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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hoxa10

Z-value: 1.51

Motif logo

Transcription factors associated with Hoxa10

Gene Symbol Gene ID Gene Info
ENSMUSG00000000938.11 homeobox A10

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxa10mm10_v2_chr6_-_52234902_52234960-0.391.9e-02Click!

Activity profile of Hoxa10 motif

Sorted Z-values of Hoxa10 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_102658640 6.07 ENSMUST00000080210.3
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr2_+_68117713 4.76 ENSMUST00000112346.2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr7_-_14446651 4.71 ENSMUST00000125941.1
RIKEN cDNA 2810007J24 gene
chr5_-_87092546 4.16 ENSMUST00000132667.1
ENSMUST00000145617.1
ENSMUST00000094649.4
UDP glucuronosyltransferase 2 family, polypeptide B36
chr5_+_146079254 4.15 ENSMUST00000035571.8
cytochrome P450, family 3, subfamily a, polypeptide 59
chr13_-_22219820 4.05 ENSMUST00000057516.1
vomeronasal 1 receptor 193
chr5_-_87091150 3.94 ENSMUST00000154455.1
UDP glucuronosyltransferase 2 family, polypeptide B36
chr13_-_41847482 3.65 ENSMUST00000072012.3
androgen dependent TFPI regulating protein
chr13_-_41847599 3.40 ENSMUST00000179758.1
androgen dependent TFPI regulating protein
chr2_-_164638789 2.99 ENSMUST00000109336.1
WAP four-disulfide core domain 16
chr1_-_140183283 2.97 ENSMUST00000111977.1
complement component factor h
chr9_+_55326913 2.96 ENSMUST00000085754.3
ENSMUST00000034862.4
expressed sequence AI118078
chr1_+_167618246 2.87 ENSMUST00000111380.1
retinoid X receptor gamma
chr1_+_74713551 2.64 ENSMUST00000027356.5
cytochrome P450, family 27, subfamily a, polypeptide 1
chr19_+_4711153 2.62 ENSMUST00000008991.6
spectrin beta, non-erythrocytic 2
chr7_+_51880312 2.61 ENSMUST00000145049.1
growth arrest specific 2
chr19_+_30232921 2.58 ENSMUST00000025797.5
mannose-binding lectin (protein C) 2
chr1_-_140183404 2.50 ENSMUST00000066859.6
ENSMUST00000111976.2
complement component factor h
chr16_+_56477838 2.40 ENSMUST00000048471.7
ENSMUST00000096013.3
ENSMUST00000096012.3
ENSMUST00000171000.1
ABI gene family, member 3 (NESH) binding protein
chr17_+_36958623 2.31 ENSMUST00000173814.1
Znrd1 antisense
chr17_+_36958571 2.31 ENSMUST00000040177.6
Znrd1 antisense
chr15_+_4727265 2.19 ENSMUST00000162350.1
complement component 6
chr4_+_42629719 2.17 ENSMUST00000166898.2
predicted gene 2564
chr4_-_119383732 2.11 ENSMUST00000044781.2
ENSMUST00000084307.3
coiled-coil domain containing 30
chr6_-_83677807 2.10 ENSMUST00000037882.6
CD207 antigen
chr3_+_129836729 2.00 ENSMUST00000077918.5
complement component factor i
chr14_-_122913751 1.96 ENSMUST00000160401.1
gamma-glutamylamine cyclotransferase
chr6_+_59208870 1.90 ENSMUST00000062626.3
tigger transposable element derived 2
chrX_+_10252361 1.89 ENSMUST00000115528.2
ornithine transcarbamylase
chr2_+_91255954 1.88 ENSMUST00000134699.1
protein kinase C and casein kinase substrate in neurons 3
chr18_-_12860197 1.86 ENSMUST00000124570.1
oxysterol binding protein-like 1A
chrX_+_10252305 1.81 ENSMUST00000049910.6
ornithine transcarbamylase
chr9_-_51328898 1.79 ENSMUST00000039959.4
RIKEN cDNA 1810046K07 gene
chr1_+_127729405 1.78 ENSMUST00000038006.6
amino carboxymuconate semialdehyde decarboxylase
chr4_-_109202217 1.75 ENSMUST00000160774.1
ENSMUST00000030288.7
ENSMUST00000162787.2
oxysterol binding protein-like 9
chr7_-_73537621 1.74 ENSMUST00000172704.1
chromodomain helicase DNA binding protein 2
chr18_-_3309723 1.70 ENSMUST00000136961.1
ENSMUST00000152108.1
cAMP responsive element modulator
chr18_-_3281712 1.68 ENSMUST00000182204.1
ENSMUST00000154705.1
ENSMUST00000182833.1
ENSMUST00000151084.1
cAMP responsive element modulator
chr13_+_23839401 1.68 ENSMUST00000039721.7
ENSMUST00000166467.1
solute carrier family 17 (sodium phosphate), member 3
chr2_+_91256144 1.67 ENSMUST00000154959.1
ENSMUST00000059566.4
protein kinase C and casein kinase substrate in neurons 3
chr15_-_3303521 1.63 ENSMUST00000165386.1
coiled-coil domain containing 152
chr13_+_23839445 1.59 ENSMUST00000091698.4
ENSMUST00000110422.1
solute carrier family 17 (sodium phosphate), member 3
chr6_+_54264839 1.58 ENSMUST00000146114.1
chimerin (chimaerin) 2
chr2_+_83812567 1.55 ENSMUST00000051454.3
family with sequence similarity 171, member B
chr5_-_123666682 1.53 ENSMUST00000149410.1
CAP-GLY domain containing linker protein 1
chr7_+_45277502 1.53 ENSMUST00000176276.1
RIKEN cDNA 1700039E15 gene
chr15_+_3270767 1.43 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
selenoprotein P, plasma, 1
chr3_+_94398517 1.41 ENSMUST00000050975.3
leucine rich repeat and Ig domain containing 4
chr18_-_39487096 1.38 ENSMUST00000097592.2
ENSMUST00000115571.1
nuclear receptor subfamily 3, group C, member 1
chr13_-_90089060 1.37 ENSMUST00000161396.1
X-ray repair complementing defective repair in Chinese hamster cells 4
chr9_+_54538984 1.33 ENSMUST00000060242.5
ENSMUST00000118413.1
SH2 domain containing 7
chr19_+_31868754 1.31 ENSMUST00000075838.5
APOBEC1 complementation factor
chr19_+_29925107 1.30 ENSMUST00000120388.2
ENSMUST00000144528.1
ENSMUST00000177518.1
interleukin 33
chr2_+_15049395 1.29 ENSMUST00000017562.6
ADP-ribosylation factor-like 5B
chr3_+_132634725 1.29 ENSMUST00000163241.1
predicted gene 5549
chr18_+_33464163 1.27 ENSMUST00000097634.3
predicted gene 10549
chrM_+_14138 1.27 ENSMUST00000082421.1
mitochondrially encoded cytochrome b
chr18_-_3281752 1.26 ENSMUST00000140332.1
ENSMUST00000147138.1
cAMP responsive element modulator
chrM_+_3906 1.26 ENSMUST00000082396.1
mitochondrially encoded NADH dehydrogenase 2
chrM_-_14060 1.23 ENSMUST00000082419.1
mitochondrially encoded NADH dehydrogenase 6
chr15_-_54919961 1.21 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr18_-_3309858 1.19 ENSMUST00000144496.1
ENSMUST00000154715.1
cAMP responsive element modulator
chr2_-_77519565 1.18 ENSMUST00000111830.2
zinc finger protein 385B
chr17_-_6079693 1.17 ENSMUST00000024570.5
ENSMUST00000097432.3
serine active site containing 1
chr4_-_138326234 1.16 ENSMUST00000105817.3
ENSMUST00000030536.6
PTEN induced putative kinase 1
chr9_-_50739365 1.14 ENSMUST00000117093.1
ENSMUST00000121634.1
DIX domain containing 1
chr15_-_54920115 1.13 ENSMUST00000171545.1
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr2_-_51149100 1.12 ENSMUST00000154545.1
ENSMUST00000017288.2
Rho family GTPase 3
chr9_+_122888471 1.11 ENSMUST00000063980.6
zinc finger with KRAB and SCAN domains 7
chr6_-_142278836 1.07 ENSMUST00000111825.3
solute carrier organic anion transporter family, member 1a5
chr10_-_56228636 1.07 ENSMUST00000099739.3
TBC1 domain family, member 32
chr2_+_177508570 1.07 ENSMUST00000108940.2
predicted gene 14403
chr13_-_74376566 1.06 ENSMUST00000091481.2
zinc finger protein 72
chr17_+_88626549 1.03 ENSMUST00000163588.1
ENSMUST00000064035.6
stonin 1
chr8_-_41054771 0.98 ENSMUST00000093534.4
mitochondrial tumor suppressor 1
chr16_-_35871544 0.97 ENSMUST00000042665.8
poly (ADP-ribose) polymerase family, member 14
chr4_+_141746672 0.95 ENSMUST00000038161.4
agmatine ureohydrolase (agmatinase)
chr17_+_88626569 0.92 ENSMUST00000150023.1
stonin 1
chr2_+_69790968 0.89 ENSMUST00000180290.1
phosphatase, orphan 2
chr3_+_40540751 0.89 ENSMUST00000091186.3
inturned planar cell polarity effector homolog (Drosophila)
chr15_-_58847321 0.86 ENSMUST00000075109.5
ubiquitin-conjugating enzyme E2D 4
chr1_+_174050375 0.85 ENSMUST00000062665.3
olfactory receptor 432
chr14_+_41131777 0.83 ENSMUST00000022314.3
ENSMUST00000170719.1
surfactant associated protein A1
chr1_+_193173469 0.81 ENSMUST00000161235.1
ENSMUST00000110831.2
ENSMUST00000178744.1
RIKEN cDNA A130010J15 gene
chr1_+_182124737 0.81 ENSMUST00000111018.1
ENSMUST00000027792.5
signal recognition particle 9
chr8_+_106935720 0.80 ENSMUST00000047425.3
syntrophin, basic 2
chr12_+_10390756 0.76 ENSMUST00000020947.5
retinol dehydrogenase 14 (all-trans and 9-cis)
chr2_+_101624696 0.75 ENSMUST00000044031.3
recombination activating gene 2
chr11_-_100762928 0.74 ENSMUST00000107360.2
ENSMUST00000055083.3
hypocretin
chr3_-_59262825 0.73 ENSMUST00000050360.7
purinergic receptor P2Y, G-protein coupled 12
chr8_+_46492789 0.72 ENSMUST00000110371.1
acyl-CoA synthetase long-chain family member 1
chr17_+_13061099 0.72 ENSMUST00000086787.4
ENSMUST00000116666.1
t-complex protein 10b
chr2_-_91255995 0.72 ENSMUST00000180732.1
predicted gene, 17281
chr3_-_75270073 0.71 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr9_+_13765970 0.70 ENSMUST00000152532.1
myotubularin related protein 2
chr7_+_29238434 0.70 ENSMUST00000108237.1
Yip1 interacting factor homolog B (S. cerevisiae)
chr6_-_122856151 0.70 ENSMUST00000042081.8
complement component 3a receptor 1
chr17_+_36121666 0.69 ENSMUST00000173128.1
predicted gene, 19684
chr10_+_29143996 0.67 ENSMUST00000092629.2
SOGA family member 3
chr11_+_87582201 0.66 ENSMUST00000133202.1
septin 4
chr8_+_46986913 0.65 ENSMUST00000039840.7
ENSMUST00000119686.1
ectonucleotide pyrophosphatase/phosphodiesterase 6
chrX_+_139086226 0.64 ENSMUST00000033625.1
RIKEN cDNA 4930513O06 gene
chr6_+_6955993 0.64 ENSMUST00000040826.5
ACN9 homolog (S. cerevisiae)
chr9_+_62342449 0.64 ENSMUST00000156461.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chrX_-_136741155 0.64 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
mortality factor 4 like 2
chr19_+_24875679 0.63 ENSMUST00000073080.5
predicted gene 10053
chr3_-_94436574 0.62 ENSMUST00000029787.4
ornithine decarboxylase antizyme 3
chr5_+_145345254 0.59 ENSMUST00000079268.7
cytochrome P450, family 3, subfamily a, polypeptide 57
chr1_+_153874335 0.58 ENSMUST00000055314.3
predicted gene 5531
chr1_+_179961110 0.58 ENSMUST00000076687.5
ENSMUST00000097450.3
CDC42 binding protein kinase alpha
chr3_+_106486009 0.56 ENSMUST00000183271.1
ENSMUST00000061206.3
DENN/MADD domain containing 2D
chr7_+_102229999 0.56 ENSMUST00000120119.1
post-GPI attachment to proteins 2
chr6_-_24528013 0.54 ENSMUST00000023851.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chrX_+_103356464 0.54 ENSMUST00000116547.2
cysteine-rich hydrophobic domain 1
chr7_+_29238323 0.53 ENSMUST00000108238.1
ENSMUST00000032809.3
ENSMUST00000138128.1
Yip1 interacting factor homolog B (S. cerevisiae)
chr13_-_92030897 0.53 ENSMUST00000149630.1
RAS protein-specific guanine nucleotide-releasing factor 2
chr5_+_121802230 0.53 ENSMUST00000162995.1
ataxin 2
chr17_+_33824591 0.51 ENSMUST00000048249.6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7 (B14.5a)
chr1_-_136131171 0.51 ENSMUST00000146091.3
ENSMUST00000165464.1
ENSMUST00000166747.1
ENSMUST00000134998.1
predicted gene 15850
chr5_+_121749196 0.50 ENSMUST00000161064.1
ataxin 2
chr10_-_11082287 0.50 ENSMUST00000105561.2
ENSMUST00000044306.6
glutamate receptor, metabotropic 1
chr2_-_114201416 0.50 ENSMUST00000050668.3
zinc finger protein 770
chr18_+_37513652 0.49 ENSMUST00000061405.4
protocadherin beta 21
chr6_+_21949571 0.49 ENSMUST00000031680.3
ENSMUST00000115389.1
ENSMUST00000151473.1
inhibitor of growth family, member 3
chr6_-_129678908 0.47 ENSMUST00000118447.1
ENSMUST00000169545.1
ENSMUST00000032270.6
ENSMUST00000032271.6
killer cell lectin-like receptor subfamily C, member 1
chr11_-_78984946 0.47 ENSMUST00000108268.3
lectin, galactose binding, soluble 9
chr19_+_11965817 0.47 ENSMUST00000025590.9
oxysterol binding protein
chr2_-_79908428 0.44 ENSMUST00000102652.3
ENSMUST00000102651.3
phosphodiesterase 1A, calmodulin-dependent
chr11_-_78984831 0.44 ENSMUST00000073001.4
ENSMUST00000108269.3
lectin, galactose binding, soluble 9
chr14_+_52821860 0.43 ENSMUST00000181793.1
ENSMUST00000184436.1
T cell receptor alpha variable 6D-6
chr12_+_55239326 0.43 ENSMUST00000164243.1
signal recognition particle 54C
chr9_+_39993812 0.42 ENSMUST00000057161.3
olfactory receptor 978
chr5_+_121777929 0.41 ENSMUST00000160821.1
ataxin 2
chr8_+_85432686 0.41 ENSMUST00000180883.1
RIKEN cDNA 1700051O22 Gene
chr9_+_38719024 0.41 ENSMUST00000129598.1
von Willebrand factor A domain containing 5A
chr10_-_29362012 0.40 ENSMUST00000161508.1
ring finger protein 146
chr11_-_107348130 0.40 ENSMUST00000134763.1
phosphatidylinositol transfer protein, cytoplasmic 1
chr9_+_58582397 0.39 ENSMUST00000176557.1
ENSMUST00000114121.4
ENSMUST00000177064.1
neuroplastin
chr4_-_14796052 0.38 ENSMUST00000108276.1
ENSMUST00000023917.1
leucine rich repeat containing 69
chr13_+_18717289 0.38 ENSMUST00000072961.4
vacuolar protein sorting 41 (yeast)
chr13_+_65512678 0.38 ENSMUST00000081471.2
predicted gene 10139
chr3_+_93826020 0.37 ENSMUST00000081780.3
TD and POZ domain containing 3
chr12_+_55089202 0.37 ENSMUST00000021407.10
signal recognition particle 54A
chr1_-_59003443 0.37 ENSMUST00000054653.6
amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 11 (human)
chr11_-_102579071 0.37 ENSMUST00000107080.1
predicted gene 11627
chr12_+_52516077 0.37 ENSMUST00000110725.1
Rho GTPase activating protein 5
chrX_+_99042581 0.36 ENSMUST00000036606.7
START domain containing 8
chr1_+_165769392 0.35 ENSMUST00000040298.4
cellular repressor of E1A-stimulated genes 1
chr2_-_152464612 0.35 ENSMUST00000099206.2
defensin beta 23
chr11_-_110168073 0.35 ENSMUST00000044850.3
ATP-binding cassette, sub-family A (ABC1), member 9
chr16_-_10788649 0.35 ENSMUST00000051297.7
transition protein 2
chr18_+_37411674 0.33 ENSMUST00000051126.2
protocadherin beta 10
chr11_-_99422252 0.33 ENSMUST00000017741.3
keratin 12
chr14_-_51146757 0.33 ENSMUST00000080126.2
ribonuclease, RNase A family, 1 (pancreatic)
chr3_-_30509681 0.32 ENSMUST00000173495.1
MDS1 and EVI1 complex locus
chr4_+_43406435 0.31 ENSMUST00000098106.2
ENSMUST00000139198.1
RUN and SH3 domain containing 2
chr3_+_85915722 0.31 ENSMUST00000054148.7
predicted gene 9790
chrX_+_56609843 0.30 ENSMUST00000077741.5
ENSMUST00000114784.2
solute carrier family 9 (sodium/hydrogen exchanger), member 6
chr2_-_37647199 0.30 ENSMUST00000028279.3
spermatid perinuclear RNA binding protein
chr11_+_114091404 0.30 ENSMUST00000129365.1
RIKEN cDNA 1700025D23 gene
chr18_-_23038656 0.29 ENSMUST00000081423.6
nucleolar protein 4
chr5_+_64160207 0.28 ENSMUST00000101195.2
TBC1 domain family, member 1
chr3_-_57301919 0.28 ENSMUST00000029376.8
transmembrane 4 superfamily member 1
chr13_+_23695791 0.28 ENSMUST00000041052.2
histone cluster 1, H1t
chr3_+_66985680 0.27 ENSMUST00000065047.6
arginine/serine-rich coiled-coil 1
chr4_-_91376433 0.26 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_-_89752826 0.26 ENSMUST00000099765.1
olfactory receptor 1253
chr2_-_79908389 0.26 ENSMUST00000090756.4
phosphodiesterase 1A, calmodulin-dependent
chr3_-_30509752 0.25 ENSMUST00000172697.1
MDS1 and EVI1 complex locus
chr8_+_117701937 0.25 ENSMUST00000034304.7
hydroxysteroid (17-beta) dehydrogenase 2
chr1_+_179960472 0.25 ENSMUST00000097453.2
ENSMUST00000111117.1
CDC42 binding protein kinase alpha
chr17_-_25844417 0.25 ENSMUST00000176591.1
ras homolog gene family, member T2
chr2_-_172454742 0.25 ENSMUST00000161334.1
glucosaminyl (N-acetyl) transferase family member 7
chr11_+_71749914 0.24 ENSMUST00000150531.1
WSC domain containing 1
chr2_-_77946375 0.23 ENSMUST00000065889.3
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr3_+_67892189 0.23 ENSMUST00000063263.3
IQ motif containing J
chr2_-_77946331 0.22 ENSMUST00000111821.2
ENSMUST00000111818.1
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr1_+_164503306 0.21 ENSMUST00000181831.1
predicted gene, 26685
chr12_-_72917872 0.20 ENSMUST00000044000.5
RIKEN cDNA 4930447C04 gene
chr5_-_21701332 0.19 ENSMUST00000115217.1
ENSMUST00000060899.8
N-acyl phosphatidylethanolamine phospholipase D
chr1_-_156718894 0.18 ENSMUST00000086153.6
family with sequence similarity 20, member B
chr17_+_6079786 0.17 ENSMUST00000039487.3
general transcription factor IIH, polypeptide 5
chr5_+_24394388 0.17 ENSMUST00000115074.1
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr1_-_132229767 0.15 ENSMUST00000086544.4
predicted gene 10188
chr11_-_69795930 0.15 ENSMUST00000045971.8
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
chr19_+_39060998 0.15 ENSMUST00000087236.4
cytochrome P450, family 2, subfamily c, polypeptide 65
chr9_-_100506844 0.13 ENSMUST00000112874.3
non-catalytic region of tyrosine kinase adaptor protein 1
chr6_+_65590382 0.12 ENSMUST00000114236.1
TNFAIP3 interacting protein 3
chr13_-_18031616 0.11 ENSMUST00000099736.2
voltage-dependent anion channel 3, pseudogene 1
chr2_+_31759993 0.11 ENSMUST00000124089.1
c-abl oncogene 1, non-receptor tyrosine kinase
chr8_+_110618577 0.10 ENSMUST00000034190.9
Vac14 homolog (S. cerevisiae)
chr10_+_24076500 0.10 ENSMUST00000051133.5
trace amine-associated receptor 8A
chr3_+_102010138 0.10 ENSMUST00000066187.4
nescient helix loop helix 2
chr6_-_67491849 0.09 ENSMUST00000118364.1
interleukin 23 receptor
chr9_-_39957069 0.08 ENSMUST00000169307.2
olfactory receptor 976
chr2_-_34826187 0.08 ENSMUST00000113075.1
ENSMUST00000113080.2
ENSMUST00000091020.3
F-box and WD-40 domain protein 2
chr19_-_45591820 0.08 ENSMUST00000160003.1
ENSMUST00000162879.1
F-box and WD-40 domain protein 4
chr3_+_94643112 0.08 ENSMUST00000107276.1
predicted gene 10972
chr10_-_128180265 0.08 ENSMUST00000099139.1
RNA binding motif, single stranded interacting protein 2
chr15_+_37425554 0.08 ENSMUST00000022897.1
RIKEN cDNA 4930447A16 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.7 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.9 6.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.6 5.5 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.5 4.8 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.4 2.2 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.4 1.5 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.3 2.3 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.3 1.8 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.3 1.2 GO:1903383 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.3 1.3 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.3 2.6 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 0.7 GO:0002358 B cell homeostatic proliferation(GO:0002358)
0.2 1.0 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.2 3.3 GO:0015747 urate transport(GO:0015747)
0.2 1.4 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.2 1.3 GO:0033762 response to glucagon(GO:0033762)
0.2 1.0 GO:0009446 spermidine biosynthetic process(GO:0008295) putrescine biosynthetic process(GO:0009446)
0.2 0.9 GO:0043321 regulation of natural killer cell degranulation(GO:0043321) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.2 0.7 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 0.6 GO:1902047 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267) negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 3.6 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1 4.1 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.1 0.7 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.8 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.1 1.1 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 1.3 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 1.4 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.1 0.7 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.1 4.0 GO:0019236 response to pheromone(GO:0019236)
0.1 1.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 5.8 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.1 0.7 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.8 GO:0008228 opsonization(GO:0008228)
0.1 1.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 0.7 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.7 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.4 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.1 2.9 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 0.9 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.2 GO:0010705 meiotic DNA double-strand break processing involved in reciprocal meiotic recombination(GO:0010705)
0.1 2.0 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.1 0.3 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 1.1 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.7 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.2 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.0 2.0 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.0 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 1.1 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.6 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 2.2 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.0 0.8 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.3 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.3 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.3 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.8 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.5 GO:0044126 regulation of growth of symbiont in host(GO:0044126)
0.0 0.2 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.5 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.6 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.9 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 2.4 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 1.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.5 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 2.6 GO:0008360 regulation of cell shape(GO:0008360)
0.0 1.9 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.2 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.1 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.0 3.5 GO:0006869 lipid transport(GO:0006869)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0008091 spectrin(GO:0008091)
0.2 1.4 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.2 1.5 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.2 1.3 GO:0045293 mRNA editing complex(GO:0045293)
0.2 2.2 GO:0005579 membrane attack complex(GO:0005579)
0.2 6.1 GO:0030673 axolemma(GO:0030673)
0.1 1.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 1.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.3 GO:0045275 respiratory chain complex III(GO:0045275)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 2.4 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.7 GO:0097227 sperm annulus(GO:0097227)
0.1 0.5 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.1 0.4 GO:0033263 CORVET complex(GO:0033263)
0.1 0.3 GO:0044308 axonal spine(GO:0044308)
0.0 3.5 GO:0070469 respiratory chain(GO:0070469)
0.0 6.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.6 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.5 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 1.2 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 2.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.8 GO:0005771 multivesicular body(GO:0005771)
0.0 0.2 GO:0000801 central element(GO:0000801)
0.0 1.4 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 3.6 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 6.8 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 5.3 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.0 1.9 GO:0005770 late endosome(GO:0005770)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.1 GO:0031526 brush border membrane(GO:0031526)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 4.8 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
1.0 6.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.9 3.7 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.8 4.1 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.8 5.5 GO:0001851 complement component C3b binding(GO:0001851)
0.4 3.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.4 2.0 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.4 2.3 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.4 2.6 GO:0005534 galactose binding(GO:0005534)
0.3 2.9 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.3 1.4 GO:0004883 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.3 3.6 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.2 1.4 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.2 0.9 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.2 8.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 0.7 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.2 1.2 GO:0008312 7S RNA binding(GO:0008312)
0.2 1.3 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.2 0.6 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.2 4.0 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 1.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 1.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.1 0.9 GO:0016936 galactoside binding(GO:0016936)
0.1 0.5 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.1 3.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.4 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.7 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.7 GO:0004875 complement receptor activity(GO:0004875)
0.1 1.5 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.0 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 0.7 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 1.0 GO:0070403 NAD+ binding(GO:0070403)
0.1 2.2 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 2.0 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.3 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 1.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 2.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.7 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 2.2 GO:0005518 collagen binding(GO:0005518)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.9 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.5 GO:0023023 MHC protein complex binding(GO:0023023)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 1.6 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 1.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 5.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.1 2.9 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 2.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.1 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.8 PID IL3 PATHWAY IL3-mediated signaling events
0.0 1.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 1.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 3.0 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.6 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 7.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.3 2.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 2.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2 2.2 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 0.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.8 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 2.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 6.1 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.1 1.4 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 2.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.1 1.0 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 0.7 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.8 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 4.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 2.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.7 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 3.7 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.5 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.9 REACTOME MHC CLASS II ANTIGEN PRESENTATION Genes involved in MHC class II antigen presentation
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 1.1 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis