avrg: GSE58827: Dynamics of the Mouse Liver

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
Klf8 Links Ensembl NCBI MGI UniProt	ENSMUSG00000041649.7	Kruppel-like factor 8

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Klf8	mm10_v2_chrX_+_153237748_153237748	-0.25	1.3e-01	Click!

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0048627	myoblast development(GO:0048627)
0.3	0.8	GO:0071314	cellular response to cocaine(GO:0071314)
0.3	0.8	GO:0002266	follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.2	0.9	GO:0034757	negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.2	0.6	GO:0060265	positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.2	1.1	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.2	0.5	GO:0007521	muscle cell fate determination(GO:0007521)
0.2	0.9	GO:1903278	positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.1	0.6	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.1	1.6	GO:0072615	interleukin-17 secretion(GO:0072615)
0.1	0.4	GO:0090327	cell communication by chemical coupling(GO:0010643) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.1	0.4	GO:0045077	negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1	0.1	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.1	0.6	GO:0051309	female meiosis chromosome separation(GO:0051309)
0.1	0.4	GO:1904954	canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904954)
0.1	0.4	GO:0061144	alveolar secondary septum development(GO:0061144)
0.1	0.4	GO:0071492	cellular response to UV-A(GO:0071492)
0.1	0.5	GO:1904451	regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.1	0.4	GO:0043376	regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1	0.2	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.1	0.3	GO:0002276	basophil activation involved in immune response(GO:0002276)
0.1	0.6	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1	0.3	GO:1903168	enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.1	1.3	GO:0021520	spinal cord motor neuron cell fate specification(GO:0021520)
0.1	0.3	GO:0042374	phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1	0.4	GO:1904936	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.1	0.3	GO:0071918	urea transmembrane transport(GO:0071918)
0.1	0.3	GO:0060722	spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.1	0.3	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.1	0.3	GO:2001055	positive regulation of mesenchymal cell apoptotic process(GO:2001055)
0.1	0.6	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.1	0.6	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1	0.3	GO:0060573	ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1	0.3	GO:0097494	positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944) regulation of vesicle size(GO:0097494)
0.1	0.3	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.1	1.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.1	0.2	GO:1904274	tricellular tight junction assembly(GO:1904274)
0.1	0.3	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.1	0.6	GO:0051611	regulation of serotonin uptake(GO:0051611)
0.1	0.4	GO:0009092	homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
0.1	0.4	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1	0.2	GO:1900740	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1	0.5	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.1	0.2	GO:2001183	negative regulation of interleukin-12 secretion(GO:2001183)
0.1	0.3	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1	0.2	GO:0070368	positive regulation of hepatocyte differentiation(GO:0070368)
0.1	0.6	GO:0070445	cerebral cortex regionalization(GO:0021796) oligodendrocyte progenitor proliferation(GO:0070444) regulation of oligodendrocyte progenitor proliferation(GO:0070445)
0.0	0.2	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.3	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.2	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.0	0.4	GO:0061143	alveolar primary septum development(GO:0061143)
0.0	0.2	GO:0045578	bundle of His development(GO:0003166) negative regulation of B cell differentiation(GO:0045578) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.2	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.3	GO:0097490	trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0	0.6	GO:0060732	positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0	0.3	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0015910	peroxisomal long-chain fatty acid import(GO:0015910)
0.0	0.3	GO:0089700	protein kinase D signaling(GO:0089700)
0.0	0.1	GO:2000987	positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0	0.3	GO:0042473	outer ear morphogenesis(GO:0042473)
0.0	0.2	GO:1901842	negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0	0.3	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.3	GO:2000667	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0	0.7	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.1	GO:0006049	UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0	0.2	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.3	GO:0015671	oxygen transport(GO:0015671)
0.0	0.3	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0	0.4	GO:2000582	positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0	0.4	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	0.1	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.0	0.2	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.2	GO:0048539	bone marrow development(GO:0048539)
0.0	0.2	GO:0097647	calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0	0.1	GO:0015744	succinate transport(GO:0015744)
0.0	1.2	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0	0.3	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.2	GO:0033762	response to glucagon(GO:0033762)
0.0	0.2	GO:0016480	negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0	0.1	GO:0071163	pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.0	0.1	GO:0032439	endosome localization(GO:0032439)
0.0	0.1	GO:1901608	dense core granule localization(GO:0032253) positive regulation of histone H3-K9 trimethylation(GO:1900114) regulation of vesicle transport along microtubule(GO:1901608) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811)
0.0	0.1	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.0	0.2	GO:0015669	gas transport(GO:0015669) carbon dioxide transport(GO:0015670)
0.0	0.4	GO:0098596	vocal learning(GO:0042297) imitative learning(GO:0098596)
0.0	0.1	GO:0050911	detection of chemical stimulus involved in sensory perception of smell(GO:0050911)
0.0	0.2	GO:0097421	liver regeneration(GO:0097421)
0.0	0.5	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.2	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.4	GO:0070633	transepithelial transport(GO:0070633)
0.0	0.2	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.2	GO:1900121	negative regulation of receptor binding(GO:1900121)
0.0	0.3	GO:0060033	anatomical structure regression(GO:0060033)
0.0	0.5	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.3	GO:0071378	growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0	0.3	GO:0006516	glycoprotein catabolic process(GO:0006516)
0.0	0.2	GO:0005513	detection of calcium ion(GO:0005513)
0.0	1.1	GO:1902653	cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0	0.3	GO:0048672	positive regulation of collateral sprouting(GO:0048672)
0.0	0.1	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.0	0.6	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	0.1	GO:0048102	autophagic cell death(GO:0048102)
0.0	0.4	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.2	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.2	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.0	0.2	GO:0034982	mitochondrial protein processing(GO:0034982)
0.0	0.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.0	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.1	GO:0030578	PML body organization(GO:0030578)
0.0	0.1	GO:0006621	protein retention in ER lumen(GO:0006621)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.0	GO:0098974	postsynaptic actin cytoskeleton organization(GO:0098974)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.4	GO:0009299	mRNA transcription(GO:0009299)
0.0	0.2	GO:0035721	intraciliary retrograde transport(GO:0035721)
0.0	0.2	GO:0043011	myeloid dendritic cell differentiation(GO:0043011)
0.0	0.2	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0	0.3	GO:0006783	heme biosynthetic process(GO:0006783)
0.0	0.1	GO:0031508	pericentric heterochromatin assembly(GO:0031508)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0033257	Bcl3/NF-kappaB2 complex(GO:0033257)
0.2	0.8	GO:0031680	G-protein beta/gamma-subunit complex(GO:0031680)
0.1	0.5	GO:1990794	lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.1	0.4	GO:1990257	piccolo-bassoon transport vesicle(GO:1990257)
0.1	0.4	GO:1902737	dendritic filopodium(GO:1902737)
0.1	0.9	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.1	0.3	GO:0045160	myosin I complex(GO:0045160)
0.1	0.3	GO:0044218	other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1	0.6	GO:0031415	NatA complex(GO:0031415)
0.1	0.6	GO:0000796	condensin complex(GO:0000796)
0.1	0.4	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1	0.6	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.2	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.4	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.2	GO:0005745	m-AAA complex(GO:0005745)
0.0	0.7	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.2	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.4	GO:0045179	apical cortex(GO:0045179)
0.0	0.3	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0008622	epsilon DNA polymerase complex(GO:0008622)
0.0	0.1	GO:0097129	cyclin D2-CDK4 complex(GO:0097129)
0.0	0.1	GO:0070820	cytolytic granule(GO:0044194) tertiary granule(GO:0070820)
0.0	0.1	GO:0036387	nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
0.0	0.3	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.2	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	0.7	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.3	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.2	GO:0045275	respiratory chain complex III(GO:0045275)
0.0	0.9	GO:0034707	chloride channel complex(GO:0034707)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.6	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.9	GO:0099501	synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0	0.2	GO:0042555	MCM complex(GO:0042555)
0.0	0.6	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.2	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.6	GO:0008142	oxysterol binding(GO:0008142)
0.2	0.7	GO:0004991	parathyroid hormone receptor activity(GO:0004991)
0.1	0.8	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1	0.4	GO:0005118	sevenless binding(GO:0005118)
0.1	0.4	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.1	0.3	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.1	0.6	GO:1990190	peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1	0.4	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.3	GO:0036478	tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1	0.3	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.1	0.4	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.1	0.3	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1	0.3	GO:0008967	phosphoglycolate phosphatase activity(GO:0008967)
0.1	0.5	GO:0051430	corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1	0.6	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1	0.3	GO:0004096	catalase activity(GO:0004096)
0.1	0.3	GO:0008269	JAK pathway signal transduction adaptor activity(GO:0008269)
0.1	0.4	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.2	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.1	0.2	GO:0070052	collagen V binding(GO:0070052)
0.0	0.3	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	1.2	GO:0070410	JUN kinase binding(GO:0008432) co-SMAD binding(GO:0070410)
0.0	0.2	GO:0005093	Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0	0.3	GO:0015204	urea transmembrane transporter activity(GO:0015204)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0003827	alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0	0.1	GO:0030348	syntaxin-3 binding(GO:0030348)
0.0	0.6	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.3	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.2	GO:0000155	phosphorelay sensor kinase activity(GO:0000155)
0.0	0.7	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.2	GO:0047134	protein-disulfide reductase activity(GO:0047134)
0.0	0.9	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.3	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	1.3	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0019970	interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.0	0.3	GO:0045499	chemorepellent activity(GO:0045499)
0.0	0.1	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.6	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.5	GO:0004697	protein kinase C activity(GO:0004697)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.4	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.4	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.6	GO:0016628	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0005372	water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.0	0.2	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.1	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.3	GO:0016918	retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0	0.1	GO:0004032	alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.2	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.6	GO:0005104	fibroblast growth factor receptor binding(GO:0005104)
0.0	0.5	GO:0016866	intramolecular transferase activity(GO:0016866)
0.0	0.5	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.2	GO:1990459	transferrin receptor binding(GO:1990459)
0.0	0.2	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.2	GO:0070034	telomerase RNA binding(GO:0070034)
0.0	0.2	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.0	GO:0004658	propionyl-CoA carboxylase activity(GO:0004658)
0.0	0.4	GO:0019707	protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0	0.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0042610	CD8 receptor binding(GO:0042610)
0.0	0.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.2	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.8	GO:0030374	ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0	0.0	GO:0000179	rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0	0.1	GO:0031705	bombesin receptor binding(GO:0031705)
0.0	0.5	GO:0005246	calcium channel regulator activity(GO:0005246)
0.0	0.0	GO:0098918	structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.4	GO:0070330	aromatase activity(GO:0070330)
0.0	0.4	GO:0051183	vitamin transporter activity(GO:0051183)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.9	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.5	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.6	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.3	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.5	PID WNT SIGNALING PATHWAY	Wnt signaling network
0.0	0.8	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.0	0.4	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.9	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.0	1.1	PID AR PATHWAY	Coregulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.1	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	1.1	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	1.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.4	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.9	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	1.1	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0	0.2	REACTOME GLYCOPROTEIN HORMONES	Genes involved in Glycoprotein hormones
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.7	REACTOME FGFR LIGAND BINDING AND ACTIVATION	Genes involved in FGFR ligand binding and activation
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.9	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	1.3	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.5	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	1.3	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.4	REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE	Genes involved in Cytochrome P450 - arranged by substrate type
0.0	0.4	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.4	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.0	0.6	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)