1
ENSMUST00000018637.8
myosin, heavy polypeptide 1, skeletal muscle, adult
chr5_-_43981757 0.86 ENSMUST00000061299.7
fibroblast growth factor binding protein 1
chr4_+_136172367 0.80 ENSMUST00000061721.5
E2F transcription factor 2
chr1_+_170308802 0.77 ENSMUST00000056991.5
RIKEN cDNA 1700015E13 gene
chr4_+_147492417 0.76 ENSMUST00000105721.2
predicted gene 13152
chr2_+_173153048 0.74 ENSMUST00000029017.5
phosphoenolpyruvate carboxykinase 1, cytosolic
chr1_-_172027269 0.74 ENSMUST00000027837.6
ENSMUST00000111264.1
vang-like 2 (van gogh, Drosophila)
chr1_-_133661318 0.72 ENSMUST00000179598.1
ENSMUST00000027736.6
zinc finger, BED domain containing 6
zinc finger CCCH type containing 11A
chr5_-_108795352 0.72 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chr8_+_34054622 0.72 ENSMUST00000149618.1
predicted gene 9951
chr15_+_98571004 0.71 ENSMUST00000023728.6
RIKEN cDNA 4930415O20 gene
chr8_+_121116163 0.67 ENSMUST00000054691.6
forkhead box C2
chr18_+_50051702 0.64 ENSMUST00000134348.1
ENSMUST00000153873.2
tumor necrosis factor, alpha-induced protein 8
chr13_-_58354862 0.62 ENSMUST00000043605.5
kinesin family member 27
chr10_+_97482350 0.62 ENSMUST00000163448.2
decorin
chr9_-_123678873 0.60 ENSMUST00000040960.6
solute carrier family 6 (neurotransmitter transporter), member 20A
chr12_-_113361232 0.60 ENSMUST00000103423.1
Immunoglobulin heavy constant gamma 3
chr19_-_38043559 0.60 ENSMUST00000041475.8
ENSMUST00000172095.2
myoferlin
chr9_-_107872403 0.60 ENSMUST00000183035.1
RNA binding motif protein 6
chr1_-_65123108 0.60 ENSMUST00000050047.3
ENSMUST00000148020.1
RIKEN cDNA D630023F18 gene
chr7_-_46667375 0.59 ENSMUST00000107669.2
tryptophan hydroxylase 1
chr9_-_123678782 0.59 ENSMUST00000170591.1
ENSMUST00000171647.1
solute carrier family 6 (neurotransmitter transporter), member 20A
chr6_+_122513643 0.57 ENSMUST00000118626.1
microfibrillar associated protein 5
chrX_+_94636066 0.56 ENSMUST00000096368.3
G1 to S phase transition 2
chr3_-_106219477 0.54 ENSMUST00000082219.5
chitinase 3-like 4
chr7_+_99594605 0.54 ENSMUST00000162290.1
arrestin, beta 1
chr9_-_49798729 0.54 ENSMUST00000166811.2
neural cell adhesion molecule 1
chr4_+_147132038 0.53 ENSMUST00000084149.3
predicted gene 13139
chr1_+_46066738 0.53 ENSMUST00000069293.7
dynein, axonemal, heavy chain 7B
chr16_+_45224315 0.50 ENSMUST00000102802.3
ENSMUST00000063654.4
B and T lymphocyte associated
chr9_+_72806874 0.50 ENSMUST00000055535.8
protogenin homolog (Gallus gallus)
chr4_+_103143052 0.50 ENSMUST00000106855.1
mesoderm induction early response 1 homolog (Xenopus laevis
chr14_-_15438974 0.48 ENSMUST00000055211.4
leucine rich repeat containing 3B
chr2_+_148681199 0.48 ENSMUST00000131292.1
GDNF-inducible zinc finger protein 1
chr6_+_122513583 0.48 ENSMUST00000032210.7
ENSMUST00000148517.1
microfibrillar associated protein 5
chr7_+_43427622 0.47 ENSMUST00000177164.2
lens intrinsic membrane protein 2
chr17_-_78684262 0.46 ENSMUST00000145480.1
striatin, calmodulin binding protein
chr13_-_102905740 0.46 ENSMUST00000167462.1
microtubule associated serine/threonine kinase family member 4
chr9_-_14381242 0.46 ENSMUST00000167549.1
endonuclease domain containing 1
chrX_+_153139941 0.45 ENSMUST00000039720.4
ENSMUST00000144175.2
Ras-related GTP binding B
chr15_-_93595877 0.44 ENSMUST00000048982.4
prickle homolog 1 (Drosophila)
chr14_-_103844173 0.44 ENSMUST00000022718.3
endothelin receptor type B
chr12_+_79297345 0.44 ENSMUST00000079533.5
ENSMUST00000171210.1
RAD51 homolog B
chr9_+_57504012 0.43 ENSMUST00000080514.7
ribonuclease P/MRP 25 subunit
chr17_+_82539258 0.43 ENSMUST00000097278.3
predicted pseudogene 6594
chr3_-_41742471 0.43 ENSMUST00000026866.8
sodium channel and clathrin linker 1
chr2_+_11705287 0.42 ENSMUST00000135341.1
ENSMUST00000138349.1
ENSMUST00000123600.2
interleukin 15 receptor, alpha chain
chr2_+_86007778 0.42 ENSMUST00000062166.1
olfactory receptor 1032
chr5_-_138170992 0.42 ENSMUST00000139983.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chrX_+_109196750 0.42 ENSMUST00000139259.1
ENSMUST00000060013.3
predicted gene 6377
chr17_+_21691860 0.41 ENSMUST00000072133.4
predicted gene 10226
chr6_-_87533219 0.40 ENSMUST00000113637.2
ENSMUST00000071024.6
Rho GTPase activating protein 25
chr4_-_147809788 0.40 ENSMUST00000105734.3
ENSMUST00000176201.1
predicted gene 13157
predicted gene 20707
chr10_+_23851454 0.39 ENSMUST00000020190.7
vanin 3
chr19_+_23723279 0.39 ENSMUST00000067077.1
predicted gene 9938
chr14_+_26894557 0.37 ENSMUST00000090337.4
ENSMUST00000165929.2
ankyrin repeat and SOCS box-containing 14
chr14_-_104522615 0.37 ENSMUST00000022716.2
ring finger protein 219
chr10_+_94575257 0.37 ENSMUST00000121471.1
transmembrane and coiled coil domains 3
chr2_-_20943413 0.36 ENSMUST00000140230.1
Rho GTPase activating protein 21
chr6_-_42710036 0.36 ENSMUST00000045054.4
family with sequence similarity 115, member A
chr6_-_3399545 0.34 ENSMUST00000120087.3
sterile alpha motif domain containing 9-like
chr1_+_106980979 0.34 ENSMUST00000027564.1
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 13
chr13_+_109926832 0.34 ENSMUST00000117420.1
phosphodiesterase 4D, cAMP specific
chr2_-_125782834 0.33 ENSMUST00000053699.6
SECIS binding protein 2-like
chr8_+_57332111 0.33 ENSMUST00000181638.1
RIKEN cDNA 5033428I22 gene
chr4_+_32657107 0.33 ENSMUST00000071642.4
ENSMUST00000178134.1
midasin homolog (yeast)
chr17_-_56036546 0.33 ENSMUST00000003268.9
SH3-domain GRB2-like 1
chr14_-_103843685 0.33 ENSMUST00000172237.1
endothelin receptor type B
chr1_-_158356258 0.33 ENSMUST00000004133.8
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr5_+_90794530 0.33 ENSMUST00000031322.6
chemokine (C-X-C motif) ligand 15
chrX_+_9885622 0.32 ENSMUST00000067529.2
ENSMUST00000086165.3
synaptotagmin-like 5
chr13_+_97482701 0.31 ENSMUST00000179324.1
predicted gene 2373
chr6_-_129678908 0.31 ENSMUST00000118447.1
ENSMUST00000169545.1
ENSMUST00000032270.6
ENSMUST00000032271.6
killer cell lectin-like receptor subfamily C, member 1
chr11_+_67200137 0.31 ENSMUST00000129018.1
myosin, heavy polypeptide 1, skeletal muscle, adult
chr11_-_17953861 0.31 ENSMUST00000076661.6
Ewing's tumor-associated antigen 1
chr3_+_88081997 0.31 ENSMUST00000071812.5
IQ motif containing GTPase activating protein 3
chr6_+_37870786 0.30 ENSMUST00000120428.1
ENSMUST00000031859.7
tripartite motif-containing 24
chr2_+_131491764 0.30 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
spermine oxidase
chr8_-_61902669 0.30 ENSMUST00000121785.1
ENSMUST00000034057.7
palladin, cytoskeletal associated protein
chr7_+_30493622 0.29 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
proline dehydrogenase (oxidase) 2
chr6_+_11926758 0.29 ENSMUST00000133776.1
PHD finger protein 14
chr14_+_53757356 0.29 ENSMUST00000180380.1
T cell receptor alpha variable 13-4-DV7
chr16_-_19286837 0.29 ENSMUST00000056727.4
olfactory receptor 164
chr9_-_22259887 0.28 ENSMUST00000086281.4
zinc finger protein 599
chr9_-_35558522 0.28 ENSMUST00000034612.5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr16_-_16829276 0.28 ENSMUST00000023468.5
sperm associated antigen 6
chr8_-_122915987 0.28 ENSMUST00000098333.4
ankyrin repeat domain 11
chr11_+_105092194 0.27 ENSMUST00000021029.5
EF-hand calcium binding domain 3
chr5_+_130369420 0.27 ENSMUST00000086029.3
calneuron 1
chr3_+_41742615 0.27 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
DNA segment, Chr 3, ERATO Doi 751, expressed
chr10_+_116966274 0.26 ENSMUST00000033651.3
RIKEN cDNA D630029K05 gene
chr14_+_51129055 0.26 ENSMUST00000095923.3
ribonuclease, RNase A family, 6
chr9_+_7571396 0.26 ENSMUST00000120900.1
ENSMUST00000093896.3
ENSMUST00000151853.1
ENSMUST00000152878.1
matrix metallopeptidase 27
chr1_-_150164943 0.26 ENSMUST00000181308.1
predicted gene, 26687
chr4_+_146610961 0.25 ENSMUST00000130825.1
predicted gene 13248
chr6_+_52714219 0.25 ENSMUST00000138040.1
ENSMUST00000129660.1
Tax1 (human T cell leukemia virus type I) binding protein 1
chr10_+_115384951 0.25 ENSMUST00000036044.8
zinc finger, C3H1-type containing
chr3_+_107291215 0.25 ENSMUST00000029502.7
solute carrier family 16 (monocarboxylic acid transporters), member 4
chr19_-_41077106 0.25 ENSMUST00000087176.6
oligodendrocytic myelin paranodal and inner loop protein
chr5_-_138171248 0.24 ENSMUST00000153867.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr15_+_99006056 0.24 ENSMUST00000079818.3
predicted gene 8973
chr7_-_46667303 0.24 ENSMUST00000168335.1
tryptophan hydroxylase 1
chr6_-_28397999 0.24 ENSMUST00000035930.4
zinc finger protein 800
chr14_-_47394253 0.23 ENSMUST00000177822.1
discs, large (Drosophila) homolog-associated protein 5
chr9_-_18385981 0.23 ENSMUST00000166825.1
N-acetylated alpha-linked acidic dipeptidase 2
chr2_+_150323702 0.23 ENSMUST00000133235.2
predicted gene 10130
chr4_+_32623985 0.23 ENSMUST00000108178.1
caspase 8 associated protein 2
chr1_-_138175126 0.23 ENSMUST00000183301.1
protein tyrosine phosphatase, receptor type, C
chr9_+_13619990 0.23 ENSMUST00000159294.1
mastermind like 2 (Drosophila)
chr18_-_15403680 0.23 ENSMUST00000079081.6
aquaporin 4
chr2_-_13491900 0.23 ENSMUST00000091436.5
cubilin (intrinsic factor-cobalamin receptor)
chr8_+_21427456 0.22 ENSMUST00000095424.4
predicted gene, 21498
chr7_-_126976092 0.22 ENSMUST00000181859.1
RIKEN cDNA D830044I16 gene
chr6_+_145934113 0.21 ENSMUST00000032383.7
sarcospan
chr2_+_11705355 0.21 ENSMUST00000128156.2
interleukin 15 receptor, alpha chain
chr8_+_93810832 0.21 ENSMUST00000034198.8
ENSMUST00000125716.1
guanine nucleotide binding protein, alpha O
chr2_-_177267036 0.21 ENSMUST00000108963.1
predicted gene 14409
chr1_-_135585314 0.21 ENSMUST00000040599.8
ENSMUST00000067414.6
neuron navigator 1
chr13_+_77135513 0.21 ENSMUST00000168779.1
RIKEN cDNA 2210408I21 gene
chr4_+_145510759 0.21 ENSMUST00000105742.1
ENSMUST00000136309.1
predicted gene 13225
chr7_+_39588931 0.21 ENSMUST00000178791.1
ENSMUST00000098511.3
predicted gene 2058
chr18_+_12972225 0.20 ENSMUST00000025290.5
imprinted and ancient
chr6_-_129507107 0.20 ENSMUST00000183258.1
ENSMUST00000182784.1
ENSMUST00000032265.6
ENSMUST00000162815.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr7_+_29170345 0.20 ENSMUST00000033886.7
gametogenetin
chr14_+_51552790 0.20 ENSMUST00000096170.4
predicted gene 5622
chr3_-_62506970 0.20 ENSMUST00000029336.4
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr1_+_174041933 0.20 ENSMUST00000052975.4
olfactory receptor 433
chr18_+_53551594 0.19 ENSMUST00000115398.1
PR domain containing 6
chr9_+_72958785 0.19 ENSMUST00000098567.2
ENSMUST00000034734.8
dyslexia susceptibility 1 candidate 1 homolog (human)
chr1_+_53061637 0.19 ENSMUST00000027269.5
myostatin
chr17_+_32993123 0.19 ENSMUST00000087666.4
ENSMUST00000157017.1
zinc finger protein 952
chr5_-_138171216 0.18 ENSMUST00000147920.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr11_-_109995775 0.18 ENSMUST00000020948.8
ATP-binding cassette, sub-family A (ABC1), member 8b
chr12_-_87443800 0.18 ENSMUST00000162961.1
alkB, alkylation repair homolog 1 (E. coli)
chr7_-_143649614 0.18 ENSMUST00000129476.1
ENSMUST00000084396.3
ENSMUST00000075588.6
ENSMUST00000146692.1
tumor necrosis factor receptor superfamily, member 22
chr5_+_3543812 0.18 ENSMUST00000115527.3
family with sequence similarity 133, member B
chr11_-_109995743 0.18 ENSMUST00000106669.2
ATP-binding cassette, sub-family A (ABC1), member 8b
chr7_+_29170204 0.18 ENSMUST00000098609.2
gametogenetin
chr5_+_107497718 0.17 ENSMUST00000112671.2
RIKEN cDNA A830010M20 gene
chr8_+_21025545 0.17 ENSMUST00000076754.2
defensin, alpha, 21
chr5_-_62766153 0.17 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr6_-_122340499 0.17 ENSMUST00000160843.1
polyhomeotic-like 1 (Drosophila)
chr15_-_82794236 0.17 ENSMUST00000006094.4
cytochrome P450, family 2, subfamily d, polypeptide 26
chr6_-_128275577 0.16 ENSMUST00000130454.1
TEA domain family member 4
chr15_-_50882806 0.16 ENSMUST00000184885.1
trichorhinophalangeal syndrome I (human)
chr3_+_142620596 0.15 ENSMUST00000165774.1
guanylate binding protein 2
chr3_-_117077760 0.15 ENSMUST00000029642.5
RIKEN cDNA 1700061I17 gene
chr11_-_107337556 0.15 ENSMUST00000040380.6
phosphatidylinositol transfer protein, cytoplasmic 1
chr6_-_115037824 0.14 ENSMUST00000174848.1
ENSMUST00000032461.5
TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)
chr9_+_64281575 0.14 ENSMUST00000034964.6
timeless interacting protein
chr15_+_34453285 0.14 ENSMUST00000060894.7
cDNA sequence BC030476
chr8_+_13869641 0.14 ENSMUST00000051870.7
ENSMUST00000128557.1
chromosome alignment maintaining phosphoprotein 1
chr2_+_36230426 0.14 ENSMUST00000062069.5
prostaglandin-endoperoxide synthase 1
chr16_+_92478743 0.14 ENSMUST00000160494.1
RIKEN cDNA 2410124H12 gene
chr14_-_52213379 0.13 ENSMUST00000140603.1
chromodomain helicase DNA binding protein 8
chr8_-_27413937 0.13 ENSMUST00000033882.8
cholinergic receptor, nicotinic, alpha polypeptide 6
chr8_-_83442648 0.13 ENSMUST00000167525.1
short coiled-coil protein
chr2_-_85675173 0.13 ENSMUST00000099917.1
olfactory receptor 1006

Network of associatons between targets according to the STRING database.

First level regulatory network of Lhx5_Lmx1b_Lhx1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
0.6 1.7 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.6 1.7 GO:1902870 camera-type eye photoreceptor cell fate commitment(GO:0060220) negative regulation of neural retina development(GO:0061076) negative regulation of retina development in camera-type eye(GO:1902867) negative regulation of amacrine cell differentiation(GO:1902870)
0.5 2.4 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.5 1.4 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.4 4.0 GO:0016554 cytidine to uridine editing(GO:0016554)
0.4 3.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.4 2.8 GO:1901748 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.3 0.9 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.3 1.2 GO:0035524 proline transmembrane transport(GO:0035524)
0.2 0.7 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.2 0.7 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.9 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.2 0.7 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.2 0.6 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 0.9 GO:0021824 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)
0.1 0.4 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.1 22.6 GO:0007586 digestion(GO:0007586)
0.1 1.5 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.1 1.3 GO:0032275 luteinizing hormone secretion(GO:0032275)
0.1 0.8 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.1 1.0 GO:0030916 otic vesicle formation(GO:0030916)
0.1 0.8 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.9 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.9 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 0.3 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.3 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 1.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.5 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.6 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 2.9 GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum(GO:0010880)
0.1 0.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.1 0.4 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.2 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 3.7 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.1 0.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.1 GO:0042415 norepinephrine metabolic process(GO:0042415)
0.1 0.2 GO:0070295 renal water absorption(GO:0070295)
0.0 0.3 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.7 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.2 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.0 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.0 0.5 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.2 GO:0035552 tRNA wobble cytosine modification(GO:0002101) oxidative single-stranded DNA demethylation(GO:0035552)
0.0 0.1 GO:0032811 negative regulation of epinephrine secretion(GO:0032811)
0.0 0.3 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.3 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.6 GO:0001778 plasma membrane repair(GO:0001778)
0.0 1.0 GO:0035634 response to stilbenoid(GO:0035634)
0.0 1.0 GO:0097435 fibril organization(GO:0097435)
0.0 0.3 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.3 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.5 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.2 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.7 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.5 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.2 GO:0036337 Fas signaling pathway(GO:0036337)
0.0 0.2 GO:1901078 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 1.9 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.1 GO:0033382 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.6 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.0 0.5 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.9 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:0038027 apolipoprotein A-I-mediated signaling pathway(GO:0038027) regulation of engulfment of apoptotic cell(GO:1901074)
0.0 0.3 GO:0010818 T cell chemotaxis(GO:0010818)
0.0 0.3 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.6 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414) regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:2000849 glucocorticoid secretion(GO:0035933) regulation of glucocorticoid secretion(GO:2000849)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.0 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0033603 positive regulation of dopamine secretion(GO:0033603)
0.0 0.0 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0033193 Lsd1/2 complex(GO:0033193)
0.2 3.7 GO:0042581 specific granule(GO:0042581)
0.2 0.6 GO:0018444 translation release factor complex(GO:0018444)
0.2 0.7 GO:0060187 cell pole(GO:0060187)
0.2 1.7 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 3.5 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.1 0.9 GO:0005927 muscle tendon junction(GO:0005927)
0.1 2.6 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.5 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 0.4 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 1.0 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.1 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 0.5 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.2 GO:0032982 muscle myosin complex(GO:0005859) myosin filament(GO:0032982)
0.0 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.3 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.4 GO:0071439 clathrin complex(GO:0071439)
0.0 0.7 GO:0000346 transcription export complex(GO:0000346)
0.0 0.6 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.6 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 31.1 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0042629 mast cell granule(GO:0042629)
0.0 1.5 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.2 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0005914 spot adherens junction(GO:0005914)
0.0 0.2 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 1.0 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.3 0.8 GO:0004962 endothelin receptor activity(GO:0004962)
0.2 2.8 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.2 0.9 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.2 0.5 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 6.1 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 3.0 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 1.2 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.2 GO:0051430 mu-type opioid receptor binding(GO:0031852) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 21.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.3 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 1.9 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 2.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.6 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 1.4 GO:0030275 LRR domain binding(GO:0030275)
0.1 0.4 GO:0000150 recombinase activity(GO:0000150)
0.1 0.9 GO:0038191 neuropilin binding(GO:0038191) chemorepellent activity(GO:0045499)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 1.1 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.3 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.5 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.2 GO:0030492 hemoglobin binding(GO:0030492)
0.0 1.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0043734 DNA-N1-methyladenine dioxygenase activity(GO:0043734)
0.0 0.2 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.2 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.9 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.6 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.2 GO:0005179 hormone activity(GO:0005179)
0.0 0.5 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0090556 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 1.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.9 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0023023 MHC protein complex binding(GO:0023023)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0071949 FAD binding(GO:0071949)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 3.1 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 9.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 3.1 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.4 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.5 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.3 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.6 PID FGF PATHWAY FGF signaling pathway
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 3.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 0.8 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 2.8 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 0.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.9 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.6 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 1.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 1.1 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins