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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hsf4

Z-value: 1.45

Motif logo

Transcription factors associated with Hsf4

Gene Symbol Gene ID Gene Info
ENSMUSG00000033249.4 heat shock transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hsf4mm10_v2_chr8_+_105269837_1052698740.563.5e-04Click!

Activity profile of Hsf4 motif

Sorted Z-values of Hsf4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_8131982 8.48 ENSMUST00000065651.4
solute carrier family 22, member 28
chr19_-_8405060 6.56 ENSMUST00000064507.5
ENSMUST00000120540.1
ENSMUST00000096269.4
solute carrier family 22, member 30
chr6_-_138073196 4.02 ENSMUST00000050132.3
solute carrier family 15, member 5
chr7_+_140845562 3.44 ENSMUST00000035300.5
secretoglobin, family 1C, member 1
chr19_+_58670358 3.42 ENSMUST00000057270.7
pancreatic lipase
chr10_+_76562270 3.22 ENSMUST00000009259.4
ENSMUST00000105414.1
spermatogenesis and centriole associated 1 like
chr6_-_128438673 3.00 ENSMUST00000032508.4
FK506 binding protein 4
chr12_-_110696289 2.99 ENSMUST00000021698.6
heat shock protein 90, alpha (cytosolic), class A member 1
chr18_-_10706688 2.92 ENSMUST00000002549.7
ENSMUST00000117726.1
ENSMUST00000117828.1
abhydrolase domain containing 3
chr1_+_195017399 2.91 ENSMUST00000181273.1
RIKEN cDNA A330023F24 gene
chr17_+_35439155 2.86 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
histocompatibility 2, Q region locus 7
chr3_-_107943390 2.80 ENSMUST00000106681.1
glutathione S-transferase, mu 6
chr7_-_114562945 2.79 ENSMUST00000119712.1
ENSMUST00000032908.8
cytochrome P450, family 2, subfamily r, polypeptide 1
chr5_-_149636164 2.75 ENSMUST00000076410.4
heat shock 105kDa/110kDa protein 1
chr5_+_151368683 2.72 ENSMUST00000181114.1
ENSMUST00000181555.1
RIKEN cDNA 1700028E10 gene
chr7_-_25539845 2.62 ENSMUST00000066503.7
ENSMUST00000064862.6
carcinoembryonic antigen-related cell adhesion molecule 2
chr3_-_107943362 2.56 ENSMUST00000106683.1
glutathione S-transferase, mu 6
chr7_-_25539950 2.55 ENSMUST00000044547.8
carcinoembryonic antigen-related cell adhesion molecule 2
chrX_-_38635066 2.53 ENSMUST00000058265.7
C1GALT1-specific chaperone 1
chr12_-_110695860 2.35 ENSMUST00000149189.1
heat shock protein 90, alpha (cytosolic), class A member 1
chr4_+_40722461 2.34 ENSMUST00000030118.3
DnaJ (Hsp40) homolog, subfamily A, member 1
chr5_-_28055440 2.33 ENSMUST00000181503.1
predicted gene, 26608
chr7_-_119523477 2.31 ENSMUST00000033267.2
protein disulfide isomerase-like, testis expressed
chr11_-_106579111 2.26 ENSMUST00000103070.2
testis expressed gene 2
chr17_+_35470083 2.24 ENSMUST00000174525.1
ENSMUST00000068291.6
histocompatibility 2, Q region locus 10
chr8_-_45382198 2.18 ENSMUST00000093526.6
family with sequence similarity 149, member A
chr12_-_110696248 2.15 ENSMUST00000124156.1
heat shock protein 90, alpha (cytosolic), class A member 1
chr10_+_75893398 2.11 ENSMUST00000009236.4
Der1-like domain family, member 3
chr17_+_35424870 2.05 ENSMUST00000113879.3
histocompatibility 2, Q region locus 6
chr5_+_92555035 2.02 ENSMUST00000146417.2
family with sequence similarity 47, member E
chr5_-_45450221 2.01 ENSMUST00000015950.5
quinoid dihydropteridine reductase
chr5_-_45450143 2.00 ENSMUST00000154962.1
quinoid dihydropteridine reductase
chr8_-_71537402 1.99 ENSMUST00000051672.7
bone marrow stromal cell antigen 2
chr19_+_3986564 1.98 ENSMUST00000054030.7
aspartoacylase (aminoacylase) 3
chr19_-_5802640 1.97 ENSMUST00000173523.1
ENSMUST00000173499.1
ENSMUST00000172812.2
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr5_-_66151903 1.93 ENSMUST00000167950.1
RNA binding motif protein 47
chr6_-_83677807 1.88 ENSMUST00000037882.6
CD207 antigen
chr5_-_45450121 1.88 ENSMUST00000127562.1
quinoid dihydropteridine reductase
chr5_+_135887905 1.81 ENSMUST00000005077.6
heat shock protein 1
chr5_+_135887988 1.81 ENSMUST00000111155.1
heat shock protein 1
chr17_+_35424842 1.80 ENSMUST00000174699.1
histocompatibility 2, Q region locus 6
chr17_+_3326552 1.79 ENSMUST00000169838.1
T cell lymphoma invasion and metastasis 2
chr7_-_24236632 1.76 ENSMUST00000037448.6
zinc finger protein 109
chr10_+_29313500 1.76 ENSMUST00000020034.4
enoyl Coenzyme A hydratase domain containing 1
chr10_-_86705485 1.73 ENSMUST00000020238.7
heat shock protein 90, beta (Grp94), member 1
chr7_+_44198191 1.72 ENSMUST00000085450.2
kallikrein 1-related peptidase b3
chr15_+_62039216 1.71 ENSMUST00000183297.1
plasmacytoma variant translocation 1
chr19_-_7802578 1.70 ENSMUST00000120522.1
ENSMUST00000065634.7
solute carrier family 22 (organic cation transporter), member 26
chr6_-_59024470 1.69 ENSMUST00000089860.5
family with sequence similarity 13, member A
chr5_-_151369172 1.64 ENSMUST00000067770.3
RIKEN cDNA D730045B01 gene
chr13_-_23574196 1.64 ENSMUST00000105106.1
histone cluster 1, H2bf
chr4_+_155601414 1.62 ENSMUST00000105608.2
solute carrier family 35, member E2
chr17_+_3532554 1.61 ENSMUST00000168560.1
claudin 20
chrX_-_73716145 1.61 ENSMUST00000002091.5
B cell receptor associated protein 31
chr1_+_88087802 1.58 ENSMUST00000113139.1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr11_-_23497867 1.58 ENSMUST00000128559.1
ENSMUST00000147157.1
ENSMUST00000109539.1
AHA1, activator of heat shock protein ATPase 2
chr18_-_3337539 1.57 ENSMUST00000142690.1
ENSMUST00000025069.4
ENSMUST00000082141.5
ENSMUST00000165086.1
ENSMUST00000149803.1
cAMP responsive element modulator
chr18_-_3337614 1.57 ENSMUST00000150235.1
ENSMUST00000154470.1
cAMP responsive element modulator
chr6_+_3993776 1.55 ENSMUST00000031673.5
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr2_-_28466266 1.55 ENSMUST00000127683.1
ENSMUST00000086370.4
RIKEN cDNA 1700007K13 gene
chr16_+_23107413 1.52 ENSMUST00000023599.6
ENSMUST00000168891.1
eukaryotic translation initiation factor 4A2
chr12_+_112106683 1.51 ENSMUST00000079400.4
asparaginase homolog (S. cerevisiae)
chr8_+_109990430 1.50 ENSMUST00000001720.7
ENSMUST00000143741.1
tyrosine aminotransferase
chr9_-_105495130 1.49 ENSMUST00000038118.7
ATPase, Ca++-sequestering
chr10_-_39163794 1.49 ENSMUST00000076713.4
WNT1 inducible signaling pathway protein 3
chr3_+_114904062 1.49 ENSMUST00000081752.6
olfactomedin 3
chr12_-_110696332 1.46 ENSMUST00000094361.4
heat shock protein 90, alpha (cytosolic), class A member 1
chr7_+_30712209 1.45 ENSMUST00000005692.6
ENSMUST00000170371.1
ATPase, H+/K+ exchanging, gastric, alpha polypeptide
chr11_+_21239279 1.44 ENSMUST00000006221.7
ENSMUST00000109578.1
vacuolar protein sorting 54 (yeast)
chr2_+_116900152 1.43 ENSMUST00000126467.1
ENSMUST00000128305.1
ENSMUST00000155323.1
RIKEN cDNA D330050G23 gene
chr1_+_88095054 1.42 ENSMUST00000150634.1
ENSMUST00000058237.7
UDP glucuronosyltransferase 1 family, polypeptide A7C
chr19_-_44069526 1.40 ENSMUST00000170801.1
ER lipid raft associated 1
chrX_-_74023908 1.39 ENSMUST00000033769.8
ENSMUST00000114352.1
ENSMUST00000068286.5
ENSMUST00000114360.3
ENSMUST00000114354.3
interleukin-1 receptor-associated kinase 1
chr16_+_23107754 1.37 ENSMUST00000077605.5
ENSMUST00000115341.3
eukaryotic translation initiation factor 4A2
chr17_-_12675833 1.37 ENSMUST00000024596.8
solute carrier family 22 (organic cation transporter), member 1
chr17_+_35262730 1.37 ENSMUST00000172785.1
histocompatibility 2, D region locus 1
chr7_-_46715676 1.35 ENSMUST00000006956.7
serum amyloid A 3
chr15_+_33083110 1.33 ENSMUST00000042167.9
carboxypeptidase Q
chr17_-_45592569 1.31 ENSMUST00000163492.1
solute carrier family 29 (nucleoside transporters), member 1
chrX_-_74023745 1.30 ENSMUST00000114353.3
ENSMUST00000101458.2
interleukin-1 receptor-associated kinase 1
chr17_-_12916345 1.30 ENSMUST00000079121.3
mitochondrial ribosomal protein L18
chr19_-_29812952 1.29 ENSMUST00000099525.3
RAN binding protein 6
chr2_+_172472512 1.28 ENSMUST00000029007.2
family with sequence similarity 209
chr19_+_47854970 1.28 ENSMUST00000026050.7
glutathione S-transferase omega 1
chr6_+_125049952 1.27 ENSMUST00000088294.5
ENSMUST00000032481.7
proacrosin binding protein
chr8_-_22398588 1.27 ENSMUST00000033871.6
solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15
chr11_-_26210553 1.26 ENSMUST00000101447.3
RIKEN cDNA 5730522E02 gene
chr13_-_111490111 1.25 ENSMUST00000047627.7
GC-rich promoter binding protein 1
chr6_-_59024340 1.24 ENSMUST00000173193.1
family with sequence similarity 13, member A
chr19_-_44069690 1.23 ENSMUST00000169092.1
ER lipid raft associated 1
chr16_-_88751628 1.23 ENSMUST00000053149.2
keratin associated protein 13
chr4_-_40722307 1.22 ENSMUST00000181475.1
predicted gene 6297
chrX_-_109013389 1.22 ENSMUST00000033597.8
high-mobility group nucleosome binding domain 5
chr15_-_81399594 1.19 ENSMUST00000023039.8
suppression of tumorigenicity 13
chr9_-_105495037 1.17 ENSMUST00000176190.1
ENSMUST00000163879.2
ENSMUST00000112558.2
ENSMUST00000176390.1
ATPase, Ca++-sequestering
chr2_-_175133322 1.16 ENSMUST00000099029.3
predicted gene 14399
chr6_-_124888192 1.16 ENSMUST00000024044.6
CD4 antigen
chr3_+_79591356 1.15 ENSMUST00000029382.7
peptidylprolyl isomerase D (cyclophilin D)
chr5_+_92331828 1.14 ENSMUST00000125462.1
ENSMUST00000121096.1
ENSMUST00000113083.2
ADP-ribosyltransferase 3
chr5_-_123749393 1.12 ENSMUST00000057795.5
ENSMUST00000111515.1
ENSMUST00000182309.1
arginine/serine-rich coiled-coil 2
chr13_-_111490028 1.12 ENSMUST00000091236.4
GC-rich promoter binding protein 1
chr8_-_120177440 1.12 ENSMUST00000048786.6
family with sequence similarity 92, member B
chr4_+_129287614 1.10 ENSMUST00000102599.3
syncoilin
chr4_-_135385645 1.07 ENSMUST00000105857.1
ENSMUST00000105858.1
ENSMUST00000064481.8
ENSMUST00000123632.1
noncompact myelin associated protein
chr3_+_30792876 1.07 ENSMUST00000029256.7
SEC62 homolog (S. cerevisiae)
chr7_+_119895836 1.07 ENSMUST00000106518.1
ENSMUST00000054440.3
LYR motif containing 1
chr11_-_12412136 1.07 ENSMUST00000174874.1
cordon-bleu WH2 repeat
chr5_-_149636331 1.06 ENSMUST00000074846.7
ENSMUST00000110498.1
ENSMUST00000127977.1
ENSMUST00000132412.1
heat shock 105kDa/110kDa protein 1
chr5_+_92331818 1.05 ENSMUST00000154245.1
ADP-ribosyltransferase 3
chr13_-_51203065 1.05 ENSMUST00000091708.4
histone cluster 1, H2al
chr8_-_84893887 1.05 ENSMUST00000003907.7
ENSMUST00000182458.1
ENSMUST00000109745.1
ENSMUST00000142748.1
glutaryl-Coenzyme A dehydrogenase
chr17_+_21491256 1.04 ENSMUST00000076664.6
zinc finger protein 53
chr4_+_155601854 1.03 ENSMUST00000118607.1
solute carrier family 35, member E2
chr13_-_48273865 1.03 ENSMUST00000180777.1
RIKEN cDNA A330048O09 gene
chr15_-_3995708 1.03 ENSMUST00000046633.8
expressed sequence AW549877
chr9_-_105521147 1.02 ENSMUST00000176770.1
ENSMUST00000085133.6
ATPase, Ca++-sequestering
chr17_-_56121946 1.02 ENSMUST00000041357.7
leucine-rich alpha-2-glycoprotein 1
chr9_+_120149733 1.02 ENSMUST00000068698.7
ENSMUST00000093773.1
ENSMUST00000111627.1
myelin-associated oligodendrocytic basic protein
chr5_+_30281377 1.02 ENSMUST00000101448.3
dynein regulatory complex subunit 1
chr9_+_75410145 1.00 ENSMUST00000180533.1
ENSMUST00000180574.1
RIKEN cDNA 4933433G15 gene
chr4_-_96507386 1.00 ENSMUST00000124729.3
cytochrome P450, family 2, subfamily j, polypeptide 8
chr9_+_18292267 0.99 ENSMUST00000001825.7
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
chr7_+_43995833 0.98 ENSMUST00000007156.4
kallikrein 1-related peptidase b11
chr10_+_81268172 0.98 ENSMUST00000057798.8
amyloid beta (A4) precursor protein-binding, family A, member 3
chr9_-_109162021 0.97 ENSMUST00000120329.1
ENSMUST00000054925.6
F-box and WD-40 domain protein 21
chr4_+_148140699 0.97 ENSMUST00000140049.1
ENSMUST00000105707.1
MAD2 mitotic arrest deficient-like 2
chr10_-_86011833 0.96 ENSMUST00000105304.1
ENSMUST00000061699.5
BPI fold containing family C
chr8_-_3748941 0.95 ENSMUST00000012847.1
CD209a antigen
chr5_-_123749371 0.95 ENSMUST00000182955.1
ENSMUST00000182489.1
ENSMUST00000050827.7
arginine/serine-rich coiled-coil 2
chr11_+_21091291 0.94 ENSMUST00000093290.5
pellino 1
chrX_+_21714896 0.93 ENSMUST00000033414.7
solute carrier family 6 (neurotransmitter transporter), member 14
chr15_-_81400043 0.92 ENSMUST00000172107.1
ENSMUST00000169204.1
ENSMUST00000163382.1
suppression of tumorigenicity 13
chr5_-_137962955 0.92 ENSMUST00000077119.6
gap junction protein, gamma 3
chr4_+_40722912 0.91 ENSMUST00000164233.1
ENSMUST00000137246.1
ENSMUST00000125442.1
DnaJ (Hsp40) homolog, subfamily A, member 1
chr13_+_81657732 0.90 ENSMUST00000049055.6
LysM, putative peptidoglycan-binding, domain containing 3
chr15_-_82690499 0.90 ENSMUST00000100380.3
cytochrome P450, family 2, subfamily d, polypeptide 37, pseudogene
chr12_-_79172609 0.90 ENSMUST00000055262.6
vesicle transport through interaction with t-SNAREs 1B
chr5_-_50058908 0.90 ENSMUST00000030971.5
G protein-coupled receptor 125
chr2_-_110314525 0.88 ENSMUST00000133608.1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr6_+_51470339 0.88 ENSMUST00000094623.3
chromobox 3
chr9_-_99436749 0.86 ENSMUST00000122384.1
muscle and microspikes RAS
chr2_-_37359235 0.86 ENSMUST00000112940.1
phosducin-like
chr5_-_116288944 0.85 ENSMUST00000086483.3
coiled-coil domain containing 60
chr17_-_56874421 0.85 ENSMUST00000043062.4
acyl-CoA synthetase bubblegum family member 2
chr9_-_75409951 0.85 ENSMUST00000049355.10
mitogen-activated protein kinase 6
chr11_+_52232183 0.85 ENSMUST00000109072.1
S-phase kinase-associated protein 1A
chr7_+_92561141 0.83 ENSMUST00000032842.6
ENSMUST00000085017.4
coiled-coil domain containing 90B
chr1_+_153874335 0.83 ENSMUST00000055314.3
predicted gene 5531
chr11_-_93968242 0.82 ENSMUST00000107844.2
NME/NM23 nucleoside diphosphate kinase 1
chr4_+_155562348 0.82 ENSMUST00000030939.7
NAD kinase
chr10_+_28668360 0.82 ENSMUST00000060409.6
ENSMUST00000056097.4
ENSMUST00000105516.2
thymocyte selection associated
chr2_-_37359274 0.82 ENSMUST00000009174.8
phosducin-like
chr11_+_52232009 0.82 ENSMUST00000037324.5
ENSMUST00000166537.1
S-phase kinase-associated protein 1A
chr19_+_26748268 0.82 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr17_-_45595502 0.82 ENSMUST00000171081.1
ENSMUST00000172301.1
ENSMUST00000167332.1
ENSMUST00000170488.1
ENSMUST00000167195.1
ENSMUST00000064889.6
ENSMUST00000051574.6
ENSMUST00000164217.1
solute carrier family 29 (nucleoside transporters), member 1
chr13_+_24831661 0.82 ENSMUST00000038039.2
tyrosyl-DNA phosphodiesterase 2
chr2_-_103372725 0.81 ENSMUST00000139065.1
RIKEN cDNA A930006I01 gene
chrX_-_61185558 0.81 ENSMUST00000166381.1
cerebellar degeneration related antigen 1
chr8_-_64849818 0.81 ENSMUST00000034017.7
kelch-like 2, Mayven
chr5_+_29735940 0.80 ENSMUST00000114839.1
DnaJ (Hsp40) homolog, subfamily B, member 6
chr7_+_24257644 0.80 ENSMUST00000072713.6
zinc finger protein 108
chr15_-_82354280 0.80 ENSMUST00000023085.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 6 (B14)
chr10_-_100589205 0.80 ENSMUST00000054471.8
RIKEN cDNA 4930430F08 gene
chr3_+_81036360 0.79 ENSMUST00000029652.3
platelet-derived growth factor, C polypeptide
chr7_-_70366735 0.77 ENSMUST00000089565.5
nuclear receptor subfamily 2, group F, member 2
chr12_-_103631404 0.77 ENSMUST00000121625.1
ENSMUST00000044231.5
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr2_+_121456963 0.77 ENSMUST00000126764.1
huntingtin interacting protein K
chr13_+_41655697 0.77 ENSMUST00000067176.8
predicted gene 5082
chr7_+_136894598 0.75 ENSMUST00000081510.2
O-6-methylguanine-DNA methyltransferase
chr16_-_84835557 0.75 ENSMUST00000138279.1
ENSMUST00000023608.7
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr1_+_164249233 0.75 ENSMUST00000169394.1
solute carrier family 19 (thiamine transporter), member 2
chr1_+_91250482 0.75 ENSMUST00000171112.1
ubiquitin-conjugating enzyme E2F (putative)
chr4_-_88683912 0.74 ENSMUST00000105147.1
interferon alpha 2
chr5_-_139814025 0.74 ENSMUST00000146780.1
transmembrane protein 184a
chr14_-_79390666 0.73 ENSMUST00000022597.7
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chr7_-_126584578 0.73 ENSMUST00000150311.1
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr4_-_63861326 0.73 ENSMUST00000030047.2
tumor necrosis factor (ligand) superfamily, member 8
chr9_+_119402444 0.73 ENSMUST00000035093.8
ENSMUST00000165044.1
activin receptor IIB
chr17_+_53479212 0.73 ENSMUST00000017975.5
RAB5A, member RAS oncogene family
chr7_-_130519465 0.72 ENSMUST00000035458.7
ENSMUST00000033139.7
arginyltransferase 1
chr2_-_37359196 0.72 ENSMUST00000147703.1
phosducin-like
chr14_-_37135126 0.71 ENSMUST00000042564.9
growth hormone inducible transmembrane protein
chr16_+_88777829 0.71 ENSMUST00000009191.3
predicted gene 5965
chr15_+_87625214 0.71 ENSMUST00000068088.6
family with sequence similarity 19, member A5
chr5_-_139814231 0.71 ENSMUST00000044002.4
transmembrane protein 184a
chr10_+_127759721 0.70 ENSMUST00000073639.5
retinol dehydrogenase 1 (all trans)
chr5_+_29735991 0.70 ENSMUST00000012734.5
DnaJ (Hsp40) homolog, subfamily B, member 6
chr6_+_29853746 0.70 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
S-adenosylhomocysteine hydrolase-like 2
chr7_+_43975963 0.69 ENSMUST00000081399.3
kallikrein 1-related peptidase b9
chr6_+_48647224 0.69 ENSMUST00000078223.3
GTPase, IMAP family member 8
chr5_-_92675253 0.69 ENSMUST00000151180.1
ENSMUST00000150359.1
coiled-coil domain containing 158
chr6_+_88084473 0.68 ENSMUST00000032143.6
ribophorin I
chr15_-_99528017 0.68 ENSMUST00000023750.7
Fas apoptotic inhibitory molecule 2
chr11_-_54860564 0.67 ENSMUST00000144164.1
LYR motif containing 7
chrX_+_161717055 0.66 ENSMUST00000112338.1
retinoic acid induced 2
chr5_-_88676135 0.66 ENSMUST00000078945.5
G-rich RNA sequence binding factor 1
chr11_+_121146143 0.66 ENSMUST00000039088.8
ENSMUST00000155694.1
testis expressed gene 19.1
chr19_-_7039987 0.65 ENSMUST00000025918.7
stress-induced phosphoprotein 1
chr6_-_51469836 0.65 ENSMUST00000090002.7
heterogeneous nuclear ribonucleoprotein A2/B1
chr9_-_110989611 0.65 ENSMUST00000084922.5
receptor transporter protein 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsf4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0070342 brown fat cell proliferation(GO:0070342) regulation of brown fat cell proliferation(GO:0070347)
1.5 8.9 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
1.1 15.3 GO:0015747 urate transport(GO:0015747)
0.9 3.7 GO:0030026 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.8 2.4 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.7 5.9 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.5 3.8 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.5 1.6 GO:1904154 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.5 1.4 GO:0009804 coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.4 1.3 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.4 2.1 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.4 1.3 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.4 3.6 GO:0099640 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033) axo-dendritic protein transport(GO:0099640)
0.4 2.0 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.4 2.0 GO:0035063 nuclear speck organization(GO:0035063)
0.4 1.2 GO:0071350 interleukin-15-mediated signaling pathway(GO:0035723) cellular response to interleukin-15(GO:0071350)
0.4 2.7 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.4 1.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.4 1.5 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.4 2.5 GO:0016266 O-glycan processing(GO:0016266)
0.4 3.3 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.4 3.3 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.3 1.0 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.3 1.3 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.3 1.3 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.3 0.9 GO:0016237 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) suppression by virus of host autophagy(GO:0039521) negative regulation of sphingolipid biosynthesis involved in cellular sphingolipid homeostasis(GO:0090157)
0.3 2.1 GO:0015862 uridine transport(GO:0015862)
0.3 1.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.3 1.4 GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.3 1.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.3 0.8 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 1.0 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 0.7 GO:0016598 protein arginylation(GO:0016598)
0.2 1.4 GO:0018992 germ-line sex determination(GO:0018992)
0.2 0.7 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
0.2 0.9 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 0.7 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.2 1.5 GO:0006528 asparagine metabolic process(GO:0006528)
0.2 0.6 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 8.8 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.2 0.6 GO:0035973 aggrephagy(GO:0035973)
0.2 3.4 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.2 0.4 GO:0035927 RNA import into mitochondrion(GO:0035927)
0.2 1.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.6 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2 0.5 GO:0002296 T-helper 1 cell lineage commitment(GO:0002296)
0.2 1.1 GO:0001757 somite specification(GO:0001757)
0.2 0.5 GO:0036269 swimming behavior(GO:0036269)
0.2 0.6 GO:1903984 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.2 0.8 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.2 0.8 GO:0015888 thiamine transport(GO:0015888)
0.1 0.6 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 0.7 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.1 1.0 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.1 1.0 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.1 1.6 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.8 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 3.0 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.4 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.4 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 0.5 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.4 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.9 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1 0.6 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.5 GO:1900108 inner medullary collecting duct development(GO:0072061) negative regulation of nodal signaling pathway(GO:1900108)
0.1 1.0 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.1 1.3 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.1 1.7 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.4 GO:1900535 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.8 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 2.6 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.1 0.7 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.7 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.3 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.8 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1 1.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.3 GO:0015755 fructose transport(GO:0015755)
0.1 0.4 GO:0035962 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.1 0.8 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.9 GO:1904152 regulation of retrograde protein transport, ER to cytosol(GO:1904152)
0.1 0.4 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.1 0.4 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.1 0.7 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.1 0.3 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 3.5 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 0.6 GO:0051454 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.1 1.3 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.8 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 1.9 GO:0045116 protein neddylation(GO:0045116)
0.1 1.4 GO:0030238 male sex determination(GO:0030238)
0.1 0.3 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.1 0.7 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.1 1.4 GO:0010155 regulation of proton transport(GO:0010155)
0.1 0.4 GO:0090383 phagosome acidification(GO:0090383)
0.1 1.8 GO:0048240 sperm capacitation(GO:0048240)
0.1 1.7 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.1 0.9 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 3.6 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 0.5 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.1 GO:1901317 regulation of sperm motility(GO:1901317)
0.1 0.7 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 1.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.1 0.5 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.1 0.2 GO:2000812 response to rapamycin(GO:1901355) regulation of barbed-end actin filament capping(GO:2000812)
0.1 0.3 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.1 0.5 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.1 0.3 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.3 GO:0021564 vagus nerve development(GO:0021564)
0.1 0.6 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 2.2 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 1.4 GO:0035634 response to stilbenoid(GO:0035634)
0.1 3.1 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 0.3 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.2 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.1 0.6 GO:0042403 thyroid hormone metabolic process(GO:0042403)
0.0 0.4 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.0 0.2 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0 0.3 GO:0032627 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0 1.4 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.1 GO:0046439 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.2 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 2.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.3 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0 1.3 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 0.6 GO:0042407 cristae formation(GO:0042407)
0.0 0.6 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.5 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.6 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 0.7 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.5 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.7 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.1 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.5 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 2.8 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.7 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.3 GO:0009437 carnitine metabolic process(GO:0009437)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.2 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.7 GO:0021702 cerebellar Purkinje cell differentiation(GO:0021702)
0.0 0.1 GO:0033483 oxygen homeostasis(GO:0032364) gas homeostasis(GO:0033483)
0.0 0.1 GO:1902523 negative regulation of interleukin-18 production(GO:0032701) positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.0 1.1 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.6 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.2 GO:0044273 sulfur compound catabolic process(GO:0044273)
0.0 0.1 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 1.0 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.6 GO:0046839 phospholipid dephosphorylation(GO:0046839) phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.7 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 1.2 GO:0006749 glutathione metabolic process(GO:0006749)
0.0 0.3 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.4 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 0.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.1 GO:0097460 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.7 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 1.5 GO:0007286 spermatid development(GO:0007286)
0.0 0.2 GO:0003094 glomerular filtration(GO:0003094)
0.0 0.1 GO:1901673 regulation of mitotic spindle assembly(GO:1901673) negative regulation of cilium assembly(GO:1902018)
0.0 0.5 GO:0015909 long-chain fatty acid transport(GO:0015909)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 8.9 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.9 10.6 GO:0042612 MHC class I protein complex(GO:0042612)
0.3 1.6 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.3 2.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.2 3.5 GO:0097512 cardiac myofibril(GO:0097512)
0.2 0.7 GO:0098842 postsynaptic early endosome(GO:0098842)
0.2 1.4 GO:0000938 GARP complex(GO:0000938)
0.2 1.7 GO:0031467 Cul7-RING ubiquitin ligase complex(GO:0031467)
0.2 5.2 GO:0042101 T cell receptor complex(GO:0042101)
0.2 1.0 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 2.0 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.1 GO:1990357 terminal web(GO:1990357)
0.1 0.5 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.8 GO:0033503 HULC complex(GO:0033503)
0.1 0.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 1.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.0 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 0.6 GO:0061617 MICOS complex(GO:0061617)
0.1 0.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.6 GO:0071546 pi-body(GO:0071546)
0.1 0.6 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.2 GO:0060473 cortical granule(GO:0060473)
0.1 1.1 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.7 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.8 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.8 GO:0071564 npBAF complex(GO:0071564)
0.0 0.9 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.9 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.4 GO:0033391 chromatoid body(GO:0033391)
0.0 2.0 GO:0016235 aggresome(GO:0016235)
0.0 1.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.9 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 1.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.9 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.3 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 1.5 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0060091 kinocilium(GO:0060091)
0.0 5.1 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 2.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.4 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.4 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 1.1 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.9 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.4 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.5 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 2.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.8 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 3.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 5.2 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:1990712 dense body(GO:0097433) HFE-transferrin receptor complex(GO:1990712)
0.0 1.5 GO:0005604 basement membrane(GO:0005604)
0.0 0.1 GO:0097361 CIA complex(GO:0097361)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.0 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.4 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.6 GO:0000791 euchromatin(GO:0000791)
0.0 1.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
1.3 7.7 GO:0002135 CTP binding(GO:0002135)
1.0 15.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
1.0 2.9 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.9 3.7 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.8 10.6 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.7 2.1 GO:0032564 dATP binding(GO:0032564)
0.6 3.0 GO:0032767 copper-dependent protein binding(GO:0032767)
0.6 1.8 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.5 1.5 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.5 1.4 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.5 1.4 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.5 1.4 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.4 3.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.4 3.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 1.0 GO:0005118 sevenless binding(GO:0005118)
0.3 1.3 GO:0070573 metallodipeptidase activity(GO:0070573)
0.3 0.9 GO:0019779 Atg12 activating enzyme activity(GO:0019778) Atg8 activating enzyme activity(GO:0019779)
0.3 2.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.3 1.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.3 2.0 GO:0004046 aminoacylase activity(GO:0004046)
0.3 1.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.2 5.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.2 1.0 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.2 2.5 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.2 1.7 GO:0046790 virion binding(GO:0046790)
0.2 0.6 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.2 3.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 0.8 GO:0015403 thiamine uptake transmembrane transporter activity(GO:0015403)
0.2 0.9 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.2 2.0 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 1.1 GO:0051021 GDP-dissociation inhibitor binding(GO:0051021)
0.2 2.6 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 1.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 1.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.2 1.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.2 0.6 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 2.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.2 5.4 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.2 2.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.2 0.5 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.2 1.5 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 0.7 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.6 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.4 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.8 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 1.0 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.5 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 5.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 2.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 1.3 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.5 GO:0004142 diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.1 2.8 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.7 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 3.0 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.7 GO:0034711 inhibin binding(GO:0034711)
0.1 1.6 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.4 GO:0019215 intermediate filament binding(GO:0019215)
0.1 0.9 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.3 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241)
0.1 0.3 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 1.3 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.9 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 0.9 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.2 GO:0070002 glutamic-type peptidase activity(GO:0070002)
0.1 3.5 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.7 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 1.0 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 1.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.7 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.9 GO:0005537 mannose binding(GO:0005537)
0.0 2.8 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 4.2 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.8 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.9 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 1.3 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 1.8 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.6 GO:0043176 amine binding(GO:0043176)
0.0 1.0 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 1.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.4 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.2 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.7 GO:0016755 transferase activity, transferring amino-acyl groups(GO:0016755)
0.0 0.9 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 1.3 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 1.2 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 1.1 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.9 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.5 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 1.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 3.7 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 3.8 GO:0015293 symporter activity(GO:0015293)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.1 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.4 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.7 GO:0016706 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors(GO:0016706)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.6 GO:0051287 NAD binding(GO:0051287)
0.0 0.7 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.1 GO:0030957 Tat protein binding(GO:0030957)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 8.9 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 3.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 0.4 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 4.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 3.2 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 1.5 PID ARF 3PATHWAY Arf1 pathway
0.0 1.4 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 3.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 2.1 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.8 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.7 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 3.0 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.8 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.6 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 2.0 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.5 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 1.0 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.4 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.4 8.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.3 1.5 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.3 3.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.2 1.7 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.6 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 1.4 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 2.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 5.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.8 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 0.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 11.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.1 3.4 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 3.7 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.1 0.6 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 2.3 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 2.2 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 1.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 1.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.5 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 2.1 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.6 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.0 0.7 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.2 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.0 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling