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avrg: GSE58827: Dynamics of the Mouse Liver

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Results for Ar

Z-value: 1.66

Motif logo

Transcription factors associated with Ar

Gene Symbol Gene ID Gene Info
ENSMUSG00000046532.7 androgen receptor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Armm10_v2_chrX_+_98149666_98149721-0.401.5e-02Click!

Activity profile of Ar motif

Sorted Z-values of Ar motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_28563362 13.99 ENSMUST00000028161.5
carboxyl ester lipase
chr9_+_110419750 6.63 ENSMUST00000035061.6
neutrophilic granule protein
chr10_+_75566257 6.61 ENSMUST00000129232.1
ENSMUST00000143792.1
gamma-glutamyltransferase 1
chr5_-_134915512 5.76 ENSMUST00000008987.4
claudin 13
chr8_-_107065632 4.99 ENSMUST00000034393.5
transmembrane emp24 protein transport domain containing 6
chr8_+_94179089 4.80 ENSMUST00000034215.6
metallothionein 1
chr6_-_116461024 4.16 ENSMUST00000164547.1
ENSMUST00000170186.1
arachidonate 5-lipoxygenase
chr17_+_29114142 4.15 ENSMUST00000141797.1
ENSMUST00000132262.1
ENSMUST00000141239.1
ENSMUST00000138816.1
predicted gene 16194
chr14_+_51853699 4.00 ENSMUST00000169070.1
ENSMUST00000074477.6
eosinophil-associated, ribonuclease A family, member 6
chr4_-_137409777 3.69 ENSMUST00000024200.6
predicted gene 13011
chr6_-_116461151 3.62 ENSMUST00000026795.6
arachidonate 5-lipoxygenase
chr11_-_116076986 3.60 ENSMUST00000153408.1
unc-13 homolog D (C. elegans)
chr5_-_145720124 3.53 ENSMUST00000094111.4
cytochrome P450, family 3, subfamily a, polypeptide 41A
chr2_-_32387760 3.45 ENSMUST00000050785.8
lipocalin 2
chr17_-_31144271 3.41 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr5_-_145584723 3.39 ENSMUST00000075837.6
cytochrome P450, family 3, subfamily a, polypeptide 41B
chr7_-_4397705 3.37 ENSMUST00000108590.2
glycoprotein 6 (platelet)
chr11_+_104577281 3.17 ENSMUST00000106956.3
myosin, light polypeptide 4
chr11_+_69098937 3.07 ENSMUST00000021271.7
period circadian clock 1
chr11_+_104576965 3.03 ENSMUST00000106957.1
myosin, light polypeptide 4
chr17_+_47593516 2.91 ENSMUST00000182874.1
cyclin D3
chr6_-_122801639 2.87 ENSMUST00000165884.1
solute carrier family 2 (facilitated glucose transporter), member 3
chr2_-_164779721 2.84 ENSMUST00000103095.4
troponin C2, fast
chr6_-_69243445 2.78 ENSMUST00000101325.3
immunoglobulin kappa chain variable 4-71
chr11_-_69948145 2.71 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
solute carrier family 2 (facilitated glucose transporter), member 4
chr2_-_62483637 2.69 ENSMUST00000136686.1
ENSMUST00000102733.3
glucagon
chr4_-_44710408 2.66 ENSMUST00000134968.2
ENSMUST00000173821.1
ENSMUST00000174319.1
ENSMUST00000173733.1
ENSMUST00000172866.1
ENSMUST00000165417.2
ENSMUST00000107825.2
ENSMUST00000102932.3
ENSMUST00000107827.2
ENSMUST00000107826.2
paired box gene 5
chr15_-_75111684 2.56 ENSMUST00000100542.3
lymphocyte antigen 6 complex, locus C2
chr11_-_70352029 2.54 ENSMUST00000019068.6
arachidonate 15-lipoxygenase
chr14_-_60197173 2.51 ENSMUST00000131670.1
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr1_-_90153396 2.50 ENSMUST00000113094.2
IQ motif containing with AAA domain
chr8_+_21734490 2.50 ENSMUST00000080533.5
defensin, alpha, 24
chr15_-_101491509 2.42 ENSMUST00000023718.7
RIKEN cDNA 5430421N21 gene
chr3_-_98814434 2.36 ENSMUST00000029463.6
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6
chr1_+_170644523 2.32 ENSMUST00000046792.8
olfactomedin-like 2B
chr17_-_7352696 2.21 ENSMUST00000115747.1
tubulin tyrosine ligase-like family, member 2
chr2_-_163087770 2.21 ENSMUST00000094653.4
gametocyte specific factor 1-like
chr3_-_116253467 2.16 ENSMUST00000090473.5
G-protein coupled receptor 88
chr11_+_58379036 2.08 ENSMUST00000013787.4
ENSMUST00000108826.2
LY6/PLAUR domain containing 8
chr9_-_123968683 2.08 ENSMUST00000026911.4
chemokine (C-C motif) receptor 1
chr14_-_56262233 2.06 ENSMUST00000015581.4
granzyme B
chr16_+_32756336 2.01 ENSMUST00000135753.1
mucin 4
chr8_-_72009619 1.92 ENSMUST00000003574.4
cytochrome P450, family 4, subfamily f, polypeptide 18
chr1_+_172555932 1.92 ENSMUST00000061835.3
V-set and immunoglobulin domain containing 8
chr4_-_49408042 1.87 ENSMUST00000081541.2
acyl-coenzyme A amino acid N-acyltransferase 2
chr17_-_43543639 1.86 ENSMUST00000178772.1
ankyrin repeat domain 66
chr6_+_29433248 1.85 ENSMUST00000101617.2
ENSMUST00000065090.5
filamin C, gamma
chr8_+_21134610 1.83 ENSMUST00000098898.4
predicted gene 15284
chr13_+_99100698 1.81 ENSMUST00000181742.1
predicted gene 807
chr8_-_64693027 1.79 ENSMUST00000048967.7
carboxypeptidase E
chr10_-_117282262 1.79 ENSMUST00000092163.7
lysozyme 2
chr8_-_21594508 1.77 ENSMUST00000110749.3
predicted gene 7861
chr13_+_108316332 1.76 ENSMUST00000051594.5
DEP domain containing 1B
chr6_-_136922169 1.74 ENSMUST00000032343.6
endoplasmic reticulum protein 27
chr15_+_80097866 1.74 ENSMUST00000143928.1
synaptogyrin 1
chr2_-_156839790 1.73 ENSMUST00000134838.1
ENSMUST00000137463.1
ENSMUST00000149275.2
predicted gene 14230
chr13_-_37049203 1.70 ENSMUST00000037491.8
coagulation factor XIII, A1 subunit
chr13_+_108316395 1.70 ENSMUST00000171178.1
DEP domain containing 1B
chr11_+_96931387 1.69 ENSMUST00000107633.1
proline rich 15-like
chr6_-_123289862 1.65 ENSMUST00000032239.4
ENSMUST00000177367.1
C-type lectin domain family 4, member e
chr6_+_29433131 1.64 ENSMUST00000090474.4
filamin C, gamma
chr16_-_92697315 1.63 ENSMUST00000168195.1
ENSMUST00000113956.3
runt related transcription factor 1
chr8_-_21096050 1.62 ENSMUST00000077452.3
predicted gene 14851
chr8_+_123186235 1.61 ENSMUST00000019422.4
dipeptidase 1 (renal)
chr9_+_119052863 1.60 ENSMUST00000131647.1
villin-like
chr5_+_44100442 1.60 ENSMUST00000072800.4
predicted gene 16401
chr12_+_84100654 1.59 ENSMUST00000056822.3
acyl-CoA thioesterase 6
chr12_-_28582515 1.57 ENSMUST00000110917.1
ENSMUST00000020965.7
allantoicase
chr14_+_65806066 1.56 ENSMUST00000139644.1
PDZ binding kinase
chr15_-_41869703 1.56 ENSMUST00000054742.5
actin-binding Rho activating protein
chr8_+_110919916 1.55 ENSMUST00000117534.1
ENSMUST00000034197.4
ST3 beta-galactoside alpha-2,3-sialyltransferase 2
chr17_+_17887840 1.55 ENSMUST00000054871.5
ENSMUST00000064068.4
formyl peptide receptor 3
formyl peptide receptor 2
chr15_-_103252810 1.52 ENSMUST00000154510.1
nuclear factor, erythroid derived 2
chr7_+_28982832 1.52 ENSMUST00000085835.6
mitogen-activated protein kinase kinase kinase kinase 1
chr8_+_21655780 1.52 ENSMUST00000079528.5
defensin, alpha, 17
chr6_+_127887582 1.48 ENSMUST00000032501.4
tetraspanin 11
chr17_+_35567450 1.46 ENSMUST00000044326.4
RIKEN cDNA 2300002M23 gene
chrX_+_49463926 1.46 ENSMUST00000130558.1
Rho GTPase activating protein 36
chr7_+_43440782 1.44 ENSMUST00000040227.1
claudin domain containing 2
chr8_-_46211284 1.43 ENSMUST00000034049.4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr8_-_21456560 1.42 ENSMUST00000110752.3
predicted gene 7849
chr8_+_21287409 1.42 ENSMUST00000098893.3
defensin, alpha, 3
chr17_+_47593444 1.41 ENSMUST00000182209.1
cyclin D3
chr5_+_122206792 1.41 ENSMUST00000145854.1
hydrogen voltage-gated channel 1
chr2_-_129297205 1.40 ENSMUST00000052708.6
cytoskeleton associated protein 2-like
chr2_+_14873656 1.39 ENSMUST00000114718.1
ENSMUST00000114719.1
calcium channel, voltage-dependent, beta 2 subunit
chr4_-_149137536 1.39 ENSMUST00000176124.1
ENSMUST00000177408.1
ENSMUST00000105695.1
ENSMUST00000030813.3
apoptosis-inducing, TAF9-like domain 1
chr8_-_21703642 1.36 ENSMUST00000071886.6
cDNA sequence AY761184
chr8_-_104624266 1.36 ENSMUST00000163783.2
cadherin 16
chr8_+_21055047 1.35 ENSMUST00000098899.3
defensin, alpha, 23
chr19_-_45812291 1.30 ENSMUST00000086993.4
Kv channel-interacting protein 2
chr17_+_56764738 1.29 ENSMUST00000007747.8
dihydrouridine synthase 3-like (S. cerevisiae)
chr4_+_150927918 1.29 ENSMUST00000139826.1
ENSMUST00000116257.1
tumor necrosis factor receptor superfamily, member 9
chr8_+_21191614 1.28 ENSMUST00000098896.4
defensin, alpha, related sequence 7
chr1_-_14755966 1.27 ENSMUST00000027062.5
musculin
chr11_-_87108656 1.27 ENSMUST00000051395.8
proline rich 11
chr8_+_84148252 1.27 ENSMUST00000093375.4
RIKEN cDNA 4930432K21 gene
chr2_-_29869785 1.20 ENSMUST00000047607.1
RIKEN cDNA 2600006K01 gene
chr11_-_69822144 1.19 ENSMUST00000045771.6
sperm maturation 1
chr6_+_49036518 1.18 ENSMUST00000031840.7
glycoprotein (transmembrane) nmb
chr3_+_152165374 1.18 ENSMUST00000181854.1
RIKEN cDNA D630002J18 gene
chr3_-_129969989 1.18 ENSMUST00000146340.1
coiled-coil domain containing 109B
chr4_+_11123950 1.17 ENSMUST00000142297.1
predicted gene 11827
chrX_+_134308084 1.16 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
centromere protein I
chr7_+_12922290 1.16 ENSMUST00000108539.1
ENSMUST00000004554.7
ENSMUST00000147435.1
ENSMUST00000137329.1
ribosomal protein S5
chr12_+_104406704 1.12 ENSMUST00000021506.5
serine (or cysteine) peptidase inhibitor, clade A, member 3N
chr7_-_45092198 1.12 ENSMUST00000140449.1
ENSMUST00000117546.1
ENSMUST00000019683.3
reticulocalbin 3, EF-hand calcium binding domain
chr6_-_69400097 1.11 ENSMUST00000177795.1
immunoglobulin kappa variable 4-62
chr2_+_25423234 1.10 ENSMUST00000134259.1
ENSMUST00000100320.4
fucosyltransferase 7
chr2_+_152427639 1.10 ENSMUST00000128737.1
RIKEN cDNA 6820408C15 gene
chr2_+_26319741 1.09 ENSMUST00000066889.6
G-protein signalling modulator 1 (AGS3-like, C. elegans)
chr5_+_141856692 1.09 ENSMUST00000074546.6
sidekick homolog 1 (chicken)
chr2_-_24935148 1.08 ENSMUST00000102935.3
ENSMUST00000133934.1
ENSMUST00000028349.7
arrestin domain containing 1
chr11_-_106160708 1.08 ENSMUST00000106875.1
LIM domain containing 2
chr2_-_122298165 1.06 ENSMUST00000053734.5
dual oxidase 2
chr17_-_45549655 1.06 ENSMUST00000180252.1
transmembrane protein 151B
chr10_+_75954514 1.05 ENSMUST00000099577.3
predicted gene 5134
chr11_+_69964758 1.04 ENSMUST00000108597.1
ENSMUST00000060651.5
ENSMUST00000108596.1
claudin 7
chr5_+_25246775 1.04 ENSMUST00000144971.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 11
chr11_+_98386450 1.02 ENSMUST00000041301.7
phenylethanolamine-N-methyltransferase
chr11_+_94936224 1.02 ENSMUST00000001547.7
collagen, type I, alpha 1
chr9_-_20959785 1.02 ENSMUST00000177754.1
DNA methyltransferase (cytosine-5) 1
chr11_+_108395288 1.02 ENSMUST00000000049.5
apolipoprotein H
chr7_-_44974781 1.01 ENSMUST00000063761.7
carnitine palmitoyltransferase 1c
chr8_+_71406003 1.01 ENSMUST00000119976.1
ENSMUST00000120725.1
ankyrin repeat and LEM domain containing 1
chr2_+_136057927 1.01 ENSMUST00000057503.6
lysosomal-associated membrane protein family, member 5
chr6_+_34476207 1.00 ENSMUST00000045372.5
ENSMUST00000138668.1
ENSMUST00000139067.1
2,3-bisphosphoglycerate mutase
chr5_+_17574726 1.00 ENSMUST00000169603.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr2_-_150179679 0.98 ENSMUST00000099418.2
predicted gene 10770
chr4_+_116708571 0.98 ENSMUST00000106462.2
ENSMUST00000138305.1
ENSMUST00000125671.1
ENSMUST00000130828.1
coiled-coil domain containing 163
chr10_-_32410335 0.98 ENSMUST00000092603.4
Na+/K+ transporting ATPase interacting 2
chr5_-_140321524 0.97 ENSMUST00000031534.6
MAD1 mitotic arrest deficient 1-like 1
chr10_-_86732409 0.96 ENSMUST00000070435.4
fatty acid binding protein 3, muscle and heart, pseudogene 1
chr2_-_132029845 0.96 ENSMUST00000028814.8
Ras association (RalGDS/AF-6) domain family member 2
chr6_+_5725639 0.95 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
dynein cytoplasmic 1 intermediate chain 1
chr1_+_91540553 0.95 ENSMUST00000027538.7
ankyrin repeat and SOCS box-containing 1
chr7_-_81566939 0.95 ENSMUST00000042318.5
fibronectin type III and SPRY domain containing 2
chr2_+_109280738 0.94 ENSMUST00000028527.7
kinesin family member 18A
chr16_-_45693658 0.94 ENSMUST00000114562.2
ENSMUST00000036617.7
transmembrane serine protease 7
chr7_-_45092130 0.92 ENSMUST00000148175.1
reticulocalbin 3, EF-hand calcium binding domain
chr8_+_94745590 0.92 ENSMUST00000034231.3
chemokine (C-C motif) ligand 22
chr4_-_149909719 0.91 ENSMUST00000105685.1
splA/ryanodine receptor domain and SOCS box containing 1
chr7_+_16992708 0.91 ENSMUST00000094805.4
coiled-coil domain containing 8
chr3_-_144760841 0.91 ENSMUST00000059091.5
chloride channel calcium activated 1
chr18_+_65580230 0.90 ENSMUST00000049016.5
ENSMUST00000183236.1
zinc finger protein 532
chr17_+_56256793 0.89 ENSMUST00000060253.3
feminization 1 homolog a (C. elegans)
chr8_+_95703037 0.89 ENSMUST00000073139.7
ENSMUST00000080666.7
N-myc downstream regulated gene 4
chr11_-_75439551 0.88 ENSMUST00000128330.1
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr1_-_133801031 0.88 ENSMUST00000143567.1
ATPase, Ca++ transporting, plasma membrane 4
chr5_+_110879788 0.86 ENSMUST00000156290.2
ENSMUST00000040111.9
tetratricopeptide repeat domain 28
chr4_+_12906838 0.86 ENSMUST00000143186.1
ENSMUST00000183345.1
triple QxxK/R motif containing
chr1_-_163289214 0.86 ENSMUST00000183691.1
paired related homeobox 1
chr14_+_32159865 0.86 ENSMUST00000163336.1
ENSMUST00000169722.1
ENSMUST00000168385.1
nuclear receptor coactivator 4
chr15_-_85821733 0.85 ENSMUST00000064370.4
polycystic kidney disease (polycystin) and REJ (sperm receptor for egg jelly homolog, sea urchin)
chr1_+_174041933 0.84 ENSMUST00000052975.4
olfactory receptor 433
chr4_+_116708624 0.84 ENSMUST00000106463.1
coiled-coil domain containing 163
chr4_+_116708687 0.83 ENSMUST00000135499.1
coiled-coil domain containing 163
chr9_+_56865104 0.82 ENSMUST00000035661.5
chondroitin sulfate proteoglycan 4
chr4_+_135911808 0.81 ENSMUST00000068830.3
cannabinoid receptor 2 (macrophage)
chr14_-_32685246 0.80 ENSMUST00000096038.3
RIKEN cDNA 3425401B19 gene
chr11_-_98053415 0.80 ENSMUST00000017544.2
SH3 and cysteine rich domain 2
chr14_+_53683593 0.79 ENSMUST00000103663.4
T cell receptor alpha variable 4-4-DV10
chr7_-_46179929 0.79 ENSMUST00000033123.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr18_+_36679575 0.79 ENSMUST00000050476.4
ENSMUST00000036158.6
solute carrier family 35, member A4
chr1_-_170589791 0.78 ENSMUST00000161966.1
ENSMUST00000160456.1
nitric oxide synthase 1 (neuronal) adaptor protein
chr5_-_122697603 0.78 ENSMUST00000071235.4
predicted gene 10064
chr4_-_44704006 0.75 ENSMUST00000146335.1
paired box gene 5
chr17_-_36020525 0.75 ENSMUST00000174063.1
ENSMUST00000113760.3
histocompatibility 2, T region locus 24
chr17_-_47924460 0.74 ENSMUST00000113262.1
forkhead box P4
chr11_-_99155067 0.73 ENSMUST00000103134.3
chemokine (C-C motif) receptor 7
chr2_-_24935054 0.73 ENSMUST00000132074.1
arrestin domain containing 1
chr11_+_61208621 0.73 ENSMUST00000108716.1
ENSMUST00000019246.3
aldehyde dehydrogenase family 3, subfamily A1
chr10_+_128411616 0.72 ENSMUST00000096386.5
ENSMUST00000171342.1
ring finger protein 41
chr7_-_46672537 0.71 ENSMUST00000049298.7
tryptophan hydroxylase 1
chr2_-_126618655 0.71 ENSMUST00000028838.4
histidine decarboxylase
chr18_+_64254359 0.71 ENSMUST00000025477.7
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr11_-_33578933 0.71 ENSMUST00000020366.1
ENSMUST00000135350.1
gamma-aminobutyric acid (GABA) A receptor, pi
chr13_-_59675754 0.70 ENSMUST00000022039.5
ENSMUST00000095739.2
golgi membrane protein 1
chr2_+_158512796 0.70 ENSMUST00000099133.3
ENSMUST00000165398.1
Rho GTPase activating protein 40
chr14_+_66784523 0.69 ENSMUST00000071522.2
predicted gene 10032
chr14_-_6742332 0.69 ENSMUST00000163850.1
predicted gene 3636
chr4_-_111902754 0.69 ENSMUST00000102719.1
ENSMUST00000102721.1
solute carrier family 5 (sodium/glucose cotransporter), member 9
chrX_+_37804842 0.69 ENSMUST00000184866.1
ENSMUST00000179626.1
reproductive homeobox 5
chr5_+_47984571 0.68 ENSMUST00000174313.1
slit homolog 2 (Drosophila)
chr11_-_75439489 0.67 ENSMUST00000043696.2
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr2_-_118728430 0.66 ENSMUST00000102524.1
phospholipase C, beta 2
chr14_-_70331514 0.66 ENSMUST00000139284.1
solute carrier family 39 (zinc transporter), member 14
chr2_-_10130638 0.65 ENSMUST00000042290.7
inter-alpha trypsin inhibitor, heavy chain 2
chr6_+_135362931 0.65 ENSMUST00000032330.9
epithelial membrane protein 1
chr4_+_109978004 0.65 ENSMUST00000061187.3
doublesex and mab-3 related transcription factor like family A2
chr19_+_10937154 0.64 ENSMUST00000037261.3
G protein-coupled receptor 44
chr7_+_118600152 0.63 ENSMUST00000121744.1
transmembrane channel-like gene family 5
chr11_+_69125896 0.63 ENSMUST00000021268.2
arachidonate lipoxygenase 3
chr17_-_47924400 0.62 ENSMUST00000113263.1
ENSMUST00000097311.2
forkhead box P4
chr14_-_6875155 0.62 ENSMUST00000170465.2
predicted gene 3636
chr18_-_78057395 0.62 ENSMUST00000170760.2
sialic acid binding Ig-like lectin 15
chr3_-_30647793 0.62 ENSMUST00000029252.7
leucine rich repeat containing 34
chr1_-_144249134 0.62 ENSMUST00000172388.1
regulator of G-protein signaling 1
chr6_+_29279587 0.62 ENSMUST00000167131.1
family with sequence similarity 71, member F2
chr8_-_13254154 0.62 ENSMUST00000033825.4
ADP-ribosylhydrolase like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Ar

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.8 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
1.7 6.6 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
1.4 1.4 GO:2000277 positive regulation of oxidative phosphorylation uncoupler activity(GO:2000277)
1.0 14.0 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.8 2.5 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.8 6.6 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.7 4.8 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.6 1.9 GO:0042374 menaquinone metabolic process(GO:0009233) phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.6 3.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.6 2.9 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.5 1.6 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.5 2.2 GO:0061743 motor learning(GO:0061743)
0.5 3.4 GO:1901678 iron coordination entity transport(GO:1901678)
0.5 3.4 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.5 1.4 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.4 1.8 GO:0030070 insulin processing(GO:0030070)
0.4 0.9 GO:2000282 regulation of cellular amino acid biosynthetic process(GO:2000282)
0.4 2.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.4 3.6 GO:0002432 granuloma formation(GO:0002432)
0.4 2.7 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.3 1.0 GO:0042414 epinephrine metabolic process(GO:0042414)
0.3 2.0 GO:0002835 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.3 1.7 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.3 1.3 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.3 2.6 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.3 1.3 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.3 2.5 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.3 1.1 GO:0048850 hypophysis morphogenesis(GO:0048850)
0.3 0.8 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.3 0.5 GO:0051885 positive regulation of anagen(GO:0051885)
0.3 1.3 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.3 1.6 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.3 1.0 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.2 0.7 GO:2000412 lymphocyte migration into lymphoid organs(GO:0097021) positive regulation of thymocyte migration(GO:2000412) regulation of immunological synapse formation(GO:2000520) regulation of dendritic cell dendrite assembly(GO:2000547)
0.2 1.0 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.2 0.7 GO:0050924 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.2 4.4 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.2 1.0 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.2 1.0 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.2 0.5 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.2 0.5 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.2 0.7 GO:1990743 protein sialylation(GO:1990743)
0.2 4.0 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.2 1.7 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.2 0.8 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.2 1.7 GO:1904659 glucose transmembrane transport(GO:1904659)
0.2 1.3 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.2 0.6 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 0.5 GO:0009258 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.2 1.4 GO:0071294 cellular response to zinc ion(GO:0071294)
0.2 3.4 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.2 6.2 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.2 1.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1 1.6 GO:0000255 allantoin metabolic process(GO:0000255)
0.1 1.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.7 GO:0001692 histamine metabolic process(GO:0001692) histidine catabolic process(GO:0006548)
0.1 1.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 3.6 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.1 0.1 GO:1904959 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.1 1.8 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 1.4 GO:1901249 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.1 1.1 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.6 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 1.2 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 1.3 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.8 GO:0032056 positive regulation of translation in response to stress(GO:0032056)
0.1 0.6 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.1 0.7 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.1 0.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 2.7 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.1 0.8 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.1 0.5 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.3 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 0.7 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.1 1.6 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 0.4 GO:0035811 negative regulation of urine volume(GO:0035811)
0.1 0.7 GO:0051177 meiotic sister chromatid cohesion(GO:0051177)
0.1 0.7 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 1.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 0.4 GO:0009597 detection of virus(GO:0009597) positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.9 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.1 1.0 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.1 1.0 GO:0009437 carnitine metabolic process(GO:0009437)
0.1 0.3 GO:0050904 diapedesis(GO:0050904)
0.1 2.8 GO:0003009 skeletal muscle contraction(GO:0003009)
0.1 0.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.6 GO:2001204 regulation of osteoclast development(GO:2001204)
0.1 0.2 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 0.8 GO:0016322 neuron remodeling(GO:0016322)
0.1 1.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.9 GO:0048664 neuron fate determination(GO:0048664)
0.1 0.2 GO:1901994 negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.2 GO:0033189 response to vitamin A(GO:0033189)
0.1 0.9 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 1.2 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:0034616 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.0 0.9 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 3.3 GO:0048747 muscle fiber development(GO:0048747)
0.0 0.7 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 1.2 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.6 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.1 GO:0030473 nucleokinesis involved in cell motility in cerebral cortex radial glia guided migration(GO:0021817) nuclear migration along microtubule(GO:0030473)
0.0 0.9 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.3 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 1.2 GO:0034508 centromere complex assembly(GO:0034508)
0.0 0.4 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 2.0 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.6 GO:0032060 bleb assembly(GO:0032060)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 4.0 GO:0002377 immunoglobulin production(GO:0002377)
0.0 0.1 GO:0060025 regulation of synaptic activity(GO:0060025)
0.0 1.0 GO:0030539 male genitalia development(GO:0030539)
0.0 1.0 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.6 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.4 GO:0043486 histone exchange(GO:0043486)
0.0 0.3 GO:0042711 maternal behavior(GO:0042711)
0.0 1.6 GO:0032873 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.0 0.3 GO:0046641 positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.0 0.1 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.5 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 1.3 GO:0051693 actin filament capping(GO:0051693)
0.0 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) regulation of mitotic cell cycle DNA replication(GO:1903463) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.0 0.8 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 3.1 GO:0030177 positive regulation of Wnt signaling pathway(GO:0030177)
0.0 0.3 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.0 0.9 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.2 GO:0099515 actin filament-based transport(GO:0099515)
0.0 0.5 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.2 GO:2000253 adult feeding behavior(GO:0008343) positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0 0.2 GO:0072660 positive regulation of cell communication by electrical coupling(GO:0010650) maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.7 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.2 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.8 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.4 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.2 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.0 1.2 GO:0030317 sperm motility(GO:0030317)
0.0 0.4 GO:0072678 T cell migration(GO:0072678)
0.0 0.2 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.7 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.0 0.6 GO:0045604 regulation of epidermal cell differentiation(GO:0045604)
0.0 1.1 GO:0002028 regulation of sodium ion transport(GO:0002028)
0.0 0.8 GO:0050982 detection of mechanical stimulus(GO:0050982)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0044194 cytolytic granule(GO:0044194)
0.5 8.1 GO:0005641 nuclear envelope lumen(GO:0005641)
0.5 14.9 GO:0042588 zymogen granule(GO:0042588)
0.4 1.3 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.4 1.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.3 1.0 GO:0005584 collagen type I trimer(GO:0005584)
0.3 3.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.3 3.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.2 2.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.2 0.8 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 1.6 GO:0005577 fibrinogen complex(GO:0005577)
0.2 2.7 GO:0032593 insulin-responsive compartment(GO:0032593)
0.2 2.8 GO:0005861 troponin complex(GO:0005861)
0.2 0.9 GO:1990393 3M complex(GO:1990393)
0.1 1.0 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.1 1.8 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.7 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.1 0.6 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.1 1.6 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 1.8 GO:0031045 dense core granule(GO:0031045)
0.1 2.9 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.3 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.1 6.4 GO:0031672 A band(GO:0031672)
0.1 2.0 GO:0031528 microvillus membrane(GO:0031528)
0.1 7.0 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.9 GO:0044754 autolysosome(GO:0044754)
0.1 1.5 GO:0005614 interstitial matrix(GO:0005614)
0.1 3.1 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.4 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 1.0 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.7 GO:0098827 endoplasmic reticulum tubular network(GO:0071782) endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 2.6 GO:0031970 organelle envelope lumen(GO:0031970)
0.0 0.9 GO:0097228 sperm principal piece(GO:0097228)
0.0 1.0 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.6 GO:0042627 chylomicron(GO:0042627)
0.0 1.7 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:1990696 USH2 complex(GO:1990696)
0.0 5.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0030914 STAGA complex(GO:0030914)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 3.0 GO:0072562 blood microparticle(GO:0072562)
0.0 1.8 GO:0016528 sarcoplasm(GO:0016528)
0.0 0.3 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 3.1 GO:0001650 fibrillar center(GO:0001650)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 2.6 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.6 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 21.4 GO:0005615 extracellular space(GO:0005615)
0.0 5.0 GO:0005789 endoplasmic reticulum membrane(GO:0005789)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.0 GO:0004771 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
2.6 7.8 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
1.1 5.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.9 6.9 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.7 2.1 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.6 1.9 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
0.6 2.5 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.6 6.6 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.5 2.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.4 1.6 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.4 1.5 GO:0070052 collagen V binding(GO:0070052)
0.3 1.0 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.3 2.4 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.3 3.4 GO:0038064 collagen receptor activity(GO:0038064)
0.3 1.4 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.3 1.4 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.3 3.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 1.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 1.6 GO:0005124 scavenger receptor binding(GO:0005124)
0.3 1.0 GO:0070573 metallodipeptidase activity(GO:0070573)
0.2 1.0 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
0.2 0.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 0.7 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 1.7 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.2 1.0 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 0.8 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.2 0.6 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 1.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.2 0.6 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.2 0.5 GO:0070737 protein-glycine ligase activity, elongating(GO:0070737)
0.2 0.7 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.2 1.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.2 0.5 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)
0.2 1.4 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 1.2 GO:0045545 syndecan binding(GO:0045545)
0.1 1.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 1.6 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 6.2 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.8 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 1.8 GO:0003796 lysozyme activity(GO:0003796)
0.1 1.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.4 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.1 0.4 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 1.4 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.1 0.7 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 1.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 3.5 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 0.7 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 1.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.4 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.3 GO:0004915 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.1 0.7 GO:0048495 GTPase inhibitor activity(GO:0005095) Roundabout binding(GO:0048495)
0.1 0.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 2.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.1 GO:0030506 ankyrin binding(GO:0030506)
0.1 6.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 1.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.0 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.4 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.1 0.2 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.1 0.9 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 1.0 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.4 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 3.1 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.1 4.7 GO:0005507 copper ion binding(GO:0005507)
0.1 1.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 0.3 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.9 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 3.1 GO:0070888 E-box binding(GO:0070888)
0.0 1.1 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 1.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.6 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.6 GO:0043495 protein anchor(GO:0043495)
0.0 5.4 GO:0002020 protease binding(GO:0002020)
0.0 0.4 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.8 GO:0005351 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 1.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.9 GO:0008009 chemokine activity(GO:0008009)
0.0 0.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 4.9 GO:0004519 endonuclease activity(GO:0004519)
0.0 2.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.7 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.4 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.2 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.3 GO:0001727 lipid kinase activity(GO:0001727) diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.8 GO:0042605 peptide antigen binding(GO:0042605)
0.0 2.3 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0016805 dipeptidase activity(GO:0016805)
0.0 3.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.8 GO:0005518 collagen binding(GO:0005518)
0.0 3.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 2.2 GO:0003774 motor activity(GO:0003774)
0.0 0.7 GO:0005109 frizzled binding(GO:0005109)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.7 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.2 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 2.8 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.2 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.5 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 0.6 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 1.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 3.8 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.1 3.5 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.1 3.6 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 1.9 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.7 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 1.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 2.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.6 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.0 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 3.2 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.3 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 4.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.7 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.4 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.0 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.2 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.6 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.2 9.0 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.2 3.6 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 2.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 3.5 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 1.4 REACTOME DEFENSINS Genes involved in Defensins
0.1 1.6 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.1 3.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 1.8 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.4 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.1 3.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.1 1.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 0.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 0.8 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.1 0.6 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 0.7 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.4 REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS Genes involved in Interactions of Vpr with host cellular proteins
0.0 1.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 4.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.7 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 1.9 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.7 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 1.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 1.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.9 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.5 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.0 0.8 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 2.8 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.2 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.3 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.4 REACTOME GLUCOSE METABOLISM Genes involved in Glucose metabolism