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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Epas1_Bcl3

Z-value: 2.01

Motif logo

Transcription factors associated with Epas1_Bcl3

Gene Symbol Gene ID Gene Info
ENSMUSG00000024140.9 endothelial PAS domain protein 1
ENSMUSG00000053175.10 B cell leukemia/lymphoma 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Epas1mm10_v2_chr17_+_86753900_867539140.334.9e-02Click!
Bcl3mm10_v2_chr7_-_19822698_19822776-0.096.0e-01Click!

Activity profile of Epas1_Bcl3 motif

Sorted Z-values of Epas1_Bcl3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_28560704 13.10 ENSMUST00000114785.1
ENSMUST00000025062.3
colipase, pancreatic
chr14_-_60177482 12.25 ENSMUST00000140924.1
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr14_+_55765956 9.80 ENSMUST00000057569.3
leukotriene B4 receptor 1
chr8_+_79028587 8.84 ENSMUST00000119254.1
zinc finger protein 827
chr5_-_134747241 8.59 ENSMUST00000015138.9
elastin
chr10_+_127725392 7.94 ENSMUST00000026466.3
tachykinin 2
chr3_+_51661167 7.73 ENSMUST00000099106.3
microsomal glutathione S-transferase 2
chr8_+_79028317 6.21 ENSMUST00000087927.4
ENSMUST00000098614.2
zinc finger protein 827
chr3_-_132950043 5.77 ENSMUST00000117164.1
ENSMUST00000093971.4
ENSMUST00000042729.9
ENSMUST00000042744.9
ENSMUST00000117811.1
nephronectin
chr3_+_51661209 4.89 ENSMUST00000161590.1
microsomal glutathione S-transferase 2
chr19_+_47228804 4.38 ENSMUST00000111807.3
neuralized homolog 1A (Drosophila)
chr4_-_134018829 4.35 ENSMUST00000051674.2
lin-28 homolog A (C. elegans)
chr6_+_145145473 4.24 ENSMUST00000156849.1
ENSMUST00000132948.1
lymphoid-restricted membrane protein
chr1_+_75507077 4.21 ENSMUST00000037330.4
inhibin alpha
chr11_+_95010277 4.07 ENSMUST00000124735.1
sterile alpha motif domain containing 14
chr7_-_100863373 3.78 ENSMUST00000142885.1
ENSMUST00000008462.3
RELT tumor necrosis factor receptor
chr12_+_102554966 3.65 ENSMUST00000021610.5
chromogranin A
chr11_-_102365111 3.63 ENSMUST00000006749.9
solute carrier family 4 (anion exchanger), member 1
chr6_+_36388055 3.40 ENSMUST00000172278.1
cholinergic receptor, muscarinic 2, cardiac
chr4_+_17853451 3.31 ENSMUST00000029881.3
matrix metallopeptidase 16
chr4_+_49059256 3.06 ENSMUST00000076670.2
RIKEN cDNA E130309F12 gene
chr13_+_55369732 3.02 ENSMUST00000063771.7
regulator of G-protein signaling 14
chr14_-_54994541 3.00 ENSMUST00000153783.1
ENSMUST00000168485.1
ENSMUST00000102803.3
myosin, heavy polypeptide 7, cardiac muscle, beta
chr6_+_128399766 2.99 ENSMUST00000001561.5
nuclear receptor interacting protein 2
chr17_+_36869567 2.93 ENSMUST00000060524.9
tripartite motif-containing 10
chr14_-_70630149 2.84 ENSMUST00000022694.9
dematin actin binding protein
chr12_-_16800674 2.78 ENSMUST00000162112.1
gene regulated by estrogen in breast cancer protein
chr10_+_79879614 2.77 ENSMUST00000006679.8
proteinase 3
chr9_+_65101453 2.74 ENSMUST00000077696.6
ENSMUST00000035499.4
ENSMUST00000166273.1
immunoglobulin superfamily, DCC subclass, member 4
chr15_+_80173642 2.63 ENSMUST00000044970.6
mannoside acetylglucosaminyltransferase 3
chr15_+_81936911 2.54 ENSMUST00000135663.1
cold shock domain containing C2, RNA binding
chr2_+_105127200 2.51 ENSMUST00000139585.1
Wilms tumor 1 homolog
chr10_+_42860348 2.50 ENSMUST00000063063.7
sex comb on midleg-like 4 (Drosophila)
chr11_-_101785252 2.41 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
ets variant gene 4 (E1A enhancer binding protein, E1AF)
chr8_-_48555846 2.41 ENSMUST00000110345.1
ENSMUST00000110343.1
teneurin transmembrane protein 3
chr9_+_62858085 2.40 ENSMUST00000034777.6
ENSMUST00000163820.1
calmodulin-like 4
chr7_+_122671378 2.35 ENSMUST00000182563.1
calcium channel, voltage-dependent, gamma subunit 3
chr3_-_98339921 2.27 ENSMUST00000065793.5
3-phosphoglycerate dehydrogenase
chr10_+_17796256 2.24 ENSMUST00000037964.6
taxilin beta
chr7_+_79660196 2.19 ENSMUST00000035977.7
TOPBP1-interacting checkpoint and replication regulator
chr11_+_95009852 2.17 ENSMUST00000055947.3
sterile alpha motif domain containing 14
chr7_-_126369543 2.15 ENSMUST00000032997.6
linker for activation of T cells
chr17_-_35066170 2.15 ENSMUST00000174190.1
ENSMUST00000097337.1
expressed sequence AU023871
chr7_+_99535652 2.14 ENSMUST00000032995.8
ENSMUST00000162404.1
arrestin, beta 1
chr3_-_94473591 2.13 ENSMUST00000029785.3
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
chr2_+_4300462 2.12 ENSMUST00000175669.1
FERM domain containing 4A
chr3_-_127225847 2.09 ENSMUST00000182726.1
ENSMUST00000182779.1
ankyrin 2, brain
chr6_+_128399881 2.06 ENSMUST00000120405.1
nuclear receptor interacting protein 2
chr4_+_130913264 2.05 ENSMUST00000156225.1
ENSMUST00000156742.1
lysosomal-associated protein transmembrane 5
chr2_+_118814195 2.03 ENSMUST00000110842.1
kinetochore-localized astrin/SPAG5 binding
chr10_+_42860776 2.03 ENSMUST00000105494.1
sex comb on midleg-like 4 (Drosophila)
chr6_-_128826305 1.99 ENSMUST00000174544.1
ENSMUST00000172887.1
ENSMUST00000032472.4
killer cell lectin-like receptor subfamily B member 1B
chr9_+_110763646 1.99 ENSMUST00000079784.7
myosin, light polypeptide 3
chr12_-_14152038 1.95 ENSMUST00000020926.6
family with sequence similarity 84, member A
chr2_+_118814237 1.94 ENSMUST00000028803.7
ENSMUST00000126045.1
kinetochore-localized astrin/SPAG5 binding
chr11_+_69095217 1.91 ENSMUST00000101004.2
period circadian clock 1
chr9_+_78615501 1.89 ENSMUST00000093812.4
CD109 antigen
chr2_+_118813995 1.87 ENSMUST00000134661.1
kinetochore-localized astrin/SPAG5 binding
chr1_-_155232710 1.86 ENSMUST00000035914.3
cDNA sequence BC034090
chr7_+_110772604 1.81 ENSMUST00000005829.6
adenosine monophosphate deaminase 3
chr11_-_97996171 1.72 ENSMUST00000042971.9
ADP-ribosylation factor-like 5C
chr4_-_126325672 1.71 ENSMUST00000102616.1
tektin 2
chr9_-_40346290 1.71 ENSMUST00000121357.1
GRAM domain containing 1B
chr5_-_137072254 1.70 ENSMUST00000077523.3
ENSMUST00000041388.4
serine (or cysteine) peptidase inhibitor, clade E, member 1
chr14_-_70524068 1.66 ENSMUST00000022692.3
surfactant associated protein C
chr1_-_171607321 1.66 ENSMUST00000111277.1
ENSMUST00000004827.7
lymphocyte antigen 9
chr17_-_29237759 1.63 ENSMUST00000137727.1
ENSMUST00000024805.7
copine V
chr8_+_70152754 1.62 ENSMUST00000072500.6
ENSMUST00000164040.1
ENSMUST00000110146.2
ENSMUST00000110143.1
ENSMUST00000110141.2
ENSMUST00000110140.1
RIKEN cDNA 2310045N01 gene
myocyte enhancer factor 2B
chr11_-_70352029 1.62 ENSMUST00000019068.6
arachidonate 15-lipoxygenase
chr7_+_122671401 1.61 ENSMUST00000182095.1
calcium channel, voltage-dependent, gamma subunit 3
chr5_+_27261916 1.60 ENSMUST00000101471.3
dipeptidylpeptidase 6
chr7_+_110768169 1.57 ENSMUST00000170374.1
adenosine monophosphate deaminase 3
chr5_-_67847400 1.56 ENSMUST00000113652.1
ENSMUST00000113651.1
ENSMUST00000037380.8
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr9_+_36832684 1.55 ENSMUST00000034630.8
fasciculation and elongation protein zeta 1 (zygin I)
chr17_+_56304313 1.54 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
ubiquitin-like, containing PHD and RING finger domains, 1
chr18_+_49979427 1.52 ENSMUST00000148989.2
tumor necrosis factor, alpha-induced protein 8
chr14_-_76556662 1.51 ENSMUST00000064517.7
stress-associated endoplasmic reticulum protein family member 2
chr3_-_104818266 1.51 ENSMUST00000168015.1
Moloney leukemia virus 10
chr9_-_102354685 1.50 ENSMUST00000035129.7
ENSMUST00000085169.5
Eph receptor B1
chr17_-_78906899 1.50 ENSMUST00000042683.6
ENSMUST00000169544.1
sulfotransferase family, cytosolic, 6B, member 1
chr2_+_174760619 1.47 ENSMUST00000029030.2
endothelin 3
chr8_+_123332676 1.46 ENSMUST00000010298.6
spire homolog 2 (Drosophila)
chr10_+_42860648 1.45 ENSMUST00000105495.1
sex comb on midleg-like 4 (Drosophila)
chr2_+_135659625 1.43 ENSMUST00000134310.1
phospholipase C, beta 4
chr4_+_130913120 1.38 ENSMUST00000151698.1
lysosomal-associated protein transmembrane 5
chr19_+_16956110 1.37 ENSMUST00000087689.4
prune homolog 2 (Drosophila)
chr14_-_31577318 1.33 ENSMUST00000112027.2
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr7_-_141117772 1.31 ENSMUST00000067836.7
anoctamin 9
chr3_-_152668135 1.30 ENSMUST00000045262.6
adenylate kinase 5
chr11_-_70255329 1.30 ENSMUST00000108574.2
ENSMUST00000000329.2
arachidonate 12-lipoxygenase
chr3_+_105452326 1.29 ENSMUST00000098761.3
potassium voltage-gated channel, Shal-related family, member 3
chr17_-_12868126 1.28 ENSMUST00000089015.3
MAS1 oncogene
chr9_-_44234014 1.27 ENSMUST00000037644.6
Casitas B-lineage lymphoma
chr5_-_30461902 1.27 ENSMUST00000133509.1
ENSMUST00000074171.6
ENSMUST00000114747.2
ENSMUST00000144125.1
otoferlin
chr3_-_104818539 1.27 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
Moloney leukemia virus 10
chr14_+_116925516 1.26 ENSMUST00000125435.1
glypican 6
chr14_+_116925379 1.25 ENSMUST00000088483.3
glypican 6
chr14_+_84443553 1.25 ENSMUST00000071370.5
protocadherin 17
chr4_-_126325641 1.25 ENSMUST00000131113.1
tektin 2
chr3_-_123034943 1.23 ENSMUST00000029761.7
myozenin 2
chr6_-_29179584 1.22 ENSMUST00000159200.1
proline-rich transmembrane protein 4
chr1_-_171607378 1.22 ENSMUST00000068878.7
lymphocyte antigen 9
chr4_+_47091909 1.20 ENSMUST00000045041.5
ENSMUST00000107744.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12
chr2_+_143546144 1.20 ENSMUST00000028905.9
proprotein convertase subtilisin/kexin type 2
chr18_+_4634912 1.17 ENSMUST00000037029.5
RIKEN cDNA 9430020K01 gene
chr13_-_28953690 1.17 ENSMUST00000067230.5
SRY-box containing gene 4
chr2_+_106695594 1.17 ENSMUST00000016530.7
metallophosphoesterase domain containing 2
chr2_+_27886416 1.16 ENSMUST00000028280.7
collagen, type V, alpha 1
chr9_+_21368014 1.16 ENSMUST00000067646.4
ENSMUST00000115414.1
interleukin enhancer binding factor 3
chr18_+_49979514 1.15 ENSMUST00000179937.1
tumor necrosis factor, alpha-induced protein 8
chr1_-_192855723 1.13 ENSMUST00000155579.1
SERTA domain containing 4
chr10_-_12964252 1.13 ENSMUST00000163425.1
ENSMUST00000042861.5
syntaxin 11
chr18_+_21072329 1.11 ENSMUST00000082235.4
meprin 1 beta
chr7_+_99535439 1.11 ENSMUST00000098266.2
ENSMUST00000179755.1
arrestin, beta 1
chr2_+_105126505 1.10 ENSMUST00000143043.1
Wilms tumor 1 homolog
chr8_-_116732991 1.09 ENSMUST00000109102.2
chromodomain protein, Y chromosome-like 2
chr17_+_29093763 1.06 ENSMUST00000023829.6
cyclin-dependent kinase inhibitor 1A (P21)
chr8_+_68880491 1.06 ENSMUST00000015712.8
lipoprotein lipase
chr3_-_127225917 1.05 ENSMUST00000182064.1
ENSMUST00000182662.1
ankyrin 2, brain
chr15_-_56694525 1.04 ENSMUST00000050544.7
hyaluronan synthase 2
chr15_+_82275197 1.03 ENSMUST00000116423.1
septin 3
chr15_+_81936753 1.03 ENSMUST00000038757.7
cold shock domain containing C2, RNA binding
chr17_+_34608997 1.02 ENSMUST00000114140.3
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr3_+_134236483 1.02 ENSMUST00000181904.1
ENSMUST00000053048.9
CXXC finger 4
chr8_+_82863351 1.00 ENSMUST00000078525.5
ring finger protein 150
chr15_+_99670574 1.00 ENSMUST00000023758.7
acid-sensing (proton-gated) ion channel 1
chrX_-_102250940 0.99 ENSMUST00000134887.1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chrX_+_69360294 0.98 ENSMUST00000033532.6
AF4/FMR2 family, member 2
chr19_+_23758819 0.96 ENSMUST00000025830.7
amyloid beta (A4) precursor protein binding, family A, member 1
chr11_+_3983636 0.95 ENSMUST00000078757.1
galactose-3-O-sulfotransferase 1
chr3_-_116253467 0.94 ENSMUST00000090473.5
G-protein coupled receptor 88
chr19_-_41743665 0.94 ENSMUST00000025993.3
slit homolog 1 (Drosophila)
chrX_+_144688907 0.94 ENSMUST00000112843.1
zinc finger, CCHC domain containing 16
chr5_+_81021202 0.93 ENSMUST00000117253.1
ENSMUST00000120128.1
latrophilin 3
chr4_-_88033328 0.93 ENSMUST00000078090.5
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr2_+_153345809 0.93 ENSMUST00000109790.1
additional sex combs like 1
chr8_+_83997613 0.90 ENSMUST00000095228.3
sterile alpha motif domain containing 1
chr19_+_6400523 0.89 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
RAS, guanyl releasing protein 2
chr14_+_116925291 0.88 ENSMUST00000078849.4
glypican 6
chr11_+_34314757 0.88 ENSMUST00000165963.1
ENSMUST00000093192.3
family with sequence similarity 196, member B
chr16_-_44558879 0.88 ENSMUST00000114634.1
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr19_-_31765027 0.87 ENSMUST00000065067.6
protein kinase, cGMP-dependent, type I
chr5_+_108132885 0.85 ENSMUST00000047677.7
coiled-coil domain containing 18
chr11_+_105292637 0.84 ENSMUST00000100335.3
ENSMUST00000021038.4
mannose receptor, C type 2
chr6_+_119175247 0.84 ENSMUST00000112777.2
ENSMUST00000073909.5
DCP1 decapping enzyme homolog B (S. cerevisiae)
chr5_+_26904682 0.83 ENSMUST00000120555.1
dipeptidylpeptidase 6
chr6_+_125071277 0.83 ENSMUST00000140346.2
ENSMUST00000171989.1
lysophosphatidic acid receptor 5
chr9_+_107554633 0.82 ENSMUST00000010211.4
Ras association (RalGDS/AF-6) domain family member 1
chr11_+_71750680 0.81 ENSMUST00000021168.7
WSC domain containing 1
chr5_+_81021583 0.79 ENSMUST00000121707.1
latrophilin 3
chr17_+_35135463 0.78 ENSMUST00000173535.1
ENSMUST00000173952.1
BCL2-associated athanogene 6
chr17_+_24038144 0.78 ENSMUST00000059482.5
protease, serine, 27
chr17_+_48932368 0.78 ENSMUST00000046254.2
leucine rich repeat and fibronectin type III domain containing 2
chr17_+_8525369 0.78 ENSMUST00000115715.1
phosphodiesterase 10A
chr18_+_22345089 0.77 ENSMUST00000120223.1
ENSMUST00000097655.3
additional sex combs like 3 (Drosophila)
chr19_-_46044914 0.76 ENSMUST00000026252.7
LIM domain binding 1
chr1_+_87470258 0.76 ENSMUST00000027476.4
RIKEN cDNA 3110079O15 gene
chr8_+_110721462 0.76 ENSMUST00000052457.8
metastasis suppressor 1-like
chr12_-_3357012 0.76 ENSMUST00000180719.1
predicted gene, 26520
chr19_-_50678642 0.75 ENSMUST00000072685.6
ENSMUST00000164039.2
VPS10 domain receptor protein SORCS 1
chr3_-_105932664 0.75 ENSMUST00000098758.2
RIKEN cDNA I830077J02 gene
chr3_-_30509752 0.74 ENSMUST00000172697.1
MDS1 and EVI1 complex locus
chr5_+_86071734 0.74 ENSMUST00000031171.7
signal transducing adaptor family member 1
chr3_+_28263563 0.73 ENSMUST00000160307.2
ENSMUST00000159680.2
ENSMUST00000160518.1
ENSMUST00000162485.1
ENSMUST00000159308.1
ENSMUST00000162777.1
ENSMUST00000161964.1
TRAF2 and NCK interacting kinase
chr3_+_105904377 0.73 ENSMUST00000000574.1
adenosine A3 receptor
chr11_-_76468396 0.73 ENSMUST00000065028.7
active BCR-related gene
chr17_+_78508063 0.72 ENSMUST00000024880.9
vitrin
chr5_-_137613759 0.72 ENSMUST00000155251.1
ENSMUST00000124693.1
procollagen C-endopeptidase enhancer protein
chr19_-_4615453 0.71 ENSMUST00000053597.2
leucine rich repeat and fibronectin type III domain containing 4
chr10_+_128225830 0.70 ENSMUST00000026455.7
major intrinsic protein of eye lens fiber
chr8_-_104631312 0.70 ENSMUST00000034351.6
Ras-related associated with diabetes
chr3_+_103074009 0.69 ENSMUST00000090715.6
adenosine monophosphate deaminase 1
chr19_+_27217011 0.68 ENSMUST00000164746.1
ENSMUST00000172302.1
very low density lipoprotein receptor
chr7_+_31059342 0.68 ENSMUST00000039775.7
leucine-rich repeat LGI family, member 4
chr1_-_171059390 0.68 ENSMUST00000164044.1
ENSMUST00000169017.1
Fc receptor, IgG, low affinity III
chr18_+_65581704 0.68 ENSMUST00000182979.1
zinc finger protein 532
chr9_-_44251464 0.67 ENSMUST00000034618.4
PDZ domain containing 3
chr9_+_120092106 0.66 ENSMUST00000048777.2
chemokine (C-C motif) receptor 8
chr13_+_91461050 0.66 ENSMUST00000004094.8
ENSMUST00000042122.8
single-stranded DNA binding protein 2
chr2_+_156421048 0.66 ENSMUST00000109574.1
erythrocyte protein band 4.1-like 1
chr10_+_80264942 0.65 ENSMUST00000105362.1
ENSMUST00000105361.3
DAZ associated protein 1
chr2_+_156421083 0.65 ENSMUST00000125153.2
ENSMUST00000103136.1
ENSMUST00000109577.2
erythrocyte protein band 4.1-like 1
chr19_-_53464721 0.64 ENSMUST00000180489.1
RIKEN cDNA 5830416P10 gene
chr9_+_112227443 0.63 ENSMUST00000161216.1
RIKEN cDNA 2310075C17 gene
chr18_-_32559914 0.63 ENSMUST00000174000.1
ENSMUST00000174459.1
glycophorin C
chr4_+_48045144 0.63 ENSMUST00000030025.3
nuclear receptor subfamily 4, group A, member 3
chr12_-_86079019 0.63 ENSMUST00000003687.6
transforming growth factor, beta 3
chr2_+_147364989 0.62 ENSMUST00000109968.2
paired box gene 1
chr5_-_67847360 0.62 ENSMUST00000072971.6
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr8_+_104340594 0.62 ENSMUST00000034343.4
CKLF-like MARVEL transmembrane domain containing 3
chr5_+_143651222 0.61 ENSMUST00000110727.1
cytohesin 3
chr17_+_8849974 0.61 ENSMUST00000115720.1
phosphodiesterase 10A
chr19_-_46039621 0.61 ENSMUST00000056931.7
LIM domain binding 1
chr3_-_52104891 0.61 ENSMUST00000121440.1
mastermind like 3 (Drosophila)
chrX_+_56731779 0.61 ENSMUST00000023854.3
ENSMUST00000114769.2
four and a half LIM domains 1
chr19_-_46045194 0.60 ENSMUST00000156585.1
ENSMUST00000152946.1
LIM domain binding 1
chr11_+_71749914 0.60 ENSMUST00000150531.1
WSC domain containing 1
chr4_-_133874682 0.59 ENSMUST00000168974.2
ribosomal protein S6 kinase polypeptide 1
chr1_-_149961230 0.59 ENSMUST00000070200.8
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr1_-_75278345 0.58 ENSMUST00000039534.4
regulated endocrine-specific protein 18

Network of associatons between targets according to the STRING database.

First level regulatory network of Epas1_Bcl3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 14.4 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
1.6 7.9 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
1.4 5.8 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
1.2 3.6 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
1.2 3.6 GO:2001076 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.9 2.8 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.8 4.2 GO:0046882 negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.7 2.8 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.6 2.5 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.6 3.0 GO:0031444 regulation of twitch skeletal muscle contraction(GO:0014724) slow-twitch skeletal muscle fiber contraction(GO:0031444)
0.6 2.9 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.6 2.3 GO:0006566 threonine metabolic process(GO:0006566)
0.6 1.7 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.6 2.8 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.5 12.6 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.5 3.2 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.5 1.5 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.5 4.4 GO:0032264 IMP salvage(GO:0032264)
0.5 4.3 GO:0010587 miRNA catabolic process(GO:0010587)
0.4 1.3 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.4 1.7 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.4 4.4 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.4 1.9 GO:0097167 circadian regulation of translation(GO:0097167)
0.4 1.8 GO:0072675 osteoclast fusion(GO:0072675)
0.3 3.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.3 1.0 GO:0070846 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.3 5.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 1.2 GO:0030070 insulin processing(GO:0030070)
0.3 2.4 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.3 1.5 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.3 1.5 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.3 13.5 GO:0032094 response to food(GO:0032094)
0.3 1.2 GO:0035910 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.3 1.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 2.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.3 3.7 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.3 1.3 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.2 3.0 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.2 1.5 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.2 0.7 GO:1902226 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.2 1.2 GO:0034436 glycoprotein transport(GO:0034436)
0.2 0.9 GO:0061743 motor learning(GO:0061743)
0.2 0.9 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 0.7 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.2 0.9 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.2 2.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.2 0.6 GO:0003032 detection of oxygen(GO:0003032) negative regulation of macrophage cytokine production(GO:0010936)
0.2 1.0 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.2 1.0 GO:0050915 sensory perception of sour taste(GO:0050915)
0.2 1.0 GO:0035063 nuclear speck organization(GO:0035063)
0.2 3.3 GO:0035988 chondrocyte proliferation(GO:0035988)
0.2 2.1 GO:0097264 self proteolysis(GO:0097264)
0.2 0.8 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.2 0.2 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.2 1.9 GO:0043312 neutrophil degranulation(GO:0043312)
0.2 0.5 GO:0052564 response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.2 0.7 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.2 0.9 GO:1902608 negative regulation of inositol phosphate biosynthetic process(GO:0010920) regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.2 0.5 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.2 3.6 GO:0046685 response to activity(GO:0014823) response to arsenic-containing substance(GO:0046685)
0.2 0.5 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.2 0.3 GO:0097048 dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668)
0.1 10.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 1.0 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.1 0.7 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 4.0 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 2.1 GO:0006968 cellular defense response(GO:0006968)
0.1 2.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.1 0.7 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.5 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1 0.9 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.1 1.3 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.1 1.2 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.1 1.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.4 GO:0015819 lysine transport(GO:0015819)
0.1 1.1 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 0.9 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.6 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 1.5 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.1 0.4 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.1 0.6 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 1.3 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919)
0.1 0.8 GO:1904378 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1 1.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.4 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.5 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.7 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 2.0 GO:0045953 negative regulation of natural killer cell mediated cytotoxicity(GO:0045953)
0.1 0.2 GO:0009957 epidermal cell fate specification(GO:0009957)
0.1 2.9 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.1 0.5 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.6 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.2 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1 0.6 GO:0048102 autophagic cell death(GO:0048102)
0.1 1.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 2.7 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.1 0.2 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.1 0.9 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.1 0.9 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.3 GO:1903375 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) trigeminal ganglion development(GO:0061551) facioacoustic ganglion development(GO:1903375)
0.1 0.7 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 0.6 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 2.0 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.1 1.1 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.1 GO:0003274 endocardial cushion fusion(GO:0003274) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.5 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.9 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 1.4 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 0.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.8 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.5 GO:0038166 angiotensin-activated signaling pathway(GO:0038166) receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 1.1 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.6 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.1 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.1 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.2 GO:0071351 interleukin-18-mediated signaling pathway(GO:0035655) cellular response to interleukin-18(GO:0071351)
0.0 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.2 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.4 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.4 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 7.2 GO:0030833 regulation of actin filament polymerization(GO:0030833)
0.0 2.7 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.2 GO:0061056 sclerotome development(GO:0061056)
0.0 0.3 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.2 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.7 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.5 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.4 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 1.1 GO:0001893 maternal placenta development(GO:0001893)
0.0 0.9 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.9 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 1.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.8 GO:0022011 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.6 GO:0034508 centromere complex assembly(GO:0034508)
0.0 2.3 GO:0043488 regulation of mRNA stability(GO:0043488)
0.0 1.1 GO:1901998 toxin transport(GO:1901998)
0.0 0.2 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.8 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.0 2.9 GO:0007338 single fertilization(GO:0007338)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 2.7 GO:0030218 erythrocyte differentiation(GO:0030218)
0.0 1.3 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.4 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.0 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.5 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 0.1 GO:0061042 vascular wound healing(GO:0061042)
0.0 1.2 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.5 GO:0009409 response to cold(GO:0009409)
0.0 0.0 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.0 0.8 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.5 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 3.1 GO:0032496 response to lipopolysaccharide(GO:0032496)
0.0 1.6 GO:0006165 nucleoside diphosphate phosphorylation(GO:0006165)
0.0 0.9 GO:0030239 myofibril assembly(GO:0030239)
0.0 1.8 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 1.0 GO:0017148 negative regulation of translation(GO:0017148)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 8.6 GO:0071953 elastic fiber(GO:0071953)
1.4 4.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
1.1 5.3 GO:0042583 chromaffin granule(GO:0042583)
0.8 5.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.7 2.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.4 1.2 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.4 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.4 1.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 1.0 GO:0099569 presynaptic cytoskeleton(GO:0099569)
0.2 0.7 GO:0046691 intracellular canaliculus(GO:0046691)
0.2 1.0 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.2 3.2 GO:0031143 pseudopodium(GO:0031143)
0.2 6.0 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.8 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.7 GO:0097208 alveolar lamellar body(GO:0097208)
0.1 0.5 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.1 3.0 GO:0005859 muscle myosin complex(GO:0005859) myosin filament(GO:0032982)
0.1 0.8 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 4.7 GO:0097440 apical dendrite(GO:0097440)
0.1 3.1 GO:0031430 M band(GO:0031430)
0.1 1.3 GO:0016600 flotillin complex(GO:0016600)
0.1 0.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 1.1 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 2.3 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.1 2.0 GO:0031672 A band(GO:0031672)
0.1 1.5 GO:0032433 filopodium tip(GO:0032433)
0.1 0.2 GO:0030312 external encapsulating structure(GO:0030312)
0.1 3.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 4.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 1.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 0.2 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.0 0.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 2.1 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 4.9 GO:0030018 Z disc(GO:0030018)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.4 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 1.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.5 GO:0000791 euchromatin(GO:0000791)
0.0 2.5 GO:0005811 lipid particle(GO:0005811)
0.0 1.8 GO:0042383 sarcolemma(GO:0042383)
0.0 3.0 GO:0036126 sperm flagellum(GO:0036126)
0.0 7.7 GO:0045121 membrane raft(GO:0045121) membrane microdomain(GO:0098857)
0.0 3.0 GO:0000922 spindle pole(GO:0000922)
0.0 3.4 GO:0043204 perikaryon(GO:0043204)
0.0 1.3 GO:0031594 neuromuscular junction(GO:0031594)
0.0 1.2 GO:0031201 SNARE complex(GO:0031201)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 3.2 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.0 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 9.2 GO:0005635 nuclear envelope(GO:0005635)
0.0 0.5 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 3.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.9 GO:0005844 polysome(GO:0005844)
0.0 0.8 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.3 GO:0033643 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.0 0.4 GO:0002102 podosome(GO:0002102)
0.0 0.5 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.9 GO:0031519 PcG protein complex(GO:0031519)
0.0 1.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.6 GO:0016459 myosin complex(GO:0016459)
0.0 4.1 GO:0016607 nuclear speck(GO:0016607)
0.0 1.6 GO:0001726 ruffle(GO:0001726)
0.0 1.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.9 GO:0071013 catalytic step 2 spliceosome(GO:0071013)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 12.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
2.4 9.8 GO:0004974 leukotriene receptor activity(GO:0004974)
1.1 3.2 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.7 5.2 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.7 2.9 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.5 4.4 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.5 4.2 GO:0034711 inhibin binding(GO:0034711)
0.5 14.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.4 5.3 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.4 1.2 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.4 1.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.4 1.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.3 0.9 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.3 1.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.2 1.2 GO:0051373 FATZ binding(GO:0051373)
0.2 1.0 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.2 0.7 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 0.9 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.2 2.5 GO:0030274 LIM domain binding(GO:0030274)
0.2 0.8 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.2 1.3 GO:0001595 angiotensin receptor activity(GO:0001595)
0.2 3.6 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.2 0.7 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.2 5.1 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.2 0.9 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.2 1.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.2 0.5 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.2 3.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.1 1.5 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 3.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 3.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 0.7 GO:0019770 IgG receptor activity(GO:0019770)
0.1 8.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 0.9 GO:0048495 Roundabout binding(GO:0048495)
0.1 0.4 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 3.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.1 0.7 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.1 1.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.1 0.9 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.8 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.9 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 3.4 GO:0043394 proteoglycan binding(GO:0043394)
0.1 1.0 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 1.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.4 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) L-lysine transmembrane transporter activity(GO:0015189)
0.1 1.9 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 1.1 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.2 GO:0071820 N-box binding(GO:0071820)
0.1 0.5 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 5.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 3.3 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.7 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 1.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.1 1.1 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 0.4 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.1 0.4 GO:0004985 opioid receptor activity(GO:0004985)
0.1 2.8 GO:0045182 translation regulator activity(GO:0045182)
0.1 1.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.1 GO:0035613 RNA stem-loop binding(GO:0035613)
0.1 0.2 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158)
0.1 0.2 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.7 GO:0015250 water channel activity(GO:0015250)
0.0 2.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.8 GO:0015643 toxic substance binding(GO:0015643)
0.0 2.9 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 2.1 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 2.3 GO:0070888 E-box binding(GO:0070888)
0.0 3.2 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.8 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.9 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.5 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 3.7 GO:0005178 integrin binding(GO:0005178)
0.0 2.0 GO:0043621 protein self-association(GO:0043621)
0.0 0.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.5 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 1.2 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 1.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.5 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 0.9 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 1.4 GO:0005080 protein kinase C binding(GO:0005080)
0.0 1.6 GO:0019905 syntaxin binding(GO:0019905)
0.0 1.3 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 3.1 GO:0004386 helicase activity(GO:0004386)
0.0 1.7 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.7 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.7 GO:0035064 methylated histone binding(GO:0035064)
0.0 7.0 GO:0008047 enzyme activator activity(GO:0008047)
0.0 0.2 GO:0005384 manganese ion transmembrane transporter activity(GO:0005384)
0.0 0.5 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.5 GO:0002020 protease binding(GO:0002020)
0.0 0.0 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.6 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 7.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 2.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 1.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 4.9 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 6.8 PID P73PATHWAY p73 transcription factor network
0.1 4.0 PID LKB1 PATHWAY LKB1 signaling events
0.1 2.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.8 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 1.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 7.1 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.7 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.8 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.2 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 4.6 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.7 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.5 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.8 PID IFNG PATHWAY IFN-gamma pathway
0.0 1.1 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 0.9 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 1.0 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.7 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.8 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway
0.0 0.8 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID SHP2 PATHWAY SHP2 signaling
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.4 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.2 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 4.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.3 14.4 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.3 11.3 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.2 4.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.1 3.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 4.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 3.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 4.5 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.1 1.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 2.6 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1 3.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 2.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 2.5 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.1 2.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 0.9 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.1 3.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 0.7 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 1.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 2.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.1 0.8 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 2.0 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.7 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 1.8 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.7 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 1.9 REACTOME EXTRACELLULAR MATRIX ORGANIZATION Genes involved in Extracellular matrix organization
0.0 1.2 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 0.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.6 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 1.2 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.9 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.8 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.8 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.8 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.7 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 2.8 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.2 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.1 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.2 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling