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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Hdx

Z-value: 3.68

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Transcription factors associated with Hdx

Gene Symbol Gene ID Gene Info
Hdx
ENSMUSG00000034551.6 highly divergent homeobox

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hdxmm10_v2_chrX_-_111697069_111697127-0.564.0e-04Click!

Activity profile of Hdx motif

Sorted Z-values of Hdx motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_62150810 43.62 ENSMUST00000077719.3
Mup21
major urinary protein 21
chr4_-_60662358 42.26 ENSMUST00000084544.4
ENSMUST00000098046.3
Mup11
major urinary protein 11
chr4_-_60139857 39.80 ENSMUST00000107490.4
ENSMUST00000074700.2
Mup2
major urinary protein 2
chr4_-_60582152 38.30 ENSMUST00000098047.2
Mup10
major urinary protein 10
chr4_-_61303998 37.20 ENSMUST00000071005.8
ENSMUST00000075206.5
Mup14
major urinary protein 14
chr4_-_60421933 36.68 ENSMUST00000107506.2
ENSMUST00000122381.1
ENSMUST00000118759.1
ENSMUST00000122177.1
Mup9
major urinary protein 9
chr4_-_61674094 36.67 ENSMUST00000098040.3
Mup18
major urinary protein 18
chr4_-_60222580 36.12 ENSMUST00000095058.4
ENSMUST00000163931.1
Mup8
major urinary protein 8
chr4_-_61303802 35.65 ENSMUST00000125461.1
Mup14
major urinary protein 14
chr15_+_4727175 16.12 ENSMUST00000162585.1
C6
complement component 6
chr15_+_4727202 15.55 ENSMUST00000161997.1
ENSMUST00000022788.8
C6
complement component 6
chr5_-_87092546 15.35 ENSMUST00000132667.1
ENSMUST00000145617.1
ENSMUST00000094649.4
Ugt2b36
UDP glucuronosyltransferase 2 family, polypeptide B36
chr15_+_4727265 13.40 ENSMUST00000162350.1
C6
complement component 6
chr1_+_182564994 12.99 ENSMUST00000048941.7
ENSMUST00000168514.1
Capn8
calpain 8
chr14_+_37068042 11.17 ENSMUST00000057176.3
Lrit2
leucine-rich repeat, immunoglobulin-like and transmembrane domains 2
chr1_-_139781236 9.32 ENSMUST00000027612.8
ENSMUST00000111989.2
ENSMUST00000111986.2
Gm4788
predicted gene 4788
chr19_-_46672883 9.16 ENSMUST00000026012.7
Cyp17a1
cytochrome P450, family 17, subfamily a, polypeptide 1
chr6_-_3968357 8.08 ENSMUST00000031674.8
Tfpi2
tissue factor pathway inhibitor 2
chr15_+_10177623 7.90 ENSMUST00000124470.1
Prlr
prolactin receptor
chr17_-_34743849 7.62 ENSMUST00000069507.8
C4b
complement component 4B (Chido blood group)
chr12_-_98577940 7.49 ENSMUST00000110113.1
Kcnk10
potassium channel, subfamily K, member 10
chr10_+_62071014 7.38 ENSMUST00000053865.5
Gm5424
predicted gene 5424
chr17_+_3397189 7.14 ENSMUST00000072156.6
Tiam2
T cell lymphoma invasion and metastasis 2
chr5_-_86518578 6.46 ENSMUST00000134179.1
Tmprss11g
transmembrane protease, serine 11g
chr5_-_87535113 6.37 ENSMUST00000120150.1
Sult1b1
sulfotransferase family 1B, member 1
chr2_+_69380431 6.03 ENSMUST00000063690.3
Dhrs9
dehydrogenase/reductase (SDR family) member 9
chr1_+_88070765 5.87 ENSMUST00000073772.4
Ugt1a9
UDP glucuronosyltransferase 1 family, polypeptide A9
chr15_+_10249560 5.68 ENSMUST00000134410.1
Prlr
prolactin receptor
chr1_+_13668739 5.38 ENSMUST00000088542.3
Xkr9
X Kell blood group precursor related family member 9 homolog
chr13_-_56548534 5.17 ENSMUST00000062806.4
Lect2
leukocyte cell-derived chemotaxin 2
chr7_+_13398115 5.01 ENSMUST00000005791.7
Cabp5
calcium binding protein 5
chr1_-_140183404 5.00 ENSMUST00000066859.6
ENSMUST00000111976.2
Cfh
complement component factor h
chr2_+_120977017 4.99 ENSMUST00000067582.7
Tmem62
transmembrane protein 62
chr1_-_184811170 4.75 ENSMUST00000048462.6
ENSMUST00000110992.2
Marc1
mitochondrial amidoxime reducing component 1
chr17_+_31433054 4.75 ENSMUST00000136384.1
Pde9a
phosphodiesterase 9A
chr16_+_23107413 4.56 ENSMUST00000023599.6
ENSMUST00000168891.1
Eif4a2
eukaryotic translation initiation factor 4A2
chr3_+_62419668 4.50 ENSMUST00000161057.1
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr15_-_99087817 4.40 ENSMUST00000064462.3
C1ql4
complement component 1, q subcomponent-like 4
chr9_-_45204083 4.34 ENSMUST00000034599.8
Tmprss4
transmembrane protease, serine 4
chr9_+_70207342 4.12 ENSMUST00000034745.7
Myo1e
myosin IE
chr17_-_35895920 3.94 ENSMUST00000059740.8
2310061I04Rik
RIKEN cDNA 2310061I04 gene
chrX_-_21089229 3.75 ENSMUST00000040667.6
Zfp300
zinc finger protein 300
chr1_-_140183283 3.67 ENSMUST00000111977.1
Cfh
complement component factor h
chr14_-_45477856 3.62 ENSMUST00000141424.1
Fermt2
fermitin family homolog 2 (Drosophila)
chr8_-_84773381 3.58 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr4_+_97777606 3.57 ENSMUST00000075448.6
ENSMUST00000092532.6
Nfia
nuclear factor I/A
chr11_+_97801917 3.42 ENSMUST00000127033.2
Lasp1
LIM and SH3 protein 1
chr10_+_34483400 3.35 ENSMUST00000019913.7
ENSMUST00000170771.1
Frk
fyn-related kinase
chr2_+_116900152 3.32 ENSMUST00000126467.1
ENSMUST00000128305.1
ENSMUST00000155323.1
D330050G23Rik
RIKEN cDNA D330050G23 gene
chr9_-_71168657 3.31 ENSMUST00000113570.1
Aqp9
aquaporin 9
chr14_+_52810934 3.30 ENSMUST00000103646.3
Trav10d
T cell receptor alpha variable 10D
chr6_+_54267131 3.23 ENSMUST00000114402.2
Chn2
chimerin (chimaerin) 2
chr4_+_89137122 3.15 ENSMUST00000058030.7
Mtap
methylthioadenosine phosphorylase
chr17_-_45686899 3.14 ENSMUST00000156254.1
Tmem63b
transmembrane protein 63b
chr2_-_126783416 3.09 ENSMUST00000130356.1
ENSMUST00000028842.2
Usp50
ubiquitin specific peptidase 50
chr8_-_109579056 3.08 ENSMUST00000074898.6
Hp
haptoglobin
chr6_-_4086914 3.05 ENSMUST00000049166.4
Bet1
blocked early in transport 1 homolog (S. cerevisiae)
chr10_-_77799133 3.04 ENSMUST00000178581.1
Gm19668
predicted gene, 19668
chr2_-_90022064 3.04 ENSMUST00000099758.1
Olfr1264
olfactory receptor 1264
chr9_+_3023547 3.03 ENSMUST00000099046.3
Gm10718
predicted gene 10718
chr4_+_145696161 3.03 ENSMUST00000180014.1
Gm13242
predicted gene 13242
chr10_-_127121125 3.01 ENSMUST00000164259.1
ENSMUST00000080975.4
Os9
amplified in osteosarcoma
chr9_+_3025417 2.96 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr11_+_98446826 2.57 ENSMUST00000019456.4
Grb7
growth factor receptor bound protein 7
chr11_-_69369377 2.56 ENSMUST00000092971.6
ENSMUST00000108661.1
Chd3
chromodomain helicase DNA binding protein 3
chr14_-_19418930 2.53 ENSMUST00000177817.1
Gm21738
predicted gene, 21738
chr6_-_130193112 2.45 ENSMUST00000112032.1
ENSMUST00000071554.2
Klra9
killer cell lectin-like receptor subfamily A, member 9
chr18_-_35498856 2.41 ENSMUST00000025215.8
Sil1
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr9_+_3013140 2.34 ENSMUST00000143083.2
Gm10721
predicted gene 10721
chr10_+_127420334 2.30 ENSMUST00000171434.1
R3hdm2
R3H domain containing 2
chr11_-_69685537 2.27 ENSMUST00000018896.7
Tnfsf13
tumor necrosis factor (ligand) superfamily, member 13
chr6_+_34709610 2.22 ENSMUST00000031775.6
Cald1
caldesmon 1
chr3_-_146770603 2.22 ENSMUST00000106138.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr13_+_24327415 2.17 ENSMUST00000167746.1
Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr11_+_115765420 2.15 ENSMUST00000093912.4
ENSMUST00000136720.1
ENSMUST00000103034.3
ENSMUST00000141871.1
2310067B10Rik
RIKEN cDNA 2310067B10 gene
chr2_-_121807024 2.13 ENSMUST00000138157.1
Frmd5
FERM domain containing 5
chr7_-_7337493 2.12 ENSMUST00000072475.6
ENSMUST00000174368.1
Vmn2r30
vomeronasal 2, receptor 30
chr2_-_121806988 2.10 ENSMUST00000110592.1
Frmd5
FERM domain containing 5
chr9_+_3004457 2.08 ENSMUST00000178348.1
Gm11168
predicted gene 11168
chr11_+_117232254 2.08 ENSMUST00000106354.2
Sept9
septin 9
chr3_+_116008220 2.08 ENSMUST00000106502.1
Extl2
exostoses (multiple)-like 2
chr5_-_146963742 2.02 ENSMUST00000125217.1
ENSMUST00000110564.1
ENSMUST00000066675.3
ENSMUST00000016654.2
ENSMUST00000110566.1
ENSMUST00000140526.1
Mtif3
mitochondrial translational initiation factor 3
chrX_+_134187492 2.02 ENSMUST00000064476.4
Arl13a
ADP-ribosylation factor-like 13A
chr7_-_89980935 2.01 ENSMUST00000107234.1
Eed
embryonic ectoderm development
chr2_-_155729359 1.99 ENSMUST00000040833.4
Edem2
ER degradation enhancer, mannosidase alpha-like 2
chr19_-_32061438 1.94 ENSMUST00000096119.4
Asah2
N-acylsphingosine amidohydrolase 2
chr1_+_180101144 1.91 ENSMUST00000133890.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr13_+_60601921 1.90 ENSMUST00000077453.5
Dapk1
death associated protein kinase 1
chr2_-_37359274 1.90 ENSMUST00000009174.8
Pdcl
phosducin-like
chr17_+_33432890 1.87 ENSMUST00000174088.2
Actl9
actin-like 9
chr3_-_34081256 1.81 ENSMUST00000117223.1
ENSMUST00000120805.1
ENSMUST00000011029.5
ENSMUST00000108195.3
Dnajc19
DnaJ (Hsp40) homolog, subfamily C, member 19
chr7_-_7247328 1.78 ENSMUST00000170922.1
Vmn2r29
vomeronasal 2, receptor 29
chr9_+_3037111 1.72 ENSMUST00000177969.1
Gm10715
predicted gene 10715
chr13_+_41249841 1.70 ENSMUST00000165561.2
Smim13
small integral membrane protein 13
chr5_+_107597696 1.67 ENSMUST00000112651.1
ENSMUST00000112654.1
ENSMUST00000065422.5
Rpap2
RNA polymerase II associated protein 2
chr3_+_121671317 1.66 ENSMUST00000098646.3
4930432M17Rik
RIKEN cDNA 4930432M17 gene
chr3_-_146770218 1.65 ENSMUST00000106137.1
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr7_+_81057589 1.64 ENSMUST00000107348.1
Alpk3
alpha-kinase 3
chr11_+_102285161 1.59 ENSMUST00000156326.1
Tmub2
transmembrane and ubiquitin-like domain containing 2
chr3_-_154330543 1.54 ENSMUST00000184966.1
ENSMUST00000177846.2
Lhx8
LIM homeobox protein 8
chr2_+_97467657 1.52 ENSMUST00000059049.7
Lrrc4c
leucine rich repeat containing 4C
chr14_-_68655804 1.52 ENSMUST00000111072.1
ENSMUST00000022642.5
Adam28
a disintegrin and metallopeptidase domain 28
chr4_-_43031429 1.49 ENSMUST00000136326.1
Stoml2
stomatin (Epb7.2)-like 2
chr5_+_107597760 1.48 ENSMUST00000112655.1
Rpap2
RNA polymerase II associated protein 2
chr19_+_12460749 1.47 ENSMUST00000081035.7
Mpeg1
macrophage expressed gene 1
chr9_+_3034599 1.42 ENSMUST00000178641.1
Gm17535
predicted gene, 17535
chr9_-_83254460 1.37 ENSMUST00000184080.1
ENSMUST00000184100.1
RP23-341H6.1
RP23-341H6.1
chr7_+_131174400 1.37 ENSMUST00000050586.5
5430419D17Rik
RIKEN cDNA 5430419D17 gene
chr11_-_100050542 1.36 ENSMUST00000007318.1
Krt31
keratin 31
chr14_+_62663665 1.35 ENSMUST00000171692.1
Serpine3
serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 3
chrX_+_143518671 1.31 ENSMUST00000134402.1
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr18_-_31949571 1.31 ENSMUST00000064016.5
Gpr17
G protein-coupled receptor 17
chr12_-_81568474 1.29 ENSMUST00000008582.3
Adam21
a disintegrin and metallopeptidase domain 21
chr4_-_134000857 1.28 ENSMUST00000105887.1
ENSMUST00000012262.5
ENSMUST00000144668.1
ENSMUST00000105889.3
Dhdds
dehydrodolichyl diphosphate synthase
chr4_+_3938904 1.19 ENSMUST00000120732.1
ENSMUST00000041122.4
ENSMUST00000121651.1
ENSMUST00000121210.1
ENSMUST00000119307.1
ENSMUST00000123769.1
Chchd7
coiled-coil-helix-coiled-coil-helix domain containing 7
chr4_-_43031370 1.18 ENSMUST00000138030.1
Stoml2
stomatin (Epb7.2)-like 2
chr4_+_124880899 1.18 ENSMUST00000059343.6
Epha10
Eph receptor A10
chr7_-_9841325 1.18 ENSMUST00000170131.1
Vmn2r47
vomeronasal 2, receptor 47
chr16_-_37539781 1.14 ENSMUST00000023525.8
Gtf2e1
general transcription factor II E, polypeptide 1 (alpha subunit)
chr11_-_48946148 1.12 ENSMUST00000104958.1
Psme2b
protease (prosome, macropain) activator subunit 2B
chr5_+_32863700 1.12 ENSMUST00000149350.1
ENSMUST00000118698.1
ENSMUST00000150130.1
ENSMUST00000087897.4
ENSMUST00000119705.1
ENSMUST00000125574.1
ENSMUST00000049780.6
Depdc5
DEP domain containing 5
chr1_+_87327008 1.09 ENSMUST00000172794.1
ENSMUST00000164992.2
Gigyf2
GRB10 interacting GYF protein 2
chr7_-_9572288 1.09 ENSMUST00000174433.1
Gm10302
predicted gene 10302
chr1_+_130865669 1.09 ENSMUST00000038829.5
Faim3
Fas apoptotic inhibitory molecule 3
chr5_-_109097864 1.04 ENSMUST00000095922.3
Vmn2r12
vomeronasal 2, receptor 12
chr11_-_35798884 1.01 ENSMUST00000160726.2
Fbll1
fibrillarin-like 1
chr13_+_60602182 1.01 ENSMUST00000044083.7
Dapk1
death associated protein kinase 1
chr12_-_27160311 1.00 ENSMUST00000182473.1
ENSMUST00000177636.1
ENSMUST00000183238.1
Gm9866
predicted gene 9866
chr7_-_128596278 0.99 ENSMUST00000179317.1
Gm7258
predicted gene 7258
chr8_-_41016295 0.98 ENSMUST00000131965.1
Mtus1
mitochondrial tumor suppressor 1
chr10_+_85928491 0.98 ENSMUST00000170396.1
Ascl4
achaete-scute complex homolog 4 (Drosophila)
chr5_+_107437908 0.97 ENSMUST00000094541.2
Btbd8
BTB (POZ) domain containing 8
chr9_+_3005125 0.97 ENSMUST00000179881.1
Gm11168
predicted gene 11168
chr3_-_129755305 0.96 ENSMUST00000029653.2
Egf
epidermal growth factor
chr6_-_143947061 0.94 ENSMUST00000124233.1
Sox5
SRY-box containing gene 5
chrX_+_143518576 0.94 ENSMUST00000033640.7
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr12_-_27160498 0.92 ENSMUST00000182592.1
Gm9866
predicted gene 9866
chr14_-_36968679 0.91 ENSMUST00000067700.6
Ccser2
coiled-coil serine rich 2
chr14_-_72602945 0.91 ENSMUST00000162825.1
Fndc3a
fibronectin type III domain containing 3A
chr16_+_35938470 0.87 ENSMUST00000114878.1
Parp9
poly (ADP-ribose) polymerase family, member 9
chr11_+_4257557 0.86 ENSMUST00000066283.5
Lif
leukemia inhibitory factor
chr9_+_3036877 0.86 ENSMUST00000155807.2
Gm10715
predicted gene 10715
chr16_-_50330987 0.85 ENSMUST00000114488.1
Bbx
bobby sox homolog (Drosophila)
chr14_+_53845234 0.83 ENSMUST00000103674.4
Trav19
T cell receptor alpha variable 19
chr4_+_43406435 0.83 ENSMUST00000098106.2
ENSMUST00000139198.1
Rusc2
RUN and SH3 domain containing 2
chr10_-_130429612 0.83 ENSMUST00000171811.2
Vmn2r85
vomeronasal 2, receptor 85
chr9_+_94669876 0.82 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr6_-_57535422 0.81 ENSMUST00000042766.3
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr1_+_180109192 0.81 ENSMUST00000143176.1
ENSMUST00000135056.1
Cdc42bpa
CDC42 binding protein kinase alpha
chr6_-_143947092 0.81 ENSMUST00000144289.1
ENSMUST00000111748.1
Sox5
SRY-box containing gene 5
chr9_+_3000922 0.80 ENSMUST00000151376.2
Gm10722
predicted gene 10722
chr11_-_98193260 0.79 ENSMUST00000092735.5
ENSMUST00000107545.2
Med1
mediator complex subunit 1
chr7_-_42933789 0.79 ENSMUST00000163803.1
Vmn2r63
vomeronasal 2, receptor 63
chr9_+_3015654 0.77 ENSMUST00000099050.3
Gm10720
predicted gene 10720
chr5_-_26004798 0.77 ENSMUST00000168875.1
Gm1979
predicted gene 1979
chr8_+_109493982 0.74 ENSMUST00000034162.6
Pmfbp1
polyamine modulated factor 1 binding protein 1
chr5_-_26089291 0.73 ENSMUST00000094946.4
Gm10471
predicted gene 10471
chr4_-_97584605 0.69 ENSMUST00000107067.1
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr13_-_67729109 0.68 ENSMUST00000073157.6
Zfp71-rs1
zinc finger protein 71, related sequence
chr5_-_25926215 0.68 ENSMUST00000167847.2
Gm21655
predicted gene, 21655
chr13_+_43370710 0.66 ENSMUST00000066804.4
Sirt5
sirtuin 5
chr13_-_66355385 0.66 ENSMUST00000099416.3
Vmn2r-ps104
vomeronasal 2, receptor, pseudogene 104
chr14_+_13454010 0.66 ENSMUST00000112656.2
Synpr
synaptoporin
chr5_-_107597577 0.66 ENSMUST00000100949.3
ENSMUST00000078021.6
Glmn
glomulin, FKBP associated protein
chr5_+_26257691 0.64 ENSMUST00000074148.6
Gm7361
predicted gene 7361
chr18_+_77375065 0.64 ENSMUST00000123410.1
Loxhd1
lipoxygenase homology domains 1
chr16_+_14705832 0.64 ENSMUST00000023356.6
Snai2
snail homolog 2 (Drosophila)
chr7_+_13398150 0.61 ENSMUST00000117400.1
Cabp5
calcium binding protein 5
chr5_-_25954344 0.61 ENSMUST00000162387.4
Gm21671
predicted gene, 21671
chr16_-_50432340 0.61 ENSMUST00000066037.6
ENSMUST00000089399.4
ENSMUST00000089404.3
ENSMUST00000114477.1
ENSMUST00000138166.1
Bbx
bobby sox homolog (Drosophila)
chr8_-_85025268 0.59 ENSMUST00000064314.8
Asna1
arsA arsenite transporter, ATP-binding, homolog 1 (bacterial)
chr16_+_22951072 0.58 ENSMUST00000023590.8
Hrg
histidine-rich glycoprotein
chr9_+_45055166 0.57 ENSMUST00000114664.1
ENSMUST00000093856.3
Mpzl3
myelin protein zero-like 3
chr1_+_87327044 0.57 ENSMUST00000173173.1
Gigyf2
GRB10 interacting GYF protein 2
chr9_+_87729285 0.55 ENSMUST00000181359.1
D030062O11Rik
RIKEN cDNA D030062O11 gene
chr5_-_26105362 0.54 ENSMUST00000063524.2
5031410I06Rik
RIKEN cDNA 5031410I06 gene
chr5_-_15714236 0.54 ENSMUST00000095005.5
ENSMUST00000179506.1
Speer4c
spermatogenesis associated glutamate (E)-rich protein 4c
chr5_-_109192107 0.52 ENSMUST00000053253.8
Vmn2r13
vomeronasal 2, receptor 13
chr5_-_26121421 0.52 ENSMUST00000088236.3
Gm10220
predicted gene 10220
chr5_-_14938429 0.51 ENSMUST00000159973.2
Speer4e
spermatogenesis associated glutamate (E)-rich protein 4e
chr5_-_26039506 0.50 ENSMUST00000079447.2
Speer4a
spermatogenesis associated glutamate (E)-rich protein 4a
chr6_-_130699016 0.50 ENSMUST00000182643.1
Gm26919
predicted gene, 26919
chr2_-_41789078 0.47 ENSMUST00000167270.2
Lrp1b
low density lipoprotein-related protein 1B (deleted in tumors)
chr15_+_102954427 0.46 ENSMUST00000001701.3
Hoxc11
homeobox C11
chr10_-_130497379 0.45 ENSMUST00000164227.2
Vmn2r87
vomeronasal 2, receptor 87
chr5_-_14978935 0.43 ENSMUST00000096953.4
Gm10354
predicted gene 10354
chr3_-_145099024 0.43 ENSMUST00000040465.6
Clca5
chloride channel calcium activated 5
chr5_+_15619064 0.42 ENSMUST00000095006.2
Speer4d
spermatogenesis associated glutamate (E)-rich protein 4d
chr18_-_39489157 0.42 ENSMUST00000131885.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr1_+_87326997 0.40 ENSMUST00000027475.8
Gigyf2
GRB10 interacting GYF protein 2
chr7_-_41872670 0.40 ENSMUST00000171671.1
Vmn2r58
vomeronasal 2, receptor 58
chr4_-_97584612 0.39 ENSMUST00000107068.2
E130114P18Rik
RIKEN cDNA E130114P18 gene
chr7_-_8260599 0.39 ENSMUST00000066317.4
Vmn2r43
vomeronasal 2, receptor 43
chr9_+_45055211 0.39 ENSMUST00000114663.2
Mpzl3
myelin protein zero-like 3
chr16_-_4624984 0.38 ENSMUST00000014445.6
Pam16
presequence translocase-asssociated motor 16 homolog (S. cerevisiae)
chr11_+_95666957 0.36 ENSMUST00000125172.1
ENSMUST00000036374.5
Phb
prohibitin
chr7_-_44257204 0.35 ENSMUST00000012921.7
Acpt
acid phosphatase, testicular
chr5_-_129879038 0.35 ENSMUST00000026617.6
Phkg1
phosphorylase kinase gamma 1
chr5_-_86518562 0.34 ENSMUST00000140095.1
Tmprss11g
transmembrane protease, serine 11g
chr7_-_9953585 0.33 ENSMUST00000165611.1
Vmn2r48
vomeronasal 2, receptor 48

Network of associatons between targets according to the STRING database.

First level regulatory network of Hdx

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
9.0 45.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
3.8 42.3 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
2.3 13.6 GO:0038161 prolactin signaling pathway(GO:0038161)
1.1 6.4 GO:0006068 ethanol catabolic process(GO:0006068)
1.0 3.1 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
1.0 8.7 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.9 2.7 GO:0090297 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.9 6.0 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.8 3.3 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.8 3.2 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.8 2.3 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.7 4.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.7 2.0 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.6 1.9 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.6 4.8 GO:0042126 nitrate metabolic process(GO:0042126)
0.5 2.2 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.5 9.2 GO:0042448 progesterone metabolic process(GO:0042448)
0.5 7.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.5 5.9 GO:0009812 flavonoid metabolic process(GO:0009812)
0.4 3.0 GO:0006621 protein retention in ER lumen(GO:0006621)
0.4 2.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.4 0.4 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.4 3.9 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.3 3.1 GO:0009301 snRNA transcription(GO:0009301)
0.3 0.6 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.3 2.0 GO:0032790 ribosome disassembly(GO:0032790)
0.3 2.0 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.3 4.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.0 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.2 3.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.2 1.0 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.2 3.6 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 1.7 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.2 0.6 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.2 4.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.2 3.6 GO:0072189 ureter development(GO:0072189)
0.2 2.9 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.2 0.8 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318) regulation of vitamin D receptor signaling pathway(GO:0070562)
0.1 0.9 GO:1901674 histone H3-K27 acetylation(GO:0043974) leukemia inhibitory factor signaling pathway(GO:0048861) positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 1.3 GO:0016093 polyprenol metabolic process(GO:0016093)
0.1 7.6 GO:0006956 complement activation(GO:0006956)
0.1 3.6 GO:0033622 integrin activation(GO:0033622)
0.1 2.6 GO:0034063 stress granule assembly(GO:0034063)
0.1 4.4 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.1 1.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 2.7 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.1 2.1 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.1 13.0 GO:0007586 digestion(GO:0007586)
0.1 0.4 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 2.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.1 2.2 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 0.2 GO:0070343 white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.1 1.1 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.1 0.8 GO:0098719 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.9 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.1 3.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.7 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.0 0.5 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.2 GO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep(GO:0046010)
0.0 8.1 GO:0007596 blood coagulation(GO:0007596)
0.0 2.2 GO:0006940 regulation of smooth muscle contraction(GO:0006940)
0.0 0.9 GO:0060009 Sertoli cell development(GO:0060009)
0.0 2.1 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 1.0 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 1.8 GO:0048806 genitalia development(GO:0048806)
0.0 5.2 GO:0030178 negative regulation of Wnt signaling pathway(GO:0030178)
0.0 1.5 GO:0021884 forebrain neuron development(GO:0021884)
0.0 1.6 GO:0055013 cardiac muscle cell development(GO:0055013)
0.0 0.1 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 3.1 GO:0016579 protein deubiquitination(GO:0016579)
0.0 2.6 GO:0007098 centrosome cycle(GO:0007098)
0.0 1.1 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 1.5 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 4.2 GO:0031032 actomyosin structure organization(GO:0031032)
0.0 0.2 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 1.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.2 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.8 GO:0050982 detection of mechanical stimulus(GO:0050982)
0.0 0.1 GO:2000653 regulation of genetic imprinting(GO:2000653)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.1 45.1 GO:0005579 membrane attack complex(GO:0005579)
0.7 4.1 GO:0032437 cuticular plate(GO:0032437)
0.6 3.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.4 3.0 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.3 3.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.3 1.5 GO:0001674 female germ cell nucleus(GO:0001674)
0.3 7.6 GO:0044215 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.2 2.2 GO:0030478 actin cap(GO:0030478)
0.2 1.1 GO:1990130 Iml1 complex(GO:1990130)
0.2 2.0 GO:0001739 sex chromatin(GO:0001739)
0.2 0.6 GO:0032010 phagolysosome(GO:0032010)
0.2 1.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 2.1 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 2.1 GO:0031105 septin complex(GO:0031105)
0.1 0.4 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.1 2.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 2.7 GO:0042101 T cell receptor complex(GO:0042101)
0.1 3.1 GO:0005801 cis-Golgi network(GO:0005801)
0.1 8.7 GO:0072562 blood microparticle(GO:0072562)
0.1 3.6 GO:0031941 filamentous actin(GO:0031941)
0.1 0.4 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 4.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0031464 Cul2-RING ubiquitin ligase complex(GO:0031462) Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 2.6 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 6.0 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 3.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.7 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 4.0 GO:0043204 perikaryon(GO:0043204)
0.0 4.8 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 2.2 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 2.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 0.2 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 7.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 13.6 GO:0004925 prolactin receptor activity(GO:0004925)
1.6 4.8 GO:0008940 nitrate reductase activity(GO:0008940)
1.3 9.0 GO:0001851 complement component C3b binding(GO:0001851)
1.3 6.4 GO:0004062 aryl sulfotransferase activity(GO:0004062)
1.1 3.2 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.0 6.0 GO:0047035 alcohol dehydrogenase (NAD) activity(GO:0004022) testosterone dehydrogenase (NAD+) activity(GO:0047035)
1.0 7.6 GO:0001849 complement component C1q binding(GO:0001849)
0.7 2.2 GO:0030338 CMP-N-acetylneuraminate monooxygenase activity(GO:0030338)
0.7 2.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.7 3.3 GO:0015254 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.6 9.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.6 21.2 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.5 7.5 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.4 3.1 GO:0030492 hemoglobin binding(GO:0030492)
0.4 3.9 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.3 3.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 1.9 GO:0017040 ceramidase activity(GO:0017040)
0.3 2.7 GO:1901612 cardiolipin binding(GO:1901612)
0.3 2.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 1.9 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 2.0 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.2 0.9 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 4.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 0.8 GO:0036033 mediator complex binding(GO:0036033)
0.2 4.9 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.2 0.5 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.2 1.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.2 2.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 5.7 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 2.2 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 2.9 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.4 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 1.3 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 4.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.8 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 2.1 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 10.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.0 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 3.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.2 GO:0016608 growth hormone-releasing hormone activity(GO:0016608)
0.1 0.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 2.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 2.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.4 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0070403 NAD+ binding(GO:0070403)
0.0 4.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 2.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 3.1 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 2.8 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 4.1 GO:0003774 motor activity(GO:0003774)
0.0 2.9 GO:0005057 receptor signaling protein activity(GO:0005057)
0.0 0.8 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.5 GO:0004860 protein kinase inhibitor activity(GO:0004860)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 14.5 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.1 3.9 PID IL3 PATHWAY IL3-mediated signaling events
0.1 3.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.6 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.1 2.9 PID NETRIN PATHWAY Netrin-mediated signaling events
0.1 2.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 3.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 5.2 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 2.3 PID CDC42 PATHWAY CDC42 signaling events
0.0 5.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 3.2 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 1.5 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 3.2 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 53.7 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.7 9.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.7 13.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.6 7.5 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.5 6.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.5 5.9 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 3.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 2.9 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.2 3.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 2.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.2 4.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.2 3.9 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 4.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.2 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 1.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 2.2 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 1.0 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 4.6 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 2.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 2.1 REACTOME SIGNALING BY SCF KIT Genes involved in Signaling by SCF-KIT
0.0 0.4 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones