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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Foxd1

Z-value: 1.35

Motif logo

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Transcription factors associated with Foxd1

Gene Symbol Gene ID Gene Info
Foxd1
ENSMUSG00000078302.3 forkhead box D1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxd1mm10_v2_chr13_+_98354234_983542500.202.4e-01Click!

Activity profile of Foxd1 motif

Sorted Z-values of Foxd1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_138170992 6.42 ENSMUST00000139983.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr11_-_102365111 6.11 ENSMUST00000006749.9
Slc4a1
solute carrier family 4 (anion exchanger), member 1
chr8_+_70373541 6.05 ENSMUST00000003659.7
Comp
cartilage oligomeric matrix protein
chr5_-_138171248 5.87 ENSMUST00000153867.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr5_-_138171216 5.56 ENSMUST00000147920.1
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr7_+_110772604 5.54 ENSMUST00000005829.6
Ampd3
adenosine monophosphate deaminase 3
chr15_+_80623499 5.39 ENSMUST00000043149.7
Grap2
GRB2-related adaptor protein 2
chr11_+_74619594 5.26 ENSMUST00000100866.2
E130309D14Rik
RIKEN cDNA E130309D14 gene
chr8_-_85380964 5.11 ENSMUST00000122452.1
Mylk3
myosin light chain kinase 3
chr10_+_115817247 4.33 ENSMUST00000035563.7
ENSMUST00000080630.3
ENSMUST00000179196.1
Tspan8
tetraspanin 8
chr4_+_134315112 4.18 ENSMUST00000105875.1
ENSMUST00000030638.6
Trim63
tripartite motif-containing 63
chr6_+_30541582 4.16 ENSMUST00000096066.4
Cpa2
carboxypeptidase A2, pancreatic
chr15_+_35296090 4.09 ENSMUST00000022952.4
Osr2
odd-skipped related 2
chr2_-_84822546 4.08 ENSMUST00000028471.5
Smtnl1
smoothelin-like 1
chr14_+_27000362 4.01 ENSMUST00000035433.8
Hesx1
homeobox gene expressed in ES cells
chrX_+_164140447 3.85 ENSMUST00000073973.4
Ace2
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr11_+_69095217 3.57 ENSMUST00000101004.2
Per1
period circadian clock 1
chr4_+_11191726 3.23 ENSMUST00000029866.9
ENSMUST00000108324.3
Ccne2
cyclin E2
chr3_-_52104891 3.19 ENSMUST00000121440.1
Maml3
mastermind like 3 (Drosophila)
chr19_+_58759700 3.17 ENSMUST00000026081.3
Pnliprp2
pancreatic lipase-related protein 2
chr3_-_27153782 3.12 ENSMUST00000175857.1
ENSMUST00000177055.1
ENSMUST00000176535.1
Ect2
ect2 oncogene
chr9_+_96196246 3.07 ENSMUST00000165120.2
ENSMUST00000034982.9
Tfdp2
transcription factor Dp 2
chr6_-_83536215 2.91 ENSMUST00000075161.5
Actg2
actin, gamma 2, smooth muscle, enteric
chr15_-_58324161 2.81 ENSMUST00000022985.1
Klhl38
kelch-like 38
chr2_+_14873656 2.79 ENSMUST00000114718.1
ENSMUST00000114719.1
Cacnb2
calcium channel, voltage-dependent, beta 2 subunit
chr3_-_27153844 2.79 ENSMUST00000176242.2
ENSMUST00000176780.1
Ect2
ect2 oncogene
chr16_-_76022266 2.70 ENSMUST00000114240.1
Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
chr17_+_47505211 2.70 ENSMUST00000182935.1
ENSMUST00000182506.1
Ccnd3
cyclin D3
chr17_+_47505149 2.70 ENSMUST00000183177.1
ENSMUST00000182848.1
Ccnd3
cyclin D3
chr6_+_142298419 2.67 ENSMUST00000041993.2
Iapp
islet amyloid polypeptide
chr17_+_47505043 2.66 ENSMUST00000182129.1
ENSMUST00000171031.1
Ccnd3
cyclin D3
chr17_+_47505117 2.66 ENSMUST00000183044.1
ENSMUST00000037333.10
Ccnd3
cyclin D3
chr3_-_27153861 2.62 ENSMUST00000108300.1
ENSMUST00000108298.2
Ect2
ect2 oncogene
chr15_+_79348061 2.52 ENSMUST00000163691.1
Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr17_+_47505073 2.51 ENSMUST00000183210.1
Ccnd3
cyclin D3
chr13_-_98815408 2.45 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
Fcho2
FCH domain only 2
chr15_+_79347534 2.34 ENSMUST00000096350.3
Maff
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr11_+_3330781 2.32 ENSMUST00000136536.1
ENSMUST00000093399.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr3_+_27154020 2.22 ENSMUST00000181124.1
1700125G22Rik
RIKEN cDNA 1700125G22 gene
chr4_+_11191354 2.17 ENSMUST00000170901.1
Ccne2
cyclin E2
chr1_-_45503282 2.14 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr5_-_149051300 2.14 ENSMUST00000110505.1
Hmgb1
high mobility group box 1
chr7_-_115824699 2.04 ENSMUST00000169129.1
Sox6
SRY-box containing gene 6
chr14_-_70766598 2.01 ENSMUST00000167242.1
ENSMUST00000022696.6
Xpo7
exportin 7
chr12_+_95695350 1.88 ENSMUST00000110117.1
Flrt2
fibronectin leucine rich transmembrane protein 2
chr2_+_112265809 1.87 ENSMUST00000110991.2
Slc12a6
solute carrier family 12, member 6
chr11_+_96929367 1.86 ENSMUST00000062172.5
Prr15l
proline rich 15-like
chr11_+_3330401 1.84 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr14_+_11227511 1.83 ENSMUST00000080237.3
Rpl21-ps4
ribosomal protein L21, pseudogene 4
chr13_-_51701041 1.77 ENSMUST00000110042.1
Gm15440
predicted gene 15440
chr2_-_163645125 1.77 ENSMUST00000017851.3
Serinc3
serine incorporator 3
chr13_+_104178797 1.71 ENSMUST00000022225.5
ENSMUST00000069187.5
Trim23
tripartite motif-containing 23
chrX_-_7740206 1.68 ENSMUST00000128289.1
Ccdc120
coiled-coil domain containing 120
chr11_+_101733011 1.67 ENSMUST00000129741.1
Dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr1_+_12718496 1.66 ENSMUST00000088585.3
Sulf1
sulfatase 1
chr11_+_3332426 1.63 ENSMUST00000136474.1
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr9_+_78615501 1.63 ENSMUST00000093812.4
Cd109
CD109 antigen
chr18_-_47333311 1.63 ENSMUST00000126684.1
ENSMUST00000156422.1
Sema6a
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chrX_+_68678712 1.63 ENSMUST00000114654.1
ENSMUST00000114655.1
ENSMUST00000114657.2
ENSMUST00000114653.1
Fmr1
fragile X mental retardation syndrome 1
chr15_+_61985540 1.61 ENSMUST00000159327.1
ENSMUST00000167731.1
Myc
myelocytomatosis oncogene
chr19_-_41848076 1.60 ENSMUST00000059231.2
Frat2
frequently rearranged in advanced T cell lymphomas 2
chr15_+_61985377 1.60 ENSMUST00000161976.1
ENSMUST00000022971.7
Myc
myelocytomatosis oncogene
chr16_-_74411292 1.59 ENSMUST00000117200.1
Robo2
roundabout homolog 2 (Drosophila)
chr3_+_138860489 1.59 ENSMUST00000121826.1
Tspan5
tetraspanin 5
chr12_+_71016658 1.56 ENSMUST00000125125.1
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr3_-_93015669 1.55 ENSMUST00000107301.1
ENSMUST00000029521.4
Crct1
cysteine-rich C-terminal 1
chr4_-_47010781 1.54 ENSMUST00000135777.1
Gm568
predicted gene 568
chr19_+_53329413 1.53 ENSMUST00000025998.7
Mxi1
Max interacting protein 1
chr15_-_51991679 1.51 ENSMUST00000022927.9
Rad21
RAD21 homolog (S. pombe)
chr15_+_97784355 1.46 ENSMUST00000117892.1
Slc48a1
solute carrier family 48 (heme transporter), member 1
chr6_-_148946146 1.42 ENSMUST00000132696.1
Fam60a
family with sequence similarity 60, member A
chr8_-_84197667 1.41 ENSMUST00000181282.1
Gm26887
predicted gene, 26887
chr5_-_122988533 1.40 ENSMUST00000086200.4
ENSMUST00000156474.1
Kdm2b
lysine (K)-specific demethylase 2B
chrX_+_68678541 1.38 ENSMUST00000088546.5
Fmr1
fragile X mental retardation syndrome 1
chr11_+_101732950 1.37 ENSMUST00000039152.7
Dhx8
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr2_+_52072823 1.32 ENSMUST00000112693.2
ENSMUST00000069794.5
Rif1
Rap1 interacting factor 1 homolog (yeast)
chrX_+_35888808 1.32 ENSMUST00000033419.6
Dock11
dedicator of cytokinesis 11
chr19_-_7341848 1.32 ENSMUST00000171393.1
Mark2
MAP/microtubule affinity-regulating kinase 2
chr5_-_149051604 1.29 ENSMUST00000093196.4
Hmgb1
high mobility group box 1
chr4_+_138725282 1.29 ENSMUST00000030530.4
ENSMUST00000124660.1
Pla2g2c
phospholipase A2, group IIC
chr6_+_135362931 1.23 ENSMUST00000032330.9
Emp1
epithelial membrane protein 1
chr11_+_96929260 1.23 ENSMUST00000054311.5
ENSMUST00000107636.3
Prr15l
proline rich 15-like
chr5_+_25246775 1.21 ENSMUST00000144971.1
Galnt11
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chrX_+_42149288 1.20 ENSMUST00000115073.2
ENSMUST00000115072.1
Stag2
stromal antigen 2
chr11_+_34047115 1.19 ENSMUST00000109329.1
ENSMUST00000169878.2
Lcp2
lymphocyte cytosolic protein 2
chr1_+_134415378 1.17 ENSMUST00000027727.8
Adipor1
adiponectin receptor 1
chr15_+_54410755 1.17 ENSMUST00000036737.3
Colec10
collectin sub-family member 10
chr15_-_97831460 1.17 ENSMUST00000079838.7
ENSMUST00000118294.1
Hdac7
histone deacetylase 7
chr13_+_55445301 1.17 ENSMUST00000001115.8
ENSMUST00000099482.3
Grk6
G protein-coupled receptor kinase 6
chr19_-_28010995 1.14 ENSMUST00000172907.1
ENSMUST00000046898.9
Rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr5_-_122989086 1.14 ENSMUST00000046073.9
Kdm2b
lysine (K)-specific demethylase 2B
chr6_+_52177498 1.12 ENSMUST00000070587.3
5730596B20Rik
RIKEN cDNA 5730596B20 gene
chr14_-_110755100 1.12 ENSMUST00000078386.2
Slitrk6
SLIT and NTRK-like family, member 6
chrX_+_68678624 1.07 ENSMUST00000114656.1
Fmr1
fragile X mental retardation syndrome 1
chr2_+_128126030 1.06 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
Bcl2l11
BCL2-like 11 (apoptosis facilitator)
chr5_+_14025305 1.06 ENSMUST00000073957.6
Sema3e
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr4_+_133130505 1.04 ENSMUST00000084241.5
ENSMUST00000138831.1
Wasf2
WAS protein family, member 2
chr19_-_7341792 1.04 ENSMUST00000164205.1
ENSMUST00000165286.1
ENSMUST00000168324.1
ENSMUST00000032557.8
Mark2
MAP/microtubule affinity-regulating kinase 2
chr12_-_111980751 1.03 ENSMUST00000170525.1
BC048943
cDNA sequence BC048943
chr5_-_122989260 1.03 ENSMUST00000118027.1
Kdm2b
lysine (K)-specific demethylase 2B
chr11_-_33147400 1.03 ENSMUST00000020507.7
Fgf18
fibroblast growth factor 18
chr5_+_31251678 1.01 ENSMUST00000054829.7
ENSMUST00000114570.1
ENSMUST00000075611.7
Krtcap3
keratinocyte associated protein 3
chr11_-_120990871 1.01 ENSMUST00000154483.1
Csnk1d
casein kinase 1, delta
chr2_-_60125651 1.01 ENSMUST00000112550.1
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr16_-_22439570 1.01 ENSMUST00000170393.1
Etv5
ets variant gene 5
chr5_-_147307264 0.99 ENSMUST00000031650.3
Cdx2
caudal type homeobox 2
chr2_-_33431324 0.99 ENSMUST00000113158.1
Zbtb34
zinc finger and BTB domain containing 34
chr8_+_34807287 0.97 ENSMUST00000033930.4
Dusp4
dual specificity phosphatase 4
chr2_-_72813665 0.96 ENSMUST00000136807.1
ENSMUST00000148327.1
6430710C18Rik
RIKEN cDNA 6430710C18 gene
chr1_+_179546303 0.96 ENSMUST00000040706.8
Cnst
consortin, connexin sorting protein
chr3_+_134236483 0.95 ENSMUST00000181904.1
ENSMUST00000053048.9
Cxxc4
CXXC finger 4
chr1_+_134415414 0.95 ENSMUST00000112237.1
Adipor1
adiponectin receptor 1
chr11_-_107348130 0.95 ENSMUST00000134763.1
Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr13_+_75089826 0.95 ENSMUST00000022075.4
Pcsk1
proprotein convertase subtilisin/kexin type 1
chr7_+_75455534 0.94 ENSMUST00000147005.1
ENSMUST00000166315.1
Akap13
A kinase (PRKA) anchor protein 13
chr5_+_3928033 0.93 ENSMUST00000143365.1
Akap9
A kinase (PRKA) anchor protein (yotiao) 9
chr7_+_126776939 0.93 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
Ypel3
yippee-like 3 (Drosophila)
chr6_-_52158292 0.92 ENSMUST00000000964.5
ENSMUST00000120363.1
Hoxa1
homeobox A1
chrX_+_101254528 0.92 ENSMUST00000062000.4
Foxo4
forkhead box O4
chr2_-_152398046 0.92 ENSMUST00000063332.8
ENSMUST00000182625.1
Sox12
SRY-box containing gene 12
chr4_+_101507947 0.90 ENSMUST00000149047.1
ENSMUST00000106929.3
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr8_+_20136455 0.90 ENSMUST00000179299.1
ENSMUST00000096485.4
Gm21811
predicted gene, 21811
chr1_-_54926311 0.89 ENSMUST00000179030.1
ENSMUST00000044359.9
Ankrd44
ankyrin repeat domain 44
chr17_-_65884902 0.86 ENSMUST00000024905.9
Ralbp1
ralA binding protein 1
chr19_-_7341433 0.86 ENSMUST00000165965.1
ENSMUST00000051711.9
ENSMUST00000169541.1
ENSMUST00000165989.1
Mark2
MAP/microtubule affinity-regulating kinase 2
chr4_+_132564051 0.85 ENSMUST00000070690.7
Ptafr
platelet-activating factor receptor
chr7_+_19359740 0.84 ENSMUST00000140836.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr7_-_29505447 0.84 ENSMUST00000183096.1
ENSMUST00000085809.4
Sipa1l3
signal-induced proliferation-associated 1 like 3
chr4_+_155791172 0.84 ENSMUST00000105593.1
Ankrd65
ankyrin repeat domain 65
chr15_-_96460838 0.83 ENSMUST00000047835.6
Scaf11
SR-related CTD-associated factor 11
chr2_-_104028287 0.83 ENSMUST00000056170.3
4931422A03Rik
RIKEN cDNA 4931422A03 gene
chr12_+_38781093 0.83 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr16_+_25286810 0.82 ENSMUST00000056087.3
Tprg
transformation related protein 63 regulated
chr3_-_102964124 0.81 ENSMUST00000058899.8
Nr1h5
nuclear receptor subfamily 1, group H, member 5
chr4_-_128806045 0.81 ENSMUST00000106072.2
ENSMUST00000170934.1
Zfp362
zinc finger protein 362
chr7_-_126776818 0.81 ENSMUST00000068836.4
Gm9967
predicted gene 9967
chr4_-_59549243 0.81 ENSMUST00000173699.1
ENSMUST00000173884.1
ENSMUST00000102883.4
ENSMUST00000174586.1
Ptbp3
polypyrimidine tract binding protein 3
chr3_+_96557950 0.80 ENSMUST00000074519.6
ENSMUST00000049093.7
Txnip
thioredoxin interacting protein
chr10_+_53596936 0.79 ENSMUST00000020004.6
Asf1a
ASF1 anti-silencing function 1 homolog A (S. cerevisiae)
chr11_+_120232921 0.78 ENSMUST00000122148.1
ENSMUST00000044985.7
Bahcc1
BAH domain and coiled-coil containing 1
chr14_-_93888732 0.78 ENSMUST00000068992.2
Pcdh9
protocadherin 9
chr2_-_73312701 0.77 ENSMUST00000058615.9
Cir1
corepressor interacting with RBPJ, 1
chr13_-_93499803 0.76 ENSMUST00000065537.7
Jmy
junction-mediating and regulatory protein
chr1_+_55131253 0.76 ENSMUST00000027122.7
Mob4
MOB family member 4, phocein
chr5_+_21372642 0.76 ENSMUST00000035799.5
Fgl2
fibrinogen-like protein 2
chr4_+_136357423 0.75 ENSMUST00000182167.1
Gm17388
predicted gene, 17388
chr8_+_19682268 0.75 ENSMUST00000153710.1
ENSMUST00000127799.1
Gm6483
predicted gene 6483
chr5_+_107437908 0.75 ENSMUST00000094541.2
Btbd8
BTB (POZ) domain containing 8
chr18_-_34624562 0.73 ENSMUST00000003876.3
ENSMUST00000115766.1
ENSMUST00000097626.3
ENSMUST00000115765.1
Brd8
bromodomain containing 8
chr13_+_118714678 0.73 ENSMUST00000022246.8
Fgf10
fibroblast growth factor 10
chr12_-_15816762 0.73 ENSMUST00000020922.7
Trib2
tribbles homolog 2 (Drosophila)
chr7_-_142372210 0.72 ENSMUST00000084412.5
Ifitm10
interferon induced transmembrane protein 10
chr13_-_78196373 0.72 ENSMUST00000125176.2
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr5_+_86804508 0.72 ENSMUST00000038384.7
Ythdc1
YTH domain containing 1
chr8_-_36953139 0.70 ENSMUST00000179501.1
Dlc1
deleted in liver cancer 1
chr1_+_55131317 0.70 ENSMUST00000162553.1
Mob4
MOB family member 4, phocein
chr11_-_102556122 0.69 ENSMUST00000143842.1
Gpatch8
G patch domain containing 8
chr4_+_101507855 0.66 ENSMUST00000038207.5
Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chrX_+_151521146 0.66 ENSMUST00000112670.1
ENSMUST00000046962.4
ENSMUST00000112668.2
ENSMUST00000046950.6
Phf8
PHD finger protein 8
chr6_+_29853746 0.66 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr5_-_73632421 0.65 ENSMUST00000087177.2
Lrrc66
leucine rich repeat containing 66
chr8_+_20567716 0.65 ENSMUST00000178995.1
Gm21092
predicted gene, 21092
chr2_+_26973416 0.65 ENSMUST00000014996.7
ENSMUST00000102891.3
Adamts13
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
chr3_-_61365951 0.65 ENSMUST00000066298.2
B430305J03Rik
RIKEN cDNA B430305J03 gene
chrX_+_151520655 0.60 ENSMUST00000112666.1
ENSMUST00000168501.1
ENSMUST00000112662.2
Phf8
PHD finger protein 8
chr8_+_65618009 0.59 ENSMUST00000110258.1
ENSMUST00000110256.1
ENSMUST00000110255.1
March1
membrane-associated ring finger (C3HC4) 1
chr6_-_5496296 0.58 ENSMUST00000019721.4
Pdk4
pyruvate dehydrogenase kinase, isoenzyme 4
chr12_-_100725028 0.58 ENSMUST00000043599.6
Rps6ka5
ribosomal protein S6 kinase, polypeptide 5
chr7_-_25788635 0.57 ENSMUST00000002677.4
ENSMUST00000085948.4
Axl
AXL receptor tyrosine kinase
chr12_+_52699297 0.57 ENSMUST00000095737.3
Akap6
A kinase (PRKA) anchor protein 6
chr12_+_38780817 0.55 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr19_-_45783512 0.55 ENSMUST00000026243.3
Mgea5
meningioma expressed antigen 5 (hyaluronidase)
chrX_+_42149534 0.53 ENSMUST00000127618.1
Stag2
stromal antigen 2
chr6_-_99096196 0.53 ENSMUST00000175886.1
Foxp1
forkhead box P1
chr9_-_108649349 0.52 ENSMUST00000013338.8
Arih2
ariadne homolog 2 (Drosophila)
chr8_-_35495487 0.51 ENSMUST00000033927.6
Eri1
exoribonuclease 1
chr18_-_39489880 0.50 ENSMUST00000152853.1
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr2_+_122028544 0.50 ENSMUST00000028668.7
Eif3j1
eukaryotic translation initiation factor 3, subunit J1
chr1_+_40681659 0.49 ENSMUST00000027231.7
Slc9a2
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr6_+_6248659 0.49 ENSMUST00000181633.1
ENSMUST00000176283.1
ENSMUST00000175814.1
ENSMUST00000181192.1
Gm20619
predicted gene 20619
chr5_+_86804214 0.48 ENSMUST00000119339.1
ENSMUST00000120498.1
Ythdc1
YTH domain containing 1
chr3_+_129532386 0.48 ENSMUST00000071402.2
Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr12_+_69296676 0.48 ENSMUST00000021362.4
Klhdc2
kelch domain containing 2
chr2_+_18064645 0.48 ENSMUST00000114680.2
Mllt10
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr19_-_28011138 0.47 ENSMUST00000174850.1
Rfx3
regulatory factor X, 3 (influences HLA class II expression)
chr7_+_24907618 0.46 ENSMUST00000151121.1
Arhgef1
Rho guanine nucleotide exchange factor (GEF) 1
chr11_-_120086790 0.46 ENSMUST00000106227.1
ENSMUST00000106229.1
ENSMUST00000180242.1
Azi1
5-azacytidine induced gene 1
chr19_+_30030589 0.45 ENSMUST00000112552.1
Uhrf2
ubiquitin-like, containing PHD and RING finger domains 2
chr7_-_142061021 0.44 ENSMUST00000084418.2
Mob2
MOB kinase activator 2
chr11_-_54956047 0.41 ENSMUST00000155316.1
ENSMUST00000108889.3
ENSMUST00000126703.1
Tnip1
TNFAIP3 interacting protein 1
chr1_-_64956731 0.39 ENSMUST00000123225.1
Plekhm3
pleckstrin homology domain containing, family M, member 3
chr8_+_31091593 0.38 ENSMUST00000161713.1
Dusp26
dual specificity phosphatase 26 (putative)
chr15_+_6422240 0.37 ENSMUST00000163082.1
Dab2
disabled 2, mitogen-responsive phosphoprotein
chr4_+_32238950 0.37 ENSMUST00000037416.6
Bach2
BTB and CNC homology 2
chr6_-_39725193 0.37 ENSMUST00000101497.3
Braf
Braf transforming gene
chr11_+_98741871 0.37 ENSMUST00000103139.4
Thra
thyroid hormone receptor alpha
chr11_+_43433720 0.36 ENSMUST00000126128.1
ENSMUST00000151880.1
ENSMUST00000020681.3
Slu7
SLU7 splicing factor homolog (S. cerevisiae)
chr6_-_88874597 0.36 ENSMUST00000061262.4
ENSMUST00000140455.1
ENSMUST00000145780.1
Podxl2
podocalyxin-like 2
chr2_-_71367749 0.36 ENSMUST00000151937.1
Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr7_+_82175156 0.35 ENSMUST00000180243.1
Sh3gl3
SH3-domain GRB2-like 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxd1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 17.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
1.4 4.1 GO:0099547 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
1.1 3.4 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
1.0 3.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
1.0 4.1 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
1.0 3.8 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.9 2.8 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.9 5.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.8 5.8 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.8 3.2 GO:0090094 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.7 3.6 GO:0021993 initiation of neural tube closure(GO:0021993)
0.7 3.6 GO:0097167 circadian regulation of translation(GO:0097167)
0.6 5.5 GO:0032264 IMP salvage(GO:0032264)
0.6 1.8 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.6 13.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.5 1.6 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069)
0.5 2.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.5 1.1 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.5 1.6 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.5 4.7 GO:0030916 otic vesicle formation(GO:0030916)
0.5 8.5 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.4 1.3 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.4 1.3 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.4 1.7 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.4 1.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.4 10.2 GO:0014823 response to activity(GO:0014823)
0.4 1.8 GO:0009597 detection of virus(GO:0009597)
0.3 2.7 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.3 1.0 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 0.9 GO:0021570 rhombomere 4 development(GO:0021570)
0.3 1.5 GO:0015886 heme transport(GO:0015886)
0.3 1.2 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.3 3.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.3 1.6 GO:0072675 osteoclast fusion(GO:0072675)
0.3 1.6 GO:0072318 clathrin coat disassembly(GO:0072318)
0.3 1.6 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.2 0.7 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.2 0.9 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.2 5.6 GO:0003417 growth plate cartilage development(GO:0003417)
0.2 3.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.2 1.5 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.2 0.9 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 0.8 GO:1902943 regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943) positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)
0.2 2.0 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 0.6 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.2 0.2 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.2 0.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 3.2 GO:0019374 galactolipid metabolic process(GO:0019374)
0.2 1.1 GO:0060005 vestibular reflex(GO:0060005)
0.2 5.4 GO:0006270 DNA replication initiation(GO:0006270)
0.2 1.7 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.2 1.0 GO:2000546 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.2 1.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.1 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.6 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.1 1.4 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.9 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.1 0.4 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.4 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.1 0.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 1.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.1 0.6 GO:0097048 dendritic cell apoptotic process(GO:0097048) neutrophil clearance(GO:0097350) regulation of dendritic cell apoptotic process(GO:2000668)
0.1 1.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.8 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.1 0.5 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616)
0.1 2.8 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.2 GO:0003032 detection of oxygen(GO:0003032)
0.1 4.9 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.1 0.3 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.1 1.4 GO:0048935 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.7 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 1.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.1 2.7 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 0.4 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 1.6 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.1 0.7 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 1.2 GO:0032060 bleb assembly(GO:0032060)
0.1 3.2 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 0.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.3 GO:0048752 semicircular canal morphogenesis(GO:0048752)
0.1 0.2 GO:1903242 regulation of cardiac muscle hypertrophy in response to stress(GO:1903242) positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 1.0 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.5 GO:0061470 interleukin-21 production(GO:0032625) T follicular helper cell differentiation(GO:0061470) interleukin-21 secretion(GO:0072619)
0.1 1.2 GO:0060009 negative regulation of adenylate cyclase activity(GO:0007194) Sertoli cell development(GO:0060009)
0.1 0.5 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.1 0.4 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 1.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 3.7 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 1.0 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 1.7 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 1.3 GO:1903963 arachidonic acid secretion(GO:0050482) arachidonate transport(GO:1903963)
0.0 0.7 GO:0007202 activation of phospholipase C activity(GO:0007202) positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.8 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.5 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.4 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.5 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 1.1 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.8 GO:0002347 response to tumor cell(GO:0002347)
0.0 0.4 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 1.2 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.8 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 1.0 GO:0001953 negative regulation of cell-matrix adhesion(GO:0001953)
0.0 0.3 GO:0048539 bone marrow development(GO:0048539)
0.0 0.3 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.6 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.8 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.8 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.6 GO:0002504 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 1.1 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.0 1.2 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 1.5 GO:0006611 protein export from nucleus(GO:0006611)
0.0 1.2 GO:0045576 mast cell activation(GO:0045576)
0.0 0.2 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0008355 olfactory learning(GO:0008355)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.1 GO:0043144 snoRNA processing(GO:0043144)
0.0 0.8 GO:0019835 cytolysis(GO:0019835)
0.0 0.3 GO:0008210 luteinization(GO:0001553) estrogen metabolic process(GO:0008210)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 5.4 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
1.7 8.5 GO:0097149 centralspindlin complex(GO:0097149)
1.2 17.8 GO:0042555 MCM complex(GO:0042555)
1.0 4.1 GO:1902737 viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
0.8 2.5 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.7 2.1 GO:0005588 collagen type V trimer(GO:0005588)
0.4 3.2 GO:0097427 microtubule bundle(GO:0097427)
0.3 1.2 GO:0044307 dendritic branch(GO:0044307)
0.3 2.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 13.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 1.5 GO:0000798 nuclear cohesin complex(GO:0000798)
0.2 3.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.2 1.3 GO:0001940 male pronucleus(GO:0001940)
0.2 0.6 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.1 1.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.8 GO:0061689 tricellular tight junction(GO:0061689)
0.1 1.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.4 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 4.1 GO:0031430 M band(GO:0031430)
0.1 1.0 GO:0031209 SCAR complex(GO:0031209)
0.1 0.5 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.7 GO:0000812 Swr1 complex(GO:0000812)
0.1 0.5 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.1 3.2 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 6.3 GO:0014704 intercalated disc(GO:0014704)
0.1 1.4 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.6 GO:0030673 axolemma(GO:0030673)
0.0 2.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.8 GO:0044291 cell-cell contact zone(GO:0044291)
0.0 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 2.1 GO:0031519 PcG protein complex(GO:0031519)
0.0 3.4 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 4.9 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 4.1 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 1.0 GO:0005876 spindle microtubule(GO:0005876)
0.0 2.0 GO:0005643 nuclear pore(GO:0005643)
0.0 0.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 6.0 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 3.3 GO:0043292 contractile fiber(GO:0043292)
0.0 1.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.8 GO:0005758 mitochondrial intermembrane space(GO:0005758)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.8 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
1.1 3.4 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.9 6.1 GO:0005499 vitamin D binding(GO:0005499)
0.7 5.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.6 5.5 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.6 1.8 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.6 4.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.6 2.8 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.5 3.8 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.5 2.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.4 17.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.4 1.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.4 1.5 GO:0015232 heme transporter activity(GO:0015232)
0.3 1.7 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.3 1.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 6.1 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.3 1.2 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.3 4.2 GO:0031432 titin binding(GO:0031432)
0.3 13.4 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.3 1.8 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 4.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.2 3.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 3.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 4.1 GO:0005523 tropomyosin binding(GO:0005523)
0.2 2.0 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.2 5.4 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 0.5 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.2 0.8 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.2 1.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.3 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 2.7 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 1.8 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.4 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.1 0.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 1.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.4 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 3.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 5.8 GO:0070888 E-box binding(GO:0070888)
0.1 1.0 GO:0071253 connexin binding(GO:0071253)
0.1 0.7 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.5 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 11.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.1 5.4 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.1 0.8 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 1.8 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 1.9 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 3.0 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 1.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.3 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 1.1 GO:0005537 mannose binding(GO:0005537)
0.0 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.7 GO:0017166 vinculin binding(GO:0017166)
0.0 0.5 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 1.1 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.7 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.4 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 1.4 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 3.0 GO:0005178 integrin binding(GO:0005178)
0.0 1.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 2.1 GO:0005179 hormone activity(GO:0005179)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 3.2 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 2.6 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.9 GO:0008026 ATP-dependent helicase activity(GO:0008026) purine NTP-dependent helicase activity(GO:0070035)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 6.6 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.4 5.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.4 17.4 PID ATR PATHWAY ATR signaling pathway
0.3 16.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.2 10.3 PID PLK1 PATHWAY PLK1 signaling events
0.1 3.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.1 1.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 2.9 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.7 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.0 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 2.1 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 6.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 2.1 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.0 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.1 PID NOTCH PATHWAY Notch signaling pathway
0.0 1.6 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 7.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.0 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 1.0 PID E2F PATHWAY E2F transcription factor network
0.0 0.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.0 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 17.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.3 5.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.3 5.2 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.3 13.2 REACTOME G1 PHASE Genes involved in G1 Phase
0.2 6.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.2 3.4 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 3.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 1.0 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.1 10.0 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.1 1.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 2.7 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 2.8 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 4.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.1 0.9 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.1 1.8 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.1 0.8 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 1.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 1.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 3.2 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 1.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 4.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 4.4 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.4 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.2 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 1.4 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 1.5 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.0 0.5 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 4.4 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.1 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING Genes involved in p75 NTR receptor-mediated signalling
0.0 0.4 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction