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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Erg

Z-value: 4.53

Motif logo

Transcription factors associated with Erg

Gene Symbol Gene ID Gene Info
ENSMUSG00000040732.12 ETS transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ergmm10_v2_chr16_-_95459245_954593840.849.5e-11Click!

Activity profile of Erg motif

Sorted Z-values of Erg motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_87793470 37.57 ENSMUST00000020779.4
myeloperoxidase
chr11_+_87793722 35.32 ENSMUST00000143021.2
myeloperoxidase
chr1_+_40515362 23.04 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chr3_-_90695706 20.51 ENSMUST00000069960.5
ENSMUST00000117167.1
S100 calcium binding protein A9 (calgranulin B)
chr14_-_43819639 19.11 ENSMUST00000100691.3
eosinophil-associated, ribonuclease A family, member 1
chr14_+_51853699 18.33 ENSMUST00000169070.1
ENSMUST00000074477.6
eosinophil-associated, ribonuclease A family, member 6
chr10_-_75940633 17.66 ENSMUST00000059658.4
predicted gene 867
chr14_-_43875517 17.18 ENSMUST00000179200.1
eosinophil-associated, ribonuclease A family, member 1
chr17_+_48359891 16.26 ENSMUST00000024792.6
triggering receptor expressed on myeloid cells-like 1
chr11_-_72550255 15.23 ENSMUST00000021154.6
spinster homolog 3
chr8_-_85380964 14.18 ENSMUST00000122452.1
myosin light chain kinase 3
chr10_-_81500132 13.43 ENSMUST00000053646.5
sphingosine-1-phosphate receptor 4
chr14_-_33185489 13.06 ENSMUST00000159606.1
WD repeat and FYVE domain containing 4
chr7_-_126369543 12.69 ENSMUST00000032997.6
linker for activation of T cells
chr4_-_118620763 11.92 ENSMUST00000071972.4
WD repeat domain 65
chr8_+_22974844 11.47 ENSMUST00000110688.2
ENSMUST00000121802.2
ankyrin 1, erythroid
chr7_-_127137807 11.42 ENSMUST00000049931.5
sialophorin
chr13_-_37050237 11.38 ENSMUST00000164727.1
coagulation factor XIII, A1 subunit
chr16_+_17980565 11.32 ENSMUST00000075371.3
pre-B lymphocyte gene 2
chr3_-_20242173 11.13 ENSMUST00000001921.1
carboxypeptidase A3, mast cell
chr2_+_118598209 10.67 ENSMUST00000038341.7
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
chr2_-_156839790 10.58 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
predicted gene 14230
chr8_-_71723308 9.86 ENSMUST00000125092.1
FCH domain only 1
chr6_+_87778084 9.34 ENSMUST00000032133.3
glycoprotein 9 (platelet)
chr9_-_123968683 9.27 ENSMUST00000026911.4
chemokine (C-C motif) receptor 1
chr3_+_84666192 8.80 ENSMUST00000107682.1
transmembrane protein 154
chrX_-_106840572 8.73 ENSMUST00000062010.9
zinc finger, CCHC domain containing 5
chr1_+_170277376 8.61 ENSMUST00000179976.1
SH2 domain protein 1B1
chr11_+_115887601 8.59 ENSMUST00000167507.2
myosin XVB
chr14_-_33185066 8.48 ENSMUST00000061753.8
ENSMUST00000130509.2
WD repeat and FYVE domain containing 4
chr6_+_60944472 8.27 ENSMUST00000129603.1
multimerin 1
chr16_+_33794345 8.18 ENSMUST00000023520.6
mucin 13, epithelial transmembrane
chr16_+_33794008 8.14 ENSMUST00000115044.1
mucin 13, epithelial transmembrane
chr10_-_6980376 8.14 ENSMUST00000105617.1
interaction protein for cytohesin exchange factors 1
chr2_+_164948219 8.12 ENSMUST00000017881.2
matrix metallopeptidase 9
chr17_+_32403006 8.07 ENSMUST00000065921.5
RIKEN cDNA A530088E08 gene
chr3_+_103832562 8.02 ENSMUST00000062945.5
BCLl2-like 15
chr16_-_19983005 7.94 ENSMUST00000058839.8
kelch-like 6
chr15_-_96642883 7.89 ENSMUST00000088452.4
solute carrier family 38, member 1
chr7_+_24897381 7.88 ENSMUST00000003469.7
CD79A antigen (immunoglobulin-associated alpha)
chr13_-_110357136 7.81 ENSMUST00000058806.5
Grb2-binding adaptor, transmembrane
chr17_-_14694223 7.67 ENSMUST00000170872.1
thrombospondin 2
chr9_+_56089962 7.57 ENSMUST00000059206.7
proline-serine-threonine phosphatase-interacting protein 1
chr3_+_68869563 7.56 ENSMUST00000054551.2
RIKEN cDNA 1110032F04 gene
chr2_-_32083783 7.40 ENSMUST00000056406.6
family with sequence similarity 78, member A
chr5_-_123879992 7.40 ENSMUST00000164267.1
G protein-coupled receptor 81
chr5_+_65863563 7.32 ENSMUST00000031106.4
ras homolog gene family, member H
chr2_+_103970115 7.31 ENSMUST00000111143.1
ENSMUST00000138815.1
LIM domain only 2
chrX_+_159303266 7.23 ENSMUST00000112491.1
ribosomal protein S6 kinase polypeptide 3
chr1_+_135133272 7.22 ENSMUST00000167080.1
protein tyrosine phosphatase, non-receptor type 7
chr6_-_123289862 7.18 ENSMUST00000032239.4
ENSMUST00000177367.1
C-type lectin domain family 4, member e
chr1_-_132367879 7.18 ENSMUST00000142609.1
transmembrane and coiled-coil domains 2
chr1_-_193201435 7.14 ENSMUST00000043550.4
TRAF3 interacting protein 3
chr1_+_135132693 6.89 ENSMUST00000049449.4
protein tyrosine phosphatase, non-receptor type 7
chr17_-_32403551 6.84 ENSMUST00000135618.1
ENSMUST00000063824.7
RAS protein activator like 3
chr19_-_11266122 6.64 ENSMUST00000169159.1
membrane-spanning 4-domains, subfamily A, member 1
chr11_+_70639118 6.48 ENSMUST00000055184.6
ENSMUST00000108551.2
glycoprotein 1b, alpha polypeptide
chr5_+_99979061 6.47 ENSMUST00000046721.1
RIKEN cDNA 4930524J08 gene
chr17_-_32403526 6.47 ENSMUST00000137458.1
RAS protein activator like 3
chr17_+_33638056 6.46 ENSMUST00000052079.7
PML-RAR alpha-regulated adaptor molecule 1
chr10_-_30655859 6.34 ENSMUST00000092610.4
nuclear receptor coactivator 7
chr2_+_103970221 6.33 ENSMUST00000111140.2
ENSMUST00000111139.2
LIM domain only 2
chr12_-_32208470 6.21 ENSMUST00000085469.5
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chrX_-_8090442 6.13 ENSMUST00000033505.6
Wiskott-Aldrich syndrome homolog (human)
chr13_+_55369732 6.09 ENSMUST00000063771.7
regulator of G-protein signaling 14
chrX_+_48146436 6.08 ENSMUST00000033427.6
SAM and SH3 domain containing 3
chr5_-_148392810 6.07 ENSMUST00000138257.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr4_-_63403330 6.04 ENSMUST00000035724.4
AT-hook transcription factor
chr7_-_25615874 6.03 ENSMUST00000098663.1
predicted gene 7092
chr13_-_19619820 5.99 ENSMUST00000002885.6
ependymin related protein 1 (zebrafish)
chr15_+_57985873 5.96 ENSMUST00000050374.2
family with sequence similarity 83, member A
chr1_+_171388954 5.96 ENSMUST00000056449.8
Rho GTPase activating protein 30
chr3_-_137981523 5.96 ENSMUST00000136613.1
ENSMUST00000029806.6
dual adaptor for phosphotyrosine and 3-phosphoinositides 1
chr17_+_28207778 5.88 ENSMUST00000002327.5
differentially expressed in FDCP 6
chr2_-_73486456 5.86 ENSMUST00000141264.1
WAS/WASL interacting protein family, member 1
chr4_+_126556935 5.82 ENSMUST00000048391.8
claspin
chr11_+_87755567 5.80 ENSMUST00000123700.1
RIKEN cDNA A430104N18 gene
chr12_+_110279228 5.74 ENSMUST00000097228.4
deiodinase, iodothyronine type III
chr11_+_104550663 5.71 ENSMUST00000018800.2
myosin, light polypeptide 4
chr1_-_170927567 5.68 ENSMUST00000046322.7
ENSMUST00000159171.1
Fc receptor-like A
chr4_+_126556994 5.62 ENSMUST00000147675.1
claspin
chrX_-_9469288 5.60 ENSMUST00000015484.3
cytochrome b-245, beta polypeptide
chr2_+_156840077 5.58 ENSMUST00000081335.6
ENSMUST00000073352.3
TGFB-induced factor homeobox 2
chr12_-_32208609 5.57 ENSMUST00000053215.7
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr8_-_68121527 5.53 ENSMUST00000178529.1
predicted gene, 21807
chr1_+_171767123 5.47 ENSMUST00000015460.4
signaling lymphocytic activation molecule family member 1
chr1_-_170927540 5.46 ENSMUST00000162136.1
ENSMUST00000162887.1
Fc receptor-like A
chr7_-_127218390 5.46 ENSMUST00000142356.1
ENSMUST00000106314.1
septin 1
chr2_-_26021679 5.42 ENSMUST00000036509.7
ubiquitin associated domain containing 1
chr3_+_124321031 5.40 ENSMUST00000058994.4
translocation associated membrane protein 1-like 1
chrX_-_164258186 5.34 ENSMUST00000112265.2
BMX non-receptor tyrosine kinase
chr6_+_125071277 5.31 ENSMUST00000140346.2
ENSMUST00000171989.1
lysophosphatidic acid receptor 5
chr2_-_26021532 5.31 ENSMUST00000136750.1
ubiquitin associated domain containing 1
chr6_-_129917650 5.24 ENSMUST00000118060.1
killer cell lectin-like receptor, subfamily A, member 5
chr8_-_88636117 5.23 ENSMUST00000034087.7
sorting nexin 20
chr1_-_133690100 5.20 ENSMUST00000169295.1
lymphocyte transmembrane adaptor 1
chr16_+_44765732 5.18 ENSMUST00000057488.8
CD200 receptor 1
chr14_+_44102654 5.14 ENSMUST00000074839.6
eosinophil-associated, ribonuclease A family, member 2
chr12_-_78906929 5.10 ENSMUST00000021544.7
pleckstrin 2
chr3_+_88616133 5.09 ENSMUST00000176500.1
ENSMUST00000177498.1
rho/rac guanine nucleotide exchange factor (GEF) 2
chrX_+_93675088 5.07 ENSMUST00000045898.3
phosphate cytidylyltransferase 1, choline, beta isoform
chr9_-_66919646 5.07 ENSMUST00000041139.7
RAB8B, member RAS oncogene family
chr4_-_129573637 5.01 ENSMUST00000102596.1
lymphocyte protein tyrosine kinase
chr7_+_29983948 5.00 ENSMUST00000148442.1
zinc finger protein 568
chr8_+_88289028 4.97 ENSMUST00000171456.1
adenylate cyclase 7
chr7_-_127218303 4.91 ENSMUST00000106313.1
septin 1
chr3_+_28781305 4.88 ENSMUST00000060500.7
eukaryotic translation initiation factor 5A2
chr9_+_122923050 4.87 ENSMUST00000051667.7
ENSMUST00000148851.1
zinc finger protein 105
chr11_-_101785252 4.82 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
ets variant gene 4 (E1A enhancer binding protein, E1AF)
chr3_-_14778452 4.78 ENSMUST00000094365.4
carbonic anhydrase 1
chr3_-_52104891 4.77 ENSMUST00000121440.1
mastermind like 3 (Drosophila)
chr2_+_84840612 4.73 ENSMUST00000111625.1
solute carrier family 43, member 1
chr5_-_137072254 4.65 ENSMUST00000077523.3
ENSMUST00000041388.4
serine (or cysteine) peptidase inhibitor, clade E, member 1
chr9_-_120068263 4.65 ENSMUST00000064165.3
ENSMUST00000177637.1
chemokine (C-X3-C) receptor 1
chr4_-_129558387 4.60 ENSMUST00000067240.4
lymphocyte protein tyrosine kinase
chr7_+_140218258 4.60 ENSMUST00000084460.6
CD163 molecule-like 1
chr6_+_65778988 4.59 ENSMUST00000031976.7
ENSMUST00000081219.7
ENSMUST00000031973.6
ENSMUST00000172638.1
PR domain containing 5
chr10_+_127323700 4.58 ENSMUST00000069548.5
Rho GTPase activating protein 9
chr11_-_102819663 4.55 ENSMUST00000092567.4
gap junction protein, gamma 1
chr9_-_20952838 4.53 ENSMUST00000004202.9
DNA methyltransferase (cytosine-5) 1
chr12_-_109600328 4.53 ENSMUST00000149046.2
retrotransposon-like 1
chr11_-_103363431 4.52 ENSMUST00000092557.5
Rho GTPase activating protein 27
chr6_-_16898441 4.50 ENSMUST00000031533.7
transcription factor EC
chr4_-_129558355 4.45 ENSMUST00000167288.1
ENSMUST00000134336.1
lymphocyte protein tyrosine kinase
chr2_+_163602331 4.44 ENSMUST00000152135.1
tocopherol (alpha) transfer protein-like
chr11_-_102469839 4.41 ENSMUST00000103086.3
integrin alpha 2b
chr1_+_152807877 4.39 ENSMUST00000027754.6
neutrophil cytosolic factor 2
chr9_+_21526144 4.35 ENSMUST00000086361.5
ENSMUST00000179459.1
ENSMUST00000173769.2
cDNA sequence AB124611
chr17_+_47594629 4.33 ENSMUST00000182846.1
cyclin D3
chr2_-_118728345 4.31 ENSMUST00000159756.1
phospholipase C, beta 2
chr14_+_70774304 4.28 ENSMUST00000022698.7
docking protein 2
chr16_-_21995478 4.26 ENSMUST00000074230.4
ENSMUST00000060673.6
lipase, member H
chr2_-_73453918 4.25 ENSMUST00000102679.1
WAS/WASL interacting protein family, member 1
chr2_-_164356507 4.24 ENSMUST00000109367.3
secretory leukocyte peptidase inhibitor
chr16_-_75909272 4.24 ENSMUST00000114239.2
SAM domain, SH3 domain and nuclear localization signals, 1
chr2_+_164805082 4.20 ENSMUST00000052107.4
zinc finger SWIM-type containing 3
chr6_+_134981998 4.14 ENSMUST00000167323.1
apolipoprotein L domain containing 1
chr10_+_79988584 4.10 ENSMUST00000004784.4
ENSMUST00000105374.1
calponin 2
chr4_-_43558386 4.07 ENSMUST00000130353.1
talin 1
chr15_-_9529868 4.06 ENSMUST00000003981.4
interleukin 7 receptor
chr1_+_75507077 4.04 ENSMUST00000037330.4
inhibin alpha
chr9_+_124102110 4.01 ENSMUST00000168841.1
ENSMUST00000055918.6
chemokine (C-C motif) receptor 2
chrX_-_136085206 3.98 ENSMUST00000138878.1
ENSMUST00000080929.6
nuclear RNA export factor 3
chr1_+_52630692 3.97 ENSMUST00000165859.1
transmembrane protein 194B
chr2_+_91650116 3.96 ENSMUST00000111331.2
Rho GTPase activating protein 1
chr14_+_52863299 3.96 ENSMUST00000103616.3
T cell receptor alpha variable 15D-1-DV6D-1
chr16_-_3718105 3.95 ENSMUST00000023180.7
ENSMUST00000100222.2
Mediterranean fever
chr8_+_69808672 3.95 ENSMUST00000036074.8
ENSMUST00000123453.1
Gem-interacting protein
chr17_+_47505043 3.93 ENSMUST00000182129.1
ENSMUST00000171031.1
cyclin D3
chr4_-_47010781 3.93 ENSMUST00000135777.1
predicted gene 568
chrX_+_134686519 3.89 ENSMUST00000124226.2
armadillo repeat containing, X-linked 4
chr17_+_47505149 3.87 ENSMUST00000183177.1
ENSMUST00000182848.1
cyclin D3
chr11_+_32533290 3.85 ENSMUST00000102821.3
serine/threonine kinase 10
chr17_+_47505211 3.83 ENSMUST00000182935.1
ENSMUST00000182506.1
cyclin D3
chr11_-_76509419 3.82 ENSMUST00000094012.4
active BCR-related gene
chr17_+_47505117 3.79 ENSMUST00000183044.1
ENSMUST00000037333.10
cyclin D3
chrX_+_159627534 3.77 ENSMUST00000073094.3
SH3-domain kinase binding protein 1
chr1_-_156474249 3.76 ENSMUST00000051396.6
sterol O-acyltransferase 1
chr9_+_124101944 3.76 ENSMUST00000171719.1
chemokine (C-C motif) receptor 2
chr4_+_135152496 3.71 ENSMUST00000119564.1
runt related transcription factor 3
chr11_+_61485431 3.70 ENSMUST00000064783.3
ENSMUST00000040522.6
microfibrillar-associated protein 4
chr16_-_36642742 3.70 ENSMUST00000135280.1
CD86 antigen
chr17_-_51826562 3.64 ENSMUST00000024720.4
ENSMUST00000129667.1
ENSMUST00000156051.1
ENSMUST00000169480.1
ENSMUST00000148559.1
special AT-rich sequence binding protein 1
chr7_-_126463100 3.63 ENSMUST00000032974.6
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr2_-_101883010 3.61 ENSMUST00000154525.1
proline rich 5 like
chr19_-_4191035 3.59 ENSMUST00000045864.2
TBC1 domain family, member 10c
chr2_+_129592818 3.59 ENSMUST00000153491.1
ENSMUST00000161620.1
ENSMUST00000179001.1
signal-regulatory protein alpha
chr2_+_165055668 3.58 ENSMUST00000081310.4
ENSMUST00000140951.1
CD40 antigen
chr7_+_75701965 3.58 ENSMUST00000094307.3
A kinase (PRKA) anchor protein 13
chr7_+_131032061 3.52 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr14_+_51129055 3.51 ENSMUST00000095923.3
ribonuclease, RNase A family, 6
chr3_+_98382438 3.48 ENSMUST00000056096.8
zinc finger protein 697
chr3_-_105932664 3.48 ENSMUST00000098758.2
RIKEN cDNA I830077J02 gene
chr1_-_54926311 3.47 ENSMUST00000179030.1
ENSMUST00000044359.9
ankyrin repeat domain 44
chr4_+_126024506 3.45 ENSMUST00000106162.1
colony stimulating factor 3 receptor (granulocyte)
chr5_+_34989473 3.43 ENSMUST00000114284.1
ENSMUST00000114285.1
regulator of G-protein signaling 12
chrX_+_164373363 3.43 ENSMUST00000033751.7
c-fos induced growth factor
chr11_-_79530569 3.40 ENSMUST00000103236.3
ENSMUST00000170799.1
ENSMUST00000170422.2
ecotropic viral integration site 2a
ecotropic viral integration site 2b
chr2_+_91650169 3.34 ENSMUST00000090614.4
Rho GTPase activating protein 1
chr7_+_43437073 3.31 ENSMUST00000070518.2
natural killer cell group 7 sequence
chr19_+_27217011 3.28 ENSMUST00000164746.1
ENSMUST00000172302.1
very low density lipoprotein receptor
chr2_-_148443543 3.27 ENSMUST00000099269.3
CD93 antigen
chr7_+_92819892 3.27 ENSMUST00000107180.1
ENSMUST00000107179.1
RAB30, member RAS oncogene family
chr2_-_101797650 3.25 ENSMUST00000141814.1
ENSMUST00000171088.1
ENSMUST00000043845.7
proline rich 5 like
chr10_-_62508097 3.25 ENSMUST00000159020.1
serglycin
chr2_-_118728430 3.23 ENSMUST00000102524.1
phospholipase C, beta 2
chr8_+_70501116 3.21 ENSMUST00000127983.1
cytokine receptor-like factor 1
chr9_-_60687459 3.21 ENSMUST00000114032.1
ENSMUST00000166168.1
ENSMUST00000132366.1
leucine rich repeat containing 49
chr4_-_83021102 3.20 ENSMUST00000071708.5
Fras1 related extracellular matrix protein 1
chr16_-_46120238 3.20 ENSMUST00000023336.9
CD96 antigen
chr2_-_93046053 3.18 ENSMUST00000111272.1
ENSMUST00000178666.1
ENSMUST00000147339.1
PR domain containing 11
chrX_+_159840463 3.18 ENSMUST00000112451.1
ENSMUST00000112453.2
SH3-domain kinase binding protein 1
chr17_+_47140942 3.16 ENSMUST00000077951.7
transcriptional regulating factor 1
chr5_-_122900267 3.15 ENSMUST00000031435.7
lysine (K)-specific demethylase 2B
chr3_+_88621274 3.15 ENSMUST00000107510.3
rho/rac guanine nucleotide exchange factor (GEF) 2
chr6_-_136941494 3.09 ENSMUST00000111892.1
Rho, GDP dissociation inhibitor (GDI) beta
chr3_+_88621102 3.09 ENSMUST00000029694.7
ENSMUST00000176804.1
rho/rac guanine nucleotide exchange factor (GEF) 2
chr15_-_64382908 3.08 ENSMUST00000177374.1
ENSMUST00000023008.9
ENSMUST00000110115.2
ENSMUST00000110114.3
ArfGAP with SH3 domain, ankyrin repeat and PH domain1
chr6_+_48904979 3.03 ENSMUST00000162948.1
ENSMUST00000167529.1
amine oxidase, copper-containing 1
chr11_+_101325063 3.02 ENSMUST00000041095.7
ENSMUST00000107264.1
amine oxidase, copper containing 2 (retina-specific)

Network of associatons between targets according to the STRING database.

First level regulatory network of Erg

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
24.3 72.9 GO:0002148 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
6.8 20.5 GO:0070488 neutrophil aggregation(GO:0070488)
3.8 11.4 GO:0002865 regulation of type IV hypersensitivity(GO:0001807) negative regulation of acute inflammatory response to antigenic stimulus(GO:0002865) negative regulation of hypersensitivity(GO:0002884)
3.6 10.7 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
2.7 8.1 GO:0071460 cellular response to cell-matrix adhesion(GO:0071460)
2.7 13.3 GO:0051140 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
2.6 10.4 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) meiotic metaphase plate congression(GO:0051311)
2.6 7.8 GO:2000451 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
2.6 2.6 GO:0032752 positive regulation of interleukin-3 production(GO:0032752) interleukin-3 biosynthetic process(GO:0042223) regulation of interleukin-3 biosynthetic process(GO:0045399) positive regulation of interleukin-3 biosynthetic process(GO:0045401) positive regulation of granulocyte macrophage colony-stimulating factor biosynthetic process(GO:0045425)
2.4 14.2 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
2.2 8.6 GO:0002765 immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
2.1 14.6 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
2.0 8.1 GO:0035744 T-helper 1 cell cytokine production(GO:0035744)
2.0 3.9 GO:0071608 macrophage inflammatory protein-1 alpha production(GO:0071608)
1.8 7.2 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
1.7 11.8 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
1.7 13.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
1.6 4.7 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
1.4 5.7 GO:0033370 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
1.4 5.6 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
1.3 7.9 GO:0006868 glutamine transport(GO:0006868)
1.3 8.9 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
1.2 3.7 GO:0002644 negative regulation of tolerance induction(GO:0002644)
1.2 7.3 GO:1903336 endosome localization(GO:0032439) negative regulation of vacuolar transport(GO:1903336)
1.2 3.6 GO:0051659 positive regulation of endoplasmic reticulum calcium ion concentration(GO:0032470) maintenance of mitochondrion location(GO:0051659) relaxation of skeletal muscle(GO:0090076)
1.2 14.1 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
1.2 5.8 GO:0034436 glycoprotein transport(GO:0034436)
1.1 11.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
1.1 4.6 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
1.1 4.5 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.1 15.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
1.0 10.3 GO:1902563 regulation of neutrophil degranulation(GO:0043313) regulation of neutrophil activation(GO:1902563)
1.0 6.1 GO:0002457 T cell antigen processing and presentation(GO:0002457)
1.0 5.0 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.9 21.7 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.9 13.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.9 4.4 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.9 11.4 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.8 3.4 GO:0010286 heat acclimation(GO:0010286)
0.8 11.0 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.8 6.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.8 4.9 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.8 4.0 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.8 3.2 GO:0002370 natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.8 4.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.8 12.7 GO:0006968 cellular defense response(GO:0006968)
0.8 6.9 GO:0038203 TORC2 signaling(GO:0038203)
0.8 5.3 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.8 2.3 GO:1901355 response to rapamycin(GO:1901355)
0.7 6.0 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.7 2.1 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.7 5.0 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.7 5.6 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.7 4.8 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.7 3.4 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.7 2.0 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685) negative regulation of interleukin-18 production(GO:0032701)
0.7 2.7 GO:0002283 neutrophil activation involved in immune response(GO:0002283)
0.6 1.9 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.6 5.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.6 3.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.6 1.8 GO:2000349 negative regulation of CD40 signaling pathway(GO:2000349)
0.6 3.6 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.6 2.3 GO:0032053 ciliary basal body organization(GO:0032053)
0.6 8.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.6 5.7 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.6 3.4 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.5 1.6 GO:2000043 endodermal cell fate determination(GO:0007493) stem cell fate specification(GO:0048866) regulation of cardiac cell fate specification(GO:2000043)
0.5 3.8 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.5 1.1 GO:0051892 negative regulation of cardioblast differentiation(GO:0051892)
0.5 6.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.5 1.6 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.5 2.6 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.5 1.0 GO:0060137 maternal process involved in parturition(GO:0060137)
0.5 4.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.5 2.0 GO:0031296 B cell costimulation(GO:0031296)
0.5 1.5 GO:0030538 embryonic genitalia morphogenesis(GO:0030538) embryonic hindgut morphogenesis(GO:0048619)
0.5 2.9 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.5 1.9 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.5 1.4 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.5 2.4 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.5 3.8 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.5 5.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.5 1.8 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.5 1.8 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.4 3.6 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.4 1.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.4 1.3 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.4 3.5 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.4 6.1 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.4 4.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.4 3.7 GO:0048251 elastic fiber assembly(GO:0048251) cellular response to UV-B(GO:0071493)
0.4 2.5 GO:0006543 glutamine catabolic process(GO:0006543)
0.4 1.6 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 1.2 GO:0072276 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.4 7.5 GO:0050913 sensory perception of bitter taste(GO:0050913)
0.4 1.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.4 1.5 GO:0032847 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) regulation of cellular pH reduction(GO:0032847)
0.4 1.1 GO:0021553 olfactory nerve development(GO:0021553)
0.4 1.1 GO:0006742 NADP catabolic process(GO:0006742)
0.4 6.5 GO:0042730 fibrinolysis(GO:0042730)
0.3 1.0 GO:0070543 response to linoleic acid(GO:0070543)
0.3 1.7 GO:0090273 regulation of somatostatin secretion(GO:0090273)
0.3 1.0 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.3 1.0 GO:0099548 trans-synaptic signaling by nitric oxide(GO:0099548)
0.3 4.7 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.3 1.3 GO:0032960 positive regulation of norepinephrine secretion(GO:0010701) regulation of inositol trisphosphate biosynthetic process(GO:0032960) positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.3 1.0 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.3 8.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.3 1.9 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.3 2.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.3 5.3 GO:0001865 NK T cell differentiation(GO:0001865)
0.3 0.9 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.3 0.9 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
0.3 3.0 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.3 10.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.3 1.5 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.3 0.6 GO:1903350 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.3 1.2 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.3 2.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.3 3.0 GO:0071280 cellular response to copper ion(GO:0071280)
0.3 0.8 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.3 2.9 GO:0070970 interleukin-2 secretion(GO:0070970)
0.3 5.6 GO:0038092 nodal signaling pathway(GO:0038092)
0.3 5.0 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.3 11.0 GO:0048821 erythrocyte development(GO:0048821)
0.3 5.4 GO:0002467 germinal center formation(GO:0002467)
0.3 1.0 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.3 1.5 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2 5.2 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 1.7 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 0.7 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.2 7.8 GO:0019731 antibacterial humoral response(GO:0019731)
0.2 1.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.2 10.6 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.2 1.8 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.2 5.6 GO:0043486 histone exchange(GO:0043486)
0.2 5.7 GO:0006910 phagocytosis, recognition(GO:0006910)
0.2 1.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2 6.4 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.2 4.1 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.2 5.7 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.2 0.8 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.2 2.9 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.2 0.4 GO:1990859 cellular response to endothelin(GO:1990859)
0.2 2.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.2 2.9 GO:0048194 Golgi vesicle budding(GO:0048194)
0.2 19.4 GO:0030168 platelet activation(GO:0030168)
0.2 3.6 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.2 3.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.2 2.6 GO:0015747 urate transport(GO:0015747)
0.2 2.9 GO:0015809 arginine transport(GO:0015809)
0.2 0.7 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.2 2.0 GO:0071360 cellular response to exogenous dsRNA(GO:0071360)
0.2 13.4 GO:0007596 blood coagulation(GO:0007596)
0.2 4.6 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.2 1.3 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.2 5.3 GO:0048266 behavioral response to pain(GO:0048266)
0.2 2.9 GO:0015693 magnesium ion transport(GO:0015693)
0.2 0.6 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.2 0.5 GO:0071639 positive regulation of monocyte chemotactic protein-1 production(GO:0071639)
0.2 1.8 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.2 1.8 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.1 2.0 GO:0001771 immunological synapse formation(GO:0001771)
0.1 1.5 GO:0010759 positive regulation of macrophage chemotaxis(GO:0010759)
0.1 1.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 2.6 GO:0001911 negative regulation of leukocyte mediated cytotoxicity(GO:0001911)
0.1 4.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 3.8 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.1 0.5 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.1 2.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 1.0 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 1.2 GO:0045759 negative regulation of action potential(GO:0045759)
0.1 7.3 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
0.1 7.9 GO:0042100 B cell proliferation(GO:0042100)
0.1 0.5 GO:0040010 positive regulation of growth rate(GO:0040010)
0.1 1.3 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.1 1.3 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 1.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.3 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.1 2.4 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.1 1.8 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.1 0.8 GO:0010669 epithelial structure maintenance(GO:0010669)
0.1 3.9 GO:0042982 amyloid precursor protein metabolic process(GO:0042982)
0.1 0.6 GO:0090383 phagosome acidification(GO:0090383)
0.1 1.9 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 4.3 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.5 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 7.5 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.1 0.7 GO:0016584 nucleosome positioning(GO:0016584)
0.1 1.1 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.1 1.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 2.2 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.1 1.6 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.1 2.9 GO:0006379 mRNA cleavage(GO:0006379)
0.1 1.1 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694)
0.1 0.7 GO:0071236 cellular response to antibiotic(GO:0071236)
0.1 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.1 0.8 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.1 0.9 GO:0031268 pseudopodium organization(GO:0031268)
0.1 1.2 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.1 0.5 GO:0007096 regulation of exit from mitosis(GO:0007096)
0.1 0.7 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.1 0.4 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 2.9 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.1 2.0 GO:0007099 centriole replication(GO:0007099)
0.1 2.4 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.7 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 3.2 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.1 0.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 0.2 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 2.5 GO:0051567 histone H3-K9 methylation(GO:0051567)
0.1 0.4 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 1.4 GO:0045761 regulation of adenylate cyclase activity(GO:0045761)
0.0 1.6 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.0 2.1 GO:0007091 metaphase/anaphase transition of mitotic cell cycle(GO:0007091)
0.0 1.5 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 1.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.7 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.4 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 2.4 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.0 0.2 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.2 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 2.4 GO:0031532 actin cytoskeleton reorganization(GO:0031532)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 2.1 GO:0042113 B cell activation(GO:0042113)
0.0 1.3 GO:0042632 cholesterol homeostasis(GO:0042632) sterol homeostasis(GO:0055092)
0.0 1.9 GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage(GO:0008630)
0.0 1.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 1.1 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.7 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.8 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.7 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 1.1 GO:0051028 mRNA transport(GO:0051028)
0.0 2.8 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.0 1.1 GO:0031497 chromatin assembly(GO:0031497)
0.0 1.3 GO:0008203 cholesterol metabolic process(GO:0008203)
0.0 0.8 GO:0031338 regulation of vesicle fusion(GO:0031338)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
4.3 69.0 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
2.9 11.8 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
1.9 5.6 GO:0005607 laminin-2 complex(GO:0005607)
1.5 7.5 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
1.3 4.0 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
1.3 4.0 GO:0042272 nuclear RNA export factor complex(GO:0042272)
1.1 7.7 GO:0019815 B cell receptor complex(GO:0019815)
1.0 3.8 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
1.0 11.4 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.9 7.6 GO:0005826 actomyosin contractile ring(GO:0005826)
0.9 4.7 GO:0042583 chromaffin granule(GO:0042583)
0.9 3.7 GO:0071953 elastic fiber(GO:0071953)
0.9 10.4 GO:0072687 meiotic spindle(GO:0072687)
0.8 10.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.8 3.2 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.7 13.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.7 2.2 GO:0030905 retromer, tubulation complex(GO:0030905)
0.7 2.9 GO:0008623 CHRAC(GO:0008623)
0.7 0.7 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.7 2.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.6 3.8 GO:0097443 sorting endosome(GO:0097443)
0.6 3.8 GO:0031673 H zone(GO:0031673)
0.6 7.3 GO:0005687 U4 snRNP(GO:0005687)
0.6 14.3 GO:0000242 pericentriolar material(GO:0000242)
0.5 5.7 GO:0042629 mast cell granule(GO:0042629)
0.5 3.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.5 11.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.5 1.5 GO:0005940 septin ring(GO:0005940)
0.4 6.9 GO:0031932 TORC2 complex(GO:0031932)
0.4 2.1 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.4 3.8 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.4 2.0 GO:0098536 deuterosome(GO:0098536)
0.4 1.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.4 3.6 GO:0001739 sex chromatin(GO:0001739)
0.4 1.4 GO:0045160 myosin I complex(GO:0045160)
0.4 21.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.3 2.7 GO:0042382 paraspeckles(GO:0042382)
0.3 14.7 GO:0002102 podosome(GO:0002102)
0.3 1.3 GO:0008537 proteasome activator complex(GO:0008537)
0.3 3.0 GO:0031080 nuclear pore outer ring(GO:0031080)
0.3 6.5 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.3 1.1 GO:1990696 USH2 complex(GO:1990696)
0.3 7.3 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.3 15.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.2 0.5 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.2 2.2 GO:0061574 ASAP complex(GO:0061574)
0.2 3.4 GO:0001891 phagocytic cup(GO:0001891)
0.2 5.7 GO:0043196 varicosity(GO:0043196)
0.2 6.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.2 10.7 GO:0008180 COP9 signalosome(GO:0008180)
0.2 1.6 GO:0097208 alveolar lamellar body(GO:0097208)
0.2 2.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.2 5.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 1.6 GO:0000801 central element(GO:0000801)
0.2 3.6 GO:0031527 filopodium membrane(GO:0031527)
0.2 2.9 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 6.2 GO:0030139 endocytic vesicle(GO:0030139)
0.1 5.0 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 8.9 GO:0005903 brush border(GO:0005903)
0.1 1.9 GO:0031011 Ino80 complex(GO:0031011)
0.1 3.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 1.0 GO:0090543 Flemming body(GO:0090543)
0.1 1.4 GO:0005686 U2 snRNP(GO:0005686)
0.1 11.0 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 1.5 GO:0046930 pore complex(GO:0046930)
0.1 1.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 4.7 GO:0032809 neuronal cell body membrane(GO:0032809)
0.1 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.1 3.3 GO:0005876 spindle microtubule(GO:0005876)
0.1 11.9 GO:0000922 spindle pole(GO:0000922)
0.1 5.2 GO:0031901 early endosome membrane(GO:0031901)
0.1 4.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 5.7 GO:0031672 A band(GO:0031672)
0.1 4.6 GO:0097517 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 3.4 GO:0097440 apical dendrite(GO:0097440)
0.1 3.6 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 3.1 GO:0031519 PcG protein complex(GO:0031519)
0.1 8.7 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.1 1.9 GO:0005922 connexon complex(GO:0005922)
0.1 1.4 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.7 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.1 1.4 GO:0016460 myosin II complex(GO:0016460)
0.1 3.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.1 5.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.1 11.6 GO:0001726 ruffle(GO:0001726)
0.1 4.3 GO:0005643 nuclear pore(GO:0005643)
0.1 4.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.9 GO:0036038 MKS complex(GO:0036038)
0.1 1.8 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 5.2 GO:0072562 blood microparticle(GO:0072562)
0.0 17.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 5.7 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 1.5 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.4 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.6 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 1.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 5.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 4.3 GO:0005884 actin filament(GO:0005884)
0.0 1.2 GO:0001772 immunological synapse(GO:0001772)
0.0 0.8 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 2.0 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 2.3 GO:0005814 centriole(GO:0005814)
0.0 2.0 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 4.3 GO:0001650 fibrillar center(GO:0001650)
0.0 1.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 2.6 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0035371 microtubule plus-end(GO:0035371)
0.0 5.1 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 4.7 GO:0000323 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 4.6 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 0.5 GO:0014704 intercalated disc(GO:0014704)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 3.3 GO:0016324 apical plasma membrane(GO:0016324)
0.0 1.2 GO:0005923 bicellular tight junction(GO:0005923)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 17.0 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
3.8 15.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
2.9 22.9 GO:0050786 RAGE receptor binding(GO:0050786)
2.8 14.1 GO:0042610 CD8 receptor binding(GO:0042610)
2.1 23.0 GO:0004908 interleukin-1 receptor activity(GO:0004908)
2.0 14.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
1.9 5.8 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
1.9 5.7 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
1.9 11.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.6 7.9 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
1.4 11.5 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
1.2 6.1 GO:0030621 U4 snRNA binding(GO:0030621)
1.2 72.9 GO:0004601 peroxidase activity(GO:0004601)
1.1 11.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
1.1 4.6 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
1.1 11.8 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
1.0 3.0 GO:0052593 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
1.0 12.8 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
1.0 3.8 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.9 4.6 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.9 4.4 GO:0070051 fibrinogen binding(GO:0070051)
0.8 3.1 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.8 6.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.7 6.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.7 2.9 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.7 0.7 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.7 2.0 GO:0071208 histone pre-mRNA DCP binding(GO:0071208)
0.6 2.6 GO:0019767 IgE receptor activity(GO:0019767)
0.6 5.1 GO:0030911 TPR domain binding(GO:0030911)
0.6 7.4 GO:0030274 LIM domain binding(GO:0030274)
0.6 3.0 GO:0008131 primary amine oxidase activity(GO:0008131)
0.6 4.8 GO:0004064 arylesterase activity(GO:0004064)
0.6 9.9 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.6 4.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.6 2.2 GO:1990460 leptin receptor binding(GO:1990460)
0.5 4.7 GO:0043208 glycosphingolipid binding(GO:0043208)
0.5 4.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.5 60.4 GO:0004540 ribonuclease activity(GO:0004540)
0.4 4.0 GO:0034711 inhibin binding(GO:0034711)
0.4 21.7 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.4 3.3 GO:0001849 complement component C1q binding(GO:0001849)
0.4 2.5 GO:0004359 glutaminase activity(GO:0004359)
0.4 3.2 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.4 13.4 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.4 6.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.4 6.0 GO:0004016 adenylate cyclase activity(GO:0004016)
0.4 1.5 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.4 8.9 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.3 1.0 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.3 11.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 11.1 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.3 6.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.3 4.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.3 3.6 GO:0005338 nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.3 1.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.3 1.5 GO:0043515 kinetochore binding(GO:0043515)
0.3 6.0 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.3 5.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 15.1 GO:0035591 signaling adaptor activity(GO:0035591)
0.3 7.6 GO:0001968 fibronectin binding(GO:0001968)
0.3 1.0 GO:0001847 opsonin receptor activity(GO:0001847)
0.2 2.9 GO:0050700 CARD domain binding(GO:0050700)
0.2 14.6 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.2 1.8 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 2.9 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.2 5.2 GO:0042169 SH2 domain binding(GO:0042169)
0.2 1.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 6.9 GO:0043274 phospholipase binding(GO:0043274)
0.2 1.3 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2 7.0 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.2 4.9 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 8.4 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.2 2.4 GO:0051525 NFAT protein binding(GO:0051525)
0.2 2.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.2 1.5 GO:0051434 BH3 domain binding(GO:0051434)
0.2 1.7 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.2 0.7 GO:0019770 IgG receptor activity(GO:0019770)
0.2 33.7 GO:0017124 SH3 domain binding(GO:0017124)
0.2 7.0 GO:0030544 Hsp70 protein binding(GO:0030544)
0.2 2.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.2 0.5 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.2 3.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.2 1.3 GO:0016531 copper chaperone activity(GO:0016531) cuprous ion binding(GO:1903136)
0.2 3.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.2 0.5 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.9 GO:0004111 creatine kinase activity(GO:0004111)
0.1 1.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 1.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 4.0 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.1 1.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 4.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 1.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 1.1 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.1 4.2 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 5.7 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.1 4.1 GO:0003785 actin monomer binding(GO:0003785)
0.1 0.4 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 3.2 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.9 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 1.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.8 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 3.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 1.8 GO:0035173 histone kinase activity(GO:0035173)
0.1 3.4 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 4.3 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.8 GO:0004697 protein kinase C activity(GO:0004697)
0.1 2.6 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.1 0.2 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1 0.7 GO:0051400 BH domain binding(GO:0051400)
0.1 2.9 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 1.3 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.1 8.8 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 1.9 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 1.0 GO:0045499 chemorepellent activity(GO:0045499)
0.1 4.3 GO:0009055 electron carrier activity(GO:0009055)
0.1 5.1 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 2.9 GO:0004620 phospholipase activity(GO:0004620)
0.1 4.0 GO:0005518 collagen binding(GO:0005518)
0.1 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 1.1 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 1.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.3 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.2 GO:0019961 interferon binding(GO:0019961)
0.0 2.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.2 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.7 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 9.1 GO:0044822 mRNA binding(GO:0003729) poly(A) RNA binding(GO:0044822)
0.0 1.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 15.2 GO:0005525 GTP binding(GO:0005525)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 1.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 4.2 GO:0019903 protein phosphatase binding(GO:0019903)
0.0 0.6 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 1.2 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.2 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.3 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0034431 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.1 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 2.2 GO:0046332 SMAD binding(GO:0046332)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 1.4 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.8 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.1 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.2 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.2 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.6 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 88.0 PID IL23 PATHWAY IL23-mediated signaling events
1.0 13.9 PID S1P S1P4 PATHWAY S1P4 pathway
1.0 11.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.8 14.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.8 13.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.7 27.8 PID EPHA FWDPATHWAY EPHA forward signaling
0.5 8.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.4 7.5 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.4 5.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.4 16.6 PID REELIN PATHWAY Reelin signaling pathway
0.4 19.3 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.4 8.0 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.4 13.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.4 8.1 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.4 12.8 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.4 10.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.4 22.1 PID PLK1 PATHWAY PLK1 signaling events
0.3 12.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.3 3.8 ST JAK STAT PATHWAY Jak-STAT Pathway
0.3 8.9 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.3 7.5 PID CD40 PATHWAY CD40/CD40L signaling
0.3 10.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.3 15.1 PID BCR 5PATHWAY BCR signaling pathway
0.3 10.9 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.3 2.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.2 9.0 PID AURORA B PATHWAY Aurora B signaling
0.2 3.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.2 10.6 PID RHOA REG PATHWAY Regulation of RhoA activity
0.2 6.9 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.2 6.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.2 4.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 25.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.1 2.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 4.1 PID RAC1 PATHWAY RAC1 signaling pathway
0.1 1.2 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.1 3.0 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 2.8 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.1 1.9 PID RHOA PATHWAY RhoA signaling pathway
0.1 0.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.1 5.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.1 1.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.1 1.9 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.1 4.7 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 13.8