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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Irf2_Irf1_Irf8_Irf9_Irf7

Z-value: 1.87

Motif logo

Transcription factors associated with Irf2_Irf1_Irf8_Irf9_Irf7

Gene Symbol Gene ID Gene Info
ENSMUSG00000031627.7 interferon regulatory factor 2
ENSMUSG00000018899.10 interferon regulatory factor 1
ENSMUSG00000041515.3 interferon regulatory factor 8
ENSMUSG00000002325.8 interferon regulatory factor 9
ENSMUSG00000025498.8 interferon regulatory factor 7

Activity-expression correlation:

Activity profile of Irf2_Irf1_Irf8_Irf9_Irf7 motif

Sorted Z-values of Irf2_Irf1_Irf8_Irf9_Irf7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_77729091 33.28 ENSMUST00000109775.2
apolipoprotein L 9b
chr1_+_130826676 19.85 ENSMUST00000027675.7
polymeric immunoglobulin receptor
chr1_+_130826762 18.74 ENSMUST00000133792.1
polymeric immunoglobulin receptor
chr15_-_77411034 17.58 ENSMUST00000089452.5
ENSMUST00000081776.3
apolipoprotein L 9a
chr2_-_173218879 16.47 ENSMUST00000109116.2
ENSMUST00000029018.7
Z-DNA binding protein 1
chr4_+_42629719 14.27 ENSMUST00000166898.2
predicted gene 2564
chr8_-_71537402 13.78 ENSMUST00000051672.7
bone marrow stromal cell antigen 2
chr19_+_34607927 13.35 ENSMUST00000076249.5
RIKEN cDNA I830012O16 gene
chr8_-_45333189 12.55 ENSMUST00000095328.4
cytochrome P450, family 4, subfamily v, polypeptide 3
chr19_+_34640871 12.19 ENSMUST00000102824.3
interferon-induced protein with tetratricopeptide repeats 1
chr18_+_60212080 12.06 ENSMUST00000031549.5
predicted gene 4951
chr2_+_122147680 11.55 ENSMUST00000102476.4
beta-2 microglobulin
chr19_-_11050500 11.53 ENSMUST00000099676.4
expressed sequence AW112010
chr5_-_105239533 11.52 ENSMUST00000065588.6
guanylate-binding protein 10
chr11_+_70459940 10.96 ENSMUST00000147289.1
ENSMUST00000126105.1
zinc finger, MYND-type containing 15
chr11_+_70459611 10.76 ENSMUST00000039093.3
zinc finger, MYND-type containing 15
chr7_-_141010759 10.64 ENSMUST00000026565.6
interferon induced transmembrane protein 3
chr11_+_49087022 10.50 ENSMUST00000046704.6
interferon gamma inducible protein 47
chr1_-_162984519 10.16 ENSMUST00000028010.7
flavin containing monooxygenase 3
chr3_-_151749877 9.57 ENSMUST00000029671.7
interferon-induced protein 44
chr19_+_34583528 9.53 ENSMUST00000102825.3
interferon-induced protein with tetratricopeptide repeats 3
chr16_+_43363855 9.38 ENSMUST00000156367.1
zinc finger and BTB domain containing 20
chr10_+_40629987 9.22 ENSMUST00000019977.7
D-aspartate oxidase
chr16_+_23609895 8.61 ENSMUST00000038423.5
receptor transporter protein 4
chr8_-_84773381 8.45 ENSMUST00000109764.1
nuclear factor I/X
chr3_-_113574758 8.44 ENSMUST00000106540.1
amylase 1, salivary
chr3_-_113574242 8.28 ENSMUST00000142505.2
amylase 1, salivary
chr7_-_141266415 8.27 ENSMUST00000106023.1
ENSMUST00000097952.2
ENSMUST00000026571.4
interferon regulatory factor 7
chr12_+_103434211 8.11 ENSMUST00000079294.5
ENSMUST00000076788.5
ENSMUST00000076702.5
ENSMUST00000066701.6
ENSMUST00000085065.5
ENSMUST00000140838.1
interferon, alpha-inducible protein 27
chr11_-_53859187 8.09 ENSMUST00000117316.1
ENSMUST00000120776.1
ENSMUST00000121435.1
predicted gene 12216
chr11_-_49064202 8.00 ENSMUST00000046745.6
T cell specific GTPase 2
chr11_-_48992226 7.97 ENSMUST00000059930.2
ENSMUST00000068063.3
predicted gene 12185
T cell specific GTPase 1
chr2_+_102706356 7.86 ENSMUST00000123759.1
ENSMUST00000111212.1
ENSMUST00000005220.4
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_-_14446570 7.85 ENSMUST00000063509.4
RIKEN cDNA 2810007J24 gene
chr15_-_77596110 7.77 ENSMUST00000089465.4
apolipoprotein L 10B
chr15_-_77533312 7.74 ENSMUST00000062562.5
apolipoprotein L 7c
chr9_+_20868628 7.64 ENSMUST00000043911.7
RIKEN cDNA A230050P20 gene
chr7_-_14446651 7.58 ENSMUST00000125941.1
RIKEN cDNA 2810007J24 gene
chr1_+_52119438 7.54 ENSMUST00000070968.7
signal transducer and activator of transcription 1
chr17_-_36042690 7.44 ENSMUST00000058801.8
ENSMUST00000080015.5
ENSMUST00000077960.6
histocompatibility 2, T region locus 22
chr9_-_106476104 7.43 ENSMUST00000156426.1
poly (ADP-ribose) polymerase family, member 3
chr9_-_106476372 7.40 ENSMUST00000123555.1
ENSMUST00000125850.1
poly (ADP-ribose) polymerase family, member 3
chr17_-_34187219 7.36 ENSMUST00000173831.1
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr3_+_142620596 7.28 ENSMUST00000165774.1
guanylate binding protein 2
chr18_+_60376029 7.18 ENSMUST00000066912.5
ENSMUST00000032473.6
interferon inducible GTPase 1
chr9_-_106476590 7.15 ENSMUST00000112479.2
poly (ADP-ribose) polymerase family, member 3
chr1_-_173599074 7.13 ENSMUST00000150649.1
ENSMUST00000180215.1
ENSMUST00000097462.2
pyrin domain containing 4
chr1_+_167618246 7.03 ENSMUST00000111380.1
retinoid X receptor gamma
chr4_-_42756543 6.88 ENSMUST00000102957.3
chemokine (C-C motif) ligand 19
chr9_+_77921908 6.45 ENSMUST00000133757.1
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr16_+_97536079 6.44 ENSMUST00000024112.7
myxovirus (influenza virus) resistance 2
chr17_-_34862122 6.41 ENSMUST00000154526.1
complement factor B
chr11_-_48871408 6.36 ENSMUST00000097271.2
immunity-related GTPase family M member 1
chr5_+_114923234 6.34 ENSMUST00000031540.4
ENSMUST00000112143.3
2'-5' oligoadenylate synthetase-like 1
chr6_-_23839137 6.32 ENSMUST00000166458.2
ENSMUST00000142913.2
ENSMUST00000115357.1
ENSMUST00000069074.7
ENSMUST00000115361.2
ENSMUST00000018122.7
ENSMUST00000115355.1
ENSMUST00000115356.2
Ca2+-dependent activator protein for secretion 2
chr11_-_48871344 6.30 ENSMUST00000049519.3
immunity-related GTPase family M member 1
chr6_-_39118211 6.22 ENSMUST00000038398.6
poly (ADP-ribose) polymerase family, member 12
chr4_-_42773993 6.19 ENSMUST00000095114.4
chemokine (C-C motif) ligand 21A (serine)
chr11_-_70459957 6.16 ENSMUST00000019064.2
chemokine (C-X-C motif) ligand 16
chr1_+_175631996 6.00 ENSMUST00000040250.8
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chrX_+_59999436 6.00 ENSMUST00000033477.4
coagulation factor IX
chr11_+_72301613 5.99 ENSMUST00000151440.1
ENSMUST00000146233.1
ENSMUST00000140842.2
XIAP associated factor 1
chr1_-_150466165 5.99 ENSMUST00000162367.1
ENSMUST00000161611.1
ENSMUST00000161320.1
ENSMUST00000159035.1
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr11_+_119393060 5.94 ENSMUST00000131035.2
ENSMUST00000093902.5
ring finger protein 213
chr3_+_142560052 5.90 ENSMUST00000106222.2
guanylate binding protein 3
chr1_+_175632169 5.89 ENSMUST00000097458.3
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr1_+_173673651 5.86 ENSMUST00000085876.4
pyrin domain containing 3
chr17_+_36121666 5.67 ENSMUST00000173128.1
predicted gene, 19684
chr4_+_42255767 5.66 ENSMUST00000178864.1
chemokine (C-C motif) ligand 21B (leucine)
chr6_-_23839420 5.58 ENSMUST00000115358.2
ENSMUST00000163871.2
Ca2+-dependent activator protein for secretion 2
chr17_-_34862473 5.57 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
complement factor B
chr4_-_40239779 5.51 ENSMUST00000037907.6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr2_-_51972990 5.48 ENSMUST00000145481.1
ENSMUST00000112705.2
N-myc (and STAT) interactor
chr3_+_142560351 5.44 ENSMUST00000106221.1
guanylate binding protein 3
chr5_-_105293699 5.41 ENSMUST00000050011.8
guanylate binding protein 6
chr3_+_142560108 5.41 ENSMUST00000128609.1
ENSMUST00000029935.7
guanylate binding protein 3
chr6_+_121245903 5.39 ENSMUST00000032198.9
ubiquitin specific peptidase 18
chr7_+_51878967 5.34 ENSMUST00000051912.6
growth arrest specific 2
chr17_+_34187545 5.31 ENSMUST00000170086.1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr2_-_126933229 5.25 ENSMUST00000028844.4
signal peptide peptidase like 2A
chr8_+_61928081 5.22 ENSMUST00000154398.1
ENSMUST00000093485.2
ENSMUST00000156980.1
ENSMUST00000070631.7
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr11_+_58199556 5.09 ENSMUST00000035266.4
ENSMUST00000094169.4
ENSMUST00000168280.1
ENSMUST00000058704.8
interferon gamma induced GTPase
immunity-related GTPase family M member 2
chr17_+_34187789 5.09 ENSMUST00000041633.8
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr7_+_51879041 4.91 ENSMUST00000107591.2
growth arrest specific 2
chr1_+_156035705 4.87 ENSMUST00000111754.2
ENSMUST00000133152.1
torsin A interacting protein 2
chr19_+_56397100 4.85 ENSMUST00000026062.9
caspase 7
chr2_-_77170534 4.81 ENSMUST00000111833.2
coiled-coil domain containing 141
chr11_-_100704217 4.76 ENSMUST00000017974.6
DEXH (Asp-Glu-X-His) box polypeptide 58
chr2_-_62646146 4.75 ENSMUST00000112459.3
ENSMUST00000028259.5
interferon induced with helicase C domain 1
chr16_+_43364145 4.73 ENSMUST00000148775.1
zinc finger and BTB domain containing 20
chr6_+_128662379 4.61 ENSMUST00000032518.4
C-type lectin domain family 2, member h
chr3_+_60081861 4.60 ENSMUST00000029326.5
succinate receptor 1
chr6_+_57580992 4.60 ENSMUST00000031817.8
hect domain and RLD 6
chr4_+_41903610 4.58 ENSMUST00000098128.3
predicted gene, 21541
chr4_+_42114817 4.57 ENSMUST00000098123.3
predicted gene 13304
chr16_+_35938470 4.56 ENSMUST00000114878.1
poly (ADP-ribose) polymerase family, member 9
chr15_+_99392882 4.56 ENSMUST00000023749.8
transmembrane BAX inhibitor motif containing 6
chr15_-_76243401 4.52 ENSMUST00000165738.1
ENSMUST00000075689.6
poly (ADP-ribose) polymerase family, member 10
chr7_+_119526269 4.51 ENSMUST00000066465.1
acyl-CoA synthetase medium-chain family member 5
chr6_-_85869128 4.45 ENSMUST00000045008.7
camello-like 2
chr18_-_60273267 4.44 ENSMUST00000090260.4
predicted gene 4841
chr18_-_61536522 4.43 ENSMUST00000171629.1
Rho guanine nucleotide exchange factor (GEF) 37
chr2_+_58755177 4.34 ENSMUST00000102755.3
uridine phosphorylase 2
chr13_+_4434306 4.29 ENSMUST00000021630.8
aldo-keto reductase family 1, member C6
chr17_-_34000257 4.29 ENSMUST00000087189.6
ENSMUST00000173075.1
ENSMUST00000172760.1
ENSMUST00000172912.1
ENSMUST00000025181.10
histocompatibility 2, K1, K region
chr13_+_4059565 4.26 ENSMUST00000041768.6
aldo-keto reductase family 1, member C14
chr16_-_24393588 4.21 ENSMUST00000181640.1
RIKEN cDNA 1110054M08 gene
chr2_+_58754910 4.21 ENSMUST00000059102.6
uridine phosphorylase 2
chr16_+_35938972 4.19 ENSMUST00000023622.6
ENSMUST00000114877.1
poly (ADP-ribose) polymerase family, member 9
chr3_+_142594847 4.10 ENSMUST00000029936.4
guanylate binding protein 2b
chr11_-_78984946 4.09 ENSMUST00000108268.3
lectin, galactose binding, soluble 9
chr3_-_98630309 4.02 ENSMUST00000044094.4
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5
chr5_-_92348871 4.01 ENSMUST00000038816.6
ENSMUST00000118006.1
chemokine (C-X-C motif) ligand 10
chr17_+_33919332 3.99 ENSMUST00000025161.7
TAP binding protein
chr9_+_5345450 3.96 ENSMUST00000151332.1
caspase 12
chr1_-_153851189 3.94 ENSMUST00000059607.6
RIKEN cDNA 5830403L16 gene
chr4_-_46536096 3.94 ENSMUST00000102924.2
tripartite motif-containing 14
chr4_-_46536134 3.91 ENSMUST00000046897.6
tripartite motif-containing 14
chr1_-_173490933 3.90 ENSMUST00000160565.2
predicted gene 4955
chr9_+_5345414 3.88 ENSMUST00000027009.4
caspase 12
chr11_+_58215028 3.87 ENSMUST00000108836.1
immunity-related GTPase family M member 2
chr8_-_105938384 3.84 ENSMUST00000034369.8
proteasome (prosome, macropain) subunit, beta type 10
chr8_-_93279717 3.82 ENSMUST00000034178.8
carboxylesterase 1F
chr14_-_7994563 3.81 ENSMUST00000026315.7
deoxyribonuclease 1-like 3
chr18_-_3299537 3.75 ENSMUST00000129435.1
ENSMUST00000122958.1
cAMP responsive element modulator
chr10_-_34127955 3.69 ENSMUST00000062784.6
family with sequence similarity 26, member F
chr1_+_13668739 3.66 ENSMUST00000088542.3
X Kell blood group precursor related family member 9 homolog
chr17_+_37193889 3.64 ENSMUST00000038844.6
ubiquitin D
chr2_+_72054598 3.58 ENSMUST00000028525.5
Rap guanine nucleotide exchange factor (GEF) 4
chr6_-_31218421 3.58 ENSMUST00000115107.1
cDNA sequence AB041803
chr11_-_78984831 3.50 ENSMUST00000073001.4
ENSMUST00000108269.3
lectin, galactose binding, soluble 9
chr6_-_125231772 3.48 ENSMUST00000043422.7
TAP binding protein-like
chr13_-_23710714 3.46 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
hemochromatosis
chr1_-_172590463 3.44 ENSMUST00000065679.6
SLAM family member 8
chr6_+_34745952 3.41 ENSMUST00000123823.1
ENSMUST00000136907.1
ENSMUST00000126181.1
caldesmon 1
chr2_+_68117713 3.40 ENSMUST00000112346.2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr2_-_24049389 3.38 ENSMUST00000051416.5
histamine N-methyltransferase
chr7_+_104244449 3.38 ENSMUST00000106849.2
ENSMUST00000060315.5
tripartite motif-containing 34A
chr17_+_35439155 3.37 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
histocompatibility 2, Q region locus 7
chr5_+_67260794 3.29 ENSMUST00000161369.1
transmembrane protein 33
chr8_+_70083509 3.24 ENSMUST00000007738.9
hyaluronan and proteoglycan link protein 4
chr1_+_156035392 3.21 ENSMUST00000111757.3
torsin A interacting protein 2
chr7_+_104244465 3.21 ENSMUST00000106848.1
tripartite motif-containing 34A
chr2_-_51973219 3.19 ENSMUST00000028314.2
N-myc (and STAT) interactor
chr15_+_75862310 3.18 ENSMUST00000023238.4
gasdermin D
chr16_-_35939082 3.18 ENSMUST00000081933.7
ENSMUST00000114885.1
deltex 3-like (Drosophila)
chr13_+_51846673 3.11 ENSMUST00000021903.2
growth arrest and DNA-damage-inducible 45 gamma
chr7_+_107567445 3.11 ENSMUST00000120990.1
olfactomedin-like 1
chr7_+_104244496 3.05 ENSMUST00000106854.1
ENSMUST00000143414.1
tripartite motif-containing 34A
chr3_+_27317028 2.96 ENSMUST00000046383.5
ENSMUST00000174840.1
tumor necrosis factor (ligand) superfamily, member 10
chr3_+_142530329 2.94 ENSMUST00000171263.1
ENSMUST00000045097.9
guanylate binding protein 7
chr15_-_76014318 2.91 ENSMUST00000060807.5
family with sequence similarity 83, member H
chr6_+_124512615 2.90 ENSMUST00000068593.7
complement component 1, r subcomponent A
chr13_+_33004528 2.90 ENSMUST00000006391.4
serine (or cysteine) peptidase inhibitor, clade B, member 9
chr3_+_81932601 2.83 ENSMUST00000029649.2
cathepsin O
chr4_+_135728116 2.83 ENSMUST00000102546.3
interleukin 22 receptor, alpha 1
chr5_-_105139539 2.81 ENSMUST00000100961.4
ENSMUST00000031235.6
ENSMUST00000100962.3
guanylate-binding protein 9
guanylate-binding protein 8
guanylate binding protein 4
chr18_-_3299452 2.81 ENSMUST00000126578.1
cAMP responsive element modulator
chr1_-_155146755 2.80 ENSMUST00000027744.8
major histocompatibility complex, class I-related
chr13_+_74639866 2.76 ENSMUST00000169114.1
endoplasmic reticulum aminopeptidase 1
chr12_+_37241633 2.75 ENSMUST00000049874.7
alkylglycerol monooxygenase
chr5_-_105110292 2.74 ENSMUST00000031238.6
guanylate-binding protein 9
chr2_+_43555321 2.70 ENSMUST00000028223.2
kynureninase (L-kynurenine hydrolase)
chr4_-_40239700 2.69 ENSMUST00000142055.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr6_-_38354243 2.68 ENSMUST00000114900.1
zinc finger CCCH type, antiviral 1
chr19_-_7966000 2.68 ENSMUST00000182102.1
ENSMUST00000075619.4
solute carrier family 22, member 27
chr12_+_37241729 2.67 ENSMUST00000160768.1
alkylglycerol monooxygenase
chr18_+_60293372 2.66 ENSMUST00000171297.1
RIKEN cDNA F830016B08 gene
chr15_-_76307101 2.66 ENSMUST00000171340.1
5-oxoprolinase (ATP-hydrolysing)
chr5_-_91402905 2.64 ENSMUST00000121044.2
betacellulin, epidermal growth factor family member
chr3_-_86999284 2.64 ENSMUST00000063869.5
ENSMUST00000029717.2
CD1d1 antigen
chr16_+_26581704 2.63 ENSMUST00000096129.2
ENSMUST00000166294.2
ENSMUST00000174202.1
ENSMUST00000023156.6
interleukin 1 receptor accessory protein
chr3_+_142496924 2.61 ENSMUST00000090127.2
guanylate binding protein 5
chr9_-_50555170 2.60 ENSMUST00000119103.1
beta-carotene oxygenase 2
chr10_+_39612934 2.59 ENSMUST00000019987.6
TRAF3 interacting protein 2
chr8_-_3748941 2.58 ENSMUST00000012847.1
CD209a antigen
chr2_+_43555342 2.57 ENSMUST00000112826.1
ENSMUST00000050511.6
kynureninase (L-kynurenine hydrolase)
chr1_+_130865669 2.57 ENSMUST00000038829.5
Fas apoptotic inhibitory molecule 3
chr2_-_126783416 2.57 ENSMUST00000130356.1
ENSMUST00000028842.2
ubiquitin specific peptidase 50
chr2_+_27676440 2.55 ENSMUST00000129514.1
retinoid X receptor alpha
chr17_+_35262730 2.55 ENSMUST00000172785.1
histocompatibility 2, D region locus 1
chr17_+_35470083 2.51 ENSMUST00000174525.1
ENSMUST00000068291.6
histocompatibility 2, Q region locus 10
chr12_+_37242030 2.50 ENSMUST00000160390.1
alkylglycerol monooxygenase
chr6_-_54972603 2.49 ENSMUST00000060655.8
nucleotide-binding oligomerization domain containing 1
chr8_-_111338152 2.46 ENSMUST00000056157.7
ENSMUST00000120432.1
mixed lineage kinase domain-like
chr14_+_41105359 2.46 ENSMUST00000047286.6
methionine adenosyltransferase I, alpha
chr10_-_92375367 2.40 ENSMUST00000182870.1
predicted gene, 20757
chr19_+_8898090 2.39 ENSMUST00000096246.3
alpha glucosidase 2 alpha neutral subunit
chr17_+_31433054 2.37 ENSMUST00000136384.1
phosphodiesterase 9A
chr8_-_3878549 2.36 ENSMUST00000011445.6
CD209d antigen
chr10_+_128270546 2.34 ENSMUST00000105238.3
ENSMUST00000085708.2
signal transducer and activator of transcription 2
chr8_-_84800024 2.34 ENSMUST00000126806.1
ENSMUST00000076715.6
nuclear factor I/X
chr19_-_24861828 2.34 ENSMUST00000047666.4
phosphoglucomutase 5
chr8_-_84800344 2.33 ENSMUST00000099070.3
nuclear factor I/X
chr4_+_155582476 2.32 ENSMUST00000105612.1
NAD kinase
chr2_-_77170592 2.32 ENSMUST00000164114.2
ENSMUST00000049544.7
coiled-coil domain containing 141
chr3_+_138313279 2.30 ENSMUST00000013455.6
ENSMUST00000106247.1
alcohol dehydrogenase 6A (class V)
chr10_+_4611971 2.29 ENSMUST00000105590.1
ENSMUST00000067086.7
estrogen receptor 1 (alpha)
chr19_-_21472552 2.28 ENSMUST00000087600.3
guanine deaminase
chr2_+_19371636 2.28 ENSMUST00000023856.8
methionine sulfoxide reductase B2

Network of associatons between targets according to the STRING database.

First level regulatory network of Irf2_Irf1_Irf8_Irf9_Irf7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.6 38.6 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
7.3 22.0 GO:1990166 protein localization to site of double-strand break(GO:1990166)
4.4 13.1 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
3.5 3.5 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
3.5 41.6 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
3.3 10.0 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
3.1 176.4 GO:0035456 response to interferon-beta(GO:0035456)
3.1 9.2 GO:0006533 aspartate catabolic process(GO:0006533)
2.9 8.7 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
2.9 17.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
2.8 8.3 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
2.1 2.1 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
2.0 12.2 GO:0035549 interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549)
2.0 10.0 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
1.9 17.1 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
1.8 9.0 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
1.6 4.9 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
1.6 6.4 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
1.5 4.5 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
1.5 11.9 GO:1990504 dense core granule exocytosis(GO:1990504)
1.5 1.5 GO:0002488 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489)
1.4 4.3 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
1.3 5.3 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
1.3 3.8 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
1.1 3.4 GO:0019883 antigen processing and presentation of endogenous antigen(GO:0019883)
1.1 7.9 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
1.0 2.9 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.9 3.6 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.9 3.5 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.9 70.7 GO:0034341 response to interferon-gamma(GO:0034341)
0.8 2.5 GO:0018900 dichloromethane metabolic process(GO:0018900)
0.8 13.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.8 14.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.8 2.3 GO:0046098 guanine metabolic process(GO:0046098)
0.7 6.0 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.7 8.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.7 4.4 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.7 9.5 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.7 3.4 GO:1902623 leukocyte chemotaxis involved in inflammatory response(GO:0002232) negative regulation of neutrophil migration(GO:1902623)
0.7 2.0 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.7 5.2 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.7 2.0 GO:0060809 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.6 8.0 GO:0097264 self proteolysis(GO:0097264)
0.6 2.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.6 1.8 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.6 1.1 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.6 2.3 GO:0030091 protein repair(GO:0030091)
0.6 1.7 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.6 1.7 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.5 1.6 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.5 6.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.5 2.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.5 1.0 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
0.5 2.1 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.5 2.6 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.5 8.0 GO:0046485 ether lipid metabolic process(GO:0046485)
0.5 1.5 GO:0006542 glutamine biosynthetic process(GO:0006542)
0.5 3.4 GO:0052805 imidazole-containing compound catabolic process(GO:0052805)
0.5 9.0 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.5 1.4 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.4 0.4 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.4 17.7 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.4 3.5 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 2.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.4 2.2 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.4 2.5 GO:0003383 apical constriction(GO:0003383)
0.4 11.5 GO:0035634 response to stilbenoid(GO:0035634)
0.4 1.2 GO:0032474 otolith morphogenesis(GO:0032474) otolith development(GO:0048840)
0.4 0.8 GO:0071649 regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.4 2.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 0.8 GO:0071332 cellular response to fructose stimulus(GO:0071332)
0.4 1.1 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.4 12.2 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.4 2.3 GO:0060751 Sertoli cell proliferation(GO:0060011) prostate epithelial cord elongation(GO:0060523) epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750) branch elongation involved in mammary gland duct branching(GO:0060751)
0.4 1.5 GO:0010901 negative regulation of cytokine secretion involved in immune response(GO:0002740) regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.4 1.5 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.4 3.8 GO:0042095 interferon-gamma biosynthetic process(GO:0042095)
0.4 10.2 GO:0017144 drug metabolic process(GO:0017144)
0.4 1.1 GO:0006011 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.4 0.7 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.4 0.7 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.3 1.0 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.3 1.4 GO:0032385 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.3 1.7 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.3 1.0 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.3 7.9 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.3 2.6 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.3 0.9 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.3 2.8 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.3 1.8 GO:0044375 regulation of peroxisome size(GO:0044375)
0.3 0.9 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.3 0.3 GO:2000836 positive regulation of androgen secretion(GO:2000836)
0.3 2.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.3 2.6 GO:0072602 interleukin-4 secretion(GO:0072602)
0.3 2.0 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.3 1.4 GO:0070495 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
0.3 1.7 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.3 1.1 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.3 0.5 GO:0038086 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.3 1.6 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.3 1.3 GO:0045351 type I interferon biosynthetic process(GO:0045351)
0.3 1.6 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.3 2.6 GO:0035810 positive regulation of urine volume(GO:0035810)
0.3 1.6 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.3 0.8 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.3 4.3 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.3 13.2 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.3 1.8 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.3 7.0 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.2 2.2 GO:0060337 type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.2 2.2 GO:0032494 response to peptidoglycan(GO:0032494)
0.2 1.0 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.2 0.7 GO:0006553 lysine metabolic process(GO:0006553)
0.2 1.7 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.2 1.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 0.7 GO:0060220 camera-type eye photoreceptor cell fate commitment(GO:0060220) negative regulation of neural retina development(GO:0061076) negative regulation of retina development in camera-type eye(GO:1902867) negative regulation of amacrine cell differentiation(GO:1902870)
0.2 0.2 GO:0018307 enzyme active site formation(GO:0018307)
0.2 0.7 GO:1901026 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.2 1.4 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.2 2.9 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 0.2 GO:2000793 cell proliferation involved in heart valve development(GO:2000793)
0.2 0.4 GO:0071316 cellular response to nicotine(GO:0071316)
0.2 1.2 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.2 1.2 GO:0015889 cobalamin transport(GO:0015889)
0.2 0.4 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.2 1.5 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.2 0.2 GO:2000911 positive regulation of cholesterol import(GO:1904109) positive regulation of sterol import(GO:2000911)
0.2 0.9 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 0.4 GO:0070933 histone H4 deacetylation(GO:0070933)
0.2 1.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.2 1.8 GO:0014029 neural crest formation(GO:0014029)
0.2 1.8 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.2 1.4 GO:0097475 motor neuron migration(GO:0097475)
0.2 1.8 GO:0003374 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.2 1.1 GO:0033227 dsRNA transport(GO:0033227)
0.2 0.5 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.2 0.7 GO:0006624 vacuolar protein processing(GO:0006624)
0.2 0.9 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.2 0.7 GO:0034769 basement membrane disassembly(GO:0034769)
0.2 0.7 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.2 0.8 GO:1901098 positive regulation of autophagosome maturation(GO:1901098)
0.2 3.0 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.2 2.5 GO:2000778 positive regulation of interleukin-6 secretion(GO:2000778)
0.2 0.8 GO:0098886 modification of dendritic spine(GO:0098886)
0.2 0.3 GO:0048687 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.2 0.5 GO:0051030 RNA import into nucleus(GO:0006404) snRNA transport(GO:0051030)
0.2 7.8 GO:0019882 antigen processing and presentation(GO:0019882)
0.2 0.5 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.2 2.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.2 0.5 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.2 0.5 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 0.6 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.2 0.8 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.2 2.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.1 1.9 GO:0032836 glomerular basement membrane development(GO:0032836)
0.1 1.5 GO:0021678 third ventricle development(GO:0021678)
0.1 0.9 GO:1901317 regulation of sperm motility(GO:1901317)
0.1 1.5 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 2.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.1 5.5 GO:0051642 centrosome localization(GO:0051642)
0.1 1.1 GO:0035902 response to immobilization stress(GO:0035902)
0.1 1.9 GO:0019321 pentose metabolic process(GO:0019321)
0.1 4.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.1 1.6 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 1.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.1 0.4 GO:0071288 substrate-dependent cell migration, cell attachment to substrate(GO:0006931) calcium-independent cell-matrix adhesion(GO:0007161) cellular response to mercury ion(GO:0071288)
0.1 2.4 GO:0006491 N-glycan processing(GO:0006491)
0.1 1.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.1 1.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.4 GO:0003360 brainstem development(GO:0003360)
0.1 0.5 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 1.9 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 3.0 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.1 1.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 1.0 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 15.3 GO:0019395 fatty acid oxidation(GO:0019395)
0.1 0.5 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 2.6 GO:0061462 protein localization to lysosome(GO:0061462)
0.1 1.5 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.1 4.3 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.1 0.8 GO:0060613 fat pad development(GO:0060613)
0.1 2.2 GO:0046931 pore complex assembly(GO:0046931)
0.1 1.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.1 4.5 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.4 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 19.0 GO:0007286 spermatid development(GO:0007286)
0.1 1.0 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.3 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1 1.2 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.1 0.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 0.7 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.3 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 1.5 GO:0015747 urate transport(GO:0015747)
0.1 0.7 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.7 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.7 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.4 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.7 GO:0008053 mitochondrial fusion(GO:0008053)
0.1 0.8 GO:0048245 mast cell chemotaxis(GO:0002551) eosinophil chemotaxis(GO:0048245)
0.1 0.8 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.7 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.1 0.5 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.3 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.1 0.5 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.8 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.5 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.1 0.5 GO:0060278 regulation of ovulation(GO:0060278)
0.1 0.8 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.1 0.8 GO:0034116 positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.1 1.0 GO:0031953 negative regulation of protein autophosphorylation(GO:0031953)
0.1 2.1 GO:0019433 triglyceride catabolic process(GO:0019433)
0.1 1.9 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.1 0.6 GO:0006983 ER overload response(GO:0006983)
0.1 1.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 10.8 GO:0016052 carbohydrate catabolic process(GO:0016052)
0.1 1.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.6 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 1.2 GO:0072189 ureter development(GO:0072189)
0.1 0.4 GO:0090168 Golgi reassembly(GO:0090168)
0.1 1.7 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.2 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.1 0.9 GO:0061318 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.1 0.4 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.1 0.5 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.1 0.7 GO:0007343 egg activation(GO:0007343)
0.1 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.2 GO:0021852 pyramidal neuron migration(GO:0021852)
0.1 0.5 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.1 1.0 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.1 1.3 GO:0051923 sulfation(GO:0051923)
0.1 0.6 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.1 2.8 GO:0044380 protein localization to cytoskeleton(GO:0044380)
0.1 1.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 0.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.6 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.7 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.1 3.0 GO:0006695 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.1 4.5 GO:0006637 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 0.9 GO:0008298 intracellular mRNA localization(GO:0008298)
0.1 0.4 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.1 0.7 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.6 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996) regulation of establishment of protein localization to plasma membrane(GO:0090003)
0.1 0.9 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.6 GO:0009062 fatty acid catabolic process(GO:0009062)
0.1 1.2 GO:0015813 L-glutamate transport(GO:0015813)
0.1 2.4 GO:0010390 histone monoubiquitination(GO:0010390)
0.1 1.6 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 0.1 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 0.7 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.1 2.2 GO:0071526 semaphorin-plexin signaling pathway(GO:0071526)
0.1 0.3 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.1 0.8 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.1 GO:0042339 keratan sulfate metabolic process(GO:0042339)
0.1 0.1 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1 0.5 GO:0002755 MyD88-dependent toll-like receptor signaling pathway(GO:0002755)
0.1 0.4 GO:0015808 L-alanine transport(GO:0015808)
0.1 1.0 GO:0032689 negative regulation of interferon-gamma production(GO:0032689)
0.1 0.2 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.3 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.5 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.9 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.5 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.3 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.4 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.8 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.2 GO:1903999 regulation of eating behavior(GO:1903998) negative regulation of eating behavior(GO:1903999) regulation of defecation(GO:2000292) negative regulation of defecation(GO:2000293)
0.0 0.9 GO:0043984 histone H4-K16 acetylation(GO:0043984)
0.0 1.1 GO:0007635 chemosensory behavior(GO:0007635)
0.0 0.3 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.2 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.5 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 3.0 GO:0030193 regulation of blood coagulation(GO:0030193) regulation of hemostasis(GO:1900046)
0.0 0.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 1.0 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 5.8 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.1 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 1.0 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 3.4 GO:0032092 positive regulation of protein binding(GO:0032092)
0.0 0.4 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.3 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 2.0 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.3 GO:0017121 phospholipid scrambling(GO:0017121)
0.0 0.5 GO:1903541 regulation of exosomal secretion(GO:1903541) positive regulation of exosomal secretion(GO:1903543)
0.0 0.6 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.8 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.9 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.8 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.9 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 1.1 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 2.3 GO:0006006 glucose metabolic process(GO:0006006)
0.0 0.1 GO:0021623 oculomotor nerve morphogenesis(GO:0021622) oculomotor nerve formation(GO:0021623)
0.0 0.6 GO:0007143 female meiotic division(GO:0007143)
0.0 1.0 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.0 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.4 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.7 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 1.1 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.9 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.1 GO:0051096 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 0.2 GO:0009214 cyclic nucleotide catabolic process(GO:0009214)
0.0 6.1 GO:0009116 nucleoside metabolic process(GO:0009116)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.0 0.1 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.3 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.2 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.2 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.2 GO:1902306 negative regulation of sodium ion transmembrane transport(GO:1902306) negative regulation of sodium ion transmembrane transporter activity(GO:2000650)
0.0 0.1 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.2 GO:0045779 negative regulation of bone resorption(GO:0045779)
0.0 0.4 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0 0.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.6 GO:0050775 positive regulation of dendrite morphogenesis(GO:0050775)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0002154 thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 0.2 GO:0046337 phosphatidylethanolamine metabolic process(GO:0046337)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 1.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.0 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.2 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.0 GO:0006583 melanin biosynthetic process from tyrosine(GO:0006583)
0.0 0.3 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.0 0.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.2 GO:0006903 vesicle targeting(GO:0006903)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0090272 negative regulation of fibroblast growth factor production(GO:0090272)
0.0 0.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.0 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.0 GO:0042695 thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744)
0.0 0.1 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.3 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 58.2 GO:0020003 symbiont-containing vacuole(GO:0020003)
2.7 32.3 GO:0042612 MHC class I protein complex(GO:0042612)
2.2 11.2 GO:1990111 spermatoproteasome complex(GO:1990111)
2.1 17.0 GO:0042825 TAP complex(GO:0042825)
1.6 6.5 GO:0097447 dendritic tree(GO:0097447)
1.1 8.6 GO:0045098 type III intermediate filament(GO:0045098)
0.9 14.1 GO:0044754 autolysosome(GO:0044754)
0.9 38.6 GO:0055038 recycling endosome membrane(GO:0055038)
0.9 5.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.9 7.8 GO:0030478 actin cap(GO:0030478)
0.7 3.6 GO:0044316 cone cell pedicle(GO:0044316)
0.6 1.1 GO:0030870 Mre11 complex(GO:0030870)
0.5 2.3 GO:0005914 spot adherens junction(GO:0005914)
0.4 2.6 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.4 3.5 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.4 1.2 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.4 17.0 GO:0035861 site of double-strand break(GO:0035861)
0.4 1.9 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.3 2.3 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.3 1.9 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.3 2.5 GO:0033269 internode region of axon(GO:0033269)
0.3 2.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.3 2.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.3 1.5 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.3 3.0 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.3 1.2 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.3 1.5 GO:0071986 Ragulator complex(GO:0071986)
0.3 0.8 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.3 1.0 GO:0043202 lysosomal lumen(GO:0043202)
0.2 2.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 23.0 GO:0042734 presynaptic membrane(GO:0042734)
0.2 0.7 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 0.7 GO:0000814 ESCRT II complex(GO:0000814)
0.2 0.9 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 6.8 GO:0048770 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 2.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.2 1.2 GO:0045293 mRNA editing complex(GO:0045293)
0.2 3.6 GO:0016235 aggresome(GO:0016235)
0.2 1.4 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.2 2.4 GO:0042611 MHC protein complex(GO:0042611)
0.2 1.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.2 0.9 GO:0072487 MSL complex(GO:0072487)
0.2 0.8 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.2 1.2 GO:0070695 FHF complex(GO:0070695)
0.1 6.5 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.4 GO:0043512 inhibin A complex(GO:0043512)
0.1 1.2 GO:0005839 proteasome core complex(GO:0005839)
0.1 1.7 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 3.2 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.4 GO:0043186 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.1 1.0 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.4 GO:0044307 dendritic branch(GO:0044307)
0.1 1.2 GO:0005579 membrane attack complex(GO:0005579)
0.1 16.6 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.1 1.7 GO:0043196 varicosity(GO:0043196)
0.1 1.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 50.3 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.1 17.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.4 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110) CNTFR-CLCF1 complex(GO:0097059)
0.1 3.0 GO:0045095 keratin filament(GO:0045095)
0.1 0.4 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.1 1.6 GO:0031527 filopodium membrane(GO:0031527)
0.1 0.3 GO:0071942 XPC complex(GO:0071942)
0.1 1.8 GO:0005922 connexon complex(GO:0005922)
0.1 0.5 GO:0051286 cell tip(GO:0051286)
0.1 0.2 GO:1990462 omegasome(GO:1990462)
0.1 0.4 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 5.5 GO:0005811 lipid particle(GO:0005811)
0.1 10.6 GO:0072562 blood microparticle(GO:0072562)
0.1 1.2 GO:0000124 SAGA complex(GO:0000124)
0.1 3.2 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.0 GO:0017119 Golgi transport complex(GO:0017119)
0.1 1.2 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 0.8 GO:0045179 apical cortex(GO:0045179)
0.1 1.4 GO:0033270 paranode region of axon(GO:0033270)
0.1 0.4 GO:0001520 outer dense fiber(GO:0001520)
0.1 0.6 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.1 0.3 GO:0005726 perichromatin fibrils(GO:0005726)
0.1 0.5 GO:0030061 mitochondrial crista(GO:0030061)
0.1 0.5 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.4 GO:0042587 glycogen granule(GO:0042587)
0.1 1.7 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 6.0 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 1.2 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.6 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.5 GO:0005642 annulate lamellae(GO:0005642)
0.0 20.4 GO:0045177 apical part of cell(GO:0045177)
0.0 0.5 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 2.1 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 5.6 GO:0005923 bicellular tight junction(GO:0005923)
0.0 6.4 GO:0005770 late endosome(GO:0005770)
0.0 0.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.9 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 3.9 GO:0005604 basement membrane(GO:0005604)
0.0 2.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.7 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0097441 basilar dendrite(GO:0097441)
0.0 2.4 GO:0031301 integral component of organelle membrane(GO:0031301)
0.0 0.9 GO:0030175 filopodium(GO:0030175)
0.0 27.3 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.3 GO:0070069 cytochrome complex(GO:0070069)
0.0 1.6 GO:0030662 coated vesicle membrane(GO:0030662)
0.0 0.7 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.5 GO:0033176 proton-transporting V-type ATPase complex(GO:0033176)
0.0 3.4 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0036156 inner dynein arm(GO:0036156)
0.0 7.7 GO:0031966 mitochondrial membrane(GO:0031966)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 1.4 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 4.6 GO:0043235 receptor complex(GO:0043235)
0.0 2.6 GO:0000139 Golgi membrane(GO:0000139)
0.0 66.1 GO:0005829 cytosol(GO:0005829)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 26.7 GO:0005615 extracellular space(GO:0005615)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 2.1 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.4 GO:0005902 microvillus(GO:0005902)
0.0 1.7 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.9 GO:0000922 spindle pole(GO:0000922)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0055037 recycling endosome(GO:0055037)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.2 15.5 GO:0003692 left-handed Z-DNA binding(GO:0003692)
3.9 39.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
2.6 7.9 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
2.4 22.0 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
2.4 17.0 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
2.4 16.7 GO:0004556 alpha-amylase activity(GO:0004556)
2.3 9.2 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
2.2 8.6 GO:0031849 olfactory receptor binding(GO:0031849)
2.0 24.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
2.0 11.9 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
1.7 6.9 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
1.7 8.6 GO:0004850 uridine phosphorylase activity(GO:0004850)
1.7 10.0 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
1.4 4.3 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
1.4 4.3 GO:0047023