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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Gbx1_Nobox_Alx3

Z-value: 1.06

Motif logo

Transcription factors associated with Gbx1_Nobox_Alx3

Gene Symbol Gene ID Gene Info
ENSMUSG00000067724.4 gastrulation brain homeobox 1
ENSMUSG00000029736.9 NOBOX oogenesis homeobox
ENSMUSG00000014603.1 aristaless-like homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Alx3mm10_v2_chr3_+_107595031_107595164-0.221.9e-01Click!
Gbx1mm10_v2_chr5_-_24527276_245272760.048.2e-01Click!
Noboxmm10_v2_chr6_-_43307236_43307236-0.029.2e-01Click!

Activity profile of Gbx1_Nobox_Alx3 motif

Sorted Z-values of Gbx1_Nobox_Alx3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_99322943 7.06 ENSMUST00000038004.2
keratin 25
chr19_+_40089688 6.44 ENSMUST00000068094.6
ENSMUST00000080171.2
cytochrome P450, family 2, subfamily c, polypeptide 50
chr19_-_7966000 6.20 ENSMUST00000182102.1
ENSMUST00000075619.4
solute carrier family 22, member 27
chr13_+_4434306 5.93 ENSMUST00000021630.8
aldo-keto reductase family 1, member C6
chr10_+_127898515 5.44 ENSMUST00000047134.7
4short chain dehydrogenase/reductase family 9C, member 7
chr6_+_37870786 2.62 ENSMUST00000120428.1
ENSMUST00000031859.7
tripartite motif-containing 24
chr14_+_33941021 2.60 ENSMUST00000100720.1
growth differentiation factor 2
chr9_-_71163224 2.58 ENSMUST00000074465.2
aquaporin 9
chr3_+_62419668 2.31 ENSMUST00000161057.1
Rho guanine nucleotide exchange factor (GEF) 26
chr19_+_26749726 2.20 ENSMUST00000175842.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr8_-_61902669 2.00 ENSMUST00000121785.1
ENSMUST00000034057.7
palladin, cytoskeletal associated protein
chr4_+_108719649 1.91 ENSMUST00000178992.1
RIKEN cDNA 3110021N24 gene
chr1_-_72284248 1.90 ENSMUST00000097698.4
ENSMUST00000027381.6
peroxisomal trans-2-enoyl-CoA reductase
chr7_+_126950687 1.82 ENSMUST00000106333.1
seizure related 6 homolog like 2
chr2_+_20737306 1.77 ENSMUST00000114606.1
ENSMUST00000114608.1
enhancer trap locus 4
chr7_+_126950518 1.74 ENSMUST00000106335.1
ENSMUST00000146017.1
seizure related 6 homolog like 2
chr8_-_25038875 1.73 ENSMUST00000084031.4
HtrA serine peptidase 4
chr3_-_49757257 1.72 ENSMUST00000035931.7
protocadherin 18
chr5_-_62766153 1.65 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr5_-_134747241 1.51 ENSMUST00000015138.9
elastin
chr12_-_91849081 1.48 ENSMUST00000167466.1
ENSMUST00000021347.5
ENSMUST00000178462.1
sel-1 suppressor of lin-12-like (C. elegans)
chr5_-_62765618 1.46 ENSMUST00000159470.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr18_-_75697639 1.45 ENSMUST00000165559.1
CBP80/20-dependent translation initiation factor
chr11_-_99374895 1.41 ENSMUST00000006963.2
keratin 28
chrM_+_10167 1.39 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr15_-_101892916 1.36 ENSMUST00000100179.1
keratin 76
chr8_+_45658666 1.34 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
sorbin and SH3 domain containing 2
chr16_+_22918378 1.34 ENSMUST00000170805.1
fetuin beta
chr2_+_109917639 1.33 ENSMUST00000046548.7
ENSMUST00000111037.2
leucine-rich repeat-containing G protein-coupled receptor 4
chr1_-_190170671 1.31 ENSMUST00000175916.1
prospero-related homeobox 1
chr1_+_72284367 1.28 ENSMUST00000027380.5
ENSMUST00000141783.1
transmembrane protein 169
chr5_+_90561102 1.28 ENSMUST00000094615.4
RIKEN cDNA 5830473C10 gene
chrM_+_9870 1.26 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr7_+_103550368 1.25 ENSMUST00000106888.1
olfactory receptor 613
chr1_+_132298606 1.25 ENSMUST00000046071.4
kelch domain containing 8A
chr4_+_34893772 1.25 ENSMUST00000029975.3
ENSMUST00000135871.1
ENSMUST00000108130.1
glycoprotein hormones, alpha subunit
chr15_-_37459327 1.24 ENSMUST00000119730.1
ENSMUST00000120746.1
neurocalcin delta
chr19_+_39992424 1.24 ENSMUST00000049178.2
cytochrome P450, family 2. subfamily c, polypeptide 37
chr5_+_139543889 1.23 ENSMUST00000174792.1
ENSMUST00000031523.8
UNC homeobox
chr7_+_79273201 1.20 ENSMUST00000037315.6
abhydrolase domain containing 2
chr10_-_107486077 1.19 ENSMUST00000000445.1
myogenic factor 5
chr11_-_99244058 1.17 ENSMUST00000103132.3
ENSMUST00000038214.6
keratin 222
chr15_+_55307743 1.10 ENSMUST00000023053.5
ENSMUST00000110221.2
ENSMUST00000110217.3
collagen, type XIV, alpha 1
chr7_+_64501687 1.06 ENSMUST00000032732.8
amyloid beta (A4) precursor protein-binding, family A, member 2
chr18_+_56432116 1.05 ENSMUST00000070166.5
GRAM domain containing 3
chr2_-_37359274 1.02 ENSMUST00000009174.8
phosducin-like
chr1_+_161494649 1.02 ENSMUST00000086084.1
tumor necrosis factor (ligand) superfamily, member 18
chr18_+_84851338 0.98 ENSMUST00000160180.1
cytochrome b-5
chr17_-_83846769 0.97 ENSMUST00000000687.7
3-hydroxyanthranilate 3,4-dioxygenase
chr2_+_23069210 0.95 ENSMUST00000155602.1
acyl-Coenzyme A binding domain containing 5
chr3_-_79841729 0.94 ENSMUST00000168038.1
transmembrane protein 144
chr8_+_45658731 0.92 ENSMUST00000143820.1
ENSMUST00000132139.1
sorbin and SH3 domain containing 2
chr5_+_9100681 0.91 ENSMUST00000115365.1
transmembrane protein 243, mitochondrial
chrX_-_60403947 0.89 ENSMUST00000033480.6
ENSMUST00000101527.2
ATPase, class VI, type 11C
chr17_+_45734506 0.87 ENSMUST00000180558.1
RIKEN cDNA F630040K05 gene
chr1_+_74284930 0.87 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
paroxysmal nonkinesiogenic dyskinesia
chr7_-_105600103 0.87 ENSMUST00000033185.8
hemopexin
chr12_+_111814170 0.86 ENSMUST00000021714.7
zinc finger, FYVE domain containing 21
chr4_-_129261394 0.84 ENSMUST00000145261.1
expressed sequence C77080
chr3_-_32491969 0.83 ENSMUST00000164954.1
potassium large conductance calcium-activated channel, subfamily M, beta member 3
chr1_-_121332545 0.82 ENSMUST00000161068.1
insulin induced gene 2
chr10_+_39612934 0.82 ENSMUST00000019987.6
TRAF3 interacting protein 2
chrX_-_143933089 0.82 ENSMUST00000087313.3
doublecortin
chr8_+_45627709 0.81 ENSMUST00000134321.1
ENSMUST00000135336.1
sorbin and SH3 domain containing 2
chrM_+_7759 0.79 ENSMUST00000082407.1
ENSMUST00000082408.1
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr16_+_45094036 0.78 ENSMUST00000061050.5
coiled-coil domain containing 80
chr3_+_122419772 0.78 ENSMUST00000029766.4
breast cancer anti-estrogen resistance 3
chr11_-_20332654 0.77 ENSMUST00000004634.6
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr11_-_20332689 0.76 ENSMUST00000109594.1
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr15_-_37458523 0.76 ENSMUST00000116445.2
neurocalcin delta
chr6_-_130231638 0.75 ENSMUST00000088011.4
ENSMUST00000112013.1
ENSMUST00000049304.7
killer cell lectin-like receptor, subfamily A, member 7
chr5_-_137684665 0.74 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
ArfGAP with FG repeats 2
chrM_+_7005 0.73 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr5_+_135106881 0.73 ENSMUST00000005507.3
MLX interacting protein-like
chr12_-_56613270 0.73 ENSMUST00000072631.5
NK2 homeobox 9
chr2_-_116067391 0.73 ENSMUST00000140185.1
RIKEN cDNA 2700033N17 gene
chr11_-_107337556 0.73 ENSMUST00000040380.6
phosphatidylinositol transfer protein, cytoplasmic 1
chr13_-_53473074 0.73 ENSMUST00000021922.8
msh homeobox 2
chr2_-_77519565 0.72 ENSMUST00000111830.2
zinc finger protein 385B
chr11_+_99873389 0.72 ENSMUST00000093936.3
keratin associated protein 9-1
chr3_+_121291725 0.71 ENSMUST00000039442.7
asparagine-linked glycosylation 14
chr8_-_45382198 0.70 ENSMUST00000093526.6
family with sequence similarity 149, member A
chr16_+_37580137 0.69 ENSMUST00000160847.1
homogentisate 1, 2-dioxygenase
chrX_-_60893430 0.69 ENSMUST00000135107.2
SRY-box containing gene 3
chr1_-_24612700 0.68 ENSMUST00000088336.1
predicted gene 10222
chr16_-_63864114 0.68 ENSMUST00000064405.6
Eph receptor A3
chr5_-_87482258 0.68 ENSMUST00000079811.6
ENSMUST00000144144.1
UDP glucuronosyltransferase 2 family, polypeptide A1
chr2_+_69897220 0.68 ENSMUST00000055758.9
ENSMUST00000112251.2
ubiquitin protein ligase E3 component n-recognin 3
chr19_+_26750939 0.67 ENSMUST00000175953.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr7_-_45103747 0.67 ENSMUST00000003512.7
Fc receptor, IgG, alpha chain transporter
chr6_-_101377897 0.67 ENSMUST00000075994.6
PDZ domain containing RING finger 3
chr2_+_69897255 0.66 ENSMUST00000131553.1
ubiquitin protein ligase E3 component n-recognin 3
chr9_-_103222063 0.65 ENSMUST00000170904.1
transferrin
chr9_+_43829963 0.64 ENSMUST00000180221.1
predicted gene 3898
chr17_-_59013264 0.63 ENSMUST00000174122.1
ENSMUST00000025065.5
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr6_-_57535422 0.62 ENSMUST00000042766.3
protein phosphatase 1K (PP2C domain containing)
chr12_-_57546121 0.62 ENSMUST00000044380.6
forkhead box A1
chr13_-_102905740 0.62 ENSMUST00000167462.1
microtubule associated serine/threonine kinase family member 4
chr15_+_25773985 0.62 ENSMUST00000125667.1
myosin X
chr1_-_121332571 0.61 ENSMUST00000071064.6
insulin induced gene 2
chr2_+_86046451 0.61 ENSMUST00000079298.2
olfactory receptor 1034
chr11_+_94327984 0.61 ENSMUST00000107818.2
ENSMUST00000051221.6
ankyrin repeat domain 40
chr13_-_85127514 0.59 ENSMUST00000179230.1
predicted gene 4076
chr2_-_27475622 0.59 ENSMUST00000138693.1
ENSMUST00000113941.2
ENSMUST00000077737.6
bromodomain containing 3
chr2_+_155382186 0.58 ENSMUST00000134218.1
transformation related protein 53 inducible nuclear protein 2
chr10_+_127421208 0.58 ENSMUST00000168780.1
R3H domain containing 2
chr10_-_92375367 0.58 ENSMUST00000182870.1
predicted gene, 20757
chr13_+_42680565 0.58 ENSMUST00000128646.1
phosphatase and actin regulator 1
chr2_+_128591205 0.58 ENSMUST00000155430.1
predicted gene 355
chr1_-_152625212 0.57 ENSMUST00000027760.7
ral guanine nucleotide dissociation stimulator,-like 1
chr11_+_87663087 0.57 ENSMUST00000165679.1
ring finger protein 43
chr7_-_99141068 0.57 ENSMUST00000037968.8
UV radiation resistance associated gene
chr4_+_144893127 0.55 ENSMUST00000142808.1
dehydrogenase/reductase (SDR family) member 3
chr3_+_57425314 0.55 ENSMUST00000029377.7
transmembrane 4 superfamily member 4
chr2_+_116067213 0.55 ENSMUST00000152412.1
RIKEN cDNA G630016G05 gene
chr7_-_116198487 0.55 ENSMUST00000181981.1
pleckstrin homology domain containing, family A member 7
chr11_-_99521258 0.54 ENSMUST00000076948.1
keratin 39
chr18_-_3337467 0.54 ENSMUST00000154135.1
cAMP responsive element modulator
chr2_-_64975762 0.54 ENSMUST00000156765.1
growth factor receptor bound protein 14
chr14_+_73237891 0.54 ENSMUST00000044405.6
lysophosphatidic acid receptor 6
chr16_+_33684538 0.53 ENSMUST00000126532.1
HEG homolog 1 (zebrafish)
chr5_+_88583527 0.53 ENSMUST00000031229.6
RUN and FYVE domain containing 3
chr6_-_115592571 0.53 ENSMUST00000112957.1
RIKEN cDNA 2510049J12 gene
chr3_+_68572245 0.52 ENSMUST00000170788.2
schwannomin interacting protein 1
chr2_-_10130638 0.52 ENSMUST00000042290.7
inter-alpha trypsin inhibitor, heavy chain 2
chr3_+_55461758 0.52 ENSMUST00000070418.4
doublecortin-like kinase 1
chr6_-_116716888 0.52 ENSMUST00000056623.6
transmembrane protein 72
chr9_+_32116040 0.52 ENSMUST00000174641.1
Rho GTPase activating protein 32
chr1_-_190170178 0.51 ENSMUST00000177288.1
prospero-related homeobox 1
chr4_+_150853919 0.51 ENSMUST00000073600.2
ERBB receptor feedback inhibitor 1
chr13_+_94083490 0.51 ENSMUST00000156071.1
lipoma HMGIC fusion partner-like 2
chr16_+_13358375 0.50 ENSMUST00000149359.1
MKL/myocardin-like 2
chr5_+_42067960 0.50 ENSMUST00000087332.4
predicted gene 16223
chr7_+_64502090 0.50 ENSMUST00000137732.1
amyloid beta (A4) precursor protein-binding, family A, member 2
chr9_+_45138437 0.50 ENSMUST00000060125.5
sodium channel, type IV, beta
chr2_-_71750083 0.49 ENSMUST00000180494.1
predicted gene, 17250
chr10_+_127420334 0.48 ENSMUST00000171434.1
R3H domain containing 2
chrX_+_160768179 0.48 ENSMUST00000112368.2
retinoschisis (X-linked, juvenile) 1 (human)
chr1_+_177729814 0.47 ENSMUST00000016106.5
RIKEN cDNA 1700016C15 gene
chr14_-_18893623 0.47 ENSMUST00000177259.1
ubiquitin-conjugating enzyme E2E 2
chr5_+_29195983 0.47 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
ring finger protein 32
chr3_+_5218546 0.47 ENSMUST00000026284.6
zinc finger homeodomain 4
chr1_-_4360256 0.46 ENSMUST00000027032.4
retinitis pigmentosa 1 (human)
chr3_+_5218516 0.46 ENSMUST00000175866.1
zinc finger homeodomain 4
chr14_-_36919314 0.46 ENSMUST00000182797.1
coiled-coil serine rich 2
chr6_-_126645784 0.46 ENSMUST00000055168.3
potassium voltage-gated channel, shaker-related subfamily, member 1
chr6_-_136171722 0.45 ENSMUST00000053880.6
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr1_+_82233112 0.43 ENSMUST00000023262.5
predicted gene 9747
chr7_+_126950837 0.43 ENSMUST00000106332.1
seizure related 6 homolog like 2
chr16_-_37384915 0.43 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
syntaxin binding protein 5-like
chr4_-_63154130 0.43 ENSMUST00000030041.4
alpha 1 microglobulin/bikunin
chr15_-_11037968 0.43 ENSMUST00000058007.5
relaxin family peptide receptor 3
chr17_+_45506825 0.43 ENSMUST00000024733.7
alanyl-tRNA synthetase 2, mitochondrial (putative)
chr15_-_33687840 0.43 ENSMUST00000042021.3
testis-specific protein, Y-encoded-like 5
chr1_-_155417394 0.42 ENSMUST00000111775.1
ENSMUST00000111774.1
xenotropic and polytropic retrovirus receptor 1
chr3_+_86070915 0.42 ENSMUST00000182666.1
SH3 domain protein D19
chr10_+_127421124 0.42 ENSMUST00000170336.1
R3H domain containing 2
chr18_-_3337614 0.41 ENSMUST00000150235.1
ENSMUST00000154470.1
cAMP responsive element modulator
chr18_-_3281036 0.41 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
cAMP responsive element modulator
chr14_-_18893376 0.41 ENSMUST00000151926.1
ubiquitin-conjugating enzyme E2E 2
chrX_+_107255878 0.40 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
G protein-coupled receptor 174
chr11_+_70166623 0.40 ENSMUST00000102571.3
ENSMUST00000178945.1
ENSMUST00000000327.6
C-type lectin domain family 10, member A
chr8_-_84846860 0.40 ENSMUST00000003912.6
calreticulin
chr17_-_49564262 0.40 ENSMUST00000057610.6
dishevelled associated activator of morphogenesis 2
chr17_-_35697971 0.40 ENSMUST00000146472.1
discoidin domain receptor family, member 1
chr2_-_134554348 0.39 ENSMUST00000028704.2
hydroxyacid oxidase 1, liver
chr6_+_8948608 0.38 ENSMUST00000160300.1
neurexophilin 1
chr5_+_81021202 0.38 ENSMUST00000117253.1
ENSMUST00000120128.1
latrophilin 3
chr18_-_3337539 0.38 ENSMUST00000142690.1
ENSMUST00000025069.4
ENSMUST00000082141.5
ENSMUST00000165086.1
ENSMUST00000149803.1
cAMP responsive element modulator
chr3_+_121967822 0.38 ENSMUST00000137089.1
Rho GTPase activating protein 29
chr11_-_99521336 0.37 ENSMUST00000107445.1
keratin 39
chr15_-_67113909 0.37 ENSMUST00000092640.5
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr6_+_15196949 0.37 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
forkhead box P2
chr8_-_67818218 0.36 ENSMUST00000059374.4
pleckstrin and Sec7 domain containing 3
chr10_+_73821937 0.35 ENSMUST00000134009.2
ENSMUST00000125006.2
ENSMUST00000177420.1
protocadherin 15
chr11_+_29718563 0.35 ENSMUST00000060992.5
reticulon 4
chr8_-_67818284 0.34 ENSMUST00000120071.1
pleckstrin and Sec7 domain containing 3
chr11_+_23306884 0.34 ENSMUST00000180046.1
ubiquitin specific peptidase 34
chr6_+_145934113 0.34 ENSMUST00000032383.7
sarcospan
chr6_-_147264124 0.34 ENSMUST00000052296.6
parathyroid hormone-like peptide
chr18_-_38284391 0.34 ENSMUST00000025311.5
protocadherin 12
chr1_-_172632931 0.33 ENSMUST00000027826.5
dual specificity phosphatase 23
chr6_-_148831395 0.33 ENSMUST00000145960.1
importin 8
chr6_+_34746368 0.33 ENSMUST00000142716.1
caldesmon 1
chr11_-_43901187 0.32 ENSMUST00000067258.2
ENSMUST00000139906.1
adrenergic receptor, alpha 1b
chr12_-_83921809 0.32 ENSMUST00000135962.1
ENSMUST00000155112.1
ENSMUST00000136848.1
ENSMUST00000126943.1
numb gene homolog (Drosophila)
chr7_+_125829653 0.32 ENSMUST00000124223.1
RIKEN cDNA D430042O09 gene
chr11_+_94328242 0.32 ENSMUST00000021227.5
ankyrin repeat domain 40
chr11_+_70166696 0.32 ENSMUST00000178567.1
C-type lectin domain family 10, member A
chr11_-_99337930 0.32 ENSMUST00000100482.2
keratin 26
chr1_+_104768510 0.32 ENSMUST00000062528.8
cadherin 20
chr8_-_84662841 0.31 ENSMUST00000060427.4
immediate early response 2
chr4_-_14621669 0.31 ENSMUST00000143105.1
solute carrier family 26, member 7
chr7_+_19228334 0.31 ENSMUST00000063976.8
optic atrophy 3
chrM_+_2743 0.30 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr1_-_92518515 0.30 ENSMUST00000062353.4
olfactory receptor 1414
chr9_-_67539392 0.30 ENSMUST00000039662.8
talin 2
chrX_-_143933204 0.30 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
doublecortin
chr3_+_93393696 0.30 ENSMUST00000045912.2
repetin
chr7_+_30458280 0.30 ENSMUST00000126297.1
nephrosis 1, nephrin

Network of associatons between targets according to the STRING database.

First level regulatory network of Gbx1_Nobox_Alx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.6 2.6 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.6 1.8 GO:0061114 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.6 6.4 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.4 1.3 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.4 6.2 GO:0015747 urate transport(GO:0015747)
0.4 1.5 GO:0015825 L-serine transport(GO:0015825)
0.4 2.6 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.3 1.0 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.3 1.0 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.3 0.3 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.3 1.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3 2.9 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.2 0.7 GO:0035880 embryonic nail plate morphogenesis(GO:0035880) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.2 0.7 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.2 0.6 GO:0061144 alveolar secondary septum development(GO:0061144)
0.2 0.6 GO:0030862 neuroblast division in subventricular zone(GO:0021849) positive regulation of polarized epithelial cell differentiation(GO:0030862)
0.2 0.5 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 0.9 GO:0015886 heme transport(GO:0015886)
0.2 6.7 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.2 1.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.2 0.5 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.2 0.6 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.2 0.6 GO:0006742 NADP catabolic process(GO:0006742)
0.2 1.1 GO:0030242 pexophagy(GO:0030242)
0.1 0.6 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.7 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 2.6 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 4.0 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 0.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.7 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 1.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.5 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.4 GO:0060809 mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.1 1.4 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 1.9 GO:0030497 fatty acid elongation(GO:0030497)
0.1 1.4 GO:0048733 sebaceous gland development(GO:0048733)
0.1 0.7 GO:0009757 carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255) negative regulation of oxidative phosphorylation(GO:0090324)
0.1 1.0 GO:0046874 quinolinate metabolic process(GO:0046874)
0.1 0.7 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
0.1 0.2 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.1 0.5 GO:0050975 sensory perception of touch(GO:0050975)
0.1 0.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.1 0.9 GO:0002329 pre-B cell differentiation(GO:0002329)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.3 GO:0001982 baroreceptor response to decreased systemic arterial blood pressure(GO:0001982) norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.1 1.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 2.0 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.5 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 0.4 GO:0009441 glycolate metabolic process(GO:0009441)
0.1 1.3 GO:0006590 thyroid hormone generation(GO:0006590) follicle-stimulating hormone secretion(GO:0046884)
0.1 0.3 GO:1903860 negative regulation of dendrite extension(GO:1903860)
0.1 0.6 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 0.6 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1 2.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.4 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.1 0.8 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.2 GO:0032570 response to progesterone(GO:0032570)
0.1 1.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1 1.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.1 0.2 GO:0090172 microtubule cytoskeleton organization involved in homologous chromosome segregation(GO:0090172)
0.1 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.1 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.7 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.1 0.3 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 3.0 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 1.5 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.5 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0061325 cell proliferation involved in outflow tract morphogenesis(GO:0061325)
0.0 0.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 2.0 GO:0097178 ruffle assembly(GO:0097178)
0.0 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 1.2 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.4 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.3 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.7 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.9 GO:0034219 carbohydrate transmembrane transport(GO:0034219)
0.0 0.3 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.3 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.3 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0006667 sphinganine metabolic process(GO:0006667)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 1.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.1 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.0 0.1 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.4 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.2 GO:1903140 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.0 0.8 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.9 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.3 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.1 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 1.9 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.8 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.7 GO:0021854 hypothalamus development(GO:0021854)
0.0 1.2 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.5 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.0 0.5 GO:0001553 luteinization(GO:0001553)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.0 0.1 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.1 GO:0097283 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.9 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.2 GO:2000121 elastic fiber assembly(GO:0048251) regulation of removal of superoxide radicals(GO:2000121)
0.0 0.1 GO:1904578 response to thapsigargin(GO:1904578) cellular response to thapsigargin(GO:1904579)
0.0 0.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.0 GO:0060618 nipple development(GO:0060618)
0.0 0.4 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.3 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.2 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.4 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 1.5 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.1 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.4 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.4 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.0 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.0 0.1 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.3 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.5 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.4 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0071953 elastic fiber(GO:0071953)
0.4 2.6 GO:0005726 perichromatin fibrils(GO:0005726)
0.3 1.5 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.2 1.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.2 2.9 GO:0071564 npBAF complex(GO:0071564)
0.1 1.2 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 11.7 GO:0005882 intermediate filament(GO:0005882)
0.1 1.0 GO:0005915 zonula adherens(GO:0005915)
0.1 1.9 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.7 GO:0097433 dense body(GO:0097433)
0.1 0.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.4 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 2.0 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.5 GO:0097542 ciliary tip(GO:0097542)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 1.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.5 GO:0043083 synaptic cleft(GO:0043083)
0.0 1.3 GO:0070469 respiratory chain(GO:0070469)
0.0 0.1 GO:0055087 Ski complex(GO:0055087)
0.0 0.1 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 2.2 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 2.2 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.3 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.1 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.2 GO:0071437 invadopodium(GO:0071437)
0.0 0.4 GO:0001533 cornified envelope(GO:0001533)
0.0 1.6 GO:0072562 blood microparticle(GO:0072562)
0.0 1.8 GO:0001650 fibrillar center(GO:0001650)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 5.9 GO:0047006 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006)
1.6 6.4 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.6 1.9 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.5 2.6 GO:0005350 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.4 6.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.4 2.6 GO:0034056 estrogen response element binding(GO:0034056)
0.3 5.8 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.2 0.9 GO:0015232 heme transporter activity(GO:0015232)
0.2 1.5 GO:0022858 L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.1 0.9 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.5 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.7 GO:0019770 IgG receptor activity(GO:0019770)
0.1 1.0 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 1.8 GO:0050693 LBD domain binding(GO:0050693)
0.1 1.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.1 3.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.4 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1 0.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.4 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.6 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 1.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 0.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.4 GO:0004966 galanin receptor activity(GO:0004966)
0.1 1.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 0.3 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.1 1.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.5 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.3 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 1.7 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 3.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.5 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.3 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.1 1.7 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 2.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.3 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.3 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 1.2 GO:0070330 aromatase activity(GO:0070330)
0.0 0.4 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 2.7 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.0 2.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.2 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 1.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.9 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 1.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.8 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.5 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 1.4 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.9 GO:1901476 carbohydrate transmembrane transporter activity(GO:0015144) carbohydrate transporter activity(GO:1901476)
0.0 0.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 1.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 8.0 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.2 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.0 GO:0019809 spermidine binding(GO:0019809)
0.0 0.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.2 GO:0070410 JUN kinase binding(GO:0008432) co-SMAD binding(GO:0070410)
0.0 0.4 GO:0050681 androgen receptor binding(GO:0050681)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.0 PID ARF6 PATHWAY Arf6 signaling events
0.1 2.6 PID ALK1 PATHWAY ALK1 signaling events
0.1 5.5 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.9 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.1 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.3 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.0 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.7 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.0 0.4 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.6 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.2 1.3 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 2.0 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 2.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 1.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 1.0 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.1 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.3 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.1 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 0.5 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 3.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.8 REACTOME G ALPHA1213 SIGNALLING EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME OPSINS Genes involved in Opsins