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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hoxa4

Z-value: 1.92

Motif logo

Transcription factors associated with Hoxa4

Gene Symbol Gene ID Gene Info
ENSMUSG00000000942.10 homeobox A4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxa4mm10_v2_chr6_-_52191695_52191753-0.521.3e-03Click!

Activity profile of Hoxa4 motif

Sorted Z-values of Hoxa4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_61674094 10.89 ENSMUST00000098040.3
major urinary protein 18
chr4_-_60222580 10.05 ENSMUST00000095058.4
ENSMUST00000163931.1
major urinary protein 8
chr4_-_61835185 9.75 ENSMUST00000082287.2
major urinary protein 5
chr7_-_19699008 7.74 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
apolipoprotein E
chr9_-_50555170 6.51 ENSMUST00000119103.1
beta-carotene oxygenase 2
chr10_+_84756055 5.48 ENSMUST00000060397.6
regulatory factor X, 4 (influences HLA class II expression)
chr15_+_10249560 5.34 ENSMUST00000134410.1
prolactin receptor
chr2_+_70474923 5.16 ENSMUST00000100043.2
trans-acting transcription factor 5
chr10_+_87859481 4.94 ENSMUST00000121952.1
insulin-like growth factor 1
chr1_-_180193475 4.94 ENSMUST00000160482.1
ENSMUST00000170472.1
aarF domain containing kinase 3
chr4_+_144893077 4.75 ENSMUST00000154208.1
dehydrogenase/reductase (SDR family) member 3
chr1_-_180193653 4.69 ENSMUST00000159914.1
aarF domain containing kinase 3
chr7_+_51878967 4.54 ENSMUST00000051912.6
growth arrest specific 2
chr5_-_87092546 4.41 ENSMUST00000132667.1
ENSMUST00000145617.1
ENSMUST00000094649.4
UDP glucuronosyltransferase 2 family, polypeptide B36
chr10_+_87859255 4.35 ENSMUST00000105300.2
insulin-like growth factor 1
chr4_+_144892813 4.33 ENSMUST00000105744.1
ENSMUST00000171001.1
dehydrogenase/reductase (SDR family) member 3
chr4_+_144893127 4.29 ENSMUST00000142808.1
dehydrogenase/reductase (SDR family) member 3
chr7_+_51879041 4.17 ENSMUST00000107591.2
growth arrest specific 2
chr5_+_42067960 4.17 ENSMUST00000087332.4
predicted gene 16223
chr11_-_43836243 4.15 ENSMUST00000167574.1
adrenergic receptor, alpha 1b
chr10_+_87859062 4.14 ENSMUST00000095360.4
insulin-like growth factor 1
chr3_+_115080965 3.90 ENSMUST00000051309.8
olfactomedin 3
chr12_-_57546121 3.38 ENSMUST00000044380.6
forkhead box A1
chr18_+_37435602 3.23 ENSMUST00000055495.5
protocadherin beta 12
chr4_-_134372529 3.19 ENSMUST00000030643.2
exostoses (multiple)-like 1
chr16_+_37580137 3.10 ENSMUST00000160847.1
homogentisate 1, 2-dioxygenase
chr6_+_124916863 2.92 ENSMUST00000069553.2
RIKEN cDNA A230083G16 gene
chr13_+_58807884 2.81 ENSMUST00000079828.5
neurotrophic tyrosine kinase, receptor, type 2
chr2_+_20737306 2.80 ENSMUST00000114606.1
ENSMUST00000114608.1
enhancer trap locus 4
chr16_+_22857845 2.64 ENSMUST00000004574.7
ENSMUST00000178320.1
ENSMUST00000166487.2
DnaJ (Hsp40) homolog, subfamily B, member 11
chr6_+_124304646 2.59 ENSMUST00000112541.2
ENSMUST00000032234.2
CD163 antigen
chr2_-_5676046 2.56 ENSMUST00000114987.3
calcium/calmodulin-dependent protein kinase ID
chr1_+_74284930 2.55 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
paroxysmal nonkinesiogenic dyskinesia
chrM_+_5319 2.46 ENSMUST00000082402.1
mitochondrially encoded cytochrome c oxidase I
chr2_+_109917639 2.45 ENSMUST00000046548.7
ENSMUST00000111037.2
leucine-rich repeat-containing G protein-coupled receptor 4
chr11_-_116189542 2.41 ENSMUST00000148601.1
acyl-Coenzyme A oxidase 1, palmitoyl
chr9_-_65885024 2.38 ENSMUST00000122410.1
ENSMUST00000117083.1
thyroid hormone receptor interactor 4
chr11_+_94327984 2.33 ENSMUST00000107818.2
ENSMUST00000051221.6
ankyrin repeat domain 40
chr12_+_59129757 2.30 ENSMUST00000069430.8
ENSMUST00000177370.1
CTAGE family, member 5
chr2_-_77519565 2.21 ENSMUST00000111830.2
zinc finger protein 385B
chr10_+_53337686 2.19 ENSMUST00000046221.6
ENSMUST00000163319.1
phospholamban
chr6_+_43265582 2.17 ENSMUST00000031750.7
Rho guanine nucleotide exchange factor (GEF) 5
chr10_-_24101951 2.17 ENSMUST00000170267.1
trace amine-associated receptor 8C
chr17_-_34862122 2.14 ENSMUST00000154526.1
complement factor B
chr13_+_89540636 2.14 ENSMUST00000022108.7
hyaluronan and proteoglycan link protein 1
chr6_+_63255971 2.13 ENSMUST00000159561.1
ENSMUST00000095852.3
glutamate receptor, ionotropic, delta 2
chr11_+_94328242 2.11 ENSMUST00000021227.5
ankyrin repeat domain 40
chr7_-_34654342 2.08 ENSMUST00000108069.1
potassium channel tetramerisation domain containing 15
chr17_+_45734506 2.06 ENSMUST00000180558.1
RIKEN cDNA F630040K05 gene
chr12_+_59129720 2.00 ENSMUST00000175912.1
ENSMUST00000176892.1
CTAGE family, member 5
chr18_+_58659443 1.99 ENSMUST00000025503.8
isochorismatase domain containing 1
chr19_+_31868754 1.90 ENSMUST00000075838.5
APOBEC1 complementation factor
chr6_+_21986887 1.88 ENSMUST00000151315.1
cadherin-like and PC-esterase domain containing 1
chr11_-_49114874 1.86 ENSMUST00000109201.1
olfactory receptor 1396
chr3_+_89459118 1.84 ENSMUST00000029564.5
phosphomevalonate kinase
chr10_+_4611971 1.84 ENSMUST00000105590.1
ENSMUST00000067086.7
estrogen receptor 1 (alpha)
chr5_+_139543889 1.83 ENSMUST00000174792.1
ENSMUST00000031523.8
UNC homeobox
chr1_+_165788681 1.76 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
CD247 antigen
chr1_+_132298606 1.72 ENSMUST00000046071.4
kelch domain containing 8A
chr17_+_24850515 1.72 ENSMUST00000154363.1
ENSMUST00000169200.1
hydroxyacyl glutathione hydrolase
chr13_-_55362782 1.71 ENSMUST00000021940.7
lectin, mannose-binding 2
chr17_+_24850654 1.69 ENSMUST00000130989.1
ENSMUST00000024974.9
hydroxyacyl glutathione hydrolase
chr12_-_56535047 1.67 ENSMUST00000178477.2
NK2 homeobox 1
chr5_+_30814722 1.66 ENSMUST00000114724.1
microtubule-associated protein, RP/EB family, member 3
chr7_+_76411062 1.65 ENSMUST00000026854.3
ENSMUST00000107442.2
ATP/GTP binding protein-like 1
chr10_-_127121125 1.61 ENSMUST00000164259.1
ENSMUST00000080975.4
amplified in osteosarcoma
chr11_-_21572193 1.59 ENSMUST00000102874.4
malate dehydrogenase 1, NAD (soluble)
chr5_-_84417359 1.59 ENSMUST00000113401.1
Eph receptor A5
chr19_-_28967794 1.58 ENSMUST00000162110.1
RIKEN cDNA 4430402I18 gene
chr18_+_37447641 1.58 ENSMUST00000052387.3
protocadherin beta 14
chr8_-_67974567 1.58 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
pleckstrin and Sec7 domain containing 3
chr16_-_36990449 1.57 ENSMUST00000075869.6
F-box protein 40
chr12_+_55598917 1.56 ENSMUST00000051857.3
insulinoma-associated 2
chr15_+_32920723 1.55 ENSMUST00000022871.5
syndecan 2
chr6_+_54040078 1.54 ENSMUST00000127323.2
chimerin (chimaerin) 2
chr2_+_170731807 1.53 ENSMUST00000029075.4
docking protein 5
chr2_-_119547194 1.51 ENSMUST00000133668.1
exonuclease 3'-5' domain containing 1
chr7_+_131966446 1.50 ENSMUST00000045840.4
G protein-coupled receptor 26
chr1_+_165788746 1.49 ENSMUST00000161559.2
CD247 antigen
chr1_-_138848576 1.44 ENSMUST00000112030.2
LIM homeobox protein 9
chr3_-_32491969 1.43 ENSMUST00000164954.1
potassium large conductance calcium-activated channel, subfamily M, beta member 3
chr8_+_22624019 1.42 ENSMUST00000033936.6
dickkopf homolog 4 (Xenopus laevis)
chr10_+_127420334 1.42 ENSMUST00000171434.1
R3H domain containing 2
chr2_+_70563435 1.39 ENSMUST00000123330.1
glutamate decarboxylase 1
chr14_-_30353468 1.36 ENSMUST00000112249.1
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr6_-_138426735 1.35 ENSMUST00000162932.1
LIM domain only 3
chr3_+_86070915 1.35 ENSMUST00000182666.1
SH3 domain protein D19
chr8_+_47713266 1.33 ENSMUST00000180928.1
RIKEN cDNA E030037K01 gene
chr1_-_67038824 1.33 ENSMUST00000119559.1
ENSMUST00000149996.1
ENSMUST00000027149.5
ENSMUST00000113979.3
LanC (bacterial lantibiotic synthetase component C)-like 1
chrM_+_10167 1.33 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr2_+_147187424 1.33 ENSMUST00000144411.1
RIKEN cDNA 6430503K07 gene
chr5_-_146220901 1.32 ENSMUST00000169407.2
ENSMUST00000161331.1
ENSMUST00000159074.2
ENSMUST00000067837.3
ring finger protein (C3H2C3 type) 6
chr9_-_29412204 1.31 ENSMUST00000115237.1
neurotrimin
chr19_+_8840519 1.30 ENSMUST00000086058.6
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chrX_+_7579666 1.27 ENSMUST00000115740.1
ENSMUST00000115739.1
forkhead box P3
chr6_+_8949670 1.26 ENSMUST00000060369.3
neurexophilin 1
chr11_-_99337930 1.24 ENSMUST00000100482.2
keratin 26
chrX_+_48623737 1.24 ENSMUST00000114936.1
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr1_-_5070281 1.22 ENSMUST00000147158.1
ENSMUST00000118000.1
regulator of G-protein signaling 20
chr14_-_50897456 1.19 ENSMUST00000170855.1
RIKEN cDNA A930018M24 gene
chr5_+_105824511 1.14 ENSMUST00000055994.3
RIKEN cDNA D830014E11 gene
chr3_-_88177671 1.12 ENSMUST00000181837.1
RIKEN cDNA 1700113A16 gene
chr10_+_39612934 1.12 ENSMUST00000019987.6
TRAF3 interacting protein 2
chr5_+_115235836 1.11 ENSMUST00000081497.6
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr12_+_10390756 1.11 ENSMUST00000020947.5
retinol dehydrogenase 14 (all-trans and 9-cis)
chr19_+_24875679 1.09 ENSMUST00000073080.5
predicted gene 10053
chr3_+_5218546 1.08 ENSMUST00000026284.6
zinc finger homeodomain 4
chr17_+_39846958 1.08 ENSMUST00000182010.1
predicted gene, 26924
chr18_-_61014199 1.05 ENSMUST00000025520.8
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr1_-_190170671 1.02 ENSMUST00000175916.1
prospero-related homeobox 1
chr13_+_63015167 1.02 ENSMUST00000021911.8
RIKEN cDNA 2010111I01 gene
chrX_-_106603677 1.02 ENSMUST00000113480.1
cysteinyl leukotriene receptor 1
chr9_+_77636494 1.00 ENSMUST00000057781.7
kelch-like 31
chr5_-_32133045 1.00 ENSMUST00000031308.6
predicted gene 10463
chr4_+_99295900 0.99 ENSMUST00000094955.1
predicted gene 12689
chr15_-_37458523 0.99 ENSMUST00000116445.2
neurocalcin delta
chr4_-_116053825 0.98 ENSMUST00000030475.1
NOL1/NOP2/Sun domain family, member 4
chr19_-_20954202 0.97 ENSMUST00000039500.3
transmembrane channel-like gene family 1
chr8_+_46986913 0.97 ENSMUST00000039840.7
ENSMUST00000119686.1
ectonucleotide pyrophosphatase/phosphodiesterase 6
chr1_-_93478785 0.97 ENSMUST00000170883.1
high density lipoprotein (HDL) binding protein
chr8_-_45294854 0.97 ENSMUST00000116473.2
kallikrein B, plasma 1
chr8_-_84937347 0.96 ENSMUST00000109741.2
ENSMUST00000119820.1
microtubule associated serine/threonine kinase 1
chr19_+_11965817 0.95 ENSMUST00000025590.9
oxysterol binding protein
chr2_+_83956398 0.95 ENSMUST00000178325.1
predicted gene 13698
chr15_+_55307743 0.92 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
collagen, type XIV, alpha 1
chr7_-_122101735 0.91 ENSMUST00000139456.1
ENSMUST00000106471.2
ENSMUST00000123296.1
ENSMUST00000033157.3
NADH dehydrogenase (ubiquinone) 1, alpha/beta subcomplex, 1
chr16_-_64786321 0.90 ENSMUST00000052588.4
zinc finger protein 654
chr11_+_67200137 0.90 ENSMUST00000129018.1
myosin, heavy polypeptide 1, skeletal muscle, adult
chr9_-_77399308 0.89 ENSMUST00000183878.1
RP23-264N13.2
chr11_-_99374895 0.89 ENSMUST00000006963.2
keratin 28
chr16_-_22857514 0.88 ENSMUST00000004576.6
TBCC domain containing 1
chr6_+_97210689 0.87 ENSMUST00000044681.6
ADP-ribosylation factor-like 6 interacting protein 5
chr13_+_63014934 0.86 ENSMUST00000091560.4
RIKEN cDNA 2010111I01 gene
chr13_+_38204928 0.85 ENSMUST00000091641.5
ENSMUST00000178564.1
small nuclear ribonucleoprotein 48 (U11/U12)
chr17_+_24470393 0.85 ENSMUST00000053024.6
phosphoglycolate phosphatase
chr10_+_127421124 0.85 ENSMUST00000170336.1
R3H domain containing 2
chr5_-_87699414 0.85 ENSMUST00000082370.5
casein beta
chr15_-_99820072 0.83 ENSMUST00000109024.2
LIM domain and actin binding 1
chr6_+_21986438 0.82 ENSMUST00000115382.1
cadherin-like and PC-esterase domain containing 1
chr6_-_77979515 0.82 ENSMUST00000159626.1
ENSMUST00000075340.5
ENSMUST00000162273.1
catenin (cadherin associated protein), alpha 2
chr4_+_11579647 0.81 ENSMUST00000180239.1
fibrinogen silencer binding protein
chr3_+_93442330 0.81 ENSMUST00000064257.5
trichohyalin
chr18_-_31949571 0.81 ENSMUST00000064016.5
G protein-coupled receptor 17
chr4_+_150237694 0.81 ENSMUST00000141931.1
enolase 1, alpha non-neuron
chrX_-_112698642 0.81 ENSMUST00000039887.3
premature ovarian failure 1B
chr8_-_67515606 0.80 ENSMUST00000032981.5
predicted pseudogene 9755
chr16_-_50432340 0.79 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
bobby sox homolog (Drosophila)
chr3_+_5218516 0.79 ENSMUST00000175866.1
zinc finger homeodomain 4
chr19_-_57197377 0.78 ENSMUST00000111546.1
actin-binding LIM protein 1
chr14_+_46832127 0.77 ENSMUST00000068532.8
cell growth regulator with ring finger domain 1
chr5_-_137531204 0.76 ENSMUST00000150063.2
guanine nucleotide binding protein (G protein), beta 2
chr3_+_41564880 0.73 ENSMUST00000168086.1
PHD finger protein 17
chr15_+_28203726 0.71 ENSMUST00000067048.6
dynein, axonemal, heavy chain 5
chr3_-_80802789 0.70 ENSMUST00000107745.1
ENSMUST00000075316.4
glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr18_-_20114767 0.69 ENSMUST00000038710.5
desmocollin 1
chr6_-_73138947 0.69 ENSMUST00000114038.1
dynein, axonemal, heavy chain 6
chr19_-_57197435 0.68 ENSMUST00000111550.1
actin-binding LIM protein 1
chr10_+_24076500 0.68 ENSMUST00000051133.5
trace amine-associated receptor 8A
chr10_+_127420867 0.66 ENSMUST00000064793.6
R3H domain containing 2
chr3_+_94837702 0.64 ENSMUST00000107266.1
ENSMUST00000042402.5
ENSMUST00000107269.1
pogo transposable element with ZNF domain
chr18_+_37489465 0.64 ENSMUST00000055949.2
protocadherin beta 18
chr7_-_120145286 0.64 ENSMUST00000033207.4
zona pellucida glycoprotein 2
chr10_+_18469958 0.64 ENSMUST00000162891.1
ENSMUST00000100054.3
NHS-like 1
chr11_-_100041547 0.63 ENSMUST00000056362.2
keratin 34
chr6_+_29468068 0.63 ENSMUST00000143101.1
ATPase, H+ transporting, lysosomal V1 subunit F
chr5_-_137314175 0.62 ENSMUST00000024119.9
thyroid hormone receptor interactor 6
chrX_+_150589907 0.62 ENSMUST00000080884.4
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr1_-_130729249 0.62 ENSMUST00000171479.1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr9_+_75775355 0.61 ENSMUST00000012281.7
bone morphogenetic protein 5
chr2_+_174327747 0.59 ENSMUST00000087871.4
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr2_-_116065798 0.58 ENSMUST00000110907.1
ENSMUST00000110908.2
Meis homeobox 2
chrX_+_136822671 0.58 ENSMUST00000033800.6
proteolipid protein (myelin) 1
chr7_-_35056467 0.57 ENSMUST00000130491.1
CCAAT/enhancer binding protein (C/EBP), gamma
chr16_-_76373827 0.56 ENSMUST00000121927.1
nuclear receptor interacting protein 1
chr3_+_94837533 0.56 ENSMUST00000107270.2
pogo transposable element with ZNF domain
chr12_+_55384222 0.55 ENSMUST00000163070.1
proteasome (prosome, macropain) subunit, alpha type 6
chr19_-_38224096 0.55 ENSMUST00000067167.5
FRA10AC1 homolog (human)
chr1_-_92518515 0.55 ENSMUST00000062353.4
olfactory receptor 1414
chr16_+_17331371 0.54 ENSMUST00000023450.6
ENSMUST00000161034.1
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr1_+_180111339 0.53 ENSMUST00000145181.1
CDC42 binding protein kinase alpha
chr9_-_37669170 0.52 ENSMUST00000011262.2
pannexin 3
chr18_-_79109391 0.52 ENSMUST00000025430.8
ENSMUST00000161465.2
SET binding protein 1
chr18_+_37355271 0.52 ENSMUST00000051163.1
protocadherin beta 8
chr17_-_43667015 0.52 ENSMUST00000024705.4
solute carrier family 25, member 27
chr15_-_37459327 0.51 ENSMUST00000119730.1
ENSMUST00000120746.1
neurocalcin delta
chr1_-_110977366 0.51 ENSMUST00000094626.3
cadherin 19, type 2
chr10_+_127421208 0.50 ENSMUST00000168780.1
R3H domain containing 2
chr1_-_163313661 0.50 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
paired related homeobox 1
chr2_-_93849679 0.50 ENSMUST00000068513.4
ENSMUST00000041593.8
ENSMUST00000130077.1
1-aminocyclopropane-1-carboxylate synthase (non-functional)
chr11_-_33203588 0.50 ENSMUST00000037746.6
T cell leukemia, homeobox 3
chr3_-_146781351 0.49 ENSMUST00000005164.7
protein kinase, cAMP dependent, catalytic, beta
chr5_-_122614445 0.49 ENSMUST00000127220.1
ENSMUST00000031426.7
intraflagellar transport 81
chrX_-_48513518 0.49 ENSMUST00000114945.2
ENSMUST00000037349.7
apoptosis-inducing factor, mitochondrion-associated 1
chr15_-_82912134 0.49 ENSMUST00000048966.5
ENSMUST00000109510.2
transcription factor 20
chr6_+_106118924 0.49 ENSMUST00000079416.5
contactin 4
chr6_+_29467718 0.47 ENSMUST00000004396.6
ATPase, H+ transporting, lysosomal V1 subunit F
chr12_-_31713873 0.47 ENSMUST00000057783.4
ENSMUST00000174480.2
ENSMUST00000176710.1
G protein-coupled receptor 22
chr3_+_5218589 0.47 ENSMUST00000177488.1
zinc finger homeodomain 4
chr5_-_137530990 0.45 ENSMUST00000132525.1
guanine nucleotide binding protein (G protein), beta 2
chr8_+_106059562 0.45 ENSMUST00000109308.1
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
2.2 13.4 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
1.7 3.4 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.4 4.1 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982)
1.1 5.5 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.9 5.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.8 13.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.8 2.4 GO:0061289 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.7 6.5 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.6 3.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.6 6.0 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.6 1.7 GO:0021759 globus pallidus development(GO:0021759)
0.5 2.2 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.5 1.8 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.4 1.3 GO:0002465 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment(GO:0002362) peripheral T cell tolerance induction(GO:0002458) peripheral tolerance induction(GO:0002465) negative regulation of histone deacetylation(GO:0031064) negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.4 1.7 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.4 2.4 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.4 2.8 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.3 1.0 GO:0002194 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.3 1.4 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 1.8 GO:0060011 Sertoli cell proliferation(GO:0060011) prostate epithelial cord elongation(GO:0060523)
0.3 1.4 GO:0035262 gonad morphogenesis(GO:0035262)
0.3 2.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.3 1.6 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.3 1.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.3 2.0 GO:0009249 protein lipoylation(GO:0009249)
0.2 1.0 GO:0060005 vestibular reflex(GO:0060005)
0.2 1.6 GO:0006621 protein retention in ER lumen(GO:0006621)
0.2 1.6 GO:0006108 malate metabolic process(GO:0006108)
0.2 1.3 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.2 2.2 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.2 0.9 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.2 0.6 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.2 1.8 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.2 1.4 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.2 1.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.2 1.0 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.2 1.9 GO:0016554 cytidine to uridine editing(GO:0016554)
0.2 0.9 GO:0051684 maintenance of centrosome location(GO:0051661) maintenance of Golgi location(GO:0051684)
0.2 2.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 1.0 GO:0042256 mature ribosome assembly(GO:0042256)
0.2 0.6 GO:0021502 neural fold elevation formation(GO:0021502)
0.1 2.9 GO:0060134 prepulse inhibition(GO:0060134)
0.1 0.6 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.8 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 2.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 2.6 GO:0016556 mRNA modification(GO:0016556)
0.1 1.4 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 1.0 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.4 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.1 0.6 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.3 GO:0046166 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.3 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.1 1.2 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 1.6 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.1 0.4 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 0.6 GO:0060468 prevention of polyspermy(GO:0060468)
0.1 0.6 GO:0097475 motor neuron migration(GO:0097475)
0.1 1.5 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.1 0.3 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.3 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.1 0.2 GO:0030573 bile acid catabolic process(GO:0030573)
0.1 0.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 1.2 GO:0051382 kinetochore assembly(GO:0051382)
0.1 0.1 GO:0060197 cloaca development(GO:0035844) cloacal septation(GO:0060197)
0.1 3.9 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.1 1.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.1 0.4 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.5 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 1.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.4 GO:0072093 ureteric bud invasion(GO:0072092) metanephric renal vesicle formation(GO:0072093)
0.1 1.9 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.1 3.2 GO:0070207 protein homotrimerization(GO:0070207)
0.1 1.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 0.6 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.1 0.4 GO:0035166 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) post-embryonic hemopoiesis(GO:0035166)
0.1 1.1 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.8 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.3 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.1 0.2 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.1 0.5 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.1 1.6 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 1.3 GO:0050995 negative regulation of lipid catabolic process(GO:0050995)
0.1 2.4 GO:0030520 intracellular estrogen receptor signaling pathway(GO:0030520)
0.1 2.6 GO:0006953 acute-phase response(GO:0006953)
0.1 0.2 GO:0002674 negative regulation of acute inflammatory response(GO:0002674)
0.1 1.0 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.8 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.7 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 2.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.1 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.5 GO:0048664 neuron fate determination(GO:0048664)
0.0 1.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 6.0 GO:0007050 cell cycle arrest(GO:0007050)
0.0 0.1 GO:0010841 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841)
0.0 1.0 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 1.1 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.5 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.4 GO:0071380 cellular response to prostaglandin E stimulus(GO:0071380)
0.0 1.0 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.9 GO:0061050 regulation of cell growth involved in cardiac muscle cell development(GO:0061050)
0.0 3.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.4 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 1.1 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.4 GO:0045109 intermediate filament organization(GO:0045109)
0.0 2.7 GO:0048706 embryonic skeletal system development(GO:0048706)
0.0 1.5 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.9 GO:2000242 negative regulation of reproductive process(GO:2000242)
0.0 0.8 GO:0070830 bicellular tight junction assembly(GO:0070830)
0.0 0.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 1.4 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0 0.4 GO:0007274 neuromuscular synaptic transmission(GO:0007274)
0.0 0.7 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.0 0.7 GO:0003341 cilium movement(GO:0003341)
0.0 3.2 GO:0043413 protein glycosylation(GO:0006486) macromolecule glycosylation(GO:0043413)
0.0 0.7 GO:0008542 visual learning(GO:0008542)
0.0 0.3 GO:0002053 positive regulation of mesenchymal cell proliferation(GO:0002053)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 7.7 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
1.5 13.4 GO:0042567 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) insulin-like growth factor ternary complex(GO:0042567)
0.4 3.2 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.3 1.9 GO:0045293 mRNA editing complex(GO:0045293)
0.3 1.5 GO:1990923 PET complex(GO:1990923)
0.3 1.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 0.6 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.2 1.6 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.2 2.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.2 1.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.4 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.1 2.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 1.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 4.4 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 2.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 4.2 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.4 GO:1990130 Iml1 complex(GO:1990130) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.0 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 0.7 GO:0036156 inner dynein arm(GO:0036156)
0.1 2.1 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.1 0.3 GO:0032437 cuticular plate(GO:0032437)
0.1 0.6 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.5 GO:0030057 desmosome(GO:0030057)
0.0 0.7 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.9 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.9 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 1.0 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.4 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 3.6 GO:0030315 T-tubule(GO:0030315)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 2.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.4 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 2.2 GO:0070469 respiratory chain(GO:0070469)
0.0 1.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.9 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 2.4 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 3.8 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 3.8 GO:0042641 actomyosin(GO:0042641)
0.0 1.7 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.5 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0005916 fascia adherens(GO:0005916)
0.0 3.8 GO:0001650 fibrillar center(GO:0001650)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 2.0 GO:0005882 intermediate filament(GO:0005882)
0.0 1.0 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 2.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.2 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0005921 gap junction(GO:0005921)
0.0 1.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 7.7 GO:0046911 metal chelating activity(GO:0046911)
1.9 13.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
1.1 5.3 GO:0004925 prolactin receptor activity(GO:0004925)
1.1 3.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
1.0 4.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.7 6.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.6 1.8 GO:0038052 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.5 1.6 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.5 2.8 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.4 2.4 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.4 1.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.4 2.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.4 9.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.3 9.3 GO:0005550 pheromone binding(GO:0005550)
0.3 1.0 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.3 2.7 GO:0001594 trace-amine receptor activity(GO:0001594)
0.3 1.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.2 0.9 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.2 0.6 GO:0032190 acrosin binding(GO:0032190)
0.2 1.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 1.4 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.2 5.8 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 1.2 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 2.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 4.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 1.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.1 0.4 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.1 0.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.7 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.1 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1 1.0 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 1.3 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.5 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 2.0 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1 1.0 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.1 0.4 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 2.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 2.5 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 3.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.1 1.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.7 GO:0005537 mannose binding(GO:0005537)
0.1 0.8 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 0.8 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.4 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 1.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.1 0.4 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.1 2.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 1.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 1.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 1.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.5 GO:0005158 insulin receptor binding(GO:0005158)
0.0 3.2 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 1.1 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.6 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.0 GO:0015248 sterol transporter activity(GO:0015248)
0.0 1.8 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.6 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 1.3 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.3 GO:0051378 serotonin binding(GO:0051378)
0.0 2.6 GO:0051082 unfolded protein binding(GO:0051082)
0.0 1.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 7.7 GO:0008017 microtubule binding(GO:0008017)
0.0 2.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.3 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.5 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.6 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.8 GO:0005549 odorant binding(GO:0005549)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.2 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 15.3 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.2 12.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 8.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 5.3 PID ERBB4 PATHWAY ErbB4 signaling events
0.1 4.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 4.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 4.8 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.1 3.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 4.4 PID SHP2 PATHWAY SHP2 signaling
0.1 1.2 ST G ALPHA I PATHWAY G alpha i Pathway
0.1 1.6 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 6.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.5 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 3.9 PID P73PATHWAY p73 transcription factor network
0.1 2.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.0 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.7 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.5 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 2.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.7 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.8 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 1.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.8 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.7 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 3.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.3 8.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.3 5.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 2.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 2.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 4.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 2.4 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.1 3.9 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.1 1.5 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 2.1 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.8 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 1.1 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.1 1.4 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.8 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 1.0 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 1.1 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.0 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 1.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.4 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 3.1 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 2.1 REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE Genes involved in NGF signalling via TRKA from the plasma membrane
0.0 0.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation