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GSE58827: Dynamics of the Mouse Liver

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Results for Tlx1

Z-value: 0.79

Motif logo

Transcription factors associated with Tlx1

Gene Symbol Gene ID Gene Info
ENSMUSG00000025215.9 T cell leukemia, homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tlx1mm10_v2_chr19_+_45149833_45149878-0.251.4e-01Click!

Activity profile of Tlx1 motif

Sorted Z-values of Tlx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_55175019 10.19 ENSMUST00000003569.5
indolethylamine N-methyltransferase
chr7_+_119526269 9.80 ENSMUST00000066465.1
acyl-CoA synthetase medium-chain family member 5
chr9_-_57683644 8.08 ENSMUST00000034860.3
cytochrome P450, family 1, subfamily a, polypeptide 2
chr7_-_97417730 7.04 ENSMUST00000043077.7
thyroid hormone responsive
chr7_+_26835305 6.82 ENSMUST00000005685.8
cytochrome P450, family 2, subfamily a, polypeptide 5
chr10_-_40025253 4.63 ENSMUST00000163705.2
expressed sequence AI317395
chr10_-_81291227 4.39 ENSMUST00000045744.6
tight junction protein 3
chr5_+_146079254 3.95 ENSMUST00000035571.8
cytochrome P450, family 3, subfamily a, polypeptide 59
chr17_-_56121946 3.80 ENSMUST00000041357.7
leucine-rich alpha-2-glycoprotein 1
chr11_+_115462464 3.68 ENSMUST00000106532.3
ENSMUST00000092445.5
ENSMUST00000153466.1
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr10_+_128254131 3.31 ENSMUST00000060782.3
apolipoprotein N
chr6_-_85933379 3.16 ENSMUST00000162660.1
N-acetyltransferase 8B
chr14_+_65970610 3.14 ENSMUST00000127387.1
clusterin
chr11_+_99041237 3.11 ENSMUST00000017637.6
insulin-like growth factor binding protein 4
chr9_+_65265173 3.11 ENSMUST00000048762.1
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr14_+_65970804 3.04 ENSMUST00000138191.1
clusterin
chr14_+_65971164 3.02 ENSMUST00000144619.1
clusterin
chr14_+_65971049 2.98 ENSMUST00000128539.1
clusterin
chr5_-_77115145 2.84 ENSMUST00000081964.5
HOP homeobox
chr13_-_41847626 2.73 ENSMUST00000121404.1
androgen dependent TFPI regulating protein
chr4_-_57916283 2.72 ENSMUST00000063816.5
RIKEN cDNA D630039A03 gene
chr3_+_81996922 2.69 ENSMUST00000029641.3
acid-sensing (proton-gated) ion channel family member 5
chr8_+_94472763 2.66 ENSMUST00000053085.5
NLR family, CARD domain containing 5
chr14_+_51091077 2.63 ENSMUST00000022428.5
ENSMUST00000171688.1
ribonuclease, RNase A family 4
angiogenin, ribonuclease, RNase A family, 5
chr19_+_32619997 2.57 ENSMUST00000025833.6
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr2_-_25470031 2.56 ENSMUST00000114251.1
prostaglandin D2 synthase (brain)
chr7_+_26307190 2.55 ENSMUST00000098657.3
cytochrome P450, family 2, subfamily a, polypeptide 4
chr13_-_41847482 2.50 ENSMUST00000072012.3
androgen dependent TFPI regulating protein
chr16_-_18426372 2.45 ENSMUST00000000335.4
catechol-O-methyltransferase
chr2_+_27079371 2.44 ENSMUST00000091233.6
ADAMTS-like 2
chr10_-_89533550 2.41 ENSMUST00000105297.1
nuclear receptor subfamily 1, group H, member 4
chr2_-_25493905 2.37 ENSMUST00000028312.6
lipocalin 12
chr5_+_114923234 2.32 ENSMUST00000031540.4
ENSMUST00000112143.3
2'-5' oligoadenylate synthetase-like 1
chr2_-_25493432 2.27 ENSMUST00000114245.1
lipocalin 12
chr19_-_46672883 2.23 ENSMUST00000026012.7
cytochrome P450, family 17, subfamily a, polypeptide 1
chr13_-_41847599 2.23 ENSMUST00000179758.1
androgen dependent TFPI regulating protein
chr3_-_85746266 2.22 ENSMUST00000118408.1
family with sequence similarity 160, member A1
chr11_-_116654245 2.20 ENSMUST00000021166.5
cytoglobin
chr1_+_87574016 2.19 ENSMUST00000166259.1
ENSMUST00000172222.1
ENSMUST00000163606.1
neuraminidase 2
chr1_-_162859684 2.18 ENSMUST00000131058.1
flavin containing monooxygenase 1
chr6_+_55451978 2.11 ENSMUST00000070736.5
ENSMUST00000070756.5
ENSMUST00000166962.1
adenylate cyclase activating polypeptide 1 receptor 1
chr2_+_119167758 2.08 ENSMUST00000057454.3
GTP cyclohydrolase I feedback regulator
chr17_+_32685610 2.04 ENSMUST00000168171.1
cytochrome P450, family 4, subfamily f, polypeptide 15
chr7_-_80403315 2.01 ENSMUST00000147150.1
furin (paired basic amino acid cleaving enzyme)
chr17_+_32685655 2.00 ENSMUST00000008801.6
cytochrome P450, family 4, subfamily f, polypeptide 15
chr1_+_133246092 1.97 ENSMUST00000038295.8
ENSMUST00000105082.2
pleckstrin homology domain containing, family A member 6
chr10_+_116301374 1.96 ENSMUST00000092167.5
protein tyrosine phosphatase, receptor type, B
chr4_+_47208005 1.95 ENSMUST00000082303.6
ENSMUST00000102917.4
collagen, type XV, alpha 1
chr4_-_138367966 1.83 ENSMUST00000030535.3
cytidine deaminase
chr2_-_91195097 1.83 ENSMUST00000002177.2
ENSMUST00000111354.1
nuclear receptor subfamily 1, group H, member 3
chr14_+_8002949 1.75 ENSMUST00000026313.3
abhydrolase domain containing 6
chr10_-_77113676 1.72 ENSMUST00000072755.4
ENSMUST00000105409.1
collagen, type XVIII, alpha 1
chr11_-_9039585 1.70 ENSMUST00000043377.5
Sad1 and UNC84 domain containing 3
chr4_-_140617062 1.69 ENSMUST00000154979.1
Rho guanine nucleotide exchange factor (GEF) 10-like
chr13_+_19342154 1.68 ENSMUST00000103566.3
T cell receptor gamma, constant 4
chr14_+_8002890 1.66 ENSMUST00000166497.1
abhydrolase domain containing 6
chr4_-_129227883 1.66 ENSMUST00000106051.1
expressed sequence C77080
chr10_-_77113928 1.65 ENSMUST00000149744.1
collagen, type XVIII, alpha 1
chrX_+_36112110 1.63 ENSMUST00000033418.7
interleukin 13 receptor, alpha 1
chr5_-_139819906 1.61 ENSMUST00000147328.1
transmembrane protein 184a
chr13_+_12565868 1.60 ENSMUST00000071973.6
ERO1-like beta (S. cerevisiae)
chr11_-_75422524 1.60 ENSMUST00000125982.1
ENSMUST00000137103.1
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr11_-_75422586 1.60 ENSMUST00000138661.1
ENSMUST00000000769.7
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr4_+_41762309 1.59 ENSMUST00000108042.2
interleukin 11 receptor, alpha chain 1
chr3_+_123267445 1.58 ENSMUST00000047923.7
Sec24 related gene family, member D (S. cerevisiae)
chr11_-_68386974 1.51 ENSMUST00000135141.1
netrin 1
chr2_-_104742802 1.46 ENSMUST00000028595.7
DEP domain containing 7
chr2_-_91194767 1.44 ENSMUST00000111355.1
nuclear receptor subfamily 1, group H, member 3
chr7_+_28180272 1.42 ENSMUST00000173223.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr11_+_109485606 1.42 ENSMUST00000106697.1
arylsulfatase G
chr3_-_63964659 1.41 ENSMUST00000161659.1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr2_-_91195035 1.40 ENSMUST00000111356.1
nuclear receptor subfamily 1, group H, member 3
chr8_-_72435043 1.39 ENSMUST00000109974.1
calreticulin 3
chr3_-_63964768 1.37 ENSMUST00000029402.8
solute carrier family 33 (acetyl-CoA transporter), member 1
chr3_+_57736056 1.37 ENSMUST00000041826.9
ring finger protein 13
chr5_+_35814424 1.33 ENSMUST00000114203.1
actin-binding LIM protein 2
chr7_+_130936172 1.30 ENSMUST00000006367.7
HtrA serine peptidase 1
chr7_+_123462274 1.29 ENSMUST00000033023.3
aquaporin 8
chr7_-_127890918 1.29 ENSMUST00000121394.1
protease, serine, 53
chr13_+_43785107 1.28 ENSMUST00000015540.2
CD83 antigen
chr9_-_15301555 1.28 ENSMUST00000034414.8
RIKEN cDNA 4931406C07 gene
chr14_-_63177793 1.26 ENSMUST00000054963.9
farnesyl diphosphate farnesyl transferase 1
chr11_+_97030130 1.26 ENSMUST00000153482.1
secernin 2
chr3_-_107931579 1.23 ENSMUST00000133947.2
ENSMUST00000124215.1
ENSMUST00000106688.1
ENSMUST00000106687.2
glutathione S-transferase, mu 7
chr5_+_104775911 1.22 ENSMUST00000055593.7
predicted gene 8258
chr17_+_6106880 1.20 ENSMUST00000149756.1
tubby like protein 4
chr7_+_28180226 1.18 ENSMUST00000172467.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr13_+_16011851 1.17 ENSMUST00000042603.6
inhibin beta-A
chr3_-_88254706 1.16 ENSMUST00000171887.1
Rhesus blood group-associated B glycoprotein
chr3_-_151749877 1.16 ENSMUST00000029671.7
interferon-induced protein 44
chr7_-_127935429 1.13 ENSMUST00000141385.1
ENSMUST00000156152.1
protease, serine, 36
chr11_+_97029925 1.13 ENSMUST00000021249.4
secernin 2
chr11_+_28853189 1.13 ENSMUST00000020759.5
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
chr10_-_34096507 1.12 ENSMUST00000069125.6
family with sequence similarity 26, member E
chr11_+_115440540 1.11 ENSMUST00000093914.4
RIKEN cDNA 4933422H20 gene
chr17_-_25837082 1.11 ENSMUST00000183929.1
ENSMUST00000184865.1
ENSMUST00000026831.7
rhomboid, veinlet-like 1 (Drosophila)
chr6_-_83656082 1.10 ENSMUST00000014686.2
C-type lectin domain family 4, member f
chr19_+_44333092 1.08 ENSMUST00000058856.8
stearoyl-coenzyme A desaturase 4
chr3_-_107931817 1.07 ENSMUST00000004137.4
glutathione S-transferase, mu 7
chr19_+_5878622 1.05 ENSMUST00000136833.1
ENSMUST00000141362.1
solute carrier family 25, member 45
chr14_-_55884223 1.03 ENSMUST00000172378.1
cerebellin 3 precursor protein
chr5_+_34549595 1.01 ENSMUST00000179943.1
SH3-domain binding protein 2
chr5_+_102768771 1.01 ENSMUST00000112852.1
Rho GTPase activating protein 24
chr11_-_77894096 1.00 ENSMUST00000017597.4
pipecolic acid oxidase
chr6_+_48593927 0.99 ENSMUST00000135151.1
replication initiator 1
chr8_-_67818284 0.99 ENSMUST00000120071.1
pleckstrin and Sec7 domain containing 3
chr2_+_82053222 0.99 ENSMUST00000047527.7
zinc finger protein 804A
chr2_+_164832881 0.97 ENSMUST00000103092.1
ENSMUST00000151493.1
ENSMUST00000127650.1
cathepsin A
chr2_-_168734236 0.94 ENSMUST00000109175.2
ATPase, class II, type 9A
chr11_-_31824463 0.93 ENSMUST00000129425.1
ENSMUST00000126265.1
RIKEN cDNA D630024D03 gene
chr2_-_130664565 0.91 ENSMUST00000089559.4
DDRGK domain containing 1
chr8_-_67818218 0.90 ENSMUST00000059374.4
pleckstrin and Sec7 domain containing 3
chr2_+_164832862 0.89 ENSMUST00000103093.3
ENSMUST00000017904.2
cathepsin A
chr8_-_95434869 0.89 ENSMUST00000034249.6
gene trap locus 3
chr11_+_97798995 0.87 ENSMUST00000143571.1
LIM and SH3 protein 1
chr5_+_35814356 0.87 ENSMUST00000130233.1
actin-binding LIM protein 2
chr6_-_88518760 0.87 ENSMUST00000032168.5
Sec61 alpha 1 subunit (S. cerevisiae)
chr5_+_124483458 0.86 ENSMUST00000111453.1
small nuclear ribonucleoprotein 35 (U11/U12)
chr4_-_115647709 0.85 ENSMUST00000102707.3
cytochrome P450, family 4, subfamily b, polypeptide 1
chr1_+_185454803 0.85 ENSMUST00000061093.6
solute carrier family 30, member 10
chr10_+_61089327 0.85 ENSMUST00000020298.6
pterin 4 alpha carbinolamine dehydratase/dimerization cofactor of hepatocyte nuclear factor 1 alpha (TCF1) 1
chr1_-_168431695 0.85 ENSMUST00000176790.1
pre B cell leukemia homeobox 1
chr4_-_103215147 0.84 ENSMUST00000150285.1
solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chr18_+_33464163 0.84 ENSMUST00000097634.3
predicted gene 10549
chr15_-_76229492 0.83 ENSMUST00000074834.5
plectin
chr5_-_24581879 0.83 ENSMUST00000088299.4
predicted gene 10221
chrX_+_73228272 0.83 ENSMUST00000105111.2
factor 8-associated gene A
chr1_+_132007606 0.82 ENSMUST00000086556.5
ELK4, member of ETS oncogene family
chr6_-_33060256 0.80 ENSMUST00000066379.4
coiled-coil-helix-coiled-coil-helix domain containing 3
chr6_-_33060172 0.80 ENSMUST00000115091.1
ENSMUST00000127666.1
coiled-coil-helix-coiled-coil-helix domain containing 3
chr9_-_124311750 0.80 ENSMUST00000177714.1
RIKEN cDNA 2010315B03 gene
chr11_+_58421103 0.79 ENSMUST00000013797.2
RIKEN cDNA 1810065E05 gene
chr5_-_38491948 0.79 ENSMUST00000129099.1
solute carrier family 2 (facilitated glucose transporter), member 9
chr19_-_3912711 0.78 ENSMUST00000075092.6
NADH dehydrogenase (ubiquinone) Fe-S protein 8
chr11_-_5741141 0.77 ENSMUST00000140922.1
ENSMUST00000093362.5
upregulator of cell proliferation
chr5_-_66451629 0.76 ENSMUST00000160063.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr8_+_104831572 0.76 ENSMUST00000059449.6
carboxyesterase 2B
chr1_-_5019342 0.75 ENSMUST00000002533.8
regulator of G-protein signaling 20
chr1_-_162859919 0.75 ENSMUST00000134098.1
ENSMUST00000111518.1
flavin containing monooxygenase 1
chr9_+_57521232 0.74 ENSMUST00000000090.6
cytochrome c oxidase subunit Va
chr1_-_87573825 0.73 ENSMUST00000068681.5
neuronal guanine nucleotide exchange factor
chr11_-_97150025 0.73 ENSMUST00000118375.1
TBK1 binding protein 1
chr9_+_44773027 0.73 ENSMUST00000125877.1
intraflagellar transport 46
chr8_+_12573017 0.73 ENSMUST00000010579.6
sperm acrosome associated 7
chr2_+_85050439 0.73 ENSMUST00000111605.2
tankyrase 1 binding protein 1
chr4_+_59581645 0.72 ENSMUST00000107528.1
hydroxysteroid dehydrogenase like 2
chr8_-_93810225 0.71 ENSMUST00000181864.1
predicted gene, 26843
chr5_+_34549568 0.70 ENSMUST00000118545.1
SH3-domain binding protein 2
chr7_+_62476306 0.70 ENSMUST00000097132.3
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g, pseudogene 1
chr12_-_56535047 0.68 ENSMUST00000178477.2
NK2 homeobox 1
chr17_-_25919506 0.68 ENSMUST00000164982.1
ENSMUST00000179998.1
ENSMUST00000167626.1
ENSMUST00000164738.1
ENSMUST00000026826.7
ENSMUST00000167018.1
Rab40c, member RAS oncogene family
chr6_+_147091379 0.67 ENSMUST00000036003.7
kelch-like 42
chr7_+_125829653 0.67 ENSMUST00000124223.1
RIKEN cDNA D430042O09 gene
chr9_+_44773191 0.66 ENSMUST00000147559.1
intraflagellar transport 46
chr11_+_116657106 0.66 ENSMUST00000116318.2
predicted gene 11744
chr15_+_80671829 0.65 ENSMUST00000023044.5
family with sequence similarity 83, member F
chr17_+_34969912 0.65 ENSMUST00000173680.1
predicted gene 20481
chr9_-_98955302 0.65 ENSMUST00000181706.1
forkhead box L2 opposite strand transcript
chr1_-_136131171 0.64 ENSMUST00000146091.3
ENSMUST00000165464.1
ENSMUST00000166747.1
ENSMUST00000134998.1
predicted gene 15850
chr13_+_4191163 0.64 ENSMUST00000021634.2
aldo-keto reductase family 1, member C13
chr14_-_8172986 0.63 ENSMUST00000022268.8
pyruvate dehydrogenase (lipoamide) beta
chr9_+_121710389 0.63 ENSMUST00000035113.9
differentially expressed in B16F10 1
chr1_-_56969864 0.62 ENSMUST00000177424.1
special AT-rich sequence binding protein 2
chr16_+_23429133 0.62 ENSMUST00000038730.6
receptor transporter protein 1
chr4_+_59581563 0.61 ENSMUST00000030078.5
hydroxysteroid dehydrogenase like 2
chr1_+_163929765 0.61 ENSMUST00000027876.4
ENSMUST00000170359.1
SCY1-like 3 (S. cerevisiae)
chr11_-_120713725 0.60 ENSMUST00000106154.1
ENSMUST00000106155.3
ENSMUST00000055424.6
ENSMUST00000026137.7
stimulated by retinoic acid 13
chr19_-_42752710 0.59 ENSMUST00000076505.3
pyridine nucleotide-disulphide oxidoreductase domain 2
chr14_+_124005355 0.58 ENSMUST00000166105.1
predicted gene, 17615
chrX_+_56963325 0.57 ENSMUST00000096431.3
G protein-coupled receptor 112
chr2_-_118762607 0.57 ENSMUST00000059997.8
RIKEN cDNA A430105I19 gene
chr9_-_99436749 0.56 ENSMUST00000122384.1
muscle and microspikes RAS
chr7_+_141467362 0.56 ENSMUST00000106000.2
ENSMUST00000177840.1
CD151 antigen
chr1_-_130940073 0.56 ENSMUST00000112465.1
interleukin 19
chr7_+_120173847 0.56 ENSMUST00000033201.5
ankyrin repeat and sterile alpha motif domain containing 4B
chr3_+_133310093 0.56 ENSMUST00000029644.9
ENSMUST00000122334.1
pyrophosphatase (inorganic) 2
chr11_-_64436653 0.55 ENSMUST00000177999.1
RIKEN cDNA F930015N05 gene
chr2_-_150451486 0.55 ENSMUST00000109916.1
zinc finger protein 442
chrX_+_109095359 0.55 ENSMUST00000033598.8
SH3-binding domain glutamic acid-rich protein like
chr2_+_90847207 0.54 ENSMUST00000150232.1
ENSMUST00000111467.3
mitochondrial carrier homolog 2 (C. elegans)
chr6_+_4601124 0.54 ENSMUST00000181734.1
ENSMUST00000141359.1
CAS1 domain containing 1
chr14_-_30008817 0.54 ENSMUST00000122205.1
ENSMUST00000016110.6
interleukin 17 receptor B
chr12_+_108792946 0.53 ENSMUST00000021692.7
YY1 transcription factor
chr1_-_74749221 0.53 ENSMUST00000081636.6
protein kinase, AMP-activated, gamma 3 non-catatlytic subunit
chr11_-_31824518 0.52 ENSMUST00000134944.1
RIKEN cDNA D630024D03 gene
chr17_+_17121415 0.52 ENSMUST00000147630.1
zinc finger protein 97
chr16_+_18836573 0.52 ENSMUST00000055413.6
RIKEN cDNA 2510002D24 gene
chr5_-_90640464 0.52 ENSMUST00000031317.6
Ras association (RalGDS/AF-6) domain family member 6
chr5_-_125389915 0.52 ENSMUST00000136312.1
ubiquitin C
chr3_+_121671317 0.51 ENSMUST00000098646.3
RIKEN cDNA 4930432M17 gene
chr17_+_24470393 0.51 ENSMUST00000053024.6
phosphoglycolate phosphatase
chr15_+_99591028 0.51 ENSMUST00000169082.1
aquaporin 5
chr8_-_57962564 0.50 ENSMUST00000098757.3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 6
chr4_+_133584419 0.50 ENSMUST00000105899.1
GPN-loop GTPase 2
chr11_+_53770458 0.50 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
interferon regulatory factor 1
chrX_+_94234594 0.50 ENSMUST00000153900.1
kelch-like 15
chr14_-_122451109 0.49 ENSMUST00000081580.2
predicted gene 5089
chr4_-_147848358 0.48 ENSMUST00000105718.1
ENSMUST00000135798.1
zinc finger protein 933
chr16_+_4684070 0.48 ENSMUST00000060067.5
ENSMUST00000115854.3
DnaJ (Hsp40) homolog, subfamily A, member 3
chr2_-_167060417 0.48 ENSMUST00000155281.1
zinc finger, NFX1-type containing 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Tlx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
2.0 12.2 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
1.6 4.7 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.8 2.5 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.8 2.4 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.7 2.6 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.6 1.8 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.5 2.6 GO:0000103 sulfate assimilation(GO:0000103)
0.5 2.6 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.5 2.0 GO:0090472 dibasic protein processing(GO:0090472)
0.5 3.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 1.6 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.4 1.6 GO:0030070 insulin processing(GO:0030070)
0.4 2.3 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.4 2.8 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.3 3.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.3 1.0 GO:0006553 lysine metabolic process(GO:0006553)
0.3 2.7 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.3 9.4 GO:0035634 response to stilbenoid(GO:0035634)
0.3 3.2 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.3 1.3 GO:0016128 phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129)
0.3 2.5 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.3 1.9 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.3 1.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.3 0.9 GO:0018879 biphenyl metabolic process(GO:0018879)
0.3 0.9 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.3 2.2 GO:0015671 oxygen transport(GO:0015671)
0.3 1.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.3 1.6 GO:0018992 germ-line sex determination(GO:0018992)
0.2 0.7 GO:0021759 globus pallidus development(GO:0021759)
0.2 2.9 GO:0070995 NADPH oxidation(GO:0070995)
0.2 1.8 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.2 0.9 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.2 3.1 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.2 7.0 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.2 1.2 GO:0051799 striatal medium spiny neuron differentiation(GO:0021773) negative regulation of hair follicle development(GO:0051799)
0.2 2.6 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.2 1.3 GO:0015722 canalicular bile acid transport(GO:0015722)
0.2 0.5 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.2 1.3 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.2 1.3 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.2 3.4 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.2 0.9 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.9 GO:0039019 pronephric nephron development(GO:0039019)
0.1 2.2 GO:0042448 progesterone metabolic process(GO:0042448)
0.1 0.5 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.4 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.5 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.1 1.7 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.1 0.5 GO:0060331 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.1 3.8 GO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.1 10.6 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.1 1.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 1.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.6 GO:1904970 brush border assembly(GO:1904970)
0.1 1.1 GO:0051132 NK T cell activation(GO:0051132)
0.1 0.4 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 1.6 GO:0042407 cristae formation(GO:0042407)
0.1 0.3 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.8 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.1 0.5 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 0.5 GO:0035106 operant conditioning(GO:0035106)
0.1 0.5 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.8 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 1.6 GO:0046697 decidualization(GO:0046697)
0.1 0.5 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.1 0.5 GO:0032790 ribosome disassembly(GO:0032790)
0.1 0.4 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 1.7 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1 0.4 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.1 0.7 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.1 GO:0033686 positive regulation of luteinizing hormone secretion(GO:0033686)
0.1 1.9 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.8 GO:0070932 histone H3 deacetylation(GO:0070932)
0.1 0.2 GO:0046333 octopamine biosynthetic process(GO:0006589) octopamine metabolic process(GO:0046333)
0.1 1.4 GO:0001539 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.1 0.5 GO:0015669 gas transport(GO:0015669) carbon dioxide transport(GO:0015670)
0.1 0.2 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.1 2.6 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.5 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.1 0.2 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.7 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.1 0.7 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.6 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 8.2 GO:0009308 amine metabolic process(GO:0009308)
0.0 1.1 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.8 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:0050968 detection of chemical stimulus involved in sensory perception of pain(GO:0050968)
0.0 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 1.0 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.0 0.1 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 2.6 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 0.3 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.3 GO:0045002 double-strand break repair via single-strand annealing(GO:0045002)
0.0 0.8 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.6 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.6 GO:0042226 interleukin-6 biosynthetic process(GO:0042226)
0.0 0.7 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 1.2 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.7 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.9 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.3 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 1.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 2.4 GO:2000045 regulation of G1/S transition of mitotic cell cycle(GO:2000045)
0.0 0.8 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.1 GO:0060800 astrocyte fate commitment(GO:0060018) regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.3 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 2.8 GO:0030509 BMP signaling pathway(GO:0030509)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.5 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.1 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 12.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.9 2.6 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.4 1.3 GO:0046691 intracellular canaliculus(GO:0046691)
0.4 1.2 GO:0043512 inhibin A complex(GO:0043512)
0.2 3.2 GO:0043203 axon hillock(GO:0043203)
0.2 1.6 GO:0061617 MICOS complex(GO:0061617)
0.1 1.6 GO:0000243 commitment complex(GO:0000243)
0.1 1.7 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 9.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 2.0 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.2 GO:0043159 acrosomal matrix(GO:0043159)
0.1 0.4 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.1 2.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.5 GO:0097542 ciliary tip(GO:0097542)
0.1 0.2 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 0.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 2.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.3 GO:0030891 VCB complex(GO:0030891)
0.1 2.4 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 4.9 GO:0005581 collagen trimer(GO:0005581)
0.0 5.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 1.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.8 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.6 GO:0031011 Ino80 complex(GO:0031011)
0.0 10.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.8 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.9 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 5.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.8 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.2 GO:0016529 sarcoplasmic reticulum(GO:0016529)
0.0 0.2 GO:0097449 astrocyte projection(GO:0097449)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 2.4 GO:0005923 bicellular tight junction(GO:0005923)
0.0 1.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.7 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.4 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 10.2 GO:0008172 S-methyltransferase activity(GO:0008172)
1.4 9.8 GO:0003996 acyl-CoA ligase activity(GO:0003996)
1.3 8.1 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
1.3 3.9 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.9 4.7 GO:0032810 sterol response element binding(GO:0032810)
0.8 2.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.6 2.6 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.6 2.6 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.6 2.4 GO:0050436 microfibril binding(GO:0050436)
0.5 2.2 GO:0004096 catalase activity(GO:0004096)
0.5 12.2 GO:0051787 misfolded protein binding(GO:0051787)
0.5 2.5 GO:0052794 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.5 2.4 GO:0038181 bile acid receptor activity(GO:0038181)
0.5 2.8 GO:0051185 coenzyme transporter activity(GO:0051185)
0.4 1.6 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.3 3.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.3 1.8 GO:0004126 cytidine deaminase activity(GO:0004126)
0.3 9.4 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.3 2.7 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.3 2.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 1.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.3 1.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.3 1.0 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 4.6 GO:0001972 retinoic acid binding(GO:0001972)
0.2 3.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 2.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 1.3 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.2 0.8 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.2 1.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.1 GO:0005534 galactose binding(GO:0005534)
0.2 0.6 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 1.9 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 2.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.6 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 2.0 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 0.5 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.1 0.6 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 2.4 GO:0016805 dipeptidase activity(GO:0016805)
0.1 0.7 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 1.8 GO:0015250 water channel activity(GO:0015250)
0.1 1.6 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 1.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 3.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.1 0.3 GO:0008534 oxidized purine nucleobase lesion DNA N-glycosylase activity(GO:0008534)
0.1 2.3 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 0.5 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.1 0.9 GO:0015643 toxic substance binding(GO:0015643)
0.1 0.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 1.5 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 3.8 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.1 0.2 GO:0004500 dopamine beta-monooxygenase activity(GO:0004500)
0.1 3.7 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.1 1.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.1 1.0 GO:0043495 protein anchor(GO:0043495)
0.1 1.9 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 1.2 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.1 0.8 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 0.7 GO:0003796 lysozyme activity(GO:0003796)
0.0 1.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.7 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.0 0.5 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.0 0.5 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0016453 acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0 1.2 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 2.6 GO:0005507 copper ion binding(GO:0005507)
0.0 0.9 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.0 1.8 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.0 0.8 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 1.7 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.2 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 2.7 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.5 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.4 GO:0022829 wide pore channel activity(GO:0022829)
0.0 2.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0070679 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 1.7 GO:0000149 SNARE binding(GO:0000149)
0.0 0.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.0 GO:0004947 bradykinin receptor activity(GO:0004947)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 7.1 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.1 5.0 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 3.1 PID WNT SIGNALING PATHWAY Wnt signaling network
0.1 8.1 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.3 PID ALK1 PATHWAY ALK1 signaling events
0.0 5.4 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.3 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 1.4 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.6 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.3 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.2 2.6 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.2 2.2 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.2 1.2 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 1.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.2 2.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 1.8 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 3.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.7 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.1 3.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.1 11.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.1 3.1 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.5 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 1.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 3.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 2.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 5.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.1 0.8 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 1.3 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 2.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.5 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.6 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.5 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.8 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.5 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 1.1 REACTOME BIOLOGICAL OXIDATIONS Genes involved in Biological oxidations
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.8 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.1 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism