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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hmga2

Z-value: 1.31

Motif logo

Transcription factors associated with Hmga2

Gene Symbol Gene ID Gene Info
ENSMUSG00000056758.8 high mobility group AT-hook 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hmga2mm10_v2_chr10_-_120476469_1204765270.057.7e-01Click!

Activity profile of Hmga2 motif

Sorted Z-values of Hmga2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_41392356 14.20 ENSMUST00000049079.7
predicted gene 5771
chr6_+_41521782 12.77 ENSMUST00000070380.4
protease, serine, 2
chr6_+_41458923 11.11 ENSMUST00000031910.7
protease, serine, 1 (trypsin 1)
chr6_-_41035501 10.78 ENSMUST00000031931.5
RIKEN cDNA 2210010C04 gene
chr6_+_41302265 7.85 ENSMUST00000031913.4
trypsin 4
chr6_-_40999479 6.61 ENSMUST00000166306.1
predicted gene 2663
chr6_+_78380700 2.67 ENSMUST00000101272.1
regenerating islet-derived 3 alpha
chr7_+_13733502 2.40 ENSMUST00000086148.6
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
chr9_-_65422773 2.23 ENSMUST00000065894.5
solute carrier family 51, beta subunit
chr7_-_14123042 1.68 ENSMUST00000098809.2
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 3
chr17_-_43502773 1.66 ENSMUST00000024707.8
ENSMUST00000117137.1
meprin 1 alpha
chr19_+_39992424 1.66 ENSMUST00000049178.2
cytochrome P450, family 2. subfamily c, polypeptide 37
chr5_+_100845709 1.43 ENSMUST00000144623.1
1-acylglycerol-3-phosphate O-acyltransferase 9
chr7_-_13989588 1.30 ENSMUST00000165167.1
ENSMUST00000108520.2
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 4
chr2_+_68104671 1.16 ENSMUST00000042456.3
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr18_+_87756280 1.09 ENSMUST00000091776.5
predicted gene 5096
chr9_-_71168657 1.07 ENSMUST00000113570.1
aquaporin 9
chr15_-_82690499 1.07 ENSMUST00000100380.3
cytochrome P450, family 2, subfamily d, polypeptide 37, pseudogene
chr14_-_36919513 0.97 ENSMUST00000182042.1
coiled-coil serine rich 2
chr16_-_43979050 0.92 ENSMUST00000165648.1
ENSMUST00000036321.7
zinc finger, DHHC domain containing 23
chr11_+_62951191 0.88 ENSMUST00000035854.3
CMT1A duplicated region transcript 4
chrX_+_96456362 0.88 ENSMUST00000079322.5
ENSMUST00000113838.1
hephaestin
chr3_+_37348645 0.86 ENSMUST00000038885.3
fibroblast growth factor 2
chr16_+_30065333 0.85 ENSMUST00000023171.7
hairy and enhancer of split 1 (Drosophila)
chr16_-_36784924 0.78 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
solute carrier family 15 (H+/peptide transporter), member 2
chr12_+_57564111 0.78 ENSMUST00000101398.3
tetratricopeptide repeat domain 6
chr4_+_103114712 0.76 ENSMUST00000143417.1
mesoderm induction early response 1 homolog (Xenopus laevis
chr14_-_36919314 0.74 ENSMUST00000182797.1
coiled-coil serine rich 2
chr7_-_12422751 0.73 ENSMUST00000080348.5
zinc fingr protein 551
chr16_+_33185045 0.73 ENSMUST00000039733.8
oxysterol binding protein-like 11
chr10_-_93540016 0.71 ENSMUST00000016034.2
amidohydrolase domain containing 1
chr17_+_55749978 0.71 ENSMUST00000025004.6
EGF-like module containing, mucin-like, hormone receptor-like sequence 4
chr8_-_25091341 0.70 ENSMUST00000125466.1
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr10_-_81014902 0.68 ENSMUST00000126317.1
ENSMUST00000092285.3
ENSMUST00000117805.1
guanine nucleotide binding protein (G protein), gamma 7
chr5_-_87140318 0.68 ENSMUST00000067790.6
ENSMUST00000113327.1
UDP glucuronosyltransferase 2 family, polypeptide B5
chr9_+_58488568 0.64 ENSMUST00000085658.4
RIKEN cDNA 6030419C18 gene
chrX_-_140062712 0.63 ENSMUST00000133780.1
nucleoporin 62 C-terminal like
chr7_-_42642547 0.62 ENSMUST00000098503.2
RIKEN cDNA 9830147E19 gene
chr7_+_43440782 0.61 ENSMUST00000040227.1
claudin domain containing 2
chr3_+_98222148 0.61 ENSMUST00000029469.4
regenerating islet-derived family, member 4
chr5_+_21372642 0.60 ENSMUST00000035799.5
fibrinogen-like protein 2
chr2_-_122702615 0.59 ENSMUST00000005952.4
ENSMUST00000099457.3
solute carrier family 30 (zinc transporter), member 4
chr2_+_25080316 0.59 ENSMUST00000044078.3
ENSMUST00000114380.2
ectonucleoside triphosphate diphosphohydrolase 8
chr11_-_116307168 0.58 ENSMUST00000124281.1
exocyst complex component 7
chr9_-_97111117 0.55 ENSMUST00000085206.4
solute carrier family 25, member 36
chr15_-_63869297 0.54 ENSMUST00000089894.5
gasdermin C3
chr6_-_113719880 0.53 ENSMUST00000064993.5
ghrelin
chr16_+_96361749 0.53 ENSMUST00000000163.6
ENSMUST00000081093.3
ENSMUST00000113795.1
immunoglobulin superfamily, member 5
chr12_-_16800886 0.53 ENSMUST00000161998.1
gene regulated by estrogen in breast cancer protein
chr1_+_93235836 0.53 ENSMUST00000062202.7
sushi, nidogen and EGF-like domains 1
chr1_+_88055467 0.52 ENSMUST00000173325.1
UDP glycosyltransferase 1 family, polypeptide A10
chr2_-_98667264 0.51 ENSMUST00000099683.1
predicted gene 10800
chr19_+_40089688 0.51 ENSMUST00000068094.6
ENSMUST00000080171.2
cytochrome P450, family 2, subfamily c, polypeptide 50
chr2_-_75981967 0.51 ENSMUST00000099994.3
tetratricopeptide repeat domain 30A1
chrX_-_167264280 0.51 ENSMUST00000112170.1
ENSMUST00000133722.1
toll-like receptor 8
chr10_+_94550852 0.50 ENSMUST00000148910.1
ENSMUST00000117460.1
transmembrane and coiled coil domains 3
chr9_+_122923050 0.50 ENSMUST00000051667.7
ENSMUST00000148851.1
zinc finger protein 105
chr17_+_31208049 0.49 ENSMUST00000173776.1
ubiquitin associated and SH3 domain containing, A
chr8_-_84176552 0.49 ENSMUST00000070102.5
nanos homolog 3 (Drosophila)
chr19_+_6184363 0.48 ENSMUST00000025699.2
ENSMUST00000113528.1
RIKEN cDNA 1700123I01 gene
chr16_+_96361654 0.47 ENSMUST00000113794.1
immunoglobulin superfamily, member 5
chr15_-_63835949 0.47 ENSMUST00000089900.3
gasdermin C2
chr16_-_36784784 0.46 ENSMUST00000165531.1
solute carrier family 15 (H+/peptide transporter), member 2
chr1_+_46066738 0.44 ENSMUST00000069293.7
dynein, axonemal, heavy chain 7B
chr18_+_37447641 0.43 ENSMUST00000052387.3
protocadherin beta 14
chr7_-_101869012 0.42 ENSMUST00000123321.1
folate receptor 1 (adult)
chr9_-_8134294 0.42 ENSMUST00000037397.6
cDNA sequence AK129341
chr3_+_135485605 0.42 ENSMUST00000029814.9
mannosidase, beta A, lysosomal
chr2_-_148732457 0.42 ENSMUST00000028926.6
N-ethylmaleimide sensitive fusion protein attachment protein beta
chr4_+_57637816 0.40 ENSMUST00000150412.1
predicted gene 20459
chr8_+_61487715 0.39 ENSMUST00000034058.6
ENSMUST00000126575.1
carbonyl reductase 4
chr1_+_88055377 0.38 ENSMUST00000138182.1
ENSMUST00000113142.3
UDP glycosyltransferase 1 family, polypeptide A10
chr5_-_96164147 0.38 ENSMUST00000137207.1
CCR4-NOT transcription complex, subunit 6-like
chr13_+_49682191 0.38 ENSMUST00000172254.1
isoleucine-tRNA synthetase
chr4_-_120951664 0.37 ENSMUST00000106280.1
zinc finger protein 69
chr17_+_56628118 0.37 ENSMUST00000112979.2
catsper channel auxiliary subunit delta
chr10_+_69787431 0.36 ENSMUST00000183240.1
ankyrin 3, epithelial
chr2_-_110305730 0.36 ENSMUST00000046233.2
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr9_-_123260776 0.36 ENSMUST00000068140.4
transmembrane protein 158
chr5_+_87000838 0.36 ENSMUST00000031186.7
UDP glucuronosyltransferase 2 family, polypeptide B35
chr16_+_96235801 0.35 ENSMUST00000113800.2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 5
chr15_-_57265126 0.34 ENSMUST00000137764.1
ENSMUST00000022995.6
solute carrier family 22 (organic cation transporter), member 22
chr15_+_12205009 0.34 ENSMUST00000038172.8
myotubularin related protein 12
chr2_+_29124106 0.34 ENSMUST00000129544.1
senataxin
chr7_-_12422488 0.33 ENSMUST00000120220.1
zinc fingr protein 551
chr5_-_114858682 0.33 ENSMUST00000066959.4
predicted gene 9936
chr1_+_136676413 0.32 ENSMUST00000181491.1
predicted gene, 19705
chr7_+_49975228 0.32 ENSMUST00000107603.1
NEL-like 1
chr18_+_37411674 0.32 ENSMUST00000051126.2
protocadherin beta 10
chr17_+_73107982 0.32 ENSMUST00000130574.1
ENSMUST00000149064.1
ENSMUST00000067545.6
lysocardiolipin acyltransferase 1
chr11_+_83302817 0.32 ENSMUST00000142680.1
adaptor-related protein complex 2, beta 1 subunit
chr7_-_101868667 0.31 ENSMUST00000150184.1
folate receptor 1 (adult)
chr11_+_75999912 0.30 ENSMUST00000066408.5
RIKEN cDNA 1700016K19 gene
chr7_+_45526330 0.30 ENSMUST00000120985.1
ENSMUST00000051810.8
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4
chr15_+_12205068 0.30 ENSMUST00000071993.6
myotubularin related protein 12
chr14_+_25980039 0.30 ENSMUST00000173155.1
double homeobox B-like 1
chr9_+_13619990 0.29 ENSMUST00000159294.1
mastermind like 2 (Drosophila)
chr1_-_144004142 0.28 ENSMUST00000127206.1
regulator of G-protein signaling 2
chr11_-_116306652 0.28 ENSMUST00000126731.1
exocyst complex component 7
chr2_+_27676440 0.28 ENSMUST00000129514.1
retinoid X receptor alpha
chr10_+_25359798 0.27 ENSMUST00000053748.8
erythrocyte protein band 4.1-like 2
chr5_+_43515513 0.27 ENSMUST00000167522.1
ENSMUST00000144558.1
ENSMUST00000076939.6
C1q and tumor necrosis factor related protein 7
chr15_-_98145698 0.27 ENSMUST00000123626.1
ankyrin repeat and SOCS box-containing 8
chr2_-_80128834 0.27 ENSMUST00000102654.4
ENSMUST00000102655.3
phosphodiesterase 1A, calmodulin-dependent
chr6_-_128723046 0.26 ENSMUST00000112110.2
killer cell lectin-like receptor subfamily B member 1
chrX_-_147429189 0.25 ENSMUST00000033646.2
interleukin 13 receptor, alpha 2
chr14_+_53491115 0.25 ENSMUST00000181210.1
ENSMUST00000183488.1
T cell receptor alpha variable 6-5
chr10_-_130127055 0.24 ENSMUST00000074161.1
olfactory receptor 824
chr5_-_87424201 0.24 ENSMUST00000072818.5
UDP glucuronosyltransferase 2 family, polypeptide B38
chrX_+_7697131 0.24 ENSMUST00000049896.6
G patch domain and KOW motifs
chr1_+_132008285 0.23 ENSMUST00000146432.1
ELK4, member of ETS oncogene family
chr16_+_32277449 0.23 ENSMUST00000155649.1
ENSMUST00000014218.8
ENSMUST00000171474.1
ring finger protein 168
chr13_-_56548534 0.22 ENSMUST00000062806.4
leukocyte cell-derived chemotaxin 2
chr17_-_74459096 0.22 ENSMUST00000052124.7
NLR family, CARD domain containing 4
chr14_-_100149764 0.22 ENSMUST00000097079.4
Kruppel-like factor 12
chr5_+_90460889 0.21 ENSMUST00000031314.8
albumin
chr19_-_10525201 0.21 ENSMUST00000025570.6
succinate dehydrogenase complex assembly factor 2
chr5_-_17849783 0.21 ENSMUST00000170051.1
ENSMUST00000165232.1
CD36 antigen
chr3_-_64287417 0.21 ENSMUST00000170244.1
ENSMUST00000176328.1
vomeronasal 2, receptor 3
chrX_-_36991724 0.19 ENSMUST00000152291.1
septin 6
chr15_-_98145625 0.19 ENSMUST00000059112.5
ankyrin repeat and SOCS box-containing 8
chr4_+_44756609 0.18 ENSMUST00000143385.1
zinc finger, CCHC domain containing 7
chr10_+_58446845 0.17 ENSMUST00000003310.5
RAN binding protein 2
chr17_+_46772635 0.17 ENSMUST00000071430.5
RIKEN cDNA 2310039H08 gene
chrM_+_9870 0.15 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr1_-_24612700 0.15 ENSMUST00000088336.1
predicted gene 10222
chr16_+_29579347 0.14 ENSMUST00000038867.6
ENSMUST00000161186.1
optic atrophy 1
chr7_-_10495322 0.14 ENSMUST00000032551.7
zinc finger protein interacting with K protein 1
chr2_-_102186322 0.13 ENSMUST00000111222.1
ENSMUST00000058790.5
low density lipoprotein receptor class A domain containing 3
chr17_-_6961156 0.13 ENSMUST00000063683.6
T cell activation GTPase activating protein 1
chr16_-_26371828 0.12 ENSMUST00000023154.2
claudin 1
chr17_-_50094277 0.12 ENSMUST00000113195.1
raftlin lipid raft linker 1
chr15_-_103755439 0.12 ENSMUST00000078842.7
mucin-like 1
chr7_-_97738222 0.11 ENSMUST00000084986.6
aquaporin 11
chr11_+_83942062 0.11 ENSMUST00000049257.7
DEAD (Asp-Glu-Ala-Asp) box polypeptide 52
chr11_+_77462325 0.10 ENSMUST00000102493.1
coronin 6
chr2_+_78051155 0.10 ENSMUST00000145972.1
RIKEN cDNA 4930440I19 gene
chr7_+_129591859 0.09 ENSMUST00000084519.5
WD repeat domain 11
chr7_-_133015248 0.08 ENSMUST00000169570.1
C-terminal binding protein 2
chr17_+_8165501 0.08 ENSMUST00000097419.3
ENSMUST00000024636.8
Fgfr1 oncogene partner
chr4_-_25281801 0.08 ENSMUST00000102994.3
UFM1 specific ligase 1
chr6_+_35252724 0.06 ENSMUST00000136110.1
RIKEN cDNA 1810058I24 gene
chr9_-_71485893 0.06 ENSMUST00000034720.5
polymerase (RNA) II (DNA directed) polypeptide M
chr16_+_29579331 0.06 ENSMUST00000160597.1
optic atrophy 1
chr13_-_66852017 0.06 ENSMUST00000059329.6
predicted gene, 17449
chr4_+_126286792 0.06 ENSMUST00000070132.6
collagen, type VIII, alpha 2
chr5_-_32133045 0.06 ENSMUST00000031308.6
predicted gene 10463
chr6_+_125039760 0.05 ENSMUST00000140131.1
ENSMUST00000032480.7
inhibitor of growth family, member 4
chr6_+_21949571 0.05 ENSMUST00000031680.3
ENSMUST00000115389.1
ENSMUST00000151473.1
inhibitor of growth family, member 3
chr4_+_44756553 0.05 ENSMUST00000107824.2
zinc finger, CCHC domain containing 7
chr7_-_24724237 0.05 ENSMUST00000081657.4
predicted gene 4763
chr4_-_58912678 0.04 ENSMUST00000144512.1
ENSMUST00000102889.3
ENSMUST00000055822.8
expressed sequence AI314180
chrX_+_101640056 0.04 ENSMUST00000119299.1
ENSMUST00000044475.4
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr6_-_136401830 0.04 ENSMUST00000058713.7
RIKEN cDNA E330021D16 gene
chr6_-_142473075 0.04 ENSMUST00000032371.7
glycogen synthase 2
chr3_+_92365178 0.04 ENSMUST00000050397.1
small proline-rich protein 2F
chr8_+_119344490 0.03 ENSMUST00000034300.6
heat shock factor binding protein 1
chr8_-_3878549 0.03 ENSMUST00000011445.6
CD209d antigen
chr16_+_87454976 0.02 ENSMUST00000119504.1
ENSMUST00000131356.1
ubiquitin specific peptidase 16
chr11_-_65159890 0.02 ENSMUST00000020855.3
ENSMUST00000108696.1
RIKEN cDNA 1700086D15 gene
chr16_-_19286837 0.02 ENSMUST00000056727.4
olfactory receptor 164
chr5_-_31220491 0.02 ENSMUST00000031032.7
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr11_-_84069179 0.01 ENSMUST00000138208.1
dual specificity phosphatase 14
chr9_+_70012540 0.01 ENSMUST00000118198.1
ENSMUST00000119905.1
ENSMUST00000119413.1
ENSMUST00000140305.1
ENSMUST00000122087.1
general transcription factor II A, 2
chr14_-_62456286 0.00 ENSMUST00000165651.1
ENSMUST00000022501.3
guanylate cyclase 1, soluble, beta 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Hmga2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 12.3 GO:0031000 response to caffeine(GO:0031000)
0.3 0.9 GO:0021558 trochlear nerve development(GO:0021558) auditory receptor cell fate determination(GO:0042668) negative regulation of forebrain neuron differentiation(GO:2000978)
0.3 1.1 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.2 2.2 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.2 1.2 GO:0042938 dipeptide transport(GO:0042938)
0.2 2.7 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.2 33.7 GO:0007586 digestion(GO:0007586)
0.2 0.9 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.1 0.7 GO:0006548 histidine catabolic process(GO:0006548)
0.1 1.2 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.5 GO:2001183 positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.3 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.1 0.6 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.3 GO:0016598 protein arginylation(GO:0016598)
0.1 0.5 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.7 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.1 0.4 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.1 0.3 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.1 0.7 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 0.9 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.2 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 2.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.8 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.1 0.4 GO:0044597 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.1 0.3 GO:0006447 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.1 0.8 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 0.2 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.6 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
0.0 0.3 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.0 0.6 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.0 0.4 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.5 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.4 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.2 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636) positive regulation of neuron maturation(GO:0014042)
0.0 0.4 GO:1900827 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.3 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.1 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.3 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.0 0.3 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.9 GO:0006825 copper ion transport(GO:0006825)
0.0 0.5 GO:1900151 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.5 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.4 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 1.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 0.2 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.1 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.6 GO:1901998 toxin transport(GO:1901998)
0.0 0.4 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.7 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 0.8 GO:0032584 growth cone membrane(GO:0032584)
0.1 0.6 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 0.2 GO:0005940 septin ring(GO:0005940)
0.0 0.4 GO:0036128 CatSper complex(GO:0036128)
0.0 0.4 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.7 GO:0031362 intrinsic component of external side of plasma membrane(GO:0031233) anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 61.5 GO:0005615 extracellular space(GO:0005615)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.5 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.4 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.0 GO:0004027 alcohol sulfotransferase activity(GO:0004027)
0.4 1.2 GO:0042936 dipeptide transporter activity(GO:0042936)
0.3 63.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.3 1.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.3 0.9 GO:0071820 N-box binding(GO:0071820)
0.2 1.1 GO:0005345 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.2 0.5 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.1 0.5 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.1 0.3 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.4 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 0.7 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.9 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.2 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 0.7 GO:0051870 methotrexate binding(GO:0051870)
0.1 1.7 GO:0070330 aromatase activity(GO:0070330)
0.0 2.4 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.3 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.9 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.4 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.6 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.2 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.4 GO:0048038 quinone binding(GO:0048038) NADPH binding(GO:0070402)
0.0 0.6 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.7 GO:0043236 laminin binding(GO:0043236)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.6 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.7 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.0 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0015250 water channel activity(GO:0015250)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 24.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.9 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 3.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.1 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 0.8 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 12.8 REACTOME DEFENSINS Genes involved in Defensins
0.4 11.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.9 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 1.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.7 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 1.2 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 0.9 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes