ISMARA results: Zfx

Project

GSE58827: Dynamics of the Mouse Liver

Navigation

Downloads

Results for Zfx_Zfp711

Z-value: 2.29

Motif logo

Transcription factors associated with Zfx_Zfp711

Gene Symbol	Gene ID	Gene Info
Zfx Ensembl NCBI MGI UniProt	ENSMUSG00000079509.4	zinc finger protein X-linked
Zfp711 Ensembl NCBI MGI UniProt	ENSMUSG00000025529.8	zinc finger protein 711

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Zfx	mm10_v2_chrX_-_94123087_94123159	-0.50	1.9e-03	Click!
Zfp711	mm10_v2_chrX_+_112615301_112615301	-0.49	2.4e-03	Click!

Activity profile of Zfx_Zfp711 motif

Sorted Z-values of Zfx_Zfp711 motif

Top targets:

Search:

Show entries

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr10_-_88503952 Show fit	8.40	ENSMUST00000020253.8	Chpt1 Ensembl NCBI MGI UniProt Show fit	choline phosphotransferase 1
chr3_-_18243289 Show fit	7.82	ENSMUST00000035625.6	Cyp7b1 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 7, subfamily b, polypeptide 1
chr4_+_43631935 Show fit	7.38	ENSMUST00000030191.8	Npr2 Ensembl NCBI MGI UniProt Show fit	natriuretic peptide receptor 2
chr4_-_61674094 Show fit	6.89	ENSMUST00000098040.3	Mup18 Ensembl NCBI MGI UniProt Show fit	major urinary protein 18
chr4_-_60222580 Show fit	6.35	ENSMUST00000095058.4 ENSMUST00000163931.1	Mup8 Ensembl NCBI MGI UniProt Show fit	major urinary protein 8
chr10_-_88503912 Show fit	6.16	ENSMUST00000117579.1 ENSMUST00000073783.5	Chpt1 Ensembl NCBI MGI UniProt Show fit	choline phosphotransferase 1
chr4_+_63344548 Show fit	5.96	ENSMUST00000030044.2	Orm1 Ensembl NCBI MGI UniProt Show fit	orosomucoid 1
chr4_-_60499332 Show fit	5.74	ENSMUST00000135953.1	Mup1 Ensembl NCBI MGI UniProt Show fit	major urinary protein 1
chr7_-_97417730 Show fit	5.53	ENSMUST00000043077.7	Thrsp Ensembl NCBI MGI UniProt Show fit	thyroid hormone responsive
chr12_+_108334341 Show fit	5.45	ENSMUST00000021684.4	Cyp46a1 Ensembl NCBI MGI UniProt Show fit	cytochrome P450, family 46, subfamily a, polypeptide 1

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfx_Zfp711

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
3.1	18.7	GO:0006663	platelet activating factor biosynthetic process(GO:0006663)
1.4	14.5	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.4	14.5	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.3	12.8	GO:0043171	peptide catabolic process(GO:0043171)
0.1	12.6	GO:0042787	protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.2	11.3	GO:0070936	protein K48-linked ubiquitination(GO:0070936)
0.2	9.7	GO:0006890	retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2	9.6	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
1.0	9.4	GO:0035754	B cell chemotaxis(GO:0035754)
0.2	9.4	GO:0006749	glutathione metabolic process(GO:0006749)

Showing 1 to 10 of 1,111 entries

Gene overrepresentation in cellular component category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	141.6	GO:0005739	mitochondrion(GO:0005739)
0.2	31.3	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.2	22.5	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.1	20.4	GO:0045177	apical part of cell(GO:0045177)
0.3	16.2	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.2	12.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.6	10.8	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.1	10.1	GO:0005765	lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.4	10.0	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.2	9.9	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)

Showing 1 to 10 of 340 entries

Gene overrepresentation in molecular function category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	38.0	GO:0061630	ubiquitin protein ligase activity(GO:0061630)
0.3	21.9	GO:0008395	steroid hydroxylase activity(GO:0008395)
3.9	19.4	GO:0004142	diacylglycerol cholinephosphotransferase activity(GO:0004142)
0.2	16.4	GO:0101005	thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
2.4	12.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.5	11.6	GO:0070006	metalloaminopeptidase activity(GO:0070006)
0.2	11.5	GO:0035064	methylated histone binding(GO:0035064)
0.0	11.4	GO:0019787	ubiquitin-like protein transferase activity(GO:0019787)
0.3	11.3	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.3	10.6	GO:0016896	exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)

Showing 1 to 10 of 630 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	14.4	PID IL1 PATHWAY	IL1-mediated signaling events
0.1	10.6	PID LKB1 PATHWAY	LKB1 signaling events
0.2	10.5	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	8.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.3	7.3	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	6.7	ST JNK MAPK PATHWAY	JNK MAPK Pathway
0.2	5.7	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.2	5.6	PID ARF 3PATHWAY	Arf1 pathway
0.1	5.2	PID FOXO PATHWAY	FoxO family signaling
0.0	5.0	PID MYC ACTIV PATHWAY	Validated targets of C-MYC transcriptional activation

Showing 1 to 10 of 95 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Search:

Show entries

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	24.2	REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION	Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.5	17.2	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
1.2	15.9	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.1	15.2	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.5	14.9	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.2	14.1	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.5	13.1	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.2	12.7	REACTOME METABOLISM OF VITAMINS AND COFACTORS	Genes involved in Metabolism of vitamins and cofactors
0.8	11.5	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.2	11.0	REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC	Genes involved in Regulation of ornithine decarboxylase (ODC)

Showing 1 to 10 of 153 entries

Results for Zfx_Zfp711

Z-value: 2.29

Motif logo

Transcription factors associated with Zfx_Zfp711

Activity-expression correlation:

Activity profile of Zfx_Zfp711 motif

Sorted Z-values of Zfx_Zfp711 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfx_Zfp711

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: